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3D Trans-Urethral Ultrasound (TUUS) is a new technique for the diagnosis and treatment of prostate disease. TUUS provides real-time, high resolution images of the prostate. Because of the central location of urethra, the TUUS devices can use higher frequency than transreactal ultrasound (TRUS), since there is less tiss...
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Most children with an ASD are asymptomatic; the lesion is found during a routine examination. In older children, exercise intolerance can be noted if the lesion is of significant size. On examination, the pulses are normal, a right ventricular systolic lift at the left sternal border is palpable, and a fixed splitting ...
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FSGS - supar. Mbranous  nephropathy - M - PLA2.
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Long thoracic nerve innervates Serratus anterior. Serratus anterior originates from outer surface of upper 8 ribs and inserts onto inferior angle and medial border of scapula. Actions -        It rotates the scapula to help in overhead abduction. -        Steady the scapula to carry weight. -        Pushing of arm forw...
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Ans. A. Rise by 25%* During pregnancy glomerular filtration rate increases, which causes increased renal clearance of iodine.* Maternal serum iodine levels fall due to increased renal loss and also due to transplacental shift to the fetus. These cause hyperplasia of the gland.
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Sinus of Morgagni is a gap between the base of skull and the upper concave border of superior constrictor muscle. Structures passing through that are: Auditory tube, levator palati muscle, ascending palatine artery and palatine branch of the ascending pharyngeal artery.
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Adverse cardio vascular events due to congenital heart disease in pregnancy Arrhythmia (most common) Heart failure Thrombo embolism.
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Most precise test for imaging aortic aneurysm : CT scan 5-year risk of rupture for aneurysm :<5cm – 1 to 2% and > 5 cm-20 to 40% For asymptomatic abdominal aortic aneurysms, operation is indicated if the diameter is > 5.5 cm In elective surgery of AAA, the operative mortality rate is 1 to 2% whereas after acute rupture...
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The presence of pruritus with jaundice points to presence of cholestatic component. The presence of SAP increasing the credibility of diagnosis of obstetric cholestasis HELLP syndrome is ruled out as coagulation profile is normal Hepatorenal syndrome is ruled out as RFT is normal. The closest choice is viral hepatitis ...
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"The bony pelvis protects the urinary bladder very well. When the pelvis is fractured by blunt trauma, fragments from the fracture site may perforate the bladder. These perforations usually result in extra peritoneal rupture." — Smith's Urology
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DISACCHARIDASES DEFECIENCY Lactase defeciency diagnosis based on presence of more than .5%of reducing substance in the fresh stools acidic stools abnormal oral sugar tolerance test breath Hydrogen excretion of more than 11ppm following a loading dose of lactose enzyme assay on mucosal biopsies showing low levels of dis...
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Ans. (a) Vagus nerve(Ref Sabiston 20th Edition Page 794)* Standard RND (CRILE operation) removes nodal levels I through V and the sternocleidomastoid muscle, internal jugular vein, cranial nerve XI, cervical plexus, and submandibular gland.* Modified RND (Bocca Operation) preserves one or more of the three structures -...
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The posteromedial surface of the kidneys is embedded in fat and devoid of peritoneum. It is anterior to the diaphragm, the medial and lateral arcuate ligaments, psoas major, quadratus lumborum and the aponeurotic tendon of transversus abdominis, the subcostal vessels and subcostal, iliohypogastric, and ilioinguinal ner...
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Ans: d (Newborn..) Ref: Park, 19th ed, p. 213Even though malaria affect all ages, newborn infants have considerable resistance to infection with P. falciparum.This has been attributed to the high concentration of fetal haemoglobin during the first few months of life which suppress the development of P. falciparum.
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Ref harshmonhan 6/e p164-165 Sarcoidosis is a disease characterized by the growth of tiny collections of inflammatory cells (granulomas) in any pa of your body -- most commonly the lungs and lymph nodes. But it can also affect the eyes, skin, hea and other organs. The cause of sarcoidosis is unknown, but expes think it...
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Ans. is 'c' i.e., Glycine Glutathione Glutathione is a tripeptide made up of glutamate, cysteine and glycine (T-glutamyl-cysteinyl-glycine).Glutathione is present in all mammalian cells except neurons.The sulphydryl (-SH) group of cysteine residue is the reactive poion of glutathione which can undergo oxidation and red...
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Ans. is 'd' i.e., Propylthiouracil Propylthiouracil is the drug of choice for hyperthyroidism during pre2nancv.Antithyroid drugs in pregnancyPropylthiouracil and methimazole are both antithyroid drugs that cross the placenta and can lead to fetal goiter.Methimazole has been associated with "cutis aplasia ".Scalp defect...
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Ans. is 'c' i.e., Glutamine o Synthesis of asparagine from aspartate is catalyzed by asparagine synthetase,o Donor of amide group (containing nitrogen) in this reaction is glutamine.
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ANSWER:(B)KetamineREF: Textbook Of Forensic Medicine And Toxicology: Principles And Practice By Vij 4th ed page 566, style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif; margin: 0 0 0 8px; text-indent: 0; text-align: left">The Narcotic Drugs and Psychotropic Substances (NDPS) Act, 1985 was ...
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BRONCHOPULMONARY SEQUESTRATION Sequestration is the presence of lobes or segments of lung tissue which are not connected to the airway system. The blood supply of the sequestered area is not from the pulmonary arteries but from the aorta or its branches. Sequestration may be intralobar or extralobar.  Intralobar seques...
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Glucose transpoer 4 (GLUT 4) is found in two major insulin target tissues: skeletal muscle and adipose tissue. It is sequestered mainly within an intracellular compament of these cells and thus does not function as a glucose transpoer until insulin signaling causes translocation of GLUT 4 to the cell membrane, where it...
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Ans. Carotico-cavernous fistula
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Dentinal dysplasia Dentinal dysplasia is an inherited condition affecting both dentitions. It is divided into two types: Type I (radicular dentinal dysplasia) and Type II (coronal dentinal dysplasia). It occurs less frequently than dentinogenesis imperfecta. Clinical features Type I is the more frequent type. Teeth eru...
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THE GIVEN CONDITION IS OF SECOND DEGREE FROSTBITE INJURY Frostnip : It is a superficial freeze injury that causes no tissue loss. rewarming quickly reverses the symptoms. First-degree frostbite : It is characterized by paial skin freezing, erythema, edema, no blisters, and desquamation several days later. Second-degree...
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The Peptidyl transferase is an aminoacyltransferase as well as the primary enzymatic function of the ribosome, which forms peptide bonds between adjacent amino acids using tRNAs during the translation process of protein biosynthesis.In Prokaryotes, the 50S (23Scomponent) ribosome subunit contains the peptidyl transfera...
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Ans. (c) Somatostatin
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A. i.e. Deficit of attention; B. i.e. Autonomic instability; C. i.e. Altered sleep wake pattern
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The CRAZY PAVEMENT PATTERN is seen in pulmonary alveolar proteinosis and also can be observed in exogenous lipoid pneumonia, sarcoidosis, mucinous bronchoalveolar cell carcinoma and acute respiratory distress syndrome. Chest radiographs lack sensitivity for diagnosis of bronchiectasis, but the prsnce of TRAM TRACK LINE...
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Ans. is 'd' i.e., Insulin dependent Maturity onset diabetes of the young (MODY) o This is characterized by non-insulin dependent diabetes mellitusQ o The usual age of onset is 25 years or youngerQ o Patients are nonobese and their hyperglycemia is due to impaired glucose induced secretion of insulinQ. o It generally re...
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X- Linked Recessive Inheritance Hemophila A and B Duchenne muscular dystrophy G6PD deficiency Retinitis pigmentosa (most severe- less common form) Brutons Agammaglobulinemia Hunters syndrome Chronic Granulomatous disease Wiskott-Aldrich syndrome Diabetes insipidus Lesch-Nyhan syndrome Fragile X syndrome Dents disease K...
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Ans. is 'c' i.e., Regional ileitisThere is confusion between option c & d because macrophage and granuloma are seen in crohn's disease (Regional ileitis), while erythrophagocytosis is seen in typhoid fever.o Regional Ileitis or crohn's disease has the histological features of transmural inflammatory cell infiltrate con...
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Osmolarity of standard ORS solution is 245 mmol/l Reference: Ghai pediatrics eighth edition pg no 294
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Ans. C.4Trigeminal nerve has four nuclei - 3 sensory and 1 motor nucleus.The sensory nucleus is divided into three parts, from rostral to caudal (top to bottom):a. The mesencephalic nucleusb. The chief sensory nucleus (or "main sensory nucleus" or "principal nucleus")c. The spinal nucleus
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Trapezius originates from the occiput and inserts onto clavicle and scapula.
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Kata thermometer - measures cooling power of air Globe thermometer - measures radiant heat Sling Psychrometer - measures humidity Anemometer - measures air velocity Ref: Park, 21st Edition, Pages 688 to 691.
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Atropine poisoning is associated with hyperthermia (not hypothermia).
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In Marfan syndrome, a connective tissue disorder of autosomal dominant inheritance, the basic biochemical abnormality is a mutation affecting fibrillin. Mutations in the FBN1 gene are found in all patients with Marfan syndrome. Clinical features may include tall stature, long fingers, bilateral subluxation of lens, mit...
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The hallmark ultrastructural features of irreversible cell injury are: cell membrane defects, mitochondrial swelling and calcium accumulation and nulear chromatin clumping. Morphologic forms of reversible cell injury are :Cellular swellingFatty changeHyaline changeMucoid changeUltrastructural changes that occur in hydr...
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B i.e. Isoflurane
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Japanese encephalitis: Option 1: Humans, cattle, buffaloes, and pigs are the veebrate hosts. Option 2: Culex tritaeniorhynchus is a major vector but has predilection for cattle instead of humans or pigs. Since the cattle does not develop viremia, this does not contribute to the spread of the disease. The high cattle to...
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Agents Used for Treatment of Type 1 or Type 2 Diabetes Parenteral Amylin agonists Slow gastric emptying, glucagon Pramlintide 0.25-0.5 Reduce postprandial glycemia, weight loss Injection, nausea, risk of hypoglycemia with insulin Agents that also slow GI motility GLP-1 receptor agonists Insulin, glucagon, slow gastric ...
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The asterion is the point where the parietomastoid, occipitomastoid and lambdoid sutures meet. In infants the asterion is the site of the posterolateral or mastoid fontanelle,which closes at the end of the first year.
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The Red Cross is a non-political, non-official international humanitarian organization devoted to the service of mankind in peace and war. Founded by Henry Dunant.Park 23e pg: 925
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Ans. is 'b' i.e., Barbiturate poisoning o Elimination of poison from circulation can be by following methods :-Forced diuresis with or without alteration of urinary pH# Diuresis and ion trapping via alteration of urinary' pH may prevent the renal reabsorption of poisons that under go excretion by glomerular Alteration ...
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Farmer's lung is caused due to inhalation of mouldy hay or grain. Thermophillic actinomyeces, commonly Micropolyspora faeni is the common cause of farmer's lung. Ref: Park 21st edition, page 748. Chapter: Occupational health.
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Fetal ACTH acts on fetal adrenal gland causing release of DHEA and DHEA sulphate which are used by the placenta along with the other enzymes like Sulfatase ,Aromatase, 3 B hydroxysteroid dehydrogenase, 17 B hydroxysteroid dehydrogenase -Conveing into Estriol and Estardiol that help in triggering the labour. Ref: Willia...
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The ureteric bud is responsible for the development of the ureter, and thus an early splitting of the ureteric bud would result in formation of a second ureter on the ipsilateral side. Failure of the ureteric bud to form would cause a complete absence of the ureter, whereas failure of the ureteric bud to branch occurs ...
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Erythrocytes 120 days Platelets 8-9 days Neutrophils 5 days
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H2O2 -MPO - halide system is the most efficient bacterial system of neutrophils It is most efficient in Phagocytosis ref Robb ins 9/e p79
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Hypercalcemia never happens in malignant hypehermia. Clinical Manifestations of Malignant Hypehermia: Early Signs: Elevated end-tidal carbon dioxide Tachypnea and/or tachycardia Masseter spasm, if succinylcholine has been used Generalized muscle rigidity Mixed metabolic and respiratory acidosis Profuse sweating Mottlin...
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Pulmonary edema is one of the most serious consequences of left ventricular cardiac failure. When the left ventricle fails or when the mitral valve fails, left atrial pressure (LAP) may increase substantially. The resulting increase in pulmonary capillary pressure (Pc) forces excess fluid filtration through the pulmona...
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Exudation of fluid from venules and capillaries is a key component of the acute inflammatory process. Several mechanisms of increased vascular permeability have been proposed, including formation of interendothelial gaps by contraction of endothelium. This contraction can be caused by mediators such as histamine and le...
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Calcium needed in all the steps of the clotting EXCEPT: first two steps of intrinsic pathway under stimulatory effect of HMW kininogen & prekallikren
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Peripheral nerve involvement is a common in rheumatoid ahritis, with entrapment neuropathies at the carpal tunnel and tarsal tunnel making up most of the peripheral nerve injuries. Tarsal tunnel syndrome results from compression of the posterior tibial nerve as it passes under the medial malleolus in the medial aspect ...
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Ans. is a, i.e. It is always secondaryRef: Dutta Gynae 6th/ed, p387* Krukenberg tumor is generally a metastatic tumor to the ovary. But "Krukenberg tumor may be a primary tumor" - Ref: Dutta Gynae 6th/ed, p387* The most common primary sites from where metastases to the ovaries occur are gastrointestinal tract (pylorus,...
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ANS. A# Histology slides of gynecological malignanciesGranulosa cell tumor (coffee bean nuclei)Yolk sac tumorKrukenberg tumor (spindle cells)
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Potential symptom manifestations of a panic attack:Palpitations, pounding hea, or accelerated hea rateSweatingTrembling or shakingA sense of shoness of breath or smothering Feeling of chokingChest pain or discomfoNausea or abdominal distressFeeling dizzy, unsteady, lightheaded, or faintDerealization or depersonalizatio...
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Atropine is used in bradycardia as it increases hea rate by inhibiting m2 receptors on hea Ref: KDT 6th ed pg 106
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Ans. (d) Ventricular septal defect.* In the differential diagnosis, early-onset sepsis may be indistinguishable from RDS. In pneumonia manifested at birth, the chest roentgenogram may be identical to that for RDS. Maternal group B streptococcal colonization, organisms on Gram stain of gastric or tracheal aspirates or a...
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Ans. Dilatation of vessels
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D i.e. Keratoconus Corneal Pigmentation Condition Deposited Material Site Of Deposition Argyrosis Sliver nitrate (AgNO3) Brown discolouration of descement's membrane Fleischer ring Iron Epithelial iron deposits at the base of Keratoconus Chalcosis (Kayser Fleischer ring) Cu Grayish-green or golden brown discolouration ...
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Ans. is 'd' i.e., Mitochondrial membraneMitochondrial membrane permeabilization (MMP) a Mitochondria' membrane permeabilization (MMP) is the hallmark of apoptosis.o The release of proteins from the intermembrane space of mitochondria is one of the pivotal events in the apoptotic process,which can lead to the activation...
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Normally. the fluid in lymph is massaged by muscle contractions of the organs and contraction of aerioles and venules, with which they are often associated which increases the flow through lymph vessels lacking valves and smooth muscle Thus by massaging foot lymph flow can be increased Ref: Ganong's Review of Medical P...
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Ans. C: ASD Fixed splitting denotes absence of significant variation of the splitting interval with respiration, such that the separation of A2, and P2, remains unchanged during inspiration and expiration. Atrial septal defect, with either normal or high pulmonary vascular resistance, is the classic example of fixed sp...
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Phenolic compounds are bactericidal or bacteriostatic and some are fungicidal also. They act by denaturing proteins and disrupting cell membranes. They are effective in the presence of organic material and remain active on surfaces long after application.
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Ref:Parks 23rd edition pg 138 Validity (accuracy): refers to what extend the test accurately measures which it purpos to measure. has two components: sensitivity and specificity. note: Precision / repeatability / reliability: that is test must give consistent redults when repeated more than once on the same individual ...
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Adenovirus infection is often associated with pharyngitis, a follicular reaction and injection of the palpebral conjunctiva, and preauricular adenopathy (pharyngoconjunctival fever). Epidemics of adenoviral keratoconjunctivitis occur. Ref: Braverman R.S. (2012). Chapter 16. Eye. In W.W. Hay, Jr., M.J. Levin, R.R. Deter...
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Chancroid: caused by Hemophilus ducreyi Incubation period is 4 to 7 days Azithromycin is drug of choice Ref: Park 21st edition, page 305.
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Ans) a (Placenta praevia) Ref Williams 22nd editionCauses of APHa) Placental (70%)- Placenta previa (35%) - Abruption (35%)b) Extra placental (5%)- Cervical carcinoma - Carcinoma cervix - Varicose vein - Local traumac) Unexplained (25%) Stall Worthy sign- Low lying (post type)Dangerous placenta previa - TypeAt 20wks - ...
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Ans. b (Pernicious anemia) (Ref: Ganong's 22nd edition, p. 485; Harrison's 18th/ch. 105; 17th edition, p. 1869).# Parietal cell-containing gland is preferentially targeted in pernicious anemia, and achlorhydria results.# Achlorhydria, coupled with relative sparing of antral mucosa (site of G cells), leads to hypergastr...
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Nucleus of cerebellum (Lateral to medial ):Dentate, emboliform, globose &fastigial Cerebellar nuclei function Dentate working with lateral pa Co-ordinate movement of joint Fastigial working with central vermis Saccadic eye movement. Interposed nuclei (emboliform & globose) working with para vermal area Feedback mechani...
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• Vitamin K is produced by our gut flora. The gut of a New-born baby is sterile and hence no vitamin K is being produced. Moreover vitamin k is negligible in breast milk. In lieu of these factors all babies are susceptible to development of Hemorrhagic disease of New-born. • To prevent this from happening therefore, as...
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Respiratory alkalosis is one of the commonest causes of hypophosphatemia; it results from shift of phosphate from the extracellular to the intracellular space. Hypomagnesemia alone would increase phosphorus by decreasing parathormone effect. Hyperparathyroidism can decrease phosphorus but would cause hypercalcemia. Sev...
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Propofol produces quick induction(30 sec) and rapid recovery(4 min)from a single dose. Because of rapid recovery it is preferred for day cases. Thiopentone duration of action is 4-7min. And ketamine10-15min but amnesia lasts for 1-2 hours. From padmaja 4th edition Page no 194, 195, 196
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Galactose is a substrate for aldose reductase, forming galactitol, which accumulates in the lens of the eye, causing cataract. The condition is more severe if it is the result of a defect in the uridyl transferase since galactose-1-phosphate accumulates and depletes the liver of inorganic phosphateUltimately, liver fai...
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Epley`s maneuver is used in the treatment of Positional Veigo (BPPV)Dix Hallpike`s test is the diagnostic testOther exercises are: Semont`s maneuver, Brandt Darrof exercisesSurgeries: Singular neurectomy, Posterior canal occlusion, Labyrinthectomy, Vestibular nerve sectionRef: Hazarika; 3rd edition; Page no: 108
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Essential Pentosuria defect in Uronic Acid Pathway: Pentosuria is a condition where the sugar xylitol, a pentose, presents in the urine in unusually high concentrations. It was characterized as an inborn error of carbohydrate metabolism in 1908. It is associated with a deficiency of L-xylulose reductase, necessary for...
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Ans. a. Omeprazole reduces stomach acid Omeprazole reduces stomach acid secretion: This interaction is beneficial for patients suffering from GERD without having any associated complications. Rest three interactions has a bad impact on the normal healthy individuals. Methotrexate inhibiting folate Barbiturates decrease...
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Negril bodies are abundant un cerebellum&hippocampud REF:<\p> ANATHANARAYANAN MICROBIOLOGY NINTH EDITION PAGE.531
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Monocytes formed in the bone marrow are precursors of tissue macrophages. After an intravascular stay of 3 days, monocytes migrate from the blood into tissues. In the tissues, monocytes undergo differentiation into macrophages.
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In an incise wound the edges are clean cut and well defined usually with eveed margins. The edges may be inveed in the case of incised wounds on the scrotum. In case of incised wounds bridging tissue is not seen. Bridging tissue is suggestive of laceration and is caused a pa of the body being crushed or stretched beyon...
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Phenotype may be completely female
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Ref Harrison 19 th ed pg 1596 Results of multiple trials of different calcium antagonists have failed to establish a role for these agents in the treatment of most of the patients with MI .
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MDCT is the primary imaging technique used in evaluating patients suspected of having acute pancreatitis. CT useful for: Morphologic changes in the pancreas that allow confirmation of pancreatitis Assessment of the severity It is the only imaging study that predicts clinical outcome. Ref: ACR Appropriateness Criteria, ...
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Robbins and Cotran pathologic basis of disease South Asia edition. P53 gene located on sho arm of chromosome 17 is also termed TP53 because of molecular weight of 53kd for the protein. P53 inhibits the cyclins and CDKs and prevent the cell to enter G1 phase transiently. .
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Complication of shoulder dislocation: Banka's anterior glenoid labrum: anterior tear in anterior dislocation Hill Sach's at head of Humerus: posterolateral defect in anterior dislocation Reverse Hill Sach's - anteromedial defect in posterior dislocation Light bulb signis seen on AP radiographs in theposterior dislocati...
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Ans, is 'c' i.e., Cotransport of amino-acids with Na+ Transport mechanismExamplesSimple diffusionMovement of fats, oxygen, CO2 through lipid portion of membraneFacilitated diffusionMovement of glucose and some amino-acidsOsmosisMovement of water into and out of the cellPrimary active transportSecondary active transport...
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A i.e. Vernal conjunctivitis
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Ans: B. Volume 1.5 mL, count 15 million, morphology 4% progressive motility 32% (Ref Dutta 6/e p222)According to 2010 WHO criteria:Characteristics of normal semen analysis:Semen CharacteristicsWHO 1999WHO 2010Volume (ml)Greater or equal to 2 mlGreater or equal to 1.5 mlSperm countGreater or equal to 20 Greater or equal...
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The commonest site of origin in the nasopharynx is the fossa of Rosenmuller. Anterior spread causes blockage of choana and nasal cavity and inferior spread are towards oropharynx and hypopharynx, lateral spread involves parapharyngeal space and infratemporal fossa through the sinus of Morgagni, an upward spread is towa...
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Galagan formula for fluoride:  This is usually calculated by the formula given by Galagan and Vermillion in 1957. Ppm of F‾ = - 0.038 +0.0062 t (temperature in Fahrenheit) ‘E’ is the estimated daily water intake for children in ounces per pound of body weight. ‘t’ is the yearly mean of the daily maximum temperature in F...
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Answer- C. It is a reversible changeMetaplasia is an adaptive change in which one adult (mature) cell type is replaced by another adult (mature) cell.It is reversible.There is no pleomorphism, and cell polarity as well as cell & nuclear size are not altered.
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Types of correlation Scatter diagram Correlation coefficient Interpretation perfectly positive correlation Both lines haves a positive slope (at 45 degree each); superimposed r=+1 Rise in one variable leads to propoionate rise in other perfectly negative correlation Both lines have a negative slope (at 45 degree each);...
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Ans. is 'a' i.e., Reiter's syndrome
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Hemorrhagic disease of the new-born may be caused by a deficiency of vitamin K. Vitamin K is an important coagulation factor, which is necessary for the carboxylation and activation of prothrombin, as well as of clotting factors VII, IX, and X. Newborn infants frequently exhibit vitamin K deficiency because the vitamin...
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Generations of Amalgams
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Panoramic images are most useful clinically for diagnostic problems requiring broad coverage of the jaw. Common examples include evaluation  of trauma including jaw fractures, location of third molars, extensive dental or osseous disease, known or suspected large lesions, tooth development and eruption (especially in t...
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(5-FIucytosine) (715, 719-KDT) (761-KDT6th)FLUCYTOSINE (5-FC) - It is a pyrimidine antimetabolite which is inactive as such. It is taken up by fungal cells and converted into 5 fluorouracil and then to 5-fluorodeoxyuridylic acid which is an inhibitor of thymidylate synthesis* It is narrow spectrum fungistatic, active a...
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Ans. is 'c' i.e., Erotomania* Erotomania (Delusions of love): - False belief that another person is in love with one (commoner in woman). In one form, termed de clerambault sydrome, a woman (usually) believes that a man, frequently older and of higher status, is in love with her. Erotomania is seen in Schizophrenia, de...
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This child is suffering from Phenylketonuria. Here there is inability to conve phenylalanine to tyrosine due to phenylalanine hydroxylase deficiency. The decreased pigmentation in this condition is due to reduced melanin formation. The treatment is a diet low in phenylalanine with tyrosine supplementation. Delay in ini...
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