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Ans. is `c' i.e. Parvovirus
openlifescienceai/medmcqa
Media which are used for the cultivation of Mycobacterium tuberculosis are LJ media which is most common media used in which growth is seen in 6 to 8 weeks and the colonies are Rough, Buff and tough. The other media used car door fitting media Petragnini media, Saula media, Dubois media or Middlebrook's media. Note-Ext...
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Ans. is d, i.e. Umbilical cordRef. Williams Obs. 22/e, p 68, 69; 23/e, p 61, 62; 23/e, p 61, 62Here are few named structures frequently asked and the organ/structure where it is found.Named structureSeen in* Nitabuch's layerIt is the zone of fibroid degeneration where trophoblast and decidua meet. Seen in basal plate o...
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Aspiration of sperms from testes is done in Testicular sperm aspiration(TESA). In this technique, an aspiration needle is inseed percutaneously to the testis parenchyma to aspirate fluid or small pieces of seminiferous tubules to obtain sperm. Ref: Feility Cryopreservation By Ri-Cheng Chian, Page 52-3; Feility Preserva...
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Ans. (a) CaExocytosis is a calcium dependent process where in the cellular contents are moved out of the cell in the form of vesicles (Cell Vomiting)
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Duration of cardiac cycle (at hea rate of 75/min) is 0.80sec. Out of which duration of systole is 0.27sec and diastole is 0.53sec.
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Because the number of growing follicles is correlated to the size of the primordial follicle pool size, a marker such as antimullerian hormone (AMH) or mullerian-inhibiting substance that reflects all follicles that have made the transition from the primordial follicle pool to the growing pool has been proposed to be a...
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Ans. is 'd' i.e., Disorder of phagocytosis Jobs syndrome is defect in phagocytic function. It is characterized by cold staphylococcal abscess, atopic eczema, otitis media; serum immunoglobulins are normal except IgE that is elevated
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The clavipectoral fascia is a thick sheet of connective tissue that connects the clavicle to the floor of the axilla. It encloses the subclavius and pectoralis minor muscles and spans the gap between them. Impoant structures that pass between the subclavius and pectoralis minor muscles include,Cephalic veinThoraco-acro...
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A i.e. Diazepam; B i.e. Scopolamine; C i.e. Morphine
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Aortic coarctation is common, accounting for 6% of all cases of congenital heart disease. Coarctation usually occurs in the thoracic portion of the descending aorta, distal to the takeoff of the left subclavian artery at the site of the ductus arteriosus. The incidence of a bicuspid aortic valve in association with coa...
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Cysticercus cellulosae is the larval form of Taenia solium. It is found in the tissues of the intermediate host, pig. However, it can also be found in human tissues in cysticercosis. Cysticercosis is usually acquired by eating food or drinking water contaminated by tapeworm eggs from humanfeces or by autoinfection.
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Ans is 'b' ie Ascending infection through biliary tract "Along with cryptogenic infections, infections from the biliary tree are presently the most common identifiable cause of hepatic abscess. Biliary obstruction results in bile stasis, with the potential for subsequent bacterial colonization, infection and ascension ...
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The reading of the genetic code during the process of protein synthesis does not involve any overlap of codons. Thus, the genetic code is nonoverlapping. Features of the Genetic Code: Degenerate Unambiguous Nonoverlapping Not punctuated Universal Ref: Weil P. (2011). Chapter 37. Protein Synthesis & the Genetic Code. In...
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The herpesvirus has double-stranded linear DNA, which is unusual because it has terminal and internal repeated sequences. The DNA of some of its members (e.g., herpes simplex viruses) can undergo genetic rearrangement, which results in four different genomic isomers. In an isomer, there is the same molecular formula bu...
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Treatment of multiple carboxylase or biotinidase deficiency is biotin.Oral dose is 10-40 mg/kg/day Reference:Essential pediatrics-Ghai,8th edition,page no:650
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Niemann-Pick diseases are genetic diseases which are classified in a subgroup of LSDs called sphingolipidoses or lipid storage disorders in which harmful quantities of fatty substances, or lipids, accumulate in the spleen, liver, lungs, bone marrow, and brain.In the classic infantile type A variant, a missense mutation...
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The orbit appears as quadrangular pyramid in shape, i.e. Resembles a four-sided pyramid, which has an apex, base, four walls - roof, floor, medial and lateral walls.
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Indications of tracheostomy: 1- Upper respiratory tract obstruction; Laryngeal, supralaryngeal ,and tracheal causes.( Causes of stridor ) 2- Lower respiratory tract obstruction: (Secretory obstruction, Wet lung syndrome). ref: hazarika 4th ed
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Toll-like receptors * TLRs in humans recognize PAMPS (pathogen associated molecular pattern) and are usually expressed on APCs. * Interaction between TLRs on APCs and PAMPS on pathogens activation of APCs and presentation of pathogen-derived antigen to T-cells forms a link between the innate and adaptive immune systems...
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Ans. D i.e. Clinical examination, Mammogram & FNAC
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Fluid and electrolyte replacement is central to the treatment of diarrheal illnesses. Indications for therapy include high fever, bloody diarrhea, severe diarrhea, persistence for >1 week, and worsening of symptoms. A 5- to 7-day course of erythromycin (250 mg orally four times daily or--for children--30-50 mg/kg per d...
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Nodular lesions of diabetic glomerulosclerosis are also called as Kimmelstiel- Wilson (KW) lesions or intercapillary glomerulosclerosis. These lesions are specific for type 1 diabetes (juvenile onset diabetes) or islet cell antibody-positive diabetes mellitus. The pathologic changes consist of one or more nodules in a ...
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Ans. is 'c' i.e., Neonatal jaundice Phenobarbitone* Phenobarbitone is a long acting barbiturate.* Barbiturates induce several hepatic microsomal enzymes and increase the rate of metabolism of other drugs.* This property of phenobarbitone can be used as an adjuvant in treatment of neonatal jaundice.* In cases of unconju...
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Digoxin is eliminated mainly via excretion through kidney whereas digitoxin is metabolized by the liver. The dose of digoxin, therefore, does not require an adjustment in hepatic failure whereas it has to be reduced in renal failure. The arrhythmogenic dose of digitalis is reduced in MI. It should be used after MI only...
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(Refer: AK Khurana Comprehensive Ophthalmology, 6th edition, pg no. 381) Fasanella-Servat operation: It is performed in cases having mild ptosis (1.5-2mm) and good levator function. In it, upper lid is eveed and the upper tarsal border along with its attached Muller's muscle and conjunctiva are resected. Fasanella Serv...
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RBCs shape and size malaria: P. vivex - Enlarged, Round and Bizarre form P. falciparum - Normal in size P. malariae - Normal in size P. ovale - Enlarged, Oval and Fimbriated margin Relapse: Seen in P. vivax and P. ovale Recrudescence: Seen in P. falciparum and P. malariae infections Definitive host: Female Anopheles mo...
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Ans. is 'a' i.e., Gene expe GeneXpe MTB/RIF The Xpe MTB/RIF detects DNA sequences specific for Mycobacterium tuberculosis and rifampicin resistance by polymerase chain reaction. It is based on the Cepheid GeneXpe system, a platform for rapid and simple-to-use nucleic acid amplification tests (NAAT). The Xpe MTB/RIF pur...
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Ans. is 'c' i.e., Mid - arm circumference
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Ans. is b, i.e. Anthropoid pelvisRef. Dutta Obs. 9/e, p 325, Table 24.1, 8/e, p 403, Table 24.2As discussed in the text in Table 7.2 face-to-pubis delivery is common in anthropoid pelvis.
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Ehlers-Danlos syndromes are characterized by defects in collagen (i.e., connective tissues).
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Ref: Grays Anatomy, 40th ed., Dhingra PL. s ENTExplanation:BOUNDARIESThe laryngopharynx is situated behind the entire length of the larynx (known clinically as the hypopharynx) and extends from the superior border of the epiglottis, w'here it is delineated from the oropharynx by the lateral glossoepiglottic folds, to t...
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Fluoxetine is a selective serotonin Reuptake Inhibitor (SSRI) and SSRIs have shown the greatest efficiency in PMS treatment. Premenstrual syndrome (PMS), also called Premenstrual Tension (PMT), is a symptom complex, recognised primarily by cyclic changes, associated with ovulatory cycles. It occurs 7 to 14 days prior t...
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Patient suffers from Urinary tract infection, Dapagliflozin is the causative drug here. Dapagliflozin It is a sodium-glucose co-transpoer-2 inhibitor Improve glycemic control by inhibiting glucose Inhibit glucose reabsorption in the proximal tubule of the nephron | result in Glucosuria | result in urinary tract infecti...
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Ans. is 'c' i.e., Distal fragment In distal third shaft fracture or supracondylar femur fracture, the distal fragment is tilted backward due to strong gastrocnemius pull. This posteriorly tilted distal fragment can cause popliteal aery injury.
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D i.e. Transverse perenii superficialis- Superficial perineal muscles include bulbospongiosus, ischiocavernosus & superficial transverse perinei- Perineal body is formed by superficial & deep transverse perini, levator ani, bulbospongiosus, sphincter urethrae & external anal sphincter.Superficial transverse perinii mus...
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RIFLED GUN RIFLING: Interior of bore has spiral grooves which run parallel to each other, but twisted spirally from breech to muzzle end. These grooves are called 'rifling' Impas Spinning motion to the bullet Greater power of penetration Straight trajectory Increases accuracy & range Paradox gun: A smooth bore gun with...
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Rosai Dorfman disease: Massive cervical lymphadenopathy, usually bilateral and painless, is the most common manifestation. It is generally a benign disorder in spite of its propensity to form large masses and to disseminate to both nodal and extranodal sites.
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Ans. A i.e. Vitamin E Vitamin E is the collective name for a set of eight related tocoplzerols and tocotrienols, which are fat-soluble vitamins with antioxidant propeies.
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Ans. is 'd' i.e., Platelete count o Bleeding from mucosal surface suggests thrombocytopenia or defect in platelet function. o First do platelet count, if there is thrombocytopenia, fuher investigation will be required.
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parks textbook of peventive and social medicine 23rd edition. *relevant aicles for the right of child are : aicle 24 prohibits employment of children below the age of 14 in factories aicle 39 prrevents abuse of children of tender age aicle 45 provides for free and compulsory education for all children until they comple...
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LDL receptors  Familial hypercholesterolemia (type IIa) is due to deficiency of functional LDL receptors as a result of different types of mutations.
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Ref. Guyton. 13th edition. Page. 435 Countercurrent multiplication in the kidneys is the process of using energy to generate an osmotic gradient that enables you to reabsorb water from the tubular fluid and produce concentrated urine.   The three segments of the loops of Henle have different characteristics that enable...
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Answer is B (Presentation is Unilateral): The presentation in Polycystic disease of kidney is characteristically bilateral - The bilateral enlargement can hardly be mistaken on routine examination - Bailey - USG and CT show multiple cysts in both kidneys - Bailey The disease may present at any age but the most common a...
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Ref:Textbook of forensic medicine and toxicology (V.V.Pillay) 17th edition, page no.367 The MTP Act of 1971 was passed to liberalise aboions in india , on the basis of clearly specified guidelines. This liberalization was decided upon with idea of saving the lives of millions of women, who would other wise reso to crim...
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Prions disease is produced due to miss folded proteins Most common type of prions disease is: creutzfeldt-jakob disease Ref:Guyton and Hall textbook of medical physiology 12th edition,page number:10,11,12
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Barrett's esophagus Is metaplastic change of distal esophageal mucosa from normal squamous epithelium to columnar epithelium, in response to chronic gastro-esophageal reflux. The junction between squamous esophageal mucosa and gastric mucosa moves proximally Three types of columnar epithelium have been described in B...
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Helium ion (alpha rays) has maximum ionisation potential Gamma rays have maximum penetration power.
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A i.e. It has lower threshold than rest of axonAxon hillock is the initial segment of neuron, nerve impulses begin in this initial segment of axon because it has lowest threshold potential.QAxon hillock:- This is a thickened area of cell body from which originates the long fibrous axon.AP is generated in this segment b...
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Answer is C (Injury to coical bridging veins): Subdural hemorrhage is caused by the rupture of bridging veins that connect the brain and the dural sinuses i.e. coical bridging veins. Memo: Most common cause of extradural hemorrhage is Rupture of middle meningeal aery.
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Ans. is 'b' Autistic Disorder Symptoms of the child and H/o Birth Asphyxia strongly suggests the diagnosis of Autistic Disorder.Birth Asphyxia is a common came of this disorderAutistic Disorder1. Impairment in social and interpersonal interactions.2. Impairment in language and nonverbal communication3. Mental retardati...
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Ans. Vasculotoxic
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It includes increase in pulmonary ventilation, increases in RBC count and hemoglobin content, increase in 2,3-DPG.(Ref. Textbook of physiology N Geetha 2nd edition page no.265)
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Patchy loss, exclamation mark hair, autoimmune - Alopecia areata Alopecia areata is the commonest cause of patchy alopecia. Loss of Hair following a stress, infection etc - Telogen effluvium Loss of hair after Chemotherapy - Anagen effluvium Frontotemporal Recession - Androgenetic alopecia
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Clinical features in an HIV infected infant is:Recurrent GI infection and oral thrush is commonly foundClinical features in older children:Growth failureFeverDiarrheaSecondary infection(Refer: OP Ghai's Textbook of Pediatrics, 8th edition, pg no. 202)
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Ans/. Weight
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Close to 90% of episodes of otitis media with effusion (glue ear) resolve spontaneously after an acute otitis media episode is diagnosed. The American Academy of Pediatrics 2004 consensus guideline recommends watchful waiting without immediate use of antibiotics for children with uncomplicated otitis media with effusio...
openlifescienceai/medmcqa
Ref. Rook's Textbook of Dermatology, Pg 35   Histology of skin Basal layer: Mitotically active, produces other keratinocytes Contains low molecular weight keratin Separated from dermis by continuous basal membrane; keratinocytes are attached to this membrane by hemidesmosomes Also contains melanocytes   Squamous ...
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HHV 4 or Epstein Barr virus can cause nasopharyngeal carcinoma.
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(Acute epiglottitis): (309-Dhingra 5th; 599-P-Hazarika 3rd/edition)ACUTE EPIGLOTTITIS(Syn - Acute supraglottic laryngitis)* Caused by Hemophilus influenza type BClinical FeaturesSymptomsSignsGeneral - usually starts as URTISigns* High grade fever* General - fever, toxic appearance and flushed skin, lethargic* Dribbling...
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Ref: Goodman eft Gillman, The pharmacological basis of therapeutics. 12th edition, Pp-1294.1298, 1300Explanation:In Paget's disease. Calcitonin is administered by subcutaneous route and intranasal spray is not preferred because of the limited bioavailabilitv.It reduces serum calcium and phosphate levels in paget's dise...
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-Sacral agenesis or Caudal regression syndrome is the most specific congenital abnormality in a baby born to a diabetic woman.
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Timing of elective delivery in twin pregnancy Uncomplicated dichorionic: 38 weeks Uncomplicated monochorionic diamniotic: between 34 to 37 weeks Monoamniotic: 32-34 weeks, To be done by LSCS only due to high risk of conjoint twins, cord entanglement No role of prophylactic tocolytics, progesterones or prophylactic cerv...
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Carney triad (CT) is characterized by the coexistence of three types of neoplasms, mainly in young women, including gastric gastrointestinal stromal tumor, pulmonary chondroma, and extra-adrenal paraganglioma. The underlying genetic defect remains elusive. Ref - Davidson 23rd edition pg 545
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Ans. (c) Terminal ileum(Ref: Robbins 9th/pg 375-376)Extrapulmonary TB:MC site is lymph node Q, MC cervical & supraclavicular ("Scrofula") QPleural involvement: Exudative Q Pleural effusion, tuberculous empyema, or obliterative fibrous pleuriticGenitourinary TB: sterile pyuria Q; Preferentially involves fallopian tube Q...
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Runt disease is Graft versus host disease. Runt disease occurs when immunologically competent donor cells are transplanted into immunologically crippled (immunocompromised) hosts and the transferred cells recognize host cells as alloantigens.
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Ans. is 'a' i.e., Lucio leprosy Lucio phenomenon It is found in lucio leprosy with type 2 lepra reaction. It is prevalent in mexico. Characterized by painful tender red patches paicularly on extremities which later on become necrotic and finally develop into brown black eschar. Ulcers are more persistent on legs. Tuber...
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Ans. A:Osteogenesis imperfecta Osteopetrosis is also known as Marble bone disease or Albers-Schonberg disease. Paget's disease is known as Osteitis deformans. Osteogenesis imperfecta is known as Brittle bone disease. Osteoporosis is known as Fragile bone disease.
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Acetohexamide is a first generation sulfonylureas which acts by stimulating insulin release from pancreas. Sulfonylureas block K+ channels in beta cells leading to depolarization, increased calcium entry voltage dependent calcium channels and increased secretion. It also increases insulin sensitivity by increasing the ...
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Blepharitis * Sub-acute or Chronic inflammation of lid margins * Can be bacterial, seborrheic, parasitic * Symptoms: Irritation, itching, lacrimation, gluing of cilia, mild photophobia. * Yellow crusts are seen at the root of cilia which glue them together * Can lead to abnormalities like madarosis, trichiasis and poli...
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The most specific way to make a diagnosis of acute gout is to aspirate the involved joint and to identify negatively birefringent, needle shaped crystals under red-compensated polarized light. The next best way to make a diagnosis of gout is to give oral colchicine hourly until the patient develops significant improvem...
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A i.e. Alters gene expression; B i.e. Genetic code remains intact; C i.e. Role in carcinogenesis and Protective mechanism against cleavage by restriction endonuclease DNA methylation alters the gene expression pattern in cells-for example it may cause X-chromosome inactivation, tumor suppressor gene silencing (in cance...
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<p>In cold agglutinin disease, antibody is usually IgM which reacts with red cells poorly or not at all at 37 degree celsius ,whereas it reacts slowly at lower temperature . Donath - Landsteiner antibody is involved in paroxysmal cold hemoglobinuria. Warm antibody immunohemolytic anemiaa are caused by UgH ir rarely ItS...
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B i.e. pain on passive extension of finger
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Chlolinometic drug will cause bradycardia as an adverse effect and thus cannot be used for its treatment Ref-KDT 6/e p104
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Kocher's maneuver is used for the reduction of shoulder dislocation. These are methods of Closed hip reduction: Allis maneuver Stimson maneuver Lefkowitz maneuver East Baltimore lift maneuver Bigelow maneuver
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This is a case of brachial neuritis following an injection of tetanus toxoid. Here there is dysfunction of the nerves supplying the arm or shoulder without involvement of the rest of the nervous system. The sensory loss is less prominent than the weakness. There may also be bilateral involvement of muscles with wasting...
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Randomization is a statistical procedure by which the paicipants are allocated into groups usually called 'control' and 'study', to receive or not to receive an experimental, preventive or therapeutic procedure manoeuvre or intervention. Ref: 25th edition, Park's Textbook of Preventive and Social Medicine, Page no. 90
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The Transplantation of Human Organs Act 1994, amended in 2011, and 2012 Chapter VI and VII deals with the trial and punishment of offences under this act. Under this act, doctors involved will be punished for a period of 2-5yrs. Ref: FORENSIC MEDICINE AND TOXICOLOGY Dr. PC IGNATIUS PAGE NO: 389
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Glanzmann's thrombasthenia - It is an autosomal recessive disorder due to deficiency/dysfunction of glycoprotein Ilb-IIla (Gp Ilb/IIIa). Thus there is defective platelet aggregation. Platelet aggregation is normal to ristocetin(ln constant to Bernard Soulier syndrome) but no aggregation occurs in response to standard a...
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"Cystoid macular edema is a common cause of visual loss in patients with uveitis and may be observed in the setting of severe anterior or intermediate uveitis. Long-standing or recurrent macular edema can cause permanent loss of vision due to cystoid degeneration". - Lange Ophthalmology
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In humans carnitine is synthesized from protein-derived trimethyllysine in liver, brain and kidney.Muscles take up carnitine from the blood in an exchange-diffusion process with endogenous deoxycarnitine, the immediate precursor of carnitine.Besides catalysing the transpo of long-chain acyl groups in mitochondria, carn...
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Ans. is 'a' i.e., Staph Aureus o MC organism is staph aureus >> str. viridans >> pneumococcus.
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Ans. is 'a' i.e., Plasmin Streptokinaseo Fibrinolytic drugo Obtained from group C streptococcio Streptokinase is inactive as such. It combines with circulating plasminogen molecules to form an activator complex, which then causes limited proteolysis of other plasminogen molecules to generate active enzyme plasmin.
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Ans. is 'd' i.e., Varenicline o Varenicilline is a direct acting nicotine agonist with selective action on a4 b2 isoform of Nm receptors. It is an antismoking drug.
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Ans. (c) VIII(Ref: Wintrobe's 13th/pg 1389)vWF is required for normal platelet adhesion, and also acts as a carrier of factor VIII in the plasma
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HCG has the same stimulatory effect as LH on the corpus luteum. Administration of HCG would cause the corpus luteum to continue to secrete estrogen and progesterone, preventing degradation of the endometrium and the onset of menstruation
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(Aldosterone): Ref: 258-H (280- H178th) (358- Ganong 23rd)Aldosterone is secreted by the zona glomerulasa cells of the adrenal cortex in response to high renin and angiotensin II or hyperkalemia (258-H)Plasma K+ level needs increase only 1 mEq/L stimulate aldosterone secretion
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Answer is None "A skin specimen containing Paget cells secures the diagnosis and can be obtained by nipple scrape cytology or biopsy."
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Ans. is 'b' ie pressure abrasion (Ref: Parikh; 6/e, p4.3).An abrasion is a superficial injury involving only the superficial layers of the skin (epidermis only), caused by friction and / or pressure between the skin and some rough object or surface. It bleeds very slightly, heals rapidly in a few days and leaves no sca...
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Glucagon is produced by the alpha cells of the pancreass. The same gene for glucagon also code for glucogagon like peptide - GLP 1 and GLP 2. GLP 1 1. Stimulates insulin secretion 2. Augments insulin releasing effects of glucose This effect is responsible for enteroinsular axis ALSO NOTE: GLP 1 analog: Stimulates insul...
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Erythema multiforme is a skin reaction that can be triggered by an infection or some medicines. It's usually mild and goes away in a few weeks. There's also a rare, severe form that can affect the mouth, genitals and eyes and can be life-threatening. This is known as erythema multiforme major .Additional symptoms of er...
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- The image shows mass on top of kidney, indicative of adrenal pathology. Since hypeension is present with hypokalemia, increased aldosterone from adrenal adenoma is diagnostic of Conn syndrome. - Pheochromocytoma has hypeension but hypokalemia is not seen. - Liddle syndrome is autosomal dominant disorder with over act...
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ICD-10 (International Classification of Diseases, 10th revision on January 1, 1993). ICD does uniform classification of diseases which can be used throughout the world to make accurate comparisons of morbidity and mortality data for decision making in prevention, facilitation and management of health care system. ICD-1...
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Causes of Hypehermia Syndromes: Heat Stroke Exeional: Exercise in higher than normal heat and/or humidity Nonexeional: Anticholinergics, including antihistamines; antiparkinsonian drugs; diuretics; phenothiazines Drug-Induced Hypehermia Amphetamines, cocaine, phencyclidine (PCP), methylenedioxymethamphetamine (MDMA; "e...
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This is a case of pulled elbow. Treatment is simple. The child's attention is diverted, the elbow is quickly supinated and then slightly flexed.
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Ans. is 'b' i.e., Hyponatremia Causes of status epilepticus in children o Idiopathic o Drug intoxication o Congenital/Developmental neurological abnormalities o Hypoglycemia o Meningitis, Encephalitis o Hyponatremia o Head trauma o Pyridoxin deficiency
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Prolactin- a hormone secreted by the anterior pituitary gland that promotes the growth of breast tissue and stimulates and sustains milk production in postpaum mammals, and shows luteotropic activity in ceain mammals. Called also lactogenic hormone and mammotropin.Ref: Ganong&;s review of medical physiology;24th editio...
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One of earlier symptoms of ammonia intoxication is haziness of vision and slurring of speech Other clinical features of urea cycle defects:- Increased blood glutamine Decreased BUN (Blood Urea Nitrogen) Cerebral oedema Vomiting Lethargy hyperventilation Note:-Severe ammonia toxicity can lead to coma and eventually deat...
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Olfaction is greater in female then in males Ref: guyton and hall textbook of medical physiology 12 edition page number:645,646,647
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