Title stringlengths 1 395 ⌀ | abstractText stringlengths 57 5.98k | meshMajor stringlengths 14 1.03k | pmid int64 22 33.2M | meshid stringlengths 2 3.14k | meshroot stringlengths 2 421 | A int64 0 1 | B int64 0 1 | C int64 0 1 | D int64 0 1 | E int64 0 1 | F int64 0 1 | G int64 0 1 | H int64 0 1 | I int64 0 1 | J int64 0 1 | L int64 0 1 | M int64 0 1 | N int64 0 1 | Z int64 0 1 |
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Respiration paralysing and circulatory effects of a new non-depolarizing relaxant, pipecurium bromide, in anaesthetized dogs. | The effect of a new sterane-structure, non-depolarizing muscle relaxant 2 beta,16 beta-bis(4'-dimethyl-1'-piperazino)-3 alpha,17 beta-diacetoxy-5 alpha-androstane dibromide (pipecurium bromide, RGH-1106, Arduan) was studied in 42 mongrel dogs under general anaesthesia (ether, halothane, methoxyflurane, thiobutobarbital... | ['Androstane-3,17-diol', 'Androstanols', 'Anesthesia', 'Animals', 'Blood Pressure', 'Dogs', 'Drug Interactions', 'Electrocardiography', 'Female', 'Heart Rate', 'Hemodynamics', 'Male', 'Neuromuscular Blocking Agents', 'Pipecuronium', 'Piperazines', 'Respiration', 'Time Factors'] | 6,248,078 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Investigating gender disparities in the profile and treatment outcomes of tuberculosis in Ebonyi state, Nigeria. | SUMMARY Globally, twice as many men as women are being diagnosed with tuberculosis (TB) annually. Little is known about gender differentials in TB in Africa. A retrospective cohort analysis of routine data was conducted on adult TB patients treated between 2011 and 2012 in two large healthcare facilities in Nigeria. Ge... | ['Adult', 'Antitubercular Agents', 'Cohort Studies', 'Coinfection', 'Ethambutol', 'Female', 'HIV Infections', 'Health Status Disparities', 'Humans', 'Isoniazid', 'Male', 'Middle Aged', 'Nigeria', 'Pyrazinamide', 'Retrospective Studies', 'Rifampin', 'Rural Population', 'Sex Factors', 'Streptomycin', 'Time Factors', 'Tre... | 25,355,040 | [['M01.060.116'], ['D27.505.954.122.085.255'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C01.218'], ['D02.092.782.258.368.265'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['I01.240.425.675', 'N01.224... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Dose effect on intramuscular metabolic stress during low-intensity resistance exercise with blood flow restriction. | Our previous study reported that metabolic stress in skeletal muscle achieved by combining moderate blood flow restriction (BFR) with low-intensity resistance exercise at 20% of one repetition maximum (1 RM) could not reach the level achieved by high-intensity resistance exercise. Since the previous protocol is typical... | ['Adenosine Triphosphate', 'Blood Flow Velocity', 'Energy Metabolism', 'Female', 'Humans', 'Male', 'Physical Exertion', 'Physical Fitness', 'Resistance Training', 'Stress, Physiological', 'Young Adult'] | 20,360,434 | [['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['E01.370.370.130', 'G09.330.380.630.080'], ['G03.295'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.683'], ['G11.427.685', 'I03.450.642.845.054.800', 'N01.400.545'], ['E02.760.169.063.500.387.875', 'E02.779.483.875', 'E02.83... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Named Groups [M]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 |
High antigen density and IL-2 are required for generation of CD4 effectors secreting Th1 rather than Th0 cytokines. | We reevaluated the effects of Ag dose on the polarization of CD4 effectors generated in vitro from naive pigeon cytochrome c-specific TCR transgenic T cells under conditions in which we could eliminate contaminating non-naive CD4 cells and the effects of heterogeneous Ag-presenting populations. When the possibility of ... | ['Animals', 'Antigen Presentation', 'CD4 Antigens', 'Cell Differentiation', 'Immunity, Cellular', 'Lymphocyte Activation', 'Mice', 'Mice, Transgenic', 'T-Lymphocyte Subsets', 'Th1 Cells', 'Th2 Cells'] | 9,780,149 | [['B01.050'], ['G12.119', 'G12.450.050.400.070'], ['D12.776.543.750.705.852.420.810.500', 'D12.776.543.750.830.700.025', 'D23.050.301.264.894.100', 'D23.101.100.894.100'], ['G04.152'], ['G12.450.050.400'], ['E01.370.225.812.482', 'E05.200.812.482', 'E05.478.594.530', 'G12.450.050.400.545', 'G12.565'], ['B01.050.150.900... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Corrected placement of Mus-Rattus fossil calibration forces precision in the molecular tree of rodents. | Time calibration derived from the fossil record is essential for molecular phylogenetic and evolutionary studies. Fossil mice and rats, discovered in the Siwalik Group of Pakistan, have served as one of the best-known fossil calibration points in molecular phylogenic studies. Although these fossils have been widely use... | ['Animals', 'Evolution, Molecular', 'Fossils', 'Mice', 'Paleontology', 'Phylogeny', 'Rats', 'Rodentia'] | 26,411,391 | [['B01.050'], ['G05.045.250', 'G16.075.250'], ['I01.076.368.584.311'], ['B01.050.150.900.649.313.992.635.505.500'], ['H01.277.875', 'I01.076.368.584'], ['G05.697', 'G16.075.605', 'L01.100.697'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Disciplines and Occupations [H]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 |
Protection of pregnant swine by vaccination against Leptospira infection. | The protection conferred on pregnant gilts by 2 commercially available leptospira interrogans serovars pomona and tarassovi bacterins was evaluated. Gilts vaccinated either 3, 6 or 12 months prior to natural challenge with L. interrogans serovar pomona had significantly lower abortion rates (2% vs 69%) and foetal morta... | ['Animals', 'Antibodies, Bacterial', 'Bacterial Vaccines', 'Female', 'Leptospira interrogans', 'Pregnancy', 'Pregnancy Complications, Infectious', 'Swine', 'Swine Diseases', 'Vaccination', 'Weil Disease'] | 7,150,130 | [['B01.050'], ['D12.776.124.486.485.114.107', 'D12.776.124.790.651.114.125', 'D12.776.377.715.548.114.125'], ['D20.215.894.135'], ['B03.440.400.425.475.475.400', 'B03.851.475.475.400'], ['G08.686.784.769'], ['C01.674', 'C13.703.700'], ['B01.050.150.900.649.313.500.880'], ['C22.905'], ['E02.095.465.425.400.530.890', 'E0... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Outcome of Encephalitis in Pediatric Intensive Care Unit. | OBJECTIVE: To review pathogens, morbidity and mortality in pediatric intensive care unit (PICU) patients with viral and infectious encephalitis.METHODS: Retrospective chart review of all patients with encephalitis admitted to the PICU between 2002 and 2014 was done.RESULTS: Encephalitis (n = 46) accounted for 2.7 % of ... | ['Child', 'Encephalitis', 'Female', 'Hospitalization', 'Humans', 'Infant', 'Intensive Care Units, Pediatric', 'Male', 'Prognosis', 'Respiratory Syncytial Viruses', 'Retrospective Studies'] | 27,053,179 | [['M01.060.406'], ['C10.228.140.430'], ['E02.760.400', 'N02.421.585.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['N02.278.388.493.390'], ['E01.789'], ['B04.820.480.937.600.670.600.750'], ['E05.318.372.500.500.500', 'E05.318.372.500.750.750', 'N05.715.360.330.500.500.500', 'N05.715.360.330.5... | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Microvascular thermal equilibration in rat spinotrapezius muscle. | The current study investigates heat exchange in the thermally significant countercurrent paired vessels of the rat spinotrapezius muscle. Detailed tissue surface temperatures under normal (after the microvascular surgery) and pharmacologically vasodilated states were measured using high-resolution infrared thermography... | ['Animals', 'Body Temperature Regulation', 'Male', 'Microcirculation', 'Muscle, Skeletal', 'Rats', 'Rats, Sprague-Dawley', 'Thermal Conductivity'] | 9,916,761 | [['B01.050'], ['G07.110.232', 'G07.410.421', 'G16.012.500.535'], ['G09.330.100.645'], ['A02.633.567', 'A10.690.552.500'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.750'], ['G01.906.730']] | ['Organisms [B]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Determination of carbazochrome by fluorescence quenching method. | A sensitive, simple and selective spectrofluorimetric method for the reaction of carbazochrome (CBZC) and Eosin Y (EY) or Phloxine B (PB) in acidic medium is developed for the determination of carbazochrome in biological fluids, which gives a highly fluorescent derivative measured at 545 and 565 nm at excitation wavele... | ['Adrenochrome', 'Eosine I Bluish', 'Eosine Yellowish-(YS)', 'Fluorescence', 'Humans', 'Hydrogen-Ion Concentration', 'Kinetics', 'Limit of Detection', 'Spectrometry, Fluorescence', 'Temperature', 'Time Factors'] | 22,750,685 | [['D03.633.100.473.025', 'D23.767.061'], ['D02.455.426.779.347.300', 'D03.633.300.953.275.300', 'D04.711.347.300'], ['D02.455.426.779.347.325', 'D03.633.300.953.275.325', 'D04.711.347.325'], ['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.300'], ['G01.374.6... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A severe frontal-parietal lobe syndrome following cerebellar damage. | We report a case study of a frontal and parietal lobe syndrome with memory loss after unilateral left-sided cerebellar damage caused by a stroke in a patient with right cerebellar unusual developmental agenesis. The syndrome consisted of severe deficits in planning an organized sequence of events, in visuo-constructive... | ['Adult', 'Attention', 'Cerebellar Diseases', 'Frontal Lobe', 'Humans', 'Male', 'Mental Processes', 'Parietal Lobe', 'Personality', 'Stroke', 'Tomography, Emission-Computed, Single-Photon', 'Tomography, X-Ray Computed'] | 11,422,432 | [['M01.060.116'], ['F02.830.104.214'], ['C10.228.140.252'], ['A08.186.211.200.885.287.500.270'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['F02.463'], ['A08.186.211.200.885.287.500.670'], ['F01.752'], ['C10.228.140.300.775', 'C14.907.253.855'], ['E01.370.350.350.800.800', 'E01.370.350.600.350.800.800', 'E01.370... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Measures for improving therapeutic results of esophageal carcinoma in stage III: preoperative radiotherapy. | Surgical therapeutic results of esophageal carcinoma stage III in 245 cases admitted to our hospital from 1966 to 1982 are reported in this paper. In this series, 171 cases were treated by surgery alone and 74 cases treated with a combination of preoperative radiotherapy and surgery. Of the entire group, 184 cases unde... | ['Adenocarcinoma', 'Adult', 'Aged', 'Carcinoma, Squamous Cell', 'Combined Modality Therapy', 'Esophageal Neoplasms', 'Esophagoplasty', 'Female', 'Humans', 'Male', 'Middle Aged', 'Postoperative Complications', 'Preoperative Care', 'Prognosis'] | 3,736,069 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['C04.557.470.200.400', 'C04.557.470.700.400'], ['E02.186'], ['C04.588.274.476.205', 'C04.588.443.353', 'C06.301.371.205', 'C06.405.117.430', 'C06.405.249.205'], ['E04.210.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C23.5... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Electric field modulation of magnetic exchange in molecular helices. | The possibility to operate on magnetic materials through the application of electric rather than magnetic fields-promising faster, more compact and energy efficient circuits-continues to spur the investigation of magnetoelectric effects. Symmetry considerations, in particular the lack of an inversion centre, characteri... | ['Electricity', 'Magnetic Fields', 'Manganese', 'Models, Molecular', 'Molecular Conformation', 'Organometallic Compounds'] | 30,778,229 | [['G01.358.500.249'], ['G01.358.750'], ['D01.268.556.484', 'D01.268.956.374', 'D01.552.544.484'], ['E05.599.595'], ['G02.111.570.820'], ['D02.691']] | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
The glyceraldehyde-3-phosphate dehydrogenase of Clostridium acetobutylicum: isolation and purification of the enzyme, and sequencing and localization of the gap gene within a cluster of other glycolytic genes. | Glyceraldehyde-3-phosphate dehydrogenase was purified from Clostridium acetobutylicum by sequential ammonium sulfate precipitation, gel filtration and anion-exchange chromatography (to a specific activity of 27 U mg-1). The enzyme had a molecular mass of 40 kDa as determined by SDS-PAGE and a native molecular mass of 1... | ['Cloning, Molecular', 'Clostridium', 'Electrophoresis, Polyacrylamide Gel', 'Escherichia coli', 'Genes, Bacterial', 'Genetic Complementation Test', 'Glyceraldehyde-3-Phosphate Dehydrogenases', 'Glycolysis', 'Molecular Sequence Data', 'Multigene Family', 'Nucleic Acid Hybridization', 'Polymerase Chain Reaction', 'Seque... | 10,463,150 | [['E05.393.220'], ['B03.300.390.400.200', 'B03.353.625.375.500', 'B03.510.415.400.200'], ['E05.196.401.402', 'E05.301.300.319'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G05.360.340.024.340.364.249', 'G05.360.340.358.024.249', 'G05.360.340.358.207.249'], ['E05.393.281.526'], ['D08.811.682.657.163.750']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Information Science [L]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
The effect of dioptric blur on reading performance. | Little is known about the systematic impact of blur on reading performance. The purpose of this study was to quantify the effect of dioptric blur on reading performance in a group of normally sighted young adults. We measured monocular reading performance and visual acuity for 19 observers with normal vision, for five ... | ['Adult', 'Astigmatism', 'Form Perception', 'Humans', 'Mydriatics', 'Reading', 'Sensory Thresholds', 'Tropicamide', 'Vision Tests', 'Visual Acuity'] | 17,442,363 | [['M01.060.116'], ['C11.744.212'], ['F02.463.593.373', 'F02.463.593.778.435'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D27.505.696.663.050.500'], ['L01.559.423.557'], ['F02.463.593.710'], ['D03.383.725.942'], ['E01.370.380.850'], ['E01.370.380.850.950', 'F02.463.593.932.901', 'G14.940']] | ['Named Groups [M]', 'Diseases [C]', 'Psychiatry and Psychology [F]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
Sclerocornea associated with the Smith-Lemli-Opitz syndrome. | A 2,000-g infant boy had many features of the Smith-Lemli-Opitz syndrome (prenatal growth deficiency and developmental retardation, microcephaly with unusual facies, hypospadias, and feeding difficulties) as well as sclerocornea. The association of this rare eye finding with this rare congenital syndrome is unique. Suc... | ['Abnormalities, Multiple', 'Cornea', 'Corneal Diseases', 'Growth Disorders', 'Humans', 'Infant', 'Male', 'Microcephaly', 'Sclera', 'Syndrome'] | 900,220 | [['C16.131.077'], ['A09.371.060.217'], ['C11.204'], ['C23.550.393'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['C05.660.207.620', 'C10.500.507.400.500', 'C16.131.621.207.620', 'C16.131.666.507.400.500'], ['A09.371.784'], ['C23.550.288.500']] | ['Diseases [C]', 'Anatomy [A]', 'Organisms [B]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Generating prior probabilities for classifiers of brain tumours using belief networks. | BACKGROUND: Numerous methods for classifying brain tumours based on magnetic resonance spectra and imaging have been presented in the last 15 years. Generally, these methods use supervised machine learning to develop a classifier from a database of cases for which the diagnosis is already known. However, little has bee... | ['Bayes Theorem', 'Brain Neoplasms', 'Child', 'Databases, Factual', 'Decision Support Techniques', 'Diagnosis, Computer-Assisted', 'Diagnosis, Differential', 'Germinoma', 'Humans', 'Magnetic Resonance Spectroscopy', 'Neoplasm Staging', 'Neuroectodermal Tumors', 'Probability'] | 17,877,822 | [['E05.318.740.600.200', 'N05.715.360.750.625.150', 'N06.850.520.830.600.200'], ['C04.588.614.250.195', 'C10.228.140.211', 'C10.551.240.250'], ['M01.060.406'], ['L01.313.500.750.300.188.400', 'L01.470.750.750'], ['E05.245', 'L01.313.500.750.190'], ['E01.158', 'L01.313.500.750.100.158'], ['E01.171'], ['C04.557.465.330']... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Named Groups [M]', 'Information Science [L]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Localization of the phalloidin and nucleotide-binding sites on actin. | Phalloidin was found to block nucleotide exchange in F-actin, without interfering with nucleotide hydrolysis. This inhibition of nucleotide exchange occurs under conditions in which monomers are able to exchange. The distance separating a fluorescent chromophore attached to phalloidin from the nucleotide on actin was d... | ['Actins', 'Adenosine Diphosphate', 'Adenosine Triphosphate', 'Allosteric Regulation', 'Binding Sites', 'Energy Transfer', 'Magnetic Resonance Spectroscopy', 'Nucleotides', 'Oligopeptides', 'Peptide Fragments', 'Phalloidine', 'Spectrometry, Fluorescence'] | 3,830,158 | [['D05.750.078.730.250', 'D12.776.210.500.100', 'D12.776.220.525.255'], ['D03.633.100.759.646.138.124', 'D13.695.667.138.124', 'D13.695.827.068.124'], ['D03.633.100.759.646.138.236', 'D13.695.667.138.236', 'D13.695.827.068.236'], ['G02.111.044'], ['G02.111.570.120'], ['G01.154.240', 'G02.111.255', 'G02.216'], ['E05.196... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Infrared digital thermography of scrotum in early selection of progressive varicocele. | Varicocele is frequent but correctable cause of male infertility. Varicocelectomy is the most commonly performed operative procedure for varicocele. Majority of varicocele patients do not have fertility problem, therefore surgical correction is not recommended in all prevalent cases. On the other hand, varicocele is a ... | ['Humans', 'Infrared Rays', 'Male', 'Scrotum', 'Skin Temperature', 'Thermography', 'Varicocele'] | 23,891,041 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['G01.358.500.505.650.552', 'G01.590.540.552', 'G01.750.250.650.552', 'G01.750.770.578.552', 'G16.500.275.063.725.525.400', 'G16.500.750.775.525.400', 'N06.230.300.100.725.525.400'], ['A05.360.444.661'], ['G07.110.753', 'G13.750.844'], ['E01.370.350.800', 'E05.933.500']... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
A Novel Mathematical Model for Determining Faculty Workload. | Objective. To develop a mathematical model for determining faculty workload at a college of pharmacy with a team-based learning curriculum. Methods. Using faculty provided data, our model calculated activity and weighted means in teaching, scholarship and service. Subsequently, these data were used to develop departmen... | ['Education, Pharmacy', 'Faculty, Pharmacy', 'Models, Theoretical', 'Research', 'Schools, Pharmacy', 'Teaching', 'Workforce', 'Workload'] | 28,090,101 | [['I02.358.525'], ['M01.526.702.250.736'], ['E05.599'], ['H01.770.644'], ['I02.783.495.694'], ['I02.903'], ['N04.452.525'], ['I03.946.225.500', 'N04.452.677.650.500']] | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 0 |
Informed consent and clinical research involving children and adolescents: implications of the revised APA ethics code and HIPAA. | In 2003, 2 new sets of rules and regulations affecting the conduct of clinical research involving children and adolescents went into effect: the revised American Psychological Association's (APA) Ethical Principles of Psychologists and Code of Conduct (APA, 2002; effective June 1, 2003) and the Privacy Rule (45 CFR Par... | ['Adolescent', 'Biomedical Research', 'Child', 'Child Advocacy', 'Codes of Ethics', 'Health Insurance Portability and Accountability Act', 'Human Experimentation', 'Humans', 'Informed Consent', 'Privacy', 'Psychology, Clinical', 'Societies, Medical', 'United States'] | 15,498,750 | [['M01.060.057'], ['H01.770.644.145'], ['M01.060.406'], ['I01.880.604.473.300', 'I01.880.787.293.350', 'N03.706.437.300'], ['K01.752.566.479.068', 'K01.752.566.479.171.066', 'N04.761.700.350.324', 'N05.350.213', 'N05.350.340.080', 'N05.700.350.324'], ['N03.219.521.576.343.349', 'N03.706.615.273'], ['E05.445', 'H01.770.... | ['Named Groups [M]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Humanities [K]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Psychiatry and Psychology [F]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 1 |
Computed tomography-guided transsphenoidal closure of postsurgical cerebrospinal fluid fistula: a transmucosal needle technique. | BACKGROUND: Cerebrospinal fluid (CSF) fistula represents a fearful complication of transsphenoidal surgery and, despite careful intraoperative repair and prolonged postoperative lumbar CSF drainage, need for a new surgical intrasphenoidal plasty is not uncommon.METHODS: These cases prompted us to develop a simple, mini... | ['Adult', 'Cerebrospinal Fluid Rhinorrhea', 'Female', 'Fibrin Tissue Adhesive', 'Fistula', 'Follow-Up Studies', 'Humans', 'Male', 'Middle Aged', 'Needles', 'Postoperative Complications', 'Tomography, X-Ray Computed'] | 9,315,142 | [['M01.060.116'], ['C10.597.114.750', 'C10.900.300.109.750', 'C23.888.592.114.624', 'C23.888.852.834.500', 'C26.915.300.225.750'], ['D12.776.124.270.305'], ['C23.300.575'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.0... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Neuromodulation of guinea pig intestinal electrolyte transport by cholecystokinin octapeptide. | We examined the effect of cholecystokinin octapeptide on electrolyte transport across isolated guinea pig mucosa. Segments of distal ileum stripped of longitudinal muscle and bathed on both sides with a Krebs'-bicarbonate buffer responded to cholecystokinin octapeptide when studied under short-circuited conditions. Cho... | ['Animals', 'Atropine', 'Biological Transport', 'Bumetanide', 'Calcium', 'Culture Media', 'Dose-Response Relationship, Drug', 'Electrolytes', 'Electrophysiology', 'Guinea Pigs', 'Ileum', 'Intestinal Mucosa', 'Intestines', 'Male', 'Proglumide', 'Receptors, Cholecystokinin', 'Sincalide', 'Tetrodotoxin'] | 1,985,032 | [['B01.050'], ['D02.145.074.722.229.199', 'D03.132.760.180.572.199', 'D03.132.889.180.648.199', 'D03.605.084.500.722.229.199', 'D03.605.869.229.199'], ['G03.143'], ['D02.065.884.150', 'D02.241.223.100.050.300.200', 'D02.455.426.559.389.127.020.452.500', 'D02.886.590.700.150'], ['D01.268.552.100', 'D01.552.539.288', 'D2... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Anatomy [A]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Phospholipid composition and surface-active properties of tracheobronchial secretions from patients with cystic fibrosis and chronic obstructive pulmonary diseases. | Among the various components of tracheobronchial secretions, lipids and particularly phospholipids have been shown to influence rheological properties of airway secretions in patients with cystic fibrosis. We studied the phospholipid composition of tracheobronchial secretions, collected from patients suffering from cys... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Bronchiectasis', 'Child', 'Cystic Fibrosis', 'Humans', 'Lung Diseases, Obstructive', 'Middle Aged', 'Mucus', 'Phospholipids', 'Surface Properties'] | 1,589,308 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C08.127.384'], ['M01.060.406'], ['C06.689.202', 'C08.381.187', 'C16.320.190', 'C16.614.213'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C08.381.495'], ['M01.060.116.630'], ['A12.200.503'], ['D10.570.755'], ['G02.860']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Incident cases of heart failure in a community cohort: importance and outcomes of patients with preserved systolic function. | BACKGROUND: The clinical presentation and outcomes of patients with heart failure and preserved systolic function have not been well characterized in the outpatient setting.METHODS: This was a retrospective cohort study of 403 patients with new-onset heart failure in a large regional health maintenance organization bet... | ['Aged', 'Cohort Studies', 'Female', 'Heart Failure', 'Humans', 'Male', 'Proportional Hazards Models', 'Retrospective Studies', 'Systole', 'Ventricular Dysfunction, Left', 'Ventricular Function, Left'] | 12,851,618 | [['M01.060.116.100'], ['E05.318.372.500.750', 'N05.715.360.330.500.750', 'N06.850.520.450.500.750'], ['C14.280.434'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E05.318.740.500.700', 'E05.318.740.600.700', 'E05.318.740.750.725', 'E05.318.740.998.825', 'E05.599.835.900', 'N05.715.360.750.530.650', 'N05.715.360.7... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Sublingual piroxicam for postoperative analgesia: preoperative versus postoperative administration: a randomized, double-blind study. | Nonsteroidal antiinflammatory drugs have been used to obtain preemptive analgesia. We investigated, in this randomized, double-blind study, whether sublingual (s.l.) piroxicam given before was more effective than that given after surgery. Fifty-two patients scheduled for laparoscopic bilateral inguinal hernia repair un... | ['Administration, Sublingual', 'Adolescent', 'Adult', 'Analgesia', 'Double-Blind Method', 'Female', 'Humans', 'Male', 'Pain Measurement', 'Pain, Postoperative', 'Piroxicam', 'Postoperative Care', 'Preoperative Care', 'Prospective Studies'] | 16,492,824 | [['E02.319.267.100.878'], ['M01.060.057'], ['M01.060.116'], ['E03.091'], ['E05.318.370.300', 'E05.581.500.300', 'N05.715.360.325.320', 'N06.850.520.445.300'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.600.550.324'], ['C23.550.767.700', 'C23.888.592.612.832'], ['D02.886.665.500', 'D03.383.855.500'], ['E... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Named Groups [M]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Changes in CD4 lymphocyte counts after interruption of therapy in patients with viral failure on protease inhibitor-containing regimens. Royal Free Centre for HIV Medicine. | OBJECTIVE: To describe the short-term changes in CD4 lymphocyte counts after the interruption of antiretroviral HIV therapy in order to increase the understanding of CD4 lymphocyte dynamics, and so that appropriate monitoring strategies can be designed.METHODS: We studied 35 HIV-infected patients with late-stage diseas... | ['Adult', 'Anti-HIV Agents', 'CD4 Lymphocyte Count', 'Female', 'HIV', 'HIV Infections', 'HIV Protease Inhibitors', 'Humans', 'Male', 'RNA, Viral', 'Time Factors', 'Viral Load'] | 10,985,307 | [['M01.060.116'], ['D27.505.954.122.388.077.088'], ['E01.370.225.500.195.107.595.500.150', 'E01.370.225.625.107.595.500.150', 'E05.200.500.195.107.595.500.150', 'E05.200.625.107.595.500.150', 'E05.242.195.107.595.500.150', 'G04.140.107.595.500.150', 'G09.188.105.595.500.150'], ['B04.820.650.589.650.350'], ['C01.221.250... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Experimental study of bone lengthening in dogs by means of backscattered scanning electron microscopy. | OBJECTIVE: To describe the morphology of calcified tissues involved in distraction osteogenesis (DO) by means of backscattered scanning electron microscopy (BS-SEM).STUDY DESIGN: Experimental study.ANIMALS: Adult female Beagle dogs (n=12).METHODS: Non-simultaneous and bilateral transverse mid-diaphyseal osteotomies per... | ['Animals', 'Autopsy', 'Bone Nails', 'Calcification, Physiologic', 'Dogs', 'External Fixators', 'Female', 'Microscopy, Electron, Scanning', 'Osteogenesis, Distraction', 'Osteotomy', 'Radiography', 'Tibia'] | 19,573,104 | [['B01.050'], ['E01.370.060', 'E05.070', 'I01.198.780.937.120'], ['E07.695.370.249', 'E07.858.442.660.460.249', 'E07.858.690.725.460.249'], ['G07.345.155.500', 'G07.345.500.325.377.625.050.500.175', 'G11.427.578.050.500.175'], ['B01.050.150.900.649.313.750.250.216.200'], ['E07.858.442.660.430', 'E07.858.690.725.430'], ... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Effects of gel volume on pharmacokinetics for vaginal and rectal applications of combination DuoGel-IQB4012, a dual chamber-dual drug HIV microbicide gel, in pigtailed macaques. | This study evaluated effects of differing gel volumes on pharmacokinetics (PK). IQB4012, a gel containing the non-nucleoside reverse transcriptase inhibitor IQP-0528 and tenofovir (TFV), was applied to the pigtailed macaque vagina and rectum. Vaginal gel volumes (1% loading of both drugs) were 0.5 or 1.5 ml; following ... | ['Administration, Rectal', 'Animals', 'Anti-HIV Agents', 'Female', 'Macaca', 'Pyrimidinones', 'Tenofovir', 'Vaginal Creams, Foams, and Jellies'] | 29,761,350 | [['E02.319.267.120.655.750'], ['B01.050'], ['D27.505.954.122.388.077.088'], ['B01.050.150.900.649.313.988.400.112.199.120.510'], ['D03.383.742.698'], ['D02.705.429.906', 'D03.633.100.759.138.881'], ['D26.255.955', 'E07.357.750']] | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Prevalence and factors influencing the distribution of influenza viruses in Kenya: Seven-year hospital-based surveillance of influenza-like illness (2007-2013). | BACKGROUND: Influenza viruses remain a global threat with the potential to trigger outbreaks and pandemics. Globally, seasonal influenza viruses' mortality range from 291 243-645 832 annually, of which 17% occurs in Sub-Saharan Africa. We sought to estimate the overall prevalence of influenza infections in Kenya, ident... | ['Adolescent', 'Adult', 'Aged', 'Child', 'Child, Preschool', 'Demography', 'Epidemiological Monitoring', 'Female', 'Humans', 'Infant', 'Influenza A Virus, H1N1 Subtype', 'Influenza A Virus, H3N2 Subtype', 'Influenza B virus', 'Influenza, Human', 'Kenya', 'Male', 'Middle Aged', 'Nasopharynx', 'Prevalence'] | 32,822,390 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.406'], ['M01.060.406.448'], ['I01.240', 'N01.224', 'N06.850.505.400'], ['E05.318.375', 'N06.850.520.460'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['B04.820.480.968.405.400.214'], ['B04.820.480.968.405.400.300'], ['B04.820.480.9... | ['Named Groups [M]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Geographicals [Z]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Carboxypeptidase M is a positive allosteric modulator of the kinin B1 receptor. | Ligand binding to extracellular domains of G protein-coupled receptors can result in novel and nuanced allosteric effects on receptor signaling. We previously showed that the protein-protein interaction of carboxypeptidase M (CPM) and kinin B1 receptor (B1R) enhances B1R signaling in two ways; 1) kinin binding to CPM c... | ['Allosteric Regulation', 'GPI-Linked Proteins', 'HEK293 Cells', 'Humans', 'MAP Kinase Signaling System', 'Metalloendopeptidases', 'Mitogen-Activated Protein Kinase 1', 'Mitogen-Activated Protein Kinase 3', 'Protein Structure, Secondary', 'Protein Structure, Tertiary', 'Receptor, Bradykinin B1'] | 24,108,126 | [['G02.111.044'], ['D12.776.395.550.448', 'D12.776.543.484.500', 'D12.776.543.550.418'], ['A11.251.210.172.750', 'A11.436.334'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.820.560', 'G03.493.560', 'G04.835.560'], ['D08.811.277.656.300.480', 'D08.811.277.656.675.374'], ['D08.811.913.696.620.682.700.567.2... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hypertension in autosomal dominant polycystic kidney disease: observational study in 207 patients with a mean follow-up of 107 months. | INTRODUCTION AND OBJECTIVES: Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common hereditary diseases in adults. ADPKD is a frequent cause of 4 secondary hypertension and, conversely, hypertension is a common manifestation of ADPKD and, more importantly, one of the few that are treatable. Give... | ['Adult', 'Follow-Up Studies', 'Humans', 'Hypertension', 'Polycystic Kidney, Autosomal Dominant', 'Retrospective Studies', 'Time Factors'] | 18,297,839 | [['M01.060.116'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['C12.777.419.403.875.500', 'C13.351.968.419.403.875.500', 'C16.131.077.717.500', 'C16.320.184.625.500'], ['E05.318.372.500.500.500', 'E05.318.37... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Intrapleural Antimicrobial Irrigation for Postpneumonectomy Empyema in Patients With Lung Cancer. | PURPOSE: Postpneumonectomy empyema (PPE) is a possible complication after a pneumonectomy in patients with lung cancer. The use of intrapleural (IP) antibiotic irrigation to treat infections in the pleural space may be indicated after systemic antimicrobial therapy, and drainage of the pleural space has been insufficie... | ['Aged', 'Anti-Infective Agents', 'Empyema, Pleural', 'Female', 'Humans', 'Lung Neoplasms', 'Male', 'Middle Aged', 'Pneumonectomy', 'Postoperative Complications', 'Retrospective Studies', 'Therapeutic Irrigation'] | 25,107,425 | [['M01.060.116.100'], ['D27.505.954.122'], ['C01.748.265', 'C01.830.305.310', 'C08.528.240', 'C08.730.265', 'C23.550.470.756.305.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.588.894.797.520', 'C08.381.540', 'C08.785.520'], ['M01.060.116.630'], ['E04.620', 'E04.928.600.600'], ['C23.550.767'], ['E05.318.... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
The Importance of Demodex Mites (Acari: Demodicidae) in Patients With Sickle Cell Anemia. | Although demodicosis caused by Demodex folliculorum and Demodex brevis is widely seen throughout the world, the pathogenic mechanisms are not fully known. To the best of our knowledge, the effect of Demodex mites in patients with sickle cell anemia (SCA) is not known. SCA is a genetic disease characterized by abnormal ... | ['Adult', 'Anemia, Sickle Cell', 'Animals', 'Female', 'Humans', 'Male', 'Middle Aged', 'Mite Infestations', 'Mites', 'Prevalence', 'Skin', 'Turkey', 'Young Adult'] | 30,576,478 | [['M01.060.116'], ['C15.378.071.141.150.150', 'C15.378.420.155', 'C16.320.070.150', 'C16.320.365.155'], ['B01.050'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['C01.610.858.211.480'], ['B01.050.500.131.166.132.419'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525... | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Anatomy [A]', 'Geographicals [Z]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Alkyl radicals as hydrogen bond acceptors: computational evidence. | Spectroscopic, energetic and structural information obtained by DFT and G3-type computational studies demonstrates that charged proton donors can form moderately strong hydrogen bonds to simple alkyl radicals. The presence of these bonds stabilizes the adducts and modifies their structure, and gives rise to pronounced ... | ['Alkanes', 'Free Radicals', 'Hydrogen Bonding', 'Models, Chemical', 'Spectrophotometry, Infrared', 'Static Electricity', 'Thermodynamics', 'Water'] | 19,489,573 | [['D02.455.326.146'], ['D01.339', 'D02.389'], ['G02.282'], ['E05.599.495'], ['E05.196.712.726.676', 'E05.196.867.826.676'], ['G01.358.500.249.820'], ['G01.906'], ['D01.045.250.875', 'D01.248.497.158.459.650', 'D01.650.550.925']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Pt(II) complexes with bidentate and tridentate pyrazolyl-containing chelators: synthesis, structural characterization and biological studies. | A series of four Pt(II) complexes anchored by bidentate or tridentate pyrazolyl-alkylamine chelators bearing different substituents at the azolyl rings has been prepared with the aim to assess their interest in the design of novel anticancer drugs. All complexes have been fully characterized by classical analytical met... | ['Cell Line, Tumor', 'Chelating Agents', 'Cisplatin', 'Coordination Complexes', 'Crystallography, X-Ray', 'DNA Damage', 'Drug Resistance, Neoplasm', 'Humans', 'Molecular Conformation', 'Platinum', 'Pyrazoles'] | 21,512,700 | [['A11.251.210.190', 'A11.251.860.180'], ['D27.505.519.914.500', 'D27.720.832.500'], ['D01.210.375', 'D01.625.125', 'D01.710.100'], ['D01.234', 'D02.257'], ['E05.196.309.742.225'], ['G05.200'], ['G07.690.773.984.395'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G02.111.570.820'], ['D01.268.556.690', 'D01.268.95... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Late type III endoleak from graft erosion of an Excluder stent graft: a case report. | We report a case of a late type III endoleak from a hole in the expanded polytetrafluoroethylene graft material of an Excluder bifurcated stent-graft approximately 12 months after implantation. The endoleak was successfully repaired by relining the defect site with an Excluder iliac limb. To our knowledge, this is the ... | ['Aged', 'Aortic Aneurysm, Abdominal', 'Blood Vessel Prosthesis', 'Blood Vessel Prosthesis Implantation', 'Female', 'Humans', 'Postoperative Complications', 'Prosthesis Design', 'Prosthesis Failure', 'Stents', 'Time Factors'] | 16,828,442 | [['M01.060.116.100'], ['C14.907.055.239.075', 'C14.907.109.139.075'], ['E07.695.110'], ['E04.100.814.868.500', 'E04.650.200'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C23.550.767'], ['E05.320.550', 'E07.695.680'], ['C23.550.767.865', 'E05.325.771'], ['E07.695.750'], ['G01.910.857']] | ['Named Groups [M]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Biosynthesis and supramolecular assembly of procollagen IV in neonatal lung. | The rate of biosynthesis of procollagen IV, the principal collagen of basement membranes, and the concentration of specific RNAs coding for procollagen IV were measured in neonatal rat lungs. Both decreased sharply at birth and then recovered again a few days later. The supramolecular assembly of procollagen IV was fol... | ['Age Factors', 'Animals', 'Animals, Newborn', 'Basement Membrane', 'DNA', 'Gene Expression Regulation', 'Gizzard, Non-avian', 'Immunologic Techniques', 'Lung', 'Macromolecular Substances', 'Peptide Fragments', 'Procollagen', 'Rats'] | 3,536,952 | [['N05.715.350.075', 'N06.850.490.250'], ['B01.050'], ['B01.050.050.282'], ['A10.272.220', 'A10.615.179'], ['D13.444.308'], ['G05.308'], ['A13.433'], ['E05.478'], ['A04.411'], ['D05'], ['D12.644.541'], ['D12.776.811.690', 'D12.776.860.300.250.600'], ['B01.050.150.900.649.313.992.635.505.700']] | ['Health Care [N]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The classification of amyloid deposits in clinicopathological practice. | A series of 104 biopsy cases with histopathological proof of amyloid, submitted to our department of pathology over the last 19 years, were re-examined. The survey investigated the medical indication for surgery, the origin and quality of the biopsy and the clinical information as documented on the request form for his... | ['Adult', 'Aged', 'Amyloid', 'Amyloidosis', 'Biopsy', 'Female', 'Humans', 'Immunohistochemistry', 'Male', 'Middle Aged'] | 8,910,040 | [['M01.060.116'], ['M01.060.116.100'], ['D05.500.049', 'D12.776.049'], ['C18.452.845.500'], ['E01.370.225.500.384.100', 'E01.370.225.998.054', 'E01.370.388.100', 'E04.074', 'E05.200.500.384.100', 'E05.200.998.054', 'E05.242.384.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.607.512', 'E01.370... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Disciplines and Occupations [H]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Comparative molecular field analysis and comparative molecular similarity indices analysis of thalidomide analogues as angiogenesis inhibitors. | Thalidomide, 2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione, has been shown to inhibit angiogenesis, the formation of new blood vessels from existing vasculature. As a result, there is renewed interest in this drug as a potential therapy for solid tumors. Thalidomide forms a number of metabolites and has been s... | ['Angiogenesis Inhibitors', 'Animals', 'Aorta, Thoracic', 'In Vitro Techniques', 'Male', 'Microcirculation', 'Models, Molecular', 'Molecular Conformation', 'Muscle, Smooth, Vascular', 'Quantitative Structure-Activity Relationship', 'Rats', 'Rats, Sprague-Dawley', 'Thalidomide'] | 15,084,120 | [['D27.505.696.377.077.099', 'D27.505.696.377.450.100', 'D27.505.954.248.025'], ['B01.050'], ['A07.015.114.056.372'], ['E05.481'], ['G09.330.100.645'], ['E05.599.595'], ['G02.111.570.820'], ['A02.633.570.491', 'A07.015.733.500', 'A10.690.467.491'], ['G02.111.830.500', 'G07.690.773.997.500'], ['B01.050.150.900.649.313.9... | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Development of perceptual completion originates in information acquisition. | Adults have little difficulty perceiving objects as complete despite occlusion, but newborn infants perceive moving partly occluded objects solely in terms of visible surfaces. The developmental mechanisms leading to perceptual completion have never been adequately explained. Here, the authors examine the potential con... | ['Attention', 'Depth Perception', 'Discrimination Learning', 'Eye Movements', 'Female', 'Fixation, Ocular', 'Humans', 'Infant', 'Male', 'Mental Processes', 'Motion Perception', 'Orientation', 'Pattern Recognition, Visual', 'Perceptual Closure', 'Perceptual Masking', 'Psychology, Child', 'Pursuit, Smooth'] | 18,793,055 | [['F02.830.104.214'], ['F02.463.593.200', 'F02.463.593.778.255'], ['F02.463.425.280'], ['G11.427.410.140', 'G14.350'], ['G14.350.253'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703'], ['F02.463'], ['F02.463.593.932.567'], ['F01.058.577', 'F02.830.606'], ['F02.463.593.524.500', 'F02.463.593.932.622'], ... | ['Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Named Groups [M]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Systems-based approaches enable identification of gene targets which improve the flavour profile of low-ethanol wine yeast strains. | Metabolic engineering has been vital to the development of industrial microbes such as the yeast Saccharomyces cerevisiae. However, sequential rounds of modification are often needed to achieve particular industrial design targets. Systems biology approaches can aid in identifying genetic targets for modification throu... | ['Flavoring Agents', 'Genes, Fungal', 'Genomics', 'Metabolic Engineering', 'Saccharomyces cerevisiae'] | 30,138,679 | [['D26.650.294', 'D27.720.372.300.353', 'D27.720.744.294', 'G07.203.300.514.500.400', 'J02.500.514.500.400'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['H01.158.273.180.350', 'H01.158.273.343.350'], ['E05.393.420.526', 'E05.481.500.311.249', 'J01.293.069.249.249'], ['B01.30... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]', 'Disciplines and Occupations [H]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 |
Glial reaction in the hippocampal formation is highly correlated with aging in human brain. | Glial fibrillary acidic protein (GFAP), a biochemical marker of astrocytes and glial reaction, was quantified by immunoblotting in different brain areas from 33 non-demented patients with a Mini Mental State Examination score above 26 and aged from 12 to 98 years. An increase of GFAP with age was first found in the hip... | ['Adolescent', 'Adult', 'Aged', 'Aged, 80 and over', 'Aging', 'Entorhinal Cortex', 'Frontal Lobe', 'Glial Fibrillary Acidic Protein', 'Hippocampus', 'Humans', 'Immunoblotting', 'Immunohistochemistry', 'Middle Aged', 'Neurofibrillary Tangles', 'Neuroglia', 'Parietal Lobe', 'Plaque, Amyloid', 'Temporal Lobe'] | 9,389,594 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['G07.345.124'], ['A08.186.211.180.590.750.225', 'A08.186.211.180.710.225', 'A08.186.211.200.885.287.500.382.750.225', 'A08.186.211.200.885.287.500.620.562', 'A08.186.211.200.885.287.500.814.695.374', 'A08.186.211.200.885.287.750.562'], ['... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 |
Effects of oral administration of meloxicam, carprofen, and a nutraceutical on thyroid function in dogs with osteoarthritis. | The purpose of this study was to evaluate the effect of the administration of meloxicam; carprofen; and a slow-acting disease modifying osteoarthritis agent, that contains chondroitin sulfate, purified glucosamine, and manganese ascorbate (CS-G-M), on thyroid function in dogs. Forty-six healthy (except for osteoarthrit... | ['Administration, Oral', 'Animals', 'Anti-Inflammatory Agents, Non-Steroidal', 'Autoantibodies', 'Carbazoles', 'Chondroitin Sulfates', 'Dog Diseases', 'Dogs', 'Female', 'Glucosamine', 'Longitudinal Studies', 'Male', 'Manganese Compounds', 'Meloxicam', 'Osteoarthritis', 'Random Allocation', 'Thiazines', 'Thiazoles', 'Th... | 12,839,241 | [['E02.319.267.100'], ['B01.050'], ['D27.505.696.663.850.014.040.500', 'D27.505.954.158.030', 'D27.505.954.329.030'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['D03.633.100.473.144', 'D03.633.300.148'], ['D09.698.373.200.300'], ['C22.268'], ['B01.050.150.900.649.313... | ['Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Chemicals and Drugs [D]', 'Diseases [C]', 'Health Care [N]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
In vitro study of hormone degradation by heart-lung machine with bubble oxygenator. | In the present experiment with heart-lung machine set in a closed system in vitro, the blood containing increased levels of hormones was circulated at 30 degrees C for 90 min and at 37 degrees C for 30 min; a fraction of the priming perfusate was studied in parallel at the same temperatures in an incubator. The level o... | ['Catecholamines', 'Extracorporeal Circulation', 'Growth Hormone', 'Heart-Lung Machine', 'Hormones', 'Humans', 'Hydrocortisone', 'In Vitro Techniques', 'Insulin', 'Oxygenators', 'Thyroxine'] | 6,322,267 | [['D02.092.311', 'D02.455.426.559.389.657.166.175'], ['E04.292'], ['D06.472.699.631.525.425', 'D12.644.548.691.525.425'], ['E07.858.082.458'], ['D06.472', 'D27.505.696.399.472'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D04.210.500.745.745.654.600', 'D06.472.040.585.353.476', 'D06.472.040.585.478.392'], ['E05... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]'] | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Imaging recognition events between human IgG and rat anti-human IgG by atomic force microscopy. | Chemically immobilized rat anti-human immunoglobulin (IgG) monolayers on thiols modified gold substrates were fabricated using self-assembled monolayer (SAM) method. The antibody monolayers were imaged before and after free human IgG treated, whilst recognition events between antigen and antibody were monitored by cont... | ['Animals', 'Antibodies, Anti-Idiotypic', 'Antigen-Antibody Complex', 'Gold', 'Humans', 'Imaging, Three-Dimensional', 'Immunoglobulin G', 'Microscopy, Atomic Force', 'Nanostructures', 'Particle Size', 'Rats'] | 20,813,125 | [['B01.050'], ['D12.776.124.486.485.114.071', 'D12.776.124.790.651.114.071', 'D12.776.377.715.548.114.071'], ['D12.776.124.486.485.114.257', 'D12.776.124.790.651.114.257', 'D12.776.377.715.548.114.257', 'D23.050.101'], ['D01.268.556.322', 'D01.268.956.186', 'D01.552.544.322'], ['B01.050.150.900.649.313.988.400.112.400.... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Information Science [L]', 'Technology, Industry, and Agriculture [J]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 |
Immunological myelin disruption does not alter expression of regeneration-associated genes in intact or axotomized rubrospinal neurons. | The inability of axotomized neurons to regenerate within the CNS has been partially attributed to a number of inhibitory factors associated with CNS myelin that are extrinsic to the severed neurons. However, some neurons are capable of limited regeneration after injury and this ability has been shown to correlate with ... | ['Animals', 'Axons', 'Axotomy', 'GAP-43 Protein', 'Gene Expression Regulation', 'In Situ Hybridization', 'Male', 'Myelin Sheath', 'Nerve Regeneration', 'Neurons', 'RNA, Messenger', 'Rats', 'Rats, Sprague-Dawley', 'Red Nucleus', 'Spinal Cord', 'Spinal Cord Injuries', 'Thoracic Vertebrae', 'Tubulin'] | 10,785,453 | [['B01.050'], ['A08.675.542.145', 'A11.284.180.075', 'A11.671.137', 'A11.671.501.145'], ['E04.525.210.158'], ['D12.776.395.550.400', 'D12.776.543.550.400', 'D12.776.631.400'], ['G05.308'], ['E01.370.225.500.620.670.325', 'E01.370.225.750.600.670.325', 'E05.200.500.620.670.325', 'E05.200.750.600.670.325', 'E05.393.661.4... | ['Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Antioxidant properties of antiulcer Kampo medicines. | Kampo medicines, aqueous extracts of a mixture of natural crude drugs, have numerous ingredients. Recent pharmacologic studies on Kampo medicines have clarified their many and varied biological activities. In this study, based on recent research that has been directed toward the excellent antioxidant properties of Kamp... | ['Antioxidants', 'Electron Spin Resonance Spectroscopy', 'Humans', 'Hydroxides', 'Medicine, Chinese Traditional', 'Neutrophils', 'Peptic Ulcer', 'Reactive Oxygen Species', 'Respiratory Burst', 'Superoxides'] | 8,282,212 | [['D27.505.519.217', 'D27.505.696.706.125', 'D27.720.799.047'], ['E05.196.867.519.274'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['D01.045.250', 'D01.248.497.158.459'], ['E02.190.488.585.520', 'I01.076.201.450.654.558.520'], ['A11.118.637.415.583', 'A11.627.340.583', 'A11.733.689', 'A15.145.229.637.415.583', '... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Anatomy [A]', 'Diseases [C]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
Influence of secondary preparative parameters and aging effects on PLGA particle size distribution: a sedimentation field flow fractionation investigation. | Poly(lactic-co-glycolic acid) particles in the 200-400-nm size range were formulated through nanoprecipitation and solvent evaporation methods. Different concentrations of the polymer and stabilizer (Pluronic® F 68) were tested in order to identify the best conditions for making poly(lactic-co-glycolic acid) particles ... | ['Drug Carriers', 'Drug Delivery Systems', 'Fractionation, Field Flow', 'Lactic Acid', 'Particle Size', 'Polyglycolic Acid', 'Polylactic Acid-Polyglycolic Acid Copolymer', 'Surface Properties'] | 22,644,156 | [['D26.255.260', 'E02.319.300.380'], ['E02.319.300'], ['E05.196.155.500'], ['D02.241.511.459.450'], ['G02.712'], ['D05.750.728.780', 'D25.720.728.780', 'J01.637.051.720.728.780'], ['D02.241.511.459.450.500', 'D05.750.728.780.500', 'D25.720.728.780.500', 'J01.637.051.720.728.780.500'], ['G02.860']] | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Ethylene regulation of carotenoid accumulation and carotenogenic gene expression in colour-contrasted apricot varieties (Prunus armeniaca). | In order to elucidate the regulation mechanisms of carotenoid biosynthesis in apricot fruit (Prunus armeniaca), carotenoid content and carotenogenic gene expression were analysed as a function of ethylene production in two colour-contrasted apricot varieties. Fruits from Goldrich (GO) were orange, while Moniqui (MO) fr... | ['Carotenoids', 'Color', 'Cyclopropanes', 'Ethylenes', 'Fruit', 'Gene Expression Regulation, Plant', 'Plant Growth Regulators', 'Prunus'] | 15,911,563 | [['D02.455.326.271.665.202', 'D02.455.426.392.368.367.379.249', 'D02.455.849.131', 'D23.767.261'], ['G01.590.540.199'], ['D02.455.426.392.368.533'], ['D02.455.326.271.367'], ['A18.024.500', 'G07.203.300.562', 'J02.500.562'], ['G05.308.375'], ['D27.505.696.377.760'], ['B01.650.940.800.575.912.250.859.937.500.625']] | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Comparative cranial CT enhancement in a primate model of cerebral infarction. | The value of various enhancement techniques as opposed to nonenhanced CT scanning was compared in 15 baboons with cerebral infarction secondary to embolization of the left middle cerebral artery. The most prominent CT findings in infarction included an area of low absorption in the opercula--basal ganglia--centrum semi... | ['Animals', 'Cerebral Infarction', 'Disease Models, Animal', 'Injections, Spinal', 'Metrizamide', 'Papio', 'Radiographic Image Enhancement', 'Tomography, X-Ray Computed'] | 581,830 | [] | [] | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Enhanced expression of a furin-cleavable proinsulin. | Cell engineering or gene therapy may represent an alternative to current methods of treating diabetes mellitus. Cells could be engineered to secrete insulin ex vivo for transplantation or the insulin gene could be administered directly by injection into muscle. A problem has been that non-neuroendocrine cells lack the ... | ['Amino Acid Sequence', 'Amino Acid Substitution', 'Animals', 'Cells, Cultured', 'Cloning, Molecular', 'CpG Islands', 'Dactinomycin', 'Furin', 'Genetic Therapy', 'Humans', 'Insulin', 'Mice', 'Molecular Sequence Data', 'Muscles', 'Proinsulin', 'RNA Stability', 'Rats'] | 14,664,719 | [['G02.111.570.060', 'L01.453.245.667.060'], ['E05.393.420.601.035', 'G05.558.109'], ['B01.050'], ['A11.251'], ['E05.393.220'], ['G02.111.570.080.380.160', 'G05.360.080.380.160', 'G05.360.340.024.159'], ['D03.633.300.200', 'D04.345.566.252', 'D12.644.641.252'], ['D08.811.277.656.300.760.353', 'D08.811.277.656.837.249',... | ['Phenomena and Processes [G]', 'Information Science [L]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Does India need an indigenous HPV vaccine and why? | Cervical cancer is the most common form of cancer in Indian women, causing high morbidity and mortality. Two effective and safe vaccines exist, but these remain out of reach of most people due to their high cost. It is imperative that an Human Papillomavirus (HPV) vaccine be affordable and cheap so that the target popu... | ['Female', 'Health Policy', 'Health Services Needs and Demand', 'Humans', 'India', 'Papillomavirus Vaccines', 'Prevalence', 'Uterine Cervical Neoplasms', 'Viral Vaccines'] | 23,447,031 | [['I01.655.500.608.400', 'I01.880.604.825.608.400', 'N03.623.500.608.428'], ['N03.349.380.420', 'N05.300.450'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['Z01.252.245.393'], ['D20.215.894.899.498'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750'],... | ['Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Diseases [C]'] | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Nasal high-flow versus Venturi mask oxygen therapy after extubation. Effects on oxygenation, comfort, and clinical outcome. | RATIONALE: Oxygen is commonly administered after extubation. Although several devices are available, data about their clinical efficacy are scarce.OBJECTIVES: To compare the effects of the Venturi mask and the nasal high-flow (NHF) therapy on PaO2/FiO2SET ratio after extubation. Secondary endpoints were to assess effec... | ['Aged', 'Airway Extubation', 'Female', 'Humans', 'Intubation, Intratracheal', 'Italy', 'Male', 'Masks', 'Middle Aged', 'Oxygen Inhalation Therapy', 'Respiratory Distress Syndrome', 'Ventilator Weaning'] | 25,003,980 | [['M01.060.116.100'], ['E02.041.249', 'E05.008'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.041.500', 'E02.585.578', 'E05.497.578'], ['Z01.542.489'], ['E07.325.877.500', 'E07.700.500', 'E07.858.594.750', 'J01.637.708.560.782'], ['M01.060.116.630'], ['E02.880.690'], ['C08.381.840', 'C08.618.840'], ['E02.041... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Geographicals [Z]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 |
Prognostic markers in diarrhoea-associated haemolytic-uraemic syndrome: initial neutrophil count, human neutrophil elastase and von Willebrand factor antigen. | The observed increase in plasma von Willebrand factor antigen (vWF:Ag) in patients with the haemolytic-uraemic syndrome is presumed to be secondary to endothelial damage, which is a central event in these diseases. As the prognostic value of such changes has not been previously evaluated, vWF:Ag has been measured in pl... | ['Antigens', 'Child', 'Diarrhea', 'Escherichia coli Infections', 'Hemolytic-Uremic Syndrome', 'Humans', 'Leukocyte Count', 'Neutrophils', 'Pancreatic Elastase', 'Prognosis', 'von Willebrand Factor'] | 1,881,576 | [['D23.050'], ['M01.060.406'], ['C23.888.821.214'], ['C01.150.252.400.310.330'], ['C12.777.419.936.463', 'C13.351.968.419.936.463', 'C15.378.071.141.610', 'C15.378.140.855.925.500'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.225.500.195.107.595', 'E01.370.225.625.107.595', 'E05.200.500.195.107.595', 'E... | ['Chemicals and Drugs [D]', 'Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Dose reduction in helical CT: dynamically adjustable z-axis X-ray beam collimation. | OBJECTIVE: The purpose of this study was to measure the dose reduction achieved with dynamically adjustable z-axis collimation.MATERIALS AND METHODS: A commercial CT system was used to acquire CT scans with and without dynamic z-axis collimation. Dose reduction was measured as a function of pitch, scan length, and posi... | ['Humans', 'Phantoms, Imaging', 'Radiation Dosage', 'Radiation Protection', 'Tomography, Spiral Computed'] | 20,028,890 | [['B01.050.150.900.649.313.988.400.112.400.400'], ['E07.671'], ['E05.799.513', 'G01.750.740', 'N06.850.810.250'], ['N06.850.810.425'], ['E01.370.350.350.810.800', 'E01.370.350.600.350.700.810.800', 'E01.370.350.700.700.810.800', 'E01.370.350.700.810.810.800', 'E01.370.350.825.810.810.800']] | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Surveillance of patients affected by Peutz-Jeghers syndrome: diagnostic value of MR enterography in prone and supine position. | INTRODUCTION: Peutz-Jeghers syndrome (PJS) is a familial polyposis syndrome characterized by multiple hamartomatous polyps throughout the gastrointestinal tract. The aim of our study was to retrospectively determine the diagnostic value of MR enterography (MRE), performed in supine and prone position, in the detection ... | ['Adult', 'Contrast Media', 'Endoscopy', 'Female', 'Humans', 'Image Interpretation, Computer-Assisted', 'Magnetic Resonance Imaging', 'Male', 'Middle Aged', 'Peutz-Jeghers Syndrome', 'Population Surveillance', 'Prone Position', 'Retrospective Studies', 'Statistics, Nonparametric', 'Supine Position'] | 21,538,021 | [['M01.060.116'], ['D27.505.259.500', 'D27.720.259'], ['E01.370.388.250', 'E04.502.250'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.158.600', 'E01.370.350.350', 'L01.313.500.750.100.158.600'], ['E01.370.350.825.500'], ['M01.060.116.630'], ['C04.700.633', 'C06.405.469.578.750', 'C16.320.700.667', 'C17.800.6... | ['Named Groups [M]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Information Science [L]', 'Diseases [C]', 'Health Care [N]', 'Phenomena and Processes [G]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
The positive effects of postnatal handling on defensive burying are more obvious in a situation that enlarges the potential coping responses. | A recent study reported few effects of postnatal handling in the defensive burying test. Since the importance of testing conditions has been emphasised in this paradigm, the lack of handling effects in this test could be attributed to the testing situation. Our experiment was carried out to test whether postnatal handl... | ['Adaptation, Psychological', 'Animals', 'Animals, Newborn', 'Anxiety', 'Habituation, Psychophysiologic', 'Handling, Psychological', 'Male', 'Rats', 'Rats, Inbred Strains'] | 12,385,791 | [['F01.058'], ['B01.050'], ['B01.050.050.282'], ['F01.470.132'], ['F02.463.425.393', 'F02.830.422', 'G11.561.312'], ['F01.658.556'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400']] | ['Psychiatry and Psychology [F]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
High affinity hydroxypiperidine analogues of 4-(2-benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidine for the dopamine transporter: stereospecific interactions in vitro and in vivo. | In our effort to develop high-affinity ligands for the dopamine transporter which might find potential use as cocaine medication, a polar hydroxy substituent was introduced into the piperidine ring of one of our disubstituted lead analogues derived from 1-[2-(diphenylmethoxy)-ethyl]-4-(3-phenylpropyl)piperazine (GBR 12... | ['Animals', 'Benzhydryl Compounds', 'Carrier Proteins', 'Cerebral Cortex', 'Cocaine', 'Corpus Striatum', 'Crystallography, X-Ray', 'Discrimination Learning', 'Dopamine', 'Dopamine Plasma Membrane Transport Proteins', 'Dopamine Uptake Inhibitors', 'In Vitro Techniques', 'Ligands', 'Male', 'Membrane Glycoproteins', 'Memb... | 12,646,032 | [['B01.050'], ['D02.455.426.559.389.115'], ['D12.776.157'], ['A08.186.211.200.885.287.500'], ['D02.145.074.722.388', 'D03.132.889.354', 'D03.605.084.500.722.388', 'D03.605.869.388'], ['A08.186.211.200.885.287.249.487'], ['E05.196.309.742.225'], ['F02.463.425.280'], ['D02.092.211.215.406', 'D02.092.311.342', 'D02.455.42... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Role of sublethal injury in decline of bacterial populations in lake water. | Following their addition to lake water, the populations of Escherichia coli and of antibiotic-resistant strains of Pseudomonas fluorescens, Agrobacterium tumefaciens, Micrococcus flavus, Rhizobium meliloti, and Klebsiella pneumoniae declined rapidly, as determined by counting on media containing antibacterial compounds... | ['Bacteria', 'Colony Count, Microbial', 'Culture Media', 'Escherichia coli', 'Fresh Water', 'Klebsiella pneumoniae', 'Micrococcus', 'Pseudomonas fluorescens', 'Rhizobium', 'Water Microbiology'] | 3,145,714 | [['B03'], ['E01.370.225.875.220', 'E05.200.875.220'], ['D27.720.470.305', 'E07.206'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['G16.500.275.280', 'N06.230.232'], ['B03.440.450.425.425.600', 'B03.660.250.150.400.590'], ['B03.510.024.850.500', 'B03.510.400.500.500'], ['B03.440.400.425.625.625.325', 'B03.6... | ['Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Health Care [N]', 'Disciplines and Occupations [H]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
Quantification of main bioactive metabolites from saffron (Crocus sativus) stigmas by a micellar electrokinetic chromatographic (MEKC) method. | Saffron is an expensive spice, cultivated in many regions of the world. Its chief metabolites include crocins, which are responsible for the coloring ability, safranal, which is the main essential oil constituent, and picrocrocin which is the main bitter constituent of the spice. A simple micellar capillary electrochro... | ['Carotenoids', 'Chromatography, Micellar Electrokinetic Capillary', 'Crocus', 'Cyclohexenes', 'Electrolytes', 'Glucosides', 'Hydrogen-Ion Concentration', 'Limit of Detection', 'Micelles', 'Plant Extracts', 'Sodium Dodecyl Sulfate', 'Solvents', 'Terpenes'] | 22,464,563 | [['D02.455.326.271.665.202', 'D02.455.426.392.368.367.379.249', 'D02.455.849.131', 'D23.767.261'], ['E05.196.181.500'], ['B01.650.940.800.575.912.250.618.100.400.500'], ['D02.455.426.392.368.367.379'], ['D01.248'], ['D09.408.348'], ['G02.300'], ['E05.318.740.872.374', 'N05.715.360.750.725.500', 'N06.850.520.830.872.500... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
The sequence of gene expression in cultured human saphenous vein after injury. | OBJECTIVE: The objective of this study was a description of changes in gene expression that occur in response to mechanical injury of cultured human saphenous vein.METHODS: Restriction fragment differential display (Display Systems Biotech, Vista, Calif) was used for the comparison of the gene expression profile in sev... | ['Cell Movement', 'Culture Techniques', 'Gene Expression', 'Gene Expression Profiling', 'Humans', 'Polymorphism, Restriction Fragment Length', 'Saphenous Vein', 'Sequence Analysis', 'Time Factors'] | 11,802,146 | [['G04.198', 'G07.568.500.180'], ['E05.481.500'], ['G05.297'], ['E05.393.332'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.365.795.595'], ['A07.015.908.819'], ['E05.393.760'], ['G01.910.857']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Anatomy [A]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Adrenal myelolipomas: CT appearance with tiny amounts of fat and punctate calcification. | Five cases of myelolipoma of the adrenal are presented which contained only tiny foci of fat along with areas of punctate calcification. This computed tomographic (CT) appearance is less common for this neoplasm and has only been described in three of 26 previously published CT cases of this adrenal tumor. The presence... | ['Adrenal Cortex Neoplasms', 'Aged', 'Calcinosis', 'Female', 'Humans', 'Lipoma', 'Male', 'Middle Aged', 'Tomography, X-Ray Computed'] | 2,595,871 | [['C04.588.322.078.265', 'C19.053.098.265', 'C19.053.347.500', 'C19.344.078.265'], ['M01.060.116.100'], ['C18.452.174.130'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C04.557.450.550.400'], ['M01.060.116.630'], ['E01.370.350.350.810', 'E01.370.350.600.350.700.810', 'E01.370.350.700.700.810', 'E01.370.350.700.8... | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Regulation of lipolysis and cyclic AMP synthesis through energy supply in isolated human fat cells. | The effects of glucose and of various inhibitors of glycolysis or of oxidative phosphorylation on stimulated lipolysis and on intracellular cyclic AMP and ATP levels were investigated in isolated human fat cells. The glycolysis inhibitors, NaF and monoiodoacetate, inhibited epinephrine or theophylline-stimulated lipoly... | ['Adipose Tissue', 'Antimycin A', 'Bucladesine', 'Cyclic AMP', 'Dinitrophenols', 'Epinephrine', 'Ethylmaleimide', 'Fluorides', 'Humans', 'In Vitro Techniques', 'Iodoacetates', 'Lipid Mobilization', 'Omentum', 'Theophylline'] | 189,821 | [['A10.165.114'], ['D02.540.576.500.750'], ['D03.633.100.759.646.138.395.250', 'D13.695.462.200.250', 'D13.695.667.138.395.250', 'D13.695.827.068.395.250'], ['D03.633.100.759.646.138.395', 'D13.695.462.200', 'D13.695.667.138.395', 'D13.695.827.068.395'], ['D02.455.426.559.389.657.566.304', 'D02.640.743.304'], ['D02.033... | ['Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Frequency domain fluorometry: theory and application. | Frequency domain fluorometry is a widely utilized tool in the physical, chemical, and biological sciences. This chapter focuses on the theory of the method and the practical aspects required to carry out intensity decay, i.e., lifetime measurements on a modern frequency domain fluorometer. Several chemical/biological s... | ['Fluorescence', 'Fluorometry', 'Models, Molecular', 'Molecular Biology'] | 24,108,624 | [['G01.358.500.505.650.665.500', 'G01.590.540.665.500'], ['E05.196.712.516.600'], ['E05.599.595'], ['H01.158.201.636', 'H01.158.273.343.595', 'H01.181.122.650']] | ['Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Disciplines and Occupations [H]'] | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Culture moderates children's responses to ostracism situations. | Across a series of studies, we investigated cultural differences in children's responses to ostracism situations. Working with the children of farmers and herders, we focused on how painful children estimate ostracism to be. Study 1a showed that 4- to 8-year-old children from a socially interdependent farming community... | ['Child', 'Child Behavior', 'Child, Preschool', 'Cross-Cultural Comparison', 'Female', 'Humans', 'Male', 'Rural Population', 'Social Isolation', 'Social Perception', 'Social Support', 'Turkey'] | 27,176,774 | [['M01.060.406'], ['F01.145.179'], ['M01.060.406.448'], ['I01.076.201.450.281', 'I01.880.853.100.257'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['N01.600.725'], ['F01.145.813.781', 'I01.880.853.748'], ['F02.463.593.752'], ['I01.880.853.500.600'], ['Z01.252.245.500.850']] | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]', 'Health Care [N]', 'Geographicals [Z]'] | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Role of 5-hydroxytryptamine (serotonin) in oral glucose intolerance. | The aim of the present study was to investigate the metabolic base of psychoneurological symptoms, most notably tiredness and loss of concentration ability, appearing after carbohydrate-rich meals and during oral glucose tolerance tests. Such metabolic changes may be the cause of many accidents attributed to the "human... | ['Adult', 'Animals', 'Fatigue', 'Female', 'Glucose', 'Glucose Tolerance Test', 'Humans', 'Hypoglycemia', 'Intestinal Absorption', 'Intestinal Mucosa', 'Male', 'Motor Activity', 'Psychological Tests', 'Psychophysiologic Disorders', 'Serotonin', 'Swine', 'Vision Tests'] | 6,581,528 | [['M01.060.116'], ['B01.050'], ['C23.888.369'], ['D09.947.875.359.448'], ['E01.370.225.124.100.355', 'E01.370.374.355', 'E05.200.124.100.355'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C18.452.394.984'], ['G03.015.500.374.500', 'G03.787.024.500.374.500', 'G07.203.650.372.500', 'G07.690.725.015.500.374.500', '... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Psychiatry and Psychology [F]'] | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
The three human T-lymphotropic virus type I subtypes arose from three geographically distinct simian reservoirs. | To investigate the origin of human T-lymphotropic virus I (HTLV-I), strains of diverse geographical origin were analysed. We sequenced the LTR and env genes of HTLV-I strains from Brazil, Central African Republic, Taiwan and Zaire, and the simian T-lymphotropic virus type I (STLV-I) strain PHSu1 from a baboon from the ... | ['Animals', 'Base Sequence', 'Genes, env', 'Human T-lymphotropic virus 1', 'Humans', 'Molecular Sequence Data', 'Papio', 'Phylogeny', 'Repetitive Sequences, Nucleic Acid', 'Simian T-lymphotropic virus 1'] | 8,627,240 | [['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['G05.360.340.024.340.364.875.172', 'G05.360.340.358.024.875.172', 'G05.360.340.358.840.500.172'], ['B04.613.807.200.725.400', 'B04.820.650.200.725.400'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.453.245.667'], ['B01.050.150.900.649.... | ['Organisms [B]', 'Phenomena and Processes [G]', 'Information Science [L]'] | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
Effects of portion size and energy density on young children's intake at a meal. | BACKGROUND: Large portions of energy-dense foods are one feature of obesity-promoting dietary environments. Entr?e portion size has been shown to influence energy intake at meals by young children. The role of energy density (ED) in children's response to portion size, however, is unknown.OBJECTIVE: We aimed to test th... | ['Child', 'Child, Preschool', 'Eating', 'Energy Intake', 'Feeding Behavior', 'Female', 'Humans', 'Male'] | 17,616,778 | [['M01.060.406'], ['M01.060.406.448'], ['G07.203.650.283', 'G10.261.330'], ['G07.203.650.240.340'], ['F01.145.113.547', 'F01.145.407', 'G07.203.650.353'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Psychiatry and Psychology [F]', 'Organisms [B]'] | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Mostly heterosexual and mostly gay/lesbian: evidence for new sexual orientation identities. | A sample of 1,784 individuals responded to an online survey advertised on the Facebook social networking website. We explored the sexual orientation continuum by focusing on three components: self-reported sexual orientation identity, sexual attraction, and sexual partners. Results supported a 5-category classification... | ['Adolescent', 'Adult', 'Aged', 'Female', 'Humans', 'Internet', 'Male', 'Middle Aged', 'Self Concept', 'Sexual Behavior', 'Sexual Partners', 'Sexuality', 'Surveys and Questionnaires'] | 22,327,566 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['L01.224.230.110.500'], ['M01.060.116.630'], ['F01.752.747.792'], ['F01.145.802'], ['M01.778'], ['F01.145.802.975', 'G08.686.867'], ['E05.318.308.980', 'N05.715.360.300.800', 'N06.850.520.308.980']] | ['Named Groups [M]', 'Organisms [B]', 'Information Science [L]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]'] | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 1 | 1 | 0 |
Phosphorylation of isocitrate dehydrogenase in Escherichia coli mutants with a non-functional glyoxylate cycle. | The phosphorylation of NADP-specific isocitrate dehydrogenase in an isocitrate lyase and in a malate synthase mutant of Escherichia coli has been investigated. The results clearly demonstrate that isocitrate dehydrogenase may undergo an acetate-induced phosphorylation in organisms which do not have a functional glyoxyl... | ['Bacterial Proteins', 'Escherichia coli', 'Glyoxylates', 'Isocitrate Dehydrogenase', 'Mutation', 'Phosphorylation'] | 6,347,712 | [['D12.776.097'], ['B03.440.450.425.325.300', 'B03.660.250.150.180.100'], ['D02.241.152.367'], ['D08.811.682.047.820.475'], ['G05.365.590'], ['G02.111.665', 'G02.607.780', 'G03.796']] | ['Chemicals and Drugs [D]', 'Organisms [B]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Association between ruptured membranes, tocolytic therapy, and respiratory distress syndrome. | Two hundred ninety-seven patients from the placebo group of the National Institutes of Health Collaborative Study on Antenatal Steroid Therapy for prevention of respiratory distress syndrome were selected for analysis to investigate a possible association between premature rupture of the membranes, tocolytic therapy, a... | ['Amniotic Fluid', 'Female', 'Fetal Membranes, Premature Rupture', 'Humans', 'Infant, Newborn', 'Isoxsuprine', 'Obstetric Labor, Premature', 'Phosphatidylcholines', 'Pregnancy', 'Respiratory Distress Syndrome, Newborn', 'Sphingomyelins'] | 6,695,972 | [['A12.098', 'A16.378.149'], ['C13.703.420.339'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.703.520'], ['D02.033.100.624.427', 'D02.033.755.624.427', 'D02.092.471.683.560'], ['C13.703.420.491'], ['D10.570.755.375.760.400.800'], ['G08.686.784.769'], ['C08.381.840.500', 'C08.618.840.500', 'C16.614.521.56... | ['Anatomy [A]', 'Diseases [C]', 'Organisms [B]', 'Named Groups [M]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Hemicholinium-3 binding: correlation with high-affinity choline uptake during changes in cholinergic activity. | The binding of hemicholinium-3 was measured in the cerebral cortex, hippocampus, and striatum after treatment with cholinergic agonists and antagonists in order to examine its utility as an index of presynaptic cholinergic regulation. The binding of muscarinic receptors and the high affinity uptake of choline were exam... | ['Animals', 'Choline', 'Hemicholinium 3', 'Ligands', 'Male', 'Parasympathetic Nervous System', 'Rats', 'Rats, Inbred Strains', 'Receptors, Muscarinic', 'Specimen Handling'] | 3,419,544 | [['B01.050'], ['D02.033.100.291.211', 'D02.092.063.291.211', 'D02.092.877.883.333', 'D02.675.276.232'], ['D02.092.877.435', 'D02.675.276.435'], ['D27.720.470.480'], ['A08.800.050.600'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.050.199.520.760', 'B01.050.150.900.649.313.992.635.505.700.400'], ['D12.776.543... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Genetic Reduction in Left Ventricular Protein Kinase C-á and Adverse Ventricular Remodeling in Human Subjects. | BACKGROUND: Inhibition of PKC-á (protein kinase C-á) enhances contractility and cardioprotection in animal models, but effects in humans are unknown. Genotypes at rs9912468 strongly associate with PRKCA expression in the left ventricle, enabling genetic approaches to measure effects of reduced PKC-á in human population... | ['Adult', 'Aged', 'Alleles', 'Animals', 'Female', 'Genes, Reporter', 'Genetic Predisposition to Disease', 'Genotype', 'Haplotypes', 'Heart Ventricles', 'Homozygote', 'Humans', 'Introns', 'Linkage Disequilibrium', 'Male', 'Middle Aged', 'Protein Kinase C-alpha', 'Quantitative Trait Loci', 'Ventricular Remodeling', 'Zebr... | 29,540,468 | [['M01.060.116'], ['M01.060.116.100'], ['G05.360.340.024.340.030'], ['B01.050'], ['G05.360.340.024.340.435'], ['C23.550.291.687.500', 'G05.380.355'], ['G05.380'], ['G05.380.360'], ['A07.541.560'], ['G05.380.554'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G05.360.340.024.220.400', 'G05.360.340.024.340.137.515'... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Organisms [B]', 'Diseases [C]', 'Anatomy [A]', 'Chemicals and Drugs [D]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Efficacy of various pyrethroid structures against a highly metabolically resistant isogenic strain of Helicoverpa armigera (Lepidoptera: Noctuidae) from China. | BACKGROUND: Resistance to pyrethroids and other types of insecticides in Helicoverpa armigera (H?bner) has been documented in many countries. The isolation of specific resistance mechanisms in isogenic strains is an optimal approach to investigate cross-resistance pattern, and to validate resistance breaking pyrethroid... | ['Animals', 'China', 'Insecticide Resistance', 'Insecticides', 'Molecular Structure', 'Moths', 'Pesticide Synergists', 'Piperonyl Butoxide', 'Pyrethrins'] | 17,685,437 | [['B01.050'], ['Z01.252.474.164'], ['G07.690.773.984.491'], ['D27.720.031.700.491', 'D27.888.723.491'], ['G02.111.570', 'G02.466'], ['B01.050.500.131.617.720.500.500.937.650'], ['D27.720.031.700.748', 'D27.888.723.748'], ['D03.383.246.118.600', 'D03.633.100.115.600'], ['D02.455.849.575.188.750']] | ['Organisms [B]', 'Geographicals [Z]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Self-assembled nanoparticles comprising aptide-SN38 conjugates for use in targeted cancer therapy. | Self-assembled nanoparticles (NPs) have been intensively utilized as cancer drug delivery carriers because hydrophobic anticancer drugs may be efficiently loaded into the particle cores. In this study, we synthesized and evaluated the therapeutic index of self-assembled NPs chemically conjugated to a fibronectin extra ... | ['Animals', 'Antineoplastic Agents', 'Cell Line, Tumor', 'Drug Carriers', 'Mice', 'Mice, Inbred BALB C', 'Nanoparticles', 'Neoplasms'] | 27,804,918 | [['B01.050'], ['D27.505.954.248'], ['A11.251.210.190', 'A11.251.860.180'], ['D26.255.260', 'E02.319.300.380'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.338', 'B01.050.150.900.649.313.992.635.505.500.400.338'], ['J01.637.512.600'], ['C04']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Technology, Industry, and Agriculture [J]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Effect of 12-O-tetradecanoylphorbol-13-acetate (TPA) on the growth inhibitory and increased phosphatidylinositol (PI) responses induced by epidermal growth factor (EGF) in A431 cells. | Epidermal growth factor (EGF) inhibited the growth of A431 human epidermoid carcinoma cells. The tumor promoting, phorbol ester, 12-O-tetradecanoylphorbol-13-acetate (TPA) also retarded A431 cell growth. Addition of both TPA and EGF inhibited cell growth in an additive or synergistic manner depending upon the initial p... | ['Carcinoma, Squamous Cell', 'Cell Division', 'Cell Line', 'Diglycerides', 'Epidermal Growth Factor', 'ErbB Receptors', 'Humans', 'Phorbol Esters', 'Phorbols', 'Phosphatidylinositols', 'Receptors, Cell Surface', 'Tetradecanoylphorbol Acetate'] | 6,311,852 | [['C04.557.470.200.400', 'C04.557.470.700.400'], ['G04.144.220', 'G04.161.750.500', 'G05.113', 'G07.345.249.410.750.500'], ['A11.251.210'], ['D10.351.303'], ['D06.472.317.350', 'D12.644.276.382.500', 'D12.776.467.382.500', 'D23.529.382.500'], ['D08.811.913.696.620.682.725.400.009', 'D12.776.543.750.630.009', 'D12.776.5... | ['Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Chemicals and Drugs [D]', 'Organisms [B]'] | 1 | 1 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Rapid retrovirus titration using competitive polymerase chain reaction. | A quantitative polymerase chain reaction (PCR) procedure has been developed for rapid retrovirus titration. This procedure, which is based on the simultaneous amplification of the sample with known amounts of a competitor DNA fragment (competitive PCR), was used for the quantification of viral RNA genomes in retrovirus... | ['3T3 Cells', 'Animals', 'Binding, Competitive', 'DNA, Viral', 'Genetic Vectors', 'HeLa Cells', 'Humans', 'Mice', 'Polymerase Chain Reaction', 'Proviruses', 'Retroviridae', 'Titrimetry'] | 8,854,093 | [['A11.251.210.100', 'A11.329.228.100'], ['B01.050'], ['E05.196.080', 'G02.111.084', 'G02.111.570.120.309'], ['D13.444.308.568'], ['G05.360.337'], ['A11.251.210.190.400', 'A11.251.860.180.400', 'A11.436.340'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B01.050.150.900.649.313.992.635.505.500'], ['E05.393.620.50... | ['Anatomy [A]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Paracellular diffusion in Caco-2 cell monolayers: effect of perturbation on the transport of hydrophilic compounds that vary in charge and size. | We applied the principles of molecular-size-restricted diffusion within a negative electrostatic field of force to follow the changes in the aqueous pore radius of tight junctions (TJs) induced by perturbants and the accompanying influence on the permeation of neutral (urea and mannitol), cationic (methylamine and aten... | ['Atenolol', 'Biological Transport', 'Caco-2 Cells', 'Cell Membrane Permeability', 'Chelating Agents', 'Chemical Phenomena', 'Chemistry, Physical', 'Diffusion', 'Drug Interactions', 'Egtazic Acid', 'Formates', 'Humans', 'Lactic Acid', 'Mannitol', 'Methylamines', 'Palmitoylcarnitine', 'Solutions', 'Structure-Activity Re... | 9,344,165 | [['D02.033.100.624.698.070', 'D02.033.755.624.698.070', 'D02.092.063.624.698.070'], ['G03.143'], ['A11.251.210.190.160', 'A11.251.860.180.160', 'A11.436.140'], ['G03.143.335', 'G04.175'], ['D27.505.519.914.500', 'D27.720.832.500'], ['G02'], ['H01.181.529'], ['G01.202', 'G02.196'], ['G07.690.773.968'], ['D02.092.782.258... | ['Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Anatomy [A]', 'Disciplines and Occupations [H]', 'Organisms [B]'] | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Comparative study on the effect of reamed and nonreamed intramedullary nails on treating open tibial fractures. | OBJECTIVE: To compare the clinical effect of reamed and nonreamed intramedullary interlocking nails on treating open tibial fractures.METHODS: From February 2002 to February 2004, 92 cases of open tibial fractures (86 patients) were treated with intramedullary interlocking nails. Of the 86 patients, 65 were male and 21... | ['Adolescent', 'Adult', 'Aged', 'Bone Nails', 'Female', 'Follow-Up Studies', 'Fracture Fixation, Intramedullary', 'Fractures, Open', 'Humans', 'Male', 'Middle Aged', 'Tibial Fractures'] | 16,457,440 | [['M01.060.057'], ['M01.060.116'], ['M01.060.116.100'], ['E07.695.370.249', 'E07.858.442.660.460.249', 'E07.858.690.725.460.249'], ['E05.318.372.500.750.249', 'N05.715.360.330.500.750.350', 'N06.850.520.450.500.750.350'], ['E04.555.300.300.300'], ['C26.404.311'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.0... | ['Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Diseases [C]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
[Contribution of air computerized tomography of the joint in the assessment of algo-dysfunctional syndromes of the mastication system]. | The prospective study of evaluation temporomandibular dysfunction by air computerized tomography of the joint are reported. The authors propose a new injection technique of both articular compartments by CT Scan location. With thin sagittal computed tomography sections, closed mouth and open mouth position, this study ... | ['Air', 'Humans', 'Joint Dislocations', 'Prospective Studies', 'Temporomandibular Joint', 'Temporomandibular Joint Dysfunction Syndrome', 'Tomography, X-Ray Computed'] | 2,309,085 | [['G16.500.275.063.150', 'N06.230.300.100.150'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C05.550.518', 'C26.289'], ['E05.318.372.500.750.625', 'N05.715.360.330.500.750.650', 'N06.850.520.450.500.750.650'], ['A02.835.583.861', 'A14.907'], ['C05.500.607.221.897.897', 'C05.550.905.905', 'C05.651.243.897.897', '... | ['Phenomena and Processes [G]', 'Health Care [N]', 'Organisms [B]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Protective effect of syringic acid on kidney ischemia-reperfusion injury. | The objective of the present study was to determine whether preischemic administration of syringic acid (SA) would attenuate renal ischemia-reperfusion injury (IRI). Rats were divided into three groups: Sham group; IR group; and IR + SA group. The effects of SA were examined using biochemical parameters including serum... | ['Animals', 'Gallic Acid', 'Kidney', 'Male', 'Rats', 'Rats, Wistar', 'Reperfusion Injury'] | 26,915,396 | [['B01.050'], ['D02.241.223.100.300.200', 'D02.241.511.390.200', 'D02.455.426.559.389.127.281.200', 'D02.455.426.559.389.657.410.200'], ['A05.810.453'], ['B01.050.150.900.649.313.992.635.505.700'], ['B01.050.150.900.649.313.992.635.505.700.900'], ['C14.907.725', 'C23.550.767.877']] | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Anatomy [A]', 'Diseases [C]'] | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Lower lip reconstruction: introduction of a new procedure using a functioning gracilis muscle free flap. | BACKGROUND: Subtotal and total reconstruction of the lower lip is a challenge for the plastic surgeon: this lip mainly contributes to the continence function of the oral sphincter. Fasciocutaneous free flaps and local flaps are better suited to the skin laxity of elderly patients; furthermore, larger defects extending ... | ['Adult', 'Female', 'Humans', 'Lip', 'Lip Neoplasms', 'Male', 'Reconstructive Surgical Procedures', 'Surgical Flaps'] | 17,415,241 | [['M01.060.116'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A01.456.505.631.515', 'A14.549.336'], ['C04.588.443.591.550', 'C07.465.409.640', 'C07.465.530.550'], ['E04.680'], ['A10.850.710', 'E07.862.710']] | ['Named Groups [M]', 'Organisms [B]', 'Anatomy [A]', 'Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Contralateral muscle fatigue in human quadriceps muscle: evidence for a centrally mediated fatigue response and cross-over effect. | The purpose of this investigation was to examine the effects of voluntary muscular fatigue in one lower limb and determine whether a 'cross-over' of fatigue is evident in the contralateral limb. Twenty-eight subjects (13 males and 15 females) performed a series of voluntary and evoked isometric contractions of both the... | ['Action Potentials', 'Adult', 'Central Nervous System', 'Electromyography', 'Exercise', 'Female', 'Humans', 'Male', 'Muscle Fatigue', 'Quadriceps Muscle'] | 16,365,782 | [['G04.580.100', 'G07.265.675.100', 'G11.561.570.100'], ['M01.060.116'], ['A08.186'], ['E01.370.405.255', 'E01.370.530.255'], ['G11.427.410.698.277', 'I03.350'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['G11.427.550'], ['A02.633.567.850']] | ['Phenomena and Processes [G]', 'Named Groups [M]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Organisms [B]'] | 1 | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 |
Glycerol and environmental factors: effects on 1,3-propanediol production and NAD(+) regeneration in Lactobacillus panis PM1. | AIMS: This study was conducted to understand the influences of fermentation factors in NADH recycling and mechanisms of 1,3-propanediol (1,3-PDO) production in Lactobacillus panis PM1.METHODS AND RESULTS: We conducted metabolite analyses, qRT-PCR of the glycerol reductive pathway [glycerol dehydratase (DhaB) and 1,3-PD... | ['Fermentation', 'Glycerol', 'Hydro-Lyases', 'Hydrogen-Ion Concentration', 'Lactobacillus', 'NAD', 'Propylene Glycols', 'Temperature'] | 23,795,775 | [['G02.111.158.249', 'G03.191.249'], ['D02.033.800.875.500', 'D09.853.875.500'], ['D08.811.520.241.300'], ['G02.300'], ['B03.353.750.450.475', 'B03.510.460.400.410.475.475', 'B03.510.550.450.475'], ['D03.633.100.759.646.138.694', 'D08.211.589', 'D13.695.667.138.694', 'D13.695.827.068.694'], ['D02.033.455.706'], ['G01.9... | ['Phenomena and Processes [G]', 'Chemicals and Drugs [D]', 'Organisms [B]', 'Health Care [N]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
In vitro osteoblast-like cell proliferation on nano-hydroxyapatite coatings with different morphologies on a titanium-niobium shape memory alloy. | The morphology of nanomaterials significantly affects their physical, chemical, and biological properties. In the present study, nano-hydroxyapatite coatings with different morphologies were produced on the surface of a titanium-niobium shape memory alloy via a hydrothermal process. The effect of the nano-hydroxyapatit... | ['Alloys', 'Animals', 'Cell Line', 'Cell Proliferation', 'Coated Materials, Biocompatible', 'Durapatite', 'Ethylene Glycol', 'Humans', 'Materials Testing', 'Microscopy, Electron, Scanning', 'Nanostructures', 'Niobium', 'Osteoblasts', 'Surface Properties', 'Titanium', 'Water', 'X-Ray Diffraction'] | 20,725,978 | [['D01.552.033', 'D25.058', 'J01.637.051.058'], ['B01.050'], ['A11.251.210'], ['G04.161.750', 'G07.345.249.410.750'], ['D25.130.420', 'J01.637.051.130.420'], ['D01.029.260.700.675.374.075.025.300.150', 'D01.146.360.050.300.200', 'D01.578.122.477.300', 'D01.695.625.675.650.075.025.300.150'], ['D02.033.455.250.268'], ['B... | ['Chemicals and Drugs [D]', 'Technology, Industry, and Agriculture [J]', 'Organisms [B]', 'Anatomy [A]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
A prospective population-based management program including primary surgery and postoperative risk assessment by means of DNA ploidy and histopathology. Adjuvant radiotherapy is not necessary for the majority of patients with FIGO stage I-II endometrial cancer. | A management program for FIGO stage I-II nonserous, nonclear-cell adenocarcinomas was evaluated. Histopathology and DNA ploidy were used to estimate postoperatively the risk of progression or death of disease and to tailor treatment. The patient material was a population-based consecutive cohort of all women with endom... | ['Adenocarcinoma', 'Adult', 'Aged', 'Aged, 80 and over', 'Combined Modality Therapy', 'Disease Progression', 'Disease-Free Survival', 'Endometrial Neoplasms', 'Female', 'Humans', 'Middle Aged', 'Neoplasm Metastasis', 'Neoplasm Staging', 'Ploidies', 'Prospective Studies', 'Radiotherapy, Adjuvant', 'Registries', 'Risk Fa... | 15,228,416 | [['C04.557.470.200.025'], ['M01.060.116'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['E02.186'], ['C23.550.291.656'], ['E01.789.800.190', 'E05.318.740.998.300', 'N04.761.559.590.800.190', 'N05.715.360.575.575.800.190', 'N05.715.360.750.795.300', 'N06.850.520.830.998.300'], ['C04.588.945.418.948.585', 'C13.351.500.... | ['Diseases [C]', 'Named Groups [M]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Phenomena and Processes [G]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
Surgery at the BEST Medical Center-Clyde's Adventures in BEST Land: Down the Rabbit Hole. | Dr. Ida Lystic is an assistant professor in the Division of Gastroenterology at the Byron Edwards & Samuel Thompson (BEST) Medical Center. Before becoming one of the BEST doctors, she completed her fellowship training at the Owen T. Henry and Eugene Rutherford (OTHER) Medical Center and her MD degree at the prestigious... | ['Academic Medical Centers', 'Atrial Fibrillation', 'Cerebrospinal Fluid Leak', 'Hospital Rapid Response Team', 'Humans', 'Lumbar Vertebrae', 'Male', 'Middle Aged', 'Myocardial Infarction', 'Postoperative Complications', 'Quality of Health Care', 'Spinal Stenosis'] | 30,047,440 | [['N02.278.020'], ['C14.280.067.198', 'C23.550.073.198'], ['C10.597.114', 'C10.900.300.109', 'C23.888.592.114', 'C26.915.300.225'], ['N04.590.715.550'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['A02.835.232.834.519'], ['M01.060.116.630'], ['C14.280.647.500', 'C14.907.585.500', 'C23.550.513.355.750', 'C23.550.7... | ['Health Care [N]', 'Diseases [C]', 'Organisms [B]', 'Anatomy [A]', 'Named Groups [M]'] | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 |
Bilateral giant cell tumour of the distal radius: a case report. | A case of bilateral distal radius giant cell tumour of bone is reported. Each lesion appears to have arisen de novo rather than as a metastasis. | ['Adult', 'Bone Neoplasms', 'Female', 'Giant Cell Tumors', 'Humans', 'Radiography', 'Radius'] | 2,794,721 | [['M01.060.116'], ['C04.588.149', 'C05.116.231'], ['C04.557.450.565.380'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E01.370.350.700'], ['A02.835.232.087.090.700']] | ['Named Groups [M]', 'Diseases [C]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
[Partial atrioventricular septal defect associated with right atrioventricular valve Ebstein's disease]. | The association of Ebstein's disease and atrioventricular septal defect is extremely rare with only 13 cases described in the literature and none in our country. We described a 15 year-old girl with echo and angiographic diagnosis confirmed by surgery. The non-identification of one of the lesions could impair planning ... | ['Abnormalities, Multiple', 'Adolescent', 'Ebstein Anomaly', 'Female', 'Heart Septal Defects, Ventricular', 'Humans'] | 9,497,527 | [['C16.131.077'], ['M01.060.057'], ['C14.240.400.395', 'C14.280.400.395', 'C16.131.240.400.395'], ['C14.240.400.560.540', 'C14.280.400.560.540', 'C16.131.240.400.560.540'], ['B01.050.150.900.649.313.988.400.112.400.400']] | ['Diseases [C]', 'Named Groups [M]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
Skin and soft-tissue infections caused by Aeromonas species. | This study investigated the clinical characteristics of patients with skin and soft-tissue infections (SSTIs) due to Aeromonas species. Patients with SSTIs caused by Aeromonas species during the period from January 2009 to December 2011 were identified from a computerized database of a regional hospital in southern Tai... | ['Adult', 'Aeromonas', 'Aged', 'Aged, 80 and over', 'Coinfection', 'Female', 'Gram-Negative Bacterial Infections', 'Hospitals', 'Humans', 'Male', 'Middle Aged', 'Prevalence', 'Skin Diseases, Bacterial', 'Soft Tissue Infections', 'Survival Analysis', 'Taiwan'] | 23,135,756 | [['M01.060.116'], ['B03.440.450.019.025'], ['M01.060.116.100'], ['M01.060.116.100.080'], ['C01.218'], ['C01.150.252.400'], ['N02.278.421'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.985.525.750', 'N01.224.935.597.750', 'N06.850.505.400.975.525.750', 'N06.850.520.308.985.525.750... | ['Named Groups [M]', 'Organisms [B]', 'Diseases [C]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
SG2-Type R2R3-MYB Transcription Factor MYB15 Controls Defense-Induced Lignification and Basal Immunity in Arabidopsis. | Lignification of cell wall appositions is a conserved basal defense mechanism in the plant innate immune response. However, the genetic pathway controlling defense-induced lignification remains unknown. Here, we demonstrate the Arabidopsis thaliana SG2-type R2R3-MYB transcription factor MYB15 as a regulator of defense-... | ['Arabidopsis', 'Arabidopsis Proteins', 'Flagellin', 'Gene Expression Regulation, Plant', 'Genes, Plant', 'Lignin', 'Phenols', 'Plant Immunity', 'Promoter Regions, Genetic', 'Protein Binding', 'Pseudomonas syringae', 'Scopoletin', 'Sequence Homology, Amino Acid', 'Solubility', 'Transcription Factors'] | 28,733,420 | [['B01.650.940.800.575.912.250.157.100'], ['D12.776.765.149'], ['D12.776.097.380'], ['G05.308.375'], ['G05.360.340.024.340.393', 'G05.360.340.365.500'], ['D05.750.078.562.180.515', 'D05.750.078.687', 'D20.538', 'D25.720.099.687', 'J01.637.051.720.099.687'], ['D02.455.426.559.389.657'], ['G12.450.800', 'G15.630'], ['G02... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Phenomena and Processes [G]', 'Technology, Industry, and Agriculture [J]'] | 0 | 1 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Thyroid hormone-induced changes in body temperature and metabolism during exercise in dogs. | Changes in serum total thyroxine concentration (TT4) and the effects of thyroxine (T4) and 3,5,3'-triiodothyronine (T3) injection on plasma free fatty acid (FFA) level and rectal temperature (Tre) responses were measured in six dogs at rest and during 1 h of submaximal treadmill exercise. At rest there were no increase... | ['Animals', 'Blood Proteins', 'Body Temperature', 'Dogs', 'Fatty Acids, Nonesterified', 'Hematocrit', 'Male', 'Osmolar Concentration', 'Oxygen Consumption', 'Physical Exertion', 'Plasma Volume', 'Thyroxine', 'Triiodothyronine'] | 1,163,655 | [['B01.050'], ['D12.776.124'], ['E01.370.600.875.374', 'G07.110'], ['B01.050.150.900.649.313.750.250.216.200'], ['D10.251.310'], ['E01.370.225.625.400', 'E05.200.625.400', 'G09.188.370.374'], ['G02.640'], ['G03.680'], ['G11.427.683'], ['G09.188.130.610', 'G09.330.380.092.610'], ['D06.472.931.812', 'D12.125.072.050.767'... | ['Organisms [B]', 'Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]'] | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Chromosomal localization and catalytic properties of the recombinant alpha subunit of human lymphocyte methionine adenosyltransferase. | Human lymphocyte methionine adenosyltransferase (HuLy MAT) consists of heterologous subunits alpha and beta. The cDNA sequence of the alpha subunit of HuLy MAT from Jurkat leukemic T cells was identical to that of the human kidney alpha subunit and highly homologous to the sequence of the extrahepatic MAT from other so... | ['Adult', 'Amino Acid Sequence', 'Animals', 'Base Sequence', 'Cell Line', 'Chromosome Banding', 'Chromosome Mapping', 'Chromosomes, Human, Pair 2', 'Cloning, Molecular', 'DNA Primers', 'Escherichia coli', 'Gene Library', 'Humans', 'Kidney', 'Liver', 'Lymphocytes', 'Macromolecular Substances', 'Methionine Adenosyltransf... | 7,665,609 | [['M01.060.116'], ['G02.111.570.060', 'L01.453.245.667.060'], ['B01.050'], ['G02.111.570.080', 'G05.360.080', 'L01.453.245.667.080'], ['A11.251.210'], ['E01.370.225.500.385.130', 'E01.370.225.500.620.670.130', 'E01.370.225.750.600.670.130', 'E05.200.500.385.130', 'E05.200.500.620.670.130', 'E05.200.750.600.670.130', 'E... | ['Named Groups [M]', 'Phenomena and Processes [G]', 'Information Science [L]', 'Organisms [B]', 'Anatomy [A]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Chemicals and Drugs [D]'] | 1 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 0 | 0 |
[Quality and value of expert assessment of disability with reference to evaluation of cardiovascular diseases]. | Because of the high frequency of diseases of heart and circulation a great number of physicians is concerned with experts opinions of them. There were 273 experts opinions from the rural and city district of Leipzig analysed in order to estimate quality and assertions force of experts opinions of invalidity with regard... | ['Coronary Disease', 'Disability Evaluation', 'Exercise Test', 'Expert Testimony', 'Germany', 'Humans', 'Hypertension', 'Rehabilitation, Vocational', 'Work Capacity Evaluation'] | 2,102,030 | [['C14.280.647.250', 'C14.907.585.250'], ['E01.370.400'], ['E01.370.370.380.250', 'E01.370.386.700.250', 'E05.333.250'], ['I01.880.604.583.232', 'N03.706.535.253'], ['Z01.542.315'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['C14.907.489'], ['E02.760.169.063.500.782', 'E02.831.782', 'N02.421.784.644'], ['E01.370... | ['Diseases [C]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Geographicals [Z]', 'Organisms [B]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 1 |
Prospective study of leptospirosis transmission in an urban slum community: role of poor environment in repeated exposures to the Leptospira agent. | BACKGROUND: Leptospirosis has emerged as an urban health problem as slum settlements have rapidly spread worldwide and created conditions for rat-borne transmission. Prospective studies have not been performed to determine the disease burden, identify risk factors for infection and provide information needed to guide i... | ['Adolescent', 'Adult', 'Brazil', 'Child', 'Child, Preschool', 'Female', 'Humans', 'Leptospira', 'Leptospirosis', 'Male', 'Middle Aged', 'Poverty Areas', 'Prospective Studies', 'Risk Factors', 'Social Conditions', 'Urban Health', 'Urban Population', 'Young Adult'] | 24,875,389 | [['M01.060.057'], ['M01.060.116'], ['Z01.107.757.176'], ['M01.060.406'], ['M01.060.406.448'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['B03.440.400.425.475.475', 'B03.851.475.475'], ['C01.150.252.400.794.511'], ['M01.060.116.630'], ['I01.880.853.996.535.550', 'N01.824.600.550'], ['E05.318.372.500.750.625', 'N0... | ['Named Groups [M]', 'Geographicals [Z]', 'Organisms [B]', 'Diseases [C]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]'] | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Oral contraceptives, breastfeeding and the risk of developing rheumatoid arthritis: results from the Swedish EIRA study. | OBJECTIVES: To study whether oral contraceptive (OC) use or breastfeeding (BF) influence the risk of rheumatoid arthritis (RA), stratifying the cases by presence/absence of anticitrullinated protein antibodies (ACPA), and whether these factors interact with known risk factors in the development of ACPA-positive RA.METH... | ['Adult', 'Arthritis, Rheumatoid', 'Autoantibodies', 'Breast Feeding', 'Case-Control Studies', 'Contraceptives, Oral', 'Female', 'Humans', 'Middle Aged', 'Odds Ratio', 'Peptides, Cyclic', 'Risk Factors', 'Smoking', 'Sweden', 'Time Factors', 'Young Adult'] | 28,818,831 | [['M01.060.116'], ['C05.550.114.154', 'C05.799.114', 'C17.300.775.099', 'C20.111.199'], ['D12.776.124.486.485.114.323', 'D12.776.124.790.651.114.323', 'D12.776.377.715.548.114.323'], ['F01.145.407.199', 'G07.203.650.195', 'G07.203.650.220.500.500', 'G07.203.650.353.199'], ['E05.318.372.500.500', 'N05.715.360.330.500.50... | ['Named Groups [M]', 'Diseases [C]', 'Chemicals and Drugs [D]', 'Psychiatry and Psychology [F]', 'Phenomena and Processes [G]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Health Care [N]', 'Organisms [B]', 'Geographicals [Z]'] | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
The outcome of an in vitro fertilization program in women with polycystic ovary syndrome. | The objective of this study was to examine the efficacy of D-triptorelin in the long protocol and follicle-stimulating hormone (FSH) in an IVF-embryo transfer program in a group of patients with polycystic ovary syndrome (PCOS) who had earlier failed to respond or did not conceive after clomiphene citrate (CC)/human me... | ['Chorionic Gonadotropin', 'Embryo Transfer', 'Female', 'Fertilization in Vitro', 'Follicle Stimulating Hormone', 'Humans', 'Ovulation Induction', 'Polycystic Ovary Syndrome', 'Pregnancy', 'Treatment Outcome', 'Triptorelin Pamoate'] | 9,272,422 | [['D06.472.699.322.326', 'D06.472.699.649.367', 'D12.644.548.726.367', 'D12.776.780.400'], ['E02.875.800.500', 'E05.820.800.500'], ['E02.875.800.750', 'E05.820.800.750'], ['D06.472.699.322.576.288', 'D06.472.699.631.525.343.288', 'D12.644.548.691.525.343.288'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['E02.875... | ['Chemicals and Drugs [D]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Health Care [N]'] | 0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 |
Genetic control of resistance to Coccidioides immitis: a single gene that is expressed in spleen cells determines resistance. | We have previously reported that inbred mice vary widely in their resistance to Coccidioides immitis peritonitis. To investigate the number of genes controlling resistance, (susceptible X resistant)F1 X susceptible backcross mice were tested for resistance to infection. A 1:1 ratio of resistant:susceptible offspring wa... | ['Animals', 'Coccidioides', 'Coccidioidomycosis', 'Female', 'Genes, Fungal', 'Immunity, Innate', 'Male', 'Mice', 'Mice, Inbred A', 'Mice, Inbred AKR', 'Mice, Inbred BALB C', 'Mice, Inbred C3H', 'Mice, Inbred C57BL', 'Mice, Inbred CBA', 'Mice, Inbred DBA', 'Peritonitis', 'Radiation Chimera', 'Spleen'] | 3,998,472 | [['B01.050'], ['B01.300.381.230'], ['C01.150.703.203'], ['G05.360.340.024.340.364.500', 'G05.360.340.358.024.500', 'G05.360.340.358.365.500'], ['G12.450.564'], ['B01.050.150.900.649.313.992.635.505.500'], ['B01.050.050.199.520.520.300', 'B01.050.150.900.649.313.992.635.505.500.400.300'], ['B01.050.050.199.520.520.318',... | ['Organisms [B]', 'Diseases [C]', 'Phenomena and Processes [G]', 'Anatomy [A]'] | 1 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Attitudes Toward Restricting the Sexual and Reproductive Rights of Women Living With HIV Infection in Yemen. | A considerable amount of research has demonstrated the pervasive and destructive power of discrimination against people living with HIV, which limits their full and equal participation in society. This study surveyed 613 young adults from Yemen about their attitudes toward the sexual and reproductive rights of women li... | ['Adolescent', 'Adult', 'Discrimination, Psychological', 'Female', 'HIV Infections', 'Health Knowledge, Attitudes, Practice', 'Humans', 'Male', 'Middle Aged', 'Population Surveillance', 'Pregnancy', 'Prejudice', 'Reproductive Rights', 'Sexual Behavior', 'Social Stigma', 'Socioeconomic Factors', 'Surveys and Questionnai... | 26,613,828 | [['M01.060.057'], ['M01.060.116'], ['F02.463.593.257'], ['C01.221.250.875', 'C01.221.812.640.400', 'C01.778.640.400', 'C01.925.782.815.616.400', 'C01.925.813.400', 'C20.673.480'], ['F01.100.150.500', 'N05.300.150.410'], ['B01.050.150.900.649.313.988.400.112.400.400'], ['M01.060.116.630'], ['E05.318.308.980.438.700', 'N... | ['Named Groups [M]', 'Psychiatry and Psychology [F]', 'Diseases [C]', 'Health Care [N]', 'Organisms [B]', 'Analytical, Diagnostic and Therapeutic Techniques, and Equipment [E]', 'Phenomena and Processes [G]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Geographicals [Z]'] | 0 | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 | 1 | 1 |
Content and communication: how can peer review provide helpful feedback about the writing? | BACKGROUND: Peer review is assumed to improve the quality of research reports as tools for scientific communication, yet strong evidence that this outcome is obtained consistently has been elusive. Failure to distinguish between aspects of discipline-specific content and aspects of the writing or use of language may ac... | ['Communication', 'Peer Review, Research', 'Periodicals as Topic', 'Writing'] | 18,237,378 | [['F01.145.209', 'L01.143'], ['F01.829.316.549.700', 'H01.770.644.487', 'I01.880.604.640.700', 'L01.143.865.750', 'L01.737.640', 'N03.706.700.700'], ['L01.178.682.829.678'], ['L01.559.423.906']] | ['Psychiatry and Psychology [F]', 'Information Science [L]', 'Disciplines and Occupations [H]', 'Anthropology, Education, Sociology, and Social Phenomena [I]', 'Health Care [N]'] | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
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