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When they first arrive at a high altitude, many individuals develop transient "mountain sickness." This syndrome devel- ops 8 to 24 h after arrival at altitude and lasts 4 to 8 d. It is characterized by headache, irritability, insomnia, breathlessness, and nausea and vomiting. Its cause is unsettled, but it appears to ...
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Conditions which lead to stasis, vascular injury, and hypercoagulability (Virchows triad) act as risk factors for DVT. Acquired risk factors include older age, cancer, surgery, trauma, immobilization, hormone replacement therapy, oral contraceptive use, pregnancy, neurologic disease, cardiac disease, and antiphospholip...
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Most common tumor of testis → Seminoma. Most common tumor of testis in childhood → yolk sac tumor (endodermal sinus tumor or infantile embryonal carcinoma).
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Ans. d (Fistula antefenestrum) (Ref. Bhargava ENT 6th ed., p 76; PL Dhingra, 3rd ed., p 114)# in otosclerosis, the oval window is involved in 85% of cases and the round window in 15%, respectively, with otosclerosis and conductive deafness.# Infact, the commonly involved site is the anterior oval window region {fistula...
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Familial adenomatous polyposis (FAP) is defined clinically by the presence of more than 100 colorectal adenomas but is also characterised by duodenal adenomas and multiple extraintestinal manifestationsmutations in the adenomatous polyposis coli (APC) gene on the sho arm of chromosome 5. FAP is inherited as an autosoma...
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CN3 lesion causes dilated pupil, down-and-out eye, droopy eyelid.
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In common cold , excessive secretions (like rhinorrhoea) are due to cholinergic overactivity. First generation antihistaminics possess anticholinergic propey and therefore are effective for common cold. On the other hand, all other conditions are allergic and reare benefited by antagonism of H1 receptors.
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Ans: d (Cancer breast)Ref: Maheshwari Ortho, 3rd ed, p. 224
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Ans. A i.e. Cu Cataract Snowflake cataract: DM Rossette cataract: Trauma Christmas tree pattern: Myotonic dystrophy Sunflower cataract: Wilsons disease Oil drop cataract: Galactosemia
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Ans. is 'a' i.e., Fever(ref Dhingra 6h/e p. 258]Fever is a symptom in case of acute tonsillitis, not chronic tonsillitis.Chronic tonsillitis is characterized by:- Recurrent attacks of sore throat or acute tonsillitis.
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rOBBINS BASIC PATHOLOGY 9TH EDITION Chapter diseases of immunity. page no 143. very low activity of adenosine deaminase in sample of red cells and high levels of dATP is consistent with diagnosis of SCID (severe combined immuno deficiency disease) . so answer is option 2. Defects in Lymphocyte Activation Rare patients ...
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(Pralidoxime) (92, 83-KDT) (105-KDT 6th)Lipid soluble agents (physostigmine and organophosphates) have more marked muscarinic and CNS effects; stimulates ganglia but action on skeletal muscle is less prominentLipid insoluble agents (neostigmine and other quaternary ammonium compounds) produces more marked effect on the...
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The patient suffers from sensorineural deafness, so fenestration and stapes mobilisation cannot be done. Such patients require heating aid or cochlear implant. Since hearing aid has not shown any benefit, cochlear implant will be indicated to provide hearing and develop speech and language. There is no conservative tre...
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Ans. is 'b' i.e. Mitochondria The fate of pyruvate formed at the end of glycolysis (glucose metabolism) is as follows :Under anaerobic conditions : Pyruvate is reduced by the NADH to lactate in the presence of Lactate dehydrogenaseUnder aerobic conditions : Pyruvate is taken up into mitochondria & is converted to Acety...
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Blood pressure decreases as the body is unable to maintain normal oncotic pressure with liver failure, so patients with liver failure require close blood pressuremonitoring. Increased capillary permeability, abnormal peripheral vasodilation, and excess rennin released from the kidney’s aren’t direct ramifications of li...
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Ans. is 'a' i.e., IL1 Pyrogeneso Pyrogenes are substances that cause fever.o Pyrogens may be exogenous or endogenous* Exogenous- Bacterial toxins* Endogenous- IL0-l,TNF-a, IL-6, Interferons, Cilioiy's neurotropic factoro These pyrogenes increase the level of PGE2 in the hypothalamus that elevates the thermoregulatory s...
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Ans. is 'c' i.e., Doxacurium Amongst the given options doxacurium is longest acting (Duration of action 90-120 minutes). Rocuronium (duration of action 30-60 minutes), Atracurium (duration of action 30-60 minutes) and vecuronium (duration of action 60-90 minutes) have shoer duration of action than doxacurium.
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palatoglossus. 1. All the muscles of the tongue except palatoglossus (cranial accessory nerve through pharyngeal plexus) are supplied by hypoglossal nerve 2. all the muscles of pharynx except stylopharangeus (glossopharengeal nerve) are supplied by pharyngeal plexus. 3. all muscles of soft palate except tensor velli pa...
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Ans. A i.e. Retention cystBailey & Love (Surgery) states that ranula is an extravasation cyst, but CSDT (Surgey), Dhingra (ENT) & even internet references describe it as retention cyst.
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Vesicles in Ramsay hunt syndrome are seen in the preauricular skin, the skin of ear canal, the soft palate and not on facial skin.
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Diverticulectomy is the most frequently chosen to treat urethral diverticulum at any site along the urethra.
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Ans. is 'a' i.e., Hypersegmented neutrophills
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Ans. D i.e. Atony of uterus An atonic uterus cannot compressed effectively due to imperfect contraction and retraction of the uterine musculature and bleeding continues So a retraced uterus rules out uterine atony as a cause of PPH Post paum hemorrhage MC cause of PPH: Atonic uterus (grand multipara, prolonged labor et...
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Ans. D: To know the position of the placenta Benefits of first trimester USG: Viability of the fetus Pregnancy dating Multiple pregnancy detection Detection of ectopic pregnancy Detection of H.Mole Detection of fetal anomalies Placental localization can be done with USG in second half of pregnancy.
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Recurrent severe infection is an indication for clinical evaluation of immune status. Live vaccines, including BCG attenuated from M. tuberculosis, should not be used in the evaluation of a patient's immune competence because patients with severe immunodeficiencies may develop an overwhelming infection (disseminated di...
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Ans. is 'a' i.e., Peussis Congenital passive immunity (maternal passive immunity) o Maternal passive immunity is a type of naturally acquired passive immunity. o It refers to antibody-mediated immunity conveyed to a fetus by its mother during pregnancy. o Impoant infection, against which immunity is transferred from mo...
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(B) Tall T wave [Harrison17 - 284; Harrison18 - 357; Harrison16 - 2621 # Most serious effect of HYPERKALEMIA is cardiac toxicity, which does not correlate well with the plasma K+ concentration.> The earliest electrocardiographic changes include increased T-wave amplitude, or peaked T waves.> More severe degrees of hype...
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Ans. A. Bartonella henselae and B.Bartonella quintanaExplanationBoth can cause:B. henselae causes hepatosplenic lesions.B. quintana cause subcutaneous and lytic bony lesions.In case question do not specify answer B. henselae.Features of Bartonella species are given in the table below:BartonellaDiseasesReservoirTransmis...
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Ans is 'a' i.e. Certain min. amount of reduced Hb should be present o Cyanosis is a blue coloration of the skin and mucous membranes due to the presence of >5g/dl reduced hemoglobin in blood vessels near the skin surface. Now since in anemia the total amount of hemoglobin is decreased, the amount of reduced Hb to produ...
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Ans. B: Vitreous defects The 3 most common causes of vitreous hemorrhage are: Proliferative diabetic retinopathy Posterior vitreous detachment (PVD) with or without retinal tears Ocular trauma (e.g., shaken baby syndrome); together these account for 60-89% of all cases. Less common causes include branch or central reti...
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Digoxin is a AV Nodal blocker and hence it leads to PR prolongation not shortening.
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Calcium content in breast milk is 28mg/100g.REF.PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE.Editon-21.Page no.-582 table 21
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EEGs recorded on the scalp can be processed to quantify the amount of activity in each of four frequency bands: Delta (o to 3hz), Theta (4 to 7 Hz) alpha (8 to 13 Hz), Beta (> 13 Hz) Between 1-2 MAC shift is towards decreased frequency. b-a-th-S
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B. i.e. Psoriasis
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Ans is 'c' i.e., Mitochondria! disorder Clinical Syndromes of Mitochondrial Diseases Primary Features Chronic progressive external o External ophthalmoplegia ophthalmoplegia (CPEO) o Bilateral ptosis o PEO onset before age 20 years o Pigmentary retinopathy o One of the following CSF protein greater than I g/L, cerebell...
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Glucose enters glycolysis by phosphorylation to glucose 6-phosphate, catalyzed by hexokinase, using ATP as the phosphate donor. Under physiological conditions, the phosphorylation of glucose to glucose-6-phosphate can be regarded as irreversible. Hexokinase is inhibited allosterically by its product, glucose-6-phosphat...
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MItral valve prolapse "Midsystolic click" are viually synonymous with prolapse of the mitral valve toward the left atrium during systole. Result of myxomatous degeneration of the valve with prolongation of the valve or chordate tendinae. Abnormal ratio between the length of the mitral apparatus and the volume of the le...
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CONCOMITANT SQUINT - type of manifest squint in which the amount of detion in the squinting eye remains constant in all directions of gaze, no limitation of ocular movements.. Any obstacles to the development of these processes result in concomitant squint . (1) Sensory obstacles -hinder the formation of a clear image ...
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Ans. is 'a > c' i.e., Most common type of genital TB > Is asymptomatic Genital tuberculosiso Almost always a secondary infection. Most common primary site is lungs (50%) fib lymph nodes (40%).o Most common route of spread is through blood.o Commonly affects sexually active age group (20-30yrs), most commonly at 28 yrs ...
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Figure: Inversion in the SMA/SMV relationship with the SMA on the right and the SMV on the left. Figure: Whirlpool sign with twisting of mesentery and mesenteric vessels, is seen in Malrotation/ MidGut Volvulus.
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Ans. C: Ochsner-Sherren regiman Appendicular mass: On the 3rd day (rarely sooner) after the commencement of an attack, a tender mass can frequently be felt in the Right Iliac Fossa (RIF) beneath some rigidity of the overlying musculature, the other quadrants of the abdomen being free from rigidity or tenderness. The ma...
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Endometriosis is not found in spleen.
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Ans. is 'd' i.e., Weight between 60% & 71% of the ha rvard standard
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The duct runs forwards for a sho distance between the buccinator and the oral mucosa. Finally, the duct turns medially and opens into the vestibule of the mouth opposite to the crown of upper second molar tooth. REF.BDC SIXTH EDITION VOL NO:3 PAGE NO:110
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Ans. is 'a' i.e., Keratin Dermatophytes are keratinophillic fungi, living only on the superficial dead keratin. That is why they infect skin, hair and nail. In skin they infect most superficial layer of the epidermis i.e. stratum corneum. They do not penetrate living tissues. Dermatophytes cause a variety of clinical c...
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Ans. is 'a' i.e., Antinuclear antibody Autoantibodies in systemic lupus erythematosus (SLE)AntibodyPrevalence %Antigen RecognizedClinical UtilityAntinuclear98Multiple nuclearBest screening test; repeated negative tests make SLE unlikelyantibodiesAnti-dsDNA70DNA (double-stranded)High titers are SLE-specific and in some ...
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MECHANISM OF ACTION IUDs Intrauterine device: Foreign body reaction in uterus Cellular and biochemical changes in Endometrium and uterine fluids. Impaired bility of gamete. Reduced chances of feilization. Copper ions (2nd generation) Alter biochemical composition of cervical mucus. Affect sperm motility/Capacitation / ...
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Delirium tremens Delirium tremens (DT) is the most severe alcohol withdrawal syndrome. It occurs usually within 2-4 days of complete or significant abstinence from heavy alcohol drinking in about 5% of patients, as compared to acute tremulousness which occurs in about 34% of patients. The course is sho, with recovery o...
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Approximately 98% of the time, ectopic pregnancies are located in the fallopian tube. It is believed that improper transpo of the feilized ovum through the fallopian tube is the most common pathophysiology leading to ectopic pregnancy. Several risk factors are associated with such improper transpo, including pelvic inf...
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Ans. is 'a' No. of crescents (Ref: Robbins (Basic) 6/e, p453]Following lines from Robbins (Basics) gives us fair idea of the answer.Robbins says about rapidly progressive glomerulo nephritis that.- " prognosis can be roughly related to the number of crescents; patients with crescents in less than 80% ~ of the glomeruli...
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Xenon [Ref: Morgan's Anaesthesia 4/e p 781, 166, 167; Miller's Anaesthesia p 626, 6491 Xenon seems to be the best answer because all other inhalational anaesthetics mentioned in the question produce some cardiovascular effects that may harm the patient with mitral stenosis. Mitral stenosis is a disorder where cardiac o...
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The two Unpaired muscles of perineal body are Longitudinal muscle of anal canal External and sphincter
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Neurofibromas and von Recklinghausen's Disease Neurofibromas may occur as a solitary, fusiform cutaneous tumor of a single nerve, but more often are multiple associated with von Recklinghausen's disease. Solitary neurofibroma is a tumor of adults but multiple neurofibromas or neurofibromatosis is a hereditary disorder ...
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Ans. (c) NADPH oxidase(Ref: R 9th/pg 48; 8th/pg 13,14)AntioxidantsEnzymesNon enzymes* Catalase- Present in peroxisomes Q decomposes H2 O2 Antioxidants- vitamins E, A and C glutathione in the cytosol.*. Superoxidase dismutases: O2- to H2 O2 *. Manganese-SOD, which is localized in mitochondria,*. Copper-zinc-SOD, which i...
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L.O.L.A: L-ornithine stimulates the urea cycle, with resulting loss of ammonia. Both L-ornithine and L-aspaate are substrates for glutamate transaminase. Their administration results increased glutamate levels. Ammonia is subsequently used in the conversion of glutamate to glutamine by glutamine synthetase. Ammonia abs...
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• Right colon is the fermentation chamber of the human GI tract • Bacteria are most metabolically active in cecum • Left colon is a site of storage and dehydration of stool.
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In cow's milk the predominant type of immunoglobulin is Ig G, while in human milk it is Ig A. Ref: Nutrition and Child Development, K.E. Elizabeth, 4th edition pg: 22
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At 4 months Lifts head and chest, with head in an approximately veical axis. legs extended Reaches and grasps objects and brings them to mouth Enjoys sitting with full trunkal suppo When held erect pushes with feet Laughs out loud Excites at sight of food Ref : Nelson 20th edit pg:67
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The kidney is innervated primarily by the sympathetic nervous system, and as such, regulates the contraction of the smooth muscle surrounding the afferent and efferent aerioles of the glomerulus. Sympathetic stimulation to the efferent glomerular aerioles causes their constriction and increases the filtration rate, lea...
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Ans. is 'd' i.e., Macrophages
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Danbury tremors are seen with chronic mercury poisoning (hydrargyrism). It occur first in the hands, then progress to lips and tongue and finally involves arms and legs. The advanced condition is called Hatter's shakes or glass-blower's shakes, because they are common in persons working in glass-blowing and hat industr...
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Answer is B (Appendicitis) Appendicitis alone does not cause increased amylase. Perforated appendix, may be associated with increased amylase. Causes of Hyperamvlasemia and Hyperamylasuria: Pancreatiti Disease Non Pancreatic Disorders Other Abdominal Disorders I. Pancreatitis A. Acute I. Renal insufficiency II. Salivar...
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Caudate process of caudate lobe of the liver forms the superior border of epiploic foramen.The right margin of the lesser sac opens into the greater sac through the opening of the lesser sac called Epiploic foramen. Boundaries of epiploic foramen are formed by: Anteriorly: Free border of the lesser omentum, bile duct, ...
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Biers&;s block is intravenous regional anaesthesia
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C i.e. Increase in alveolar surface area by the surfactant
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Ans. Barium meal
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Dying deposition is recorded by magistrate.
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Since Hb has more affinity to CO than oxygen, it results in anaemic hypoxia. PO2 remain normal as it is the dissolved form. Hb-O2 dissociation curve shifts to left. Treatment for CO poisoning is by hyperbaric oxygen. But 95% O2 + 5% CO2 can also be used. CO is a gaseous vasodilator.
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A continuous murmur is predicated on a pressure gradient that persists between two cardiac chambers or blood vessels across systole and diastole. The murmurs typically begin in systole, envelop the second heart sound (S 2 ), and continue through some portion of diastole. They can often be difficult to distinguish from ...
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Recurrent dislocation: In some, joints proper healing does not occur after the first dislocation. This results in weakness of the suppoing structures of the joint so that the joint dislocates repeatedly, often with tril trauma. Recurrent dislocation of the shoulder and patella are common. among shoulder anterior type o...
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ANSWER: (D) 420REF: This is a question of simple mathematical calculationAverage reproductive life is 35 years from puberty to menopause << There are 12 menstrual cycles every yearOne secondary oocyte is produced in each cycleSo the total number of secondary oocytes produced in female will beSec Oocyte = 35 x 12 x 1= 4...
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Ans. b. OsteosarcomaOsteosarcoma is the second most common tumour.These tumours occur b/w the ages of 15-25 years, constituting the commonest musculo-skeletal tumour at that age
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(Ref: KDT 6/e p841) By inhibiting the enzyme IMP dehydrogenase, mycophenolate inhibits the de novo synthesis of purines.
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The patient in the question: Was being treated for infertility. Now H/O 6 weeks of amenorrhea. Presents with urinary retention. The first diagnosis which comes in our mind is the retroverted gravid uterus. Points which favour the diagnosis are: The woman is pregnant and has complained of urinary retention. But friends...
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Ans. is 'd' i.e., Anti coagulation
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Following image shows a defect in the orbital floor and the 'tear drop' sign in the antrum characteristic of blow out fractures of orbit. WATER'S view on X-RAY is helpful in eliciting orbital blow out fracture
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Solution: When RBCs are Passing through splenic Circulation and fibrotic area biconcave RBCs becomes Tear Drop RBCs.
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Gall stone ileus Passage of stone through a spontaneous biliary-enteric fistula leading to a mechanical bowel obstruction Clinical features Rigler's triad : Classic plain abdominal film triad of small bowel obstruction, pneumobilia & ectopic gallstone Ref: Sabiston 20th edition Pgno :1506-1507
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Bronchial aeries supply the thoracic pa of esophagus. Inferior thyroid aery provides primary aerial flow to the cervical esophagus, and subclan aery, main carotid aery, veebral aeries, ascendant pharyngeal aery, superficial cervical aery, and costocervical trunk are other aerial blood flow providers to cervical esophag...
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Black dot lesions are seen in Tinea capitis. The hairs are broken at the level of the skin surface producing a picture of black dots in an area of alopecia. T. tonsurans is the chief cause of "black dot" tinea capitis.
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When the cAMP levels are low- there is no binding of CAP to CAP site. | No ourable interaction for RNA polymerase. | Lac operon is not expressed. - option a is excluded. When glucose is available, Lac operon is not expressed Attenuation is seen in tryptophan operon, not Lac operon For optimal expression of lac operon, ...
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Karyotypic abnormalities of Turner syndrome :u45 XO karyotype uIsochromosome of long arm resulting in loss of sho arm - 46X i(X)(q10)uDeletion of a poion of both long and sho arm of X resulting in a ring chromosome - 46X r(X)uDeletion of a poion of a sho arm of X - 46X del(Xp)uDeletion of a poion of a long arm of X - 4...
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Adenomyosis has no malignant potential Risk factors for Carcinoma Gallbladder Gallstones >3cm Procelain gallbladder Anomalous pancreaticobiliary junction (APBDJ) Choledochal cysts Adenomatous polyps Primary sclerosing cholangitis Obesity Salmonella typhi infection Ref: Sabiston 20th edition Pgno :1510
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Ans. A: McMurray's Test McMurray's test is performed for meniscus injury For medial meniscus: Patient lying flat (non-weight bearing), the knee is completely flexed. The foot is rotated externally and the leg abducted. The joint is now slowly extended keeping the leg externally rotated and abducted. As the torn cailage...
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When there is an ECF volume expansion, there is increased renal blood flow and increased GFR. When renal blood flow is more, the solutes in renal medulla are washed off. And this reduces the medullary concentration. Similarly, when increased GFR, Na+ reabsorption power is decreased, this leads to a decrease of the medu...
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C i.e. The site for storage of long term memory is in temporal lobe - Mechanism of learning and long term memory include gene activation leading to tprotein synthesis & spatial reorganization (restructuring) of synapse changing their sensitivity by increasing the number of transmitter vesicles / vesicle release sites /...
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All are aryl phosphate except malathion which is a alkyl phosphate. Alkyl phosphates are: HETP TEPP (Tetron) OMPA Dimefox Isopestox Malathion (Kill bug; Bugsolin) Sulfotepp Demeton Trichlorfon Aryl phosphates are: Parathion (nitrostigmine) (Follodol; Kill phos; Ekato) Paraoxon Methyl-parathion (Metacide) Chlohion Diazi...
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RK virus Herpesviridae 1-Herpes simplex virus type -1 HSV-1 2-Herpes simplex virus type -2 HSV-2 3-Varicella --Zoster virus VZV 4-Epstein- Barr virus EBV 5- Cytomegalovirus CMV 6-Human herpes virus type-6 HHV-6 - * Human erpes virus ype-8- Human herpes virus type-8 * _ HHV-8 REF : ananthanarayana 10th ed
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Resting hea rates <60 beats/ min are very common in young healthy individuals and physically conditioned subjects. By definition, sinus bradycardia is a rhythm driven by the SA node with a rate of <60 beats/min; sinus bradycardia is very common and typically benign. A sinus rate of <40 beats/min in the awake state in t...
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Calcitonin is produced by thyroid C cells and functions As an antihypercalcemic hormone by inhibiting osteoclast-mediated Bone Resorption. Calcitonin production is stimulated By calcium and pentagastrin and also by catecholamines, cholecystokinin, And glucagon. When administered intravenously to Experimental animals, i...
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Turner syndrome is characterized by a constellation of findings that result from paial or complete monosomy of the X chromosome. It is the most common chromosomal abnormality in females, with an incidence of 1 per 2500 to 3000 liveborn girls, which corresponds to approximately 2 million cases worldwide. Turner syndrome...
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Ans: b
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Ans: bRef: Harrison, 16thed, p. 264
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Ans. (b) B/L milky discharge with squeezing from multiple ductsRef: Bailey and Love 27th edition page 864* Bilateral milky discharge is from physiological lactation All other secretions may be pathological.
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The predisposing factor of germ cell tumors of testes are : Cryptorchidism Testicular feminisation syndrome Klinefelter syndrome Excess 12P copy number either in the term of i( 12P) or increased 12P an aberranthy banded marker chromosome. In most large testicular tumour approximately 10% associated with Cryptorchid...
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In a larger bruise, the colour change stas from periphery (healing of contusion) The contusion regains its normal colour in 1-2 weeks.
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Both REF: Manson's tropical diseases By Gordon C. Cook, Patrick Manson, Alimuddin Zumla Page 566, Elapid and Colubrid venoms activate complement alternative pathway (cobra venom factor), Russell's viper classical pathway Southern pacific rattle snake inactivates both alternate and classical pathway
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A few of the common facial expressions and the muscles producing them are given below. 1. Smiling and laughing: Zygomaticus major 2. Sadness: Levator labii superioris and levator anguli oris 3. Grief: Depressor anguli oris 4. Anger: Dilator naris and depressor septi 5. Frowning: Corrugator supercilli and procerus 6. Ho...
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A i.e. Neck In cases of death due to asphyxia, especially in hanging & strangulation, neck should be opened lastQ, so as to provide a clear field devoid of blood during dissection thus avoiding aificial haemorrhages. - In these cases, skull is opened first and brain is taken out to drain out the blood from neck. And ch...
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Testosterone is a Cl 9 steroid that is synthesized from cholesterol within the interstitial Leydig cells. Ref: Ganong's Review of Medical Physiology, 22nd Edition, Pages 424-25; Good Clinical Practice in Assisted Reproduction By Paul Serhal, Caroline Oveon, 2004, Page 25.
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