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Synonyms of Postmoem staining : 1) Livor Mois 2) Lividity 3) Hypostasis 4) Vibices 5) Cadaveric lividity 6) Suggilation
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Ans. (b) AlkaliRef.: The Essentials of FSM by K.S. Narayan Reddy 31st ed. / 499* Maximum damage to the esophagus is caused by ingestion of alkali as compared to acid.* Alkali causes Liquifactive necrosis which is more damaging than coagulative necrosis caused by acid.* Liquifactive necrosis is caused by hydrolytic enzy...
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Ans. is 'a' i.e., Lips Fordyce spots (Fordyce granules or Fordyce disease)* Fordyce's spot represents ectopic sebaceous glands on lips (most common site) and oral mucosa. They may also appear on vulva and penis, where they are called Tyson's gland, i.e., ectopic sebaceous gland at penis (prepuce) and vulva is called ty...
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The treatment for choledochal cyst is complete excision with Roux-en-Y hepaticojejunostomy. The duodenal end of the bile duct should be oversewn without injury to the anomalous entry of the pancreatic duct, limiting the amount of residual biliary tissue at risk for malignancy. Side-to-side choledochoduodenostomy is not...
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Ans. is 'c' i.e., Pantoprazole o Pantaprazole is more acid stable and has higher oral bioavailability. It is also available for i.v. administration; paicularly employed in bleeding peptic ulcer and for prophylaxis of acute stress ulcers.
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Ans. is 'b' i.e., Griseofulvin o Contraceptive failure may occur if the following drugs are given concurrently :(a)Enzyme inducer -Enhances the metabolism of estrogen & progesterone.1. Phenytoin3. Carbamazepine5. Primidone2. Phenobarbitone4. Rifampicin6. Griseofulvin(b)Suppression of intestinal microflora - | enterohep...
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The membrane proteins are classified into two categories: Integral proteins or intrinsic membrane proteins Peripheral proteins or extrinsic membrane proteins. Integral proteins are not only closely associated with the lipid bilayer but also tightly bound to the cell membrane.
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GVHD occurs when immunologically competent cells or their precursors are transplanted into immunologically crippled recipients, and the transferred cells recognize alloantigen's in the host and attack host tissues. It is seen most commonly in the setting of HSC transplantation but, rarely, may occur following transplan...
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Peroxisomes: Organelle where H2O2 is produced and destroyed. H2O2 generated from superoxide by superoxide dismutase (SOD). Catalase present in Peroxisomes catalyzes the decomposition of H2O2 to O2 and H2O. It is one of the active enzymes capable of degrading millions of H2O2 per sec. Refer robbins 9/e p9
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The final step in the subjective refraction is binocular balancing--a process sometimes known as 'equalizing the accommodative effo' or 'equalization of vision'. This allows both eyes to have the retinal image simultaneously in focus. Reference : A K KHURANA OPHTALMOLOGY, Edition4 ,Page-557
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Ans. is a, i.e. 3 monthsRef. Williams Obs. 24/e, p 142Fetal kidneys start producing urine at 12 weeks = 3 months.Initial rate of production of urine = 7-14 ml/day.At term it is = 27 ml/hr or 650 ml/day.
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Ans. (d) Retained stones are discovered after 2 years of cholecystectomy* Recurrent stone: discovered after 2 years after Cholecystectomy* Retained stone: discovered within 2 years after cholecystectomy
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After embryonic disc fusion, conjoint twin is formed.
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B i.e. PolylysineCodonAAAGGGCCCTTT/ UUUTranslation productLysinQGlycineProlinePhenylalanine
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Corpus delicti (Latin: corpus-main body or mass of the structure, delictus - offence or fault) means the essence of crime or the body of offence. It includes facts and elements of a criminal offence for example murder, road traffic accident, place of suicide etc. The main pa of corpus delicti is the establishment of th...
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Ans. c. Shotgun (Ref: Parikh 6/e p4.33; Reddy 33/e p210, 29/e p189)Choking is the constricting device present at the muzzle end of the shotgun.ChokeIt is constricting device at the muzzle end of shotgunQIt lessens the rate of spread of shot after it leaves the muzzleQ.A choke is the last few inches of a shot gunIt infl...
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• Critical pH value: 2.5 • Gastric pH of 2.5 or less with a gastric contents volume greater than 25 ml are critical values. • Maximum pulmonary damage is achieved at an aspirate pH value of 1.5.
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Ans. b. Both free and combined chlorineTest for chlorination of waterOrtho-toluidine test (OT)Ortho-toluidine Arsenite test (OTA)* Free (residual) chlorine* Free chlorine* Free and Combined chlorine* Combined chlorineOTA test is better than OT test as:Detects both free and combine water chlorine separately.Not affected...
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Histology of liver * The perisinusoidal space (or space of Disse) is a narrow gap between a plate of hepatocytes and a sinusoid. * The width of this perisinusoidal space is 0.2-0.5 micrometre. * Microvilli of hepatocytes, stellate cells, interstitial fluid and collagen fibres are the major constituents of this space. R...
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A neurologist, neurosurgeon, or intensivist generally performs the clinical brain death examination. Two examinations consistent with brain death 12 hours apa, or one examination consistent with brain death followed by a consistent confirmatory study generally is sufficient to declare brain death. Documentation of no b...
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Hypothalamus controls anterior pituitary hormones. Posterior pituitary hormones synthesize in hypothalamus.
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Noonan syndrome: Autosomal dominant, Normal karyotype MC gene involved is PTPN 11 - C/F : Sho stature webbed neck Antimongoloid slant eyes (Opposite of Down syndrome) Cubitus valgus Intellectual disability - Similarities and differences between Noonan syndrome and Turner syndrome
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Ans. B i.e., Glucose challenge testGlucosuria in pregnancy (without elevation of serum glucose) - Occurs due to decrease in renal threshold of glucose.Gestational diabetes - Diabetes/glucose intolerance diagnosed (first recognized) in pregnancy, in otherwise normal women.Type 1 /Type 2 diabetes in pregnancy - A known d...
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B i.e. Skilled movement
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Management of heart disease patient in 2nd stage: No maternal pushing and the tendency to delay in the second stage of labor is to be curtailed by forceps or ventouse under pudendal and/or perineal block anesthesia. Ventouse is preferable to forceps as it can be applied without putting the patient in lithotomy position...
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ANSWER: (C) SnakeREF: Jawetz Microbiology 24th Ed Ch. 13Diphtheria toxin is absorbed into the mucous membranes and causes destruction of epithelium and a superficial inflammatory response. The necrotic epithelium becomes embedded in exuding fibrin and red and white cells, so that a grayish "pseudomembrane" is formed--c...
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Pseudoahrosis of the tibia is usually seen associated with NF-1,a false joint between knee and ankle. Sphenoid wing dysplasia is also seen in NF-1. Acoustic Neuromas/Schwannomas are seen with NF-2. Multifocal haemangioblastomas are associated with VHL. Powine stain,leptomeningeal vascular malformations and Tram Track a...
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Ans. (a) Caesarean sectionRef : D.C. Dutta 8th ed. / 290-92; William's 23rd ed. Chapter 35.* Placenta previa-placenta located at LUS.* One of the most commoncause of APH.* In case of centrally located placenta previa -mode of delivery is always CS.Management of placenta previa depends on its type- 4 typesIndication for...
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According to ADA specification #1 for amalgam, the acceptable dimensional change is -20 to +20 micron/cm. Reference: Marzouk Operative dentistry, pg-108
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Ans : A (W.Bancrofti) Hydrocele (genital involvement) is only feature of Bancroftian filariasis (W.Bancrofti) not of (rarely) Brugian fila riasis( B. malayi& B.Timori)"In chronic Bancroftian filariasis. the main clinical features are hydrocele; elephantiasis & chyluria. The Brugian filariasis isgenerally similar to Ban...
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Ref-harrison 18/e p697 N-acetylcycteine used for Paracetamol poisoning whereas slow intravenous infusion and chloride diersis with amifostine can limit cisplatin induced nephrotoxicity
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Breakdown of phospholipids cause the release of phospholipase A2 from the cell membrane Coicosteroid helps in induction of lipocoins in macrophages. Lipocoins inhibits phospholipase A2. This lead to decreased production of prostaglandins, Leukotriens.Thus pro inflammatory mediators are reduced. (REF.Essential of medica...
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Gemcitabine 1s DOC for palliative care.
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Floating is due to putrefactive gases (not due to respiratory tract gases).
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Ans. All A, B and C
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Increase beta HCG in urine
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Ans: a (Hair) Ref: Reddy, 27th ed, p. 84Trichology is the study of hair.NoteThanatology: Study of death in all aspects.Cheiloscopy: Study of lip markings for identification.Poroscopy: Study of microscopic pores present in the ridges of fingers.Dactylography: Study of finger prints.
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Horner syndrome is a sign of stellate ganglion block (miosis, enopthalmos,ptosis, anhydrosis and absence of cliospinal reflex
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Ans. is a i.e. Normal
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. Ans. d. VasodilationAngiotensin II causes vasoconstriction (most potent or - 4-S times more than noradrenaline on weight basis)."Cotonic motility is minimal in fasting period. Eating stimulates colonic contractions. Fat component of meal is major stimulus to colonic contractions. Protein ingestion inhibits colonic co...
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Ans. is 'b' C5-C6 Moro's reflex is a neonatal reflex which develops by 28th wk of gestation and disappears by 12 wks of age.Moro reflex is obtained by placing the infant in semi-upright position, then the head is momentarily allowed to fall backward with immediate re-support by the examiner's hand.The child symmetrical...
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reinforcement is a method of behavioral therapy there are various types of reinforcement namely positive reinforcement namely positive reinforcement, negative reinforcement and punishment psychonalysis is a type of psychotherapy which was introduced by FREUD Abreaction is one of the impoant step in psychoanalysis hynoa...
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Ans. is 'd' ie Hepatitis (Ref. Sabiston, 18/e pl515 (17/e, p 1561, 16/e, p 1056); Maingot's 10/e, p 300)Hemobilia is defined as bleeding into the biliary tree from an abnormal communication between a blood vessel and bile duct.Causes of hemobilia:Trauma (most common)iatrogenic trauma is the most common cause(includes i...
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Remittent Fever is a type or pattern of fever in which temperature does not touch the baseline and remains above normal throughout the day. Daily variation in temperature is more than 1degC in 24 hours, which is also the main difference as compared to continuous fever.Fever due to most infectious diseases is remittent....
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The corneal stroma is a mesenchymal tissue, derived from the periocular neural crest, is the thickest layer of the cornea, and is 'sandwiched' between the epithelium and the inner endothelium. The stroma is composed of organized collagen, mainly type I and type V collagen fibers, which maintain transparency. Keratocyte...
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This is used in the conservative management of ectopic due to its primary action of being and antiprogestin.
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The degree of darkening or opacity of an exposed film is referred to as optical density. The optical density of an area of an X-ray film can be measured as follows:
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Cricothyroid and internal pa of thyroarytenoid (vocalis) together constitute tensors of vocal cord. Intrinsic muscles acting on vocal cords: * Abductors: Posterior cricoarytenoid * Adductors: Lateral cricoarytenoid, Interarytenoid (transverse arytenoid), Thyroarytenoid (external pa) * Tensors: Cricothyroid, Vocalis (in...
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Juvenile myoclonic epilepsy is an epilepsy syndrome. Epilepsy syndromes are disorders in which epilepsy is a predominant feature and there is sufficient evidence to suggest a common underlying mechanism. Juvenile Myoclonic Epilepsy It is characterized by: Appearance in early adolescence Bilateral myoclonic jerks that ...
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Ref: Textbook of forensic medicine and toxicology( V.V.Pillay)17th edition page no.388 As per sec.375IPC any unlawful sexual intercourse by man with a woman with or without her consent when she is under 18years of age. And also coitus between man and his wife amounts to rape if the wife is less than 15 years of age,bec...
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Ans. is 'd' i.e., Hypercalcemia
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Refractive index: It is the ratio of sine of angle of incidence to the sine of angle of refraction. The refractive index of, Cornea: 1.37 Aqueous humour: 1.33 Crystalline lens: 1.42 Vitreous humour: 1.33 Also know: The total dioptric power of the eye is about +60 D out of which about +44 D is contributed by cornea and ...
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Tooth replacement prosthesis properties: Duplicate in the replacement to natural (Gold standard) Appearance (socailly acceptable) Function (comfortable & stable) Maintenance (throughout their serviceable lifetime on reasonable cost)
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Others : Lipoma. Oil cyst.
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ANSWER: (A) Heat strokeREF: Parikh 6th edition page 3.81"Heat stroke is due to impairment in body's heat regulatory mechanism caused by failure of cutaneous circulation and sweating following prolonged exposures to hot humid conditions"
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Cvek pulpotomy or partial pulpotomy Cvek has shown that, in exposures resulting from traumatic exposures, pulpal changes are characterized by a proliferative response, with inflammation extending only a few millimetres into the pulp.  When the hyperplastic tissue is removed, healthy pulp is seen. In cases with carious...
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Ans. (D) Carbapenems(Ref: Katzung 10/e p739)Carbapenems like imipenem are the only beta lactams reliably efficacious against ESBL producing bacteria.
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A wide variety of autoantibodies can be seen in systemic lupus erythematosus, including all of those listed. However, high titers of anti-double-stranded DNA and anti-Sm (not listed above) are considered to be the most specific for systemic lupus erythematosus. MUST KNOW: Anti-Jo-1 is associated with inflammatory myopa...
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Cervical intraepithelial neoplasia (CIN) is associated with human papilloma virus (HPV) infection, paicularly types 16 or 18. These papillomaviruses produce E6 and E7 proteins, which induce the expression of cellular p53 and p110Rb oncogenes, respectively. EBNA proteins are produced by the Epstein-Barr virus and are as...
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First cervical vertebra is known as Atlas. Second cervical vertebra is known as Axis. Special joint between Atlas, Axis and Occipital bone: Atlanto-Occipital joint: It is a synovial joint - ellipsoid type. Allows flexion and extension of head on neck (as like nodding up and down). Atlanto-Axial joint: It is a pivo...
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Gravida describes the total number of confirmed pregnancies that a woman has had, regardless of the outcome. Parity is defined as the number of bihs that a woman has had after 20 weeks gestation. The number of fetuses does not determine the parity. Twin pregnancy carried to ble gestational age is counted as 1 parity an...
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Brachioradialis - flexes forearm at elbow joint; rotates forearm to the mid prone position from supine or prone positions. Ref : B D Chaurasia's Human Anatomy , seventh edition , volume 1 , pg. no., 138
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Ans. is 'c' i.e., ACE inhibitors o Spironolactone is a potassium sparing diuretic, therefore, it can cause hyperkalemia decreasing the potassium diuresis.o ACE inhibitors can also cause hyperkalemia by inhibiting the production of angiotensin I, an inmmediate precursor of angiotensin II. Angiotensin causes excretion of...
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Guanethidine (10%) eye drops is useful in decreasing lid retraction in Thyrotoxic ophthalmopathy. It is an adrenergic neuron blocker which acts by inhibiting the release of noradrenaline in response to nerve stimulation.
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Most common type of TAPVC is supracardiac type,where 2 pulmonary vein join to form common pulmonary vein that may drains to left innominate vein or right superior venacava. Classification of TAPVC : Darling&;s classification (1957) is the most popular. 1. Type I-Supracardiac connections : 45% of TAPVC patients.The comm...
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Ans. (d) All of the aboveRef. Katzung 9th ed. /1028* Vitamin D has been used in treating renal osteodystrophy* In mild forms of malabsorption, vitamin D should suffice to raise serum levels of 25(OH) D into the normal range. Many patients with severe disease do not respond to vitamin D.* Calcitriol and Calcifediol have...
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c. Crohn's disease(Ref: Nelson's 20/e p 1819, Ghai 8/e p 304)Blood in stools, abdominal pain and systemic features like fever and weight loss for months is suggestive of Inflammatory bowel disease.
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Ans BHere the doubt is between Radiographs and USG. But in CNS tumours radiographs can show many direct and indirect signs like calcification, bone erosion, hyperostosis, widening of various intracranial foramina, features of raised ICT. But ultrasound simply cannot penetrate the skull and is useful only in children wh...
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Branchial cyst • It develops from persistence of precervical sinus, a small depression deep to the second arch that normally disappears during development. • According to Illingworth's theory, inclusion of ectopic parotid epithelium in the upper deep cervical lymph nodes leads to branchial cyst formation. • Though cong...
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Ans. is 'a' i.e., Positive chargeThe filtration surface is a three-layered structure : - i) Glomerular capillary endothelium; ii) The basement membrane (Basal lamina); and iii) Visceral epithelium of Bowman's capsule with their foot process (Podocytes).However, even the three layers put together do not provide an adequ...
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Ans. is 'b' i.e., True negative Sensitivity* It is the ability of a test to identify correctly all those who have the disease, i.e., true positive.Specificity* It is the ability of a test to identify correctly those who do not have the disease i.e., true negative
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Ans. is 'a' i.e., Defence attitude
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Ans. B. Glossopharyngeal nerveIn The pharynx, the sinus of Morgagni is the enclosed space between the upper border of the superior pharyngeal constrictor muscle, the base of the skull and the pharyngeal aponeurosis.Structures passing through this sinus are:1. Cartilaginous part of Auditory tube2. Levator veli palatini ...
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Ans. is c i.e. Vasectomy Vasectomy consists of dividing the vas deferens and disrupting the passage of sperms. It is done through a small incision in the scrotum under LA. There is no need to open the peritoneum.
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Neuropeptide Y (NPY) is a 36-amino acid peptide neurotransmitter found in the brain and autonomic nervous system. It augments the vasoconstrictor effects of noradrenergic neurons.A natural substance that acts on the brain to stimulate eating. When energy stores of the body are low (as in starving), orexigenic neurons a...
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Ans. d. (All of the above) (Ref. Guyton physiology 11th /pg. 337-338)MEDULLARY COLLECTING DUCT# Although the medullary collecting ducts reabsorb less than 10% of the filtered water and sodium, they are the final site for processing the urine and, therefore, play an extremely important role in determining the final urin...
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Ans. is 'c' i.e., Imipramine C/F of TCA (Tricyclic Anidepressant) poisoning Tricyclic antidepressant poisoning o TCAs act primarily by inhibiting serotonin and norepinephrine reuptake. It results in elevation of extracellular concentration of these neurotransmitters. o The toxic effects of TCAs are caused by four main ...
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Seminomas are associated with elevated beta hCG and placental alkaline phosphatase levels. Alfa fetoprotein levels are elevated in malignancies such as hepatoblastoma, hepatocellular carcinoma, germ cell tumor of ovary or testicle or colon cancer. Benign conditions causing elevated AFP levels are cirrhosis, hepatic nec...
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Ans. d. Dose independent pharmacokinetics (Ref: Harrison 19/e p2147,18/e p2749; Katzung 12/e p646; htt[://www.isdbweb. org/documents/file/1442_2pdf)Pharmacokinetics of rituximab (monoclonal antibodies) is dose dependent.'The rate of uptake and elimination of antibodies by target-mediated pathways is a function of dose ...
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Hypopigmented lesions in the centre of the forehead suggest chemical leucoderma with para tertiary butyl phenol. Which is a component of bindi. (Therefore hypopigmentation is on central head).
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POLICE INQUEST: Is conducted in suicide death due to animal, machinery death due to medical negligence, or ill-treatment, died under circumstances raising a reasonable suspicion MAGISTRATE'S INQUEST: death in police custody death in police firing death in prison, reformatories, Borstal school dowry death death in a psy...
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Ans. A. AnakinraAnakinra is IL-1 antagonist, leflunomide inhibit the growth of B cells. Adalimumab is monoclonal antibody which inhibit the TNF alpha. Sulfasalazine is DMARD.
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Thick ascending segment/limb.REABSORPTION IN THICK ASCENDING LIMB:Water reabsorption:Totally impermeable to water.Ascending segment also referred "Diluting" segment:Due to sodium & solute absorption without water.Resulting in tubular fluid dilution.Hence, Tubular fluid is hypotonic.Sodium, Potassium & Chloride reabsorp...
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Osmoreceptors are sensory receptors present in supraoptic nucleus. Hypothalamus regulates the water balance of the body through osmoreceptors by controlling water loss. The increased plasma osmolality stimulates the osmoreceptors in supraoptic nucleus. The stimulated neurons of supraoptic nucleus send impulses to the p...
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Psychotic features (delusions, hallucination) can occur in endogenous depression (not in reactive / neurotic depression) and occurs later in life (involutional depression). Major endogenous depression on top of dysthymia is called double depression → Psychotic features may occur.
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Ans. is 'a' i.e., Blunt trauma to eye o Berlin's edema (commotio retinae) is a common condition caused by blunt injury to the eye. It is characterized by decreased vision in the injured eye a few hours after the injury. Under examination the retina appears opaque and white in colour in the periphery but the blood vesse...
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Invasive cervical carcinoma is CDC stage 3 (AIDS)- Defining Oppounistics Illness in HIV infection. Invasive cervical cancer, is an (AIDS)-Defining Oppounistic illness in HIV infection among adults, adolescents, and chidren age >/= 6 years. CDC Stage 3 (AIDS)- Defining Oppounistic Illnesses in HIV infection. The centres...
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PUVA is used to treat extensive psoriasis and psoriasis that has not responded to other therapies. PUVA stands for psoralens plus UVA. Psoralens are used orally followed by exposure of lesions to measured amount of a type of ultraviolet light-UVA. Sho term side effects of PUVA therapy include tanning, pruritus, nausea,...
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The left spinal accessory nerve has been injured distal to the sternocleidomastoid muscle, resulting in paralysis of the trapezius, allowing the shoulder to droop and the superior angle to push out posteriorly. The sternocleidomastoid muscles are intact, as demonstrated by symmetry in strength in turning the head to th...
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Ans. is `b' i.e. HLA DR4
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Minoxidil is a potassium channel opener, useful as an antihypertensive drug. It can cause hirsutism in females and is used for the treatment of alopecia in males.
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Answer is A (Mitral Stenosis) Mid diastolic murmur with with presystolic accentuation is typically seen in mitral stenosis. Mitral stenosis is associated with a low-pitched rumbling diastolic murmur heard best at the apex. The murmur typically peaks during mid-diastole and again immediately before the, first hea sound ...
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Characteristic feature HCC Fibrolamellar variant of HCC Age 55 - 60 yrs 25-30yrs Sex Male>female Male = female HBV positivity 60-70% Rare Presence of Cirrhosis 90% Rare Tumor markers AFP PIVKA-2 NeurotensinVit B12 binding globulin Tumor Multicentric, bilobar & Invasive Well-Circumscribed Resectability Unresectable in 7...
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Enzymatic propey is seen with insulin receptorRef: KDT 6/e pg 43.
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Ans, B. Ether addictionEther addiction or etheromania is the addiction to inhalation or drinking of diethyl ether.
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The slide shows clusters of plasma cell., diagnostic of myeloma. Although multiple myeloma has been reported in some cases of first degree relatives and identical twins, no evidence for hereditary passage of disease exists. Radiation (A) has been shown to increase the risk for multiple myeloma. Farmers using herbicide...
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Ans. a. Angioneurotic edema (Ref: Logan Turner 10/e p161)Patient following peanut consumption presented with laryngeal edema, stridor, hoarseness of voice and swelling of tongue. Most likely diagnosis is angioneurotic edema.'Allergic angioedema: Most common type and usually affects those with some kind of food allergy....
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An initial spontaneous aboion, irrespective of the karyotype of sex of the child, does not change the risk of recurrence in the next pregnancy. The rate of aboion is commonly quoted as 15% of all known pregnancies. Recurrent pregnancy loss is seen in around 1 in 300 pregnancies. For patients with a history of RPL, the ...
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Premaliginant Lesions of Endometrium are:- Simple hyperplasia: Endometrium is thick. The glands are dilated and have outpouching and inva-ginations. They are crowded and have irregular outlines. The stroma is more dense and cellular. Complex hyperplasia: Endometrium is thicker. The gland are crowded and arranged back t...
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In pulmonary edema, as the pulmonary venous pressure increases, fluid leaks from the pulmonary capillaries into the adjacent interstitium. This interstitial pulmonary edema may be identified by peribronchial cuffing, indistinctness of the perivascular margins, perihilar haziness, and thickening of the interlobular sept...
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