Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Inhibitory effect of TiO2 | While nanoparticles (NPs) are known to exhibit antimicrobial properties, their effects on symbiotic arbuscular mycorrhizal fungi (AMF) in plant roots has to be carefully examined as NPs particularly of titanium dioxide (TiO2) reach plant roots through varied sources such as fertilisers, plant protection products and ot... | ['Antifungal Agents', 'Apoptosis', 'Cell Survival', 'Metal Nanoparticles', 'Mycorrhizae', 'Oryza', 'Particle Size', 'Plant Roots', 'Titanium', 'Treatment Outcome'] | 28,476,964 | [['D27.505.954.122.136'], ['G04.146.954.035'], ['G04.346'], ['J01.637.512.600.500'], ['A18.400.525', 'A19.690', 'B01.300.655', 'B05.550'], ['B01.650.940.800.575.912.250.822.616'], ['G02.712'], ['A18.400'], ['D01.268.557.800', 'D01.268.956.878', 'D01.552.547.800'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
[Gastric emptying of sucrose and maltose and levels of respective disaccharidases in the small intestinal mucosa of adult rats]. | The gastric emptying of sucrose and maltose solutions at different concentrations, with addition of phenol red (6 mg%) used as a marker, was studied in 144 Wistar male rats. The gastric retention was determined 15 minutes after the orogastric infusion of sucrose and maltose solutions at 2.5%, 5% and 10% and volume of 1... | ['Animals', 'Disaccharidases', 'Gastric Emptying', 'Intestinal Mucosa', 'Intestine, Small', 'Male', 'Maltose', 'Rats', 'Rats, Wistar', 'Sucrose'] | 7,872,866 | [['B01.050'], ['D08.811.277.450.329'], ['G10.261.360.400'], ['A03.556.124.369', 'A10.615.550.444'], ['A03.556.124.684'], ['D09.698.365.450', 'D09.698.629.305.523', 'D09.947.750.523'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['D09.698.629.305.770', 'D09.947.750.770']... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anterior Segment Seeding in Eyes With Retinoblastoma Failing to Respond to Intraophthalmic Artery Chemotherapy. | IMPORTANCE: Anterior chamber seeding following intraophthalmic artery chemotherapy is rarely reported.OBJECTIVES: To describe clinicopathologic observations in eyes in which intraophthalmic artery chemotherapy for retinoblastoma failed and to report anterior chamber involvement.OBSERVATIONS: A retrospective case series... | ['Adolescent', 'Anterior Eye Segment', 'Antineoplastic Combined Chemotherapy Protocols', 'Carboplatin', 'Child', 'Child, Preschool', 'Etoposide', 'Eye Enucleation', 'Eye Neoplasms', 'Female', 'Humans', 'Infant', 'Infusions, Intra-Arterial', 'Male', 'Neoplasm Seeding', 'Ophthalmic Artery', 'Retinal Neoplasms', 'Retinobl... | 26,334,520 | [['M01.060.057'], ['A09.371.060'], ['E02.183.750.500', 'E02.319.077.500', 'E02.319.310.037'], ['D02.257.125'], ['M01.060.406'], ['M01.060.406.448'], ['D02.455.426.559.847.638.960.675.250', 'D04.615.638.960.675.250', 'D09.408.348.275'], ['E04.540.429'], ['C04.588.364', 'C11.319'], ['B01.050.150.900.649.313.988.400.112.4... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Environmental factors shape sediment anammox bacterial communities in hypernutrified Jiaozhou Bay, China. | Bacterial anaerobic ammonium oxidation (anammox) is an important process in the marine nitrogen cycle. Because ongoing eutrophication of coastal bays contributes significantly to the formation of low-oxygen zones, monitoring of the anammox bacterial community offers a unique opportunity for assessment of anthropogenic ... | ['Bacteria, Anaerobic', 'China', 'DNA, Bacterial', 'Environment', 'Eutrophication', 'Genes, Bacterial', 'Geologic Sediments', 'Molecular Sequence Data', 'Oceans and Seas', 'Oxidation-Reduction', 'Phylogeny', 'Quaternary Ammonium Compounds', 'RNA, Ribosomal, 16S', 'Water Microbiology'] | 20,833,786 | [['B03.130'], ['Z01.252.474.164'], ['D13.444.308.212'], ['G16.500.275', 'N06.230'], ['G16.500.285'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['G01.311.330', 'G16.500.320'], ['L01.453.245.667'], ['G01.311.625', 'G16.500.275.725.500.650', 'Z01.756'], ['G02.700', 'G03.295.531... | ['Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 |
Management of patients with stercoral perforation of the sigmoid colon: report of five cases. | To our knowledge, stercoral perforation of the colon is rarely seen with fewer than 90 cases reported in the literature till date. We explored the principles of management to prevent impending mortality in five patients with this condition. Five patients, two males and three females, whose median age was 64 years, had ... | ['Aged', 'Aged, 80 and over', 'Child, Preschool', 'Colon, Sigmoid', 'Constipation', 'Female', 'Humans', 'Intestinal Perforation', 'Male', 'Middle Aged', 'Retrospective Studies'] | 16,489,660 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['M01.060.406.448'], ['A03.556.124.526.356.668', 'A03.556.249.249.356.668'], ['C23.888.821.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C06.405.469.557'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500'... | ['Named Groups [M]', 'Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Safety and efficacy evaluation of lanthanum carbonate for hyperphosphatemia in end-stage renal disease patients. | In end-stage renal disease patients, various abnormalities of bone mineral metabolism adversely affect mortality. Hyperphosphatemia is known to adversely affect mortality and quality of life in chronic kidney disease patients and has been shown to be involved not only in the onset and progression of secondary hyperpara... | ['Bone and Bones', 'Fibroblast Growth Factors', 'Humans', 'Hyperphosphatemia', 'Kidney Failure, Chronic', 'Lanthanum', 'Phosphates', 'Renal Dialysis', 'Time Factors'] | 26,023,014 | [['A02.835.232', 'A10.165.265'], ['D12.644.276.624', 'D12.776.467.624', 'D23.529.624'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.750.199'], ['C12.777.419.780.750.500', 'C13.351.968.419.780.750.500'], ['D01.268.558.362.500', 'D01.552.550.399.500'], ['D01.029.260.700.675.374', 'D01.248.497.158.730', 'D0... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
IL-33 Reverses an Obesity-Induced Deficit in Visceral Adipose Tissue ST2+ T Regulatory Cells and Ameliorates Adipose Tissue Inflammation and Insulin Resistance. | Obesity is associated with insulin resistance and inflammation thought to be caused by a visceral adipose tissue (VAT)-localized reduction in immunoregulatory cells and increase in proinflammatory immune cells. We previously found that VAT regulatory T cells (Tregs) normally express high levels of IL-10 and that expres... | ['Animals', 'Diet, High-Fat', 'Flow Cytometry', 'Inflammation', 'Insulin Resistance', 'Interleukin-1 Receptor-Like 1 Protein', 'Interleukin-33', 'Interleukins', 'Intra-Abdominal Fat', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Obesity', 'Receptors, Interleukin', 'Reverse Transcriptase Polymerase Chain Reaction', 'T-Lymphoc... | 25,870,243 | [['B01.050'], ['G07.203.650.240.267'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['C23.550.470'], ['C18.452.394.968.500', 'G07.690.773.984.617'], ['D12.776.543.750.705.852.420.300.375'], ['D1... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative Analysis of Bilateral Temporomandibular Joints in Patients With Unilateral Temporomandibular Joint Complaints Using Cone Beam Computed Tomography. | OBJECTIVE: This study was to determine if there was any temporomandibular joint (TMJ) indicator that was not statistically different in the controls but was with statistical difference between the bilateral sides in patients with unilateral TMJ complaints using cone beam computed tomography (CBCT).METHODS: TMJ CBCT ima... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Arthrometry, Articular', 'Cone-Beam Computed Tomography', 'Female', 'Humans', 'Image Processing, Computer-Assisted', 'Male', 'Mandibular Condyle', 'Middle Aged', 'Temporomandibular Joint', 'Temporomandibular Joint Disorders', 'Young Adult'] | 26,595,003 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.600.700.500', 'G11.427.760.500'], ['E01.370.350.700.810.810.490', 'E01.370.350.825.810.810.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.308'], ['A02.835.232.781.324.502.632.600', 'A14.521.632.600'], ['M01.060... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
The potential of matrix metalloproteinase-2 as a marker of peritoneal injury, increased solute transport, or progression to encapsulating peritoneal sclerosis during peritoneal dialysis--a multicentre study in Japan. | BACKGROUND: Long-term peritoneal dialysis (PD) leads to peritoneal injury. At worst, peritoneal injury leads to encapsulating peritoneal sclerosis (EPS), which is a serious complication of PD. The mortality rate of EPS is extremely high. To perform PD safely, monitoring of peritoneal injury that leads to EPS is a neces... | ['Aged', 'Ascitic Fluid', 'Biological Transport, Active', 'Dialysis Solutions', 'Disease Progression', 'Female', 'Follow-Up Studies', 'Humans', 'Incidence', 'Japan', 'Kidney Failure, Chronic', 'Male', 'Matrix Metalloproteinase 2', 'Middle Aged', 'Peritoneal Dialysis', 'Peritoneal Diseases', 'Peritoneum', 'Prognosis', '... | 17,035,369 | [['M01.060.116.100'], ['A12.207.119'], ['G03.143.310'], ['D26.776.708.322', 'D27.505.954.578.483', 'D27.720.752.483'], ['C23.550.291.656'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Pyridinium derivatives of histamine are potent activators of cytosolic carbonic anhydrase isoforms I, II and VII. | A series of positively-charged derivatives has been prepared by reaction of histamine with substituted pyrylium salts. These pyridinium histamine derivatives were investigated as activators of the zinc enzyme carbonic anhydrase (CA, EC 4.2.1.1) and more precisely the human isoforms hCA I, II and VII. Activities from th... | ['Animals', 'Carbonic Anhydrase I', 'Carbonic Anhydrase II', 'Carbonic Anhydrase IV', 'Cattle', 'Cytosol', 'Enzyme Activation', 'Histamine', 'Humans', 'Isoenzymes', 'Molecular Structure', 'Phenazopyridine', 'Structure-Activity Relationship'] | 21,369,613 | [['B01.050'], ['D08.811.520.241.300.150.100'], ['D08.811.520.241.300.150.200'], ['D08.811.520.241.300.150.400', 'D12.776.395.550.448.160', 'D12.776.543.484.500.160', 'D12.776.543.550.418.160'], ['B01.050.150.900.649.313.500.380.271'], ['A11.284.430.214.200', 'A11.284.430.429.200', 'A11.284.835.450.200'], ['G02.111.263'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The pathologist's guide to fixatives. | Proper tissue fixation is essential to ensure the highest level of specimen evaluation. Pathologists and laboratory staff are frequently consulted by clinical counterparts regarding what fixative should be used for different tissues or to enable a diagnosis of a specific condition. It is vital for the patient that the ... | ['Fixatives', 'Humans', 'Organ Specificity', 'Pathology', 'Tissue Fixation'] | 25,015,140 | [['D27.720.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G07.650'], ['H02.403.650'], ['E01.370.225.500.620.760.720', 'E01.370.225.750.600.760.720', 'E05.200.500.620.760.720', 'E05.200.750.600.760.720']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of resistance to eprinomectin in gastrointestinal nematodes in a goat herd with pre-existing resistance to benzimidazoles. | We described a first case of resistance to eprinomectin in goat herd in Poland in which resistance to benzimidazoles had been previously reported. The herd was established in 2011 by purchasing several goats from a single herd in south-eastern Poland. Resistance to benzimidazoles in the herd was first reported in 2017.... | ['Animals', 'Anthelmintics', 'Benzimidazoles', 'Drug Resistance', 'Feces', 'Goat Diseases', 'Goats', 'Intestinal Diseases, Parasitic', 'Ivermectin', 'Nematoda', 'Nematode Infections', 'Parasite Egg Count'] | 31,867,918 | [['B01.050'], ['D27.505.954.122.250.075'], ['D03.633.100.103'], ['G07.690.773.984'], ['A12.459'], ['C22.405'], ['B01.050.150.900.649.313.500.380.513'], ['C01.610.432', 'C06.405.469.452'], ['D02.540.576.500.997'], ['B01.050.500.500.294'], ['C01.610.335.508'], ['E01.370.225.932.600', 'E05.200.932.600']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Decreased aEEG continuity and baseline variability in the first 48 hours of life associated with poor short-term outcome in neonates born before 29 weeks gestation. | Amplitude-integrated electroencephalography (aEEG) provides us with a method of assessing brain activity in critically ill neonates. In extremely premature neonates, the aEEG trace is predominantly discontinuous, making it difficult to distinguish between a "normal" and "abnormal" trace. We measured aEEG activity in th... | ['Electroencephalography', 'Female', 'Gestational Age', 'Humans', 'Infant, Extremely Low Birth Weight', 'Infant, Newborn', 'Infant, Premature', 'Infant, Very Low Birth Weight', 'Intracranial Hemorrhages', 'Male', 'Monitoring, Physiologic', 'New South Wales', 'Predictive Value of Tests', 'Prognosis', 'Prospective Studie... | 20,098,343 | [['E01.370.376.300', 'E01.370.405.245'], ['G07.345.500.325.235.968', 'G08.686.320'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520.460.600.500'], ['M01.060.703.520'], ['M01.060.703.520.520'], ['M01.060.703.520.460.600'], ['C10.228.140.300.535', 'C14.907.253.573', 'C23.550.414.913'], ['E01.370.520']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]', 'Diseases [C]', 'Geographicals [Z]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Neuropathy and anti-myelin-associated glycoprotein IgM M proteins: T cell regulation of M protein secretion in vitro. | In patients with plasma cell dyscrasia, individual clones of antibody-producing cells proliferate abnormally and secrete monoclonal antibodies or M proteins in excess. The cause of the monoclonal proliferation of lymphocytes and M protein secretion is unknown and it is not known whether the M protein-secreting B cells ... | ['Autoantibodies', 'B-Lymphocytes', 'Blood Proteins', 'Cell Separation', 'Humans', 'Immunoglobulin M', 'Immunoglobulins', 'In Vitro Techniques', 'Lymphocyte Cooperation', 'Myelin Proteins', 'Myelin-Associated Glycoprotein', 'Peripheral Nervous System Diseases', 'T-Lymphocytes', 'Waldenstrom Macroglobulinemia'] | 2,412,486 | [['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D12.776.124'], ['E01.370.225.500.363', 'E05.200.500.363', 'E05.242.363'], ['B01.050.150.900.649.313.9... | ['Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Inspiratory muscle training in Morquio's syndrome: a case study. | We reported a case of MPS IV A presented with dyspnea on exertion and respiratory muscle weakness. The patient underwent inspiratory muscle training (IMT) using threshold loading for 18 weeks. After 6 weeks of initial IMT, aerobic exercise training consisting of walking was added to the treatment program. Inspiratory m... | ['Adolescent', 'Dyspnea', 'Exercise Therapy', 'Female', 'Follow-Up Studies', 'Humans', 'Mucopolysaccharidosis IV', 'Quality of Life', 'Respiratory Muscles', 'Respiratory Therapy'] | 16,998,925 | [['M01.060.057'], ['C08.618.326', 'C23.888.852.371'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C16.320.565.202.715.655', 'C16.320.565.595.600.655', 'C17.300... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Low sensitivity of F-wave in the electrodiagnosis of carpal tunnel syndrome. | OBJECTIVE: Previous studies showed "F-wave inversion" (F-INV) as a sensitive method in the electrodiagnosis of early stage of carpal tunnel syndrome (CTS). This study aimed at evaluating the sensitivity and specificity of F-wave and nerve conduction velocity (NCV) testing in CTS.METHODS: We consecutively enrolled 244 c... | ['Adult', 'Aged', 'Carpal Tunnel Syndrome', 'Electrodiagnosis', 'Female', 'Humans', 'Male', 'Median Nerve', 'Middle Aged', 'Muscle, Skeletal', 'Neural Conduction', 'Prospective Studies'] | 25,561,074 | [['M01.060.116'], ['M01.060.116.100'], ['C10.668.829.500.500.200', 'C10.668.829.550.200', 'C26.844.150.206'], ['E01.370.405'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A08.800.800.720.050.500'], ['M01.060.116.630'], ['A02.633.567', 'A10.690.552.500'], ['G07.265.753', 'G11.561.601'], ['E05.318.372.500.750.625'... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Co-localization of tissue factor protein and its mRNA in human blood monocytes. | Triggering of both the extrinsic and intrinsic coagulation pathways is mediated by the cell surface receptor Tissue Factor (TF). The ability to observe the cell surface TF protein and its mRNA at the single cell level would facilitate our understanding of the cellular biology of TF in health and diseased states. Employ... | ['Base Sequence', 'Cells, Cultured', 'Humans', 'Immunohistochemistry', 'In Situ Hybridization', 'Molecular Sequence Data', 'Monocytes', 'RNA, Messenger', 'Thromboplastin'] | 8,907,313 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370.225.750.551.512', 'E05.200.500.607.512', 'E05.200.750.551.512', 'E05.478.583', 'H01.158.100.656.234.512', 'H01.158.201.344.512', 'H01.158.201.486.512', 'H01.181.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Biliopancreatic diversion induces villi elongation and cholecystokinin and ghrelin increase. | INTRODUCTION: Factors leading to weight loss and weight stabilization after bariatric surgery are not fully understood. Our aim was to evaluate, in Sprague-Dawley rats, the histological and gut hormonal changes after Larrad-biliopancreatic diversion (Larrad-BPD).MATERIALS AND METHODS: Rats randomly underwent the follow... | ['Animals', 'Biliopancreatic Diversion', 'Body Weight', 'Cholecystokinin', 'Energy Intake', 'Gastric Mucosa', 'Ghrelin', 'Intestinal Mucosa', 'Male', 'Rats', 'Rats, Sprague-Dawley'] | 22,813,405 | [['B01.050'], ['E04.210.120.086', 'E04.210.169'], ['C23.888.144', 'E01.370.600.115.100.160.120', 'E05.041.124.160.750', 'G07.100.100.160.120', 'G07.345.249.314.120'], ['D06.472.317.152', 'D12.644.120'], ['G07.203.650.240.340'], ['A03.556.875.875.440', 'A10.615.550.291'], ['D06.472.699.301', 'D12.644.548.322'], ['A03.55... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The perforation problem in hydatid disease. | Hydatidosis (echinococcosis) is endemic in the Mediterranean region, including Turkey. We evaluated the problem of perforation in hydatidosis. The clinical data on 21 patients with intra-abdominal hydatid cyst perforation who were treated in the last 10 years were evaluated retrospectively. Twelve patients (57%) were m... | ['Adult', 'Aged', 'Echinococcosis', 'Echinococcosis, Hepatic', 'Female', 'Humans', 'Male', 'Middle Aged', 'Recurrence', 'Retinal Perforations', 'Retrospective Studies', 'Turkey'] | 12,201,593 | [['M01.060.116'], ['M01.060.116.100'], ['C01.610.335.190.396'], ['C01.610.335.190.396.314', 'C01.610.518.314', 'C06.552.664.272'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.550.291.937'], ['C11.768.740'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.5... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Clonazepam-related sexual dysfunction in male veterans with PTSD. | Medication-induced sexual dysfunction can significantly interfere with patients' quality of life and lead to poor compliance. This retrospective study examined the records of 100 male veterans with post-traumatic stress disorder (PTSD) selected in alphabetical order from an active treatment file of 230 patients. Forty-... | ['Adult', 'Alprazolam', 'Clonazepam', 'Combat Disorders', 'Diazepam', 'Dose-Response Relationship, Drug', 'Erectile Dysfunction', 'GABA Modulators', 'Humans', 'Lorazepam', 'Male', 'Middle Aged', 'Retrospective Studies', 'Veterans'] | 9,160,580 | [['M01.060.116'], ['D03.633.100.079.080.030'], ['D03.633.100.079.080.070.150'], ['F03.950.750.249'], ['D03.633.100.079.080.070.216'], ['G07.690.773.875', 'G07.690.936.500'], ['C12.294.644.486', 'F03.835.400'], ['D27.505.519.625.240.500', 'D27.505.696.577.240.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D03... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Distinct Clinical Phenotype of Corneal Dystrophy Predicts the p.(Leu450Trp) Substitution in COL8A2. | PURPOSE: The p.(Leu450Trp) substitution in Collagen, Type VIII, Alpha 2 (COL8A2) is associated with an early-onset corneal dystrophy. Here we identify distinct anterior corneal and keratorefractive changes associated with this disease and replicate its distinguishing endothelial characteristics in a new family.METHODS:... | ['Adult', 'Child', 'Collagen Type VIII', 'Corneal Dystrophies, Hereditary', 'Corneal Edema', 'Descemet Stripping Endothelial Keratoplasty', 'Female', 'Humans', 'Male', 'Microscopy, Confocal', 'Pedigree', 'Phenotype', 'Polymerase Chain Reaction', 'Sequence Analysis, DNA', 'Silent Mutation'] | 26,989,952 | [['M01.060.116'], ['M01.060.406'], ['D12.776.860.300.250.400.400'], ['C11.204.236', 'C11.270.162', 'C16.320.290.162'], ['C11.204.267'], ['E02.095.147.725.262', 'E04.540.825.374.112', 'E04.936.580.262'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.515.395', 'E05.595.395'], ['E05.393.673'], ['G05.695']... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Effect of socioeconomic factors on twin pregnancy]. | A material of 336 mothers of twins was divided into four groups on the basis of socioeconomic background. On average, mothers belonging to the first social class delivered at 38.2 +/- 1.6 week of pregnancy and their newborn weighed more than those in other social classes. Careful follow-up at outpatient maternity clini... | ['Adolescent', 'Adult', 'Birth Weight', 'Female', 'Humans', 'Pregnancy', 'Pregnancy Complications', 'Pregnancy, Multiple', 'Prognosis', 'Social Class', 'Socioeconomic Factors', 'Twins'] | 3,765,754 | [['M01.060.057'], ['M01.060.116'], ['C23.888.144.186', 'E01.370.600.115.100.160.120.186', 'E05.041.124.160.750.149', 'G07.100.100.160.120.186', 'G07.345.249.314.120.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G08.686.784.769'], ['C13.703'], ['G08.686.784.769.545'], ['E01.789'], ['I01.880.853.996.755', 'N0... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
"Quasi-REML" correlation estimates between production and health traits in the presence of selection and confounding: a simulation study. | Performance of the "quasi-REML" method for estimating correlations between a continuous trait and a categorical trait, and between two categorical traits, was studied with Monte Carlo simulations. Three continuous, correlated traits were simulated for identical populations and three scenarios with either no selection, ... | ['Animal Husbandry', 'Animals', 'Breeding', 'Models, Biological', 'Models, Statistical', 'Multifactorial Inheritance', 'Phenotype', 'Selection, Genetic'] | 10,229,350 | [['J01.040.090'], ['B01.050'], ['E05.820.150', 'G05.090'], ['E05.599.395'], ['E05.318.740.500', 'E05.599.835', 'N05.715.360.750.530', 'N06.850.520.830.500'], ['G05.420.590'], ['G05.695'], ['G05.783']] | ['Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Long-term weight change and breast cancer risk: the European prospective investigation into cancer and nutrition (EPIC). | We examined prospectively the association between weight change during adulthood and breast cancer risk, using data on 1358 incident cases that developed during 5.8 years of follow-up among 40,429 premenopausal and 57,923 postmenopausal women from six European countries, taking part in the European prospective investig... | ['Adult', 'Aged', 'Aged, 80 and over', 'Body Composition', 'Body Height', 'Body Mass Index', 'Breast Neoplasms', 'Cohort Studies', 'Europe', 'Female', 'Hormone Replacement Therapy', 'Humans', 'Incidence', 'Middle Aged', 'Nutritional Status', 'Postmenopause', 'Premenopause', 'Prospective Studies', 'Risk Factors', 'Weigh... | 16,136,032 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G02.111.130', 'G03.180', 'G07.100.049'], ['E01.370.600.115.100.160.100', 'E05.041.124.160.500', 'G07.100.100.160.100', 'G07.345.249.314.100'], ['E01.370.600.115.100.125', 'E05.041.124.125', 'G07.100.100.125', 'N06.850.505.200.100.175'], ['C04.588.180', '... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The two-component system CesRK controls the transcriptional induction of cell envelope-related genes in Listeria monocytogenes in response to cell wall-acting antibiotics. | The two-component system CesRK of Listeria monocytogenes responds to cell wall-acting antibiotics. We show here that CesRK controls the transcription of several cell envelope-related genes. The CesRK-dependent induction of these genes may be viewed as an attempt by L. monocytogenes to protect itself against the damagin... | ['Ampicillin', 'Anti-Bacterial Agents', 'Bacterial Proteins', 'Base Sequence', 'Cefuroxime', 'Cell Wall', 'Ethanol', 'Gene Expression Regulation, Bacterial', 'Listeria monocytogenes', 'Molecular Sequence Data', 'Mutation', 'Promoter Regions, Genetic', 'Protein Kinases', 'Sequence Homology, Amino Acid', 'Transcription F... | 18,456,805 | [['D02.065.589.099.750.750.050', 'D02.886.108.750.750.050', 'D03.633.100.300.750.750.050'], ['D27.505.954.122.085'], ['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['D02.065.589.099.249.188', 'D02.886.665.074.188', 'D03.633.100.300.249.188'], ['A11.284.183'], ['D02.033.375'], ['G05.308.300'... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
["Activity based costing" in radiology]. | BACKGROUND: The introduction of diagnosis related groups for reimbursement of hospital services in Germany (g-drg) demands for a reconsideration of utilization of radiological products and costs related to them.METHODS: Traditional cost accounting as approach to internal, department related budgets are compared with th... | ['Budgets', 'Costs and Cost Analysis', 'Diagnosis-Related Groups', 'Financial Management', 'Germany', 'Hospital Costs', 'Hospitals, University', 'Humans', 'Models, Economic', 'National Health Programs', 'Radiology Department, Hospital'] | 12,132,124 | [['N03.219.463.060'], ['N03.219.151'], ['N03.219.521.710.305.200.080'], ['N03.219.463'], ['Z01.542.315'], ['N03.219.151.400.687', 'N03.219.262.500', 'N05.300.375.500'], ['N02.278.020.300.310', 'N02.278.421.639.725'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.600', 'E05.599.835.890', 'N05.715.36... | ['Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Is there an association between intestinal perfusion and Crohn's disease activity? A feasibility study using contrast-enhanced ultrasound. | A recent study used contrast-enhanced ultrasound to assess splanchnic haemodynamics. This study investigates whether an association exists between disease activity and splanchnic transit time in patients with suspected Crohn's disease. The study protocol had the approval of the local ethics committee, and written infor... | ['Adult', 'Aged', 'Barium Sulfate', 'Blood Flow Velocity', 'Contrast Media', 'Crohn Disease', 'Epidemiologic Methods', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'Intestinal Mucosa', 'Intestine, Small', 'Male', 'Mesenteric Artery, Superior', 'Middle Aged', 'Phospholipids', 'Radiography', 'Splanchnic... | 18,955,414 | [['M01.060.116'], ['M01.060.116.100'], ['D01.103.075', 'D01.875.800.800.850.075'], ['E01.370.370.130', 'G09.330.380.630.080'], ['D27.505.259.500', 'D27.720.259'], ['C06.405.205.731.500', 'C06.405.469.432.500'], ['E05.318', 'N06.850.520'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Responses of hippocampal formation neurons in the monkey related to delayed spatial response and object-place memory tasks. | The memory for where in the environment a particular visual stimulus has been seen is one of the types of memory relatively specifically impaired by hippocampal damage in primates including man. In order to investigate what processing might be performed by the hippocampus related to this type of memory, the activity of... | ['Animals', 'Arousal', 'Attention', 'Brain Mapping', 'Conditioning, Operant', 'Discrimination Learning', 'Evoked Potentials', 'Form Perception', 'Hippocampus', 'Macaca mulatta', 'Memory', 'Memory, Short-Term', 'Mental Recall', 'Neurons', 'Orientation', 'Pattern Recognition, Visual', 'Psychomotor Performance', 'Reaction... | 2,757,782 | [['B01.050'], ['F02.830.104', 'G11.561.035'], ['F02.830.104.214'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['F02.463.425.179.509'], ['F02.463.425.280'], ['G07.265.216.500', 'G11.561.200.500'], ['F02.463.593.373', 'F02.463.593.778.435'], ['A08.186.211.180.405', 'A08.186.211.200.885.287... | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A negative role of SHP-2 tyrosine phosphatase in growth factor-dependent hematopoietic cell survival. | SHP-2 tyrosine phosphatase is highly expressed in hematopoietic cells; however, the function of SHP-2 in hematopoietic cell processes is not fully understood. Recent identification of SHP-2 mutations in childhood leukemia further emphasizes the importance of SHP-2 regulation in hematopoietic cells. We previously report... | ['Animals', 'Bone Marrow Cells', 'Cell Survival', 'DNA-Binding Proteins', 'Enzyme Activation', 'Growth Substances', 'Hematopoiesis', 'Hematopoietic Stem Cells', 'Intracellular Signaling Peptides and Proteins', 'Janus Kinase 2', 'Mice', 'Milk Proteins', 'Phosphorylation', 'Protein Tyrosine Phosphatase, Non-Receptor Type... | 15,116,097 | [['B01.050'], ['A11.148', 'A15.378.316'], ['G04.346'], ['D12.776.260'], ['G02.111.263', 'G03.328'], ['D27.505.696.377'], ['G04.152.825', 'G09.188.343'], ['A11.148.378', 'A11.872.378', 'A15.378.316.378'], ['D12.644.360', 'D12.776.476'], ['D08.811.913.696.620.682.725.124.200', 'D12.776.476.393.200', 'D12.776.624.664.700.... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Structural insight into dynamic bypass of the major cisplatin-DNA adduct by Y-family polymerase Dpo4. | Y-family DNA polymerases bypass Pt-GG, the cisplatin-DNA double-base lesion, contributing to the cisplatin resistance in tumour cells. To reveal the mechanism, we determined three structures of the Y-family DNA polymerase, Dpo4, in complex with Pt-GG DNA. The crystallographic snapshots show three stages of lesion bypas... | ['Antineoplastic Agents', 'Archaeal Proteins', 'Catalytic Domain', 'Cell Survival', 'Cisplatin', 'Crystallography, X-Ray', 'DNA Adducts', 'DNA, Archaeal', 'DNA-Directed DNA Polymerase', 'Electrophoresis, Gel, Two-Dimensional', 'Gene Knockout Techniques', 'Models, Molecular', 'Protein Structure, Tertiary', 'Proteome', '... | 20,512,114 | [['D27.505.954.248'], ['D12.776.090'], ['G02.111.570.120.704', 'G02.111.570.820.709.275.750.188'], ['G04.346'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['E05.196.309.742.225'], ['D13.444.308.135', 'G05.200.104'], ['D13.444.308.180'], ['D08.811.913.696.445.308.300'], ['E05.196.401.250', 'E05.301.300.230'], ['E05.... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Live cell microscopy of DNA damage response in Saccharomyces cerevisiae. | Fluorescence microscopy of the DNA damage response in living cells stands out from many other DNA repair assays by its ability to monitor the response to individual DNA lesions in single cells. This is particularly true in yeast, where the frequency of spontaneous DNA lesions is relatively low compared to organisms wit... | ['Cell Survival', 'DNA Damage', 'DNA Repair', 'DNA, Fungal', 'Genetic Markers', 'Microscopy, Fluorescence', 'Recombination, Genetic', 'Saccharomyces cerevisiae', 'Time Factors'] | 22,941,621 | [['G04.346'], ['G05.200'], ['G02.111.222', 'G05.219'], ['D13.444.308.300'], ['D23.101.387', 'G05.695.450'], ['E01.370.350.515.458', 'E05.595.458'], ['G05.728'], ['B01.300.107.795.785.800', 'B01.300.930.705.655'], ['G01.910.857']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Spatial distribution, risk assessment and influence factors of terrestrial gamma radiation dose in China. | The current spatial distribution of the risk of terrestrial gamma radiation in China were investigated by using spatial interpolation. And the driving factors influence on the terrestrial gamma radiation dose (TGRD) distribution were identified using the geographic detector, a new statistical method based on the nonlin... | ['Background Radiation', 'China', 'Gamma Rays', 'Radiation Dosage', 'Radiation Monitoring', 'Risk Assessment', 'Soil Pollutants, Radioactive', 'Tibet'] | 32,892,899 | [['G01.750.750.115'], ['Z01.252.474.164'], ['G01.358.500.505.300', 'G01.750.250.300', 'G01.750.750.400'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['E05.799.638', 'N06.850.780.375.700', 'N06.850.810.370'], ['E05.318.740.600.800.715', 'N04.452.871.715', 'N05.715.360.750.625.700.690', 'N06.850.505.715', 'N06.85... | ['Phenomena and Processes [G]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
[Effect of Intermittent Aeration on Nitrogen Removal Efficiency in Vertical Subsurface Flow Constructed Wetland]. | One-stage vertical subsurface flow constructed wetlands (CWs) were used to treat effluent from grit chamber in municipal wastewater treatment plant. The CW was divided into aerobic zone and anoxic zone by means of raising the effluent level and installing a perforated pipe. Two parameters (the ratio of aeration time an... | ['Biological Oxygen Demand Analysis', 'Denitrification', 'Nitrogen', 'Waste Disposal, Fluid', 'Wetlands'] | 27,337,890 | [['N06.850.460.350.080.500', 'N06.850.780.375.349'], ['G02.111.587.250', 'G02.607.560.250', 'G16.500.768.249'], ['D01.268.604', 'D01.362.625'], ['N06.850.780.200.800.800.890', 'N06.850.860.510.900.600.900'], ['G16.500.275.157.812', 'N06.230.124.625']] | ['Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Pelvic floor muscle function in continent and stress urinary incontinent women using dynamometric measurements. | AIMS: To compare the pelvic floor muscle (PFM) function in continent and stress urinary incontinent women using dynamometric measurements.METHODS: Thirty continent women and 59 women suffering from stress urinary incontinence (SUI), aged between 21 and 44 and parous, participated in the study. An instrumented speculum ... | ['Adult', 'Female', 'Humans', 'Muscle Contraction', 'Muscle, Skeletal', 'Pelvic Floor', 'Physical Endurance', 'Pressure', 'Urinary Incontinence, Stress'] | 15,382,183 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494'], ['A02.633.567', 'A10.690.552.500'], ['A01.923.600.600', 'A02.633.567.050.750'], ['G11.427.680', 'I03.450.642.845.054.600'], ['G01.374.715'], ['C12.777.934.852.249', 'C13.351.968.934.814.500', 'C23.888.942.343.800.500']] | ['Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Distal embolization and proximal stent-graft deployment: a dual approach to endovascular treatment of ruptured superior gluteal artery aneurysm. | Aneurysmal disease of the hypogastric branches is rare; it may be life-threatening, and the treatment is often challenging. Herein, we report the case of an 81-year-old man with arterial hypertension, obesity, renal insufficiency, and psychiatric disorders who was emergently admitted for a symptomatic ruptured aneurysm... | ['Aged, 80 and over', 'Aneurysm, Ruptured', 'Blood Vessel Prosthesis Implantation', 'Buttocks', 'Cardiopulmonary Bypass', 'Embolization, Therapeutic', 'Humans', 'Magnetic Resonance Angiography', 'Male', 'Prostheses and Implants', 'Radiography', 'Stents'] | 18,427,653 | [['M01.060.116.100.080'], ['C14.907.055.185'], ['E04.100.814.868.500', 'E04.650.200'], ['A01.378.610.100'], ['E04.292.413'], ['E02.520.360', 'E02.926.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500.500', 'E01.370.370.050.500'], ['E07.695'], ['E01.370.350.700'], ['E07.695.750']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Experience of automation failures in training: effects on trust, automation bias, complacency and performance. | This work examined the effects of operators' exposure to various types of automation failures in training. Forty-five participants were trained for 3.5 h on a simulated process control environment. During training, participants either experienced a fully reliable, automatic fault repair facility (i.e. faults detected a... | ['Adolescent', 'Adult', 'Automation', 'Bias', 'Equipment Failure', 'Female', 'Humans', 'Male', 'Man-Machine Systems', 'Trust', 'Young Adult'] | 26,374,396 | [['M01.060.057'], ['M01.060.116'], ['J01.897.104'], ['N05.715.350.150', 'N06.850.490.500'], ['E05.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.784.412.575', 'J01.293.556.441', 'J01.897.441'], ['F01.829.401.825'], ['M01.060.116.815']] | ['Named Groups [M]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
PIPI: PTM-Invariant Peptide Identification Using Coding Method. | In computational proteomics, the identification of peptides with an unlimited number of post-translational modification (PTM) types is a challenging task. The computational cost associated with database search increases exponentially with respect to the number of modified amino acids and linearly with respect to the nu... | ['Algorithms', 'Amino Acid Sequence', 'Animals', 'Computational Biology', 'Computer Simulation', 'Databases, Protein', 'Humans', 'Protein Processing, Post-Translational', 'Proteomics', 'Software'] | 27,748,123 | [['G17.035', 'L01.224.050'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['H01.158.273.180', 'L01.313.124'], ['L01.224.160'], ['L01.313.500.750.300.188.400.300.750', 'L01.313.500.750.300.188.400.325.710', 'L01.470.750.750.300.750', 'L01.470.750.750.325.710'], ['B01.050.150.900.649.313.988.400.112.400.400']... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Dynamic osteosynthesis with angled flexible nails in recent fractures of the diaphysis of the tibia. | Dynamic osteosynthesis with curved flexible nails was introduced by Burghele for the treatment of recent fractures of the diaphysis of the tibia. Our experience in sixty patients has shown that this method of treatment produces better results than rigid AO osteosynthesis and also than osteosynthesis with rigid Kuntsche... | ['Bone Nails', 'Fracture Fixation, Intramedullary', 'Humans', 'Tibial Fractures'] | 7,152,883 | [['E07.695.370.249', 'E07.858.442.660.460.249', 'E07.858.690.725.460.249'], ['E04.555.300.300.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C26.404.875', 'C26.558.857']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Immune recognition of Ornithodoros tick (Acari: Argasidae) salivary antigens by anti-Psoroptes cuniculi antibodies. | Rabbits infested with either Ornithodoros sp. ticks or Psoroptes cuniculi mites were assayed for anti-tick antibody by enzyme-linked immunosorbent assay. Titration of rabbit serum against Ornithodoros sp. salivary gland extract (SGE) demonstrated both mite- and tick-infested animals to have elevated anti-tick antibody ... | ['Animals', 'Antibodies', 'Antigens', 'Blotting, Western', 'Cross Reactions', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Immune Sera', 'Mites', 'Rabbits', 'Salivary Glands', 'Ticks'] | 8,604,125 | [['B01.050'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D23.050'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['G12.122.281'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170',... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effect of internal hexagonal index on removal torque and tensile removal force of different Morse taper connection abutments. | STATEMENT OF PROBLEM: The maintenance of the mechanical stability of implant-abutment connections is relevant to the clinical success of implant-supported restorations. However, the reduction in the conical area of abutments with an internal hexagonal index may result in a biomechanical disadvantage in Morse taper conn... | ['Biomechanical Phenomena', 'Dental Abutments', 'Dental Implant-Abutment Design', 'Dental Implants', 'Dental Stress Analysis', 'Device Removal', 'In Vitro Techniques', 'Materials Testing', 'Stress, Mechanical', 'Surface Properties', 'Tensile Strength', 'Torque'] | 27,881,313 | [['G01.154.090', 'G01.374.089'], ['E06.780.346.500', 'E07.695.190.175'], ['E06.780.346.625.500', 'E06.912.145.750'], ['D25.339.312', 'E06.780.346.593', 'E07.695.185', 'J01.637.051.339.312'], ['E06.308'], ['E04.199'], ['E05.481'], ['E05.570'], ['G01.374.835'], ['G02.860'], ['G01.374.850'], ['G01.374.860.500']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Management of left atrial endocardium after extensive thrombectomy. | Thrombosis at the left atrium is a common phenomenon in patients with chronic mitral valve disease and atrial fibrillation. When thrombus organizes and evolves into chronic phase, clean thrombectomy can become a challenge during heart surgery because of dense adhesions and the lack of clean cleavage plane. Leaving resi... | ['Atrial Appendage', 'Atrial Fibrillation', 'Chronic Disease', 'Fibrosis', 'Heart Atria', 'Heart Diseases', 'Heart Valve Prosthesis Implantation', 'Humans', 'Male', 'Middle Aged', 'Mitral Valve Insufficiency', 'Mitral Valve Stenosis', 'Pericardium', 'Postoperative Complications', 'Pulmonary Edema', 'Rheumatic Heart Dis... | 15,620,901 | [['A07.541.358.100'], ['C14.280.067.198', 'C23.550.073.198'], ['C23.550.291.500'], ['C23.550.355'], ['A07.541.358'], ['C14.280'], ['E04.100.376.485', 'E04.650.410', 'E04.928.220.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.484.461'], ['C14.280.484.517'], ['A07.541.795', 'A10.61... | ['Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A computational study of the effect of intraglottal vortex-induced negative pressure on vocal fold vibration. | Recent studies reported the formation of intraglottal vortices for medium and high subglottal pressures in excised-larynx experiments, and hypothesized that the suction force created by these vortices might affect vocal fold vibration. However, high subglottal pressures often lead to large vocal fold elastic recoil for... | ['Air Pressure', 'Computer Simulation', 'Elasticity', 'Glottis', 'Humans', 'Phonation', 'Vacuum', 'Vibration', 'Vocal Cords'] | 25,373,995 | [['G16.500.750.274.100', 'N06.230.300.100.185.100'], ['L01.224.160'], ['G01.374.590'], ['A04.329.364'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G09.772.585'], ['G01.374.715.902', 'G16.500.750.274.902', 'N06.230.300.100.185.902'], ['G01.374.930'], ['A04.329.364.737']] | ['Phenomena and Processes [G]', 'Health Care [N]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Morell Mackenzie and Crown Prince Frederick: an unpublished manuscript from the Royal Society of Medicine Library. | The story of Morell Mackenzie and his involvement in the case of Crown Prince Frederick III (the future Emperor of Germany) is as well known as it is controversial. The consequences of the case were profound, both medically and politically. Most documents concerning the case are affected by varying degrees of bias, and... | ['Dysphonia', 'Famous Persons', 'Germany', 'History, 19th Century', 'Laryngeal Neoplasms', 'Manuscripts as Topic', 'Papilloma', 'Vocal Cords'] | 18,761,761 | [['C08.360.940.325', 'C09.400.940.325', 'C10.597.975.325', 'C23.888.592.979.325'], ['K01.517.211.506', 'M01.228'], ['Z01.542.315'], ['K01.400.504.937'], ['C04.588.443.665.481', 'C08.360.369', 'C08.785.481', 'C09.400.369', 'C09.647.481'], ['L01.178.682.608'], ['C04.557.470.700.600'], ['A04.329.364.737']] | ['Diseases [C]', 'Humanities [K]', 'Named Groups [M]', 'Geographicals [Z]', 'Information Science [L]', 'Anatomy [A]'] | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 1 |
Quantitative risk assessment in relation to occupational exposure to polychlorinated biphenyls in the removal of old sealants from buildings. | OBJECTIVES: The objectives of the study were to assess exposure to polychlorinated biphenyls (PCB) among workers involved in the removal of old sealants containing PCB and to evaluate the related long-term health risks by means of quantitative risk assessment.METHODS: Workers' exposure via different exposure routes was... | ['Evaluation Studies as Topic', 'Facility Design and Construction', 'Finland', 'Humans', 'Inhalation Exposure', 'Neoplasms', 'Occupational Exposure', 'Polychlorinated Biphenyls', 'Reference Standards', 'Risk Assessment'] | 16,363,446 | [['E05.337', 'N05.715.360.335'], ['J01.086.339', 'N02.278.200'], ['Z01.542.816.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N06.850.460.350.112'], ['C04'], ['N06.850.460.350.600'], ['D02.309.750', 'D02.455.426.559.389.185.698', 'D02.455.526.439.773'], ['E05.978.808'], ['E05.318.740.600.800.715', 'N04.452.8... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 |
DNA-Assisted Dispersion of Carbon Nanotubes and Comparison with Other Dispersing Agents. | Separation and sorting of pristine carbon nanotubes (CNTs) from bundle geometry is a very challenging task due to the insoluble and nondispersive nature of CNTs in aqueous medium. Recently, many studies have been performed to address this problem using various organic and inorganic solutions, surfactant molecules, and ... | ['DNA, Single-Stranded', 'Molecular Dynamics Simulation', 'Nanotubes, Carbon', 'Surface-Active Agents'] | 28,905,626 | [['D13.444.308.497', 'G02.111.570.820.486.437', 'G05.360.580.437'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['D01.268.150.250.500', 'J01.637.512.850.500'], ['D27.720.877']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
[Juvenile xanthogranuloma of the nasal cavity]. | JXG is a benign lesion of unknown incidence. It is the most frequent type of non-langerhans histiocytosis with a median age of 2 years. It usually presents as isolated cutaneous lesions. Multiple lesions, especially over the head and neck, may occur. The skin lesions tend to regress slowly with time. Extra-cutaneous an... | ['Child', 'Female', 'Humans', 'Nasal Cavity', 'Nose Diseases', 'Xanthogranuloma, Juvenile'] | 21,055,524 | [['M01.060.406'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A04.531.449'], ['C08.460', 'C09.603'], ['C15.604.250.410.900', 'C17.800.973']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Anaesthetic management of brain-dead for organ donation: impact on delayed graft function after kidney transplantation]. | BACKGROUND: The aim of this study was to report current anaesthetic management brain-dead organ donors and to assess its impact on delayed kidney graft function (DGF).METHODS: To achieve this retrospective multicenter study, brain-dead patient records were analysed for the years 2005 to 2007. Expanded donor criteria, l... | ['Adult', 'Aged', 'Anesthesia', 'Blood Pressure', 'Brain Death', 'Delayed Graft Function', 'Electroencephalography', 'Female', 'France', 'Heart Rate', 'Hemodynamics', 'Humans', 'Hydroxyethyl Starch Derivatives', 'Ischemia', 'Kidney Transplantation', 'Male', 'Middle Aged', 'Plasma Substitutes', 'Respiration, Artificial'... | 22,541,983 | [['M01.060.116'], ['M01.060.116.100'], ['E03.155'], ['E01.370.600.875.249', 'G09.330.380.076'], ['C10.228.140.151', 'C10.597.606.358.800.200.100', 'C23.550.260.159'], ['C23.550.277'], ['E01.370.376.300', 'E01.370.405.245'], ['Z01.542.286'], ['E01.370.600.875.500', 'G09.330.380.500'], ['G09.330.380'], ['B01.050.150.900.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Geographicals [Z]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
[5'-methylthioadenosine phosphorylase from Caldariella acidophila. 1. Purification and partial characterization]. | 5'-Methylthioadenosine phosphorylase has been isolated from C.acidophila, a thermophilic bacterium living in acid hot springs at temperatures ranging from 63 to 89 degrees C. The enzyme has been purified to homogeneity in 32% yield. The enzyme shows a high degree of thermophilicity, its temperature optimum being 93 deg... | ['Adenosine', 'Bacteria', 'Chemical Precipitation', 'Hot Temperature', 'Hydrogen-Ion Concentration', 'Indicators and Reagents', 'Kinetics', 'Pentosyltransferases', 'Purine-Nucleoside Phosphorylase', 'Thionucleosides'] | 41,533 | [['D03.633.100.759.590.138', 'D13.570.583.138', 'D13.570.800.096'], ['B03'], ['E05.196.150', 'G02.159'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['G02.300'], ['D27.720.470.410'], ['G01.374.661', 'G02.111.490'], ['D08.811.91... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Toward Multiscale Modeling of Proteins and Bioagglomerates: An Orientation-Sensitive Diffusion Model for the Integration of Molecular Dynamics and the Discrete Element Method. | Most processes involved in biological and biotechnological systems spread over many scales in space and time. For example, the interaction of multiple enzymes in heterogeneous enzymatic agglomerates or clusters, necessary for efficient enzymatic conversion, is of high interest for research and enzyme engineering. In or... | ['Diffusion', 'Molecular Dynamics Simulation', 'Protein Conformation', 'Proteins', 'Rotation', 'Solvents'] | 30,550,276 | [['G01.202', 'G02.196'], ['E05.599.595.500', 'G02.111.570.895', 'L01.224.160.500'], ['G02.111.570.820.709'], ['D12.776'], ['G01.482.703'], ['D27.720.844']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Physico-chemical properties of cationic niosomes loaded with fraction of rice (Oryza sativa) bran extract. | The aim of this study was to investigate the physico-chemical properties of cationic niosomes (Tween61/cholesterol/CTAB) loaded with fraction No. 3 of Oryza sativa bran extract (OSF3) at 0.1, 0.5, 1.0 and 2.0% (w/v), respectively, before and after ultra-centrifugation. More white milky translucent appearance of the nio... | ['Cations', 'Hot Temperature', 'Microscopy, Electron, Transmission', 'Oryza', 'Particle Size', 'Plant Extracts', 'Scattering, Small Angle', 'Ultracentrifugation', 'Viscosity', 'X-Ray Diffraction'] | 23,035,474 | [['D01.248.497.300'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['E01.370.350.515.402.580', 'E05.595.402.580'], ['B01.650.940.800.575.912.250.822.616'], ['G02.712'], ['D20.215.784.500', 'D26.667'], ['E05.196.822.830', 'G01.86... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Rapid adaptation of phytoplankters to geothermal waters is achieved by single mutations: were extreme environments 'Noah's Arks' for photosynthesizers during the Neoproterozoic 'snowball Earth'? | Geothermal waters often support remarkable communities of microalgae and cyanobacteria apparently living at the extreme limits of their tolerance. Little is known about the mechanisms allowing adaptation of mesophilic phytoplankters to such extreme conditions, but recent studies are challenging many preconceived notion... | ['Adaptation, Biological', 'Chlorophyta', 'Ecosystem', 'Evolution, Molecular', 'Fresh Water', 'Hot Springs', 'Ice Cover', 'Microcystis', 'Mutation', 'Phytoplankton', 'Selection, Genetic', 'Stress, Physiological'] | 18,803,596 | [['G16.012'], ['B01.650.940.150'], ['G16.500.275.157', 'N06.230.124'], ['G05.045.250', 'G16.075.250'], ['G16.500.275.280', 'N06.230.232'], ['G01.311.355.750.500', 'G16.500.275.260.500'], ['G01.311.400', 'G16.500.275.410.500', 'N06.230.291.500'], ['B03.280.500', 'B03.440.475.100.500'], ['G05.365.590'], ['B05.080.500.600... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Effect of surface treatments on the bond strength of veneering ceramic to zirconia. | AIM: The purpose of this study was to evaluate the effect of different surface treatments on the bond strength of veneering ceramic to zirconia.METHODS: Square (15 mm x 10 mm x 2 mm) zirconia specimens (n=18) received one of the following surface treatments: Group 1, sandblasting; Group 2, Clearfil ceramic primer appli... | ['Ceramics', 'Coated Materials, Biocompatible', 'Zirconium'] | 24,700,261 | [['J01.637.153'], ['D25.130.420', 'J01.637.051.130.420'], ['D01.268.556.950', 'D01.268.956.937', 'D01.552.544.950']] | ['Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Fix and forget or fix and report: a qualitative study of tensions at the front line of incident reporting. | INTRODUCTION: Practitioners frequently encounter safety problems that they themselves can resolve on the spot. We ask: when faced with such a problem, do practitioners fix it in the moment and forget about it, or do they fix it in the moment and report it? We consider factors underlying these two approaches.METHODS: We... | ['Health Personnel', 'Humans', 'Interviews as Topic', 'Medical Errors', 'Ontario', 'Patient Safety', 'Qualitative Research', 'Quality of Health Care', 'Risk Management', 'Safety Management', 'Tertiary Care Centers'] | 25,749,025 | [['M01.526.485', 'N02.360'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.420', 'L01.399.250.520', 'N05.715.360.300.400', 'N06.850.520.308.420'], ['N02.421.450'], ['Z01.107.567.176.639'], ['N06.850.135.060.075.399'], ['H01.770.644.241.850'], ['N04.761', 'N05.715'], ['N03.219.463.800', 'N04.452.871'], ... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Geographicals [Z]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 |
Neonatal short bowel syndrome: population-based estimates of incidence and mortality rates. | BACKGROUND: Congenital or acquired neonatal short bowel syndrome (SBS) carries significant morbidity and mortality rates. No accurate population estimates of incidence and mortality exist because of differences in definition, follow-up, and regional referral patterns.METHODS: A retrospective cohort study was performed ... | ['Cohort Studies', 'Female', 'Humans', 'Incidence', 'Infant, Newborn', 'Male', 'Ontario', 'Retrospective Studies', 'Risk', 'Short Bowel Syndrome'] | 15,137,001 | [['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.308.985.525.375', 'N01.224.935.597.500', 'N06.850.505.400.975.525.375', 'N06.850.520.308.985.525.375'], ['M01.060.703.520'], ['Z01.107.567.176.639'], ['E05.318.372.500.500.500', 'E0... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Named Groups [M]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Prediabetes in pregnancy, can early intervention improve outcomes? A feasibility study for a parallel randomised clinical trial. | OBJECTIVE: Measurement of glycated haemoglobin (HbA1c) in early pregnancy is routine in New Zealand to identify women with diabetes and prediabetes. However, the benefit of early intervention in women with prediabetes is inconclusive. Our aim was to test the feasibility of a two-arm parallel randomised controlled trial... | ['Adult', 'Blood Glucose Self-Monitoring', 'Cesarean Section', 'Early Medical Intervention', 'Feasibility Studies', 'Female', 'Gestational Age', 'Glucose Tolerance Test', 'Glycated Hemoglobin A', 'Humans', 'Life Style', 'New Zealand', 'Patient Compliance', 'Pre-Eclampsia', 'Prediabetic State', 'Pregnancy', 'Pregnancy C... | 29,502,087 | [['M01.060.116'], ['E01.370.225.124.100.105', 'E01.370.374.100', 'E01.370.520.100', 'E02.900.950.500', 'E05.200.124.100.105'], ['E04.520.252.500'], ['N02.421.726.363'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['G07.345.500.325.235.968', 'G08.686.320'], ['E01.370.225.124.100.355... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The Effectiveness of Dietary Approaches to Stop Hypertension Diet Intervention in Persons with Arterial Hypertension and Obesity: A Key Role of the Patients' Personality Profile. | BACKGROUND/AIMS: Benefits resulting from weight loss and dietary approaches to stop hypertension (DASH) diet in the treatment of arterial hypertension led to a search for a better therapy that would include psychological factors. The present study aimed to assess the relationship between the personality traits included... | ['Aged', 'Dietary Approaches To Stop Hypertension', 'Essential Hypertension', 'Female', 'Humans', 'Male', 'Middle Aged', 'Obesity', 'Overweight', 'Personality', 'Weight Loss'] | 29,353,281 | [['M01.060.116.100'], ['E02.642.249.475', 'G07.203.650.240.325'], ['C14.907.489.165'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C18.654.726.500', 'C23.888.144.699.500', 'E01.370.600.115.100.160.120.699.500', 'G07.100.100.160.120.699.500'], ['C23.888.144.699', 'E01.370.600.115.100.160.120.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Arabidopsis CYP85A2 catalyzes lactonization reactions in the biosynthesis of 2-deoxy-7-oxalactone brassinosteroids. | Brassinolide (BL), a plant 7-oxalactone-type steroid hormone, is one of the active brassinosteroids (BRs) that regulates plant growth and development. BL is biosynthesized from castasterone by the cytochrome P450 monooxygenase, CYP85A2. We showed that a Pichia pastoris transformant that synchronously expresses Arabidop... | ['Arabidopsis', 'Arabidopsis Proteins', 'Catalysis', 'Cytochrome P-450 Enzyme System', 'Gas Chromatography-Mass Spectrometry', 'Lactones', 'Molecular Structure', 'Pichia', 'Proto-Oncogene Proteins c-myb', 'Recombinant Proteins', 'Steroids', 'Transgenes'] | 18,685,225 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G02.130'], ['D08.244.453', 'D08.811.682.690.708.170', 'D12.776.422.220.453'], ['E05.196.181.349.500', 'E05.196.566.500'], ['D02.540'], ['G02.111.570', 'G02.466'], ['B01.300.107.795.700', 'B01.300.930.600'], ['D12.776.260.675', 'D12.776.624.664.700.188', '... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Changes in serum copper and zinc during treatment with anticancer drugs interfering with pyridoxal phosphate. | Hexamethylmelamine, pentamethylmelamine and procarbazine are anticancer drugs known to interfere with pyridoxal phosphate. This paper presents results on copper and zinc serum levels during the treatment with each of these drugs used as single agents. Six NZW rabbits weighing 2.7-4.5 kg were used in these experiments. ... | ['Altretamine', 'Animals', 'Antineoplastic Agents', 'Coenzymes', 'Copper', 'Male', 'Procarbazine', 'Pyridoxal Phosphate', 'Rabbits', 'Triazines', 'Zinc'] | 2,516,708 | [['D03.383.931.135'], ['B01.050'], ['D27.505.954.248'], ['D08.211'], ['D01.268.556.195', 'D01.268.956.170', 'D01.552.544.195'], ['D02.065.277.727', 'D02.241.223.100.100.655', 'D02.455.426.559.389.127.085.655'], ['D03.383.725.676.925.500.500', 'D08.211.740'], ['B01.050.150.900.649.313.968.700'], ['D03.383.931'], ['D01.2... | ['Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Using the Dempster-Shafer theory of evidence with a revised lattice structure for activity recognition. | This paper explores a sensor fusion method applied within smart homes used for the purposes of monitoring human activities in addition to managing uncertainty in sensor-based readings. A three-layer lattice structure has been proposed, which can be used to combine the mass functions derived from sensors along with sens... | ['Activities of Daily Living', 'Algorithms', 'Computer Communication Networks', 'Home Care Services', 'Humans', 'Models, Theoretical', 'Monitoring, Ambulatory', 'Pattern Recognition, Automated', 'Toilet Facilities'] | 21,075,728 | [['E02.760.169.063.500.067', 'E02.831.067', 'I03.050', 'N02.421.784.110'], ['G17.035', 'L01.224.050'], ['L01.224.230.110'], ['N02.421.143.524', 'N02.421.539.089'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599'], ['E01.370.520.500'], ['L01.399.750'], ['J03.962', 'N06.850.780.200.800.800.795', 'N06.850.860.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 |
Endothelial dysfunction and intima media thickness are selectively related to the different carbohydrate disturbances across the glucose continuum. | Aim: The aim of the present study was to investigate the prevalence of macrovascular complications across different carbohydrate disturbances. Patients and methods: In the study, we included 167 patients, divided them into three age and BMI matched groups - group 1 with obesity without carbohydrate disturbances (n = 66... | ['Adult', 'Aged', 'Carotid Intima-Media Thickness', 'Diabetes Mellitus, Type 2', 'Endothelium, Vascular', 'Female', 'Glucose', 'Humans', 'Male', 'Middle Aged'] | 29,882,429 | [['M01.060.116'], ['M01.060.116.100'], ['E01.370.350.850.150', 'E01.370.370.180', 'G09.330.210'], ['C18.452.394.750.149', 'C19.246.300'], ['A07.015.700.500', 'A10.272.491.355'], ['D09.947.875.359.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Intentionally induced intestinal barrier dysfunction causes inflammation, affects metabolism, and reduces productivity in lactating Holstein cows. | Study objectives were to evaluate the effects of intentionally reduced intestinal barrier function on productivity, metabolism, and inflammatory indices in otherwise healthy dairy cows. Fourteen lactating Holstein cows (parity 2.6 ± 0.3; 117 ± 18 d in milk) were enrolled in 2 experimental periods. Period 1 (5 d) served... | ['3-Hydroxybutyric Acid', 'Animal Feed', 'Animals', 'Cattle', 'Diet', 'Fatty Acids, Nonesterified', 'Female', 'Gastrointestinal Tract', 'Inflammation', 'Lactation', 'Milk'] | 28,342,610 | [['D02.241.081.114.937.349', 'D02.241.511.429.349', 'D02.522.585.087', 'D10.251.400.143.781.500'], ['G07.203.300.300.100', 'J02.500.300.100'], ['B01.050'], ['B01.050.150.900.649.313.500.380.271'], ['G07.203.650.240'], ['D10.251.310'], ['A03.556'], ['C23.550.470'], ['G08.686.523', 'G08.686.702.500'], ['A12.200.455', 'A1... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A new experimental model for microanastomosis between vessels of different diameter. | A new model for microvascular anastomosis between vessels of different diameter is described in the aorto-iliac region of the rat. The model consists of reversing the distal end of one iliac artery toward the aorta to perform an end-to-end or end-to-side microanastomosis, with 2:1 diameter ratio. The technique and the ... | ['Animals', 'Aorta', 'Iliac Artery', 'Microsurgery', 'Models, Biological', 'Rats', 'Vascular Surgical Procedures'] | 4,058,299 | [['B01.050'], ['A07.015.114.056'], ['A07.015.114.444'], ['E04.494', 'E05.591.580'], ['E05.599.395'], ['B01.050.150.900.649.313.992.635.505.700'], ['E04.100.814']] | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A Circadian and Cardiac Intraocular Pressure Sensor for Smart Implantable Lens. | This paper presents a new system to measure the Intraocular Pressure (IOP) with very high accuracy (0.036 mbar) used for monitoring glaucoma. The system not only monitors the daily variation of the IOP (circadian IOP), but also allows to perform an spectral analysis of the pressure signal generated by the heartbeat (ca... | ['Biosensing Techniques', 'Circadian Rhythm', 'Glaucoma', 'Humans', 'Intraocular Pressure', 'Lenses, Intraocular', 'Mobile Applications', 'Monitoring, Ambulatory', 'Remote Sensing Technology', 'Tonometry, Ocular'] | 26,800,549 | [['E05.601.043'], ['G07.180.562.190'], ['C11.525.381'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G14.440'], ['E07.632.500.460', 'E07.695.460'], ['L01.224.900.685'], ['E01.370.520.500'], ['E01.370.520.750.500', 'E05.925.500', 'L01.178.847.675.500'], ['E01.370.380.750']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Information Science [L]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Chronic inhibition of NOS-2 ameliorates renal injury, as well as COX-2 and TGF-beta 1 overexpression in 5/6 nephrectomized rats. | BACKGROUND: Chronic renal damage is associated with inflammatory infiltration, fibrosis and vascular lesion, coupled with increased expression of cyclo-oxygenase 2 (COX-2) and transforming growth factor-beta1 (TGF-beta1). However, the role of inducible nitric oxide synthase (NOS-2) is still controversial. Thus, we stud... | ['Animals', 'Cyclooxygenase 2', 'Kidney Cortex', 'Ligation', 'Male', 'Nephrectomy', 'Nitric Oxide', 'Nitric Oxide Synthase Type II', 'Rats', 'Rats, Sprague-Dawley', 'Renal Artery', 'Transforming Growth Factor beta1'] | 16,935,907 | [['B01.050'], ['D08.811.600.720.750'], ['A05.810.453.324'], ['E04.426'], ['E04.950.774.435'], ['D01.339.387', 'D01.625.550.500', 'D01.625.700.500', 'D01.650.550.587.600'], ['D08.811.682.664.500.772.500', 'D12.776.157.687.575', 'D12.776.660.720.575'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.31... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Anti-TGF-beta treatment prevents skin and lung fibrosis in murine sclerodermatous graft-versus-host disease: a model for human scleroderma. | Scleroderma, a debilitating acquired connective tissue disease, is characterized by fibrosis, particularly of the skin and lungs. Monocyte-produced TGF-beta1, a potent stimulus for collagen synthesis, is thought to drive the fibrosis. Here, we thoroughly characterize a murine sclerodermatous graft-vs-host disease (Scl ... | ['Animals', 'Bone Marrow Transplantation', 'Cell Movement', 'Collagen', 'Disease Models, Animal', 'Female', 'Fibrosis', 'Graft vs Host Disease', 'Immune Sera', 'Injections, Intravenous', 'Leukocytes, Mononuclear', 'Macrophage-1 Antigen', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C57BL', 'Pulmonary Fibrosis', 'RNA, M... | 10,553,100 | [['B01.050'], ['E02.095.147.725.040', 'E04.936.580.040'], ['G04.198', 'G07.568.500.180'], ['D05.750.078.280', 'D12.776.860.300.250'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.550.355'], ['C20.452'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', 'D12.776.377.715.548.11... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Smoking habit and bronchial reactivity in normal subjects. A population-based study. | The relationship between smoking habits and airway responsiveness has been studied in a cross-sectional sample of subjects in a small Lombardy (Italy) town. The subjects were between 15 and 64 yr of age; they were representative of the general population. There were 295 normal nonsmokers, 70 normal smokers, and 50 past... | ['Adolescent', 'Adult', 'Bronchi', 'Bronchial Provocation Tests', 'Cross-Sectional Studies', 'Female', 'Forced Expiratory Volume', 'Humans', 'Italy', 'Lung Diseases, Obstructive', 'Male', 'Methacholine Chloride', 'Methacholine Compounds', 'Middle Aged', 'Regression Analysis', 'Smoking'] | 2,665,586 | [['M01.060.057'], ['M01.060.116'], ['A04.411.125'], ['E01.370.386.700.125'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['E01.370.386.700.660.230', 'G09.772.650.430'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['C08.381.495'], ['D02.092.877.883.555.500', 'D02.... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
MR imaging of olfactory bulbs and tracts. | Olfactory bulbs are easily detected on coronal T1-weighted MR images. They are situated almost symmetrically opposite either side of the lower end of the olfactory sulci, and, on sagittal images, they are observed as thin soft-tissue bands immediately beneath the frontal lobe base. On axial images they are shown as ova... | ['Humans', 'Magnetic Resonance Imaging', 'Olfactory Bulb', 'Olfactory Nerve'] | 2,505,540 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['A08.186.211.200.885.388'], ['A08.800.800.120.640']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Surgical correction of 34 patients with hypertelorism]. | In 34 patients with hypertelorism aged on the average 12.6 years, 24 underwent intracranial surgery (combined intra- and extracranial approach), 2 (moderate) U-osteotomy (subcranial approach), and 8 (mild) canthoplasties. Improved results were obtained in the patients with various types of hypertelorism. The complicati... | ['Adolescent', 'Adult', 'Blood Loss, Surgical', 'Child', 'Child, Preschool', 'Craniofacial Dysostosis', 'Craniotomy', 'Female', 'Hemostasis, Surgical', 'Humans', 'Hypertelorism', 'Intracranial Pressure', 'Male', 'Postoperative Complications'] | 1,473,404 | [['M01.060.057'], ['M01.060.116'], ['C23.550.414.300', 'C23.550.505.300'], ['M01.060.406'], ['M01.060.406.448'], ['C05.116.099.370.231', 'C05.660.207.231', 'C16.131.621.207.231'], ['E04.525.190'], ['E02.520.490', 'E04.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.116.099.370.231.480', 'C05.660.207.231.4... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Intracellular determination of activated caspases (IDAC) by flow cytometry using a pancaspase inhibitor labeled with FITC. | BACKGROUND: Flow cytometry-based methods of simultaneous detection of multiple activated caspases in single cells are of diagnostic value and remain to be fully explored.METHODS: Genomic DNA fragmentation was determined by agarose gel electrophoresis and flow cytometry. Whole cells were incubated with the cell-permeabl... | ['Amino Acid Chloromethyl Ketones', 'Apoptosis', 'Caspase Inhibitors', 'Caspases', 'Cell Survival', 'DNA Fragmentation', 'DNA, Neoplasm', 'Dose-Response Relationship, Drug', 'Electrophoresis, Agar Gel', 'Enzyme Inhibitors', 'Flow Cytometry', 'Fluorescein-5-isothiocyanate', 'Humans', 'Jurkat Cells', 'Propidium'] | 14,608,638 | [['D12.125.065'], ['G04.146.954.035'], ['D27.505.519.389.745.325.500'], ['D08.811.277.656.262.500.126', 'D08.811.277.656.300.200.126', 'D12.644.360.075.405', 'D12.776.476.075.405'], ['G04.346'], ['G05.200.230'], ['D13.444.308.425'], ['G07.690.773.875', 'G07.690.936.500'], ['E05.196.401.153', 'E05.301.300.100'], ['D27.5... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The skin-tightening effects of 1,444-nm Nd:YAG laser on human skin: an in vivo study. | BACKGROUND: The 1,444-nm Nd:YAG laser was developed to improve the removal of fat cells and to affect the underlying dermis with the aim of skin tightening. We conducted this study to evaluate whether this laser is effective in tightening the skin and causing histological alterations to dermal collagen fibers, fibrobla... | ['Adult', 'Dermis', 'Female', 'Humans', 'Lasers, Solid-State', 'Skin'] | 24,788,857 | [['M01.060.116'], ['A17.815.180'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.632.490.490', 'E07.710.520.490'], ['A17.815']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Burst-promoting activity (BPA) without erythropoietin (Ep) activity in sera of aplastic anemia patients fractionated by chromatofocusing column. | A chromatofocusing column was used to separate burst-promoting activity (BPA) and erythropoietin (Ep) activity in sera from patients with aplastic anemia and, interestingly a fraction containing a considerable level of BPA without Ep activity was found at around pH 5.0. Another fraction at lower pH contained both activ... | ['Anemia, Aplastic', 'Animals', 'Bone Marrow Cells', 'Cell Line', 'Chromatography, Gel', 'Culture Media', 'Erythropoiesis', 'Erythropoietin', 'Female', 'Humans', 'Isoelectric Focusing', 'Leukemia, Experimental', 'Lymphocyte Activation', 'Mice', 'Mice, Inbred C57BL', 'Molecular Weight', 'Pregnancy'] | 7,151,897 | [['C15.378.071.085', 'C15.378.190.223.250'], ['B01.050'], ['A11.148', 'A15.378.316'], ['A11.251.210'], ['E05.196.181.400.250'], ['D27.720.470.305', 'E07.206'], ['G04.152.825.414', 'G09.188.343.414'], ['D12.644.276.374.410.240.150', 'D12.776.395.240.150', 'D12.776.467.374.410.240.150', 'D23.529.374.410.240.150'], ['B01.... | ['Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Value of transcatheter arterial embolization with coils and n-butyl cyanoacrylate for long-term hepatic arterial infusion chemotherapy. | PURPOSE: To assess the value of transcatheter arterial embolization (TAE) of splanchnic arterial branches to allow continuous application of repeat hepatic arterial infusion chemotherapy (HAIC).MATERIALS AND METHODS: In 128 patients with unresectable advanced liver cancer, percutaneous implantation of a port catheter s... | ['Adult', 'Aged', 'Aged, 80 and over', 'Angiography', 'Catheters, Indwelling', 'Embolization, Therapeutic', 'Enbucrilate', 'Female', 'Hepatic Artery', 'Humans', 'Infusions, Intra-Arterial', 'Liver', 'Liver Neoplasms', 'Long-Term Care', 'Male', 'Middle Aged', 'Splanchnic Circulation'] | 14,739,309 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E01.370.350.700.060', 'E01.370.370.050'], ['E07.132.500'], ['E02.520.360', 'E02.926.500'], ['D02.241.081.069.366.350', 'D02.626.290.350', 'D05.750.259.341', 'D25.720.259.341', 'D25.919.367.341', 'J01.637.051.720.259.341', 'J01.637.051.919.367.341'], ['A0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
Moderate alcohol consumption during pregnancy and child development. | On the basis of prospectively collected data from 7,525 pregnancies it was examined whether moderate but daily alcohol consumption during pregnancy has consequences for child development during the first 3 years. The women were taken into the study during the first trimester of pregnancy and were seen every 4 weeks. So... | ['Age Factors', 'Alcohol Drinking', 'Child, Preschool', 'Female', 'Fetal Alcohol Spectrum Disorders', 'Fetus', 'Growth', 'Humans', 'Infant', 'Infant, Newborn', 'Pregnancy'] | 7,389,736 | [['N05.715.350.075', 'N06.850.490.250'], ['F01.145.317.269'], ['M01.060.406.448'], ['C13.703.277.220', 'C16.300.070', 'C25.775.100.087.323'], ['A16.378'], ['G07.345.249'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['M01.060.703.520'], ['G08.686.784.769']] | ['Health Care [N]', 'Psychiatry and Psychology [F]', 'Named Groups [M]', 'Diseases [C]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Lack of DNase I mRNA sequences in murine lenses. | Clarity of the mammalian lens is due in part to the complete lack of internal organelles, including nuclei, within the lens fiber cells that compose the bulk of the lens. Experimental evidence shows that as the differentiation of lens fiber cells progresses, nuclei and nuclear DNA are actively degraded. Prior character... | ['Animals', 'Blotting, Northern', 'DNA Fragmentation', 'Deoxyribonuclease I', 'Lens, Crystalline', 'Mice', 'Polymerase Chain Reaction', 'RNA, Messenger'] | 9,238,085 | [['B01.050'], ['E05.196.401.095', 'E05.301.300.074', 'E05.601.100'], ['G05.200.230'], ['D08.811.277.352.335.350.250'], ['A09.371.060.500'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.393.620.500'], ['D13.444.735.544']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A steered response power iterative method for high-accuracy acoustic source localization. | Source localization using the steered response power (SRP) usually requires a costly grid-search procedure. To address this issue, a modified SRP algorithm was recently introduced, providing improved robustness when using coarser spatial grids. In this letter, an iterative method based on the modified SRP is presented.... | ['Acoustics', 'Algorithms', 'Motion', 'Numerical Analysis, Computer-Assisted', 'Signal Processing, Computer-Assisted', 'Signal-To-Noise Ratio', 'Sound', 'Sound Spectrography', 'Time Factors', 'Transducers'] | 24,116,399 | [['H01.671.031'], ['G17.035', 'L01.224.050'], ['G01.482'], ['L01.224.680.700'], ['L01.224.800'], ['E05.318.370.800.875', 'E05.318.740.872.875', 'G17.800.500', 'N05.715.360.325.700.840', 'N05.715.360.750.725.750', 'N06.850.520.445.800.875', 'N06.850.520.830.872.750'], ['G01.750.770.776'], ['E05.855'], ['G01.910.857'], [... | ['Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Antipyretic and anti-nociceptive effects of methanol extract of leaves of Fimbristylis miliacea in mice model. | ETHNOPHARMACOLOGICAL RELEVANCE: Fimbristylis miliacea (L.) Vahl (Cyperaceae) is a grass like herb usually grows as a weed in rice fields and is mainly distributed in tropical or sub-tropical countries of south and south-east Asia, central America, northern Australia and west Africa. The plant has been traditionally use... | ['Acetic Acid', 'Analgesics', 'Animals', 'Antipyretics', 'Cyperaceae', 'Disease Models, Animal', 'Female', 'Fever', 'Formaldehyde', 'Male', 'Methanol', 'Mice', 'Pain', 'Plant Extracts', 'Plant Leaves', 'Saccharomyces cerevisiae', 'Solvents'] | 31,306,693 | [['D02.241.081.018.165', 'D10.251.400.045.500'], ['D27.505.696.663.850.014', 'D27.505.954.427.040'], ['B01.050'], ['D27.505.696.068'], ['B01.650.940.800.575.912.250.312'], ['C22.232', 'E05.598.500', 'E05.599.395.080'], ['C23.888.119.344'], ['D02.047.407'], ['D02.033.623'], ['B01.050.150.900.649.313.992.635.505.500'], [... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Responsiveness of rat aorta and pulmonary artery to cGMP generators in the presence of thiol or heme oxidant. | This study investigated the effects of thiol and heme oxidants on responsiveness to cGMP generators in isolated rat aorta and pulmonary artery using an organ chamber. The nitric oxide (NO) donor sodium nitroprusside (SNP)-induced relaxation was impaired by exposure to the thiol oxidant diamide in both the aorta and the... | ['Animals', 'Aorta', 'Benzoates', 'Biphenyl Compounds', 'Cyclic GMP', 'Diamide', 'Dithiothreitol', 'Hydrocarbons, Fluorinated', 'In Vitro Techniques', 'Male', 'Nitric Oxide Donors', 'Nitroprusside', 'Oxidants', 'Oxidative Stress', 'Pulmonary Artery', 'Pyrazoles', 'Pyridines', 'Rats, Wistar', 'Soluble Guanylyl Cyclase',... | 31,036,520 | [['B01.050'], ['A07.015.114.056'], ['D02.241.223.100', 'D02.455.426.559.389.127'], ['D02.455.426.559.389.185'], ['D03.633.100.759.646.454.160', 'D13.695.462.275', 'D13.695.667.454.160', 'D13.695.827.426.160'], ['D02.172.300'], ['D02.033.800.196', 'D02.886.740.224', 'D09.853.196'], ['D02.455.526.510'], ['E05.481'], ['D2... | ['Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Identifying the interactions between natural, non-caloric sweeteners and the human sweet receptor by molecular docking. | Natural sweeteners, such as stevia and thaumatin, exert their sweet taste by specifically binding to sweet taste receptors. However, the molecular basis of their sweetening power remains to be ascertained. In the present study, we built a comparative model of the hT1R2 and hT1R3 subunits in order to characterize their ... | ['Humans', 'Molecular Docking Simulation', 'Plant Proteins', 'Receptors, G-Protein-Coupled', 'Stevia', 'Sweetening Agents'] | 29,853,362 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.595.249', 'L01.224.160.249'], ['D12.776.765'], ['D12.776.543.750.695'], ['B01.650.940.800.575.912.250.100.843'], ['D27.720.372.300.353.609', 'G07.203.300.514.500.400.700', 'J02.500.514.500.400.700']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Measurement of free testosterone in normal women and women with androgen deficiency: comparison of methods. | Androgen deficiency in women is increasingly recognized as a new clinical syndrome and has raised our awareness of the importance of accurate and well-validated measurements of serum free testosterone (T) concentrations in women. Therefore, we compared serum free T levels measured by equilibrium dialysis to those measu... | ['Adult', 'Androgens', 'Case-Control Studies', 'Dialysis', 'Female', 'Humans', 'Middle Aged', 'Radioimmunoassay', 'Reproducibility of Results', 'Sensitivity and Specificity', 'Sex Hormone-Binding Globulin', 'Testosterone'] | 14,764,757 | [['M01.060.116'], ['D27.505.696.399.472.161'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['E05.196.353', 'G02.186'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E01.370.384.700', 'E05.478.566.639', 'E05.601.470.639'], ['E05.318.370.725', 'E05.337.851', 'N... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Automation of a clean-up procedure for determination of trichothecenes in cereals using a charcoal-alumina column. | Automation of the clean-up procedure for trichothecenes on a charcoal-alumina column is described. Standard high-performance liquid chromatographic equipment was used for the clean-up step. An acetonitrile-water (84 + 16, v/v) extract of the sample was cleaned up on a column packed with charcoal-alumina-Celite, which w... | ['Aluminum Oxide', 'Charcoal', 'Chromatography, Gas', 'Chromatography, High Pressure Liquid', 'Edible Grain', 'Food Contamination', 'Trichothecenes'] | 1,644,886 | [['D01.056.050', 'D01.650.550.050'], ['D01.268.150.150'], ['E05.196.181.349'], ['E05.196.181.400.300'], ['A18.024.500.750.500', 'B01.650.160.250', 'B01.650.510.250', 'G07.203.300.300.550', 'G07.203.300.775.500', 'J02.500.300.550', 'J02.500.775.500'], ['J01.576.423.850.730.500.249', 'N06.850.460.400', 'N06.850.601.500.2... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
For Debate: The Two Paths of Growth Hormone (Excess and Deficiency): Both Roads Uniquely Lead to Diabetes Mellitus. | Glucose dysregulation (GD), a feature of growth hormone excess, in the setting of acromegaly is well known by clinicians. However, less well known is that GD may be a feature of growth hormone deficiency. The fact that either ends of the spectrum of growth hormone (excess or deficiency) can be associated with diabetes ... | ['Acromegaly', 'Diabetes Mellitus', 'Glucose', 'Human Growth Hormone', 'Humans'] | 32,780,951 | [['C05.116.132.082', 'C10.228.140.617.738.250.100', 'C19.700.355.179'], ['C18.452.394.750', 'C19.246'], ['D09.947.875.359.448'], ['D06.472.699.631.525.425.875', 'D12.644.548.691.525.425.875'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Protocol for work place adjusted intelligent physical exercise reducing musculoskeletal pain in shoulder and neck (VIMS): a cluster randomized controlled trial. | BACKGROUND: Neck and shoulder complaints are common among employees in sedentary occupations characterized by intensive computer use. Specific strength training is a promising type of physical exercise for relieving neck and shoulder pain in office workers. However, the optimal combination of frequency and exercise dur... | ['Adult', 'Clinical Protocols', 'Cluster Analysis', 'Denmark', 'Exercise Therapy', 'Female', 'Humans', 'Male', 'Middle Aged', 'Neck Pain', 'Occupational Diseases', 'Outcome Assessment, Health Care', 'Physical Fitness', 'Resistance Training', 'Sedentary Behavior', 'Shoulder Pain', 'Teaching', 'User-Computer Interface', ... | 20,687,940 | [['M01.060.116'], ['E02.183', 'N05.715.360.330.125'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['Z01.542.816.124'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.888.592.612.553'], ['C24'], ['H01.770.6... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Psychiatry and Psycholo... | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 1 | 1 |
Regulated expression of the IL-31 receptor in bronchial and alveolar epithelial cells, pulmonary fibroblasts, and pulmonary macrophages. | Interleukin-31 (IL-31), an IL-6 cytokine family member, is proposed to play a role in animal models of airway hyperreactivity. It is produced by activated T cells and signals via a heterodimeric receptor complex composed of IL-31Ralpha and OSMRbeta. Only low levels of IL-31Ralpha expression have been demonstrated in pu... | ['Bronchi', 'Cell Proliferation', 'Cells, Cultured', 'Culture Media, Conditioned', 'DNA', 'Dexamethasone', 'Epithelial Cells', 'Fibroblasts', 'Gene Expression Regulation', 'Humans', 'Immunoblotting', 'Macrophages, Alveolar', 'Pulmonary Alveoli', 'RNA, Messenger', 'Receptors, Interleukin', 'Reverse Transcriptase Polymer... | 18,439,099 | [['A04.411.125'], ['G04.161.750', 'G07.345.249.410.750'], ['A11.251'], ['D27.720.470.305.250', 'E07.206.250'], ['D13.444.308'], ['D04.210.500.745.432.769.344', 'D04.210.500.908.238'], ['A11.436'], ['A11.329.228'], ['G05.308'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.320', 'E05.601.470.320'], ['A1... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Tissue ablation accelerated by peripheral scanning mode with high-intensity focused ultrasound: a study on isolated porcine liver perfusion. | The aims of this study were to investigate the feasibility of accelerated tissue ablation using a peripheral scanning mode with high-intensity focused ultrasound (HIFU) and to explore the effect of flow rate on total energy consumption of the target tissues. Using a model of isolated porcine liver perfusion via the por... | ['Animals', 'Feasibility Studies', 'Hepatectomy', 'High-Intensity Focused Ultrasound Ablation', 'In Vitro Techniques', 'Liver', 'Perfusion', 'Swine', 'Ultrasonography'] | 23,711,500 | [['B01.050'], ['E05.318.372.550', 'E05.337.675', 'N05.715.360.330.550', 'N06.850.520.450.550'], ['E04.210.556'], ['E02.565.280.945.399', 'E04.014.380'], ['E05.481'], ['A03.620'], ['E05.680'], ['B01.050.150.900.649.313.500.880'], ['E01.370.350.850']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Economic impact of malignant mesothelioma in Italy: an estimate of the public and social costs. | BACKGROUND: Despite their considerable interest for public health policies and for occupational disease management and assessment, the economic costs of asbestos-related diseases (ARDs) for society have not been fully estimated or even frequently discussed.OBJECTIVES: The aim of this study was to estimate the economic ... | ['Aged', 'Aged, 80 and over', 'Cost of Illness', 'Female', 'Health Care Costs', 'Humans', 'Italy', 'Lung Neoplasms', 'Male', 'Mesothelioma', 'Mesothelioma, Malignant', 'Middle Aged', 'Occupational Diseases', 'Public Health'] | 29,086,761 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['N03.219.151.165', 'N05.715.360.300.800.438.375.182', 'N06.850.520.308.980.438.475.046'], ['N03.219.151.400', 'N05.300.375'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['C04.557.470.035.510', '... | ['Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
Symptoms mimicking dementia in a 60-year-old woman with bipolar disorder: a case report. | BACKGROUND: Dementia is generally considered an irreversible process of cognitive decline that can be caused by different neurodegenerative diseases. However, in some cases, dementia is caused by a non-neurodegenerative disease, such as an affective disorder. In these cases, the dementia can be reversible. Nevertheless... | ['Bipolar Disorder', 'Cognition Disorders', 'Dementia', 'Depressive Disorder, Major', 'Diagnosis, Differential', 'Female', 'Humans', 'Middle Aged'] | 24,951,023 | [['F03.084.500'], ['F03.615.250'], ['C10.228.140.380', 'F03.615.400'], ['F03.600.300.375'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Psychiatry and Psychology [F]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Aza-peptides. II. X-ray structures of aza-alanine and aza-asparagine-containing peptides. | In order to determine the structural consequences of the N alpha/C alpha H exchange in aza-peptides, we have solved the crystal molecular structures of some derivatives containing the aza-analogue of asparagine [Z-AzAsn(Me)-NMe2 (1), Z-AzAsn(Me)-Pro-NHiPr (2) and Piv-Pro-AzAsn(Me)-NHiPr (5)], aspartic acid [Z-AzAsp(OEt... | ['Alanine', 'Asparagine', 'Crystallography, X-Ray', 'Hydrogen Bonding', 'Peptides', 'Protein Conformation', 'Stereoisomerism'] | 9,266,483 | [['D12.125.042'], ['D12.125.068.060', 'D12.125.095.165', 'D12.125.154.049'], ['E05.196.309.742.225'], ['G02.282'], ['D12.644'], ['G02.111.570.820.709'], ['G02.607.445.682']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Early life stress delays hippocampal development and diminishes the adult stem cell pool in mice. | Early life stress predisposes to mental illness and behavioral dysfunction in adulthood, but the mechanisms underlying these persistent effects are poorly understood. Stress throughout life impairs the structure and function of the hippocampus, a brain system undergoing considerable development in early life. The long-... | ['Animals', 'Cell Proliferation', 'Dentate Gyrus', 'Female', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Neural Stem Cells', 'Neurogenesis', 'Stress, Psychological'] | 30,858,462 | [['B01.050'], ['G04.161.750', 'G07.345.249.410.750'], ['A08.186.211.180.405.200', 'A08.186.211.200.885.287.500.345.200'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['A11.872.653'], ['G04.152.912', 'G07.345.500.325.377.687', 'G08.686.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Neurons in the supplementary eye field of rhesus monkeys code visual targets and saccadic eye movements in an oculocentric coordinate system. | 1. We investigated whether neurons in the supplementary eye field (SEF) of macaque monkeys code saccadic eye movements in oculocentric coordinates (relative to the current direction of fixation) or in craniocentric coordinates (relative to the head). Craniocentric coding in SEF had been previously suggested by the conv... | ['Animals', 'Brain Mapping', 'Fixation, Ocular', 'Frontal Lobe', 'Macaca mulatta', 'Male', 'Neurons', 'Photic Stimulation', 'Saccades', 'Visual Perception'] | 8,871,203 | [['B01.050'], ['E01.370.350.578.875.500', 'E01.370.376.537.625.500', 'E05.629.875.500'], ['G14.350.253'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['A08.675', 'A11.671'], ['E05.723.729'], ['G14.350.500'], ['F02.463.593.932']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Graded changes in enamel component volumes resulted from a short tooth bleaching procedure. | AIM: To test the hypothesis that changes in enamel component volumes (mineral, organic, and water volumes, and permeability) are graded from outer to inner enamel after a short bleaching procedure.MATERIALS AND METHODS: Extracted unerupted human third molars had half of their crowns bleached (single bleaching session, ... | ['Dental Enamel', 'Hardness', 'Humans', 'Hydrogen Peroxide', 'Microscopy, Electron, Scanning', 'Microscopy, Polarization', 'Minerals', 'Molar, Third', 'Spectrophotometry', 'Surface Properties', 'Tooth Bleaching', 'Tooth Bleaching Agents', 'Tooth Demineralization', 'Tooth Permeability'] | 26,852,001 | [['A14.549.167.900.255'], ['G01.374.647'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['E01.370.350.515.624', 'E05.595.624'], ['D01.578'], ['A14.549.167.860.525.500'], ... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Changes in breast cancer transcriptional profiles after treatment with the aromatase inhibitor, letrozole. | OBJECTIVE: The aim of the study was to identify changes in tumour expression profiling associated with short-term therapy of breast cancer patients with letrozole.EXPERIMENTAL DESIGN: Microarray analysis was performed on RNA extracted from paired tumour core biopsies taken before and after 14 days of treatment with let... | ['Aromatase Inhibitors', 'Breast Neoplasms', 'Cluster Analysis', 'Databases, Nucleic Acid', 'Female', 'Gene Expression Regulation, Neoplastic', 'Genes, Neoplasm', 'Humans', 'Letrozole', 'Nitriles', 'Oligonucleotide Array Sequence Analysis', 'Polymerase Chain Reaction', 'Transcription, Genetic', 'Triazoles'] | 17,885,619 | [['D27.505.519.389.870.300', 'D27.505.696.399.450.327.149', 'D27.505.696.399.450.855.300'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.740.250', 'N05.715.360.750.200', 'N06.850.520.830.250'], ['L01.313.500.750.300.188.400.300.500', 'L01.313.500.750.300.188.400.325.630', 'L01.470.750.750.300.500', 'L01.470.750.750.32... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Information Science [L]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Anti-inflammatory activity of fenugreek (Trigonella foenum-graecum | OBJECTIVES: The aim of the present work was to study the anti-inflammatory and anti-arthritic activities of petroleum ether extract of fenugreek seeds.MATERIALS AND METHODS: Fenugreek seed powder was extracted in petroleum ether by cold maceration. This fenugreek seed petroleum ether extract (FSPEE) was analyzed by gas... | ['Alkanes', 'Animals', 'Anti-Inflammatory Agents', 'Arthritis, Experimental', 'Chromatography, Gas', 'Edema', 'Female', 'Granuloma, Foreign-Body', 'Liver', 'Male', 'Plant Extracts', 'Rats, Wistar', 'Seeds', 'Trigonella'] | 27,756,958 | [['D02.455.326.146'], ['B01.050'], ['D27.505.954.158'], ['C05.550.114.015', 'E05.598.500.249'], ['E05.196.181.349'], ['C23.888.277'], ['C23.550.382.437', 'C26.392.560.325'], ['A03.620'], ['D20.215.784.500', 'D26.667'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['A18.024.500.750', 'G07.203.300.775', 'J02.500.775'... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Ciliary body melanoma with optic nerve invasion. | A case of melanoma of the ciliary body is presented. Initially the patient was diagnosed and treated for uveitis, but following CT scanning and ultrasound a tumour was detected and the eye enucleated. Histopathologically it was found that the tumour had invaded the optic nerve head, apparently via Cloquet's canal. | ['Adult', 'Ciliary Body', 'Diagnosis, Differential', 'Humans', 'Male', 'Melanoma', 'Neoplasm Invasiveness', 'Optic Nerve', 'Tomography, X-Ray Computed', 'Uveal Neoplasms', 'Uveitis, Anterior'] | 2,310,725 | [['M01.060.116'], ['A09.371.060.160', 'A09.371.894.280'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.465.625.650.510', 'C04.557.580.625.650.510', 'C04.557.665.510'], ['C04.697.645', 'C23.550.727.645'], ['A08.800.800.120.680'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Regulating Child Sex Robots: Restriction or Experimentation? | In July 2014, the roboticist Ronald Arkin suggested that child sex robots could be used to treat those with paedophilic predilections in the same way that methadone is used to treat heroin addicts. Taking this onboard, it would seem that there is reason to experiment with the regulation of this technology. But most peo... | ['Adult', 'Child', 'Child Abuse, Sexual', 'Commerce', 'Ethical Analysis', 'Government Regulation', 'Humans', 'Morals', 'Pedophilia', 'Play and Playthings', 'Robotics'] | 30,938,445 | [['M01.060.116'], ['M01.060.406'], ['I01.198.240.748.300', 'I01.198.240.856.350.250.255', 'I01.880.735.900.350.250.255'], ['J01.219'], ['K01.752.566.479.113', 'N05.350.244'], ['I01.880.604.394', 'N03.706.358'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.829.500', 'K01.752.566'], ['F03.657.600'], ['I03.450.6... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Technology, Industry, and Agriculture [J]', 'Humanities [K]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
Overexpression of a chloroplast-localized small heat shock protein OsHSP26 confers enhanced tolerance against oxidative and heat stresses in tall fescue. | Small heat shock proteins are involved in stress tolerance. We previously isolated and characterized a rice cDNA clone, Oshsp26, encoding a chloroplast-localized small heat shock protein that is expressed following oxidative or heat stress. In this study, we transferred this gene to tall fescue plants by an Agrobacteri... | ['Chloroplasts', 'Festuca', 'Gene Expression', 'Heat-Shock Proteins, Small', 'Hot Temperature', 'Oryza', 'Oxidative Stress', 'Photosynthesis', 'Photosystem II Protein Complex', 'Plants, Genetically Modified', 'Stress, Physiological'] | 21,984,008 | [['A11.284.430.214.190.875.700.140'], ['B01.650.940.800.575.912.250.822.427'], ['G05.297'], ['D12.776.580.216.270'], ['G01.906.595.543', 'G16.500.275.063.725.710.380', 'G16.500.750.775.710.380', 'N06.230.300.100.725.232', 'N06.230.300.100.725.710.380'], ['B01.650.940.800.575.912.250.822.616'], ['G03.673', 'G07.775.750'... | ['Anatomy [A]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Fluorescent derivatives of AC-42 to probe bitopic orthosteric/allosteric binding mechanisms on muscarinic M1 receptors. | Two fluorescent derivatives of the M1 muscarinic selective agonist AC-42 were synthesized by coupling the lissamine rhodamine B fluorophore (in ortho and para positions) to AC42-NH(2). This precursor, prepared according to an original seven-step procedure, was included in the study together with the LRB fluorophore (al... | ['Allosteric Regulation', 'Calcium', 'Fluorescence Resonance Energy Transfer', 'Fluorescent Dyes', 'Green Fluorescent Proteins', 'HEK293 Cells', 'Humans', 'Models, Molecular', 'Molecular Probes', 'Piperidines', 'Radioligand Assay', 'Receptor, Muscarinic M1', 'Recombinant Fusion Proteins', 'Rhodamines', 'Solubility', 'S... | 22,329,602 | [['G02.111.044'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['E05.196.712.516.600.676.500', 'G01.154.240.280', 'G02.111.255.280'], ['D27.720.233.348', 'D27.720.470.410.505.500'], ['D12.776.532.265'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.599.595'], [... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Serum C-reactive protein in dairy herds. | The purpose of this study was to determine the relationship between the serum level of C-reactive protein (CRP) and lactation and health status. Blood samples were collected every 2 wk for 12 mo from 29 randomly selected dairy cattle on 3 farms. At the time the blood samples were collected, the stage of pregnancy, lact... | ['Animal Welfare', 'Animals', 'Biomarkers', 'Blotting, Western', 'Body Constitution', 'C-Reactive Protein', 'Cattle', 'Cattle Diseases', 'Electrophoresis, Polyacrylamide Gel', 'Female', 'Health Status', 'Lactation', 'Longitudinal Studies', 'Pregnancy', 'Seasons'] | 12,760,474 | [['I01.880.604.100'], ['B01.050'], ['D23.101'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['E01.370.600.115', 'G07.100'], ['D12.776.034.145', 'D12.776.124.050.120', 'D12.776.124.486.157'], ['B01.050.150.900.649.313.500.380.271'], ['C22.196'], ['E05.196.401.402'... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Social and nonsocial content differentially modulates visual attention and autonomic arousal in Rhesus macaques. | The sophisticated analysis of gestures and vocalizations, including assessment of their emotional valence, helps group-living primates efficiently navigate their social environment. Deficits in social information processing and emotion regulation are important components of many human psychiatric illnesses, such as aut... | ['Animals', 'Attention', 'Autonomic Nervous System', 'Macaca mulatta', 'Male', 'Photic Stimulation', 'Social Environment'] | 22,046,313 | [['B01.050'], ['F02.830.104.214'], ['A08.800.050'], ['B01.050.150.900.649.313.988.400.112.199.120.510.550'], ['E05.723.729'], ['I01.880.853.500']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 1 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Psoriasin has divergent effects on the innate immune responses of murine glial cells. | Antimicrobial peptides are an important part of the innate immune defense in the central nervous system (CNS). The expression of the antimicrobial peptides psoriasin (S100A7) is up-regulated during bacterial meningitis. However, the exact mechanisms induced by psoriasin to modulate glial cell activity are not yet fully... | ['Animals', 'Animals, Newborn', 'Cells, Cultured', 'Female', 'HEK293 Cells', 'Humans', 'Immunity, Innate', 'Inflammation Mediators', 'Male', 'Mice', 'Mice, Inbred C57BL', 'Neuroglia', 'S100 Calcium Binding Protein A7', 'S100 Proteins'] | 28,112,393 | [['B01.050'], ['B01.050.050.282'], ['A11.251'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G12.450.564'], ['D23.469'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.420', 'B01.050.150.900.649.313.992.635.505.500.400.420'], ['A08.637', 'A11.650'], ... | ['Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hour-to-hour variability of oxygen saturation in sleep apnea. | STUDY OBJECTIVES: Methods used to express the severity of oxygen desaturation during polysomnography include the average oxygen saturation (AO2), lowest oxygen saturation (LO2), and the percent of the total time with oxygen saturation level lower than 90% (T<90%). We wanted to determine which one of these methods is le... | ['Female', 'Humans', 'Male', 'Middle Aged', 'Oxygen', 'Polysomnography', 'Prospective Studies', 'Sleep Apnea Syndromes'] | 9,515,849 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['D01.268.185.550', 'D01.362.670'], ['E01.370.520.625'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['C08.618.085.852', 'C10.886.425.800.750']] | ['Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
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