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The prophylactic blood level of Lithium is 0.5 - 0.8 mEq/L.
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(C) FSH # Pituitary gland divided into anterior and posterior:> From Anterior lobe: TSH, ACTH, FSH, LH, GH, Prolactin, B-Lipotropin> From Intermediate lobe: Melanocyte stimulating hormone> From Posterior Lobe: Vasopressin, Oxytocin
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During this procedure, areas which can be palpated are: the bulb of the penis, the urogeital diaphram-, the annorectal ring, and other nearby anatomical landmarks. However, structures like the ureter(the two tubes that run from each kidney to the urinary bladder), and the urethra (which, in a male, is divided into thre...
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Ans: c (CMV) Ref: Harrison, 16th ed, p. 1119Most common ocular infection in HIV - CMV retinitisMost common ocular lesion in HIV - HIV microvasculopathyMost common ocular neoplasm in HIV - Kaposi sarcomaEarliest/ most common abnormal/ most consistent finding in HIV - cotton wool spots
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Cirsoid aneurysms are rare aerio-venous fistulas of the scalp. They are usually congenital in aetiology. In 90% of the patients, the superficial temporal aery is the main supply to the fistula ref - pubmed.com <a href=" <p>
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It is a secondary mode of prevention. Primary prevention:To avoid occurrence of disease. Secondary prevention:To diagnose and treat existent disease in early stages before it causes significant morbidity Teiary prevention:To reduce negative impact of extant disease by restoring function and reducing disease-related com...
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A reduction in the number of granulocytes in blood is known as neutropenia or, when severe, agranulocytosis. Neutropenic persons are susceptible to severe, potentially fatal bacterial and fungal infections.  The risk of infection rises sharply as the neutrophil count falls below 500 cells/μL. Kumar V, Abbas AK, Aster ...
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Bell's palsy ■ The most common form of facial paralysis is Bells palsy. Bell’s palsy is idiopathic palsy of facial nerve. Clinical Manifestations ■ The onset of Bell’s palsy is fairly abrupt, maximal weakness being attained by 48 h as a general rule. ■ Pain behind the ear may precede the paralysis for a day or two. ■ T...
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Harshmohan textbook of pathology 7th edition. Familial retinoblastoma comprises 40% of cases and may be bilateral . In this cases all somatic cells inherit one mutant RBgene from a carrier parent. Later during life the other mutational event of 2nd allele affecting the somatic cells occurs. This forms the basis of two ...
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Ans. is 'b' i.e. Sheets of atypical plasma cells Age of the patient along with cystic, circumscribed punched out X-ray appearance suggests multiple myelomaMultiple myeloma most often presents as multifocal destructive bone tumours composed of plasma cells throughout the skeletal system.The bone lesions appear radiograp...
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Monitoring of Neuromuscular block Done by nerve stimulator Different stimulation - Single Twitch Tetanus Train of four stimulus (most common) Double burst stimulation Post - tetanic count Nerves used - ulnar nerve (most common) (Adductor pollicis muscle ) Facial nerve Posterior tibial nerve External peroneal nerve Resp...
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Teriparatide stimulates osteobalsts and hence contraindicated in Osteosarcoma and Paget's disease.
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The most common clinical feature is headaches due to paroxysmal hypeension. The mnemonic to remember triad for suspecting pheochromocytoma is PHD- Palpitations, Hypeension,Hypercalcemia Diaphoresis. Note: Remember it is a mnemonic and does not imply that most common feature is palpitations.
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Ans. Judge
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Ans. (a) AscitesRef: Bailey & Love 26th ed. / 980* A peritoneo-venous shunt (also called Denver shunt) is a shunt which drains peritoneal fluid from the peritoneum into veins, usually the internal jugular vein or the superiorvena cava.* It is sometimes used in patients with refractory ascites.* It is a long tube with a...
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Azithromycin This new azalide congener of erythromycin has an expanded spectrum, improved pharmacokinetics, better tolerability and drug interaction profiles. It is more active than other macrolides against H. influenzae, but less active against gram-positive cocci. High activity is exeed on respiratory pathogens-Mycop...
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Ans. (C) (Rifampicin 450 mg + Clofazimine 150 mg) once monthly + Dapsone 50 mg daily + Clofazimine 50 mg alternate day(Ref: National Leprosy Eradication programme)This is a case of multibacillary leprosy. The multi drug therapy for in adults (15 years or above) is Rifampicin 600 mg plus clofazimine 300 mg once monthly ...
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Ans. (d) They may be associated with InsulinomasRef: Sabiston 20th edition Page 954* Zollinger Ellison syndrome is a manifestation of Gastrinoma* Secretin Stimulation test - is used a provocative test in cases of borderline elevation of Gastrin* ZES is associated with unusual location of ulcers like in Jejunum.
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Ans. a. Ascending LOH
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Abundance of acidfast bacilli rules out indeterminate and Tuberculoid leprosy. The choice is between lepromatous leprosy and borderline lepromatous leprosy. Hypoaesthesia points towards borderline lepromatous as sensation are not lost in lepromatous leprosy.
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Ans. A: Making endometrium unreceptive There are 2 categories of intrauterine contraceptive devices: Ine and copper -based devices, and Hormonally-based devices that work by releasing a progestogen. Most non-hormonal IUDs have a plastic T-shaped frame that is wound around with pure electrolytic copper wire and/or has c...
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Hyaluronidase is an enzyme that breaks down intracellular cement. It is added to LA to speed both the onset of anesthesia and the area of anesthesia especially in inferior alveolar nerve block.
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Criticalangle for the cornea-air interface is approximately 46 degrees. Total internal reflection prevents direct visualization of ang le in nearly all eyes. Ref khurana 6/e
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The wall of the vagina from the lumen outwards consists firstly of the mucosa of non keratinized stratified squamous epithelium with an underlying lamina propria of connective tissue, secondly a layer of smooth muscle with bundles of circular fibers internal to longitudinal fibers, and thirdly an outer layer of connect...
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* Extremities are warm to touch and full peripheral pulses. (WARM SHOCK) Option C- No survival advantage for the patients Option D- Already the patient is afebrile, so no point in checking the sensitivity of bacteria to antibiotics. Patient has a condition k/a DISTRIBUTIVE SHOCK Hydrocoisone is given in this case. * Hy...
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Ans. is 'a' i.e., Panic attack * Sudden onset of breathlessness, anxiety, palpitation and feeling of impending doom suggest the diagnosis of panic attack (severe anxiety)* A panic attack has following characteristics: -A. Discrete episode of intense fearB. Abrupt onset (sudden onset)C. Reaches as maximum within few min...
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Ans. Foreign body retained is the fornix
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In HIV the patient has to visit ICTC (Integrated Counselling and Testing Centre); Where a private counselling session is done. It holds valid for both pre-test and post-test counselling.
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Ans. a (Diarrhea) (Ref. H - 18th/pg. ch. 47)ANION GAP# The anion gap may be calculated by using (sodium + potassium) - (bicarbonate + chloride)# Normal =10-12 mmol/L# Causes of a normal anion gap or hyperchloraemic metabolic acidosis- Gastrointestinal bicarbonate loss: diarrhea, ureterosigmoidostomy, fistula- Renal tub...
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Mineralocoicoid excess increases net acid excretion and may result in metabolic alkalosis, which may be worsened by associated K+ deficiency. ECFV expansion from salt retention causes hypeension. The kaliuresis persists because of mineralocoicoid excess and distal Na+ absorption causing enhanced K+ excretion, continued...
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Ans. is 'b' i.e., A pateint who returns sputum postive which was curved by previous treatment Some definitions of tuberculosis cases and treatment Case of tuberculosis : A patient in whom tuberculosis has been confirmed by bacteriology or diagnosed by a clinician. Sputum smear examination - Laboratory technique to scre...
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The gastrocolic reflex or gastrocolic response is one of a number of physiological reflexes controlling the motility, or peristalsis, of the gastrointestinal tract. Ref: guyton and hall textbook of medical physiology 12 edition:443,444,445
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IgA nephropathy may occur following an episode of mucus membrane infection of the respiratory or gastrointestinal tract. Genetically susceptible individuals show increased amounts of IgA production following a viral or bacterial infection of the mucous membrane. Circulating IgA containing immune complexes are formed wh...
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46XX chromosomal pattern In a female most common cause of ambiguous sex is congenital adrenal hyperplasia. Intact cases of ambiguity of sex, detected at bih are due to adrenogenital syndrome (congenital adrenal hyperplasia) unless proved otherwise. Congenital adrenal hyperplasia (Very Imp.): It is an Autosomal Recessiv...
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Stem memory TSCM cells, like naive cells, are CD45RO-, CCR7+, CD45RA+, CD62L+ (L-selectin), CD27+, CD28+ and IL-7Ra+, but they also express large amounts of CD95, IL-2Rb, CXCR3, and LFA-1, and show numerous functional attributes distinctive of memory cells Reff: www.mayoclinic.com
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Ipra and tiotropium bromide are m3 receptor blockers more selective for bronchial muscle causing bronchial dilatation, so used in bronchial asthma and COPD M3 receptors are present on bronchial smooth muscle Ref: KDT 6th ed pg 113
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The musculocutaneous nerve arises from the lateral cord of the brachial plexus, opposite the lower border of the pectoralis major, its fibers being derived from C5, C6 and C7. In its course through the arm it innervates the coracobrachialis, biceps brachii, and the greater pa of the brachialis.
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Narcolepsy is characterized by bouts of sudden sleep each lasting for 10-30 minutes occurring during the daytime. Age of onset is between 10-20 years. Accessory symptoms in Narcolepsy are cataplexy, hypnagogic hallucination, sleep paralysis.
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Answer is C (Urinary A/C Ratio in a spot voided sample) The preferred method to establish microalbuminuria is to determine Albuma / Creatinine Ratio (A/C Ratio) in a spot voided urine sample. `The presence of albumin in the urine in the range of microalbuminuria is best determined by a urinary A /C Ratio in a spot void...
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Volkmann's ischaemia is an ischemic injury to the muscles and nerves of the flexor compament of the forearm. This occurs due to the occlusion of the brachial aery following a supracondylar fracture. The muscles supplied by the anterior interosseous aery are most susceptible to ischemic damage because this aery is an en...
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(Refer: Ganong's Review of Medical Physiology 24thedition, pg no: 483-484)
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Gartners duct cyst lies in anterolateral wall of vagina.
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Ans. a. Hypothalamic hamaoma Uncontrollable laughing and precocious pubey are suggestive of hypothalamic hamaoma. Hypothalamic Hamaoma Central precocious pubey staing before the age 3 years is often due to hypothalamic hamaomaQ . Seizures, especially laughing spells (gelastic seizures)deg are seen in children with hypo...
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Primary prevention aims at preventing the progression of risk factors to disease. It includes health promotion and specific protection. Immunization comes under specific protection. Ref : Park&;s Textbook of Preventive and Social Medicine; 23rd edition - Pgno. 42
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A,B,C All Correct
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Answer is A (Size of stone less than 15mm) Medical therapy for gall bladder stone is amenable for stones < 15 mm (preferably Prerequisites for medical therapy : Gall bladder should he functioning Stones should be radiolucent Size should be small preferably < 15 mm Q -Harrison 14'h (<10n/in-Harrison 16th) Stones should ...
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Ans. is 'a' i.e., Study of drug movement in the body Pharmakokinetics Pharmakokinetics is the quantitative study of drug movement, in through and out of the body. That means, it is the study of the effect of body on the drug. So, it is also known as ADME study as it deals with Absorption, Distribution, Metabolism and E...
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The axial length of the eyeball at bih 70% of an adult eye. Anteroposterior diameter is 24 mm in adult & Anteroposterior diameter of the eyeball is about 16.5 mm at bih (70% of the adult size which is attained by 7-8 years). Reference : A K KHURANA OPHTHALMOLOGY, Edition4, Page-11
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Lubiprostone :- selectively stimulates type 2 chloride channels in epithelial cells thereby causing an efflux of chloride into the intestinal lumen. - The resultant fluid secretion into the gastrointestinal lumen provides a bolus effect that softens stool, increases intestinal transit, and improves symptoms of constipa...
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Buccal frenum of maxilla contains levator anguli oris (caninus), buccinator and orbicularis oris. Buccal frenum of mandible contains triangularis or depressor anguli oris.
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Ans. is 'c' i.e., Bacterial surface polysaccharide o There are four pathways of complement system1) The classical activation pathway activated by antigen / antibody immune complexes.2) The mannose - binding lectin activation pathway activated by microbes with mannose terminal groups.3) The alternative activation pathwa...
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• Ischemic time for digits is upto 8 hours. • Ischemic time for extremities is 4-6 hours. • Organ containing bag should be placed in a solution of saline with ice.
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Wide excision REF: Devita 8th ed chapter 45 Aggressive fibromatosis is a rare condition marked by the presence of desmoid tumors, which are benign, slow-growing tumors without any metastaticpotential. However, Aggressive Fibromatosis is locally aggressive. Despite their benign nature, they can damage nearby structures ...
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8 essential components of primary health care are1)Education concerning prevailing health problems and the methods of preventing and controlling them2)Promotion of food supply and proper nutrition3)An adequate supply of safe water and basic sanitation4)Maternal and child health care, including family planning5)Immuniza...
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Ans. (b) P. aeroginosa Etiology of bacteremla associated with IV catheters Staph. epidermidis 85% S. aureus 7% Candida albicans 3% Enterococcus 2% Others - E. coli - Keibsieila - P. aerqinosa - Viridans streptococci 3%
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The silver-copper eutectic  alloy may be classified as the 3rd generation amalgam. Reference: Marzouk Operative dentistry, pg-106
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In infants with scabies the symptoms are itch or pruritus which is intense at night or nap-time. It can be so severe that the child can be so irritable and even refuse to eat. The characteristic lesions are burrows but they are not commonly seen. The papular, pruritic rash is most pronounced around abdomen, lower poion...
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Oligodendrocytes are the myelin forming cells of the cns One cell can myelinate 30 neurons Ref:Guyton and Hall textbook of medical physiology 12th edition,page number:72,73
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A i.e.Preoptic nucleus - Sexual behavior is integrated in anterior-ventral hypothalamusQ; plus piriform coex (in males only) - Ganong - Sexual drive can be stimulated from several areas of hypothalamus, especially the most anterior and most posterior poions of hypothalamusQ (Guyton) - Medial preoptic area (MPOA) or the...
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Ans. is 'b' i.e., Stricture of CBD Routes of infection to liverAlong the bile ducts (MC)Stone impacted in CBDStricture of CBD - benign, malignantCryptogenicVia the portal veinVia the hepatic arteryBy direct extensionFrom a subdiaphragmatic abscessFrom an empyema in chestFrom suppuratative cholecystitisFrom perinephric ...
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Ref - researchgate.net
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Ans. is 'b' i.e., Mitochondria o Outer mitochondrial membrane has protein to lipid ratio of 1.1.
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Tc-99m labellee rbc is used in assessment of GI bleeding .
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Ans. (b) Specific protectionRef : K. Park 23rd ed. / 41, 370-73* Iodised salt is given in an area which has risk of developing goiter. This is a primary level of prevention done by specific protection.* Primordial prevention is done before the emergence of risk factor.
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Ans. is 'b' i.e., SH groups in the enzyme o Tolerance develops to hemodynamic and antiischaemic effects of nitrates if they are continuously present in the body. No significant tolerance develops when nitrates are used intermittently. However; significant tolerance develops when nitrates are used continuously. This mec...
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MECHANISM OF FLUOROQUINOLONES (FQ) In gram negative bacteria, FQ inhibit DNA gyrase by binding to its A subunit and interfere with cutting and resealing function. In gram positive bacteria, FQ inhibit similar enzyme DNA topoisomerase IV.
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Response to treatment is the most impoant prognostic marker in ALL. Leucocyte count> 50000/ul Poor prognosis Hyperploidy Favorable prognostic factor Response to treatment Remission status at 14 days of chemotherapy is best guide to prognosis. Organomegaly Poor prognosis. Lymph node, liver, spleen and testis enlargement...
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Ans. is 'd' i.e., Migraine * Meniere's disease is a disorder of the inner ear which is characterized byi) Episodes of vertigoii) Tinnitus (ringing in the ears)iii) Fluctuating sensorineural hearing lossiv) Feeling of fullness or pressure in ear (aural fullness)* A typical attack of Meniere's disease is preceded by full...
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Generally, the aery divides into an anterior division and a posterior division, with the posterior division giving rise to the superior gluteal, iliolumbar, and lateral sacral aeries. The rest usually arise from the anterior division. umbilical aery superior vesical aery obturator aery vaginal aery inferior vesical aer...
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Ans. (d) Grave's ophthalmopathyRef: Parson's, 22/e, p. 487Thyroid eye disease produce typical Fusiform enlargement of extraocular muscles and spares the tendon.
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Ans. Exudates seen in basal cistern
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Ans. is 'c' i.e., Stapes ArchSkeletal elementMuscle archNerve of archIMaxilla, zygomatic bone, part of temporal and vomer, sphenoid, mandible,Malleus, incusMylohyoidMastication musclesAnterior belly of digastricsTensor veli palatineTensor tympaniMandibular division of trigeminalIIStapesStyloid processStylohyoid ligamen...
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The coronary sinus receives blood mainly from the small, middle, great and oblique cardiac veins. It also receives blood from the left marginal vein and the left posterior ventricular vein. It drains into the right atrium. The anterior cardiac veins do not drain into the coronary sinus but drain directly into the right...
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Ans. is 'b' i.e. coarctation of Aorta. Cold extremities, high B.P. in upper extremity with marked diminution of pulsations and B.P. in lower extremity is characteristic of Coarctation of Aorta.More facts about Coarctation of AortaMost patients are asymptomatic.Symptomatic patients usually present with foilwing features...
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Endoscopy is useful for evaluation and treatment of some forms of gastrointestinal obstruction. An impoant exception is a small-bowel obstruction due to surgical adhesions, which is generally not diagnosed or treated endoscopically. Oesophagal, gastroduodenal, and colonic obstruction or pseudo-obstruction can all be di...
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Satyanarayan -562 Leukotrienes are implicated in asthma, inflammatory reactions, hypersensitivity and heart attacks. Leukotrienes cause contraction of smooth muscles, bronchoconstriction, vasoconstriction, adhesion of white blood cells and release of lysosomal enzymes. Lipoxins are involved in vasoactive, and immunoreg...
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Ref-KDT 6/e p101 Neostigmine and pyridostigmine are reversible chlolinesterase inhibitors that can cause cholinergic adverse effects like diarrhea and increase secretions
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image shows red man syndrome which is a side effect of vancomycin usage which increases histamines and causes flushing of the skin Vancomycin: Red Man Syndrome * Constellation of symptoms : Pruritus, flushing, erythroderma common : Hypotension uncommon * Due to nonspecific histamine release that is rate related (rare r...
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Answer is B (CK-MB) CK-MB is the Cardiac Biomarker of Choice for diagnosis of Re-infarction 8 days after the initial ischemic event. The CK-MB level will increase approximately 4-8 hours after a myocardial infarction and return to normal after 72 hours (3 days). This makes it useful for the detection of re-infarction i...
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Referred pain in ovarian pathology -        T10-T11 area, which is a periumbilical area, due to sensory fibers which travel along with sympathetic fibers to aortic plexus. -        Along cutaneous distribution of obturator nerve on the inner side of the thigh.
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Answer is C (Altered mental status) : `Early signs of elevated ICP include drowsiness and a diminished level of consciousness (altered mental status). Coma and unilateral papillary changes are late signs and require immediate intervention.' -Harrisons
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Ans. is 'c' i.e., Discovery of M. Tuberculosis . Louis pasteur is associated with . Development of live vaccine (first was anthrax) . Development of vaccine for rabies (hydrophobia) . Introduction of technique of sterilization . Disprove the theory of spontaneous generation (abiogenesis) . Established the different gro...
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Ans. D. Muir-Torre syndrome*Muir-Torre syndrome is a rare autosomal dominant disorder of DNA repair.*M-Torre syndrome occurs due to mutation in one of the DNA mismatch repair genes (MSH-2, MLH-1, and more recently MSH-6).*The disorder is characterized by sebaceous gland neoplasms, keratoacanthomas associated with gastr...
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Both UL included 18% of burns according to wallace’s rule of 9.
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Interleukin -1 Also known as leucocyte activating factor (LAF) or B cell activating factor (BAF). Principally secreted by macrophages and monocytes, and epithelial cells. Other sources are B lymphocytes, fibroblasts and endothelial cells. Immunological effects- - Activation of T cells for the production of IL - 2....
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The dead body cools at an average rate of 1.5 degree F per hour in temperate climate and 0.75 degree F in a tropical climate. According to Simpson, the cooling of the body is the only reliable indicator of the lapse of time during the first 18 hours after death. Factors controlling the cooling rate are: Condition of th...
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Ans. is ai.e. B/L chocolate cyst of ovary "The ovary is the commonest site and is involved in 30-40% of cases. The lesion is nearly always bilateral. It sometimes appears as multiple burnt match head spots on the surface of the ovary and sometimes as the typical tarry cysts in a disorganised organ surrounded by dense a...
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Ans. (a) Meningitis Strains of Hemophilus which lacks polysaccharide capsule are referred as Non-typable Strains Non-typable H. influenza is the commonest bacterial cause of exacerbations of COPD. They also cause community acquired pneumonia, otitis media (3rd most common cause after pneumococci, and Moraxella catarrha...
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Ans. Megalocornea
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The petrous pa of the temporal bone is pyramid-shaped and is wedged in at the base of the skull between the sphenoid and occipital bones. Directed medially, forward, and a little upward, it presents a base, an apex, three surfaces, and three angles, and houses in its interior, the components of the inner ear . A total ...
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White piedra is caused by Trichosporon beigelli
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Ans. (b) Breast cancer(Ref Internet source)Bloom and Richardson grading for cancer breast is based on* Tubules formation* Nuclear pleomorphisms* Mitotic counts
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Ans. is 'b' i.e., Peptic ulcer Contraindications of Aspirin Peptic ulcer Prostaglandin has cytoprotective function for gastric mucosa by inhibiting acid secretion and promoting secretion of mucus. Aspirin inhibits synthesis of cytoprotective PG -3 bleeding & perforation may occur. Children with chicken pox & influenza ...
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Ans. is 'b' i.e., Lower 1/3 leg and ankle o Venous ulcers usually lie just proximal to the medial or lateral malleolus.o Venous ulcers are accompanied by lipodermatosclerosis and hemosiderosis (if these are not present then the ulcer is probably not of venous origin).
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Ans. B i.e. Urine FSH Physiology Best predictor of ovulation: Pre-ovulatory rise in LH In normal menstrual cycle, progesterone is secreted by: Corpus luteum Inhibin is secreted by: Graffian follicle LH precedes ovulation by: 24 hours (Ovulation coincides with LH surge) Ovulatory period: Corresponds to 14 days before ne...
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Finally, although orthodontic treatment can be carried out during pregnancy,  there are risks involved. Gingival hyperplasia is likely to be a problem, and the hormonal  variations in pregnancy sometimes can lead to surprising results from otherwise predictable  treatment procedures. Because of bone turnover issues dur...
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Neural tube - upper pa: Brain CNS neural plate lower pa: Spinal cord ectoderm Neural crest - ganglia of PNS ARCH. NERVE MUSCLES SKELETON I. Main: CNV (III)Additional: chorda Tympani: (CNVII) Muscles of mastication (temporal, masseter & the pterygoids) ant. Belly of digastric, tensor palatini, tensor tympani. Premaxilla...
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Ans:A i.e. Phosphofructokinase.Rate-Limiting Enzymes Rate-limiting enzyme of Glycolysis :Phosphofructokinase-1 (PFK-1)Rate-limiting enzyme of Gluconeogenesis :Fructose-1,6,biphosphataseRate-limiting enzyme of TCA cycle :Isocitrate dehydrogenaseRate-limiting enzyme of Glycogen Synthesis :Glycogen synthaseRate-limiting e...
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Presence of haematuria with SNHL with anterior lenticonus as shown in the slit lamp suggests the diagnosis of Alpo's syndrome. Alpo's syndrome is and X linked disorder characterized by defect in alpha 5 chain of type IV collagen. Electron microscopy reveals thinning of basement membrane (<150nm) as the earliest feature...
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Ref: Basic & Clinical Pharmacology Katzung 12th ed. p.8J8Explanation:Tetracycline inhibits bacterial protein synthesis by- binding to 30S ribosomal subunit. The remaining drugs are matched correctly with their mechanism of action.
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