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MC cause of peritonitis in adult male: Peptic ulcer perforation * The most common cause is a perforation of the abdominal viscus-most commonly, a perforated ulcer, may occur as a result of perforation of any pa of the bowel; other causes include a benign ulcer, a tumor, or trauma.* MC cause of peritonitis in adult male...
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Ans. is 'a' i.e., Increases cobalamin absorption o Intrinsic factor is a small glycoprotein secreted by the parietal cells of the gastric mucosa.lt is essential for vitamin B12 absorption.o Gastric acid and pepsin release the vitamin from protein binding in food and make it available to bind to cobalophilin, a binding ...
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Ans. (a) Diabetes mellitus(Ref: Robbins 9th/pg 1118)Most specific histological lesion in diabetic nephropathy (see chapter 18 Endocrine system) is Nodular glomerulosclerosis or Kimmelsteil -Wilson lesions
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Differential RNA processing decides whether an immunoglobulin will remain membrane bound or secreted. Ref: Textbook of biochemistry by DM Vasudevan3rd edn/page 354.
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Red line: Right ear Blue line: Left ear Continuous line: Air Conduction Dotted line: Bone conduction Ref: Dhingra; 6th Edition; pg no 30
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Ans. D. Bulbocavernosus reflexThe bulbocavernosus reflex is an oligosynaptic reflex mediated through the S2-S4 spinal cord segments that is elicited by electrical stimulation of the dorsal penis/clitoris nerves with the reflex response recorded from any pelvic floor muscles.The afferent paths of the bulbocavernosus ref...
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Chemotaxis is unidirectional locomotion of leukocytes towards the site of injury, oriented along a chemical gradient. This chemical gradient is created by substances called chemoattractants (chemotactic agents), which may be exogenous (bacterial products) or endogenous (C5a, LTB-4, IL-I, TNF, IL-8). C5a is the most pow...
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Early after the onset of acute cholecystitis, the plane of dissection may be facilitated because of early inflammatory response. Between the seventh and fourteenth day after admission, surgery may be extremely difficult because of resolving infection and adhesions. Where possible surgery should be avoided during this p...
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A recent development in the pharmacologic treatment of affective disorders, especially bipolar disorder, has been the use of anticonvulsant drugs. The first to be tried, carbamazepine (Tegretol) often is the next line of treatment for bipolar disorder for persons unresponsive to lithium therapy. Carbamazepine has vario...
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Blood Level: Normal folic acid level in serum is about 20 nanograms/ml and about 200 microgram/ml of packed cells. The level is measured by radioimmunoassay. Histidine load test or FIGLU excretion test: Histidine is normally metabolised to formimino glutamic acid (FIGLU) from which formimino group is removed by THFA. T...
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B i.e. Lepromin test Lepromin test has no diagnostic value; it has only prognostic significanceQ as it tells about cell mediated immunity & classify the type of disease. Lepromin test is most positive in TT because cell mediated immunity is least suppressedQ
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Subacute Granulomatous (de Quervain) thyroiditis: - Self-limited disease, probably secondary to viral infection & is characterized by presence of painful & granulomatous inflammation in thyroid. - It is MCC of tender thyroid - Lab findings : increased serum T4, decreased TSH, decreased radioiodine uptake - Early stages...
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Procaine is an ester linked local anaesthetic. Bupivacaine, Lignocaine and Mepivacaine are amide linked local anesthetics. Other ester linked anesthetics are cocaine, chloroprocaine, tetracine and benzocaine. Ref: Essentials of Medical Pharmacology By K D Tripathi, 5th Edition, Page 320.
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Ans. is 'b' i.e., Light chains . Bence jones proteins coagulate at 50degC but redissolve at 70degC. . Bence Jones proteins are light chains of immunoglobulins, so may occur as the Kappa or lambda forms. . Bence jones proteins are found typically in multiple myeloma. . In multiple myeloma patients, large amount of Bence...
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Subcutaneous implant
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Fallopian tube has no submucosa. It lies in upper margin of broad ligament. Epithelium is responsive to hormones.
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The roots of the brachial plexus are the anterior rami of spinal nerves Cs-T1. These five roots form the three trunks of the plexus. Each trunk divides into an anterior and a posterior division. The divisions form the three cords of the brachial plexus. The dorsal scapular nerve is a branch of the C, root. The supra sc...
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Answer-(a) DNA footprinting DNA footprinting- An in-vitro technique to find out protein binding regions on a DNA molecule. The technique is also called as DNAse I footprinting.Thousands of proteins (enzymes) are interacting with DNA in the nucleus for regulating activities like replication, transcription, translation e...
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Mallory-Denk bodies: These are usually present as clumped, amorphous, eosinophilic material in ballooned hepatocytes. They are made up of tangled skeins of intermediate filaments such as keratins 8 and 18 in complex with other proteins such as ubiquitin They are a nonspecific finding and can be found in patients with s...
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Median lobe of prostate
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Ans. C. Kartagener syndromea. Kartagener syndrome is the inheritable disorder of dextrocardia, infertility, chronic sinusitis (with the formation of nasal polyps), and bronchiectasis.b. Patients may also present with situs inversus.c. The disorder is due to a defect that causes the cilia within the respiratory tract ep...
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Thinking characterised by the ability to grasp the essentials of a whole, to break a whole into its pas, and to discern common propeies. To think symbolically. Ref: Synopsis of Psychiatry, 11e, pg 1407.
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Answer- D. PregnancyPregnancy is a relative contraindication for thrombolytic therapy in acute ST segment elevation myocardial infarction and not an absolute contraindication.Historv of any intracranial hemorrhagicHistory of ischemicl stroke within the preceriing thrse months, with the impoant exception of acute ischem...
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Ans. is 'a' i.e., Spheno-ethmoidal recess Part of lateral nasal wallOpeningsInferiorNasolacrimal ductMiddleFrontal sinus, Maxillary sinus. Anterior ethmoidal sinusSuperiorPosterior ethmoidal sinusSphenoethmoidal recessSphenoid sinus
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.neuroblastoma is the commonest abdominal tumor . it is the tumor of adrenal medulla.. clinical features-chilg presents with huge abdominal mass,in the groin which is non mobile.not moving with respiration. nodular surface,crosses the midline.dancing eye syndrome and opsomyoclonus racoon&;s eye sign is infra orbital ec...
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Genital ridge Friends, I am giving you a very impoant tabls. Many questions can be solvod trom lhis very table. Male and female derivatives of embryonic urogenital structures. Embryonic structures Derivatives Male Female Labioscrotal swelling Scrotumo Labia majorao Urogenilal folds Ventral aspect ot penis Labia minora ...
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Ans. is 'a' i.e., Drug concentration above which it appears in urine Renal Thresholdo The renal threshold is the concentration of a substance dissolved in the blood above which the kidneys begin to remove it into the urine. When the renal threshold of a substance is exceeded, reabsorption of the substance by the proxim...
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Bulbourethral glands are located posterior and lateral to the membranous poion of the urethra at the base of the penis, between the two layers of the fascia of the urogenital diaphragm, in the deep perineal pouch. They are enclosed by transverse fibers of the sphincter urethrae membranaceae muscle. Ref - BDC 6e vol2 pg...
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In the third phase grey hepatisation, no new erythrocytes are extravasating, and those already present have been lysed and degraded.  The neutrophil is the predominant cell, fibrin deposition is abundant, and bacteria have disappeared. This phase corresponds with successful containment of the infection and improvement ...
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Ans. Warm moist atmosphere
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B ref: Ahuja, 4th/e p. 118 and 5th/e p. 130
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Surface discolorations because of fluorosis can also be removed by microabrasion, if the discoloration is within 0.2 to 0.3 mm removal depth limit. In 1984, McCloskey reported the use of 18% HCI swabbed on teeth for the removal of superficial fluorosis stains.  Subsequently, in 1986, Croll modified the technique to inc...
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Adrenalin and histamine and glucagon, insulin are physiological antagonists Physiological antagonism - opp effect on the same physiological system by two drugs glucagon increases blood glucose, insulin decreases- blood glucose adrenaline- bronchodilatation histamine- broncho constriction Ref KD Tripathi 8th ed.
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Ans. (c) Removal of fragments of bone Missile injury management*Wound excision and leave wound opened* Foreign materials to be removed.* Excise the skin edge around the entry and exit point* Unhealthy dead muscle must be removed.* Bone shattered by high energy transfer may still have attachment to periosteum or muscle....
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Adequate breathing ensures that sufficiently oxygenated blood is in circulation. Breathing is assessed by the Look-Listen feel technique. The clinician observes the rise and fall of the chest and at the same time feels and listens to the breath sounds. If the child is breathing adequately, then maintain the head tilt c...
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Ans. is 'c' pulmonary T.B. (Ref. CMDT, 2002/e, p. 310; API, 6/e, p. 244; Harrison, 16/e, p 961 (15/e, p. 1030))The history and tuberculin test strongly suggests the diagnosis of T.B.Do not get confused by negative sputum cytology because negative sputum cytology does not rule out pulmonary tuberculosis."Sputum cytology...
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Axillary nerve
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Fish Tank Granuloma * Caused by atypical mycobacterial infection * Recreational or occupational exposure to contaminated freshwater or saltwater * Affects elbows, knees, feet, knuckles or fingers * Often single lump which causes crusty sore or abscess * Other lumps on course of lymphatic drainage * More widespread if i...
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Aspiration is prevented
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When even a relatively minor noxious stimulus is applied to the skin it may activate autonomic neurons and produce evacuation of the bladder and rectum, sweating, pallor, and bp swings in addition to withdrawal response. This distressing mass reflex can sometimes be used to give paraplegic patients a degree of bladder ...
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ANS. BEmergency contraception:1. Yuzpe method (within 72 hours: High dose OCP 2 + 2 (12 hours apart) or low dose OCP 4 + 4 (12 hours apart).2. LNG 0.75 mg 1 tab immediately, 2nd tab after 12 hours.3. Mifepristone (RU 486).4. Ulipristal 30 mg tab--5 days.5. Copper-TIUDImages of copper containing IUDCU-T380AImage of Mire...
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ATP Generating Steps in TCA Cycle - There are 3 NADH molecules generated during one cycle, each of them will give rise to 2 1/2 ATPs on oxidation by electron transpo chain (ETC); so altogether they will give 3 x 2 1/2 = 7 1/2 (7.5) high energy phosphates. The FADH2 will generate 1 1/2 molecules of ATP. In addition, one...
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Parasites entering through feco-oral route:ProtozoaTrematodeCestodeNematodeHistolyticaGiardia lamblia Balantidium coli Sarcocystis hominids Sarcocystis suihominis Isospora Cyclospora Cryptosporidium parvum MicrosporidiaFasciola hepatica Fasciolopsis buski Clonorchis sinensis Opisthorchis felineusParagonimus westermaniG...
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Ans. D i.e. Graze or impact injury
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Ans. D. SuccinateVitamin C plays an important role as a co enzyme in the hydroxylation of Proline. The reaction is dependent on proline and requires vitamin C, alpha ketoglutarate, molecular O2 and Fe2+
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Ans. is 'a' i.e.,Oral paracetamol for 2 - 3 days Shoulder tip pain after laproscopic surgery:* The patient should be warned about this preoperatively and told that the pain is referred from the diaphragm and not due to a local problem in the shoulders.* It can be at its worst 24 hours after the operation.* It usually s...
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Okazaki fragments are sho segment of DNA synthesised on lagging strand, during the process of replication of a double stranded DNA. Ref: Biochemistry By Mary K. Campbell, Shawn O. Farrell, 7th Edition, Pages 258, 275; Harper Textbook of Biochemistry, 27th Edition, Pages 335-37; Lewin's Genes X By Benjamin Lewin, Page 3...
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Leukemia is most common radiation induced cancer. Others: Thyroid, Breast Carcinoma
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The patient has diabetes-induced nephropathy. As the kidneys lose function, the ability of creatinine to be absorbed into the urine decreases, and its excretion would be low. Creatine is synthesized from glycine, arginine, and SAM. In muscle, creatine is converted to creatine phosphate, which is nonenzymatically cycliz...
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Ans. is 'b' i.e., 2 ASA GradePatient conditionASA 1Normal healthy patient (no physical or mental illness)ASA 2Mild systemic disease not limiting functional activity(mild heart disease, DM, Mild hypertension, Anemia, Old age, obesity, mild chronic bronchitis)ASA 3Severe systemic disease that limits activity but not inca...
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UNITS OF RADIATION Physical quantity S.I. Unit Non S.I. Unit Conversion Radioactivity Becqueral (Bq) Curie (Ci) 1 Ci = 3.7 X 1010 Bq Absorbed dose Gray (Gy) Rad 1 Gy = 100 rads 1 rad = 0.01 gy Dose equivalent Sieve (SV) Rem 1 SV = 100 rem 1 Rem = 0.01 Sv Exposure coulomb/kg Roentgen 1R= 2.58 x 10-4coulomb/kg of air
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The most important cause of bulging fissure is klebsiella pneumonia. Other causes are legionella pneumonia, streptococcal pneumonia, TB, Yersinia pestis, lung abscess, carcinoma bronchus
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Splenic aery itself is not an end aery - splenic branches of splenic aery are end aeries. Splenic branches do not have an anastomosis once they enter the substance of spleen. Splenic aery branches to stomach and pancreas, do anastomose within the substance of the respective organ (not end aeries). An end aery (or termi...
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Ans. is 'd' i.e., Bronchiolitis
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All the given drugs are used for neuromuscular blockade reversal, However neostigmine is the most commonly used one.
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Ans. Heteronymous
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Answer is A (Cerebellum) Hemangioblastomas associated with Von-Hippel-Lindau Disease are most commonly seen in the cerebellum. The hallmark lesion of Von-Hippel-Lindau (VHL) disease is the hemangioblastoma. These are most commonly seen in the cerebellum but occasionally seen in the medulla oblongata (most common brains...
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Lupus vulgaris is the most common type of cutaneous TB. Presence of apple jelly nodules at the edge of a plaque. Apple jelly nodules on diascopy- erythematous lesions will turn from pink to golden brown. They do not exhibit this color on Indian skin. In European cases the lesions occur on face paicularly about the nose...
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HDL The HDL particles are referred to as scavengers because their primary role is to remove free (unesterified) cholesterol from the extrahepatic tissues. HDL particles transport cholesterol from extrahepatic tissues to liver (i.e. reverse cholesterol transport) which is then excreted through bile.
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Serological tests are the most sensitive and specific tests; includes Immunoblast test, arcs test, ELISA and indirect hemagglutination tests. "The immunoblast test, where available, is the test of choice." - CMDT, 2005, p 1463. Casoni's test - Intradennal injection of 0.2 ml of fresh sterile hydatid fluid produces a wh...
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Various strains of the human papilloma virus (HPV, notably types 16, 18, 31, 33, 35, and 39) have been implicated as causing a variety of genital lesions, including genital was, cervical dysplasia, cervical cancer, vaginal dysplasia, vaginal cancer, and penile cancer. The koilocyte is the term used to describe the char...
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Retinoblastomas are the most common intraocular neoplasm found in childhood and with modern treatment modalities, are, in most cases, curable. On imaging, they are generally characterized by a heterogeneous retinal mass with calcifications, necrotic components and increased vascularization on Doppler ultrasound/enhance...
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The left umbilical vein becomes the round ligament of the liver after bih. The right umbilical vein did not leave a fibrous remnant because it was degenerated during the early embryonic period. The ductus venosus forms the ligamentum venosum; the ductus aeriosus forms the ligamentum aeriosum; Umbilical aery forms the m...
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Ans. is a i.e. Stage lb Ca cervix Radiotherapy is recommended in advanced stages of Ca cervix i.e. stage IIB onwards.deg Brachytherapy is commonly used. For larger tumours initially external radiation then brachytherapy is given In small tumours brachytherapy is given first followed by external radiation. For stage IB ...
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Imiquimod is an immune response modifier shown to be effective in the topical treatment of external genital and perianal was Ref: Katzung 11th edition Chapter 49.
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In carbon monoxide poisoning, the colour of post moem staining is cherry-red. In poisoning by nitrites, potassium chlorate, potassium bicarbonate, nitrobenzene, acetanilide, bromates, and aniline the colour is chocolate brown. In asphyxia, the colour of the stains is deeply bluish-violet or purple. A bright pink colour...
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Ans. is 'a' ie. Ruptured typhoid ulcer The clue to this answer is presence of this clinical sign in the pt. --) Obliteration of liver dullness. Obliteration of liver dullness : Right mid-axillary line is percussed from above downwoards. The percussion note will be resonant in the upper pa of the mid-axillary line. At t...
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5-nucleotidase is a marker in the mitochondria It cleaves 5 - nucleotides Ref:Guyton and Hall textbook of medical physiology 12th edition ,pag number: 20,21,22
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Doxorubicin an antitumor antibiotic is highly cardiotoxic. It causes acute cardiotoxicity in the form of atrial and ventricular dysrythmias and cumulative doses more than 550 mg/m2 is associated with a 10% incidence of chronic cardiomyopathy. Cardiotoxicity is related to the iron catalyzed oxidation and reduction of do...
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Malignant glaucoma occurs following an iridectomy, filtering surgery (Trebaculectomy) or laser irodotomy. It may also occur after cataract surgery, capsulotomy or even spontaneously.
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Division of distribution :     No of Intercept Divides into Testile 2 3 equal parts Quartile 3 4 equal parts Pentile 4 5 equal parts Octile 7 8 equal parts Centile 99 100 equal parts
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Compound fracture Compound fracture also called open fracture, in which fracture communicates with the external environment, i.e., overlying soft tissue coverage (skin and muscles) is breached. Open fractures are typically caused by high energy injuries such as car crashes, falls, or sports injuries. Gustila and Ander...
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This intrinsic ability of the hea to adapt to increasing volumes of inflowing blood is called the frank starling mechanism. Basically, the Frank-Starling mechanism means that the greater the hea muscle is stretched during filling, the greater is the force of contraction and the greater the quantity of blood pumped into...
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OCPS predispose Fibromuscular dysplasia affects mainly medium and large aeries. Sometimes alteration of the normal normal structure of the aerial wall gives rise to true aneurysms. There is also associated irregular hyperplasia. Muir's Textbook of pathology Edited by JR Anderson, 12 th edition, page no 14.36 Answer is ...
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Pseudomonas aeruginosa species, in particular, colonize the lower respiratory tract, first intermittently and then chronically.
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The common fibula (peroneal) nerve divides into the superficial fibula (peroneal) nerve, which supplies the fibula (peroneal) compartment, and the deep fibula (peroneal) nerve, which supplies the extensor compartment of the leg. This injury may occur because of a fracture of the proximal fibula or because of compressio...
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Anterior Horn of Medial Meniscus is the most anterior structure attached on the Intercondylar Area on the Superior Surface of Tibia. fig:- structure attached on the Intercondylar Area of Tibia. mnemonicfor remembering ligaments anterior to posterior-"Medical College Lucknow, Lucknow Medical College"
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Ans. (b) Superior obliqueRef: Grays Anatomy 41st Ed; Page No- 232* Superior oblique muscles supplied by trochlear nerve.* The marked nerve is Oculomotor Nerve.* Oculomotor Nerve emerges at the midbrain on the medial side of the crus of the cerebral peduncle and passes between the superior cerebellar and posterior cereb...
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Ans. is 'c' i.e., Anhidrosis Sympathectomy is used for the treatment of hyperhydrosis and would worsen anhydrosis rather than treating it.
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Ans. is 'b' i.e., Catalase test(Ref: Ananthanarayan, 9th/e, p. 200 and 8th/e, p. 196)* Coagulase test is used to differentiate the different species of staphylococci (staph, aureus, staph, epidermidis).* Catalase test is used to differentiate staphylococci from streptococci.* Coagulase test cannot be used to differenti...
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Herpes viruses replicate in the host cell nucleus, and both replication and assembly occur in the nucleus. The herpes virus encodes for several glycoproteins that facilitate viral attachment, fusion, and immune evasion.  The virus buds from nuclear membrane and is released by exocytosis and cell lysis. Parija SC. Text...
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Ans. is 'b' i.e., Hyaline membrane disease (HMD)
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Ans. is 'a' i.e., Plane o There are two types of atlanto-axial joints, both of which are synovial joints - i) One median atlanto-axial joint - Pivot joint. ii) Two lateral atlanto-axial joints - Plane synovial joint (flat joint).
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Ans. is 'a' i.e. Infancy Campbell's Urology writes - "Definitive treatment of an undescended testis should take place between 6 and 12 months of age. Because spontaneous descent occurs in most boys by 3 months of age and uncommonly thereafter, earlier interventions should be considered in order to theoretically prevent...
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Ans. is. b. Beta lysin
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Ans. is 'a' i.e., Stratum malpighi
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The area under Normal curve with ± 1 SD is 0.68.
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C i.e. Tachycardia Sinus tachycardia is most commonly occurring arrhythmia in the perioperative period.
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D i.e. ECT
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Estrogens are the principal medications used to relieve hot flushes. Estrogen blocks both perceived symptoms and physiological changes. Ref: Shaw's Textbook of Gynaecology, 12th Edition, Page 43 ; Current Obs and Gynae Diagnosis and Treatment 9th Edition, Page 1024
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Ans. is a, i.e. Stage IAs discussed in chapter 7 of the book, first stage of labor is from the time when a female starts perceiving true labor pains and uptil 10 cm of dilatation.
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Answer is D (None -- All are seen): Cushing's syndrome may be associated with all features mentioned in the question.
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Answer is C (Water deprivation test is required) : Diagnosis of diabetes insipidus often requires a water deprivation test. Water deprivation test is used to establish the diagnosis of diabetes insipidus and to differentiate Central and Nephrogenic forms of Diabetes Insipidus. Patients with diabetes insipidus have a no...
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Multiple papilloma Although multiple laryngeal papillomas are a rare laryngeal disease they are the most common laryngeal tumors in childhood. They may be present at bih but more commonly they arise around the age of 2 years. Cause is unknown but ceain viruses have been blamed. At laryngoscopy the papilloma look like b...
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ANSWER: (B) AtracuriumREF: Lee synopsis of anesthesia 12th e p. 215Repeat in December 2011Muscle relaxantRoute of eliminationPancuronium , Vecuronium , RapacuroniumLiverVecuronium , RocuroniumBiliarySch , MivacuriumPseudocholinesteraseGallamine , MetocurineRenalAtracurium, cis-atracuriumHoffman's elimination Obtain AMP...
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Various structural components of Streptococcus pyogenes exhibit antigenic cross-reaction with different tissues of the human body. Antigenic relationships have been demonstrated between capsular hyaluronic acid and human synol fluid, cell wall protein and myocardium, group A carbohydrates and cardiac valves, cytoplasmi...
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Barbiturates such as amobarbital inhibit electron transpo Complex I by blocking the transfer from Fe-S to Q. At sufficient dosage, they are fatal in vivo. Reference: Harper; 30th edition; Page no: 132
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BICEPS BRACHII:-Origin: Two heads-Long head-supraglenoid tubercle of scapula and glenoid labrum.Sho head-coracoid process of scapula.Inseion:-posterior rough pa of radial tuberosity Nerve supply:-musculocutaneous nerve.Action: supination of forearm when elbow is flexed.Flexion of forearm when elbow is extended.Biceps r...
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Ref:Park's Text book of Preventive and Social Medicine 25th ed
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The majority of nephrons are coical, with glomeruli located in the mid-to-outer coex. Fewer nephrons are juxtamedullary, with glomeruli at the boundary of the coex and outer medulla. Coical nephrons have sho loops of Henle, whereas juxtamedullary nephrons have long loops of Henle. Ref: George, A.L., Neilson E.G. (2012)...
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