Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Expression of a developmentally regulated epitope on fibronectins from the synovial fluid of patients with rheumatic disease. | OBJECTIVE: To determine if differential glycosylation of fibronectin (Fn) in inflammatory synovial fluid (SF) included expression of an oncofetal epitope (Onf Fn) heretofore detected only on Fn derived from embryonal or neoplastic tissue.METHODS: Fn were purified from plasma, SF and synoviocyte conditioned medium by af... | ['Antibodies, Monoclonal', 'Antigens, Neoplasm', 'Autoradiography', 'Blotting, Western', 'Cells, Cultured', 'Chromatography, Affinity', 'Chymotrypsin', 'Culture Media, Conditioned', 'Densitometry', 'Electrophoresis, Polyacrylamide Gel', 'Epitopes', 'Fibronectins', 'Glycosylation', 'Humans', 'Osteoarthritis', 'Rheumatic... | 7,530,772 | [['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D23.050.285'], ['E01.370.225.750.132', 'E05.200.750.132', 'E05.799.256'], ['E05.196.401.143', 'E05.301.300.096', 'E05.478.566.320.200', 'E05.601.262', 'E05.601.470.320.200'], ['A11.251'], ['E05.196.181.400.170'], ['D08.811... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Effects of norgestimate (0.250 mg) in combination with ethinyl estradiol (0.035 mg) on cervical mucus. | The antifertility effect of norgestimate (Ng), 0.250 mg, in combination with ethinyl estradiol (EE), 0.035 mg, on cervical mucus was investigated. The study was conducted over two consecutive cycles: a control cycle followed by a study cycle during which medication was given. Basal body temperature, cervical mucus and ... | ['Adolescent', 'Adult', 'Cervix Mucus', 'Contraceptives, Oral, Combined', 'Ethinyl Estradiol', 'Female', 'Humans', 'Norgestrel'] | 3,776,738 | [['M01.060.057'], ['M01.060.116'], ['A12.200.503.339'], ['D26.310.360', 'D27.505.696.875.360.276.210.100', 'D27.505.954.705.360.276.210.100'], ['D04.210.500.668.651.568.291', 'D06.472.334.851.437.968.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.668.651.693.762']] | ['Named Groups [M]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Marriage is not a safe place: heterosexual marriage and HIV-related vulnerability in Indonesia. | This paper examines the link between heterosexual marriage and women's vulnerability to HIV in Indonesia. In this country, gender relations are currently dominated by traditional beliefs and practices and by religious morality. Data for the current study were collected by means of documentary analysis and archival rese... | ['Cultural Characteristics', 'Female', 'HIV Infections', 'Heterosexuality', 'Humans', 'Indonesia', 'Interpersonal Relations', 'Male', 'Marriage', 'Personal Autonomy', 'Risk Factors', 'Social Environment', 'Vulnerable Populations', "Women's Health", "Women's Rights"] | 18,038,283 | [['I01.076.201.450.324', 'I01.880.853.100.329'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['F01.145.802.975.400', 'G08.686.867.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.145.380', 'Z01.639.580'], ['F01.829.401'], [... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Geographicals [Z]', 'Health Care [N]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Meeting patients' education and decision-making needs for first trimester prenatal aneuploidy screening. | OBJECTIVE: First trimester aneuploidy screening introduces unique challenges to patient education and informed decision-making. Our study assessed the decision-making process among those pregnant patients presenting for this new form of aneuploidy screening.METHOD: A survey instrument was used to assess components of d... | ['Abortion, Legal', 'Adult', 'Aneuploidy', 'Cross-Sectional Studies', 'Decision Making', 'Down Syndrome', 'Female', 'Genetic Testing', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Middle Aged', 'Patient Education as Topic', 'Pregnancy', 'Pregnancy Trimester, First', 'Prenatal Diagnosis', 'Risk', 'Surveys and Que... | 22,024,939 | [['E04.520.050.055'], ['M01.060.116'], ['C23.550.210.050', 'G05.365.590.175.050', 'G05.700.131'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F02.463.785.373'], ['C10.597.606.360.220', 'C16.131.077.327', 'C16.131.260.260', 'C16.320.180.260'], ['E01.370.225.562', 'E05.200.562', 'E05.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
[In honor of the centennial anniversary of the discovery of X-rays by Wilhelm Conrad Roentgen]. | The subject of this report is the life of W. C. Roentgen, the history of the discovery of X-rays and their role in contemporary science. Roentgen's life was entirely filled with creative scientific work. The centennial year of the discovery of X-ray, 1995, will be an opportunity for radiologists and other members of th... | ['Germany', 'History, 19th Century', 'Nobel Prize', 'Physics', 'Radiology', 'X-Rays'] | 9,304,378 | [['Z01.542.315'], ['K01.400.504.937'], ['K01.150.567'], ['H01.671'], ['H02.403.740'], ['G01.358.500.505.970', 'G01.750.250.970', 'G01.750.750.918']] | ['Geographicals [Z]', 'Humanities [K]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
[A triple operation of perforating corneal transplantation, cataract extraction and implantation of an intraocular lens]. | The triple operation was performed in 7 patients (4 men and 3 women). The age of the patients was 18-56 years, the period of hospitalization 3 to 5 days. The surgery was performed in a light intravenous anaesthesia (NLA) or topical anaesthesia. The diameter of the graft oscillated between 7.25 and 9.0 mm. In all the ca... | ['Adult', 'Cataract Extraction', 'Corneal Transplantation', 'Female', 'Follow-Up Studies', 'Humans', 'Lenses, Intraocular', 'Male', 'Middle Aged', 'Treatment Outcome', 'Visual Acuity'] | 1,341,310 | [['M01.060.116'], ['E04.540.825.249'], ['E02.095.147.725.225', 'E04.540.825.374', 'E04.936.580.225'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.632.500.460', 'E07.695.460'], ['M01.060.116.630'], ['E01.789.800', 'N04.... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Prevalence and factors associated with social avoidance of recovered SARS patients in the Hong Kong general population. | The study investigated the general population's perceived infectivity of asymptomatic and recovered severe acute respiratory syndrome (SARS) patients and factors associated with avoidance and discriminatory attitudes, including demographic background, SARS-related perceptions and emotional response to the SARS epidemic... | ['Adolescent', 'Adult', 'Demography', 'Female', 'Health Knowledge, Attitudes, Practice', 'Hong Kong', 'Humans', 'Male', 'Middle Aged', 'Prejudice', 'Prevalence', 'Risk Factors', 'Severe Acute Respiratory Syndrome', 'Social Isolation'] | 16,880,214 | [['M01.060.057'], ['M01.060.116'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['F01.100.150.500', 'N05.300.150.410'], ['Z01.252.474.164.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['F01.145.813.550', 'F01.829.595'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Polymorphisms in ACE and ACTN3 Genes and Blood Pressure Response to Acute Exercise in Elite Male Athletes from Serbia. | Physiological adaptations to various types of prolonged and intensive physical activity, as seen in elite athletes from different sports, include changes in blood pressure (BP) response to acute exercise. Also, functional polymorphisms of the angiotensin I converting enzyme (ACE) and alfa-actinin-3 (ACTN3) genes are sh... | ['Actinin', 'Adult', 'Alleles', 'Anthropometry', 'Athletes', 'Blood Pressure', 'Exercise', 'Gene Frequency', 'Humans', 'Male', 'Peptidyl-Dipeptidase A', 'Serbia'] | 29,269,700 | [['D05.750.078.730.248', 'D12.776.210.500.095', 'D12.776.220.525.250'], ['M01.060.116'], ['G05.360.340.024.340.030'], ['E01.370.600.024', 'E05.041', 'N06.850.505.200.100'], ['M01.072'], ['E01.370.600.875.249', 'G09.330.380.076'], ['G11.427.410.698.277', 'I03.350'], ['G05.330'], ['B01.050.150.900.649.313.988.400.112.400... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Twenty-four hour profiles of plasma C-peptide in type 1 (insulin-dependent) diabetic children. | Twenty-four hour profiles of plasma C-peptide, an index of endogenous insulin secretion, were performed in 15 Type 1 (insulin-dependent) diabetic children. Plasma C-peptide was detectable in six children, of whom four ('C-peptide producers') had peak values above normal fasting levels. In each of the six children with ... | ['Adolescent', 'Blood Glucose', 'C-Peptide', 'Child', 'Circadian Rhythm', 'Diabetes Mellitus, Type 1', 'Female', 'Humans', 'Insulin', 'Male', 'Peptides'] | 7,047,271 | [['M01.060.057'], ['D09.947.875.359.448.500'], ['D06.472.699.587.200.500.250', 'D12.644.548.586.200.500.250'], ['M01.060.406'], ['G07.180.562.190'], ['C18.452.394.750.124', 'C19.246.267', 'C20.111.327'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['D... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Hyperinsulinemia and Insulin Resistance in Dopamine â-Hydroxylase Deficiency. | Context: Dopamine â-hydroxylase (DBH) deficiency is a rare genetic disorder characterized by failure to convert dopamine to norepinephrine. DBH-deficient patients lack sympathetic adrenergic function and are therefore predisposed to orthostatic hypotension. DBH-deficient mice exhibit hyperinsulinemia, lower plasma gluc... | ['Adolescent', 'Animals', 'Autonomic Nervous System Diseases', 'Dopamine beta-Hydroxylase', 'Droxidopa', 'Female', 'Humans', 'Hyperinsulinism', 'Insulin', 'Insulin Resistance', 'Mice', 'Norepinephrine', 'Prognosis'] | 27,778,639 | [['M01.060.057'], ['B01.050'], ['C10.177'], ['D08.811.682.690.708.292'], ['D02.092.311.830.220', 'D02.455.426.559.389.657.166.175.830.220', 'D12.125.154.800.875'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.968'], ['D06.472.699.587.200.500.625', 'D12.644.548.586.200.500.625'], ['C18.452.394.968.500'... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Lactobacillus rhamnosus septicemia in a diabetic patient associated with probiotic use: a case report]. | BACKGROUND: probiotic agents are increasingly used as over the counter drugs for the treatment of a variety of inflammatory and infectious conditions. The rationale of their use seems to restore a friendly bacterial flora in the gut. Complications of probiotic use, although rarely reported, can occur.OBSERVATION: we de... | ['Administration, Oral', 'Amoxicillin', 'Diabetes Mellitus, Type 2', 'Female', 'Humans', 'Lactobacillus rhamnosus', 'Middle Aged', 'Probiotics', 'Sepsis', 'Time Factors', 'Treatment Outcome'] | 18,390,430 | [['E02.319.267.100'], ['D02.065.589.099.750.750.050.050', 'D02.886.108.750.750.050.050', 'D03.633.100.300.750.750.050.050'], ['C18.452.394.750.149', 'C19.246.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.353.750.450.475.700', 'B03.510.460.400.410.475.475.700', 'B03.510.550.450.475.700'], ['M01.060.116.6... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 |
The use of gadolinium in the MR imaging of bone tumors. | Before determining the role of gadolinium in the evaluation of the solitary bone tumor, the practicing radiologist needs to determine which solitary bone lesions merit further evaluation with magnetic resonance imaging and why further imaging is required. A practical approach in applying magnetic resonance imaging to t... | ['Antineoplastic Agents', 'Bone Neoplasms', 'Contrast Media', 'Drug Combinations', 'Edema', 'Evaluation Studies as Topic', 'Gadolinium', 'Gadolinium DTPA', 'Humans', 'Image Enhancement', 'Joint Diseases', 'Magnetic Resonance Imaging', 'Meglumine', 'Muscle, Skeletal', 'Muscular Diseases', 'Necrosis', 'Neoplasm Staging',... | 9,285,999 | [['D27.505.954.248'], ['C04.588.149', 'C05.116.231'], ['D27.505.259.500', 'D27.720.259'], ['D26.310'], ['C23.888.277'], ['E05.337', 'N05.715.360.335'], ['D01.268.558.362.484', 'D01.552.550.399.484'], ['D02.092.782.590.401', 'D02.241.081.018.639.400', 'D02.257.141'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E0... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Information Science [L]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
The endothelium but not the syncytiotrophoblast of human placenta expresses caveolae. | The human placenta is a complex specialized structure that mediates the interchange of molecules, ions, and gases between maternal and foetal circulation. We have investigated the distribution and expression of caveolae/caveolin in the placenta. Using immunochemical, immunocytochemical, and ultrastructural methods, we ... | ['Adult', 'Caveolae', 'Endothelium, Vascular', 'Female', 'Fluorescent Antibody Technique, Indirect', 'Humans', 'Immunoblotting', 'Immunohistochemistry', 'Microscopy, Electron', 'Placental Circulation', 'Pregnancy', 'Trophoblasts'] | 12,361,683 | [['M01.060.116'], ['A11.284.149.165.175.160', 'A11.284.149.165.570.160', 'A11.284.430.214.190.875.190.880.180.160'], ['A07.015.700.500', 'A10.272.491.355'], ['E01.370.225.500.607.512.240.310', 'E01.370.225.750.551.512.240.310', 'E05.200.500.607.512.240.310', 'E05.200.750.551.512.240.310', 'E05.478.583.375.310'], ['B01.... | ['Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Calcification in untreated non-Hodgkin's mediastinal lymphoma. | We report a case of calcifications in mediastinal non-Hodgkin's lymphoma. Although calcification may occur in lymphoma after chemotherapy or radiotherapy in areas of fibrous healing and scar formation, it has been reported only rarely in untreated non-Hodgkin's lymphoma. | ['Adult', 'Calcinosis', 'Humans', 'Lymphoma, Non-Hodgkin', 'Male', 'Mediastinal Neoplasms', 'Radiography, Thoracic', 'Tomography, X-Ray Computed'] | 9,496,879 | [['M01.060.116'], ['C18.452.174.130'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.386.480', 'C15.604.515.569.480', 'C20.683.515.761.480'], ['C04.588.894.479', 'C08.846.187.580'], ['E01.370.350.700.730'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.8... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The JWS online simulation database. | Summary: JWS Online is a web-based platform for construction, simulation and exchange of models in standard formats. We have extended the platform with a database for curated simulation experiments that can be accessed directly via a URL, allowing one-click reproduction of published results. Users can modify the simula... | ['Computational Biology', 'Computer Simulation', 'Databases, Factual', 'Models, Biological', 'Reproducibility of Results'] | 28,130,238 | [['H01.158.273.180', 'L01.313.124'], ['L01.224.160'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E05.599.395'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725']] | ['Disciplines and Occupations [H]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 |
Characterization of an ambulatory population with stable coronary artery disease and importance of heart rate: the PULSAR registry. | AIMS: To characterize a population with stable coronary artery disease (CAD) in an outpatient setting and to evaluate the importance of resting heart rate (HR), a recently recognized prognostic risk factor.TYPE OF STUDY: A prospective and observational registry of patients with stable CAD followed mainly by cardiologis... | ['Aged', 'Ambulatory Care', 'Coronary Artery Disease', 'Female', 'Heart Rate', 'Humans', 'Male', 'Prospective Studies', 'Registries'] | 20,734,572 | [['M01.060.116.100'], ['E02.760.106', 'N02.421.585.106'], ['C14.280.647.250.260', 'C14.907.137.126.339', 'C14.907.585.250.260'], ['E01.370.600.875.500', 'G09.330.380.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['E05.3... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Low divergence in rDNA ITS sequences among five species of Fucus (Phaeophyceae) suggests a very recent radiation. | Sequences from the two ribosomal DNA internal transcribed spacers (ITS1 and ITS2) were compared among five species of Fucus. Based on the present taxon sampling, parsimony analysis showed that Fucus serratus is the sister-group of the remaining Fucus species when Ascophyllum nodosum was used as an outgroup. The topolog... | ['Base Sequence', 'Conserved Sequence', 'DNA, Ribosomal', 'France', 'Genetic Variation', 'Models, Genetic', 'Molecular Sequence Data', 'Phaeophyta', 'Phylogeny', 'Sequence Alignment', 'Sequence Homology, Nucleic Acid'] | 9,419,231 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.580'], ['D13.444.308.475'], ['Z01.542.286'], ['G05.365'], ['E05.599.395.397'], ['L01.453.245.667'], ['B01.750.600'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['E05.393.751'], ['G02.111.810.550', 'G05.810.550']] | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Geographicals [Z]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 |
p66 Shc and tyrosine-phosphorylated Shc in primary breast tumors identify patients likely to relapse despite tamoxifen therapy. | INTRODUCTION: Shc adapter proteins are secondary messenger proteins involved in various cellular pathways, including those mediating receptor tyrosine kinase signaling and apoptosis in response to stress. We have previously reported that high levels of tyrosine-phosphorylated Shc (PY-Shc) and low levels of its inhibito... | ['Adaptor Proteins, Signal Transducing', 'Antineoplastic Agents, Hormonal', 'Breast Neoplasms', 'Case-Control Studies', 'Female', 'Humans', 'Neoplasm Recurrence, Local', 'Phosphoproteins', 'Phosphorylation', 'Protein Isoforms', 'Receptors, Estrogen', 'Shc Signaling Adaptor Proteins', 'Src Homology 2 Domain-Containing, ... | 17,196,107 | [['D12.644.360.024', 'D12.776.157.057', 'D12.776.476.024'], ['D27.505.954.248.169'], ['C04.588.180', 'C17.800.090.500'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.697.655', 'C23.550.727.655'], ['D12.776.744'], ['G02.111.665', 'G... | ['Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Clinical and electrophysiologic characteristics of sinoatrial entrance block evaluated by direct sinus node electrography: prevalence, relation to antegrade sinoatrial conduction time, and relevance to sinus node disease. | When AV conduction is normal, the absence of VA conduction is not abnormal. Analogous information about retrograde sinoatrial conduction is not available. Although the premature atrial stimulas (PAS) technique can demonstrate the presence of sinoatrial entrance block (SAEB), both its prevalence and its relationship to ... | ['Adolescent', 'Adult', 'Aged', 'Arrhythmias, Cardiac', 'Dizziness', 'Electrophysiology', 'Female', 'Heart Block', 'Heart Conduction System', 'Humans', 'Male', 'Middle Aged', 'Sick Sinus Syndrome', 'Sinoatrial Block', 'Sinoatrial Node'] | 7,315,700 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['C14.280.067', 'C23.550.073'], ['C23.888.592.763.237'], ['H01.158.344.528', 'H01.158.782.236'], ['C14.280.067.558', 'C14.280.123.500', 'C23.550.073.425'], ['A07.541.409'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C14.280.067.093.249... | ['Named Groups [M]', 'Diseases [C]', 'Disciplines and Occupations [H]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Magnetic resonance imaging of penile paraffinoma: case report. | BACKGROUND: Penile paraffinoma is a well-known delayed complication of paraffin oil injection into the penis for penile girth augmentation but its MRI features have not been previously described.CASE PRESENTATION: A 35-year-old Ukraine man presented with erectile dysfunction, voiding difficulty and an irregular, hard a... | ['Adult', 'Erectile Dysfunction', 'Humans', 'Magnetic Resonance Imaging', 'Male', 'Oils', 'Paraffin', 'Penis'] | 25,487,566 | [['M01.060.116'], ['C12.294.644.486', 'F03.835.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.825.500'], ['D10.627'], ['D02.455.612'], ['A05.360.444.492']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A previously unidentified acepromazine metabolite in humans: implications for the measurement of acepromazine in blood. | High-performance liquid chromatography-diode-array detection results obtained during the investigation of two cases involving acepromazine prompted us to study the stability of the drug in blood. It was found that acepromazine can undergo in vitro conversion by human red blood cells to 2-(1-hydroxyethyl)promazine, a pr... | ['Acepromazine', 'Antipsychotic Agents', 'Chromatography, High Pressure Liquid', 'Drug Combinations', 'Drug Stability', 'Etorphine', 'Forensic Medicine', 'Homicide', 'Humans', 'Methotrimeprazine', 'Promazine', 'Suicide, Attempted'] | 10,488,925 | [['D02.886.369.029', 'D03.633.300.783.029'], ['D27.505.696.277.950.040', 'D27.505.954.427.210.950.040', 'D27.505.954.427.700.872.331'], ['E05.196.181.400.300'], ['D26.310'], ['E05.916.330'], ['D03.132.577.249.270', 'D03.605.497.320', 'D03.633.400.686.320', 'D04.615.723.795.270'], ['H02.403.330', 'I01.198.780.937'], ['I... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Psychiatry and Psychology [F]'] | 0 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
Protein and antigen variability among strains of Mycoplasma arthritidis. | Six strains of Mycoplasma arthritidis isolated from different host tissues were examined for differences in their proteins and antigens by using one- and two-dimensional electrophoretic techniques as well as immunoblotting. One-dimensional electrophoresis revealed differences in concentrations of individual bands, but ... | ['Animals', 'Antigenic Variation', 'Antigens, Bacterial', 'Arthritis, Infectious', 'Bacterial Proteins', 'Electrophoresis, Gel, Two-Dimensional', 'Electrophoresis, Polyacrylamide Gel', 'Humans', 'Immunoblotting', 'Isoelectric Focusing', 'Mycoplasma', 'Rats', 'Rodent Diseases'] | 1,576,410 | [['B01.050'], ['G05.365.073', 'G12.500.249'], ['D23.050.161'], ['C01.100', 'C05.550.114.099'], ['D12.776.097'], ['E05.196.401.250', 'E05.301.300.230'], ['E05.196.401.402', 'E05.301.300.319'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.478.566.320', 'E05.601.470.320'], ['E05.196.401.663', 'E05.301.300.663'],... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Acute abdominal complications in bone marrow transplant recipients]. | Bone marrow transplant is currently the treatment of choice for a number of haematological neoplasms. High doses of antiblastic drugs, immunosuppressive agents and acute graft versus host disease before and after bone marrow transplant cause toxic damage to the liver and to the gastrointestinal tract. Related acute abd... | ['Abdomen, Acute', 'Appendicitis', 'Bone Marrow Transplantation', 'Cholangitis', 'Cholecystitis', 'Colitis', 'Emergencies', 'Graft vs Host Disease', 'Humans', 'Ileitis', 'Pancreatitis', 'Postoperative Complications', 'Prognosis'] | 12,239,761 | [['C23.888.592.612.054.200', 'C23.888.821.030.249'], ['C01.463.099', 'C06.405.205.099', 'C06.405.469.110.207'], ['E02.095.147.725.040', 'E04.936.580.040'], ['C06.130.120.200'], ['C06.130.564.263'], ['C06.405.205.265', 'C06.405.469.158.188'], ['C23.550.291.781', 'N06.230.100.083', 'N06.850.376'], ['C20.452'], ['B01.050.... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Injectable poly(amidoamine)-poly(ethylene glycol)-poly(amidoamine) triblock copolymer hydrogel with dual sensitivities: pH and temperature. | A novel triblock copolymer for use in an injectable pH- and temperature-sensitive hydrogel is synthesized by conjugating poly(amidoamine) (PAA) to poly(ethylene glycol): poly(amidoamine)-poly(ethylene glycol)-poly(amidoamine) (PAA-PEG-PAA). The polymer was characterized with (1)H NMR and gel permeation chromatography i... | ['Animals', 'Biocompatible Materials', 'Hydrogel, Polyethylene Glycol Dimethacrylate', 'Hydrogen-Ion Concentration', 'Injections, Subcutaneous', 'Nylons', 'Polyamines', 'Polyethylene Glycols', 'Polymers', 'Rats', 'Rats, Sprague-Dawley', 'Temperature'] | 19,296,656 | [['B01.050'], ['D25.130', 'D27.720.102.130', 'J01.637.051.130'], ['D02.033.455.250.700.485', 'D05.750.219.500', 'D05.750.741.485', 'D20.280.320.609.500', 'D25.720.532.500', 'D25.720.741.485', 'D26.255.165.320.375.375', 'J01.637.051.720.584.500', 'J01.637.051.720.741.485'], ['G02.300'], ['E02.319.267.530.620'], ['D05.75... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Urethro-cavernous fistula from blunt penile trauma. | An unusual case of traumatic urethro-cavernous fistula from the fall of a heavy object upon the flaccid penis is described. In the absence of clinical evidence of urinary extravasation, prompt performance of corpus cavernosography helped detect the existence of such a fistulous communication. Institution of prompt supr... | ['Accidents, Occupational', 'Adult', 'Humans', 'Male', 'Penile Diseases', 'Penis', 'Radiography', 'Urethra', 'Urinary Fistula', 'Wounds, Nonpenetrating'] | 7,218,388 | [['N06.850.135.240'], ['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.494'], ['A05.360.444.492'], ['E01.370.350.700'], ['A05.360.444.492.726', 'A05.810.876'], ['C12.706.881', 'C13.351.875.881', 'C23.300.575.825'], ['C26.974']] | ['Health Care [N]', 'Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The correlation of student performance in preclinical and clinical prosthodontic assessments. | Tracking student performance in preclinical and clinical courses can be helpful in developing and refining a curriculum. Our objective was to correlate student performance on three fixed prosthodontic examinations taken by eighty junior dental students. Examinations included a knowledge-based objective structured clini... | ['Clinical Competence', 'Competency-Based Education', 'Crowns', 'Dental Abutments', 'Dental Casting Technique', 'Dental Veneers', 'Denture Design', 'Denture, Partial, Fixed', 'Denture, Partial, Temporary', 'Education, Dental', 'Educational Measurement', 'Humans', 'Models, Anatomic', 'Motor Skills', 'Prosthodontics', 'S... | 17,389,571 | [['I02.399.630.210', 'N04.761.210', 'N05.715.175'], ['I02.158.210'], ['E06.780.346.250', 'E07.695.190.088'], ['E06.780.346.500', 'E07.695.190.175'], ['E06.780.250', 'E06.912.115'], ['E06.780.346.750', 'E07.695.190.196'], ['E06.780.346.760.300', 'E06.912.250'], ['E06.780.346.760.943.271', 'E07.695.190.200.220.220'], ['E... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Disciplines and Occupations [H]', 'Named ... | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
Low lumbar burst fractures: a unique fracture mechanism sustained in our current overseas conflicts. | BACKGROUND CONTEXT: The most common location for burst fractures occurs at the thoracolumbar junction, where the stiff thoracic spine meets the more flexible lumbar spine. With our current military conflicts in Iraq and Afghanistan, we have seen a disproportionate number of low lumbar burst fractures.PURPOSE: To report... | ['Adult', 'Afghan Campaign 2001-', 'Female', 'Humans', 'Iraq War, 2003-2011', 'Lumbar Vertebrae', 'Male', 'Neurosurgical Procedures', 'Postoperative Complications', 'Retrospective Studies', 'Spinal Cord Injuries', 'Spinal Fractures', 'Young Adult'] | 21,982,760 | [['M01.060.116'], ['I01.880.735.950.250.094', 'K01.400.504.984.124'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['I01.880.735.950.250.782', 'K01.400.504.984.249'], ['A02.835.232.834.519'], ['E04.525'], ['C23.550.767'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
Association of Chlamydia pneumoniae Infection With Atherosclerotic Plaque Formation. | Atherosclerosis is a complex multifactorial disorder. Studies show that infectious microbial agents may play an important role in the development of atherosclerosis; however, these findings are conflicting. This study investigated the presence of Chlamydia pneumoniae DNA in atherosclerotic plaques of patients suffering... | ['Adult', 'Aged', 'Aged, 80 and over', 'Chlamydia Infections', 'Chlamydophila pneumoniae', 'Cross-Sectional Studies', 'Female', 'Humans', 'Male', 'Middle Aged', 'Plaque, Atherosclerotic', 'Risk Factors'] | 26,573,036 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.150.252.400.210.125', 'C01.150.252.734.301', 'C01.221.812.281.301', 'C01.778.281.301', 'C12.294.668.281.301', 'C13.351.500.711.281.301'], ['B03.440.190.190.230.249'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['B0... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Structure of calmodulin complexed with an olfactory CNG channel fragment and role of the central linker: residual dipolar couplings to evaluate calmodulin binding modes outside the kinase family. | The NMR high-resolution structure of calmodulin complexed with a fragment of the olfactory cyclic-nucleotide gated channel is described. This structure shows features that are unique for this complex, including an active role of the linker connecting the N- and C-lobes of calmodulin upon binding of the peptide. Such li... | ['Amino Acid Motifs', 'Amino Acid Sequence', 'Amino Acids, Acidic', 'Amino Acids, Aromatic', 'Amino Acids, Basic', 'Animals', 'Binding Sites', 'Calmodulin', 'Cyclic Nucleotide-Gated Cation Channels', 'Hydrogen Bonding', 'Hydrophobic and Hydrophilic Interactions', 'Ion Channels', 'Models, Chemical', 'Models, Molecular',... | 15,803,393 | [['G02.111.570.820.709.275.500', 'G02.111.570.820.709.600.500'], ['G02.111.570.060', 'L01.453.245.667.060'], ['D12.125.067'], ['D12.125.072.050'], ['D12.125.068'], ['B01.050'], ['G02.111.570.120'], ['D12.644.360.372.249', 'D12.776.157.125.412.249', 'D12.776.476.387.249'], ['D12.776.157.530.400.337', 'D12.776.543.550.45... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Expression of G1-->S transition regulatory molecules in human urothelial cancer. | Growth of cancer cells is characterized by accelerated passage through the cell cycle, which is often caused by deregulation of the G1-->S transition. In this study the expression of G1-->S transition regulatory molecules was analyzed in 32 transitional cell carcinoma specimens and fifteen normal tissues obtained by cy... | ['Aged', 'Aged, 80 and over', 'CDC2-CDC28 Kinases', 'Carcinoma, Transitional Cell', 'Cyclin D1', 'Cyclin D2', 'Cyclin-Dependent Kinase 2', 'Cyclin-Dependent Kinase 4', 'Cyclin-Dependent Kinases', 'Cyclins', 'Female', 'G1 Phase', 'Humans', 'Male', 'Middle Aged', 'Protein-Serine-Threonine Kinases', 'Proto-Oncogene Protei... | 9,738,978 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['D08.811.913.696.620.682.700.646.500.500', 'D12.644.360.250.067', 'D12.776.167.200.067', 'D12.776.476.250.067'], ['C04.557.470.200.430'], ['D12.644.360.262.150.100', 'D12.776.167.218.150.100', 'D12.776.476.262.150.100', 'D12.776.624.664.700.100'], ['D12.644.360.262.150.20... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Genetic engineering of novel bluer-colored chrysanthemums produced by accumulation of delphinidin-based anthocyanins. | Chrysanthemums (Chrysanthemum morifolium Ramat.) have no purple-, violet- or blue-flowered cultivars because they lack delphinidin-based anthocyanins. This deficiency is due to the absence of the flavonoid 3',5'-hydroxylase gene (F3'5'H), which encodes the key enzyme for delphinidin biosynthesis. In F3'5'H-transformed ... | ["5' Untranslated Regions", 'Alcohol Dehydrogenase', 'Anthocyanins', 'Chrysanthemum', 'Color', 'Cytochrome P-450 Enzyme System', 'Enhancer Elements, Genetic', 'Flowers', 'Genetic Engineering', 'Molecular Structure', 'Pigmentation', 'Plant Proteins', 'Plants, Genetically Modified', 'Promoter Regions, Genetic', 'Reproduc... | 23,926,063 | [['D13.444.735.544.875.885', 'D13.444.735.790.878.885', 'G05.360.340.024.220.880.885', 'G05.360.340.024.340.137.910.885'], ['D08.811.682.047.820.250'], ['D03.383.663.283.266.450.087', 'D03.633.100.150.266.450.087', 'D09.408.084', 'D23.767.124'], ['B01.650.940.800.575.912.250.100.206'], ['G01.590.540.199'], ['D08.244.45... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A loop-to-base processing mechanism underlies the biogenesis of plant microRNAs miR319 and miR159. | The first step in microRNA (miRNA) biogenesis usually involves cleavage at the base of its fold-back precursor. Here, we describe a non-canonical processing mechanism for miRNAs miR319 and miR159 in Arabidopsis thaliana. We found that their biogenesis begins with the cleavage of the loop, instead of the usual cut at th... | ['Arabidopsis', 'Arabidopsis Proteins', 'Base Sequence', 'Bryopsida', 'Conserved Sequence', 'MicroRNAs', 'Molecular Sequence Data', 'Nucleic Acid Conformation', 'RNA Processing, Post-Transcriptional', 'RNA, Plant', 'Sequence Analysis, RNA'] | 19,816,405 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['B01.650.940.800.575.137.500'], ['G02.111.570.580'], ['D13.150.650.319', 'D13.444.735.150.319', 'D13.444.735.790.552.500'], ['L01.453.245.667'], ['G02.111.570.820.486', 'G05.360.580'], ['G02.111.76... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Mechanism of action of aflatoxin B1 in Bacillus megaterium. | Bacillus megaterium cells from various growth phases were equally susceptible to the lethal effects of aflatoxin B1. Known surfactants (EDTA and Tween-80) accentuated the effects of aflatoxin B1. Viability and inulin uptake in aflatoxin B1-exposed cells decreased considerably. The effect was concentration dependent. A ... | ['Aflatoxin B1', 'Aflatoxins', 'Bacillus megaterium', 'Cell Membrane Permeability', 'Dose-Response Relationship, Drug'] | 3,923,926 | [['D03.383.663.283.119.075', 'D03.633.100.150.119.075', 'D23.946.587.142.075'], ['D03.383.663.283.119', 'D03.633.100.150.119', 'D23.946.587.142'], ['B03.300.390.400.158.218.500', 'B03.353.500.100.218.500', 'B03.510.100.100.218.500', 'B03.510.415.400.158.218.500', 'B03.510.460.410.158.218.500'], ['G03.143.335', 'G04.175... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sex hormones mediate interleukin-1 beta production by human osteoblastic HOBIT cells. | The mechanisms by which the sex hormones achieve their bone-sparing effects remains unresolved. Interleukin-1 beta (IL-1 beta) is an autocrine/paracrine regulator of bone that may be produced in an estrogen-sensitive manner. The regulation of IL-1 beta production by the gonadal steroids was tested in the human osteobla... | ['Cell Line', 'Estradiol', 'Flutamide', 'Gonadal Steroid Hormones', 'Humans', 'Interleukin-1', 'Osteoblasts', 'RNA, Messenger', 'Testosterone', 'Tumor Necrosis Factor-alpha'] | 7,649,354 | [['A11.251.210'], ['D04.210.500.365.415.248', 'D06.472.334.851.437.500'], ['D02.065.199.420', 'D02.092.146.113.420'], ['D06.472.334.851'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.010', 'D12.644.276.374.500.400', 'D12.776.467.374.465.010', 'D12.776.467.374.500.400', 'D23.529.374.465.131', ... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A morphometric study of the protective effect of cryotherapy on oral mucositis in cancer patients treated with 5-fluorouracil. | We investigated cytological changes in oral mucosa smears from patients treated with cryotherapy to determine whether cryotherapy prevented mucositis caused by 5-fluorouracil (5-FU) therapy. Patients with gastrointestinal malignancies were divided into four groups; control patients before 5-FU therapy, patients after 5... | ['Adult', 'Aged', 'Antimetabolites, Antineoplastic', 'Cryotherapy', 'Female', 'Fluorouracil', 'Humans', 'Male', 'Middle Aged', 'Mouth Mucosa', 'Neoplasms', 'Stomatitis', 'Treatment Outcome', 'Young Adult'] | 27,644,112 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.519.186.144', 'D27.505.954.248.144', 'D27.888.569.042.030'], ['E02.258'], ['D03.383.742.698.875.404'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['A10.615.550.599', 'A14.549.512'], ['C04'], ['C07.465.864'], ['E01.789.800', 'N04.761.559.590.800... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Synthesis of beta-(1-->4)-oligo-D-mannuronic acid neoglycolipids. | Mammalian Toll-like receptors (TLRs) play important roles in host immune defense. The activation of TLR and down-stream signaling pathways have great impact on human physiology. Chemically diverse microbial products as well as synthetic ligands serve as agonists for these receptors. Recently, synthetic TLR ligands are ... | ['Alginates', 'Glucuronic Acid', 'Glycolipids', 'Hexuronic Acids', 'Humans', 'Ligands', 'Oligosaccharides', 'Toll-Like Receptor 2', 'Toll-Like Receptor 4'] | 18,005,954 | [['D09.698.068'], ['D02.241.081.844.915.162.249', 'D02.241.152.811.162.500', 'D02.241.511.902.915.162.500', 'D09.811.922.162.500'], ['D09.400.410', 'D10.390'], ['D02.241.081.844.915.400', 'D02.241.152.811.400', 'D02.241.511.902.915.400', 'D09.811.922.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.720.470... | ['Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The ghost of public health journalism: past, present, and future. | The news industry is undergoing shrinking newspaper circulations, cuts in science and health coverage, and expansion of Internet news sources. We examine the impact of these changes using a case study set in Libby, Montana. In 1999, a Seattle newspaper story focused attention on asbestos exposure and related diseases i... | ['Asbestos', 'Forecasting', 'History, 20th Century', 'History, 21st Century', 'Humans', 'Journalism, Medical', 'Mining', 'Montana', 'Newspapers as Topic', 'Occupational Exposure', 'Public Health', 'Washington'] | 20,160,563 | [['D01.578.725.050', 'D01.837.725.700.760.070'], ['I01.320'], ['K01.400.504.968'], ['K01.400.504.984'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.737.498.550'], ['J01.576.655.875.500'], ['Z01.107.567.875.560.500'], ['L01.178.682.829.481'], ['N06.850.460.350.600'], ['H02.403.720', 'N01.400.550', 'N06.850'],... | ['Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Humanities [K]', 'Organisms [B]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Geographicals [Z]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 1 |
1. Trigeminal neuralgia. | Trigeminal neuralgia is a common cause of facial pain. It has a significant impact on the quality of life and the socioeconomic functioning of the patient. The aim of this review is to provide recommendations for medical management of trigeminal neuralgia based on current evidence. Based upon the analyses of the litera... | ['Algorithms', 'Analgesics, Non-Narcotic', 'Carbamazepine', 'Catheter Ablation', 'Clinical Protocols', 'Decompression, Surgical', 'Diagnosis, Differential', 'Humans', 'Neurosurgical Procedures', 'Radiosurgery', 'Risk Assessment', 'Trigeminal Ganglion', 'Trigeminal Nerve', 'Trigeminal Neuralgia'] | 19,619,267 | [['G17.035', 'L01.224.050'], ['D27.505.696.663.850.014.040', 'D27.505.954.427.040.100'], ['D03.633.300.240.127'], ['E02.808.750.500', 'E04.014.760.500'], ['E02.183', 'N05.715.360.330.125'], ['E04.188'], ['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.525'], ['E02.815.530', 'E04.525.800.650', 'E05.87... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Tachykinin NK3 and NK1 receptor activation elicits secretion from porcine airway submucosal glands. | 1 We presently characterized the tachykinin receptor subtypes, using tachykinin receptor agonists and selective antagonists, that induce submucosal gland fluid flux (J(G)) from porcine tracheal explants with the hillocks technique. We also investigated the effects of the tachykinin receptor agonists on the electrophysi... | ['Animals', 'Benzamides', 'Dose-Response Relationship, Drug', 'Exocrine Glands', 'Neurokinin-1 Receptor Antagonists', 'Piperidines', 'Receptors, Neurokinin-1', 'Receptors, Neurokinin-3', 'Respiratory Mucosa', 'Swine', 'Trachea'] | 12,522,097 | [['B01.050'], ['D02.065.277', 'D02.241.223.100.100', 'D02.455.426.559.389.127.085'], ['G07.690.773.875', 'G07.690.936.500'], ['A10.336'], ['D27.505.519.625.487', 'D27.505.696.577.487'], ['D03.383.621'], ['D12.776.543.750.695.862.500', 'D12.776.543.750.720.600.830.500', 'D12.776.543.750.750.555.830.500'], ['D12.776.543.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Sulfonate-terminated carbosilane dendron-coated nanotubes: a greener point of view in protein sample preparation. | Reduction or removal of solvents and reagents in protein sample preparation is a requirement. Dendrimers can strongly interact with proteins and have great potential as a greener alternative to conventional methods used in protein sample preparation. This work proposes the use of single-walled carbon nanotubes (SWCNTs)... | ['Anthracenes', 'Chemistry Techniques, Analytical', 'Microscopy, Electron, Scanning', 'Nanotubes', 'Nanotubes, Carbon', 'Proteins', 'Silanes'] | 28,687,880 | [['D02.455.426.559.847.117', 'D04.615.117'], ['E05.196'], ['E01.370.350.515.402.541', 'E05.595.402.541'], ['J01.637.512.850'], ['D01.268.150.250.500', 'J01.637.512.850.500'], ['D12.776'], ['D01.837.700']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Assessment of hyperacusis: the self-rating questionnaire on hypersensitivity to sound]. | BACKGROUND: Hyperacusis is a decreased sound tolerance. The audiological examination includes the loudness discomfort level measurement and the handicap evaluation, so we introduce the Spanish validation of the german sound intolerance questionnaire.OBJECTIVES: To update the concept of hyperacusis and to evaluate its h... | ['Adult', 'Aged', 'Female', 'Humans', 'Hyperacusis', 'Language', 'Male', 'Middle Aged', 'Surveys and Questionnaires'] | 17,036,991 | [['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C09.218.458.505', 'C10.597.751.418.505', 'C23.888.592.763.393.505'], ['F01.145.209.399', 'L01.559'], ['M01.060.116.630'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Treatment of patients with a history of heparin-induced thrombocytopenia and anti-lepirudin antibodies with argatroban. | Patients with heparin-induced thrombocytopenia (HIT) type II require anticoagulation with non-heparin immediate acting anticoagulants. Danaparoid may cross react with HIT-antibodies and lepirudin may generate anti-lepirudin antibodies influencing anticoagulation. We hypothesised, that the synthetic small molecular thro... | ['Aged', 'Antibodies', 'Anticoagulants', 'Arginine', 'Enzyme-Linked Immunosorbent Assay', 'Female', 'Heparin', 'Hirudin Therapy', 'Hirudins', 'Humans', 'Immunoglobulin G', 'Male', 'Middle Aged', 'Pipecolic Acids', 'Platelet Aggregation Inhibitors', 'Recombinant Proteins', 'Sulfonamides', 'Thrombocytopenia'] | 15,976,970 | [['M01.060.116.100'], ['D12.776.124.486.485.114', 'D12.776.124.790.651.114', 'D12.776.377.715.548.114'], ['D27.505.954.502.119'], ['D12.125.068.050', 'D12.125.095.104', 'D12.125.142.087'], ['E05.478.566.350.170', 'E05.478.566.380.360', 'E05.478.583.400.170', 'E05.601.470.350.170', 'E05.601.470.380.360'], ['D09.698.373.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Oxidative stress promotes degradation of the Irr protein to regulate haem biosynthesis in Bradyrhizobium japonicum. | The haem proteins catalase and peroxidase are stress response proteins that detoxify reactive oxygen species. In the bacterium Bradyrhizobium japonicum, expression of the gene encoding the haem biosynthesis enzyme delta-aminolevulinic acid dehydratase (ALAD) is normally repressed by the Irr protein in iron-limited cell... | ['Bacterial Proteins', 'Bradyrhizobium', 'Culture Media', 'Gene Expression Regulation, Bacterial', 'Heme', 'Hydrogen Peroxide', 'Iron', 'Oxidation-Reduction', 'Oxidative Stress', 'Porphobilinogen Synthase', 'Reactive Oxygen Species', 'Receptor, Insulin'] | 16,556,232 | [['D12.776.097'], ['B03.440.400.425.200.090', 'B03.660.050.035.090'], ['D27.720.470.305', 'E07.206'], ['G05.308.300'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Early IL-4 production driving Th2 differentiation in a human in vivo allergic model is mast cell derived. | IL-4 is central to the formation of IgE and the development of Th2 effector cells, both key features of an allergic response. We have examined IL-4 production early in the formation of an allergic response by using a previously established human in vivo model of allergic rhinitis where allergic subjects are challenged ... | ['Adult', 'CD3 Complex', 'Cell Differentiation', 'Female', 'Humans', 'Interleukin-4', 'Kinetics', 'Male', 'Mast Cells', 'Middle Aged', 'Models, Immunological', 'Proto-Oncogene Proteins c-kit', 'Rhinitis, Allergic, Perennial', 'Th2 Cells'] | 9,884,352 | [['M01.060.116'], ['D23.050.301.264.894.095', 'D23.101.100.894.095'], ['G04.152'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D12.644.276.374.465.186', 'D12.776.467.374.465.178', 'D23.529.374.465.186'], ['G01.374.661', 'G02.111.490'], ['A11.329.427', 'A15.382.652'], ['M01.060.116.630'], ['E05.599.395.500'], ['D... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A simple method for assessing the validity of the esophageal balloon technique. | The validity of the conventional esophageal balloon technique as a measure of pleural pressure was tested in 10 subjects in sitting, supine, and lateral positions by occluding the airways at end-expiration and measuring the ratio of changes in esophageal (delta Pes) and mouth pressure (delta Pm) during the ensuing spon... | ['Adult', 'Esophagus', 'Humans', 'Male', 'Manometry', 'Pleura', 'Posture', 'Pressure'] | 7,149,443 | [['M01.060.116'], ['A03.556.875.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.559'], ['A04.716', 'A10.615.789.736'], ['G11.427.695'], ['G01.374.715']] | ['Named Groups [M]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
In situ hybridization to mRNA: from black art to guiding light. | In situ hybridization to mRNA in embryo sections or wholemount embryos is one of the most powerful analytical tools available to the molecular developmental biologist. For many workers, this procedure provides the first insights into the function of newly isolated genes, allowing the formulation of hypotheses and setti... | ['Animals', 'Embryonic and Fetal Development', 'England', 'Female', 'History, 20th Century', 'In Situ Hybridization', 'London', 'Mice', 'Pregnancy', 'RNA, Messenger', 'Research'] | 11,417,907 | [['B01.050'], ['G07.345.500.325', 'G08.686.784.170'], ['Z01.542.363.300'], ['K01.400.504.968'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.475'], ['Z01.433.553', 'Z01.542.363.300.553'], ['B01.050.150.900.649.313.992.635.505.500'], ['... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Temporospatial and kinematic gait alterations during treadmill walking with body weight suspension. | Our purpose was to analyze the effects of selected levels of body weight support (BWS) on lower extremity kinematics of normal subjects at a predetermined treadmill speed. Seventeen non-disabled volunteers walked on a treadmill at 1.25 ms(-1). Temporospatial and kinematic data were collected while various support level... | ['Adult', 'Ankle', 'Biomechanical Phenomena', 'Exercise', 'Female', 'Gait', 'Hip', 'Humans', 'Knee', 'Male', 'Walking', 'Weight-Bearing'] | 12,770,637 | [['M01.060.116'], ['A01.378.610.050'], ['G01.154.090', 'G01.374.089'], ['G11.427.410.698.277', 'I03.350'], ['E01.370.600.250', 'G11.427.410.568.900.750'], ['A01.378.610.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.378.610.450'], ['G11.427.410.568.900', 'G11.427.410.698.277.937', 'I03.350.937', 'I03.450... | ['Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
The efficacy and safety of lanreotide Autogel in patients with acromegaly previously treated with octreotide LAR. | OBJECTIVE: Lanreotide Autogel is a sustained-release aqueous gel formulation supplied in a prefilled syringe, with injection volume <0.5 ml. The aim of this study was to establish the efficacy and safety of Autogel in patients with acromegaly previously treated with octreotide LAR.DESIGN: A 28-week, open, multicentre s... | ['Acromegaly', 'Adult', 'Aged', 'Anti-Inflammatory Agents, Non-Steroidal', 'Antineoplastic Agents, Hormonal', 'Delayed-Action Preparations', 'Female', 'Humans', 'Injections, Intramuscular', 'Male', 'Middle Aged', 'Octreotide', 'Peptides, Cyclic', 'Somatostatin', 'Treatment Outcome'] | 15,080,776 | [['C05.116.132.082', 'C10.228.140.617.738.250.100', 'C19.700.355.179'], ['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D27.505.954.248.169'], ['D26.255.210', 'E02.319.300.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530... | ['Diseases [C]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Lumbar interlaminar epidural injections in central spinal stenosis: preliminary results of a randomized, double-blind, active control trial. | BACKGROUND: Chronic, persistent low back and lower extremity pain is often caused by spinal stenosis. Surgery and other interventions, including epidural injections, have been used to relieve this pain. However, there is little in the medical literature to support interlaminar, or transforaminal epidural injections und... | ['Adult', 'Aged', 'Anesthetics, Local', 'Anti-Inflammatory Agents', 'Back Pain', 'Betamethasone', 'Double-Blind Method', 'Female', 'Fluoroscopy', 'Humans', 'Injections, Epidural', 'Lidocaine', 'Lumbosacral Region', 'Male', 'Middle Aged', 'Spinal Stenosis'] | 22,270,738 | [['M01.060.116'], ['M01.060.116.100'], ['D27.505.696.277.100.200', 'D27.505.696.663.850.025', 'D27.505.954.427.210.100.200'], ['D27.505.954.158'], ['C23.888.592.612.107'], ['D04.210.500.745.432.769.199', 'D04.210.500.908.093'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['E01.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Tubular mechanism for the spontaneous hypercalciuria in laboratory rat. | Recently it has been observed that Ca excretion in laboratory rats does not follow a Gaussian distribution, with approximately 10% of them excreting Ca at a rate of 2 SD above the group mean. This phenomenon has been described as spontaneous hypercalciuria (SH). Our studies were designed to define its mechanism. 48 Wis... | ['Animals', 'Calcium', 'Chlorothiazide', 'Creatinine', 'Cyclic AMP', 'Female', 'Kidney Diseases', 'Kidney Tubules', 'Male', 'Nephrons', 'Parathyroid Hormone', 'Phosphorus', 'Rats', 'Rats, Inbred Strains', 'Sodium'] | 6,288,772 | [['B01.050'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['D02.886.590.700.135.261', 'D02.886.655.500.261', 'D03.633.100.174.261'], ['D03.383.129.308.207'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['C12.777.419', 'C13.351.968.419'], ['A05.810.453.736... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[A case of autoimmune hepatitis following acute hepatitis A]. | The pathogenesis of autoimmune hepatitis (AIH) is unclear, but viral infections have been proposed as a potential trigger in patients with genetic predisposition. We report a case of AIH following acute hepatitis A (AHA). A 57-year-old woman presented with fatigue and pitting edema for last 3 months. She had been diagn... | ['Acute Disease', 'Alanine Transaminase', 'Antibodies, Antinuclear', 'Aspartate Aminotransferases', 'Autoantibodies', 'Azathioprine', 'Female', 'Hepatitis A', 'Hepatitis, Autoimmune', 'Humans', 'Hypergammaglobulinemia', 'Immunosuppressive Agents', 'Liver', 'Middle Aged', 'Prednisolone'] | 21,623,141 | [['C23.550.291.125'], ['D08.811.913.477.700.100'], ['D12.776.124.486.485.114.323.204', 'D12.776.124.790.651.114.323.204', 'D12.776.377.715.548.114.323.204'], ['D08.811.913.477.700.225'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D02.886.759.111', 'D03.633.100.759.5... | ['Diseases [C]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
A case of carcinoid tumor of the middle ear producing peptide hormones. | We report 6th case of carcinoid tumor of the middle ear in a 16-year-old man. The clinical, histologic, immunohistochemical and ultrastructural features are discussed. The tumor in the attic and the tympanic cavity was successfully excised by radical mastoidectomy. Microscopically, the argyrophilic property and neurose... | ['Adolescent', 'Adult', 'Carcinoid Tumor', 'Chromogranins', 'Diagnosis, Differential', 'Ear Neoplasms', 'Ear, Middle', 'Enkephalin, Methionine', 'Female', 'Humans', 'Male', 'Middle Aged', 'Serotonin'] | 3,245,815 | [['M01.060.057'], ['M01.060.116'], ['C04.557.465.625.650.200', 'C04.557.470.200.025.200', 'C04.557.580.625.650.200'], ['D12.776.631.199', 'D12.776.811.185'], ['E01.171'], ['C04.588.443.665.312', 'C09.218.334', 'C09.647.312'], ['A09.246.397'], ['D12.644.400.575.281.381', 'D12.776.631.650.575.281.381'], ['B01.050.150.900... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The impact of progressive semantic loss on reading aloud. | The role of semantics in reading aloud remains controversial. To explore this issue, the current study examined the impact of semantic loss on reading-aloud performance in 7 patients with semantic dementia. The results revealed a heterogenous pattern of reading difficulties. Of the patients, 2 selectively made errors o... | ['Aged', 'Aged, 80 and over', 'Attention', 'Cognition Disorders', 'Dementia', 'Female', 'Humans', 'Male', 'Memory Disorders', 'Neuropsychological Tests', 'Phonation', 'Phonetics', 'Reaction Time', 'Reading', 'Severity of Illness Index', 'Vocabulary'] | 18,416,487 | [['M01.060.116.100'], ['M01.060.116.100.080'], ['F02.830.104.214'], ['F03.615.250'], ['C10.228.140.380', 'F03.615.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.525', 'C23.888.592.604.529', 'F01.700.625'], ['F04.711.513'], ['G09.772.585'], ['L01.559.598.518'], ['E05.796.817', 'F02.830.650', 'F04.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Quadriceps function and training after knee ligament surgery. | A follow-up study of 30 patients operated on for knee ligament injuries was performed with measurements of maximal isometric and isokinetic (angular velocity 30, 42, 120 degrees/s) torque for knee extension and muscle biopsy from vastus laternalis. The maximal torque values of the operated side were reduced in spite of... | ['Adolescent', 'Adult', 'Exercise Therapy', 'Humans', 'Isometric Contraction', 'Knee Joint', 'Ligaments, Articular', 'Middle Aged', 'Muscular Atrophy', 'Physical Exertion'] | 7,188,589 | [['M01.060.057'], ['M01.060.116'], ['E02.760.169.063.500.387', 'E02.779.483', 'E02.831.535.483'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.494.472'], ['A02.835.583.475'], ['A02.513.514', 'A02.835.583.512', 'A10.165.669.514'], ['M01.060.116.630'], ['C10.597.613.612', 'C23.300.070.500', 'C23.888.592.608... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Development of Dietary Supplement Label Database in Italy: Focus of FoodEx2 Coding. | The sector of food supplements is certainly varied and growing: an ever wider offer of new products is launched on the market every year. This is reflected in new reorganization of drug companies and new marketing strategies, in the adoption of new production technologies with resulting changes in dietary supplements r... | ['Data Management', 'Databases, Factual', 'Dietary Supplements', 'Food', 'Food Labeling', 'Humans', 'Italy', 'Product Labeling'] | 31,892,267 | [['L01.399.375', 'L01.453.233', 'L01.470.563'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['G07.203.300.456', 'J02.500.456'], ['G07.203.300', 'J02.500'], ['J01.576.423.850.600.400', 'J01.576.761.400.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.542.489'], ['J01.576.761.700']] | ['Information Science [L]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 |
Inhibiting mitochondrial â-oxidation selectively reduces levels of nonenzymatic oxidative polyunsaturated fatty acid metabolites in the brain. | Sch?nfeld and Reiser recently hypothesized that fatty acid â-oxidation is a source of oxidative stress in the brain. To test this hypothesis, we inhibited brain mitochondrial â-oxidation with methyl palmoxirate (MEP) and measured oxidative polyunsaturated fatty acid (PUFA) metabolites in the rat brain. Upon MEP treatme... | ['Animals', 'Asphyxia', 'Brain', 'Epoxy Compounds', 'Fatty Acids, Unsaturated', 'Male', 'Microwaves', 'Mitochondria', 'Oxidation-Reduction', 'Oxidative Stress', 'Propionates', 'Rats', 'Rats, Sprague-Dawley'] | 24,326,387 | [['B01.050'], ['C23.550.260.095', 'C26.103'], ['A08.186.211'], ['D02.355.291.411'], ['D10.251.355'], ['G01.358.500.505.810.500', 'G01.750.250.810.500', 'G01.750.770.721.500'], ['A11.284.430.214.190.875.564', 'A11.284.835.626'], ['G02.700', 'G03.295.531'], ['G03.673', 'G07.775.750'], ['D02.241.081.751', 'D10.251.400.706... | ['Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Oral habits, dental trauma, and occlusal characteristics among 4- to 12-year-old institutionalized orphan children in Riyadh, Saudi Arabia. | The aim of this study was to assess the oral habit practices, dental trauma, and occlusal characteristics of 4- to 12-year-old orphans living in governmental orphanages in Riyadh. This cross-sectional study was conducted in three government orphanages and three ordinary schools. All 90 orphans, residing in the orphanag... | ['Child', 'Child, Orphaned', 'Child, Preschool', 'Cross-Sectional Studies', 'Female', 'Fingersucking', 'Habits', 'Humans', 'Male', 'Malocclusion', 'Nail Biting', 'Saudi Arabia', 'Self Mutilation', 'Surveys and Questionnaires', 'Tooth Injuries'] | 27,118,440 | [['M01.060.406'], ['M01.108'], ['M01.060.406.448'], ['E05.318.372.500.875', 'N05.715.360.330.500.875', 'N06.850.520.450.500.875'], ['F01.145.466.263'], ['F01.145.466'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C07.793.494'], ['F01.145.466.554'], ['Z01.252.245.500.750'], ['C26.780', 'F01.145.126.980.750'], ['E... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Eccentric contraction induces inflammatory responses in rat skeletal muscle: role of tumor necrosis factor-alpha. | Eccentric contraction (EC) is known to elicit inflammation and damage in skeletal muscle. Proinflammatory cytokine TNF-alpha plays an important role in this pathogenesis, but the time course of its response to EC and the regulatory mechanisms involved are not clear. The purpose of the study is twofold: 1) to investigat... | ['Aconitate Hydratase', 'Animals', 'Creatine Kinase', 'Endotoxemia', 'Female', 'Gene Expression', 'Hydrogen Peroxide', 'Lipopolysaccharides', 'Muscle Contraction', 'Muscle, Skeletal', 'Myositis', 'NF-kappa B', 'Oxidative Stress', 'Peroxidase', 'Physical Exertion', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Reac... | 20,007,518 | [['D08.811.520.241.300.050'], ['B01.050'], ['D08.811.913.696.640.150'], ['C01.757.100.275', 'C01.861.375', 'C23.550.470.790.500.100.275'], ['G05.297'], ['D01.248.497.158.685.750.424', 'D01.339.431.374.424', 'D01.650.550.750.400', 'D02.389.338.253'], ['D09.400.500', 'D09.698.718.450', 'D10.494', 'D23.050.161.616.525', '... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Racial disparities and sex-based outcomes differences after severe injury. | BACKGROUND: Controversy exists about the mechanisms responsible for sex-based outcomes differences post-injury. X-chromosome-linked immune response pathway polymorphisms represent a potential mechanism resulting in sex-based outcomes differences post-injury. The prevalence of these variants is known to differ across ra... | ['Adult', 'Aged', 'Confidence Intervals', 'Continental Population Groups', 'Female', 'Health Status Disparities', 'Healthcare Disparities', 'Humans', 'Male', 'Middle Aged', 'Odds Ratio', 'Retrospective Studies', 'Risk Assessment', 'Risk Factors', 'Sex Distribution', 'Sex Factors', 'Trauma Severity Indices', 'United Sta... | 22,521,668 | [['M01.060.116'], ['M01.060.116.100'], ['E05.318.740.275', 'N05.715.360.750.220', 'N06.850.520.830.275'], ['M01.686.508'], ['I01.240.425.675', 'N01.224.425.437', 'N06.850.505.400.425.675'], ['N04.590.374.380', 'N05.300.493'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.740.600.600', ... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
A case of vocal cord nodules masking essential (voice) tremor. | Essential tremor is a progressive, potentially debilitating disorder that may be manifested in the voice only. In the case we report, the signs occurred concurrently with the voice characteristics of vocal cord nodules but were subtle. The mildness of the voice tremor precluded treatment at this time, although the resu... | ['Diagnosis, Differential', 'Female', 'Humans', 'Laryngeal Neoplasms', 'Middle Aged', 'Tremor', 'Vocal Cords', 'Voice Disorders', 'Voice Quality'] | 7,053,750 | [['E01.171'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.443.665.481', 'C08.360.369', 'C08.785.481', 'C09.400.369', 'C09.647.481'], ['M01.060.116.630'], ['C10.597.350.850', 'C23.888.592.350.850'], ['A04.329.364.737'], ['C08.360.940', 'C09.400.940', 'C10.597.975', 'C23.888.592.979'], ['G09.772.925.960']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Named Groups [M]', 'Anatomy [A]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Vertical augmentation of the posterior atrophic mandible by interpositional grafts in a split-mouth design: a human tomography evaluation pilot study. | OBJECTIVE: Using computed tomography, to compare vertical and volumetric bone augmentation after interposition grafting with bovine bone mineral matrix (GEISTLICH BIO-OSS® ) or hydroxyapatite/tricalcium phosphate (STRAUMANN® BONECERAMIC) for atrophic posterior mandible reconstruction through segmental osteotomy.MATERIA... | ['Alveolar Ridge Augmentation', 'Atrophy', 'Bone Substitutes', 'Cone-Beam Computed Tomography', 'Female', 'Humans', 'Hydroxyapatites', 'Male', 'Mandible', 'Minerals', 'Pilot Projects'] | 27,704,640 | [['E04.545.550.100', 'E06.645.550.100'], ['C23.300.070'], ['D25.130.325', 'J01.637.051.130.325'], ['E01.370.350.700.810.810.490', 'E01.370.350.825.810.810.399'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.029.260.700.675.374.075.025.300', 'D01.146.360.050.300', 'D01.578.122.477', 'D01.695.625.675.650.075.02... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Health Care [N]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Quality monitoring of soft-copy displays for medical radiography. | As presentation of medical radiographic images on soft-copy displays (cathode ray tubes) becomes increasingly prevalent in electronic radiography, methods of quality assurance must be developed to ensure that radiologists can effectively transfer film-based reading skills. Luminance measurements provide the basis for e... | ['Computer Peripherals', 'Data Display', 'Humans', 'Quality Control', 'Radiology Information Systems'] | 1,520,742 | [['L01.224.230.260.115'], ['F02.784.412.221', 'L01.296'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['J01.897.608'], ['N04.452.515.825']] | ['Information Science [L]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Technology, Industry, and Agriculture [J]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 |
Extracellular matrix rigidity controls podosome induction in microvascular endothelial cells. | BACKGROUND INFORMATION: Podosomes are actin-based structures involved in cell adhesion, migration, invasion and extracellular matrix degradation. They have been described in large vessel endothelial cells, but nothing is known concerning microvascular endothelial cells. Here, we focussed on liver sinusoidal endothelial... | ['Actin Cytoskeleton', 'Cell Adhesion', 'Endothelial Cells', 'Extracellular Matrix', 'Humans', 'Liver', 'Microvessels', 'Signal Transduction', 'Transforming Growth Factor beta', 'Vascular Endothelial Growth Factor A'] | 23,106,484 | [['A11.284.430.214.190.750.050'], ['G04.022'], ['A11.436.275'], ['A11.284.295.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A03.620'], ['A07.015.461'], ['G02.111.820', 'G04.835'], ['D12.644.276.374.687', 'D12.644.276.954.775', 'D12.776.467.374.687', 'D12.776.467.942.775', 'D23.529.374.687', 'D23.529.942.775... | ['Anatomy [A]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Use of glyceroltriheptanoate as marker for processed animal by-products: development and validation of an analytical method. | A recently published European Regulation requires that the artificial marker, glycerol triheptanoate (GTH), be added to processed animal by-product (ABPs) prohibited from entering the food chain. The objective of this new requirement is to allow full traceability and ensure that these materials are disposed of in a pro... | ['Animals', 'Food Chain', 'Gas Chromatography-Mass Spectrometry', 'Limit of Detection', 'Meat Products', 'Reproducibility of Results', 'Triglycerides'] | 19,680,920 | [['B01.050'], ['G16.500.275.157.250', 'N06.230.124.250'], ['E05.196.181.349.500', 'E05.196.566.500'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500'], ['G07.203.300.600.500', 'J02.500.600.500'], ['E05.318.370.725', 'E05.337.851', 'N05.715.360.325.685', 'N06.850.520.445.725'], ['D10.351.801... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 |
Biomechanical analysis of axial distraction mobilization of the glenohumeral joint--a cadaver study. | The axial distraction mobilization techniques are frequently employed for treating patients with joint hypomobility. However, there is a lack of basic biomechanical studies and description of this procedure. The purpose of this study was to analyze humeral head displacement while performing an axial distraction mobiliz... | ['Adult', 'Biomechanical Phenomena', 'Bursitis', 'Cadaver', 'Female', 'Humans', 'Male', 'Musculoskeletal Manipulations', 'Range of Motion, Articular', 'Shoulder Impingement Syndrome', 'Shoulder Joint'] | 18,805,038 | [['M01.060.116'], ['G01.154.090', 'G01.374.089'], ['C05.550.251'], ['C23.550.260.224'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.190.599', 'E02.779.867', 'E02.831.535.867'], ['E01.370.600.700', 'G11.427.760'], ['C05.550.840', 'C26.803.500'], ['A02.835.583.748']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Human thymocytes become lineage committed at an early postselection CD69+ stage, before the onset of functional maturation. | Mature functional CD4 or CD8 single positive (SP) thymocytes differentiate from immature CD4+ 8+ double positive (DP) precursors through a process of positive selection and terminal differentiation. To study CD4/CD8 lineage commitment, human postselection CD69+ thymocytes were separated into distinct subpopulations bas... | ['Animals', 'Antigens, CD', 'Antigens, CD1', 'Antigens, Differentiation, T-Lymphocyte', 'CD3 Complex', 'CD4 Antigens', 'CD4-Positive T-Lymphocytes', 'CD8 Antigens', 'CD8-Positive T-Lymphocytes', 'Cell Differentiation', 'Child', 'Child, Preschool', 'Coculture Techniques', 'DNA-Binding Proteins', 'Fetus', 'Genes, RAG-1',... | 9,550,395 | [['B01.050'], ['D23.050.301.264.035', 'D23.101.100.110'], ['D23.050.301.264.035.100', 'D23.050.301.264.894.080', 'D23.101.100.110.100', 'D23.101.100.894.080'], ['D23.050.301.264.894', 'D23.101.100.894'], ['D23.050.301.264.894.095', 'D23.101.100.894.095'], ['D12.776.543.750.705.852.420.810.500', 'D12.776.543.750.830.700... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Serotonin receptor blockade potentiates behavioural effects of beta-phenylethylamine. | The 5-hydroxytryptamine (5HT) receptor blocker, methysergide (10 mg/kg), was found to potentiate the behavioural effects of beta-phenylethylamine (PEA) (at doses between 20 and 60 mg/kg) on food reinforced schedule-maintained behaviour in two separate experiments involving a fixed interval 2 min schedule and a fixed ra... | ['Animals', 'Avoidance Learning', 'Behavior, Animal', 'Drug Synergism', 'Male', 'Methysergide', 'Phenethylamines', 'Rats', 'Receptors, Serotonin'] | 7,155,309 | [['B01.050'], ['F02.463.425.097', 'F02.463.785.373.173'], ['F01.145.113'], ['G07.690.773.968.477'], ['D03.132.327.287.689', 'D03.633.400.439.689'], ['D02.092.471.683'], ['B01.050.150.900.649.313.992.635.505.700'], ['D12.776.543.750.670.800', 'D12.776.543.750.695.800', 'D12.776.543.750.720.850']] | ['Organisms [B]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Cost approach of health care entity intangible asset valuation. | In the valuation synthesis and conclusion process, the analyst should consider the following question: Does the selected valuation approach(es) and method(s) accomplish the analyst's assignment? Also, does the selected valuation approach and method actually quantify the desired objective of the intangible asset analysi... | ['Accounting', 'Costs and Cost Analysis', 'Data Collection', 'Financial Management', 'Health Facility Administration', 'Humans'] | 23,971,139 | [['N03.219.463.030'], ['N03.219.151'], ['E05.318.308', 'L01.399.250', 'N05.715.360.300', 'N06.850.520.308'], ['N03.219.463'], ['N02.278.216', 'N04.452.442'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 |
Comparison of two survey methodologies to assess vaccination coverage. | BACKGROUND: Measuring vaccination coverage permits evaluation and appropriate targeting of vaccination services. The cluster survey methodology developed by the World Health Organization, known as the 'Expanded Program on Immunization (EPI) methodology', has been used worldwide to assess vaccination coverage; however, ... | ['Adolescent', 'Child', 'Child, Preschool', 'Epidemiologic Methods', 'Ethiopia', 'Female', 'Humans', 'Immunization Programs', 'Infant', 'Male', 'Measles', 'Measles Vaccine', 'Socioeconomic Factors', 'Vaccination'] | 17,420,165 | [['M01.060.057'], ['M01.060.406'], ['M01.060.406.448'], ['E05.318', 'N06.850.520'], ['Z01.058.290.120.310'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N02.421.726.608'], ['M01.060.703'], ['C01.925.782.580.600.500.500'], ['D20.215.894.899.404'], ['I01.880.853.996', 'N01.824'], ['E02.095.465.425.400.530.890', 'E... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Anthropology, Education, Sociology, and Social Phenomena [I]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Notch signaling suppresses IgH gene expression in chicken B cells: implication in spatially restricted expression of Serrate2/Notch1 in the bursa of Fabricius. | The bursa of Fabricius is a central organ for chicken B cell development and provides an essential microenvironment for expansion of the B cell pool and for generation of a diversified B cell repertoire. We report here that genes encoding the Notch family of transmembrane proteins, key regulators of cell fate determina... | ['Amino Acid Sequence', 'Animals', 'B-Lymphocytes', 'Basic Helix-Loop-Helix Transcription Factors', 'Bursa of Fabricius', 'Carrier Proteins', 'Cell Differentiation', 'Cell Line', 'Cell Line, Transformed', 'Chickens', 'Enhancer Elements, Genetic', 'Gene Expression Regulation, Developmental', 'Genes, Immunoglobulin', 'Hu... | 11,207,282 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['A11.063.438', 'A11.118.637.555.567.562', 'A15.145.229.637.555.567.562', 'A15.382.032.438', 'A15.382.490.555.567.562'], ['D12.776.260.103', 'D12.776.930.125'], ['A10.549.175', 'A13.163', 'A15.382.520.604.114'], ['D12.776.157'], ['G04.152'], ['A11.251.210'], ['A... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
[Medical palliative therapy of meningiosis carcinomatosa of breast carcinoma with dissociated response in lumbar methotrexate instillation]. | CASE REPORT: We report the case of a 51-year-old woman who suffered from breast cancer and developed meningeal carcinomatosis of the brain stem with deafness and blindness. Radiotherapy was given but led to remarkable deterioration of the condition and strong headache. We performed intrathecal therapy with methotrexate... | ['Adenocarcinoma', 'Breast Neoplasms', 'Female', 'Humans', 'Injections, Spinal', 'Magnetic Resonance Imaging', 'Meningeal Neoplasms', 'Methotrexate', 'Middle Aged', 'Neoplasm Staging', 'Palliative Care', 'Treatment Outcome'] | 11,603,118 | [['C04.557.470.200.025'], ['C04.588.180', 'C17.800.090.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.319.267.530.580'], ['E01.370.350.825.500'], ['C04.588.614.250.580', 'C10.551.240.500'], ['D03.633.100.733.631.192.500'], ['M01.060.116.630'], ['E01.789.625'], ['E02.760.666', 'N02.421.585.666'], ['E01.78... | ['Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
An active-site cysteine of sorghum leaf NADP-malate dehydrogenase studied by site-directed mutagenesis. | The chloroplast NADP-malate dehydrogenase is activated through the reduction of two different disulfides per subunit. The activated enzyme, as well as a permanently active mutant where all four regulatory cysteines were replaced are still sensitive to thiol reagents. This observation suggested the presence of an additi... | ['Base Sequence', 'Binding Sites', 'Cysteine', 'Enzyme Activation', 'Iodoacetamide', 'Kinetics', 'Malate Dehydrogenase', 'Malate Dehydrogenase (NADP+)', 'Molecular Sequence Data', 'Molecular Weight', 'Mutagenesis, Site-Directed', 'Plant Leaves', 'Poaceae', 'Recombinant Fusion Proteins', 'Sulfhydryl Reagents'] | 8,612,735 | [['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G02.111.570.120'], ['D02.886.030.230', 'D02.886.489.155', 'D12.125.154.299', 'D12.125.166.230'], ['G02.111.263', 'G03.328'], ['D02.065.064.400', 'D02.241.081.018.110.400', 'D02.241.081.018.487.249', 'D02.455.526.581.247.249'], ['G01.374.661', 'G02.111.490'],... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Action of treosulfan in myelin-oligodendrocyte-glycoprotein-induced experimental autoimmune encephalomyelitis and human lymphocytes. | Treosulfan (dihydroxybusulfane, DHB, L-threitol-1,4-bis [methane sulfonate]) is a cytostatic alkylating agent with a favorable profile of side effects. Myelin-oligodendrocyte-glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE) induced in DA (RT1(av1)) rats resembles multiple sclerosis (MS) in man... | ['Amino Acid Sequence', 'Animals', 'Antigen Presentation', 'Antigens, Differentiation, T-Lymphocyte', 'Apoptosis', 'Bone Marrow Cells', 'Busulfan', 'Cell Differentiation', 'Cytokines', 'Dendritic Cells', 'Encephalomyelitis, Autoimmune, Experimental', 'Female', 'Humans', 'Immunosuppressive Agents', 'Injections, Intrader... | 14,597,095 | [['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G12.119', 'G12.450.050.400.070'], ['D23.050.301.264.894', 'D23.101.100.894'], ['G04.146.954.035'], ['A11.148', 'A15.378.316'], ['D02.033.455.125.125', 'D02.455.326.146.100.050.500.100', 'D02.886.645.600.055.050.510.100'], ['G04.152'], ['D12.644.276.374', 'D12.... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Intravesical self-tying knots in suprapubic catheters: a report of two cases. | We present two cases in which intravesical, self-tying knots occurred when the Cystofix catheter was used for suprapubic catheterization in two male boys admitted for hypospadias surgery. This complication of suprapubic catheterization is most likely due to the pigtail end of the catheter, and should be considered when... | ['Catheters, Indwelling', 'Device Removal', 'Equipment Design', 'Equipment Failure', 'Humans', 'Hypospadias', 'Male', 'Urinary Catheterization'] | 17,853,022 | [['E07.132.500'], ['E04.199'], ['E05.320'], ['E05.325'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C12.294.494.400', 'C12.706.516', 'C13.351.875.466', 'C16.131.939.516'], ['E01.370.390.820', 'E02.148.947', 'E05.157.500']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Methods of augmentation of antidepressant therapy (on the model of complex therapy with the inclusion of actovegin) in gerontopsychiatric hospital]. | AIM: Increasing the effectiveness of treatment of elderly depressed patients in the conditions of the gerontopsychiatric hospital by augmentation of actovegin to antidepressants of new generations (fluvoxamine, venlafaxine or agomelatine).MATERIAL AND METHODS: The efficacy of the therapy was compared in two groups of 2... | ['Aged', 'Antidepressive Agents', 'Heme', 'Humans', 'Middle Aged'] | 30,346,435 | [['M01.060.116.100'], ['D27.505.954.427.700.122'], ['D03.383.129.578.840.500.640.587', 'D03.633.400.909.500.640.587', 'D04.345.783.500.640.587', 'D23.767.727.640.587'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Disruption of the GH Receptor Gene in Adult Mice Increases Maximal Lifespan in Females. | GH and IGF-1 are important for a variety of physiological processes including growth, development, and aging. Mice with reduced levels of GH and IGF-1 have been shown to live longer than wild-type controls. Our laboratory has previously found that mice with a GH receptor gene knockout (GHRKO) from conception exhibit lo... | ['Adiposity', 'Animals', 'Female', 'Growth Hormone', 'Insulin Resistance', 'Insulin-Like Growth Factor I', 'Longevity', 'Male', 'Mice', 'Mice, Knockout', 'Receptors, Somatotropin', 'Sex Factors', 'Signal Transduction'] | 27,732,088 | [['E01.370.600.115.100.062.500', 'G02.111.130.134.500', 'G03.180.134.500', 'G07.100.049.134.500'], ['B01.050'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['C18.452.394.968.500', 'G07.690.773.984.617'], ['D12.644.276.937.400', 'D12.776.124.862.400', 'D12.776.467.937.400', 'D23.529.937.400'], ['G07.345.124.... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Acute conduction block associated with experimental antiserum-mediated demyelination of peripheral nerve. | Intraneural injection of antisera from rabbits with high antigalactocerebroside antibody levels into rat sciatic nerve produced acute nerve conduction block. This was first apparent in some motor axons between 30 and 60 minutes after injection and progressed to completion within 2 to 4 hours. Concurrent morphological e... | ['Animals', 'Demyelinating Diseases', 'Encephalomyelitis, Autoimmune, Experimental', 'Evoked Potentials', 'Immune Sera', 'Male', 'Myelin Sheath', 'Nerve Fibers, Myelinated', 'Neural Conduction', 'Peripheral Nervous System Diseases', 'Rats', 'Rats, Inbred Strains', 'Sciatic Nerve', 'Tibial Nerve'] | 6,285,800 | [['B01.050'], ['C10.314'], ['C10.114.703.300', 'C10.228.140.695.562.250', 'C10.314.350.250', 'C20.111.258.625.300', 'E05.598.500.500.500'], ['G07.265.216.500', 'G11.561.200.500'], ['A12.207.152.846.500', 'D12.776.124.486.485.114.573', 'D12.776.124.790.651.114.573', 'D12.776.377.715.548.114.573', 'D20.215.401'], ['A08.6... | ['Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Diversity and Function of Maternal HIV-1-Specific Antibodies at the Time of Vertical Transmission. | Infants of HIV-positive mothers can acquire HIV infection by various routes, but even in the absence of antiviral treatment, the majority of these infants do not become infected. There is evidence that maternal antibodies provide some protection from infection, but gestational maternal antibodies have not yet been char... | ['AIDS Vaccines', 'Antibodies, Monoclonal', 'Antibodies, Neutralizing', 'Antibody Specificity', 'Epitopes', 'Female', 'HIV Antibodies', 'HIV Infections', 'HIV-1', 'Humans', 'Infant', 'Infectious Disease Transmission, Vertical', 'Pregnancy', 'Pregnancy Complications, Infectious', 'env Gene Products, Human Immunodeficien... | 32,075,936 | [['D20.215.894.899.050'], ['D12.776.124.486.485.114.224', 'D12.776.124.790.651.114.224', 'D12.776.377.715.548.114.224'], ['D12.776.124.486.485.114.244', 'D12.776.124.790.651.114.244', 'D12.776.377.715.548.114.244'], ['G12.100'], ['D23.050.550'], ['D12.776.124.486.485.114.254.150.440', 'D12.776.124.790.651.114.254.150.4... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Disturbed sleep patterns in elders with mild cognitive impairment: the role of memory decline and ApoE å4 genotype. | Sleep disturbances are prevalent in patients with Alzheimer' disease (AD), being one of the most troubling symptoms during the progression of disease. However, little research has been made to determine if impaired sleep patterns appear years before AD diagnosis. This study tries to shed light on this issue by performi... | ['Aged', 'Apolipoprotein E4', 'Cognitive Dysfunction', 'Female', 'Humans', 'Male', 'Memory Disorders', 'Middle Aged', 'Sleep Wake Disorders'] | 22,211,488 | [['M01.060.116.100'], ['D10.532.091.500.750', 'D12.776.070.400.500.750', 'D12.776.521.120.500.750'], ['F03.615.250.700'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C10.597.606.525', 'C23.888.592.604.529', 'F01.700.625'], ['M01.060.116.630'], ['C10.886', 'C23.888.592.796', 'F03.870']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Characterization of polylactides with different stereoregularity using electrospray ionization ion mobility mass spectrometry. | We investigated the effect of stereoregularity on the gas-phase conformations of linear and cyclic polylactides (PLA) using electrospray ionization ion mobility mass spectrometry (ESI-IM-MS) combined with molecular dynamics simulations. IM-MS analysis of PLA ions shows intriguing difference between the collision cross ... | ['Models, Molecular', 'Molecular Conformation', 'Polyesters', 'Spectrometry, Mass, Electrospray Ionization', 'Stereoisomerism'] | 25,001,385 | [['E05.599.595'], ['G02.111.570.820'], ['D05.750.728', 'D25.720.728', 'J01.637.051.720.728'], ['E05.196.566.600'], ['G02.607.445.682']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
[Lymphectomy for well differentiated or "aggressive" thyroid malignancies. Indications, complications and results of our experience]. | The aim of this retrospective study was to assess the role of lymphectomy in the treatment of well differentiated and aggressive carcinomas of the thyroid gland. From 1987 to 2002, 231 patients were operated on in our Division; 97 were male (42%) and 134 female (58%), with a mean age of 48 years (range 17-45). One hund... | ['Adolescent', 'Adult', 'Aged', 'Female', 'Humans', 'Lymph Node Excision', 'Lymphatic Metastasis', 'Male', 'Middle Aged', 'Retrospective Studies', 'Thyroid Neoplasms'] | 15,916,139 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E04.446'], ['C04.697.650.560', 'C23.550.727.650.560'], ['M01.060.116.630'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.500.750.825', 'N06.850.520.450.500... | ['Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The rulB gene of plasmid pWW0 is a hotspot for the site-specific insertion of integron-like elements found in the chromosomes of environmental Pseudomonas fluorescens group bacteria. | The rulAB operon of Pseudomonas spp. confers fitness traits on the host and has been suggested to be a hotspot for insertion of mobile elements that carry avirulence genes. Here, for the first time, we show that rulB on plasmid pWW0 is a hotspot for the active site-specific integration of related integron-like elements... | ['Bacterial Proteins', 'Base Sequence', 'Chromosomes, Bacterial', 'Conserved Sequence', 'Genetic Fitness', 'Genomic Islands', 'Integrons', 'Microbial Viability', 'Molecular Sequence Data', 'Open Reading Frames', 'Operon', 'Plasmids', 'Pseudomonas fluorescens'] | 24,286,439 | [['D12.776.097'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.284.187.190', 'A20.812', 'G05.360.162.190'], ['G02.111.570.580'], ['G05.347'], ['G02.111.570.080.708.330.330', 'G05.360.080.708.330.330', 'G05.360.340.024.425.500'], ['G02.111.570.080.708.330.200.500'], ['G06.580'], ['L01.453.245.667'], ... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Calcium transport across the pars recta of cortical segment 2 proximal tubules. | Partes rectae of cortical segment 2 proximal tubules were dissected from rabbit kidneys and perfused in vitro. Ca concentrations of perfused and collected fluids were measured by continuous-flow microcolorimetry. Epithelial Ca permeability (P) was estimated from the bath-to-lumen movement of 45Ca. The transepithelial v... | ['Absorption', 'Animals', 'Biological Transport', 'Calcium', 'Cold Temperature', 'Epithelium', 'Female', 'Hydrogen-Ion Concentration', 'Kidney Cortex', 'Kidney Tubules, Proximal', 'Osmolar Concentration', 'Rabbits'] | 3,766,746 | [['G01.015', 'G02.010', 'G03.015', 'G03.787.024', 'G07.690.725.015'], ['B01.050'], ['G03.143'], ['D01.268.552.100', 'D01.552.539.288', 'D23.119.100'], ['G01.906.595.272', 'G16.500.275.063.725.710.300', 'G16.500.750.775.710.300', 'N06.230.300.100.725.154', 'N06.230.300.100.725.710.300'], ['A10.272'], ['G02.300'], ['A05.... | ['Phenomena and Processes [G]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Agrobacterium-Mediated Transformation of Solanum tuberosum L., Potato. | Potato is considered the fourth most important food crop in the world, and the most important non-cereal crop. Potato is transformed using Agrobacterium tumefaciens with relative ease. Several improvements have been made in the last 20 years with respect to tissue culture, transformation, and regeneration of potato. Th... | ['Agrobacterium tumefaciens', 'Genetic Vectors', 'Plants, Genetically Modified', 'Plasmids', 'Solanum tuberosum', 'Transformation, Genetic'] | 30,415,339 | [['B03.440.400.425.700.024.050', 'B03.660.050.662.024.500'], ['G05.360.337'], ['B01.650.520', 'B05.620.600'], ['G05.360.600'], ['B01.650.940.800.575.912.250.908.500.725.777'], ['G05.728.865']] | ['Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Dynamics and physiological significance of GABA-system activation in brain and cardiac muscle during emotional-pain stress]. | Effect of emotional-painful stress (EPS) on activity of the gamma-aminobutyric acid (GABA) system was studied in animal brain hemispheres and heart muscle. Activation of the GABA-system, developed in brain and heart tissues after EPS, exhibited various physiological importance in the tissues. In brain tissue activation... | ['4-Aminobutyrate Transaminase', 'Animals', 'Brain', 'Female', 'Glutamate Decarboxylase', 'Humans', 'Myocardium', 'Pain', 'Rats', 'Stress, Physiological', 'Stress, Psychological', 'gamma-Aminobutyric Acid'] | 7,193,380 | [['D08.811.913.477.700.200'], ['B01.050'], ['A08.186.211'], ['D08.811.520.224.125.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.633.580', 'A07.541.704', 'A10.690.552.750'], ['C23.888.592.612', 'F02.830.816.444', 'G11.561.790.444'], ['B01.050.150.900.649.313.992.635.505.700'], ['G07.775'], ['F01.145.126.... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
[Mycoplasma pneumoniae myopericarditis in children]. | Mycoplasma pneumoniae myocarditis is a rare condition, potentially very serious and seldom described in children. It is classically attributed to direct invasion or to an indirect immunological mechanism. The authors report the case of a 10 year old boy with myopericarditis, proved by authentic seroconversion, complica... | ['Child', 'Glucocorticoids', 'Humans', 'Male', 'Mycoplasma Infections', 'Mycoplasma pneumoniae', 'Myocarditis', 'Pericarditis', 'Treatment Outcome'] | 16,802,744 | [['M01.060.406'], ['D06.472.040.543', 'D27.505.696.399.472.488'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C01.150.252.400.610.610'], ['B03.440.860.580.553.553.650'], ['C14.280.238.625'], ['C14.280.720'], ['E01.789.800', 'N04.761.559.590.800', 'N05.715.360.575.575.800']] | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Child and adolescent injury in the United States: how occupational injuries fit in. | Injury is the leading cause of death in adolescence, with the highest rates for 15- to 19-year-olds, an age span also marked, for many, by entry into the workforce. Occupational injuries affecting youth occur in the context of the larger problem of injury affecting children and adolescents. An understanding of the broa... | ['Accident Prevention', 'Accidents, Occupational', 'Adolescent', 'Age Distribution', 'Child', 'Homicide', 'Humans', 'United States', 'Wounds and Injuries'] | 8,238,030 | [['N06.850.135.060'], ['N06.850.135.240'], ['M01.060.057'], ['I01.240.050', 'N01.224.033', 'N06.850.505.400.050'], ['M01.060.406'], ['I01.198.240.470', 'I01.880.735.344'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.107.567.875'], ['C26']] | ['Health Care [N]', 'Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Two-mechanism peak concentration model for cellular pharmacodynamics of Doxorubicin. | A mathematical model is presented for the cellular uptake and cytotoxicity of the anticancer drug doxorubicin. The model assumes sigmoidal, Hill-type dependence of cell survival on drug-induced damage. Experimental evidence indicates distinct intracellular and extracellular mechanisms of doxorubicin cytotoxicity. Drug-... | ['Animals', 'Antibiotics, Antineoplastic', 'Area Under Curve', 'Cell Line, Tumor', 'Cell Survival', 'Dose-Response Relationship, Drug', 'Doxorubicin', 'Humans', 'Models, Biological', 'Models, Theoretical', 'Statistics as Topic', 'Time Factors'] | 16,026,650 | [['B01.050'], ['D27.505.954.248.106'], ['E05.318.740.200', 'G03.787.101', 'G07.690.725.064', 'N06.850.520.830.200'], ['A11.251.210.190', 'A11.251.860.180'], ['G04.346'], ['G07.690.773.875', 'G07.690.936.500'], ['D02.455.426.559.847.562.050.200.175', 'D04.615.562.050.200.175', 'D09.408.051.059.200.175'], ['B01.050.150.9... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Disciplines and Occupations [H]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Epicardial coronary artery constriction with intravenous ethanol. | Although in vitro studies have demonstrated ethanol-induced coronary artery constriction, in vivo reports suggest an ethanol-related coronary dilator effect with increases in coronary blood flow. The principal difference in these studies is the demonstration of epicardial coronary constriction with ethanol, while dilat... | ['Alcoholism', 'Animals', 'Coronary Vessels', 'Dogs', 'Endothelium, Vascular', 'Ethanol', 'Infusions, Intravenous', 'Vascular Resistance', 'Vasoconstriction'] | 2,707,911 | [['C25.775.100.250', 'F03.900.100.350'], ['B01.050'], ['A07.015.114.269', 'A07.015.908.194'], ['B01.050.150.900.649.313.750.250.216.200'], ['A07.015.700.500', 'A10.272.491.355'], ['D02.033.375'], ['E02.319.267.082.500', 'E02.319.267.510.590'], ['G09.330.380.921'], ['G09.330.380.925']] | ['Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Activation of muscle phosphofructokinase by fructose 2,6-bisphosphate and fructose 1,6-bisphosphate is differently affected by other regulatory metabolites. | Fructose-2,6-P2 and fructose-1,6-P2 are strong activators of muscle phosphofructokinase. They have been shown to be competitive in binding studies, and it is generally thought that they affect the physical and catalytic properties of the enzyme in the same manner. However, there are indications in published data that t... | ['Adenosine Monophosphate', 'Adenosine Triphosphate', 'Animals', 'Binding, Competitive', 'Citrates', 'Citric Acid', 'Enzyme Activation', 'Fructosediphosphates', 'Hexosediphosphates', 'Kinetics', 'Muscles', 'Phosphofructokinase-1', 'Rats'] | 3,159,721 | [['D03.633.100.759.646.138.180', 'D13.695.667.138.180', 'D13.695.827.068.180'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D02.241.081.901.434'], ['D02.241.081.901.434.249'], ['G02.111.263', 'G03.328'], ['D09.894.4... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association Between Acute Infectious Mononucleosis and Vitamin D Deficiency. | Epstein-Barr virus and vitamin D both have been implicated in the pathogenesis of autoimmune diseases, especially multiple sclerosis (MS). Vitamin D influences both innate and adaptive immune responses and has been linked to increased susceptibility to other viral infections such as influenza. Here we aimed to examine ... | ['Antibodies, Viral', 'Antigens, Viral', 'Capsid Proteins', 'Case-Control Studies', 'Herpesvirus 4, Human', 'Hospitals, University', 'Humans', 'Immunoglobulin M', 'Infectious Mononucleosis', 'Iran', 'Vitamin D', 'Vitamin D Deficiency'] | 27,505,106 | [['D12.776.124.486.485.114.254', 'D12.776.124.790.651.114.254', 'D12.776.377.715.548.114.254'], ['D23.050.327'], ['D12.776.964.970.600.550'], ['E05.318.372.500.500', 'N05.715.360.330.500.500', 'N06.850.520.450.500.500'], ['B04.280.210.400.500.450', 'B04.280.382.400.500.400', 'B04.613.204.500.500.400'], ['N02.278.020.30... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 |
Pathophysiological characteristics of non-alcoholic steatohepatitis-like changes in cholesterol-loaded type 2 diabetic rats. | Spontaneously Diabetic Torii (SDT) fatty rats, a new obese diabetic model, reportedly presented with features of non-alcoholic steatohepatitis (NASH) after 32 weeks of age. We tried to accelerate the onset of NASH in SDT fatty rats using dietary cholesterol loading and noticed changes in the blood choline level which i... | ['Animals', 'Cholesterol, Dietary', 'Diabetes Mellitus, Type 2', 'Female', 'Non-alcoholic Fatty Liver Disease', 'Rats', 'Rats, Sprague-Dawley'] | 29,750,881 | [['B01.050'], ['D04.210.500.247.808.197.225', 'D10.212.302.347', 'D10.570.938.208.222'], ['C18.452.394.750.149', 'C19.246.300'], ['C06.552.241.519'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A new scheme for the synthesis of 5'-nucleotide phosphonate analogs. | A convenient and general method is proposed for the synthesis of 5'-nucleotide phosphonate analogs starting from 5-deoxy-1,2-O-isopropylidene-alpha-D-xylo-hexofuranose. | ['Deoxyribonucleotides', 'Indicators and Reagents', 'Organophosphonates', 'Structure-Activity Relationship'] | 3,697,157 | [['D13.695.201'], ['D27.720.470.410'], ['D02.705.429'], ['G02.111.830', 'G07.690.773.997']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Crystallization of the alanine dehydrogenase from Phormidium lapideum. | Amino-acid dehydrogenases catalyse the interconversion of their respective amino acids to the corresponding keto acid, with concomitant reduction of NAD or NADP. The enzymes phenylalanine, glutamate, leucine and valine dehydrogenase all share a similar three-dimensional subunit structure and a high degree of sequence s... | ['Alanine Dehydrogenase', 'Algorithms', 'Amino Acid Oxidoreductases', 'Crystallization', 'Cyanobacteria', 'Escherichia coli', 'Recombinant Proteins'] | 9,761,911 | [['D08.811.682.664.500.062'], ['G17.035', 'L01.224.050'], ['D08.811.682.664.500'], ['E05.196.300', 'G02.171'], ['B03.280', 'B03.440.475.100'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D12.776.828']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Vaccination with trypomastigote surface antigen 1-encoding plasmid DNA confers protection against lethal Trypanosoma cruzi infection. | DNA vaccination was evaluated with the experimental murine model of Trypanosoma cruzi infection as a means to induce antiparasite protective immunity, and the trypomastigote surface antigen 1 (TSA-1), a target of anti-T. cruzi antibody and major histocompatibility complex (MHC) class I-restricted CD8(+) cytotoxic T-lym... | ['Animals', 'Antibodies, Protozoan', 'Antibody Specificity', 'Antigens, Protozoan', 'Antigens, Surface', 'CD8-Positive T-Lymphocytes', 'Chagas Disease', 'Female', 'Gene Expression', 'Histocompatibility Antigens Class I', 'Mice', 'Mice, Inbred BALB C', 'Mice, Inbred C3H', 'Mice, Inbred C57BL', 'Plasmids', 'T-Lymphocytes... | 9,784,506 | [['B01.050'], ['D12.776.124.486.485.114.252', 'D12.776.124.790.651.114.252', 'D12.776.377.715.548.114.252'], ['G12.100'], ['D23.050.293'], ['D23.050.301'], ['A11.118.637.555.567.569.220', 'A15.145.229.637.555.567.569.220', 'A15.382.490.555.567.569.220'], ['C01.610.752.300.900.200', 'C01.920.625'], ['G05.297'], ['D12.77... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Evidence against chronic antigen-specific T lymphocyte activation in myasthenia gravis. | Myasthenia gravis (MG) is an antigen-specific autoimmune disease caused by antibodies against acetylcholine receptors (AChR) at the post-synaptic membrane of the neuromuscular junction. Clinical and immunological data imply the involvement of AChR-specific T lymphocytes as helper cells for autoantibody production. Dire... | ['Adult', 'Aged', 'Aged, 80 and over', 'Animals', 'Antibody Specificity', 'Chronic Disease', 'Clone Cells', 'Female', 'Flow Cytometry', 'Humans', 'Lymphocyte Activation', 'Male', 'Membrane Proteins', 'Middle Aged', 'Mutation', 'Myasthenia Gravis', 'Protein Structure, Tertiary', 'Receptors, Cholinergic', 'Receptors, Int... | 8,872,911 | [['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['B01.050'], ['G12.100'], ['C23.550.291.500'], ['A11.251.353'], ['E01.370.225.500.363.342', 'E01.370.225.500.386.350', 'E05.196.712.516.600.240.350', 'E05.200.500.363.342', 'E05.200.500.386.350', 'E05.242.363.342', 'E05.242.386.350'], ['B01.050.150.900.649... | ['Named Groups [M]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Identification of immunoglobulin superfamily 11 (IGSF11) as a novel target for cancer immunotherapy of gastrointestinal and hepatocellular carcinomas. | We previously performed gene expression profile analyses of 20 intestinal-type gastric cancers, and identified a set of genes whose expression levels were elevated in cancer tissues compared to their corresponding non-cancerous tissues. In the present study we focused on the immunoglobulin superfamily 11 gene (IGSF11).... | ['3T3 Cells', 'Animals', 'Carcinoma, Hepatocellular', 'Cell Adhesion Molecules', 'Cell Division', 'Cell Line, Tumor', 'Colonic Neoplasms', 'Gastrointestinal Neoplasms', 'Glycoproteins', 'Humans', 'Immunoglobulins', 'Immunotherapy', 'Liver Neoplasms', 'Male', 'Mice', 'Protein Isoforms', 'Reverse Transcriptase Polymerase... | 16,108,831 | [['A11.251.210.100', 'A11.329.228.100'], ['B01.050'], ['C04.557.470.200.025.255', 'C04.588.274.623.160', 'C06.301.623.160', 'C06.552.697.160'], ['D12.776.395.550.200', 'D12.776.543.550.200', 'D23.050.301.350'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210.190', 'A11.251.860.18... | ['Anatomy [A]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pentachlorophenol treatment in vivo elevates point mutation rate in zebrafish p53 gene. | Pentachlorophenol (PCP), a probable human carcinogen, has been heavily used as an aseptic and a biocide throughout the world, and is widely present in the environment. Recent survey in Germany revealed that the average PCP amount in the urine of general German populations was 1.04 microg/L while the peak concentration ... | ['Animals', 'Base Sequence', 'Chromatography, High Pressure Liquid', 'DNA', 'DNA Mutational Analysis', 'Dose-Response Relationship, Drug', 'Fish Proteins', 'Insecticides', 'Liver', 'Molecular Sequence Data', 'Pentachlorophenol', 'Point Mutation', 'Polymorphism, Single Nucleotide', 'Toxicity Tests, Acute', 'Transition T... | 16,904,934 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['E05.196.181.400.300'], ['D13.444.308'], ['E05.393.760.700.300'], ['G07.690.773.875', 'G07.690.936.500'], ['D12.776.325'], ['D27.720.031.700.491', 'D27.888.723.491'], ['A03.620'], ['L01.453.245.667'], ['D02.455.426.559.389.657.190.633'], ['G05.36... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Development of sexual orientation among adolescent and young adult women. | Although some research suggests that sexual orientation is a stable, early appearing trait, interviews with 89 young sexual-minority women revealed that a majority of women failed to report at least one of the following: childhood indicators of sexual orientation, stability in same-sex attractions, or awareness of same... | ['Adolescent', 'Adult', 'Bisexuality', 'Child', 'Female', 'Gender Identity', 'Homosexuality, Female', 'Humans', 'Psychosexual Development', 'Sexual Behavior'] | 9,779,753 | [['M01.060.057'], ['M01.060.116'], ['F01.145.802.975.200', 'G08.686.867.200'], ['M01.060.406'], ['F01.393.446.250', 'F01.752.747.385.200', 'F01.752.747.722.200', 'F02.739.794.793.200'], ['F01.145.802.975.500.400', 'G08.686.867.500.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F01.752.747.722', 'F02.739.794.... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Nasal malignant granular cell tumor: a case report]. | We reported a case of nasal malignant granular cell tumor. The patient was a 51 years old man who went to the hospital because of "right nasal intermittent bleeding for half a year". The pathological examination after resection showed malignant granular cell tumor. No recurrence was noted during a year after resection.... | ['Epistaxis', 'Granular Cell Tumor', 'Humans', 'Male', 'Middle Aged', 'Neoplasm Recurrence, Local', 'Nose', 'Nose Neoplasms'] | 26,103,675 | [['C08.460.261', 'C09.603.261', 'C23.550.414.712', 'C23.888.852.040'], ['C04.557.450.590.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C04.697.655', 'C23.550.727.655'], ['A01.456.505.733', 'A04.531', 'A09.531'], ['C04.588.149.721.600', 'C04.588.443.665.650', 'C05.116.231.754.600', 'C08.... | ['Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.