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Ans. is 'a' i.e., Modified macrophages Pathologic Features of Acute Rheumatic Fever Aschoff bodies focal inflammatory lesions seen in acute rheumatic fever consisting of foci of T lymphocytes, occasional plasma cells, and plump activated macrophages. These activated macrophages called Anitschkow cells (pathognomonic fo...
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Ans. is (a) i.e. 20-24degC for 5 days
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Ans. is 'c' i.e., -55 mv * The action potential, which is recorded using an intracellular electrode, has following phases : -1) Resting stage:# This is the resting membrane potential before the action potential. At rest, membrane is said to be "polarized" because - 70 mV negative membrane potential (RMP) that is presen...
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A i.e. Axonal degeneration
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Tinel's sign : It records regeneration of nerve by Tapping on the nerve course from distal to proximal direction, tingling sensation is felt at the sprouting nerve ends till the distal course of the nerve (law of Projection)
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Ectoderm REF: Yanoff & Ducker- ophthalmology 2' edition page 22-23, parson 20th edition page 5, Khurana 4th edition page 10 DEVELOPMENT OF OCULAR STRUCTURES: Neuroectoderm Surface ectoderm Mesoderm * Epithelium of iris and ciliary * Conjunctival and corneal * Sclera bodies epithelium * Corneal stroma and * Muscles of i...
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- Clinical features given suggests the diagnosis of Acute erosive gastritis. - Acute hemorrhagic gastritis-imbalance between protective and damaging factors Necrosis of mucosa is seen RISK FACTORS- Alcohol Drugs - NSAIDS and Anti-cancer drugs Uremia Stress- ICU, burns- curling ulcer clinical feature- Epigastric pain, n...
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.Vipoma -* Arising from D2 cells of pancreas * Watery diarrhoea, hypokalaemia, achlorohydria (WDHA syndrome) * Also called as pancreatic cholera or Verner- Morrison syndrome, weak - tea syndrome * Usually malignant * Secretes vasointestinal polypeptide > 150 pg/ml * Common in body and tail - solitary * Distal pancreate...
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Chemiclave: A form of autoclave, used to sterilise surgical instruments, that incorporates steam, alcohol and formaldehyde under pressure. Sterilization requires no drying time. Along with chemical vapor, this method involves high-pressure, high-temperature water and alcohol.  The medical instruments come out ready to ...
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Ans. No conduct money is given
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Ans. is 'a' ie. (Gram +ve) Actinomyces is an organism of the group ActinomycetesActinomycetes are bacteria but they form long branching filaments that resemble the hyphae of fungi.There are two medically important organismsActinomyces israelii &Nocardia"Actinomycetes are Gram positive, non motile, nonsporting noncapsul...
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Ans. B. 4 - 8 yrsPehe's disease is also known as osteochondritis deformans juvenilis or Coxa plana or Pseudocoxalgia.Pehe's disease is an osteochondritis of the epiphysis of the femoral head (capital femoral epiphysis).The disease occurs commonly in males in the age group of 5-10 years.
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Ans. is 'b' i.e., Huntington's disease Huntingtons disease is caused bv triplet repeat expansion nucleotideo Huntington disease (HD) is caused by expansion of the cytosine-adenin e-suanine (CA G) trinucleotide repeats in the HTT sene (also known as the HD or IT15 gene) located on chromosome 4pl6.3 that encodes the prot...
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Ans. A: 72 Mode is the commonly occurring value in a distribution of data. It is the most frequent item or the most fashionable value in a series of observations. The mode or the most frequently occurring value is 72. The advantages of mode are that it is easy to understand, and is not affected by the extreme items. Th...
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Alkaline phosphatase - There are four major sources of Alkaline phosphatase in the body. These are:- Liver        Bone     Intestine Placenta So the normal serum alkaline phosphatase consists of 4 isoenzymes secreted from the above-mentioned sites. Placental alkaline phosphatase is elevated in the following condition...
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Ans-C
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Ans. is 'c' i.e., Molluscum contagiosum (Ref: Ananthanarayan, 9th/e, p. 465 and 8th/e, p. 465)* Humans are the only susceptible host. This disease is caused by molluscum contagiosum belongs to poxvirus. It is an enveloped, dsDNA - containing virus with complex symmetry. This is a noncultivable virus.* The infection is ...
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Aspirin inactivates cyclo- oxygenase by irreversible acetylation of the enzyme and thereby inhibit the synthesis of thromboxane A2 even in low doses (75mg/day). From medical pharmacology padmaja 4th edition page no 344
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(Ref: KDT 6/e p286) * Steroids result in osteoporosis on long term use.
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Black spots or floaters in front of the eyes may appear singly or in clusters. They move with the movement of the eyes and become more apparent when viewed against a clear surface e.g., the sky. Common causes of black floaters are:  Vitreous hemorrhage Vitreous degeneration e.g., - senile vitreous degeneration, vitreo...
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Common causes of papillary necrosis are diabetes mellitus, analgesic nephropathy, sickle cell disease and urinary tract obstruction. Diabetes mellitus is the most common cause of renal papillary necrosis. Analgesic nephropathy is associated with the use of more than 1 kg analgesics. Ref: Radiology Illustrated: Uroradio...
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Cardiovascular impairment and direct effect of pressure on lung tissue are some of the complications of positive intrathoracic pressure. Barotrauma manifests as subcutaneous emphysema, pneumothorax, or pneumomediastinum. Ref: Clinical Intensive Care and Acute Medicine, Ken Hillman, Gillian Bishop, Pages 377-378 ; Harri...
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Facilitated diffusion is a form of transpoer-mediated membrane transpo that does not require energy input. Just as in passive diffusion, the transpo of ionized and non-ionized compounds across the plasma membrane occurs down their electrochemical potential gradient. Therefore, steady state will be achieved when the ele...
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Ans. b (TB (Tuberculoid type)) (Ref. Park PSM 20th/158, 258; Ananthanarayan Microbiology 4th ed., 365))Rook's textbook of dermatology 29.1-29.19:Lepromin test is strongly positive in patient with good CMI, i.e., tuberculoid type, and gets weaker as one passes through the spectrum of lepromatous end, the typical leproma...
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Ans. is 'c' i.e., Clostridium nouyi
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AL amyloid usually consists of the variable region of immunoglobulin light chains and can be derived from either the kappa (k) or lambda (l) moieties. Since the light chains produced by the neoplastic cells in plasma cell dyscrasias are unique to each patient, AL amyloid isolated from different persons differs in its a...
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Misoprostol is a synthetic PGE1 analogue. It inhibits gastric acid secretion and exes mucosal-protective propeies. Misoprostol in combination with mifepristone or methotrexate is highly effective in the termination of the early pregnancy. Must know: PGE2 analogue is dinoprostone, PGF2a analogue is carboprost, and PGI2 ...
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Superior thoracic apeure is not bounded by Xiphoid process B D CHOURASIAS HUMAN ANATOMY UPPER LIMB THORAX VOLU, 1 SIXTH EDITION, PAGE NO, 190
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Ans. is 'd' i.e., 5HT1A receptors Buspironeo Buspirone is the first azapirone, a new class of anxiolytic drugo Buspirone is a non-sedative, non-habit forming anxiolytic.o It differs from BZDs.1. Does not produce sedation or cognitive/functional impairment2. Does not produce tolerance or physical dependence.3. Has no mu...
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Denturist  Is a term applied to those dental laboratory technicians who are permitted to fabricate dentures directly for patients without a dentist's prescription. They may be licensed or registered. Essentials of preventive and community dentistry  Soben Peter  5th edition
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Ans. b. Sex (Ref: Modern Medical Toxicology/p4)Ashley's rule is used to know the sex of sternum; It is also known as '149 rule'Differences between Male & Female sternumFeaturesMale sternumFemale sternumBodyBigger, longer & more than twice the length of manubriumShorter & less than twice the length of manubriumAshley's ...
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Structures deep to flexor retinaculumLateral compament : Flexor carpi radialis tendon with its synol sheath lodged in the groove on the palmar surface of trapezium.Medial compament : (carpal tunnel proper).Median nerveFlexor pollicis longus with its synol sheath (radial bursa)4 tendons each of flexor digitorum superfic...
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Menkes kinky hair syndrome is an X-linked metabolic disturbance of copper metabolism characterized by mental retardation, hypocupremia, and decreased circulating ceruloplasmin. This syndrome is caused by mutations in the copper-transpoing ATP7A gene. Children with this disease often die within 5 years because of dissec...
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About option (a) Barrett's esophagus is more common in men than in women (3 : 1 ratio) About option (c) Schwartz surgery and CSDT writes that Barrett's esophagus can be reversed but only with antireflux surgery (response to medications is not good). Read below lines from CSDT (13/e p438) Schwartz (9/e p841): CSDT ...
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Carboxylation The only known biological role of vitamin K is as a cofactor for an enzyme carboxylase that catalyzes carboxylation of glutamic acid residues on vitamin K-dependent proteins. The key vitamin K-dependent proteins include: Coagulation proteins: factors II (prothrombin), VII, IX and X Anticoagulation protein...
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Ans. (a) Dark fieldDarkfield microscopy reduces the amount of light entering the lens system of a microscope in two ways. First, it blocks the center of the beam of light that would otherwise fill the objective lens. Second, only the light which is scattered by the specimen and enters the objective lens is seen
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Ans. Endrin
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A i.e. Tympanic membraneTympanic membrane derived from first pharyngeal membrane (which seperates 1st pharyngeal groove from 1st pharyngeal pouch) represents all three layers of embryonic disco. It develops from three sources. 1) External very thin skin is derived from ectoderm of 1st pharyngeal groove; 2) Medoderm of ...
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Increased Indirect bilirubin, LDH, AST, urobilinogen in urine and stool are seen in hemolysis. Serum haptoglobin will be reduced. ALT will be normal in hemolytic anemia. Ref: Harrisons Principles of Inernal Medicine, 18th edition, Page : 873
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Precocious puberty is the appearance of appropriate secondary sexual characters before the age of 8 years and occurrence of menstruation before 10 years of chronological age. Also know : Delayed puberty : is considered delayed when the secondary sexual characters do not appear by the age of 14, and menarche is not esta...
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The second hea sound is widelysplit and is relatively fixed in relation to respiration. A mid-diastolicrumbling murmur, loudest at the fouh intercostal space and alongthe left sternal border, reflects increased flow across the tricuspidvalve. In ostium primum ASD, an apical holosystolic murmur indicatesassociated mitra...
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L-H type of Reid Steinberg (RS cell) - Non classical variant of HL (CD15-ve, CD30-ve) Lymphocyte predominant HL - best prognosis Nodular sclerosis HL - lacunar R-S cell (common subtype all around the world) Lymphocyte predominance type expresses B cell markers and is not associated with EBV
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Erythrocyte antibody complement rosetting (EAC-rosetting), occurs when antibody in the presence of complement is bound to the surface of a red blood cell. The complement binds to the tail region (Fc region) of the antibody. Finally T-cells with a complement receptor are added and the T-cells bind to the complement on t...
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The features described are suggestive of lateral medullary syndrome(Wallenberg syndrome). Ipsilateral sensory loss over face and contralateral loss of pain and temperature over body. There is no muscle weakness.
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Nodular lesions of diabetic glomerulosclerosis are also called as Kimmelstiel-Wilson (KW) lesions or intercapillary glomerulosclerosis.These lesions are specific for type 1 diabetes (juvenile onset diabetes) or islet cell antibody-positive diabetes mellitus. The pathologic changes consist of one or more nodules in a fe...
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TumourIncidence%Insulinoma70-80Gastrinoma20-25Non-functional tumours30-50VIPoma4Glucagonoma4Somatostatinoma<5Carcinoid<1ACTHoma<1GRFoma<1Ref: Bailey and Love 27e pg: 846
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Mumps occur between the ages of 5 & 15. Infants are rarely involved due to presence of transplacentally acquired maternal mumps antibodies. Ref: O P Ghai Essential Pediatrics, 6th Edition, Page 209
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Ans. c. M3Ref: Goodman Gilman 13th E/P157M3 are Gq subtype of GPCR, which increase calcium and that causes contraction of detrusor. In case of overactive bladder inhibition of M3 is crucial for treatment by anticholinergics.Anticholinergics used in overactive bladder are:OxybutininTolterodineFesoterodineFlavoxateTrospi...
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Ans is C (Ca breast) "Fat necrosis of the breast is a unilateral localized process associated with trauma, breast biopsy, reduction mammoplasty, and radiation. It is easily confused with cancer due to induration, fibrosis, dystrophic calcification, and retraction of overlying skin; the key distinction is the presence o...
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CEFOPERAZONE: Like ceftazidime, it differs from other third generation compounds in having stronger activity on Pseudomonas and weaker activity on other organisms. It is good for S. typhi and B. fragilis also, but more susceptible to
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Nevus sebaceous appears usually on the scalp. Made of extra sebaceous glands in the skin. It stas as a flat pink or orange plaque (slightly raised area). Hair does not grow in a nevus sebaceous. During adolescence, they can become very bumpy and wa- like. A nevus sebaceous does not go away on its own. T/t: Surgery Seba...
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ANSWER: (A) T cell lymphomaREF: Harrison's 18th ed chapter 110B CellT CellHodgkin's DiseasePrecursor B cell neoplasmPrecursor T cell neoplasmNodular lymphocyte- predominant Hodgkin's diseasePrecursor B lymphoblastic leukemia/ lymphoma (precursor B cell acute lymphoblastic leukemia)Precursor T lymphoblastic lymphoma/leu...
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(Ref: KDT 6/e p840) Cyclosporine and tacrolimus cause nephrotoxicity as an adverse effect. Sirolimus (rapamycin) results in bone marrow suppression and thus may cause anemia, thrombocytopenia and leukopenia.
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In the presence of enough vasopressin to produce maximal antidiuresis, water moves out of the hypotonic fluid entering the cortical collecting ducts into the interstitium of the cortex, and the tubular fluid becomes isotonic.
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The spinous (prickle) cells resemble a cocklebur or sticker that has each spine ending at a desmosome. Of the four layers, the spinous cells are the most active in protein synthesis. These cells synthesize additional proteins that differ from those made in the basal cells.
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Mass spectrometry (MS) is a very sensitive quantitative analytixal technique used to measure a wide range of clinically relevant analysis.MS identifies molecules based on their mass or molecular size. A sample is vapourized sucj that positive charge is produced on the molecule.Electrical field is applied, so that paicl...
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Ans. A. Abnormality in gene for procollagenEhlers-Danlos syndrome comprises a group of inherited disorders whose principal clinical features are hyperextensibility of the skin, abnormal tissue fragility, and increased joint mobility. The clinical picture is variable, reflecting underlying extensive genetic heterogeneit...
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Caldwell luc approach opens maxillary sinus. Ref- Dhingra, 6th edition, Page 412.
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Heat cramps occur when a person is doing heavy muscular work in high temperature and humidity. There is painful and spasmodic contraction of muscles. It is believed to be due to losses of sodium and chloride in sweat. Ref: Park 21st edition page: 690.
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Primiparous is at a higher risk than multiparous lady H.mole due to abnormal trophoblastic proliferation and uterine distension is at higher risk. Infact h.mole is associated with early onset preeclampsia. Previous h/o preeclampsia also increases risk.
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The oculomotor nucleus is located in the central grey matter of midbrain at the level of superior colliculus. The oculomotor nucleus is in the ventromedial pa. The Edinger - Westphal nucleus (visceral oculomotor nucleus) is located dorsal to the rostral two-thirds of main oculomotor nucleus. (Ref: Vishram Singh textboo...
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Cardiac output = stroke volume x hea rateStroke volume depends on end diastolic volume. End-diastolic volume depends on several factors like venous return. Venous return is decreased in standing posture due to pooling of blood in lower extremities and is maximum in lying down position. EDV also depends on ventricular f...
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Expe witness (Sec. 45 IEA ): person who has been trained or skilled in technical or scientific subject. Only an expe witness may volunteer a statement, if he thinks that injustice will result if he fails to make the statement. Examples of expe witness: Handwriting or fingerprint expe, doctor,chemical examiner. Hostile
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Eutectic mixture of local anaesthetics (EMLA) is a mixture of 2.5% lidocaine and 2.5 prilocaine.
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Professional antigen-presenting cells, including macrophages, B cells and dendritic cells, present foreign antigens to helper T cells, while other cell types can present antigens originating inside the cell to cytotoxic T cells Reff: Ananthanarayanan & Panikers textbook of microbiology 9th edition pg: 137
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Ans. (a) Median nerve.
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Cutaneous anthrax Anthrax is primarily a disease of the domestic animals. Humans are usually accidental hosts when brought into contact with infected animals There are three major forms of disease: Cutaneous anthrax Acquired, skin Inhalational anthrax --> Inhalated, spores Gastrointestinal anthrax Analogus to cutaneous...
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In resting muscle, troponin I is bound to actin and tropomyosin covers the site where myosin head interacts with actin. Ref: Ganong&;s Review of medical physiology;25th edition; pg: 104.
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H3 receptors act as pre-synaptic receptors and decrease the release of histamine and other neurotransmitters. These antagonize H1 mediated wakefulness and bronchoconstriction. These also decrease gastrin release and produce negative chronotropic effect. Inverse agonist of H3 receptor (tiprolisant) is approved for Narco...
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- Sloughing of decidual tissue results in a vaginal discharge of variable quantity. For the first few days after delivery, there is blood sufficient to color it red--lochia rubra. - After 3 or 4 days, lochia becomes progressively pale in color--lochia serosa. After approximately the 10th day, because of an admixture of...
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In primary sclerosing cholangitis, Liver enzymes are elevated, Bilirubin levels increase during acute cholangitis. Reference: Davidson, 23rd edition, page 889
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Femite solution is primarily used to prevent topical infection over the skin. The active constituent of the medication is known to be the most bitter substance available. Just a few parts of it per million will make the product so bitter that children and pets would not be able to swallow it. The femite is applied in t...
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Ref Harrison 19 th ed pg 1540 general, the duration of this murmur correlates with the severity of the stenosis in patients with preserved CO. In patients with sinus rhythm, the murmur often reappears or becomes louder during atrial systole (presystolic accentuation). Soft, grade I or II/VI systolic murmurs are commonl...
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A i.e. 2 D Echocardiography M- Mode Echo is also k/a One dimensional echo, it uses stationary beam so informations are updated very rapidly. It is often more conventient for assessing distance & motion of selected cardiac structure. 2-Dimensional echo has replaced it for most diagnostic purposes. It is expected that 3D...
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The difference between the amount of diphtheria toxin that will exactly neutralize one unit of antitoxin and that which, added to one unit of antitoxin, will leave one lethal dose free is greater than one lethal dose of toxin; i.e., it is necessary to add more than one lethal dose of toxin to a neutral mixture of toxin...
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X-ray show normal right side of hip joint.In left side of hip joint, the epiphysis is smaller,shallow acetabulum and the hip joint is dislocated- indicates Developmental Dysplasia of Hip (DDH). Pehes is avascular necrosis, seen in the proximal pa of the femur. SCFE is Slipped capital femoral epiphysis. Fracture of neck...
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Ans. is c i.e. Fetal Scalp pH > 7.3 Het. Normal fetal scalp pH ranges from 7.25 to 7.35. Fetal hypoxia is indicated by 'acidosis' or fall in fetal scalp pH to values below normal (Not by increase). It is used to corroborate the significance of fetal CTG (Cardiotocography) Interpretation of Fetal Scalp blood sampling PH...
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Ans. B: Trigeminal Neurotrophic keratopathy occurs in cases in which trigeminal nerve is paralyzed, typically as a result of radical treatment for trigeminal neuralgia. It does not occur in all cases of peripheral lesions of the trigeminal nerve; thus, if the gasserian ganaglion is removed or the trigeminal nerve with ...
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Atosiban [Ref: Ian Donald practical problems in obstetrics 6h/e Most tocolytics are contraindicated in women with cardiac disease because of their potential to precipitate cardiac failure. - As there are no studies performed to look at the safety of tocolytic drugs in setting of existing hea failure the recommendations...
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Ans- D Erythematous urticarial patches and plaques (classically periumbilical) that progress to tense vesicles and blisters in a pregnant woman is herpes gestationis (also known as pemphigoid gestationis). There is no association to the husband's URI. Herpes gestationis is a pruritic blistering dermatologic disorder un...
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IUCD: Can prevent implantation up till 5th day of unprotected inter-course Therefore, this is the most effective method for contraception
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Ans. a (Bone marrow). (Ref: Ananthnarayan, Microbiology/6th ed., 116)# B lymphocytes precursors, pro-B cells develop in the fetal liver during embryonic life and in bone marrow afterwards continuously throughout life.# Rearrangement of Ig genes takes place on their becoming preB cell, which synthesize cytoplasmic IgM.#...
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60 -- 70 days
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Hypehyroidism
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The Lachman test is the most sensitive test for ACL tears. It is done with the knee flexed at 20 degrees, stabilizing the distal femur with one hand and pulling forward on the proximal tibia with the other hand. Ref: Maheshwari 6e pg 358.
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MACULE: well demarcated ,non palpable discolouration of skin less than /equal to 1 cm. PATCH: well demarcated,non palpable discolouration of skin >1cm. PLAQUE: well circumscribed,solid,plateau like lesion >1 cm with a major poion of lesion above skin surface. PAPULE: well circumscribed,solid,plateau like lesion less th...
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(All of the above) (19-Sutton 7th)MAGNETIC RESONANCE IMAGINGADVANTAGESDISADVANTAGES* It is non-invasive technique* It is safe as it does not involve the use of ionising radiation* There is no adverse biological effect.* Images can be readily produced in any plane eg. Axial sagittal or coronal without changing position ...
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Ans. a. Self-exemption (Ref: style="font-size: 1.04761904761905em; font-family: Times New Roman, Times, serif">; Kaplan and Sadock 11/e p590)There are many psychological barriers that need to be overcome in order to successfully quit smoking. Self-exempting belief is one of them."Self-exempting beliefs: A large majorit...
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Ans. is'a'i.e., MaxillaryMaxillary sinus is also called Antrum of Highmore.
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Ans. is 'a' i.e., Cross reactivity with endogenous antigen Acute Rheumatic fever results from immune response to group A streptococci.The main factor responsible for virulence in infection with streptococcal A group is "M" protein.The body mounts an immune response against streptococci A organism by producing antibodie...
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Color codingType of containerWaste categoryTreatment optionsYellowPlastic bagCat 1, 2, 3 & 6Incineration/deep burialRedDisinfected container/plastic bagCat 3, 6 & 7Autoclaving/Microwaving/Chemical treatmentBlue/White translucentPlastic bag/Puncture proof containerCat 4 & 7Autoclaving/Microwaving/Chemical treatment and ...
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Ans. d (Law of Projection) (Ref. Ganong Physiology 22nd/pg. 126)Phantom limb is post-op complication of amputation of limb where patient feels amputated limb and sometimes it becomes painful. It is best explained by law of projection.Weber-Fechner LawMagnitude of sensation felt is proportionate to the log of intensity ...
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Most meniscal tears are produced by flexion and rapid rotation. A classic example ("football knee") involves a player who is hit while running. The knee, supporting all the player's weight, usually is slightly flexed, and the foot is anchored to the ground by cleats. Impact from an opposing player usually causes rotati...
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Ans. is 'b' i.e., 19-5 mg MALA-D contains - i) 30 ug (0.03 mg) of ethinyl estradiol. ii) 0.15 mg of desogestrel (D-norgestrel). Each brown coloured film coated tablet contains 60 mg ferrous fumarate equivalent to ferrous iron 19.5 mg.
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Ans. is 'c' i.e., USG o U/S scrotum is done for any suspected testicular tumory If a testicular mass found on U/S then high inguinal orchiectomy done to remove the primary as well as know about the histology- of the tumor.After orchiectomy further inv. done for staging are : -CT abdomen & pelvisChest x-rayChest CTSerum...
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The Prausnitz-Kustner test (PK test, Prausnitz-Kustner reaction) is an immunologic test formerly used by physicians to determine if a patient has an allergic reaction to a specific antigen i.e, IgE Ref: Ananthanarayan & Parkers textbook of microbiology 9th edition pg:98
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Ans. c (Amyloid Beta-2 Microglobin) (Ref. Robbins Pathologic basis of disease 8th/ Table 5-12.)Patients on long-term hemodialysis for renal failure develop amyloidosis owing to deposition of b2 -microglobulin.This protein is present in high concentrations in the serum of patients with renal disease and is retained in c...
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Post ganglionic sympathetic (Type C) has the least conduction velocity among the given options Types of nerve fiber Fiber type Function Fiber diameter(mcm) conduction velocity (m/s) A alpha Proprioception 12-20 70-120 A beta Touch, pressure 5-12 30-70 A gamma Motor to muscle spindles 3- 15-30 B Preganglionic autonomic ...
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Ans. is 'b' i.e., 90 % Chicken poxo Causative agento Portal of entryo I. P.o Infectious periodo Secondary attack rate is higho Age group- varicella zoster virus (Herpes simplex type III)- Respiratory tract or conjunctiva- 10-21 days.- 2 days before and 5 days after the onset of rash.- 90%-5-9 Yrs.o C/Fs - has two stage...
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Harrison's principles of internal medicine 17th edition. * Majority of patients need to use continuous positive airway pressure(CPAP) delivered by a nasal mask every night to splint the upper airway open.
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