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135
33d29145-1361-423b-9407-3ee80a60789e
Period of sickness benefit given under ESI Act
41 days
17 days
91 days
101 days
2c
single
null
Social & Preventive Medicine
null
ad1bca5c-d47b-4db6-ba81-8a44243e1d66
The drug which is used for long term maintenance in opioid addiction
Naloxone
Nalorphine
Butarphanol
Methadione
3d
single
Ans. is 'd' i.e., Methadone Maintenance therapy for opioid addiction* Once detoxification phase is over (i.e., withdrawal symptoms have been managed), the patient is maintained on any of the following drugs to prevent relapse by reducing craving and preventing 'kick' or 'euphoria' produced by opioids (morphine or heroi...
Psychiatry
Substance Abuse
9f26336f-ad93-476d-b352-e927ca5b592c
DNA depended RNA synthesis is inhibited by:
Rifampicin
Ethambutol
Colchicine
Chloromycetin
0a
single
Rifampicin
Pharmacology
null
4dc4fca8-fdd8-41ac-b5a2-ed0cc5696b1a
Which of the following statements regarding the flow of lymph from lower limb is true?
|ed with change from supine to standing position
|ed in increased capillary permeability
|ed in deep vein valve incompetence
|ed by massage of foot
3d
multi
Normally. the fluid in lymph is massaged by muscle contractions of the organs and contraction of aerioles and venules, with which they are often associated which increases the flow through lymph vessels lacking valves and smooth muscle Thus by massaging foot lymph flow can be increased Ref: Ganong's Review of Medical P...
Physiology
Cardiovascular system
2b5946ed-dbdc-47b7-a409-f9f279b13e23
Contraindication of liver transplant?
Acute fulminant hepatic failure
Metabolic Disease
Metastasis
Primary liver malignancy
2c
single
Ans. (c) MetastasisRef: Sabiston 19th edition, Page 657* Contraindications for Liver transplant:# Metastatic liver disease# Poor cardio-pulmonary reserve# Systemic infections (HIV is not a contraindication now)# Porto pulmonary hypertension with pulmonary artery pressure >50mmHg # Hepatopulmonary syndrome when PaO2 doe...
Surgery
Transplantation
306616e8-402c-420a-a4ef-d442e779c972
Meniscal injury occurs during:
Rotation
Extension
Rotation and Flexion
Flexion
2c
single
Ref: Apley's System of Orthopaedics and Fractures, 8th ed.Explanation:Mechanism of injury to MeniscusDamage to the meniscus is due to rotational forces directed to a flexed knee (as may occur w-ith twisting sports) is the usual underlying mechanism of injury.A valgus force applied to a Hexed knee with the foot planted ...
Orthopaedics
Knee Ligament Injuries
e297ae54-65c4-4d73-9330-b27a20545aaa
Zero order kinetics is independent of ?
Plasma concentration
Clearance
Volume of distribution
Half life
0a
single
Ans. is 'a' i.e., Plasma concentration o Rate of elimination in zero order kinetics is independent of plasma concentration (see above explanation).
Pharmacology
null
610f2d96-bf48-43c7-8e96-f8fe476d9609
Spinal shock is characterised by -a) Spasticityb) Wastingc) Sensory lossd) urinary retentione) Areflexia
abd
acd
bde
cde
3d
single
null
Medicine
null
803af4d5-8dbc-4c8f-b14b-21af13053c77
Which of the following is true regarding non-competitive enzyme inhibition?
Vmax increases
Vmax decreases
Km increases
Km decreases
1b
multi
In case of non-competitive enzyme inhibition Vmax decreases and Km remains the same.
Biochemistry
null
fbb17b41-708d-493b-8ee2-4403261f01ab
Occipitofrontal is muscle is present in which layer of scalp:
Aponeurotic layer
Subaponeurotic layer
Dense connective tissue layer
Loose connective tissue layer
0a
single
Ans. A. Aponeurotic layerThe term scalp is applied to the soft tissues covering the vault of skull. It extends anteriorly up to the eyebrows (superciliary arches), posteriorly up to the superior nuchal lines, and laterally on each side up to superior temporal line. The scalp consists of five layers. From superficial to...
Anatomy
Head & Neck
7304abd1-d146-4143-ae01-8d102ae7b5fb
Gleason's staging is used in:
Ca prostate
Ca bladder
Ca pancreas
Ca colon
0a
single
Ans: A (Ca prostate) Ref: Bailey & Love s Short Practice of Surgery, 25th Edition & Internet SourcesExplanation:The Gleason Grading SystemIt is used to help evaluate the prognosis of men with prostate cancer.It also predicts prognosis and helps guide therapy.Scoring based upon its microscopic appearance on histopatholo...
Surgery
Prostate Cancer
5217c6d9-9a1b-4a77-b32f-64f242ad76b8
The distance between tympanic membrane and medial wall of middle ear at the level of centre is:
3 mm
4 mm
6 mm
2 mm
3d
multi
(d) 2mm(Ref. BD Chaurasia, Human Anatomy 6th ed., Vol 3, page 277)Part of the middle ear cavityDistance from lateral to medial wallEpitympanum6mm (widest)Mesotympanum (centre)2mm (narrowest)Hypotympanum4mm
ENT
Ear
72e6f5b0-4ba3-4e63-b874-bc37fcf15b72
Dystrophic calcification occur in all except -(
Rheumatic hea disease
Lymph node
Normal kidney
Aneurysm
2c
multi
Ans. is 'c' i.e., Normal kidney
Pathology
null
bc50d685-8468-4b36-86a5-dbf5f45a3b65
A patient with peptic ulcer disease undergone billroth 2 gastrectomy. Later the patient presented with postprandial pain. On endoscopy oedematous and inflamed gastric mucosa has been found. What is the preferred diagnosis
Alkaline gastritis
Dumping syndrome
Gastroparesis
None of the above
0a
multi
Reflex of duodenal juices into the stomach after billroth surgery e will cause inflamed gastric mucosa. Treatment of choice is roux en y gastrojejunostomy.
Surgery
null
e3bbb17f-e7e4-4b6c-ac2a-6ae6f10deb50
In muscle cells, resting membrane potential is equal to the isoelectric potential of
Na+
Cl-
K+
Mg++
2c
single
The isoelectric potential of Cl- is -70mV and of K+ is -90mV. According to ‘Ganong’ and ‘Principles of Medical Physiology’, the actual measured RMP of a nerve fibre is -70mV rather than the calculated value of -90mV. So in nerve fibres, the RMP is equal to or closer to the isoelectric potential of Cl-. Whereas in musc...
Physiology
null
0436a661-0888-4f34-855d-d105eb49cd49
Subcutaneous vaccine is -
BCG
Polio
DPT
Measles
3d
single
Ans. is 'd' i.e. measles Mode of administration of vaccines* BCG* intradermal* OPV* oral* DPT* Intramuscular* Measles* subcutaneously
Social & Preventive Medicine
Principles of Immunization and Vaccination
89b8f81f-87a6-4e2a-b2cd-5a595b2caa26
True about shigella dysentriae except -
It invades colonic mucosa
It can cause HUS
Produces verocytotoxin
Produces mildest form of dysentry
3d
multi
Ans. is 'd' i.e., Produces mildest form of dysentry * Mildest form of dysentry is caused by Sh. Sonnei.
Microbiology
null
5f099f2b-0b6c-4995-9181-70369c47206b
A female presented with a severe headache of sudden onset. On CT scan a diagnosis of subarachnoid hemorrhage is made. The most common cause of subarachnoid hemorrhage is :
Middle meningeal artery
Berry aneurysm rupture
Basilar artery
Subdural venous sinuses
1b
single
Ans. is 'b' ie. Berry Aneurysm (Ref. : Harrison, 17/e pl726 (16/e, p 2387, 15/e, p 238))" Excluding head trauma the most common cause of SAH is rupture of a saccular aneurysma (Berry aneurysm or congenital aneurysm). "Berry aneurysms - also k/a as congenital aneurysm although they are not present at birth. There is how...
Unknown
null
8eb81a4a-3ff4-46da-b56f-21711a6c6ebd
Pulsus paradoxus is seen in all except :
IPPV
COPD
Cardiac Temponade
Constrictive pericarditis
0a
multi
Answer is A (IPPV) Pulsus paradoxus is not a feature of IPPV. Pulsus paradoxus may be seen in association with cardiac tamponade, constrictive pericarditis (infrequent) and COPD. Causes of Pulsus Paradoxus 1. Clinical Disease States Cardiac Tamponade (common) Constrictive Pericarditis (Infrequent) Superior vena cava sy...
Medicine
null
2e8dd29e-d95a-4d37-a864-e4a59f466924
The following are characteristic of autism except ___________
Onset after 6 years of age
Repetitive behaviour
Delayed language development
Severe deficit in social interaction
0a
multi
Autistic disorder:- Pervasive developmental disorders. Also called autistic spectrum disorders, cluster of syndromes that share marked abnormalities in the development of social and communicative skills. Symptoms: Qualitative impairment in social interaction as manifested by two of the following- impairment in use of m...
Pediatrics
Growth and development
6185a27a-a703-48e7-b947-f36509811a86
Which among the following is not an RNA virus?
Hepatits A
Hepatitis B
Hepatitis C
Hepatitis D
1b
single
Ans: b (hepatitis B) Ref:Ananthanarayan, 7 p. 547Among the hepatitis virus only DNA virus is hepatitis B virus (Hepadna virus). Just go through theFeatureHAVHBVHCVHDVHEVAgentSSRNA icosahedral,capsid unenvelopedDSRNAComplex structure envelopedSSRNA envelopedSS defective virus envelopedSSRNA unenvelopedClassificationPico...
Microbiology
Virology
d6426c2a-1da1-4523-906a-741cfeb77d13
An old man enters the hospital with myocardial infarction and a severe ventricular arrhythmia. The antiarrhythmic drug chosen has a narrow therapeutic window. The minimum toxic plasma concentration is 1.5 times the minimum therapeutic plasma concentration. The half life is 6 hrs. It is essential to maintain the plasma ...
Once a day
Twice a day
Four times a day
Constant intravenous infusion
3d
multi
null
Pharmacology
null
5e745d6b-e03c-43e0-a20c-46c7d5a7e313
The most common indication for tracheostomy is:
Laryngeal diphtheria
Foreign body aspiration
Carcinoma
Asthma
1b
single
Historically, the main indication for a tracheostomy was to bypass upper airway obstruction caused by a foreign body or infection, paicularly diphtheria. Nowadays upper airway obstruction is the least common indicator for tracheostomy. Almost two thirds of tracheostomies are currently performed on intubated intensive c...
ENT
null
a94b5a12-bac7-45a8-b9a2-db8ced7eebd5
Absolute contraindication of OCP's is:
Breast cancer
Mentally ill
Migraine
Fibroid
0a
multi
null
Gynaecology & Obstetrics
null
e5e017a0-2f53-4392-9722-956936faed9a
Epicritic perception of pain occurs at the level of
Thalamus
Area 3, 1, 2
Areas 5, 7
Pulvinar
1b
single
null
Physiology
null
ef1bbbc6-c2a7-403c-96b6-f42d6d44027c
A 35-year-old man comes to the physician because of a lump in his neck. Examination shows a thyroid nodule, Laboratory studies show serum calcitonin is elevated, and serum calcium is normal Despite high serum calcitonin levels, which of the following mechanisms best explains the normal calcium levels in this patient...
Concurrent parathyroid adenoma
Concurrent parathyroid hyperplasia
High levels of calcitonin down reQulates its receptor
Increase in PTH in response to hypocalcemia
2c
single
null
Medicine
null
0d5dede3-bc48-4bfb-bc7b-01e5cbdf29e1
Aflatoxin is produced by the fungus?
Aspergillus flavus
Aspergillus fumigatus
Aspergillus niger
Penicillium marneffei
0a
single
Aflatoxin is a mycotoxin that is produced by the fungi Aspergillus flavus and Aspergillus parasiticus. Exposure to aflatoxin can cause hepatic necrosis later progressing to cirrhosis. It also acts as a carcinogen and can produce hepatocellular carcinoma.
Microbiology
Mycology
f0b1a64c-3784-4deb-9b6c-10b0ef6eb573
Ram Prashad is admitted to Guru Teg Bahadur Hospital with respiratory infection for which antibiotic tobramycin is ordered. The clearance and Vd of tobramycin in him are 160 ml/min and 40 L, respectively. If you wish to give Ram Prashad an intravenous loading dose to achieve the therapeutic plasma concentration of 4 mg...
0.1 mg
10 mg
115.2 mg
160 mg
3d
single
Loading dose = Vd x target plasma cone. = 40 L x 4 mg/L = 160 mg Clearance plays no role in the determination of loading dose. It is given to confuse you.
Pharmacology
null
14263e2b-6bb5-4b61-ad08-6c96f024ec8b
Extra cervical rib usually compresses which pa of brachial plexus -
Lateral cord
Upper trunk
Middle trunk
Lower trunk
3d
multi
THORACIC OUTLET SYNDROME Neurological and vascular symptoms and signs in the upper limbs may be produced by compression of the LOWER TRUNK of the brachial plexus (C8 and T1) and subclan vessels between the clavicle and the first rib. The subclan aery and lower brachial trunk pass through a triangle based on the first r...
Orthopaedics
Miscellaneous
6c9ebdc7-8d66-4b68-982a-761223c5de66
The following structure does not pass through flexor retinaculum
Ulnar N
Median N
Flexor digitorum profundus
Flexor digitorum superficialis
0a
single
FLEXOR RETINACULUM Carpel tunnel.Transverse carpal ligament. Strong fibrous band which bridges anterior concavity of carpus and conves it into osseofibrous tunnel called carpal tunnel for the passage of flexor tendons of the digits. Rectangular.Formed due to thickening of deep fascia in front of carpal bones. Attachmen...
Anatomy
Upper limb
43b33cf4-1938-4285-b9a1-6068a19e1bd7
To diagnosis foetal wellbeing of foetus, most reliable method -(UPSC 97)
L:S ratio
HPL levels
Kick test
Ultrasound
3d
single
To get started, sit with your feet up or lie on your side. Count each of your baby'smovements as one kick, and count until you reach 10 kicks or movements. Most of the time it will take less than a half-hour, but it could take as long as two hours. Log your recorded times into a Count the Kicks chart. The lecithin-sphi...
Gynaecology & Obstetrics
Diagnosis in Obstetrics
b69ee41f-6de3-4002-a19f-4f21af1e880f
Drug commonly used against enteric fever are all except-
Amikacin
Ciprofloxacin
Ceftriaxone
Azithromycin
0a
multi
Aminoglycosides are not given for enteric fever
Microbiology
null
19dbb51a-75ee-4e72-b26c-711d85a582f7
Hiatus semilunaris is present in?
Superior meatus
Middle meatus
Inferior meatus
Spheno-ethmoidal recess
1b
single
Middle meatus: Uncinate process is a hook-like structure running in from anterosuperior to the posteroinferior direction in the middle meatus. It&;s postero superior border is sharp and runs parallel to the anterior border of bulla ethmoidalis. This gap between the two is called hiatus semilunaris .it is two-dimensiona...
ENT
Nose and paranasal sinuses
3c6ced6c-0e79-4933-a349-ffc7a598cd5a
After an incised wound, new collagen fibrils are seen along with a thick layer of growing epithelium. The approximate age of the wound is:
4-5 days
About 1 week
12-24 hours
24-72 hours
0a
single
The approximate age of the wound in an incised wound, when new collagen fibrils are seen along with a thick layer of growing epithelium is 4-5 days.
Pathology
null
5288c03d-1e35-419b-8b16-dcd64ae7138c
Shoest skull diameter: March 2013
Biparietal
Mentoveical
Bitemporal
Bimastoid
3d
single
Ans. D i.e. Bimastoid Fetal skull Shoest diameter of fetal skull: Bimastoid (7.5 cm) Largest diameter of fetal skull: Mentoveical (14 cm)
Gynaecology & Obstetrics
null
3fefd03a-5ba5-446e-a433-bdb6057d825f
Regarding yaws, all are true except -
Caused by T. Peenue
Sexually transmitted
Croos active antibodies with syphilis
Drug of choice is penicillin
1b
multi
Yaws is a chronic contagious non veneral disease. Reference; Park&;s Textbook of preventive and social medicine, 24th edition.Pg no. 359
Social & Preventive Medicine
Communicable diseases
d52c957e-e1ae-48cc-8e0d-2f8732fc08ee
Surgery for undescended testis is recommended at what age?
6 months
12 months
24 months
36 months
0a
single
Optimum age for surgery in case of undescended testis is 6 months. The surgical procedure done is called orchidopexy. Earlier intervention (Six months of age) should be considered in order to theoretically prevent the complications of crytorchidism that may be manifested before 1 year of age. Ref: Sabiston 20th Ed. ; S...
Surgery
All India exam
5ba6e1a4-e250-4eb6-b7f5-dc26445d2227
Subepidermal bistreing is seen in all except ?
Pemphigus vulgaris
Dermatitis herpetiformis
Toxic epidermal necrolysis
Pemphigus
3d
multi
Ans:D. i.e. Pemphigus Causes of Subepidermal Blistering includes :Bullous pemphigoid, dermatitis herpetiformis, erythema multiforme, TEN, friction blisters.Causes of Intraepidermal Blistering includes :Acute eczema, varicella, herpes simplex, pemphigus
Skin
null
8d668755-ce52-4377-baf4-e721a00f1f24
Palmer's sign is pregnancy refers to (8-12 weeks):
Rhythmic contractions of uterus
Pulsations in the lateral fornix
Discoloration of vagina
None
0a
multi
Rhythmic contractions of uterus
Gynaecology & Obstetrics
null
170029ac-2a8e-43a6-ad55-e31059a55b20
Schizophrenia with the worst prognosis
Catatonic
Paranoid
Hebephrenic
Undifferentiated
2c
single
Hebephrenic schizophrenia Key Symptoms: Disorganized speech, behavior (often silly/ shallow) and flat or inappropriate affect Order of prognosis from good to bad in Schizophrenia: Catatonic > Paranoid > Undifferentiated > Hebephrenic > Simple Reference: Oxford Handbook of psychiatry; 3rd edition; Chapter 6; Schizophren...
Psychiatry
Schizophrenia and other psychotic disorders
1fa5ede1-d052-468a-8027-150d486cb0cc
Most common type of schizophrenia
Simple
Hebephrenic
Catatonic
Paranoid
3d
single
D i.e. Paranoid
Psychiatry
null
ab2a8fc4-5d06-4a45-95f9-bc98aed2b916
The drug most likely to be responsible for acute pancreatitis is :
Didanosine
Ketoconazole
Saquinavir
Zidovudine
0a
single
null
Pharmacology
null
94eba4f1-7251-4f74-bf7e-0ad3423fde77
Ideal speed for most rotary NiTi Instrument is
300-350 rpm
350-500 rpm
500-600 rpm
100-200 rpm
0a
single
Most endodontic rotary systems are used in the speed range of 300-350 RPM. Light speed is ued at 1200 rpm
Dental
null
2deca00a-f289-4105-931d-8d2019b354c2
Investigation of choice for Posterior urethral valves:
Micturating Cystourethrography (MCU)
Ultrasound
Intravenous Pyelography
Retrograde urethrography
0a
single
Ans. a (MCU). (Ref. Sutton Radiology 7th ed. 1017, 1061)- MCU is IOC for PU valve and VUR.Posterior urethral valves (PUV)# Varying degree of chronic urethral obstruction due to fusion and prominence of plicae colliculi, normal concentric folds of urethra.# Usually located in posterior urethra just distal to the level v...
Radiology
Genito Urinary System
d1c90183-37c3-433d-b217-fbc7b541d31c
A 25-year-old man is involved in an automobile accident with resultant injuries including bilateral closed femur fractures, left pulmonary contusion, and closed head injury. On post-injury day 4, significant upper gastrointestinal hemorrhage begins. Endoscopic examination reveals an area of confluent ulceration with bl...
Lavage of gastric contents with iced saline
Urgent total gastrectomy
Selective aerial infusion of vasopressin the left gastric aery
Inseion of Sangstaken-Blakemore balloon
2c
multi
Initial effos to control gastric hemorrhage consist of gastric lavage using warmed saline. Lavage serves to fragment existing clots and to remove any pooled blood, reducing fibrinolysis at bleeding sites. Over 80% of patients who present with upper gastrointestinal hemorrhage stop bleeding using this approach. Definiti...
Surgery
Stomach & Duodenum
4b000b25-970e-4448-8207-2fccf25dd4e1
Triangular relation of Elbow is maintained in
Fracture ulna
Anterior dislocation of Elbow
Posterior dislocation of Elbow
Supracondylar fracture
3d
single
D i.e. Supracondylar fracture
Surgery
null
1e4aa405-24ac-4dc2-abad-ebcd47e977d0
Vaginal defence is lost:
Within 10 days of bih
After 10 days of bih
During pregnancy
At pubey
1b
single
Vaginal pH: newborn infant -4.5 to 7 pubey -alkaline to acidic reproductive age -4 to 5.5 pregnancy -3.5 to 4.5 post menopausal -6 to 8 Acidity of vagina is because of doderlein's bacilli. It is a rod-shaped gram-positive bacillus which grows anaerobically on acid media. It appears in the vagina 3-4 days after bih and ...
Gynaecology & Obstetrics
Anatomy of the female genital tract
541a2af8-555d-4ada-a0a6-577b69d47ac6
Primary health centre was proposed under:
Srivastava committee
Bhore committee
Kaar Singh committee
None of the above
1b
multi
Bhore committee in 1946 gave the concept of primary health care centre as a basic health care unit. Ref: Park 22nd edition pg: 800.
Social & Preventive Medicine
null
5b073b29-c3e5-41f6-9964-ff2de8119acc
Natural habitat of Schistosoma (blood flukes) ?
Veins of the urinary bladder
Poal & pelvic veins
Vesical plexuses
All of the above
3d
multi
Ans. is 'd' i.e., All of the above
Microbiology
null
6ed275d2-a711-461f-beb1-aca540311498
A patient sustains a knife wound through the right fouh intercostals space, 2 cm to the right of the sternum. The area most likely penetrated by the knife is the
Right upper lobe of the lung
Right middle lobe of the lung
Right lower lobe of the lung
Right atrium of the hea
1b
single
The right border of the hea is approximately 1 to 2 cm to the right of the right border of the sternum; therefore, the knife probably did not hit the hea. The middle lobe of the right lung extends from the level of the fouh costochondral junction to the level of the fifth intercostal space. The middle lobe is most like...
Anatomy
Thorax
b7d9688e-4eb7-4d3a-ae88-01e1ac397d54
Duputryens contracture commonly affects: September 2005
Little finger
Ring finger
Middle finger
Index finger
1b
single
Ans. B: Ring Finger Dupuytren's contracture is more common among people with diabetes, alcoholism, or epilepsy. Dupuytren contracture, a disease of the palmar fascia, results in the thickening and shoening of fibrous bands in the hands and fingers. The ring finger is the one affected most commonly. It is usually limite...
Surgery
null
ba7c2757-ee9a-4c98-bfa1-acef6adfa8b6
Hemiparesis is NOT a feature of:
Carotid aery occlusion
MCA occlusion
AC A occlusion
Veebral aery occlusion
3d
single
Patients with veebral aery occlusion may present as posterior inferior cerebellar aery syndrome with cerebellar and brainstem signs such as dysahria, iplsilateral limb ataxia, veigo, nystagmus, ipsilateral Horner's syndrome, ipsilateral loss of pain and temperature of face, ipsilateral pharyngeal and laryngeal paralysi...
Medicine
null
2914f119-98dd-4c93-ac21-88e91f6c0480
Preterm baby with PDA, which is the least likely findings?
CO2 washout
Bounding pulses
Pulmonary hemorrhage
Necrotising enterocolitis
0a
single
Ans. is 'a' i.e., CO2 washout PDA in preterm neonate o In previous explanations I have explained that chances of spontaneous closure of PDA are higher in premature infants as there is no structural abnormality. However, you should keep in mind that this fact is true when we are comparing the spontaneous closure of PDA ...
Pediatrics
null
561f6314-6a70-44a7-9b05-4b60f7201797
Increased acetylcholinesterase in amniotic fluid indicates -
Open neural tube defects
Oesophageal atresia
Down syndrome
Edwards syndrome
0a
single
(A) (Open neural tube defects) (1998 - Nelson 19th)* Failure of closure of the neural tube allows excretion of fetal substances (a-fetoprotein , acetylecholinesterase) into the amniotic fluid, serving as biochemical and markers of a neural tube defects (NTD).* Prenatal screening of maternal serum of AFP in the 16th - 1...
Pediatrics
Miscellaneous
35cd4faf-f262-4883-9836-4de77f1a505b
15/F complains of anterior knee pain, increased on climbing stairs and getting up after prolonged sitting. Diagnosis is:
Chondromalacia patellae
Bipaite patellae
Plica syndrome
Patellofemoral ahritis
0a
single
Given scenario suggests diagnosis of Chondromalacia patellae Plica syndrome- anterior knee pain, clicking, clunking, and a popping sensation on patellofemoral loading activity such as squatting Patellofemoral ahritis will be seen at a later age and will have pain in all movements of knee. Bipaite patella is congenital ...
Orthopaedics
Neuromuscular disorders
d8d33903-6c01-46eb-926f-8903350eae35
Which of the following pain is not referred to ear
Pharynx
Teeth
Angle of TM joint
Vestibule of nose
3d
single
Reffered pain to ear: Benign ulcers or malignant lesions of the base of tongue tonsil pillars palate Ref: Dhingra 7e pg 435.
ENT
Ear
989f2093-2103-48b5-ab55-bcb551077201
Paget's disease of nipple is stained positive for:
CEA
S 100
Both of the above
None of the above
0a
multi
Paget's disease may be confused with superficial spreading melanoma. Differentiation from pagetoid intraepithelial melanoma is based on the presence of S-100 antigen immunostaining in melanoma and carcinoembryonic antigen immunostaining in Paget's disease. Surgical therapy for Paget's disease may involve lumpectomy, ma...
Surgery
null
6e84a2d0-8f9b-4eb1-9808-e6389dd7c02b
The following is true about term "New Families' -
It is variant of the 3-generation family
It is applied to all nuclear families of less then 10 years duration
It is variant of the joint family
It is applied to all nuclear families of less then 2 years duration
1b
multi
- all nuclear families of less then 10 years duration is termed as new families. - the concept is impoant in view of studies relating to family planning. Reference : Park's textbook of preventive and social medicine, 23rd edition, pg no:684 <\p>
Social & Preventive Medicine
Social science, Mental health & Genetics
91fc0a8a-7251-4962-823f-afb03cdf85ec
Which of these is not a derivative of 3rd pharyngeal/ branchial arch:
Lesser cornu
Greater cornu
Stylopharyngeus
Lower hyoid
0a
single
Ans. (a) Lesser cornuRef: Inderbir Singh's Embroyology, 7th ed. /119-120Lesser cornu of hyoid is derived from 2nd branchial arch.1st Branchial arch2nd Branchial arch3rd Branchial arch4th Branchial arch6th Branchial arch* Malleus and Incus* Maxilla* Mandible* Muscle of mastication* Stapes* Upper half of body of hyoid* L...
ENT
Larynx
69cda036-fe20-4d53-be80-5e563c9122f2
The following drug is effective in treatment of ptyriasis versicolor ?
Ketoconazole
Metronidazole
Griseofulvin
Chloroquine
0a
single
Ans. is 'a' i.e., Ketoconazole Pityriasis versicolor (Tinea versicolor) Tinea versicolor is a misnomer as it is not caused by dermatophyte; Pityriasis versicolor is more appropriate term. It is caused by a nondermatophyte fungus called Pityrosporum ovale (Malasezia furfur). It usually affects young adults. Clinical fea...
Skin
null
5a21646a-c5db-4e8d-b73b-8fc2d46f2fd6
Hypoxia due to the slowing of circulation is seen in which of the following?
Anemic hypoxia
Histotoxic hypoxia
Hypoxic hypoxia
Stagnant hypoxia
3d
single
Hypoxia is O2 deficiency at the tissue level. Traditionally, hypoxia has been divided into four types.Type of hypoxiaSignificanceHypoxic hypoxia The PO2 of the aerial blood is reduced.Anemic hypoxia The aerial PO2 is normal but the amount of hemoglobin available to carry O2 is reducedStagnant hypoxia The blood flow to ...
Anatomy
All India exam
6e5af7a0-f15a-4f05-b529-19195adbb0be
A male was brought unconscious with external injuries. CT brain showed no midline shift, but basal cistern were compressed with multiple small hemorrhages. Diagnosis is: AIIMS 06
Cerebral contusion
Cerebral laceration
Multiple infarcts
Diffuse axonal injuries
3d
multi
Ans. Diffuse axonal injuries
Forensic Medicine
null
11480ad5-d375-4976-80a6-81641180058a
Infectivity of HBsAg is best/commonly diagnosed by-
HBeAg
HbsAg
HBV DNA
Anti HBs Ag
0a
single
null
Microbiology
null
4d60298d-8c2e-45db-9a18-64bcc4a7dd18
Accuracy refers to:
Sensitivity
Specificity.
Both
Any of the above.
2c
multi
null
Dental
null
e875d41c-f9a2-4fb0-bd6a-308b7dc01472
A patient has Hb 6 gm% folic acid 82g/ml, vitamin B12 60 pg/ml, serum iron 180g/dl, and MCV-104.The diagnosis is -
Iron deficiency anaemia
Vitamin B12 deficiency
Folic acid deficiency
Pyridoxine deficiency
1b
single
null
Medicine
null
760f2023-6644-4361-8a2f-92b7ba531f54
Predisposing factors for coronary aery disease include, all Except:
Homocysteinemia
| Lipoprotein B
| Fibrinogen
| plasminogen activator inhibitors 1
1b
multi
Predisposing factors for coronary aery disease include an increased lipoprotein &;a&; and not lipoprotein &;6&;. REF: Harrison book of internal medicine 21ST EDITION
Medicine
All India exam
ec8bacc4-c74d-439f-b81a-d6b49b5ecd2c
Cell swelling is seen in all except?
Infection
Malignancy
Calcification
Hypoxia
2c
multi
Ans. (c) CalcificationRef: Robbiris pathology 9th ed. 140-41, 65* Cellular swelling may occur due to cellular hypoxia, which damages the sodium-potassium membrane pump; it is reversible when the cause is eliminated.* Cellular swelling is the first manifestation of almost all forms of injury to cells.* On microscopic ex...
Pathology
Cellular Pathology
2376676b-4585-44fe-b5e3-31b38eedd1f9
If during blood transfusion reaction develops in the form of incompatibility, the first thing to be done is
Stop the transfusion
Inj Hydrocortisone to be given
Inj Chlorpheneramine maleate to be given
Inj Frusemide to be given
0a
single
null
Surgery
null
fbafe949-e281-4310-bfab-53fe65e85921
(HIT)Head impulse test is used to diagnose?
Subarachnoid haemorrhage
Lhermite sign
Nuchal rigidity
Vestibular disease
3d
single
Option A & C ruled out as SAH presents with Nuchal rigidity. Option B- Sudden neck flexion causes shooting pain in the back which is feature of TABES DORSALIS. HIT test is a bedside technique used to diagnose reduction in vestibular function in one ear vs. the other. HINTS exam (Head Impulse, Nystagmus and Test for Ske...
Medicine
Headache And Migraine
857d7af4-f62c-45ee-bb60-ad6677925d4d
Epiphora & lagopthalmous following VII nerve injury is due to-
Failure of lacrimal pump
Increased lacrimal secretion
Nasolacrimal duct obstruction
None of the above
0a
multi
Ans. is 'a' i.e., Failure of lacrimal pump o Symptomatic epiphora following facial paralysis is most often associated with one or more of the following -i) Impairment of eyelid closure.ii) A compromised lacrimal pump.iii) Lower lid laxity
Ophthalmology
Intra Ocular Tumour
1544dd2d-cc15-4352-9bb3-002524216a59
Poor prognostic indicator of Pott's paraplegia
Early onset
Active disease
Healed disease
Wet lesion
2c
single
Ans. is 'c' i.e., Healed disease Prognosis of Pott's paraplegia Good Poor Degree Paial (only sensory or motor) Complete paraplegia (grade IV) Duration Shoer Longer (> 12 months) Type Early (acute) onset Late (chronic) onset Speed of onset Slow (insidious) Rapid (sudden) Age Younger Old General condition Good Poor Veebr...
Surgery
null
18221aab-d0e9-4194-98aa-3aad32aef0a0
A 21 year old student is found to have hyperthyroidism. She is counselled on treatment options including radioactive iodine and antithyroid medications. Carbimazole acts on which part of the thyroid hormone synthesis pathway?
Cleavage of thyroglobulin by proteolysis
Coupling of monoiodotyrosine (MIT) and diiodotyrosine (DIT) forming triiodothyronine CTsl and thyroxine (T4)
Dehalogenation of iodinated tyrosine to recycle iodide
Organification of iodide by thyroid peroxidase incorporating tyrosine forming MIT and DIT
3d
multi
Iodide is actively transported into follicular cells by a sodium/iodide transporter (Fig. 18.6). Pendrin is found at the apical membrane, where it transports iodide into colloid. A defect in this transporter underlies Pend red's syndrome (congenital hypothyroidism and deafness). Thyroid peroxidase catalyses the convers...
Medicine
null
9d839c27-fff0-49c5-8c46-f245d208d6bb
Sickle cell anemia is the clinical manifestation of homozygous genes for an abnormal haemoglobin molecule. The event responsible for the mutation in the B chain is -
Inseion
Deletion
Non disj unction
Point mutation
3d
single
D i.e. point mutation
Biochemistry
null
82e657d9-2911-4d2e-a004-b0a4c480a741
As compared to morphine, methadone is -
Superior analgesic and inferior hypnotic
Superior hypnotic and inferior analgesic
Superior analgesic and superior hypnotic
Inferior analgenic and inferior hypnotic
0a
single
Ans. is 'a' i.e., Superior analgesic and inferior hypnotic I mg of methadone can be substituted for 4 mg of morphine. Methadone is less hypnotic than morphine (sedative action is less intense).
Pharmacology
null
5616e3ae-1210-4582-bfe8-e538300e2559
Drug of choice for primary syphilis is :
Ampicillin
Benzathine penicillin
Erythromycin
Tetracycline
1b
single
null
Pharmacology
null
aafd05ba-1121-4f53-b1cf-44ec4c586daa
Antiparkinson's drug known to cause cardiac valvular fibrosis is
Levodopa
Ropinirole
Pramipexole
Pergolide
3d
single
Pergolide, ergot derivative, directly stimulates both D1 and D2 receptors. It has been widely used for parkinsonism but is no longer available because its use has been associated with the development of valvular hea disease.Reference: Katzung Pharmacology; 13th edition; Chapter 28; Pharmacologic Management of Parkinson...
Pharmacology
Central Nervous system
368161c1-15ef-4d0b-986c-ff62ca444eb4
Which of the following is a Rho kinase inhibitor? (AIIMS November.2013. May 2013. November 2012)
Fasudil
Ranolazine
Amiloride
Nicorandil
0a
single
Ans. a. Fasudil (Ref: Katzung 11/e p203; Harrison 19/e p1590, 18/e p2011)Fasudil is a Rho kinase inhibitor leading to vasodilatation.FasudilRho kinase (protein kinase)-Vasocontrictor signalFasudil is a Rho kinase inhibitorQ leading to vasodilatation.New Anti-Anginal DrugsFasudilRho kinase inhibitorQTrimeiazidine* Metab...
Pharmacology
Anti-Anginal
9d4a8b6b-e3fc-4eac-92bb-08cc589c7b54
Efficacy of new drug A is compared with an existing drug B in:
Clinical trial phase I
Clinical trial phase II
Clinical trial phase III
Clinical trial phase IV
2c
single
Phase Unit of study Purpose PRECLINICAL PHASE Lab experiments Animals Pretesting CLINICAL PHASE Typical No. of patients Phase 0 Healthy human volunteers Micro - dosing Phase I Healthy human volunteers Safety and non - toxicity profile 10 to 30 usually healthy volunteers Phase II Patients Effectiveness Fewer than 100 Ph...
Social & Preventive Medicine
RCT, Trials
84379f6e-080b-4991-8a2d-0b7e54c4ffb6
Which is not true about Cryptococcus neoformans
Grows at 37 o C
Grows on sabouraud's agar
Polysaccharide capsule
Urease negative
3d
multi
It hydrolyses urea which differentiates Cryptococcus neoformans from non-pathogenic cryptococcus. Ref: Textbook of Microbiology, Ananthanarayan and Paniker; 9th edition
Microbiology
mycology
2b315cc8-deef-4b18-93e4-f6f6d4985b28
Most common site involved in Otosclerosis is
Foot plate stapes
Malleus head
Incus
Ear drum
0a
multi
(A) Foot plate stapes # Stapedial Otosclerosis:> Stapedial otosclerosis causing stapes fixation and conductive deafness is the most common variety.> Here lesion starts just in front of the oval window in an area call 'fissula ante fenestram'.> This is the site predilection (anterior focus).> Lesion may be behind the ov...
ENT
Miscellaneous (E.N.T.)
4b5c6a1c-cb79-4c70-be72-40389732c847
True about NPCDCS is all except
Separate centre for stroke, DM
Implementation in some 5 states over 10 district
CHC has facilities for diagnosis and treatment of CVD, Diabetes
Day care facilities are available at subcentre
2c
multi
Ans. c. CHC has facilities for diagnosis and treatment of CVD, Diabetes The NPCDCS program has two components viz. (i) Cancer and (ii) Diabetes, CVDs and Stroke. These two components have been integrated at different levels as far as possible for optimal utilization of the resources. The activities at State, Districts,...
Social & Preventive Medicine
null
01e7819e-9e1f-45a9-9efb-47c58351c08b
The court which can sentence imprisonment for a maximum of 10 years
Chief Judicial Magistrate
First class Judicial Magistrate
Assistant Sessions court
Additional Sessions court
2c
single
Answer: c) Assistant Sessions court (KS NARAYAN REDDY 33rd ED P-7)COURTS OF LAWCourtImprisonmentFineSupreme courtAny sentenceAny amount of fineHigh courtAny sentence authorized by lawAny amount of fineSessions courtAny sentence authorized by law (but death sentence must be confirmed by High court)Any amount of fineAssi...
Forensic Medicine
Law & Medicine, Identification, Autopsy & Burn
8540bfe2-1f5b-40e0-97bd-ad1409247046
Where are the dentists feet during any procedure when four handed dentistry is practiced
On the stool support rim
On the floor
On the dental chair base
Where ever is convenient
1b
single
null
Dental
null
a9e6e097-c028-439a-ae33-13d34946a4c3
Which of the following is the most significant risk factor for postoperative nausea and vomiting
Female gender
Smoking
Age over 60 years
Surgery on the breast
0a
single
Postoperative nausea and vomiting is most common in women, young people, and patients who have received opioids during surgery. Surprisingly, perhaps the one advantage of smoking is that smokers tend to have less postoperative nausea and vomiting than nonsmokers. Similarly, the incidence of postoperative nausea and vom...
Anaesthesia
Preoperative assessment and monitoring in anaesthesia
43750f16-4629-47f4-8a9d-ce18c65bd8a8
All are symptoms of molar pregnancy except:
Amenorrhea
Symptoms of Hypothyroidism
Abnormal vaginal bleeding
Expulsion of grape like vesicles
1b
multi
Ans: B (Symptoms of Hypothyroidism) Ref: Shaw's textbook, of gynaecology 15th ed. Pg 253Explanation: (See the following tabletCLASSIC CLINICAL FEATURES OF COMPLETE MOLEAmenorrhoea of 8- 12 weeksAbnormal vaginal bleedingLower abdominal painHyperemesis gravidarumFeatures of early onset preeclampsia (< 20 weeks)Uterine Ht...
Gynaecology & Obstetrics
Miscellaneous (Gynae)
fc5ebc0f-59d5-4a69-8f69-5c435154cfba
Which of the following passes through the foramen magnum EXCEPT
Veebral Aery
Sympathetic chain
Xlth cranial nerve
Internal carotid Aery
0a
multi
A i.e Veebral Aery
Anatomy
null
803b132f-2cfb-48d7-8541-0c85eaa73d25
Subaortic stenosis is not associated with?
Ventricular septal defect
Aortic regargitation
Patent ductus arteriosus
Coarctation of aorta
1b
single
null
Medicine
null
b84bbadc-bb1f-4519-87c6-921699366010
A 85 year old female developed multiple blisters on trunk and thighs. Nikolsky's sign negative. The lesions came on and off. The most probable diagnosis is NOT RELATED-DERMATOLOGY
Pemphigus vulgaris
Bullous pemphigoid
Lichen planus
Lepra reaction
1b
single
.
Pharmacology
All India exam
4c9a0ca7-c057-4f5e-8a75-c19d6227bd66
Amyl nitrite is used as antidote in which poisoning?
Cyanide
Cholinesterase
Benzodiazepine
Barbiturate
0a
single
Ans. is 'a' i.e., Cyanide
Forensic Medicine
null
fbfa1bbc-002e-4313-9ed8-eb3a6a9dffb8
Hypoglycemia is an impoant feature of which of the following condition?
Hypoparathyroid
Addison disease
Pheochromocytoma
All of the above
1b
multi
.
Medicine
All India exam
be6a8fe5-fe54-4dc5-85b7-35be03560c68
There is no cyanosis in severe anemia because -
Certain min. amount of reduced Hb should be present
In anemia, O2 saturation increases
Hypoxia stimulates erythropoietin production
O2 hemoglobin curve shifts to right
0a
single
Ans is 'a' i.e. Certain min. amount of reduced Hb should be present o Cyanosis is a blue coloration of the skin and mucous membranes due to the presence of >5g/dl reduced hemoglobin in blood vessels near the skin surface. Now since in anemia the total amount of hemoglobin is decreased, the amount of reduced Hb to produ...
Pathology
Misc. (R.B.C)
0fff791e-7073-496c-8af2-e92d78482a2d
A 65 year old lady underwent mastectomy for Carcinoma breast. Later she developed frontal headache, pain in temple region and around eye. Her ESR is 55 mm/hour. What is the most probable diagnosis?
Cavernous sinus thrombosis
Meningeal metastasis
Frontal sinusitis
Giant cell aeritis
3d
single
GIANT CELL AERITIS Headache, scalp tenderness, visual symptoms, jaw claudication, or throat pain The temporal aery is usually normal on physical examination but may be nodular, enlarged, tender, or pulseless Blindness Results from occlusive aeritis of the posterior ciliary branch of the ophthalmic aery Ischemic optic n...
Medicine
JIPMER 2019
218c9ff6-832f-4123-9dda-4f9ce289e437
The most effective means of Limiting applied loads to abutment teeth in a distal extension partial denture is by
Using a stress breaker
Using acrylic replacement teeth
Splinting abutments to adjacent teeth
Maintaining a stable base tissue relationship
3d
single
null
Dental
null
496ee96f-286c-4796-8490-20abc3e6f333
Continuous murmur is present in
cardiomyopathy
MS
PDA
cardiac tamponade
2c
single
A continuous murmur is predicated on a pressure gradient that persists between two cardiac chambers or blood vessels across systole and diastole.The murmurs typically begin in systole, envelop the second heart sound (S 2 ), and continue through some portion of diastole. They can often be difficult to distinguish from i...
Medicine
null
999fea48-cf9d-495e-82de-dc137ae28888
Function of endonucleases:-
Cut DNA at specific DNA sequences
Enhancers
To find out antibiotic resistances
To point out the coding regions
0a
single
Endonuclease Exonuclease Cut in between the DNA sequence Cut from the sides either from 5' or from 3' side Cut ds DNA Cut ss & ds DNA
Biochemistry
Basics of DNA
9e7fc1f1-55b9-433b-8ccf-23e740cd68d4
Which is a clean surgery
Hernia surgery
Gastric surgery
Cholecystectomy
Rectal surgery
0a
single
.In adults surgical management includes * It includes herniotomy, i.e. excision of hernial sac and herniorrhaphy (strengthening of the posterior wall of inguinal canal either by repair or mesh). Precipitating causes should be treated first, like TURP for BPH, dilatation of stricture urethra, treatment of chronic bronch...
Surgery
Urology
9a6541ad-5180-499d-8a89-1cc8a796cefb
Which of the following drugs is supposed to prevent congenital neural tube defects -
Thiamine
Riboflavin
Folic acid
Pyridoxine
2c
single
Folic acid plays a role in synthesis of nucleic acids. It is needed for normal development of blood cells in the marrow. REF. PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICAL 21ST EDITION. PAGE NO - 620
Social & Preventive Medicine
Nutrition and health
c681b4b8-3daf-4407-9d52-b4e18032808f
Pressure of normal uterine contractions is between 190-300 units. Which unit is being referred to here?
Montevideo units
mm of Hg
cm of water
Joules/kg
0a
single
Ans. is a, i.e. Montevideo unitsRef Williams Obs, 23/e, p 4371 montevideo unit = Intensity of constraction x number of contractions in 10 mins.Montevideo unit is to define uterine activity.As per this:Clinical labour usually commences when uterine activity reaches values between 80-120 Montevideo units (This translates...
Gynaecology & Obstetrics
Normal Labour
43c59653-c0aa-498b-9bb4-8c0c3276735b
LES pressure is decreased by all except:
Alcohol
Gastrin
Fat
Peppermint
1b
multi
Lower Esophageal Sphincter (LES) Pressure Decreased by Increased by Prostaglandin E1 and E2, Progesterone Theophylline Barbiturates, Diazepam, Dopamine CCB, Atropine, Nitrates Chocolate, Coffee Alcohol, Pippermint Smoking, Fat Bombesin, Angiotensin II PP, Substance P, Motilin Gastrin Antacids Cholinergics Domeperidone ...
Surgery
Esophagus
9308e6f7-2efe-4f52-b2dd-858fb18104c4
Treatment of choice for aplastic anaemia is
Blood transfusion
Oxymethalone
Bone marrow transplantation
Azathioprine
2c
single
The prognosis of severe aplastic anemia managed with suppoive therapy is only poor and more than 50% of people die, usually in the first year. The curative treatment for patients under 35 years of age is allogenic hematopoietic stem cell transplantation if there is an available sibling donor. Older patients and those w...
Medicine
Haematology