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Signaling reactions induced in human fibroblasts during adhesion to cementum-derived attachment protein. | Cementum-derived attachment protein (CAP) is a Mr 56,000 collagenous protein which promotes the adhesion and spreading of mesenchymal cell types. The CAP promotes the adhesion of osteoblasts and periodontal ligament cells better than gingival fibroblasts, while epithelial cells do not adhere to CAP-coated surfaces. To ... | ['Calcium-Calmodulin-Dependent Protein Kinases', 'Cell Adhesion', 'Cell Adhesion Molecules', 'Collagen', 'Dental Cementum', 'Fibroblasts', 'Humans', 'Phosphorylation', 'Signal Transduction'] | 9,893,067 | [['D08.811.913.696.620.682.700.125', 'D12.644.360.100', 'D12.776.476.100'], ['G04.022'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['D05.750.078.280', 'D12.776.860.300.250'], ['A14.549.167.646.267', 'A14.549.167.900.250'], ['A11.329.228'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of rapid canine fecal source identification PCR-based assays. | The extent to which dogs contribute to aquatic fecal contamination is unknown despite the potential for zoonotic transfer of harmful human pathogens. We used genome fragment enrichment (GFE) to identify novel nonribosomal microbial genetic markers potentially useful for detecting dog fecal contamination with PCR-based ... | ['Animals', 'Base Sequence', 'Biological Assay', 'Cyclonic Storms', 'DNA, Bacterial', 'Dogs', 'Feces', 'Genetic Markers', 'Genome', 'Humans', 'Open Reading Frames', 'Polymerase Chain Reaction', 'Sensitivity and Specificity', 'Sewage', 'Water Microbiology', 'Water Quality'] | 25,203,917 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.091'], ['G16.500.175.500', 'N06.230.100.230.100'], ['D13.444.308.212'], ['B01.050.150.900.649.313.750.250.216.200'], ['A12.459'], ['D23.101.387', 'G05.695.450'], ['G05.360.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.335... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Heterogeneity of 3'untranslated region of bovine acidic FGF transcripts. | A bovine aFGF genomic clone (14.2 Kb) has been isolated and characterized. This clone contains exons 2 and 3 interrupted by 6.7 Kb long intron. Exon 3 contains part of the coding region and the 3' untranslated region (3'UTR). Two overlapping cDNA clones specific for this 3'UTR have been isolated from bovine retina cDNA... | ['Amino Acid Sequence', 'Animals', 'Base Sequence', 'Blotting, Northern', 'Cattle', 'Cloning, Molecular', 'Exons', 'Fibroblast Growth Factor 1', 'Gene Library', 'Introns', 'Molecular Sequence Data', 'Poly A', 'Polymorphism, Genetic', 'Protein Biosynthesis', 'RNA', 'RNA, Messenger', 'Restriction Mapping', 'Retina', 'Tra... | 1,374,244 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['B01.050.150.900.649.313.500.380.271'], ['E05.393.220'], ['G05.360.340.024.340.137.232'], ['D12.644.276.624.110', 'D12.776.467.624.110', 'D23.529.6... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Infections due to Lancefield group G streptococci. | The group G streptococcus has surfaced in the past 10 to 15 years as an important opportunistic and nosocomial pathogen. Although more precise organism recognition accounts for a portion of these cases, there can be little doubt that the group G streptococcus has become a more prevalent pathogen. Commercial kits, utili... | ['Abortion, Septic', 'Adolescent', 'Adult', 'Aged', 'Arthritis, Infectious', 'Child', 'Child, Preschool', 'Connective Tissue Diseases', 'Endocarditis, Bacterial', 'Female', 'Humans', 'Infant', 'Infant, Newborn', 'Infant, Premature, Diseases', 'Male', 'Middle Aged', 'Osteomyelitis', 'Pleuropneumonia', 'Pregnancy', 'Puer... | 3,974,442 | [['C01.674.173', 'C13.703.039.256', 'C13.703.700.173'], ['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C01.100', 'C05.550.114.099'], ['M01.060.406'], ['M01.060.406.448'], ['C17.300'], ['C01.150.252.245', 'C01.190.249', 'C14.260.249', 'C14.280.282.407'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.0... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Looking out for family caregivers. | Nurses are regularly advised to become involved in community development initiatives, but what exactly does this entail and what are the precautions that should be considered? A 10-week, government sponsored, community-development program for family caregivers allowed nurses to offer education and support to six under-... | ['Caregivers', 'Community Health Nursing', 'Family', 'Humans', 'Social Support'] | 8,715,522 | [['M01.085', 'M01.526.485.200', 'N02.360.200'], ['H02.478.676.150', 'N02.421.143.150'], ['F01.829.263', 'I01.880.853.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.853.500.600']] | ['Named Groups [M]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Comparison of BACTEC 12B vs solid media for the recovery of Mycobacterium avium complex from blood cultures in AIDS patients. | We compared liquid (BACTEC 12B) and solid culture media for the diagnosis of Mycobacterium avian complex (MAC) bacteremia among 258 AIDS patients with a positive blood culture. Neither culture media alone had adequate sensitivity; BACTEC 12B detected growth earlier. Use of both liquid and solid media may improve the yi... | ['AIDS-Related Opportunistic Infections', 'Bacteriological Techniques', 'Culture Media', 'Evaluation Studies as Topic', 'Humans', 'Mycobacterium avium Complex', 'Mycobacterium avium-intracellulare Infection', 'Reagent Kits, Diagnostic', 'Sensitivity and Specificity'] | 9,218,919 | [['C01.221.250.875.100', 'C01.597.050', 'C01.610.684.050', 'C01.925.597.050', 'C01.925.782.815.616.400.100', 'C20.673.480.100'], ['E01.370.225.875.150', 'E05.200.875.150'], ['D27.720.470.305', 'E07.206'], ['E05.337', 'N05.715.360.335'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.510.024.962.500.720.100', 'B... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Comparison of two different approaches in the detection of intermittent cardiorespiratory coordination during night sleep. | BACKGROUND: The objective was to evaluate and to compare two completely different detection algorithms of intermittent (short-term) cardiorespiratory coordination during night sleep. The first method is based on a combination of respiratory flow and electrocardiogram recordings and determines the relative phases of R w... | ['Adult', 'Age Factors', 'Aged', 'Algorithms', 'Circadian Rhythm', 'Electrocardiography', 'Female', 'Heart Rate', 'Humans', 'Male', 'Middle Aged', 'Respiratory Physiological Phenomena', 'Sleep Stages', 'Sleep, REM'] | 12,464,159 | [['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['G17.035', 'L01.224.050'], ['G07.180.562.190'], ['E01.370.370.380.240', 'E01.370.405.240'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['G09.772'], ['F02.830.855.796', '... | ['Named Groups [M]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Analysis of the distribution of human jejunal mast cells including the relation to age, sex, height, weight, and possible allergic manifestations. | The median number of mast cells (with 95% confidence interval) in jejunal specimens from 79 individuals was 108 (93-121)/mm2 section area. The distribution was unimodal and slightly skewed to the right. No relation was found between mast cell number and sex, age, height, or weight. A history of possible allergic manife... | ['Adolescent', 'Adult', 'Age Factors', 'Aged', 'Body Height', 'Body Weight', 'Cell Count', 'Female', 'Humans', 'Hypersensitivity', 'Intestinal Mucosa', 'Jejunum', 'Male', 'Mast Cells', 'Middle Aged', 'Sex Factors'] | 3,992,170 | [['M01.060.057'], ['M01.060.116'], ['N05.715.350.075', 'N06.850.490.250'], ['M01.060.116.100'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['E01... | ['Named Groups [M]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Comparing three screening strategies for combining first- and second-trimester Down syndrome markers. | OBJECTIVE: To describe the choices and tradeoffs inherent in 3 published strategies that combine first- and second-trimester markers for Down syndrome screening.METHODS: Published marker distributions for Down syndrome and unaffected pregnancies in the first and second trimesters were combined with a maternal age distr... | ['Adult', 'Biomarkers', 'Decision Trees', 'Down Syndrome', 'Female', 'Humans', 'Pregnancy', 'Pregnancy Trimester, First', 'Pregnancy Trimester, Second', 'Prenatal Diagnosis'] | 16,449,126 | [['M01.060.116'], ['D23.101'], ['G17.162.500'], ['C10.597.606.360.220', 'C16.131.077.327', 'C16.131.260.260', 'C16.320.180.260'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['G08.686.707.408'], ['G08.686.707.490'], ['E01.370.378.630']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Different stresses, similar morphogenic responses: integrating a plethora of pathways. | Exposure of plants to mild chronic stress can cause induction of specific, stress-induced morphogenic responses (SIMRs). These responses are characterized by a blockage of cell division in the main meristematic tissues, an inhibition of elongation and a redirected outgrowth of lateral organs. Key elements in the ontoge... | ['Antioxidants', 'Cell Division', 'Ethylenes', 'Indoleacetic Acids', 'Oxidative Stress', 'Plant Cells', 'Plant Development', 'Plants', 'Reactive Oxygen Species', 'Stress, Physiological'] | 19,021,890 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D02.455.326.271.367'], ['D03.066.288', 'D03.633.100.473.404'], ['G03.673', 'G07.775.750'], ['A11.750'], ['G07.345.625', 'G15.589'], ['B01.650'], ['D01.339.431', 'D01.650.775'], ['G... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Simultaneous tracheal and oesophageal pH measurements in asthmatic patients with gastro-oesophageal reflux. | BACKGROUND: An association between asthma and gastro-oesophageal reflux is well recognised but the underlying mechanism is unclear. One suggestion is that gastric juice is aspirated into the tracheal and upper airways but detection of these events is difficult and involves radioisotopic studies. A new method of making ... | ['Asthma', 'Esophagus', 'Gastroesophageal Reflux', 'Humans', 'Hydrogen-Ion Concentration', 'Male', 'Monitoring, Physiologic', 'Trachea'] | 7,701,464 | [['C08.127.108', 'C08.381.495.108', 'C08.674.095', 'C20.543.480.680.095'], ['A03.556.875.500'], ['C06.405.117.119.500.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['E01.370.520'], ['A04.889']] | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Functional characterization of novel allelic variants of CYP2C9 recently discovered in southeast Asians. | CYP2C9 was recently resequenced in 150 Asian subjects from Singapore. Several new coding variants were reported, and these variants are now named CYP2C9*14 (R125H), CYP2C9*15 (S162X), CYP2C9*16 (T299A), CYP2C9*17 (P382S), CYP2C9*18 (D397A), and CYP2C9*19 (Q454H). The CYP2C9*18 variant also contained an I359L change pre... | ['Alleles', 'Aryl Hydrocarbon Hydroxylases', 'Catalysis', 'China', 'Cytochrome P-450 CYP2C9', 'DNA, Complementary', 'Escherichia coli', 'Genetic Variation', 'Humans', 'Hydroxylation', 'India', 'Kinetics', 'Mutagenesis, Site-Directed', 'Polymorphism, Single Nucleotide', 'Recombinant Proteins', 'Singapore', 'Tolbutamide'... | 16,099,926 | [['G05.360.340.024.340.030'], ['D08.244.453.005', 'D08.811.682.690.708.170.010', 'D12.776.422.220.453.010'], ['G02.130'], ['Z01.252.474.164'], ['D08.244.453.491.500.500', 'D08.811.682.690.708.170.450.500.500', 'D12.776.422.220.453.491.500.500'], ['D13.444.308.497.220', 'D13.444.600.223.500', 'D27.720.470.530.600.223.26... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Effects of sustained reduction of enteric methane emissions with dietary supplementation of 3-nitrooxypropanol on growth performance of growing and finishing beef cattle. | The study objective was to evaluate the effects of sustained reduction of enteric methane (CH) emissions with dietary supplementation of the inhibitor 3-nitrooxypropanol (NOP) on growth rate and feed conversion efficiency of growing and finishing beef cattle. Eighty-four crossbred steers were used in a 238-d feeding st... | ['Animal Feed', 'Animal Nutritional Physiological Phenomena', 'Animals', 'Cattle', 'Diet', 'Dietary Supplements', 'Male', 'Methane', 'Propanols'] | 27,285,700 | [['G07.203.300.300.100', 'J02.500.300.100'], ['G07.203.650.161'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G07.203.650.240'], ['G07.203.300.456', 'J02.500.456'], ['D02.455.326.146.571'], ['D02.033.755']] | ['Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Reverse Total Shoulder Arthroplasty for Posttraumatic Sequelae. | OBJECTIVES: The sequelae of proximal humeral fractures can produce severe shoulder dysfunction. We assessed the results of reverse shoulder arthroplasty (RSA) for these complex problems.DESIGN: Retrospective multicenter study.SETTING: Tertiary care referral hospitals.PATIENTS: A total of 26 patients were identified who... | ['Adult', 'Aged', 'Aged, 80 and over', 'Arthroplasty, Replacement, Shoulder', 'Female', 'Fracture Healing', 'Humans', 'Male', 'Middle Aged', 'Range of Motion, Articular', 'Recovery of Function', 'Retrospective Studies', 'Shoulder Fractures', 'Shoulder Pain', 'Shoulder Prosthesis', 'Treatment Outcome', 'United States'] | 26,270,461 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.555.110.110.299', 'E04.650.110.299', 'E04.680.101.110.299'], ['G16.762.891.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.600.700', 'G11.427.760'], ['G16.757'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
A simulator-based approach to training in aeronautical decision making. | The effectiveness of a simulator-based approach to training pilot skills in risk assessment and decision making was evaluated in a sample of pilots enrolled in a university aviation science program. The 16 experimental group subjects received 4 hours (h) of classroom instruction designed to enhance pilot judgment skill... | ['Accidents, Aviation', 'Aerospace Medicine', 'Aircraft', 'Decision Making', 'Humans', 'Risk Factors'] | 2,923,595 | [['N06.850.135.185'], ['H02.403.029'], ['J01.937.285.100'], ['F02.463.785.373'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.360.750.625.700.700', 'N06.850.490.625.750', 'N06.850.520.830.600.800.725']] | ['Health Care [N]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 |
[Prenatal diagnosis and management of fetal hepatic hemangioma]. | OBJECTIVE: To review the application of medical imaging in diagnosis and management of fetal hepatic hemangioma.METHODS: Clinical data and imaging findings of 14 cases of fetal hepatic hemangioma, who were diagnosed prenatally and followed up in Women's Hospital of Zhejiang University School of Medicine from February 2... | ['Female', 'Fetus', 'Hemangioma', 'Humans', 'Liver Neoplasms', 'Magnetic Resonance Imaging', 'Pregnancy', 'Pregnancy Outcome', 'Prenatal Diagnosis', 'Retrospective Studies'] | 31,901,050 | [['A16.378'], ['C04.557.645.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.274.623', 'C06.301.623', 'C06.552.697'], ['E01.370.350.825.500'], ['G08.686.784.769'], ['E01.789.700', 'G08.686.784.769.496'], ['E01.370.378.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.50... | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Endoscopic intraventricular surgery for treatment of hydrocephalus and loculated CSF space in children less than one year of age. | Controversy exists regarding whether children under 1 year of age have a higher risk of treatment failure after neuroendoscopic procedures for the treatment of hydrocephalus than older children. We retrospectively reviewed the surgical management and clinical outcome of 15 infants who underwent neuroendoscopic surgery ... | ['Cerebrospinal Fluid Shunts', 'Endoscopy', 'Female', 'Humans', 'Hydrocephalus', 'Infant', 'Infant, Newborn', 'Magnetic Resonance Imaging', 'Male', 'Retrospective Studies', 'Third Ventricle', 'Ventriculostomy'] | 12,006,753 | [['E04.035.188', 'E04.525.170'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.228.140.602'], ['M01.060.703'], ['M01.060.703.520'], ['E01.370.350.825.500'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', '... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Nano-Structural Effects on Gene Transfection: Large, Botryoid-Shaped Nanoparticles Enhance DNA Delivery via Macropinocytosis and Effective Dissociation. | Effective delivery is the primary barrier against the clinical translation of gene therapy. Yet there remains too much unknown in the gene delivery mechanisms, even for the most investigated polymeric carrier (i.e., PEI). As a consequence, the conflicting results have been often seen in the literature due to the large ... | ['Animals', 'Cell Line', 'DNA', 'Disease Models, Animal', 'Genetic Therapy', 'Humans', 'Mice, Nude', 'Nanoparticles', 'Neoplasm Transplantation', 'Neoplasms', 'Pinocytosis', 'Polyethyleneimine', 'Transfection', 'Treatment Outcome'] | 31,037,125 | [['B01.050'], ['A11.251.210'], ['D13.444.308'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['E02.095.301', 'E05.393.420.301'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500.550.500'], ['J01.637.512.600'], ['E05.624'], ['C04'], ['G04.417.370'], ['D02.455.326.271.665.550.6... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Development of chemiluminescence method for determination of 10-hydroxycamptothecin based on luminol-[Ag(HIO₆)₂]⁵⁻ reaction in alkaline solution. | A novel chemiluminescence (CL) method was developed for the determination of 10-hydroxycamptothecin(HCPT) based on the CL reaction between [Ag(HIO₆)₂]⁵⁻ and luminol in alkaline solution. CL emission of Ag(III) complex-luminol in alkaline medium was very different from that in acidic medium. A possible mechanism of enha... | ['Antineoplastic Agents, Phytogenic', 'Camptothecin', 'Humans', 'Limit of Detection', 'Luminescence', 'Luminescent Measurements', 'Luminol'] | 20,812,199 | [['D27.505.954.248.179'], ['D03.132.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['G01.358.500.505.650.665', 'G01.590.540.665', 'G01.750.250.650.665', 'G01.750.770.578.665'], ['E05.196.712.516'], ['D03.383.710.350']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Corticotropin-releasing hormone activates ERK1/2 MAPK in specific brain areas. | Corticotropin-releasing hormone (CRH) coordinates hormonal and behavioral responses to stress. The mitogen-activated protein kinase extracellular signal-related kinase 1/2 (ERK1/2) mediates several functions in different forebrain structures and recently has been implicated in CRH signaling in cultured cells. To study ... | ['Animals', 'Brain', 'Corticotropin-Releasing Hormone', 'Enzyme Activation', 'Hypothalamus', 'Male', 'Mice', 'Mice, Transgenic', 'Microscopy, Confocal', 'Mitogen-Activated Protein Kinase 3', 'Mitogen-Activated Protein Kinase Kinases', 'Organ Specificity', 'Prosencephalon'] | 15,833,812 | [['B01.050'], ['A08.186.211'], ['D06.472.699.327.740.140', 'D12.644.400.400.740.140', 'D12.644.548.365.740.140', 'D12.776.631.650.405.740.140'], ['G02.111.263', 'G03.328'], ['A08.186.211.180.497', 'A08.186.211.200.317.357'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.136.500', 'B01.050.150.900.649.313.9... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Web-based training in occupational medicine. | OBJECTIVES: The aim of our project was to develop and evaluate an interactive computer-based approach to teach medical students in occupational medicine. To enhance interest in occupational medicine the major focus was on clinical and practical aspects of occupational medicine.METHODS: The computer program was designed... | ['Humans', 'Internet', 'Occupational Medicine', 'Program Development', 'Program Evaluation', 'Software', 'User-Computer Interface'] | 12,592,582 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['H02.403.720.750.510'], ['N04.452.760'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['L01.224.900'], ['L01.224.900.910']] | ['Organisms [B]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
[Refining criteria for providing the body with vitamin B2]. | The following patterns should be recommended as a criterion of normal vitamin B2 requirements: the FAD-effect is no more than 1.25, the levels of riboflavin, more than 5 ng/ml in the plasma and more than 130 ng/ml in the erythrocytes. At the same time, the hourly urinary riboflavin excretion more than 10 g/h may be use... | ['Adolescent', 'Adult', 'Child', 'Erythrocytes', 'Flavin-Adenine Dinucleotide', 'Humans', 'Riboflavin'] | 7,618,301 | [['M01.060.057'], ['M01.060.116'], ['M01.060.406'], ['A11.118.290', 'A11.443.240', 'A15.145.229.334'], ['D03.633.100.733.315.650.249', 'D03.633.100.759.646.138.506', 'D03.633.300.507.650.249', 'D08.211.474.650.249', 'D13.695.667.138.506', 'D13.695.827.068.506', 'D23.767.405.650.249'], ['B01.050.150.900.649.313.988.400.... | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Differential stress protein mRNA expression during early ischaemic preconditioning in the rabbit heart and its relationship to adenosine receptor function. | The aim of this study was: (1) to elucidate in more detail the relationship between stress protein expression and brief periods of ischaemia and reperfusion, such as occur during early (classical) ischaemic preconditioning (PC) in the rabbit myocardium; (2) to determine whether stress protein expression is affected by ... | ['Adaptation, Physiological', 'Adenosine', 'Animals', 'Chaperonin 60', 'Gene Expression Regulation', 'HSP70 Heat-Shock Proteins', 'Heat-Shock Proteins', 'Hemodynamics', 'Male', 'Myocardial Ischemia', 'Myocardial Reperfusion', 'Proton-Translocating ATPases', 'Purinergic P1 Receptor Agonists', 'Purinergic P1 Receptor Ant... | 8,576,930 | [['G07.025', 'G16.012.500'], ['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['B01.050'], ['D08.811.277.040.025.142.500.500', 'D12.776.580.216.210.590.750'], ['G05.308'], ['D12.776.580.216.375'], ['D12.776.580.216'], ['G09.330.380'], ['C14.280.647', 'C14.907.585'], ['E04.100.700.600', 'E05.680.730.60... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Citalopram (Seropram) in tablet and infusion forms in the treatment of major depression]. | Citalopram i.v. and oral had a reliable antidepressive and anxiolytic effect in 101 hospitalized patients, as apparent from the achievement of complete remission in cca 60% of the patients with major depression after four weeks follow-up. Treatment with citalopram by the intravenous or oral route was most successful in... | ['Citalopram', 'Depressive Disorder', 'Female', 'Humans', 'Infusions, Intravenous', 'Male', 'Middle Aged', 'Tablets'] | 8,124,733 | [['D02.092.831.170', 'D02.626.320', 'D03.633.100.127.187'], ['F03.600.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['M01.060.116.630'], ['D26.255.830']] | ['Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Completion of the amino acid sequence of the C-terminal half of the porcine estradiol receptor by Edman degradation: reconfirmation of the absence of O-linked sugars and phosphates. | The peptide A569-Y582 of the porcine estradiol receptor containing the missing sequence T570-M581 (1) was isolated and sequenced. The 4 seryl- and 2 threonyl-PTH amino acids were recovered in normal yields, excluding their posttranslational modification and reconfirming the absence of O-glycosylation and O-phosphorylat... | ['Amino Acid Sequence', 'Animals', 'Carbohydrates', 'Chromatography, Affinity', 'Female', 'Molecular Sequence Data', 'Peptide Fragments', 'Peptide Mapping', 'Phosphates', 'Receptors, Estradiol', 'Sexual Maturation', 'Swine', 'Uterus'] | 8,619,812 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['D09'], ['E05.196.181.400.170'], ['L01.453.245.667'], ['D12.644.541'], ['E05.196.181.400.454.720', 'E05.196.401.319.720', 'E05.196.700', 'E05.393.760.705.685'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D01.695.625.675.650'], ['D12.776.826.750.350.350... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Intrapartum electronic fetal heart rate monitoring versus intermittent auscultation: a meta-analysis. | OBJECTIVE: To use a meta-analysis of all published randomized trials to determine whether the use of continuous electronic fetal heart rate monitoring (EFM) as the main method of intrapartum fetal surveillance is associated with improved pregnancy outcome compared to intermittent auscultation.DATA SOURCES: We used the ... | ['Cardiotocography', 'Confidence Intervals', 'Delivery, Obstetric', 'Electronics, Medical', 'Female', 'Fetal Distress', 'Fetal Heart', 'Fetal Hypoxia', 'Heart Auscultation', 'Heart Rate, Fetal', 'Humans', 'Odds Ratio', 'Predictive Value of Tests', 'Pregnancy', 'Pregnancy Outcome', 'Randomized Controlled Trials as Topic... | 7,800,313 | [['E01.370.370.380.170', 'E01.370.378.230.150', 'E01.370.520.230.150'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['E04.520.252'], ['H01.671.293.319'], ['C23.888.380'], ['A07.541.278', 'A16.378.303'], ['C13.703.277.390', 'C16.300.420', 'C23.888.852.079.594'], ['E01.370.370.380.400', 'E01.370.60... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Disciplines and Occupations [H]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Diabetogenic effects of salmon calcitonin are attributable to amylin-like activity. | During the development of synthetic calcitonins for therapeutic use in bone disease, a "diabetogenic" (hyperglycemic) effect was observed, particularly with salmon calcitonin. The effect was attributed by some to inhibition of insulin secretion. We have recently reported high-affinity (28 pmol/L) amylin-binding sites i... | ['Amino Acid Sequence', 'Amyloid', 'Animals', 'Blood Glucose', 'Calcitonin', 'Diabetes Mellitus, Experimental', 'Dose-Response Relationship, Drug', 'Drug Synergism', 'Glucagon', 'Glycogen', 'Hindlimb', 'Injections, Intravenous', 'Insulin', 'Insulin Secretion', 'Islet Amyloid Polypeptide', 'Lactates', 'Lactic Acid', 'Ma... | 8,786,728 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D05.500.049', 'D12.776.049'], ['B01.050'], ['D09.947.875.359.448.500'], ['D06.472.699.150', 'D06.472.931.052', 'D12.644.400.095', 'D12.644.548.150', 'D12.776.631.650.095'], ['C18.452.394.750.074', 'C19.246.240', 'E05.598.500.374'], ['G07.690.773.875', 'G07.690.936.500'], [... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Preschool negative emotionality predicts activity and connectivity of the fusiform face area and amygdala in later childhood. | Negative emotionality (NE) refers to individual differences in the propensity to experience and react with negative emotions and is associated with increased risk of psychological disorder. However, research on the neural bases of NE has focused almost exclusively on amygdala activity during emotional face processing. ... | ['Adolescent', 'Aging', 'Amygdala', 'Child', 'Child, Preschool', 'Depression', 'Face', 'Female', 'Humans', 'Infant', 'Longitudinal Studies', 'Magnetic Resonance Imaging', 'Male', 'Nerve Net', 'Temperament', 'Temporal Lobe'] | 28,992,271 | [['M01.060.057'], ['G07.345.124'], ['A08.186.211.180.090', 'A08.186.211.200.885.287.249.152'], ['M01.060.406'], ['M01.060.406.448'], ['F01.145.126.350'], ['A01.456.505'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['E05.318.372.500.750.500', 'N05.715.360.330.500.750.500', 'N06.850.520.450.500.750... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
A comparison of immunologic profiles and their influence on bacteremia in surgical patients with a high risk of infection. | Prospective sequential studies of the antibacterial function of neutrophils, lymphocyte responsiveness, opsonic capacity of serum and serum levels of C3(B), properdin, factor B, IgG, and albumin were made in 32 patients with severe burn injury (greater than or equal to 45%), 21 patients with severe multisystem traumati... | ['Adolescent', 'Adult', 'Aged', 'Bacterial Infections', 'Burns', 'Child', 'Child, Preschool', 'Complement C3b', 'Complement Factor B', 'Humans', 'Immunologic Techniques', 'Immunosuppression', 'Kidney Transplantation', 'Middle Aged', 'Neutrophils', 'Opsonin Proteins', 'Prospective Studies', 'Risk', 'Sepsis', 'Transplant... | 377,544 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Expression of the gamma 2 chain of laminin-332 in eutopic and ectopic endometrium of patients with endometriosis. | BACKGROUND: Endometrial cells, which are shed by retrograde menstruation, may aberrantly express molecules involved in invasion and migration, leading to endometriosis. The aim of this study was to investigate the expression of the laminin gamma 2 chain (LAMC2) in the tissues of women with and without endometriosis.MET... | ['Endometriosis', 'Endometrium', 'Female', 'Humans', 'Immunohistochemistry', 'Laminin', 'RNA, Messenger', 'Reverse Transcriptase Polymerase Chain Reaction'] | 24,070,183 | [['C13.351.500.163'], ['A05.360.319.679.490'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122... | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Insulin increases cell numbers and morphological development in mouse pre-implantation embryos in vitro. | Insulin, alone or in combination with bovine serum albumin (BSA), was investigated for its effects on cell proliferation and on the proportions of mouse pre-implantation embryos reaching compaction and forming blastocysts during culture in a common basal medium in vitro. Insulin promoted cleavage by 16-20% when added t... | ['Animals', 'Blastocyst', 'Cell Count', 'Embryonic and Fetal Development', 'In Vitro Techniques', 'Insulin', 'Mice', 'Mitotic Index', 'Serum Albumin, Bovine'] | 1,957,017 | [['B01.050'], ['A16.254.500'], ['E01.370.225.500.195', 'E05.200.500.195', 'E05.242.195', 'G04.140'], ['G07.345.500.325', 'G08.686.784.170'], ['E05.481'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['B01.050.150.900.649.313.992.635.505.500'], ['E01.370.225.500.385.500', 'E05.200.500.385.500', 'E05.2... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Use of cefoperazone MacConkey agar for selective isolation of Laribacter hongkongensis. | A new selective medium, cefoperazone MacConkey agar (CMA), was developed for primary isolation of Laribacter hongkongensis from stool. Its performance in quantitative recovery and in a clinical evaluation of 4,741 human diarrheal stool specimens was superior to that of charcoal cefoperazone deoxycholate agar. In additi... | ['Agar', 'Anti-Bacterial Agents', 'Bacteriological Techniques', 'Cefoperazone', 'Culture Media', 'Diarrhea', 'Feces', 'Gram-Negative Bacterial Infections', 'Humans', 'Microbial Sensitivity Tests', 'Neisseriaceae'] | 14,532,237 | [['D09.698.360.041'], ['D27.505.954.122.085'], ['E01.370.225.875.150', 'E05.200.875.150'], ['D02.065.589.099.249.150.160', 'D02.886.665.074.150.160', 'D03.633.100.300.249.150.160'], ['D27.720.470.305', 'E07.206'], ['C23.888.821.214'], ['A12.459'], ['C01.150.252.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
In vitro 5-lipoxygenase and anti-oxidant activities of South African medicinal plants commonly used topically for skin diseases. | An investigation was undertaken to determine the possible mechanisms of action of medicinal plants used for dermatological pathologies. A total of 14 plant species were selected from the readily available ethnobotanical literature. 5-Lipoxygenase and DPPH (2,2-diphenyl-1-picrylhydrazyl) assays were used to determine th... | ['Administration, Cutaneous', 'Administration, Topical', 'Antioxidants', 'Arachidonate 5-Lipoxygenase', 'Biphenyl Compounds', 'Chemical Phenomena', 'Chemistry, Physical', 'Dermatologic Agents', 'Free Radical Scavengers', 'Humans', 'Lipid Bilayers', 'Lipoxygenase Inhibitors', 'Medicine, African Traditional', 'Picrates',... | 16,931,900 | [['E02.319.267.120.060'], ['E02.319.267.120'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D08.811.682.690.416.583.500.055', 'D12.776.556.579.374.568.500.020'], ['D02.455.426.559.389.185'], ['G02'], ['H01.181.529'], ['D27.505.954.444'], ['D27.505.519.217.500'], ['B01.050.150.900.649.313.988.400.112... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Diseases [C]... | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 |
Differences in thigh muscularity and dynamic torque between junior and senior soccer players. | The aim of the present study was to examine differences in thigh muscularity and dynamic torque between elite junior (15.7 +/- 0.2 years) and senior (22.6 +/- 2.4 years) soccer players. Cross-sectional areas of the total muscle compartment, quadriceps femoris, and hamstrings + adductors were determined using magnetic r... | ['Adolescent', 'Adult', 'Biomechanical Phenomena', 'Body Weights and Measures', 'Humans', 'Male', 'Muscle Strength', 'Quadriceps Muscle', 'Soccer', 'Thigh', 'Young Adult'] | 19,031,332 | [['M01.060.057'], ['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['E01.370.600.115.100', 'E05.041.124', 'G07.100.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.600.425', 'G11.427.560'], ['A02.633.567.850'], ['I03.450.642.845.800'], ['A01.378.610.750'], ['M01.060.116.815']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
[ESC and AHA guidelines 2015 on endocarditis : In competition or synchrony?] | In the 2015 guidelines of the European Society of Cardiology (ESC) and the American Heart Association (AHA) on infective endocarditis, the diagnostics are based on the modified Duke criteria. The diagnosis can be confirmed by a combination of micro-organisms demonstrated in culture or in situ, with the detection of val... | ['Cardiology', 'Diagnostic Techniques, Cardiovascular', 'Endocarditis', 'Europe', 'Evidence-Based Medicine', 'Guideline Adherence', 'Humans', 'Practice Guidelines as Topic', 'United States'] | 27,822,623 | [['H02.403.429.163'], ['E01.370.370'], ['C14.280.282'], ['Z01.542'], ['H02.249.750', 'H02.403.200.400'], ['N04.761.337', 'N05.715.360.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N04.761.700.350.650', 'N05.700.350.650'], ['Z01.107.567.875']] | ['Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Geographicals [Z]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 |
Retrospective assessment of ADHD symptoms in childhood: discriminatory validity of Finnish translation of the Wender Utah Rating Scale. | OBJECTIVE: To examine the discriminatory validity of the Wender Utah Rating Scale (WURS) and its five suggested subscales (Conduct Problems, Impulsivity Problems, Mood Difficulties, Inattention/Anxiety, Academic Concerns) in a Finnish sample.METHOD: WURS was administered to 114 adults, aged 18 to 55 years. Participants... | ['Adolescent', 'Adult', 'Attention Deficit Disorder with Hyperactivity', 'Female', 'Finland', 'Humans', 'Male', 'Middle Aged', 'Predictive Value of Tests', 'Psychiatric Status Rating Scales', 'Psychometrics', 'Reproducibility of Results', 'Retrospective Studies', 'Translations'] | 22,286,113 | [['M01.060.057'], ['M01.060.116'], ['F03.625.094.150'], ['Z01.542.816.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.370.800.650', 'N05.715.360.325.700.640', 'N06.850.520.445.800.650'], ['F04.711.513.653'], ['F04.711.780'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685'... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Repair of idiopathic dilatation of the right atrium. | Idiopathic dilatation of the right atrium is a rare cardiac anomaly. The surgical management of this rare cardiac anomaly is reviewed. | ['Cardiac Surgical Procedures', 'Diagnostic Imaging', 'Dilatation, Pathologic', 'Female', 'Follow-Up Studies', 'Heart Atria', 'Heart Defects, Congenital', 'Humans', 'Middle Aged', 'Pericardium', 'Time Factors', 'Treatment Outcome'] | 24,433,219 | [['E04.100.376', 'E04.928.220'], ['E01.370.350'], ['C23.300.325'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['A07.541.358'], ['C14.240.400', 'C14.280.400', 'C16.131.240.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A07.541.795', 'A10.615... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Effects of electromagnetic noise on the enhancement of stress-activated protein kinase(SAPK) phosphorylation induced by 50 Hz magnetic fields]. | OBJECTIVE: To investigate the possible interference effect of electromagnetic noise exposure on phosphorylation of stress-activated protein kinase(SAPK) induced by 50 Hz magnetic field(MF).METHODS: Chinese hamster lung(CHL) cells were exposed to sham exposure(C), 0.4 mT 50 Hz sinusoidal MF, 0.4 mT electromagnetic noise... | ['Animals', 'Cell Line', 'Cricetinae', 'Cricetulus', 'Electromagnetic Fields', 'Mitogen-Activated Protein Kinases', 'Noise', 'Phosphorylation'] | 14,694,644 | [['B01.050'], ['A11.251.210'], ['B01.050.150.900.649.313.992.635.075.250'], ['B01.050.150.900.649.313.992.635.075.250.250'], ['G01.358.500.260', 'G01.358.750.500'], ['D08.811.913.696.620.682.700.567', 'D12.644.360.450', 'D12.776.476.450'], ['G01.750.770.776.567', 'G16.500.275.600', 'N06.230.400', 'N06.850.460.610'], ['... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Creation of an Acellular Vaginal Matrix for Potential Vaginal Augmentation and Cloacal Repair. | STUDY OBJECTIVE: Our aim was to use porcine vagina to create a vaginal matrix and test its cellular biocompatibility.DESIGN, SETTING, AND PARTICIPANTS: Vagina was harvested from pigs and decellularized (DC) using a combination of detergents (Triton X-100 and sodium deoxycholate) and enzymes (DNAse/RNAse).INTERVENTIONS:... | ['Animals', 'Cloaca', 'Epithelial Cells', 'Extracellular Matrix', 'Female', 'Immunohistochemistry', 'Materials Testing', 'Mesenchymal Stem Cells', 'Swine', 'Tissue Engineering', 'Tissue Scaffolds', 'Vagina'] | 29,792,924 | [['B01.050'], ['A13.223', 'A16.178'], ['A11.436'], ['A11.284.295.310'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.122.573.512', 'H01.181.122.605.512'], ['E05.570'],... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Combined mechanical mitral valve replacement and transmitral myectomy for hypertrophic obstructive cardiomyopathy treatment: An experience of over 20 years. | BACKGROUND: Although transaortic septal myectomy (TASM) is recognized as a standard procedure for treating hypertrophic obstructive cardiomyopathy (HOCM), occasionally the left ventricle (LV) intracavitary gradient remains postoperatively because of this technically demanding procedure. Mitral valve replacement (MVR) i... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Cardiac Surgical Procedures', 'Cardiomyopathy, Hypertrophic', 'Combined Modality Therapy', 'Echocardiography', 'Female', 'Heart Valve Prosthesis Implantation', 'Heart Ventricles', 'Humans', 'Male', 'Middle Aged', 'Mitral Valve', 'Postoperative Period', 'Treatment Ou... | 30,583,989 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E04.100.376', 'E04.928.220'], ['C14.280.238.100', 'C14.280.484.048.750.070.160'], ['E02.186'], ['E01.370.350.130.750', 'E01.370.350.850.220', 'E01.370.370.380.220'], ['E04.100.376.485', 'E04.650.410', 'E04.928.220.410'], ['A07.541.560'],... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
B(C6 | An efficient method for the coupling of N-alkylamines with silicon enolates to generate â-amino carbonyl compounds is disclosed. These reactions proceed by activation of á-amino C-H bonds by B(C6F5)3, which likely generates a "frustrated" acid/base complex in the presence of large N-alkylamines. The transformation requ... | ['Acrylamide', 'Amines', 'Boranes', 'Catalysis', 'Hydrocarbons, Fluorinated', 'Molecular Structure', 'Oxidants', 'Silicon'] | 30,693,779 | [['D02.065.122.015', 'D02.241.081.069.094.015'], ['D02.092'], ['D01.132.105', 'D02.203.087'], ['G02.130'], ['D02.455.526.510'], ['G02.111.570', 'G02.466'], ['D27.720.642', 'D27.888.569.540'], ['D01.268.513.937']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Infertility in a Maltese poodle as a result of a sperm midpiece defect. | A 2 1/2-year-old Maltese poodle was examined for breeding soundness following a series of unsuccessful matings to fertile bitches. He was found to have only 8% normal sperm in his ejaculate when Spermac-stained smears were examined under the light microscope. The defect most frequently encountered involved the midpiece... | ['Animals', 'Dog Diseases', 'Dogs', 'Infertility, Male', 'Male', 'Sperm Head', 'Spermatozoa'] | 4,020,810 | [['B01.050'], ['C22.268'], ['B01.050.150.900.649.313.750.250.216.200'], ['C12.294.365.700'], ['A05.360.490.890.820', 'A11.497.760.400'], ['A05.360.490.890', 'A11.497.760']] | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Clinically anatomic study on the relation between the form of pleural cupula and its surrounding commonly-used acupoints]. | OBJECTIVE: To explore the relation of the form of pleural cupula of the normal adult with safety of acupuncture at commonly-used acupoints around the pleural cupula.METHODS: The safe depth for the commonly-used acupoints around the pleural cupula and the relation with the form of pleural cupula were investigated in 46 ... | ['Acupuncture Points', 'Adult', 'Female', 'Humans', 'Male', 'Pleura'] | 16,739,850 | [['E02.190.044.555.035'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.716', 'A10.615.789.736']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Evaluation of data on live birth certificates from the Information System on Live Births (SINASC) in Campinas, S?o Paulo, 2009]. | OBJECTIVE: To assess the completeness and reliability of the Information System on Live Births (Sinasc) data.METHODS: A cross-sectional analysis of the reliability and completeness of Sinasc's data was performed using a sample of Live Birth Certificate (LBC) from 2009, related to births from Campinas, Southeast Brazil.... | ['Birth Certificates', 'Brazil', 'Cross-Sectional Studies', 'Databases as Topic', 'Humans', 'Infant, Newborn', 'Information Systems', 'Live Birth'] | 25,479,847 | [['E05.318.308.940.250', 'L01.399.250.900.250', 'N04.452.859.132', 'N05.715.360.300.715.175', 'N06.850.520.308.940.250'], ['Z01.107.757.176'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['L01.313.500.750.300.188', 'L01.470.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 |
Blastocystis hominis: neutral red supravital staining and its application to in vitro drug sensitivity testing. | A simple in vitro drug sensitivity testing system for Blastocystis hominis clinical isolates was developed. Application of supravital staining by neutral red allowed quantitative viability assessment. Four xenic cultures, isolated from human sources, were grown in modified monophasic Robinson's medium and tested for se... | ['Amebicides', 'Animals', 'Blastocystis hominis', 'Chloroquine', 'Coloring Agents', 'Humans', 'Metronidazole', 'Neutral Red', 'Parasitic Sensitivity Tests', 'Paromomycin', 'Quinacrine', 'Staining and Labeling', 'Sulfamethoxazole', 'Tetracycline', 'Thiazoles', 'Trimethoprim'] | 10,935,909 | [['D27.505.954.122.250.100.055'], ['B01.050'], ['B01.046.500.100.200.200.375'], ['D03.633.100.810.050.180'], ['D27.720.233'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D02.640.672.500', 'D03.383.129.308.658.500'], ['D03.633.300.704.600'], ['E01.370.225.940', 'E05.200.940', 'E05.337.550.700'], ['D09.408.051.706... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A randomized prospective study of the cost-effectiveness of the conventional spike, O-set, and UVXD techniques in continuous ambulatory peritoneal dialysis. | OBJECTIVE: To compare the clinical outcome and cost-effectiveness of three techniques for continuous ambulatory peritoneal dialysis (CAPD): the conventional spike technique (C), the O-set (O), and UVXD (U, ultraviolet irradiation connection box).DESIGN: A randomized and prospective comparison of three CAPD techniques.S... | ['Adolescent', 'Adult', 'Bacterial Infections', 'Catheterization', 'Child', 'Cost-Benefit Analysis', 'Costs and Cost Analysis', 'Female', 'Humans', 'Male', 'Middle Aged', 'Outcome Assessment, Health Care', 'Peritoneal Dialysis, Continuous Ambulatory', 'Peritonitis', 'Prospective Studies'] | 7,948,238 | [['M01.060.057'], ['M01.060.116'], ['C01.150.252'], ['E02.148', 'E05.157'], ['M01.060.406'], ['N03.219.151.125'], ['N03.219.151'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['H01.770.644.145.431', 'N04.761.559.590', 'N05.715.360.575.575'], ['E02.760.106.500', 'E02.870.300.650.500', 'E02.912.... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
[Structural similarity of regions of activation cleavage of protein-precursors by reactive centers of serpins]. | A comparative analysis of primary sequences of the region of "leaving group" of a number of splittings evoked by serine proteinases under the activation of protein-precursors has been carried out. A pronounced domination of amino acids of hydrophobic nature in P2'-position similar to that observed in case of the reacti... | ['Amino Acid Sequence', 'Amino Acids', 'Binding Sites', 'Hydrolysis', 'Molecular Sequence Data', 'Molecular Structure', 'Protein Precursors', 'Serpins', 'Solubility', 'Water'] | 8,830,432 | [['G02.111.570.060', 'L01.453.245.667.060'], ['D12.125'], ['G02.111.570.120'], ['G02.380'], ['L01.453.245.667'], ['G02.111.570', 'G02.466'], ['D12.776.811'], ['D12.644.861', 'D12.776.872', 'D27.505.519.389.745.800.675'], ['G02.805'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[The combined effect of hyperthermia and irradiation on cultured human glioma cell line]. | The effects of hyperthermia (HT) and irradiation (RT) on a cultured human glioma cell line (KC) was examined by a colony formation assay and immuno-histochemical methods using monoclonal antibody (MoAb) against bromodeoxyuridine (BrdU) and MoAb Ki-67. The colony formation assay revealed that HT inhibited the cell survi... | ['Antigens, Neoplasm', 'Bromodeoxyuridine', 'Combined Modality Therapy', 'Glioma', 'Humans', 'Hyperthermia, Induced', 'Immunohistochemistry', 'Male', 'Proliferating Cell Nuclear Antigen', 'Radiotherapy', 'Tumor Cells, Cultured'] | 8,797,206 | [['D23.050.285'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.300.150'], ['E02.186'], ['C04.557.465.625.600.380', 'C04.557.470.670.380', 'C04.557.580.625.600.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.565'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.5... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Elafibranor Inhibits Chronic Kidney Disease Progression in NASH Mice. | Identification of new pharmacological approaches to inhibit the excessive fat intake-induced steatohepatitis and chronic kidney disease (CKD) is important. High-fat diet (HFD)-induced steatohepatitis and CKD share common pathogenesis involving peroxisome proliferator-activated receptor (PPAR)-á and -ä. Elafibranor, a d... | ['Animals', 'Apoptosis', 'Beclin-1', 'Chalcones', 'Diet, High-Fat', 'Disease Models, Animal', 'Disease Progression', 'Enzyme Inhibitors', 'Gene Expression Regulation', 'Humans', 'Kidney', 'Mice', 'Microtubule-Associated Proteins', 'Oxidative Stress', 'PPAR alpha', 'PPAR delta', 'Podocytes', 'Propionates', 'Renal Insuff... | 31,321,239 | [['B01.050'], ['G04.146.954.035'], ['D12.644.360.075.335', 'D12.776.094.500', 'D12.776.476.075.335'], ['D02.522.818.222', 'D03.383.663.283.266.450.221', 'D03.633.100.150.266.450.221'], ['G07.203.650.240.267'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.550.291.656'], ['D27.505.519.389'], ['G05.308'], ['B01.05... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Impact of methicillin resistance on clinical features and outcomes of infective endocarditis due to Staphylococcus aureus. | BACKGROUND: This study sought to determine the impact of methicillin resistance on clinical features and outcomes in patients with Staphylococcus aureus (SA) infective endocarditis (IE).METHODS: Retrospective chart review. Univariate and forward stepwise logistic regressions were conducted to determine which factors si... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Child', 'Child, Preschool', 'Endocarditis, Bacterial', 'Female', 'Heart Diseases', 'Humans', 'Infant', 'Male', 'Methicillin Resistance', 'Middle Aged', 'Odds Ratio', 'Retrospective Studies', 'Staphylococcal Infections', 'Survival Analysis', 'Treatment Outcome'] | 15,367,872 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406'], ['M01.060.406.448'], ['C01.150.252.245', 'C01.190.249', 'C14.260.249', 'C14.280.282.407'], ['C14.280'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['G06.099.225.500.600.525', 'G06.225.347.500.600.525... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Clinical evaluation of cefozopran for infections associated with hematological malignancies]. | Cefozopran (CZOP) was used as an initial antibacterial therapy for infections in patients with hematological malignancies. CZOP was given at a daily dose of 4 g by drip intravenously to patients who were febrile over 38 degrees C and were suspected as having bacterial infections. As underlying diseases, 8 patients had ... | ['Acute Disease', 'Adult', 'Aged', 'Aged, 80 and over', 'Anemia, Aplastic', 'Bacterial Infections', 'Bronchitis', 'Cephalosporins', 'Female', 'Granulocytes', 'Hodgkin Disease', 'Humans', 'Leukemia', 'Leukemia, Myeloid, Acute', 'Leukemia, T-Cell', 'Leukocyte Count', 'Lymphoma', 'Male', 'Middle Aged', 'Multiple Myeloma',... | 9,836,122 | [['C23.550.291.125'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C15.378.071.085', 'C15.378.190.223.250'], ['C01.150.252'], ['C01.748.099', 'C08.127.446', 'C08.381.495.146', 'C08.730.099'], ['D02.065.589.099.249', 'D02.886.665.074', 'D03.633.100.300.249'], ['A11.118.637.415', 'A11.148.350', 'A11.6... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hydroxylation of 3-acetyl-2-(2,6-dimethyl-5-heptenyl)oxazolidine by rat liver microsomes. Identification of some isomeric metabolites. | The metabolism of nonradiolabeled, stereoisomeric mixtures of 3-acetyl-2-(2,6-dimethyl-5-heptenyl)oxazolidine (I), a new citronelial-based insect repellent, by induced and uninduced rat liver microsomes has been examined in a NADPH-generating system at a substrate concentration of 1.67 mM. By comparison of retention ti... | ['Alcohols', 'Animals', 'Chromatography, Gas', 'Hydroxylation', 'In Vitro Techniques', 'Insect Repellents', 'Male', 'Microsomes, Liver', 'Oxazoles', 'Rats', 'Rats, Inbred Strains', 'Stereoisomerism'] | 6,138,223 | [['D02.033'], ['B01.050'], ['E05.196.181.349'], ['G02.111.385', 'G02.607.348', 'G03.425'], ['E05.481'], ['D27.505.696.706.434', 'D27.720.031.700.441', 'D27.888.723.441'], ['A11.284.835.540.541'], ['D03.383.129.462'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Transcriptome Analysis Reveals Silver Nanoparticle-Decorated Quercetin Antibacterial Molecular Mechanism. | Facile and simple method is developed to synthesize silver-nanoparticle-decorated quercetin nanoparticles (QA NPs). Modification suggests that synergistic quercetin (Qe) improves the antibacterial effect of silver nanoparticles (Ag NPs). Characterization experiment indicates that QA NPs have a diameter of approximately... | ['Anti-Bacterial Agents', 'Escherichia coli', 'Gene Expression Profiling', 'Metal Nanoparticles', 'Quercetin', 'Silver', 'Staphylococcus aureus'] | 28,240,544 | [['D27.505.954.122.085'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['E05.393.332'], ['J01.637.512.600.500'], ['D03.383.663.283.266.450.284.777', 'D03.633.100.150.266.450.284.777'], ['D01.268.556.812', 'D01.268.956.843', 'D01.552.544.812'], ['B03.300.390.400.800.750.100', 'B03.353.500.750.750.100', 'B03.5... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
The impact of realigning a tertiary psychiatric hospital in British Columbia on other institutional sectors. | OBJECTIVE: Deinstitutionalization is an ongoing process, as many jurisdictions continue to struggle with redesigning their psychiatric systems. Historically, reducing psychiatric beds and closing hospitals have resulted in deleterious outcomes for people with severe and persistent mental illness. More recent evidence s... | ['Adult', 'Aged', 'Ambulatory Care', 'British Columbia', 'Criminal Law', 'Female', 'Health Care Reform', 'Health Services', 'Hospitals, General', 'Hospitals, Psychiatric', 'Humans', 'Length of Stay', 'Male', 'Mental Disorders', 'Middle Aged', 'Patient Discharge', 'Young Adult'] | 21,285,099 | [['M01.060.116'], ['M01.060.116.100'], ['E02.760.106', 'N02.421.585.106'], ['Z01.107.567.176.160'], ['I01.198.290', 'I01.880.604.583.100'], ['I01.655.500.608.400.285', 'I01.880.604.825.608.400.285', 'N03.349.285', 'N03.623.500.608.428.285', 'N04.590.374.285', 'N05.300.380'], ['N02.421'], ['N02.278.421.389'], ['N02.278.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Neuromonitoring of the external branch of the superior laryngeal nerve during minimally invasive thyroid surgery under local anesthesia: a prospective study of 10 patients. | OBJECTIVES/HYPOTHESIS: Avoiding alterations of the voice is a challenge in thyroid surgery. Identification and preservation of the external branch of the superior laryngeal nerve (EBSLN) is paramount for normal vocal function preservation after thyroidectomy. Conventional nerve monitoring requires a general anesthesia ... | ['Adult', 'Anesthesia, Local', 'Female', 'Follow-Up Studies', 'Humans', 'Laryngeal Nerves', 'Laryngoscopy', 'Middle Aged', 'Monitoring, Intraoperative', 'Prospective Studies', 'Thyroid Diseases', 'Thyroidectomy', 'Treatment Outcome', 'Vocal Cords', 'Voice Quality'] | 19,160,384 | [['M01.060.116'], ['E03.155.086.231'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.050.050.925.450', 'A08.800.050.600.825.450', 'A08.800.800.060.920.450', 'A08.800.800.120.900.450'], ['E01.370.386.460', 'E01.370.38... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Study of the morphology and biomechanics of sacral fracture. | OBJECTIVE: To observe the morphological characteristics of sacral fracture under different impact loads.METHOD: Ten fresh pelvic specimens were loaded in dynamic or static state. A series of mechanical parameters including the pressure strain and velocity were recorded. Morphological characteristics were observed under... | ['Biomechanical Phenomena', 'Humans', 'Male', 'Microscopy, Electron, Scanning', 'Sacrum', 'Spinal Fractures', 'Spinal Nerve Roots'] | 17,026,856 | [['G01.154.090', 'G01.374.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['A02.835.232.834.717'], ['C26.117.500.500', 'C26.404.812'], ['A08.800.800.720.725']] | ['Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association of systemic-onset juvenile idiopathic arthritis and celiac disease - a case report. | INTRODUCTION: In a 28-year period, 5508 patients were followed at our Paediatric Rheumatology Division and 712 (13%) patients had juvenile idiopathic arthritis (JIA) (ILAR criteria). One (0.14%) of them had association with celiac disease (CD), with predominance of gastrointestinal manifestations and this case was desc... | ['Arthritis, Juvenile', 'Celiac Disease', 'Child', 'Female', 'Humans'] | 22,472,933 | [['C05.550.114.122', 'C05.799.056', 'C17.300.775.049', 'C20.111.198'], ['C06.405.469.637.250', 'C18.452.603.250'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Propagation of intercellular calcium waves in PC12 cells overexpressing a carboxy-terminal fragment of amyloid precursor protein. | We have recently found that PC12 cells overexpressing a C-terminal 97 amino acid fragment containing the beta/A4 amyloid peptide of amyloid precursor protein (APP) exhibit an induced production of the gap junctional protein connexin43 (Cx43) and an induction of gap junctional communication as assessed by dye-transfer. ... | ['Amyloid beta-Protein Precursor', 'Animals', 'Calcium', 'Cell Communication', 'Connexin 43', 'Fura-2', 'Gap Junctions', 'Image Cytometry', 'Neurons', 'PC12 Cells', 'Rats', 'Signal Transduction', 'Transfection'] | 8,584,217 | [['D12.776.049.407.249', 'D12.776.543.039', 'D12.776.645.468.500', 'D12.776.811.050'], ['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G04.085'], ['D12.776.543.585.250.200'], ['D03.383.129.462.285', 'D03.633.100.127.250'], ['A11.284.149.165.420.471'], ['E01.370.225.500.386.400', 'E05.196.712.516.6... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Turning Perspective in Photoelectrocatalytic Cells for Solar Fuels. | The development of new devices for the use and storage of solar energy is a key step to enable a new sustainable energy scenario. The route for direct solar-to-chemical energy transformation, especially to produce liquid fuels, represents a necessary element to realize transition from the actual energy infrastructure. ... | ['Cost-Benefit Analysis', 'Electrochemical Techniques', 'Photochemical Processes', 'Solar Energy', 'Temperature'] | 26,663,767 | [['N03.219.151.125'], ['E05.301'], ['G02.740'], ['G01.750.897', 'N06.230.132.644.500'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Can rats learn to associate a flavour with the delayed delivery of food? | Associations between a specific flavour and access to food were studied using a discrimination procedure devised by Holman (1975). This involved giving rats one flavour (e.g. cinnamon) of saccharin solution on some days, and following this by delivery of food, and a second flavour (e.g. wintergreen) on other days which... | ['Animals', 'Appetite', 'Association Learning', 'Cues', 'Energy Intake', 'Learning', 'Male', 'Rats', 'Rats, Inbred Strains', 'Reinforcement, Psychology', 'Taste'] | 3,963,797 | [['B01.050'], ['F02.830.071', 'G07.203.650.390.070', 'G10.261.390.070'], ['F02.463.425.069.296'], ['F02.463.425.234'], ['G07.203.650.240.340'], ['F02.463.425', 'F02.784.629.529'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['F02.463.425.770']... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diagnosis of active tuberculosis by immunological methods. 2. Qualitative differences in the dermal response to tuberculin in patients with active pulmonary disease and healthy tuberculin-positive individuals. | The tuberculin reactivity of 107 patients with active pulmonary tuberculosis and 143 healthy age-matched control subjects were compared. At 48 hours 96% of patients and 76% of control subjects were positive reactors. The diameters of the reactions were of similar size. At 24 hours 93% of patients and 65% of controls we... | ['Antibodies, Bacterial', 'Humans', 'Mycobacterium tuberculosis', 'Time Factors', 'Tuberculin Test', 'Tuberculosis, Pulmonary'] | 6,820,737 | [['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.510.024.962.500.702', 'B03.510.460.400.410.552.552.702'], ['G01.910.857'], ['E01.370.225.812.871.800', 'E05.200.812.871.800', 'E05.478.594.890.800'], ['C01.150.252.410.0... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genetic markers of resistance to pyrimethamine and sulfonamides in Plasmodium falciparum parasites compared with the resistance patterns in isolates of Escherichia coli from the same children in Guinea-Bissau. | The antifolate drugs sulphadoxine and pyrimethamine are used for treatment of chloroquine-resistant Plasmodium falciparum in Africa. Resistance to pyrimethamine has been associated with point mutations in the dhfr-gene and resistance to sulphadoxine with mutations in the dhps-gene. There is concern that the use of the ... | ['Adolescent', 'Animals', 'Antimalarials', 'Child', 'Child, Preschool', 'Drug Combinations', 'Drug Resistance', 'Escherichia coli', 'Escherichia coli Infections', 'Female', 'Genetic Markers', 'Guinea-Bissau', 'Humans', 'Infant', 'Malaria, Falciparum', 'Male', 'Mutation', 'Plasmodium falciparum', 'Pyrimethamine', 'Sulfa... | 14,728,622 | [['M01.060.057'], ['B01.050'], ['D27.505.954.122.250.100.085'], ['M01.060.406'], ['M01.060.406.448'], ['D26.310'], ['G07.690.773.984'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['C01.150.252.400.310.330'], ['D23.101.387', 'G05.695.450'], ['Z01.058.290.190.380'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Named Groups [M]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 |
Streptococcal toxic shock syndrome: a description of 14 cases from North Yorkshire, UK. | OBJECTIVE: To analyze the clinical and laboratory features of patients diagnosed with streptococcal toxic shock syndrome (TSS) in North Yorkshire from 1986 to 1999.METHODS: Records of patients with features satisfying the published criteria for streptococcal TSS were reviewed from laboratory and clinical records made a... | ['Adult', 'Aged', 'Aged, 80 and over', 'Anti-Bacterial Agents', 'Anti-Inflammatory Agents, Non-Steroidal', 'Fasciitis, Necrotizing', 'Female', 'Humans', 'Male', 'Middle Aged', 'Risk Factors', 'Shock, Septic', 'Streptococcal Infections', 'Streptococcus pyogenes', 'Treatment Outcome', 'United Kingdom'] | 12,010,172 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['D27.505.954.122.085'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['C05.321.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.600.800.725', 'N05.715.350.200.700', 'N05.715.3... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Diminution of dopaminergic neurons in the substantia nigra of sporadic amyotrophic lateral sclerosis. | The substantia nigra was examined immunohistochemically using the antibody to tyrosine hydroxylase in 15 patients with sporadic amyotrophic lateral sclerosis (ALS). The number of dopaminergic neurons was diminished in the substantia nigra of seven cases. The diminution was not related to the age, duration of the illnes... | ['Aged', 'Aged, 80 and over', 'Amyotrophic Lateral Sclerosis', 'Dementia', 'Dopamine', 'Female', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Neurons', 'Ophthalmoplegia', 'Substantia Nigra', 'Tissue Fixation', 'Tyrosine 3-Monooxygenase'] | 7,901,781 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['C10.228.854.139', 'C10.574.562.250', 'C10.574.950.050', 'C10.668.467.250', 'C18.452.845.800.050'], ['C10.228.140.380', 'F03.615.400'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.426.559.389.657.166.175.342'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E0... | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Strategies to improve the medical device life cycle in Mexico. | OBJECTIVE: To analyze the role of stakeholders to three alternative strategies to improve processes and practices regarding the regulation, assessment, and management of orthopaedic medical devices in Mexico.MATERIALS AND METHODS: The study was based on document analysis and 17 structured interviews with multiple key a... | ['Feasibility Studies', 'Female', 'Government Agencies', 'Humans', 'Male', 'Mexico', 'Orthopedic Equipment', 'Public Policy', 'Stakeholder Participation', 'Surveys and Questionnaires'] | 30,137,948 | [['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['I01.409.418', 'N03.540.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.589'], ['E07.858.442'], ['I01.655.500.608', 'I01.880.604.825.608', 'N03.623.500.608'], ['I01.738.805', 'I03.743'], ['E05.318.308.980', 'N05.71... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Occurrence of nighttime gastroesophageal reflux in disturbed and normal sleepers. | BACKGROUND & AIMS: It is not uncommon in a sleep laboratory to encounter individuals who have complaints of disturbed sleep, but who do not meet the criteria for a sleep disorder when evaluated by polysomnography. Because gastroesophageal reflux is known to occur in many individuals without their awareness, it is possi... | ['Adolescent', 'Adult', 'Esophageal pH Monitoring', 'Female', 'Gastroesophageal Reflux', 'Humans', 'Male', 'Middle Aged', 'Polysomnography', 'Sleep Wake Disorders'] | 18,928,935 | [['M01.060.057'], ['M01.060.116'], ['E01.370.372.255', 'E01.370.520.215'], ['C06.405.117.119.500.484'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.520.625'], ['C10.886', 'C23.888.592.796', 'F03.870']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Glomerular cell proliferation and apoptosis in uninephrectomized spontaneously hypertensive rats. | We studied renal function, glomerular cell proliferation and apoptosis for three months after uninephrectomy (UNX) in young, male, spontaneously hypertensive rats (SHR). Apoptosis was assessed by in situ dUTP biotin nick-end labeling method (TUNEL) and by propidium iodide staining. Proliferation rate was determined by ... | ['Actins', 'Animals', 'Apoptosis', 'Blood Pressure', 'Blotting, Northern', 'Cell Division', 'DNA, Complementary', 'Gene Expression', 'Hypertension, Renal', 'In Situ Nick-End Labeling', 'Kidney Glomerulus', 'Male', 'Nephrectomy', 'Proliferating Cell Nuclear Antigen', 'Proto-Oncogene Proteins c-bcl-2', 'RNA, Messenger', ... | 9,839,281 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['B01.050'], ['G04.146.954.035'], ['E01.370.600.875.249', 'G09.330.380.076'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['D13.444.308.497.220', 'D13.444.600.223.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The role of angiotensin II type 1a receptor on intestinal epithelial cells following small bowel resection in a mouse model. | AIM: We have previously shown that inhibition of angiotensin converting enzyme (ACE) significantly reduced intestinal epithelial cell (EC) apoptosis and improved morphometric intestinal adaptation in a mouse model of massive small-bowel resection (SBR). This study attempted to further examine the downstream signaling f... | ['Adaptation, Physiological', 'Angiotensin II Type 1 Receptor Blockers', 'Animals', 'Apoptosis', 'Cell Proliferation', 'Epithelial Cells', 'Intestinal Mucosa', 'Intestine, Small', 'Losartan', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Models, Animal', 'Receptor, Angiotensin, Type 1', 'Signal Transduction'] | 18,989,682 | [['G07.025', 'G16.012.500'], ['D27.505.519.162.500'], ['B01.050'], ['G04.146.954.035'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.436'], ['A03.556.124.369', 'A10.615.550.444'], ['A03.556.124.684'], ['D02.455.426.559.389.185.475', 'D03.383.129.308.507', 'D03.383.129.617.467'], ['B01.050.150.900.649.313.992.635.505.5... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The development of Drink Less: an alcohol reduction smartphone app for excessive drinkers. | Excessive alcohol consumption poses a serious problem for public health. Digital behavior change interventions have the potential to help users reduce their drinking. In accordance with Open Science principles, this paper describes the development of a smartphone app to help individuals who drink excessively to reduce ... | ['Alcohol Drinking', 'Alcohol-Related Disorders', 'Cognitive Behavioral Therapy', 'Feedback, Psychological', 'Humans', 'Mobile Applications', 'Models, Theoretical', 'Smartphone', 'Telemedicine', 'Therapy, Computer-Assisted'] | 29,733,406 | [['F01.145.317.269'], ['C25.775.100', 'F03.900.100'], ['F04.754.137.350'], ['F01.058.288', 'F04.754.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.900.685'], ['E05.599'], ['L01.178.847.698.300.250', 'L01.224.230.260.550.500.750'], ['H02.403.840', 'L01.178.847.652', 'N04.590.374.800'], ['E02.950', 'L0... | ['Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Cardiac resynchronisation therapy associated with pulmonary artery banding in an adult with severe right ventricular dysfunction after Mustard repair for complete transposition of the great arteries: results after 2 years of follow-up. | Late dysfunction of the systemic right ventricle in patients with complete transposition of the great arteries after Mustard or Senning procedures and progressive deterioration of the clinical status has been demonstrated. However, evidence-based data on the effective therapy for systemic right ventricular dysfunction ... | ['Adult', 'Death, Sudden, Cardiac', 'Defibrillators, Implantable', 'Echocardiography, Doppler', 'Humans', 'Magnetic Resonance Imaging, Cine', 'Male', 'Pulmonary Artery', 'Severity of Illness Index', 'Transposition of Great Vessels', 'Treatment Outcome', 'Tricuspid Valve Insufficiency', 'Ventricular Dysfunction, Right'] | 23,402,375 | [['M01.060.116'], ['C14.280.383.220', 'C23.550.260.322.250'], ['E07.305.250.159.175', 'E07.305.250.319.175', 'E07.695.202.175'], ['E01.370.350.130.750.220', 'E01.370.350.850.220.220', 'E01.370.350.850.850.220', 'E01.370.370.380.220.220'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500.510'], ['A... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Disease-on-a-chip: mimicry of tumor growth in mammary ducts. | We present a disease-on-a-chip model in which cancer grows within phenotypically normal breast luminal epithelium on semicircular acrylic support mimicking portions of mammary ducts. The cells from tumor nodules developing within these hemichannels are morphologically distinct from their counterparts cultured on flat s... | ['Antineoplastic Agents', 'Breast Neoplasms', 'Cell Culture Techniques', 'Cell Survival', 'Cells, Cultured', 'Coculture Techniques', 'Epithelial Cells', 'Female', 'Humans', 'Integrin alpha6', 'Mammary Glands, Human', 'Microfluidic Analytical Techniques', 'Zonula Occludens-1 Protein'] | 24,202,525 | [['D27.505.954.248'], ['C04.588.180', 'C17.800.090.500'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['G04.346'], ['A11.251'], ['E05.481.500.374'], ['A11.436'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.776.543.750.705.408.100.550'], ['A01.236.249', 'A10.336.532'], ['E05.... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Distribution of anionic sites in gut tissue: an electron-microscopical study. | A new one-step incubation method using cationic gold colloid was applied to reveal anionic moieties in rat colonic mucosa. Gold particles were detected in all cellular nuclei, basement membranes, mast cell granules and collagen fibres, while the luminal surfaces of all vascular endothelial cells were devoid of gold lab... | ['Animals', 'Anions', 'Colon', 'Gold', 'Histocytochemistry', 'Intestinal Mucosa', 'Microscopy, Electron', 'Rats', 'Rats, Inbred WKY'] | 1,878,952 | [['B01.050'], ['D01.248.497.158'], ['A03.556.124.526.356', 'A03.556.249.249.356'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['E01.370.225.500.607', 'E01.370.225.750.551', 'E05.200.500.607', 'E05.200.750.551', 'H01.158.100.656.234', 'H01.158.201.344', 'H01.181.122.573'], ['A03.556.124.369', 'A10.615.55... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Genotoxicity of acrylamide and glycidamide. | BACKGROUND: Acrylamide, a known rodent carcinogen, is found in the human diet. However, the mechanism by which acrylamide exerts its carcinogenic effects remains unclear.METHODS: Normal human bronchial epithelial cells and Big Blue mouse embryonic fibroblasts that carry a lambda phage cII transgene were treated in vitr... | ['Acrylamide', 'Adenine', 'Animals', 'Cell Culture Techniques', 'Cytosine', 'DNA Adducts', 'Dose-Response Relationship, Drug', 'Epoxy Compounds', 'Fibroblasts', 'Guanine', 'Humans', 'Mice', 'Mutagens', 'Mutation', 'Polymerase Chain Reaction', 'Respiratory Mucosa', 'Thymine', 'Transferases'] | 15,240,786 | [['D02.065.122.015', 'D02.241.081.069.094.015'], ['D03.633.100.759.138'], ['B01.050'], ['E01.370.225.500.223', 'E05.200.500.265', 'E05.242.223', 'E05.481.500.249'], ['D03.383.742.698.421'], ['D13.444.308.135', 'G05.200.104'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.355.291.411'], ['A11.329.228'], ['D03.633.100.75... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
An optically coupled sensor for the measurement of currents induced by MRI gradient fields into endocardial leads. | OBJECT: The gradient fields generated during magnetic resonance imaging (MRI) procedures have the potential to induce electrical current on implanted endocardial leads. Whether this current can result in undesired cardiac stimulation is unknown.MATERIALS AND METHODS: This paper provides a detailed description of how to... | ['Electrodes, Implanted', 'Electromagnetic Fields', 'Endocardium', 'Equipment Design', 'Equipment Failure Analysis', 'Humans', 'Magnetic Resonance Imaging', 'Optical Devices', 'Pacemaker, Artificial', 'Radiometry', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Transducers'] | 25,304,063 | [['E07.305.250.319', 'E07.695.202'], ['G01.358.500.260', 'G01.358.750.500'], ['A07.541.207'], ['E05.320'], ['E05.325.192'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['E07.632'], ['E07.305.250.750'], ['E05.799'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Polyphasic approach to the characterisation of marine luminous bacteria. | Fifteen luminous bacterial strains were isolated from the Tyrrhenian Sea coastal waters off northeastern Sicily and characterised by a combination of phenotypic and molecular tests in order to identify them and to determine their intraspecific genetic variability. Five luminous type strains, Vibrio splendidus NCIMB 1, ... | ['Base Sequence', 'DNA, Bacterial', 'DNA, Ribosomal', 'Luminescent Measurements', 'Molecular Sequence Data', 'Phenotype', 'Plasmids', 'RNA, Ribosomal, 16S', 'Random Amplified Polymorphic DNA Technique', 'Restriction Mapping', 'Seawater', 'Sequence Analysis, DNA', 'Vibrionaceae'] | 10,229,952 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D13.444.308.212'], ['D13.444.308.475'], ['E05.196.712.516'], ['L01.453.245.667'], ['G05.695'], ['G05.360.600'], ['D13.444.735.686.670'], ['E05.393.620.500.687', 'E05.601.700'], ['E05.393.183.620.650', 'E05.393.712'], ['G16.500.275.725.500'], ['E05.393.760.70... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Phase I trial of combined treatment with ch14.18 and R24 monoclonal antibodies and interleukin-2 for patients with melanoma or sarcoma. | PURPOSE: We conducted a phase I trial of interleukin 2 (IL-2) in combination with chimeric 14.18 (ch14.18) and murine R24 antibodies to determine the maximal tolerated dose (MTD), immunological effects, and toxicity of this treatment combination.EXPERIMENTAL DESIGN: Twenty-seven patients with either melanoma (23 patien... | ['Adult', 'Angioedema', 'Antibodies, Anti-Idiotypic', 'Antibodies, Monoclonal', 'Antibody-Dependent Cell Cytotoxicity', 'Combined Modality Therapy', 'Dose-Response Relationship, Immunologic', 'Drug Administration Schedule', 'Female', 'Humans', 'Immunologic Factors', 'Immunotherapy', 'Interleukin-2', 'Killer Cells, Lymp... | 16,187,086 | [['M01.060.116'], ['C14.907.079', 'C17.800.862.945.066', 'C20.543.480.904.066'], ['D12.776.124.486.485.114.071', 'D12.776.124.790.651.114.071', 'D12.776.377.715.548.114.071'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['G12.287.070'], ['E02.186'], ['G12.300'], ['E02.... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Differential hepatoprotective mechanisms of rutin and quercetin in CCl(4)-intoxicated BALB/cN mice. | AIM: To investigate the mechanisms underlying the protective effects of quercetin-rutinoside (rutin) and its aglycone quercetin against CCl(4)-induced liver damage in mice.METHODS: BALB/cN mice were intraperitoneally administered rutin (10, 50, and 150 mg/kg) or quercetin (50 mg/kg) once daily for 5 consecutive days, f... | ['Animals', 'Biphenyl Compounds', 'Carbon Tetrachloride Poisoning', 'Chemical and Drug Induced Liver Injury', 'Dose-Response Relationship, Drug', 'Free Radical Scavengers', 'Immunohistochemistry', 'Injections, Intraperitoneal', 'Liver', 'Liver Function Tests', 'Male', 'Mice', 'Mice, Inbred BALB C', 'Molecular Structure... | 22,902,988 | [['B01.050'], ['D02.455.426.559.389.185'], ['C25.723.177'], ['C06.552.100', 'C25.100.562', 'C25.723.260'], ['G07.690.773.875', 'G07.690.936.500'], ['D27.505.519.217.500'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Murine oncornavirus high-molecular-weight RNA structure thermal stepwise dissociation of 70S murine leukemia-sarcoma virus to subunits and low-molecular-weight associated RNAs. | The thermal dissociation into subunits and low-molecular-weight (LMW) associated RNAs of the aggregate structure of 70S RNA of a murine leukemia sarcoma viral complex was studied. By polyacrylamide-agarose gel electrophoresis, it was found that at low temperature a fraction of the genome was converted into an intermedi... | ['Electrophoresis, Polyacrylamide Gel', 'Genotype', 'Hot Temperature', 'Molecular Weight', 'Moloney murine leukemia virus', 'RNA, Viral'] | 1,117,485 | [['E05.196.401.402', 'E05.301.300.319'], ['G05.380'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G02.494'], ['B04.613.807.375.525.596', 'B04.820.650.375.525.596'], ['D13.444.735.828']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Short-term effects of minimally invasive dynamic neutralization system for the treatment of lumbar spinal stenosis: An observational study. | The aim of the study was to evaluate the safety and short-term effects of dynamic stabilization via minimally invasive system for degenerative lumbar spinal stenosis. Patients with degenerative lumbar spinal stenosis and treated with Transforaminal Lumbar Interbody Fusion via minimally invasive minimally system (mis-TL... | ['Adult', 'Decompression, Surgical', 'Female', 'Humans', 'Internal Fixators', 'Intervertebral Disc Displacement', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Minimally Invasive Surgical Procedures', 'Range of Motion, Articular', 'Spinal Fusion', 'Spinal Stenosis', 'Treatment Outcome'] | 29,851,799 | [['M01.060.116'], ['E04.188'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.695.370', 'E07.858.442.660.460', 'E07.858.690.725.460'], ['C05.116.900.307', 'C23.300.707.952'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['E04.502'], ['E01.370.600.700', 'G11.427.760'], ['E04.555.100.700'], ['C05.116.900.825'], ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Peripheral and central measurements of bone mineral density are equally strongly associated with clinical risk factors for osteoporosis. | The aim of this study was to determine whether forearm bone mineral density (BMD) measurements are affected by clinical risk factors for osteoporosis to the same extent as spine and hip BMD. The study population consisted of 1,009 female patients and volunteers, of whom 238 were premenopausal. Women were placed into se... | ['Absorptiometry, Photon', 'Adult', 'Aged', 'Bone Density', 'Bone Diseases, Metabolic', 'Female', 'Forearm', 'Humans', 'Middle Aged', 'Osteoporosis, Postmenopausal', 'Prevalence', 'Research Design', 'Risk Factors', 'Spine'] | 17,308,990 | [['E01.370.350.700.024', 'E05.196.712.224.187'], ['M01.060.116'], ['M01.060.116.100'], ['G11.427.100'], ['C05.116.198', 'C18.452.104'], ['A01.378.800.585'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C05.116.198.579.610', 'C18.452.104.579.610'], ['E05.318.308.985.525.750', 'N01.224.935.597.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 |
Masking with faces in central visual field under a variety of temporal schedules. | With a few exceptions, previous studies have explored masking using either a backward mask or a common onset trailing mask, but not both. In a series of experiments, we demonstrate the use of faces in central visual field as a viable method to study the relationship between these two types of mask schedule. We tested o... | ['Adult', 'Analysis of Variance', 'Attention', 'Facial Recognition', 'Humans', 'Pattern Recognition, Visual', 'Perceptual Masking', 'Photic Stimulation', 'Time Factors', 'Visual Fields'] | 26,381,296 | [['M01.060.116'], ['E05.318.740.150', 'N05.715.360.750.125', 'N06.850.520.830.150'], ['F02.830.104.214'], ['F02.463.593.524.250.500', 'F02.463.593.524.500.500', 'F02.463.593.932.622.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ['F02.463.593.071.594', 'F02.463.5... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Hypertrophy of labia minora: experience with 163 reductions. | OBJECTIVE: Our purpose was to describe the surgical procedure, its results, and its complications and to determine whether patients are satisfied with surgical reduction of labia minora in cases of hypertrophy.STUDY DESIGN: The records of 163 patients who underwent reduction of the labia minora during a 9-year period w... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Female', 'Humans', 'Hypertrophy', 'Middle Aged', 'Pain, Postoperative', 'Patient Satisfaction', 'Reoperation', 'Surgical Wound Dehiscence', 'Surveys and Questionnaires', 'Vulva'] | 10,649,154 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.300.775'], ['M01.060.116.630'], ['C23.550.767.700', 'C23.888.592.612.832'], ['F01.100.150.750.625', 'F01.145.488.887.625', 'N04.452.822.700', 'N05.300.150.800.625', 'N05.715.360.600'], ['E04.6... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Colorful calcium sensors. | (R)evolution of protein-based calcium sensors: Expanding the toolbox of genetically encoded calcium sensors with new colors and traits is important for understanding calcium signaling and its relation to other intracellular pathways. Campbell and co-workers have used a new directed-evolution strategy to develop a rich ... | ['Calcium', 'Calcium Signaling', 'Fluorescent Dyes', 'Luminescent Proteins'] | 22,234,942 | [['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G02.111.820.800.100', 'G03.143.500.100', 'G04.835.800.100'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D12.776.532']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Melatonin protection on mercury-exerted brain toxicity in the rat. | The effect of melatonin on the neurotoxicity induced by mercuric chloride was studied. Adult rats were fed orally with two different doses of mercuric chloride (2 mg; 4 mg/kg body weight) to evaluate brain toxicity with respect to cerebral hemisphere, cerebellum, and medulla oblongata regions for 60 days with or withou... | ['Animals', 'Antioxidants', 'Blood Glucose', 'Body Weight', 'Brain', 'Cerebellum', 'Cerebrum', 'Drug Antagonism', 'Environmental Pollutants', 'Enzymes', 'Lipid Peroxidation', 'Male', 'Medulla Oblongata', 'Melatonin', 'Mercuric Chloride', 'Mercury Poisoning', 'Organ Size', 'Rats', 'Rats, Wistar'] | 20,307,147 | [['B01.050'], ['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['D09.947.875.359.448.500'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['A08.186.211'], ['A08.186.211.132.810.428.200'], ['A08.186.211.200.885.287'], ['G07.690.773.968.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The History of Duke Thoracic Surgery. | Since 1931, Duke Thoracic Surgery has been defined by excellence in patient care, research, and the education of leaders in surgery. In this work, the history, contributions, historic figures, and current structure of the program are reviewed. The program has cultivated a commitment to surgical investigation and traini... | ['Academic Medical Centers', 'Biomedical Research', 'Diffusion of Innovation', 'Education, Medical', 'History, 20th Century', 'History, 21st Century', 'Humans', 'Leadership', 'North Carolina', 'Program Development', 'Program Evaluation', 'Thoracic Surgery', 'Thoracic Surgical Procedures'] | 26,811,042 | [['N02.278.020'], ['H01.770.644.145'], ['L01.143.320'], ['I02.358.399'], ['K01.400.504.968'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.609'], ['Z01.107.567.875.075.475', 'Z01.107.567.875.750.530'], ['N04.452.760'], ['E05.337.820', 'N04.761.685', 'N05.715.360.650'], ['H02.403.810.8... | ['Health Care [N]', 'Disciplines and Occupations [H]', 'Information Science [L]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 |
Expression of collagen alpha1(I) mRNA variants during tooth and bone formation in the rat. | Collagen alpha1(I) mRNA is composed of two variants of 5 and 6 kb, differing in the length of the 3' untranslated region. In this work, the nucleotide sequences of the two rat mRNA variants were compared, and their expression pattern in cells forming bone, dentin, and cementum were analyzed. The sequences were determin... | ["3' Untranslated Regions", 'Animals', 'Blotting, Northern', 'Cementogenesis', 'Collagen', 'Dentinogenesis', 'Gene Expression Regulation, Developmental', 'In Situ Hybridization', 'Molecular Sequence Data', 'Odontogenesis', 'Osteogenesis', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Reverse Transcriptase Polymera... | 10,065,941 | [['D13.444.735.544.875.880', 'D13.444.735.790.878.880', 'G05.360.340.024.220.880.880', 'G05.360.340.024.340.137.910.880'], ['B01.050'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['G07.345.500.325.377.124'], ['D05.750.078.280', 'D12.776.860.300.250'], ['G07.345.500.325.377.186'], ['G05.308.310'], ['E01.370.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Genetic control of morphogenesis of Pseudomonas aeruginosa transposable phage D3112]. | The influence of ts mutations in the early and late genes of transposable phage D3112 on phage morphogenesis was studied. The mutations in the early genes A, B and C were shown to suppress morphogenesis of D3112. Six genes (D, E, F, G, H and I), located from 14 to 29 kbp of the phage physical map, control morphogenesis... | ['Bacteriophages', 'Genes, Viral', 'Microscopy, Electron', 'Morphogenesis', 'Mutation', 'Pseudomonas aeruginosa'] | 2,517,491 | [['B04.123'], ['G05.360.340.024.340.364.875', 'G05.360.340.358.024.875', 'G05.360.340.358.840.500'], ['E01.370.350.515.402', 'E05.595.402'], ['G07.345.500'], ['G05.365.590'], ['B03.440.400.425.625.625.100', 'B03.660.250.580.590.050']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Biodiesel production from hydrolysate of Cyperus esculentus waste by Chlorella vulgaris. | To reduce the cost of algal-based biodiesel, a waste material from oil industry, Cyperus esculentus waste, was used as the carbon source of the oleaginous microalgae Chlorella vulgaris. It demonstrated that C. vulgaris grew better in C. esculentus waste hydrolysate (CEWH(1)) than in glucose medium under the same reduci... | ['Batch Cell Culture Techniques', 'Biofuels', 'Carbohydrates', 'Chlorella vulgaris', 'Cyperus', 'Fatty Acids', 'Glucose', 'Hydrolysis', 'Lipids', 'Microalgae', 'Oxidation-Reduction', 'Time Factors', 'Waste Products'] | 23,548,401 | [['E05.481.500.249.124'], ['D20.147', 'N06.230.132.644.124'], ['D09'], ['B01.650.940.150.469.400'], ['B01.650.940.800.575.912.250.312.199'], ['D10.251'], ['D09.947.875.359.448'], ['G02.380'], ['D10'], ['B05.080.500.600.500'], ['G02.700', 'G03.295.531'], ['G01.910.857'], ['D20.944', 'N06.850.460.710']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Stochastic variation in telomere shortening rate causes heterogeneity of human fibroblast replicative life span. | The replicative life span of human fibroblasts is heterogeneous, with a fraction of cells senescing at every population doubling. To find out whether this heterogeneity is due to premature senescence, i.e. driven by a nontelomeric mechanism, fibroblasts with a senescent phenotype were isolated from growing cultures and... | ['Blotting, Southern', 'Bromodeoxyuridine', 'Cell Division', 'Cell Line', 'Cell Separation', 'Cellular Senescence', 'DNA Damage', 'Enzyme-Linked Immunosorbent Assay', 'Fibroblasts', 'Flow Cytometry', 'Genes, Reporter', 'Humans', 'Oxidative Stress', 'Oxygen', 'Phenotype', 'Stochastic Processes', 'Telomerase', 'Telomere'... | 14,963,037 | [['E05.196.401.114', 'E05.301.300.087', 'E05.601.150'], ['D03.383.742.680.852.300.150', 'D13.570.230.430.196', 'D13.570.685.852.300.150'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['G04.043'], ['G05.200'], ['E05... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Large-scale fabrication of two-dimensional spider-web-like gelatin nano-nets via electro-netting. | For the first time, two-dimensional (2D) gelatin nano-nets are fabricated by regulating the solution properties and several process parameters during electrospinning/electro-netting. The spider-web-like nano-nets that comprise interlinked one-dimensional (1D) ultrathin nanowires (10-35 nm) are stacked layer-by-layer an... | ['Biocompatible Materials', 'Gelatin', 'Humidity', 'Hydrogen Bonding', 'Materials Testing', 'Membranes, Artificial', 'Nanowires', 'Polymers', 'Porosity', 'Solutions', 'Solvents', 'Surface Properties', 'Temperature'] | 21,550,787 | [['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D12.776.860.476'], ['G16.500.275.063.725.310', 'G16.500.750.775.310', 'N06.230.150.372', 'N06.230.300.100.725.310'], ['G02.282'], ['E05.570'], ['D25.479', 'J01.637.051.479', 'J01.637.087.500'], ['J01.637.512.925'], ['D05.750', 'D25.720', 'J01.637.051.720'], ['G01.37... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Granulosa cell tumor--clinical group and literature review]. | OBJECTIVE: To present a review of literature and to analyse a clinical retrospective series of patients with granulosa cell tumor.DESIGN: Retrospective study and review.SETTING: Department of Obstetrics and Gynaecology, First Faculty of Medicine, Prague, Czech Republic.METHODS: Retrospective analysis of age, stage, sur... | ['Female', 'Granulosa Cell Tumor', 'Humans', 'Ovarian Neoplasms', 'Retrospective Studies', 'Survival Rate'] | 10,953,492 | [['C04.557.475.750.656', 'C04.588.322.455.398', 'C13.351.500.056.630.705.398', 'C13.351.937.418.685.398', 'C19.344.410.398', 'C19.391.630.705.398'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.322.455', 'C13.351.500.056.630.705', 'C13.351.937.418.685', 'C19.344.410', 'C19.391.630.705'], ['E05.318.372.500... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Subregional loss of putaminal efferents to the basal ganglia output nuclei may cause parkinsonism in striatonigral degeneration. | In this study, we examined the topographic involvement of the putaminal projection neurons and their axons in the globus pallidus and substantia nigra, which we visualized by calcineurin immunostaining, in the basal ganglia of patients with striatonigral degeneration (SND). In all cases examined, there was a marked dec... | ['Aged', 'Basal Ganglia', 'Corpus Striatum', 'Efferent Pathways', 'Female', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged', 'Models, Neurological', 'Nerve Degeneration', 'Parkinson Disease', 'Putamen'] | 8,857,740 | [['M01.060.116.100'], ['A08.186.211.200.885.287.249'], ['A08.186.211.200.885.287.249.487'], ['A08.612.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.51... | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Dual neutralisation of interleukin-17A and interleukin-17F with bimekizumab in patients with active ankylosing spondylitis: results from a 48-week phase IIb, randomised, double-blind, placebo-controlled, dose-ranging study. | OBJECTIVES: Bimekizumab selectively neutralises both interleukin (IL)-17A and IL-17F. We report efficacy and safety in a phase IIb dose-ranging study in patients with active ankylosing spondylitis (AS).METHODS: Adults with AS (fulfilling modified New York criteria) were randomised 1:1:1:1:1 to bimekizumab 16 mg, 64 mg,... | ['Adult', 'Antibodies, Monoclonal, Humanized', 'Biomarkers', 'Dose-Response Relationship, Drug', 'Double-Blind Method', 'Drug Administration Schedule', 'Europe', 'Female', 'Follow-Up Studies', 'Humans', 'Interleukin-17', 'Internationality', 'Male', 'Maximum Tolerated Dose', 'Middle Aged', 'Reference Values', 'Risk Asse... | 32,253,184 | [['M01.060.116'], ['D12.776.124.486.485.114.224.060', 'D12.776.124.790.651.114.224.060', 'D12.776.377.715.548.114.224.200'], ['D23.101'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E02.319.283'], ['Z01.542'], ['E05.318.372.500.750.249'... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Prostaglandin F2 alpha isopropyl ester versus iloprost phenacyl ester in rabbit and beagle eyes. | One and 2 micrograms of prostaglandin F2 alpha isopropyl ester (PGF2 alpha -IE) applied topically to the rabbit eye caused a biphasic response. The hypotensive phase was dose-dependent with a maximum reduction in intraocular pressure (IOP) of 9.4 +/- 1.7 mmHg at a dose of 2 micrograms. In beagles, 0.4 to 2 micrograms t... | ['Administration, Topical', 'Animals', 'Aqueous Humor', 'Cyclic AMP', 'Dinoprost', 'Dogs', 'Dose-Response Relationship, Drug', 'Epoprostenol', 'Hyperemia', 'Hypromellose Derivatives', 'Iloprost', 'Intraocular Pressure', 'Methylcellulose', 'Pupil', 'Rabbits', 'Time Factors', 'Tonometry, Ocular'] | 2,540,937 | [['E02.319.267.120'], ['B01.050'], ['A09.371.060.067.070', 'A12.207.270.040'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D10.251.355.255.550.400.200', 'D23.469.050.175.725.400.200'], ['B01.050.150.900.649.313.750.250.216.200'], ['G07.690.773.875', 'G07.690.936.5... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Glycine-assisted hydrothermal synthesis of peculiar porous alpha-Fe2O3 nanospheres with excellent gas-sensing properties. | In this work, peculiar porous alpha-Fe(2)O(3) nanospheres were fabricated by a glycine-assisted hydrothermal method. They have large mesopores (ca. 10nm) in the core and small mesopores (<4 nm) in the shell. To our best knowledge, there have been so far no reports on the synthesis of such peculiar porous alpha-Fe(2)O(3... | ['Electrochemical Techniques', 'Electrodes', 'Ethanol', 'Ferric Compounds', 'Gases', 'Glycine', 'Metal Nanoparticles', 'Porosity', 'Temperature'] | 20,103,134 | [['E05.301'], ['E07.305.250'], ['D02.033.375'], ['D01.490.100'], ['D01.362'], ['D12.125.481'], ['J01.637.512.600.500'], ['G01.374.710'], ['G01.906.595', 'G16.500.275.063.725.710', 'G16.500.750.775.710', 'N06.230.150.450', 'N06.230.300.100.725.710']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
The Accordant Trend of Both Parameters (rgs Expression and cAMP Content) Follows the Pattern of Development of Fruiting Body in Volvariella volvacea. | The formation of fruiting body in Volvariella volvacea is affected by endogenous genes and environmental factors. However, its regulation at a molecular level is still poorly understood. To study the genes involved in the formation of fruiting body, we cloned a new regulator of the G protein signaling (RGS) encoding ge... | ['Cloning, Molecular', 'Cyclic AMP', 'Fruiting Bodies, Fungal', 'Fungal Proteins', 'Gene Expression Profiling', 'Gene Expression Regulation, Fungal', 'Gene Order', 'Phylogeny', 'Transcriptome', 'Volvariella'] | 26,264,785 | [['E05.393.220'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['A19.374'], ['D12.776.354'], ['E05.393.332'], ['G05.308.330'], ['G05.340'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['G02.111.873.750', 'G05.297.700.750', 'G05.360.920'], ['B01.300.179.100.875']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Practical guide to understanding the need for clinical practice guidelines. | With recent changes in the landscape of health care, clinical practice guidelines (CPGs) have proliferated. Attitudes about guidelines differ considerably, forming 2 competing viewpoints with considerable tension between them. Some feel CPGs are unneeded or are efforts to create automated "cookie cutter" medical practi... | ['Attitude of Health Personnel', 'Delivery of Health Care', 'Education, Medical', 'Evidence-Based Medicine', 'Humans', 'Insurance, Health', 'Practice Guidelines as Topic', 'United States'] | 23,625,796 | [['F01.100.050', 'N05.300.100'], ['N04.590.374', 'N05.300'], ['I02.358.399'], ['H02.249.750', 'H02.403.200.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N03.219.521.576.343'], ['N04.761.700.350.650', 'N05.700.350.650'], ['Z01.107.567.875']] | ['Psychiatry and Psychology [F]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 1 |
Regional differences in hypoxic depolarization and swelling in hippocampal slices. | Pyramidal neurons in the CA1 region of the hippocampus are highly vulnerable to damage from hypoxia-ischemia, whereas neurons in the CA3 region and the dentate gyrus are more resistant. A similar pattern of vulnerability to loss of synaptic and membrane function occurs in the in vitro hippocampal slice preparation, sug... | ['Animals', 'Brain Edema', 'Cortical Spreading Depression', 'Dentate Gyrus', 'Electric Stimulation', 'Electrophysiology', 'Hypoxia, Brain', 'Image Processing, Computer-Assisted', 'In Vitro Techniques', 'Light', 'Male', 'Membrane Potentials', 'Pyramidal Cells', 'Rats', 'Rats, Sprague-Dawley'] | 10,669,514 | [['B01.050'], ['C10.228.140.187'], ['G11.561.200.500.300'], ['A08.186.211.180.405.200', 'A08.186.211.200.885.287.500.345.200'], ['E05.723.402'], ['H01.158.344.528', 'H01.158.782.236'], ['C10.228.140.624', 'C23.888.852.079.797'], ['L01.224.308'], ['E05.481'], ['G01.358.500.505.650', 'G01.590.540', 'G01.750.250.650', 'G0... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Public health physicians: an endangered species. | BACKGROUND: Questions have arisen regarding the competency levels of the various professions within the public health sector, including those of physicians. Protection of the nation's health requires that physicians on the public health team be competent practitioners of both medicine and public health. Physicians prac... | ['Clinical Competence', 'Competency-Based Education', 'Employment', 'Humans', 'Public Health'] | 11,567,846 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.158.210'], ['N01.824.245'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['H02.403.720', 'N01.400.550', 'N06.850']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 |
[Surface morphology of normal and virus-transformed cells in suspended state and their concanavalin A agglutinability]. | Suspended cells are heterogeneous in respect to their surface microrelief. The distribution of different microrelieves varies in different cultures. It depends on the mode of cell detachment from the substrate - by EDTA or trypsin. Oncogenic transformation is accompanied by both the increase and decrease of microvillou... | ['Agglutination', 'Animals', 'Cell Transformation, Viral', 'Cells, Cultured', 'Concanavalin A', 'Cricetinae', 'Kirsten murine sarcoma virus', 'Mice', 'Microscopy, Electron, Scanning', 'Microvilli', 'Mink', 'Sarcoma, Experimental', 'Simian virus 40', 'Surface Properties', 'Tumor Virus Infections'] | 6,291,200 | [['G02.111.026', 'G12.122.100'], ['B01.050'], ['C04.697.098.500.160', 'C23.550.727.098.500.160', 'G06.920.143'], ['A11.251'], ['D12.776.503.499.500', 'D12.776.765.678.500'], ['B01.050.150.900.649.313.992.635.075.250'], ['B04.265.600.500', 'B04.613.807.375.860.500', 'B04.820.650.375.860.500'], ['B01.050.150.900.649.313.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
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