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Ans. is 'b' i.e., Respiratory route Myxoviruses Myxoviruses are enveloped RNA viruses. They are characterized by ability to adsorb on to mucoprotein (affinity for mucin) on erythrocytes causing agglutination of erythocytes.
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Ans. (b) Normal Tension GlaucomaRef: Kanski 7/e, p. 346; Yanoff 3/e, p. 1159Glaucomatous cupping (large and deep cup) along with glaucomatous visual field defects (paracentral scotomas are the most frequent) in patients with normal intraocular pressure suggests a diagnosis of Normal Tension Glaucoma (NTG).
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Hemophilia is an X-linked recessive hemorrhagic disease due to mutation in the F8 gene (Hemophilia A or Classic Hemophilia) or F9 gene (Hemophilia B). Males subjects are clinically affected; women who carry single mutated gene are generally asymptomatic. Ref: Kliegman, Behrman, Jenson, Stanton (2008), Chapter 476, "Her...
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inJune 2009 a new strain of H1N1 influenza called swine flu was declared to be a global pandemic by the WHO REF : ANANTHNARYANA
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The minimum recommended concentration of free chlorine is 0.5 mg/L for one hour. The free residual chlorine provides a margin of safety against subsequent microbial contamination such as may occur during storage and distribution. The sum of the chlorine demand of the specific water plus the free residual chlorine of 0....
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Ans. is 'a' i.e., AL In Multiple myeloma the amyloidosis is AL type (primary amyloidosis). Primary amyloidosis o It is the most common form of amyloidosis. o It occurs when there is immunocyte dyscrasias. o Best defined example is multiple - myeloma. o But, The great majority of patients with primary (AL) amyloid do no...
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Answer- D. HypoglycemiaLocal side effects include hoarseness (dysphonia) and oral candidiasisgrowth retardation in children or to osteoporosis in adults.bruising, petechiaeHyperglycemia & pituitary- adrenal suppression
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The above image is that of cellulitis of the leg.Cellulitis is a non-suppurative, invasive infection of tissues, which is usually related to the point of injury.Typically caused by B haemolytic streptococci, staphylococci and Clostridium perfringens. Streptococci being the commonest.Necrotising fasciitis is mostly poly...
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Ans. D >170 mm HgRef: Harrison's, 19th ed. pg. 1616Guidelines for threshold values between normal and high blood pressure Clinic measurement (mm Hg)Home measurement (mm Hg)Optimal control<140/85<130/80Mild hypertension140-150/90-100135-145/85-95Moderate hypertension150-170/100-110145-165/95-105Severe hypertension>170/1...
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Ans. is 'b' i.e., Air-conditioning
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Bilious vomiting is the most common symptom of intestinal obstruction in newborn Proximal obstruction- history of polyhydramnios is common Obstruction high in the intestinal tract results in frequent, bilious emesis with little or no abdominal distention. Distal obstruction- Abdominal distension and constipation are mo...
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Health risks associated with Polycystic ovary syndrome (PCOS) Type II Diabetes Hypeension Coronary aery disease Lipidaemias Premature Ovarian failure Breast Cancer Endometrial cancer Pregnancy risks associated with Poly-cystic ovary syndrome (PCOS) Gestational diabetes (diabetes that occurs during pregnancy) Pregnancy ...
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Mixed Coho Studies Combination of Retrospective Coho study + Prospective coho study The coho is identified from past records and is assessed till date for the outcome. (Retrospective coho) The same coho is followed up prospectively into future for fuher assessment of outcome. (Prospective coho)
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Gallamine
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Metacercaria larva are the infective form for all the trematodes, expect Schistosoma where cercarial larva are the infective form.
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Sho head of the biceps brachii arises from the lateral pa of the tip of coracoid process and gets attached to the posterior rough pa of radial tuberosity . B D Chaurasia 7th edition Page no : 91
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Delayed-type hypersensitivity is defined as a tissue reaction involving lymphocytes and mononuclear phagocytes,which occurs in response to a soluble protein antigen and reaches greatest intensity 24 to 48 hours after initiation. In the initial phase, foreign protein antigens or chemical ligands interact with accessory ...
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Hippocratic facies--bright, hollow eyes; pale, pinched face; cold perspiration in eye brows; dry, fissured tongue; blue lips. Patient will be in severe shock. It signifies terminal status with high moality rate. It is a typical facial sign of severe end stage peritonitis.Reference : page 572 SRB's manual of surgery 5th...
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Ans. is 'b' i.e., Streptococcus pyogenes Infections caused bv streptococcus pyogenes1) Respiratory infectionso Sore throat is the most common of streptocococcal disease. It may be localised as tonsillitis as in older children and adults or it may involve the pharynx more diffusely (pharyngitis) as in younger children,o...
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temperment is a genitically related body biases in the modulation of conditioned behavioral responses to various external stimuli. there are 4 types of temperment namely novelty seeking reward dependence harm avoidance persistence this is a impoant question that is asked in entrance examinations Ref.Kaplon and sadock, ...
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ANSWER: (A) Involved in apoptosisREF: Robbins pathology 7th edition page 27-29Caspases are essential in cells for apoptosis, or programmed cell death, in development and most other stages of adult life, and have been termed "executioner" proteins for their roles in the cell Some Caspases are also required in the immune...
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Answer- C. Haemolytic disease of the newbornHemolytic disease of thefetus and newborn (HDFN), also known as alloimmune HDFN or erythroblastosis fetalis, is caused by the destruction of reil blood cells (RBCs) of the neonate or fetus by maternal IgG antibodies.
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Foamy appearance or frothy cytoplasm is a feature associated with the presence of lipid/mucinous material in the cell cytoplasm. It is seen in mucous secreting goblet cells or lipid phagocytizing macrophage eg Touton giant cell (but not in paneth cells). Paneth (zymogen) cells are rich in zinc, rough endoplasmic reticu...
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Decreased aldosterone causes metabolic acidosis + Hyponatremia Hyperkalemia Hypotension.
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Teeth and bones   Tetracyclines have chelating property. Calcium-tetracycline chelate gets deposited in developing teeth and bone. Given from mid pregnancy to 5  months of extrauterine life, tetracyclines affect the deciduous teeth.  Brown discolouration, ill-formed teeth which are more susceptible to caries are produc...
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Ans. is 'a' i.e., PPP Source of NADPH for lipogenesis NADPH is involved as donor of reducing equivalentse in both the reduction of 3-ketoacyl by 3 ketoacyl reductase and of 2,3- unsasturated acyl by enoyl reductase. The main source of NADPH for lipogenesis is the pentose phosphate pathway: PPP (Hexose monophosphate shu...
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Causes of hypocalcemia Hypoparathyroidism DiGeorge syndrome PTH receptor defect (pseudohypoparathyroidism) Magnesium deficiency Exogenous organic phosphate excess Vit D difecidecien
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Procaine belongs to ester group. Since Ester links are more prone for hydrolysis than amide links generally esters have a shoer duration of action. Other three are amide group. From padmaja 4th edition Page no 199
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Ans. is 'a' i.e., Zenker's diveiculum
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Hormonal therapy in Carcinoma in breast Ovarian suppression or ablation Bilateral oophorectomy. Medically by LHRH agonist (Goserelin, leuprolide) SERM: Tamoxifen and Raloxifen Aromatase Inhibitors Non-steroidal : Letrozole & Anastrazole Steroidal : Exmestane Anti-Estrogens Fulvestrant Progestins Megesterol & Medroxypro...
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Ans. is 'c' i.e., 90% of non familial cases are bilateral Pheochromocvtomao Pheochromocytoma is a neoplasm of chromaffin ceils which usually arise from adrenal medulla,o About 10% of these tumors arise at extraadrenal sites, where they are called paraganglioma :-o When pheochromacytomas arise at extra-adrenal site, the...
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Dry socket is also known as Sicca Dolorosa, alveolar osteitis, localized alveolar osteomyelitis, fibrinolytic alveolitis.
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Vanillyl Mandelic acid (V.M.A) is an end product of catecholamine metabolism and is used for screening for pheochromocytoma. In carcinoid syndrome, the 5HT derivative histamine results in flushing episodes. Neuroendocrine tumors along the GI tract use tryptophan as the source for serotonin production, which limits the ...
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Ans. is 'b' i.e., 3-4 cm The lower esophageal sphincter (LES) is a bundle of muscles at the low end of the esophagus, where it meets the stomach.When the LES is closed, it prevents acid and stomach contents from traveling backwards from the stomach.The LES muscles are not under voluntary control.Lower esophageal splinc...
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The respiratory rate is essentially unchanged, but tidal volume and resting minute ventilation increase significantly as pregnancy advances. The functional residual capacity and the residual volume are decreased as a consequence of the elevated diaphragm. Lung compliance is unaffected by pregnancy, but airway conductan...
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Odontoid fractures usually result from flexion forces. Odontoid fractures are classified as type I, II, or III. Type I fracture involves the tip only. Type II fracture passes through the base of the odontoid process. Type III fracture passes through the body of C2. Types II and III are considered unstable and should be...
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Amyloidosis of SpleenAmyloid deposition in the spleen, for some unknown reasons, may have one of the following two patterns:1. SAGO SPLEEN. The splenomegaly is not marked and cut surface shows characteristic translucent pale and waxy nodules resembling sago grains and hence the name.Microscopically, the amyloid deposit...
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The cervix protrudes into the vagina. The uterus is held in position within the pelvis by condensations of endopelvic fascia, which are called ligaments. These ligaments include the pubocervical, transverse cervical ligaments or Mackenrodt's ligaments or cardinal ligaments, and the uterosacral ligaments. Ref - BDC 6e v...
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C i.e. 7.33 CSF sugar is 2/3 of plasma sugarQ. So CSF/plasma glucose ratio is -. 0.6667. CSF pH is 7.33Q (less than plasma pH 7.4) and its pressure is maintained by its absorption at arachnoid villQ. Hypehyroidism cause decreased whereas, hypothyroidism/myxoedema is associated with increased CSF protein. Substance CSF ...
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Lead poisoning may occur in children or adults due to accidental or occupational ingestion. In children, the following are the main sources of lead poisoning:Chewing of lead-containing furniture items, toys or pencils.Eating of lead paint flakes from walls.In adults, the sources are as follows:Occupational exposure to ...
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Ans. is 'c' i.e. Ampulla of vater
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Focus on Dopamine Scientists probed fuher to see if they could link the brain's reward systems to a paicular set of chemical mechanisms. They soon found that blocking the neurotransmitter dopamine seems to reduce an animal's pleasure-seeking drives. For example, depleting dopamine in the brain causes animals to become ...
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Negri bodies are seen in the Pyramidal neurons within Ammon's horn of the Hippocampus and Purkinje cells in the cerebellar coex on postmoem of the rabied person.
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Hypotension is the most common acute complication of hemodialysis. It is paicularly common among patients with diabetes mellitus. The factors that appear to increase the risk of hypotension, are excessive ultrafiltration with inadequate compensatory vascular filling, impaired vasoactive or autonomic responses, osmolar ...
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CSOM is of Two Types
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Parietal skull fractures are more suggestive of accidental injury.
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The transmission of HIV from mother to infant has decreased in recent years, due in large part to perinatal administration of antiretroviral medications to the mother and a course of zidovudine to the exposed infant. Studies suggest that a better than 50% decrease in transmission can be seen with appropriate medication...
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Internal carotid beginning, course and termination it is a terminal branch of common carotid aery. It first runs through the neck ( cervical pa) then passes through the petrous bone ( petrous pa) then courses through the sinus ( cavernous pa) and lastly lies in relation to the brain ( cerebral pa). Area of distribution...
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Answer- C. 6 - 8 weeksThe half-life of an erythrocyte is typically 60 days, the level of glycated hemoglobin (HbA1c) reflects the mean blood glucose concentration over the preceding 6-8 weeks.
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Congenital Syphilis - Caused by Treponema pallidum. Congenital syphilis is a cause of hydrops fetalis, or stillbih due to fluid accumulation in the fetus. If the newborn survives, it can develop various abnormalities. Classic facial anomalies - Hutchinson's incisors Mulberry molars, Saddle nose Frontal bossing Sho maxi...
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Ans. is 'b' i.e., 1987 o The Mental Health Act was passed on 22nd May, 1987.
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Trigone is derived from mesoderm although bladder is endodermal in origin. Intermediate mesoderm forms the Genito urinary system. Endoderm forms the urogenital sinus which forms urinary bladder and urethra.
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Fractures commonly showing cubitus valgus deformity due to malunion : Fracture lateral condyle humerus Monteggia Fracture Dislocation Complications of lateral condylar humerus fractures Cubitus valgus Cubitus Pseudovirus (lateral spur) Tardy ulnar nerve palsy Osteonecrosis of the trochlea
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Cholangiocarcinoma is classified into two: 1.Intrahepatic 2.Extrahepatuc: which is divided into- Perihilar tumors: these are known as Klatskin tumors and are located at the junction of the right and left hepatic ducts forming the common hepatic duct. Distal bile duct tumors: they arise near the ampulla of Vater REF: GE...
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Ans. is 'a' i.e., Intraosseus cannulation Intraosseus transfusiono For patients in respiratory failure or shock, securing vascular access is crucial, along with establishing an airway and ensuring adequacy of breathing and ventilation. Peripheral intravenous catheter insertion is often difficult, if not impossible, in ...
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Rovsing's sign, Obturator sign and Psoas sign are seen in appendicitis. Positive Murphy's sign is seen in acute cholecystitis. It is an ultrasonographic sign in which there is an area of maximum tenderness directly under the probe. Rovsing's sign refers to pain in the right lower quadrant when palpatory pressure is exe...
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Ans is 'b' ie Mucosal folds below the carina
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In DCT: - The sympoer is NCC (Na+-Cl- cotranspoer) In the PCT, the apical membrane has Na+/H+-antipoer, which couples H+ secretion with the Na+ movement across the apical membrane. In the TAL of loop of Henle: - The sympoer NKCC moves 1 Na+, 1 K+, 2 Cl- through the apical membrane into the cell. In the late distal tubu...
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Ans. is a, i.e. Increased birth weightRef: Williams gynae 3rd/ed, p397Risk factors for PCOS in ad descent girls* Low birth weight* Premature adrenarche* Obesity with acanthosis nigricans* Atypical sexual precocity
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Ans. is 'b' i.e., Postganglionic sympathetic fibres except in sweat glandsNeurotransmitter in all preganglionic autonomic nerves (both sympathetic and parasympathetic) is acetylcholine (A CH)Neurotransmitter in all ganglia (both sympathetic and parasympathetic) is acetylcholine.Neurotransmitter in postganglionic parasy...
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The features of Arachnida which includes ticks, mites, scorpions and spiders etc are four pairs of legs, absence of wings and antennae. Their bodies are divided into cephalothorax and abdomen. Ref: Park's Textbook of Preventive Medicine, 20th Edition, Page 672.
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Ans. c. Intellectual disabilityRef: First Aid for the Psychiatry Clerkship 4th Ed; Page No-122-23Intellectual disability (ID, intellectual developmental disorder) replaces the term mental retardation (MR) as per US law (Rosas Law), with the intention of decreasing stigmatization.ID is characterized by severely impaired...
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Corneal hysteresis assesses the biomechanical strength of the cornea and is assessed by Dynamic Contour Tonometry(DCT). Dynamic contour tonometry (DCT) is a contin- uous (dynamic) and direct tonometric principle. It reads the IOP at the interface between the sensitive tonometer tip and the surface of the cornea. Ref kh...
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Ans. c (Excision of tumor [surgical removal) (Ref. Bailey and Love Surgery 25th/pg. 762)PLEOMORPHIC ADENOMA# Initially described as a 'mixed' salivary gland tumor# Accounts for 75% of parotid and 50% submandibular tumors# Believed to have both epithelial and mesothelial elements# Now appears to arise from ductal myoepi...
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Ans. is 'b' ie Avascular necrosis of hip "The femoral head is the commonest site of symptomatic osteonecrosis (avascular necrosis), mainly because of its peculiar blood supply which renders it vulnerable to ischemia.Non traumatic osteonecrosis is seen in association with infiltrative disorders of the marrow, Gaucher's ...
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Ans. is 'b* i.e., Negative correlation o This is a negative correlation. Le. when height increases the mosquitoes decrease,First read about these two related terms :-o Association - Association may be defined as the concurrence of two variables more often than would be expected by chance. That mean 2 variables exist si...
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Ans. b. Cytoplasmic membrane
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Ans. is 'a' i.e., Multiple sclerosis Treatment of multiple sclerosiso Multiple sclerosis is an autommune disease characterized by chronic inflammatory demylination that affects the CNS.o The most common course of the disease is the relapsing-remitting subtype, which is characterized by unpredictable acute attacks (rela...
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Ans. C i.e. p24 antigen. HIV infection is identified either by the detection of HIV-specific antibodies in serum or plasma or by demonstrating the presence of the virus by nucleic acid detection using polymerase chain reaction (PCR), p24 antigen testing or, rarely these days, by growing virus in cell culture. Antibody ...
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"Acute tonsillitis usually occurs as a component of a widespread acute bacterial pharyngitis, usually due to hemolytic streptococci. The tonsils are swollen red due to mucosal hyperaemia and partly covered by creamy acute inflammatory exudate (acute parenchymatous tonsillitis). Sometimes there are scattered, creamy yel...
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Initial Management of the Burned Airway Early Elective Intubation is safest Delay can make Intubation very difficult because of swelling Be ready to perform an Emergency Cricothyroidotomy if Intubation is delayed
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Inguinal canal- Posterior wall formation -        Medial 2/3- Conjoint tendon and reflected part of inguinal ligament -        Whole- Fascia transversalis, extraperitoneal connective tissue, parietal peritoneum.
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ROOTS OF OTIC GANGLION: Sensory root is by auriculotemporal nerve Sympathetic root is by sympathetic plexus around middle meningeal aery Secretomotor root is by lesser petrosal nerve from tympanic plexus formed by tympanic branch of cranial nerve IX Motor root is by a branch from nerve to medial pterygoid Ref BDC volum...
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The child has a form of galactosemia. The elevated galactose enters the lens of the eye, is reduced to galactitol, and is trapped. The difference in osmotic pressure across the lens of the eye leads to cataract formation. Galactose is phosphorylated by galactokinase to galactose-1-phosphate, which reacts with UDP-gluco...
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Clinical features Coeliac disease can present at any age. In infancy, it occurs after weaning on to cereals and typically presents with diarrhoea, malabsorption and failure to thrive. In older children, it may present with non-specific features, such as delayed growth. Features of malnutrition are found on examination ...
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Otoacoustic Emissions (OAEs) They are low intensity sounds produced by outer hair cells of a normal cochlea and can be elicited by a very sensitive microphone placed in the external ear canal and an analysis by a computer. Sound produced by outer hair cells travels in a reverse direction: Outer hair cells-basilar membr...
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Ans. (d) Granuloma formationRef: Robbiris pathology 9th ed. 197* Granuloma formation is characteristic of chronic granulomatous inflammation and is not seen in acute inflammation.* Vasodilation, increase in permeability, exudation, margination, rolling etc. are seen in acute inflammation.
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Transvaginal ultrasound Diagnosis of Ectopic pregnancy Pregnancy is definitely diagnosed by demonstrating intrauterine sac. - A normal intrauterine sac appears regular and well defined on ultrasound. So ectopic pregnancy can be diagnosed by demonstrating the absence of the intrauterine sac. In a woman in whom ectopic p...
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The role of vitamin K is in the post-translational modification i.e, gcarboxylation of glutamic acid residues in proteins such as : Coagulation factors : Factor II, VII, IX, X Protein C and S Osteocalcin Nephrocalcin Reference: Harpers illustrated biochemistry 30th edition
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Ans. a. Breast Imaging Repoing and Data System BIRADS stands for Breast Imaging Repoing and Data System BIRADS (Breast Imaging Repoing And Data System) Category Definition 0 Incomplete assessment, need additional imaging evaluationQ 1 Negative, routine mammogram in 1 year is recommendedQ 2 Benign findings, routine mamm...
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<p> - positron emission tomography is a functional diagnostic imaging technique, taking note of the fact that malignant cells have a greater glycolysis as ccompared to normal tissue. - it helps in staging , management and follow up of cancer growth. - it is now used in diagnosis of cancer in its early stage, detect its...
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Ans. D. Following Rifampicin ingestionHematuria is defined as the presence of 5 or more red blood cells (RBCs) per high-power field in 3 of 3 consecutive centrifuged specimens obtained at least 1 week apart. Hematuria can be either gross (i.e., overtly bloody, smoky, or tea- colored urine) or microscopic. However inges...
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Canal exploration: 8, 10 K file used.  In calcified canal exploration: 6 K file, C+ file, profinder.
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In non-primate mammals, end product of purine metabolism is allantoin due to presence of enzyme uricase. Uricase convees uric acid to allantoin. Humans lack the enzyme uricase. Therefore, end product of purine catabolism in humans is uric acid REF: Lippincott book of biochemistry 6th ed.
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Ans. is 'a' i.e., Trichophyton Hair perforation test . The hair perforation test consists of inoculating colonies of an organism into a dish containing a small amount of water, a few drops of yeast extract solution and some human hair. The dish is incubated at 300C and after 7 days, some of the hair are taken and are k...
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Yoke assembly system belongs to high pressure system of anaesthetic machine.
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(A) Spleen# Largest lymphatic organ in the human body is the spleen.> Primary function of the spleen is to purify the blood and store blood cells. It helps the immune system identify and combat foreign antibodies.> The spleen consists of white pulp and red pulp. The white pulp generates blood cells and synthesizes anti...
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Ref. The Short Textbook of Pediatrics. Pg 754 A fact based question. Answer 200
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Ref KDT 6 /e p606 Anticoagulants are the most mainstay for the treatment of pulmonary embolism Thrombolytic therapy is indicated bin massive pulmonary embolism with hemodymica instability and in hemodymically stable patients but with compromised right ventricular function
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Ans. is 'b' i.e., Crohn's Disease Features of CD In the affected segment, mesentric fat wraps around the bowel surface --> creeping fat o The intestinal wall is rubbery and thick, as a consequence of edema, inflammation, fibrosis, and hyperophy of the muscularis propria --> lumen is almost always narrowed --> string si...
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Predisposing factors for Black stones Hemolytic disorders(Heriditary spherocytosis, sickle cell anemia) Mechanical prosthetic hea valves Cirrhosis Gilbe's syndrome Cystic fibrosis Ileal disease or resection Brown stones Related to stasis and infection Gram negative bacteria (E.coli and Klebsiella) secretes beta-glucuro...
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Ans. (b) HyponatremiaRef: Bailey 26th Edition, page 1349* Most common electrolyte abnormality during TURP is HYPONATREMIA due to water intoxication.
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Pehes&; disease, the osteochondritis of the epiphysis of the head of the femur is the commonest osteochondritis.Maheswari 5e pg: 318
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C, i.e. D-glucose - Carbohydrate isomers that differ in configuration around only one carbon atom are called epimers. D-glucose and Dmannose are C2 epimers whereas D- glucose and D- galactose differ only at C4. However, D-mannose & D- galactose are not epimersQ as they differ at 2 carbons (2 & 4). Enantiomers (optical ...
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After pellets of gold are rolled, they may be conveniently stored in a gold foil box, which is divided into labeled sections for various sizes of pellets.  Cylinders of foil and selected sizes of other types of gold also may be stored in the box. Preferential contamination is suggested by placing a damp cotton pellet d...
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RA with Hepatitis B??? We are still not sure of the answer. Anti TNF-a drugs can be used in all of the conditions mentioned in the question. Anti TNF a the therapy in Hepatitis B For the treatment of HBV, Anti TNF- atherapy showed cases of fulminant HBV reactivation. But any HBV reactivation was treated success fully w...
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B. henselae is associated with Cat-scratch disease, bacillary angiomatosis, bacillary peliosis, bacteremia, endocarditis
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Ans: b (Atrial fibrillation) Ref: Davidson, 20th ed, p. 555This is a direct pick from Davidson.Cardiac arrest may be due to ventricular fibrillation, ventricular tachycardia, electromechanical dissociation or ventricular asystole.Cause of cardiac arrest1) VF and pulseless VT -- Most common and most easily treatable cau...
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Ans. is 'a' i.e., Staphylococcal pneumonia Staphylococcal pneumonia is the most common cause of (amongst all pneumonia) Pneumatoceles Pneumothorax Lung abscess Purulent pericarditis Empyema Other organisms commonly causing empyma --> Streptococcus pyogenes, Pneumococci
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Ans. b (Diamond-Blackfan syndrome) (Ref. Nelson Paediatrics 18th12047; Table 468-1)Diamond-Blackfan syndrome (DBS), also called congenital hypoplastic anemia, is a macrocytic pure red aplasia associated with several congenital anomalies such as short stature, webbed neck, cleft lip, shielded chest and triphalangeal thu...
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