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135
b3abeea7-7099-43a6-a7a7-511dbc41f7c5
Involvement of the joints of hand is relatively uncommon in which of following ahritis?
Ankylosing spondylitis
Reactive ahritis
Psoriatic ahritis
Rheumatoid ahritis
0a
single
Joints involved in ankylosing spondylitisAnkylosing spondylitis primarily affects the axial skeletonThe disease usually begins in the sacroiliac joints and usually extends upwards to involve the lumbar, thoracic, and often cervical spineIn the worst cases, the hips or shoulders are also affected. The hip joint is the m...
Orthopaedics
All India exam
d7721e32-bf89-4bb7-9a03-67448742bf3d
The best investigation for colorectal carcinoma -
Exfoliative cytology
Air contrast barium enema
Ultrasound
Colonoscopy and biopsy
3d
single
null
Surgery
null
0d6277b2-8c3a-4174-82a1-09b4ded897c0
Which of the following is not true about ACE inhibitors?
Used in asthma
Increase quality of life
Postural hypotension is seen
Na level decrease
2c
multi
null
Pharmacology
null
0bd35e48-62db-4c8f-ae9c-64648f045f98
Asymptomatic gonorrhoea in females is due to infections of :
Vagina
Urethra
Endocervix
Fundus
2c
single
Endocervix
Gynaecology & Obstetrics
null
5df9ef5c-32ce-407f-9604-c87a2e83373d
Orphan drugs are:-
Commercially easy to obtain
Drugs to treat rare diseases
Developed with an intention of monetary gain
All of the above
1b
multi
* Orphan drugs are defined as the medicines which are unlikely to be developed by pharmaceutical industry due to economic reasons but which respond to public health needs. * Orphan drug is developed specifically to treat a rare medical condition (affecting fewer than 200,000 people), the condition itself being referred...
Pharmacology
Pharmacodynamics
a10e555a-800e-466d-8bf6-545e33478772
Renal collar which surrounds the aoa has its two limbs split by -
Left renal vein
Left renal aery
Isthumus of horseshoe kidney
All of the above
0a
multi
Ans. is 'a' i.e., Left renal vein The left renal vein normally passes anterior to the aoa to join the I.V.C. However sometimes the left renal vein may divide and send one limb anterior and one posterior to the aoa to reach the inferior vena cava k/a venal collar representing persistence of embryological state. Also rem...
Surgery
null
5a6e37a7-2877-41c6-b075-b507cfa83f93
Which of the following drug is an Immunostimulant?
Prednisolone
Levamisol
Cyclosporine
Thalidomide
1b
single
(Ref: Goodman & Gliman 11/e p1422) All other drugs listed in the options posses immunosuppressant propeies.
Pharmacology
Other topics and Adverse effects
5b7f5e6f-870b-4690-a5ec-3a7dd3cd48cc
OCP's are contraindicated in A/E :
Smoking 35 years
Coronary occlusion
Polycystic ovarian ds
Cerebro vascular ds
2c
single
Ans. is c i.e. Polycystic ovarian disease
Gynaecology & Obstetrics
null
41495777-2894-4317-b625-a955be5396d1
Japanese encephalitis vaccine is:
Live attenuated
Inactivated toxoid
Cellular fractions
Combined
0a
single
Ans. (a) Live attenuatedRef : K. Park 23rd ed. / 286-87* JE vaccine is a live attenuated vaccine. It is available in killed vaccine form also.* Strain: SA 14-14-2- liveNakayama strain- killed* One dose of JE vaccine is given at 16-24 months of age.Also Know* MC live vaccine used: BCG* MC killed vaccine used: Pertusis* ...
Social & Preventive Medicine
Principles of Immunization and Vaccination
fd2816b5-6580-4168-b2ea-189524732d12
Which of the following is not a sign of reversible cell injury?
ATP depletion
Cell shrinkage
Fatty acid deposition
Reduction of phosphorylation
1b
single
Ans. (b) Cell shrinkage(Ref: Robbins 9th/38;8th/pg 17)Features of reversible cell injury seen in light microscopy are cellular swelling and fatty change.Cell shrinkage is a feature of apoptosis (cell death)
Pathology
Cellular Pathology
34e4535e-4967-4484-ab47-9d75d24e726b
The tooth bud for the third molar is initiated at about the age of:
6th month I.U
1st year of life
2nd year of life
8th year of life
3d
single
null
Dental
null
f95a3179-0ca0-465e-9de2-32944758f009
Most common site for minor salivary glands tumor is:
Lip
Floor of oral mucosa
Hard palate
Gingivolabial folds
2c
single
null
Surgery
null
2f844c59-f5e0-4072-9d19-6bd4baca6a37
Wormian bones are not noted in -
Fibrous dysplasia
Osteogenesis inperfecta
Cretinism
Rickets
0a
single
Wormian bones Wormian bones are extra bone pieces that occur within a suture in the cranium. These are irregular isolated bones which appear in addition to the usual centres of ossification of the cranium. They occur most frequently in the course of the lambdoid suture. Causes of Wormian bones (Mnemonic - PORKCHOPS) ...
Orthopaedics
null
e3bf752b-0339-40d5-950b-412f182cba4c
Hidradenitis suppurativa is a disease of:
Eccrine sweat glands
Apocrine sweat glands
Kaposi sarcoma
Hair follicles
1b
single
Hidradenitis suppurativa is chronic inflammation and secondary infection of apocrine sweat glands Aetiology : Unknown ,common in post-pubeal females, maybe inherited(AD in some families) C/F Rare chronic painful skin condition with inflammation of the skin at sites rich in apocrine glands (axilla, groin, natal cleft) O...
Dental
Disorders of sebaceous and sweat glands
3ee97e14-cca4-4712-8080-8611d71adf61
Positive G effect ?
Red out
Black out
Increased cerebral aerial pressure
Increased cardiac output
1b
single
Ans. is 'b' i.e., Black outEffects of positive G:Venous return decreases --> hence, cardiac output decreases.Blood rushes towards lower limbs --> hence increased pressure in lower limb vessels.Blood is drawn away from upper body --> hence decreased cerebral aerial pressure.At very high positive G:Difficulty in blood fl...
Physiology
null
543807e9-a25d-44e2-bd9f-f2ae3c46ee5c
All of the following are preschool age problems EXCEPT: March 2013 (b, c, d)
Sleeping disorde
Temper tantrum
Pica
Stuttering
1b
multi
Ans. B i.e. Temper tantrum Temper tantrum reaches its peak point during second and third year of life and gradually subsides in between 3-6 years as the child learns to control his negativism and complies to the request of others
Pediatrics
null
a32e6674-ea4e-47de-b214-46fc0e632f3e
Squamous cell carcinoma spreads commonly via -
Implantation
Hematogenous spread
Lymphatic spread
Trancoelomic spread
2c
single
null
Pathology
null
e8e0a6a1-2652-4e75-9be0-5e79dbf0aa55
Function of UGA codon -
Initiates transcription
Translates
Terminates protein synthesis
None
2c
multi
Ans. is 'c' i.e., Terminates protein synthesis o Termination (stop/nonsense) codons signal to terminate the translation. These are 3 stop codons UAA, UGA and UAGo Initiation codon - AUGo Stop codons (termination codons or nonsense codons) - UAA, UGA, UA G
Biochemistry
Chemistry of Nucleotides
d37f7d4a-22fd-4b56-80cd-ef86d68c3b84
Most common site of intracranial metastasis is from primary carcinoma of
Breast
Lungs
Stomach
Testes
1b
single
MC brain tumor is metastasis,arising from - (1) Oat cell Ca lung/small cell Ca lung (2) Ca Breast (3) M. Melanoma MC 1deg Brain tumour- Glioma MC benign brain tumour - Meningioma
Medicine
FMGE 2018
a1e12ebc-5433-4c38-949f-df711d200c26
Regarding S3 heart sound all are true except
May be physiological
Due to early diastolic filling of ventricles
S3 is heard in acute MR
Seen in Conditions associated with increased preload
2c
multi
S3 is heard in chronic MR (not in acute MR)
Medicine
null
49c23a01-6c83-4c86-9fad-c1a1295940a7
A 65-year-old diabetic woman develops weakness on the left side of the face, right arm,and right leg. She also has diplopia on left lateral gaze. What is the site of lesion?
Right pons
Left pons
Right midbrain
Left midbrain
1b
single
Weakness on the left side of the face Weakness of the right sides of arm and leg | Crossed hemiplegia / Millard gubler syndrome. Pontine stroke. I/L 6th N. palsy- Diplopia on looking laterally I/L 7th N. palsy- facial paralysis but sensations not affected Coicospinal tract damage in pons will lead to C/L hemiplegia in ...
Medicine
Stroke and TIA
bab08deb-206d-41e4-b4a6-00dd1a34e9d6
Buerger's Disease is
Non - progressive
Segmental
Non - inflammatory
Atherosclerotic
1b
single
Buerger's Disease is non atherosclerotic inflammatory disorder involving medium sized and distal vessels. It is segmental, progressive , occlusive, inflammatory disease.
Surgery
null
56c78e1f-4067-46a8-80dc-3b3c2cac3b08
Most common nerve to be damaged in dislocation of shoulder is :
Axillary nerve
Radial nerve
Median nerve
Musculocutaneous nerve
0a
single
A i.e. Axillary Nerve
Surgery
null
08b89b55-502f-4d82-95c0-a2212e1270c4
Most common cause of stridor in infant and young children –
Abductor palsy
Croup
Laryngomalacia
Epiglottitis
2c
single
Laryngomalacia is the most common congenital laryngeal anomaly. It is the most common cause of stridor in infants and children.
Pediatrics
null
30158fed-b58e-4230-83e7-6b7c2a0b3007
Mallory denk bodies are seen in all except
Wilson's disease
Alcoholic fatty liver disease
Non alcoholic fatty liver disease
Hemochromatosis
3d
multi
Mallory denk bodies are not seen in Hemochromatosis and 2o biliary cirrhosis.
Pathology
null
3f8bd29d-073d-4c79-9365-58edb62cd041
Which of the following statement is not true about NSAIDs
Acetylsalicylic acid is an Irreversible inhibitors of Cox enzyme acetylsalicylic acid is an Irreversible inhibitors of Cox enzyme
Acetylsalicylic acid reduces in Vivo synthesis of prostaglandins
Its clearance is independent of Plasma concentration
Antiplatelet effect of low dose aspirin is related to pre systemic Cox inhibition
2c
multi
Acetylsalicylic acid (asprin) is an Irreversible inhibition of COX enzyme. IT results in inhibition of prostaglandin and TX synthesis at low doses for (40 to 325 milligrams) it exes antiplatelet action. this drug shows saturation kinetics at high doses that is kinetics changes from first order to zero order. therefore ...
Pharmacology
Autacoids
e8cd6b5a-5056-4fd4-85ab-444fa290928d
Rothera&;s test used for detection of
Proteins
Glucose
Fatty acid
Ketones
3d
single
The presence of ketosis can be established by the detection of ketone bodies in urine by Rothera&;s test.Rothera&;s test: Saturate 5 mL of urine with solid ammonium sulfate. Add a few drops of freshly prepared sodium nitroprusside followed by 2 mL of liquor ammonia along the sides of the test tube. Development of a pur...
Biochemistry
miscellaneous
c8f2f6ca-4e81-4d34-b7c4-b5e51d8632c1
A man weighing 70 kg has a hematocrit of 45%. What would he his approximate plasma volume?
2310 mL
2695 mL
2890 mL
3080 mL
3d
single
Ans. (d) 3080mL(Ref: Ganong Review of medical physiology, 21st ed p.2)8% of body weight is blood volumeSo, here for 70 kg man, Blood volume is 5.6 Litres (70*8/100)Blood Volume = Plasma volume/1-hematocritSo, Plasma volume = Blood volume*(1-hematocrit)Here, Plasma volume =5.6*(1-0.45)=3080mL
Physiology
General
813abbf9-2842-4fd0-ab21-ef863eb9bdb1
Median nerve supplies all muscles of the thumb except -
Abductor-pollicis-brevis
Flexor-pollicis-brevis
Opponens pollicis
Adductor pollicis
3d
multi
Median nerve supply in hand -        Flexor pollicis brevis -        Opponens pollicis -        Abductor pollicis brevis First two lumbricals Adductor pollicis is supplied by Ulnar nerve
Anatomy
null
ab8aa60d-3032-4590-9eb6-b432d5e25e6e
Secondary glaucoma in early stage of herpes zoster ephthalmicus occurs due to:
Trabeculitis
Iridocyclitis
Haemorrhagic hypopyon
Hypersecretion of aqueous humour
0a
single
Ans. Trabeculitis
Ophthalmology
null
ee472006-4c8f-4dc1-baf6-78e0b5e72034
Sodium content in mmol/L in WHO oral rehydration solution is -
20
80
90
111
2c
single
Ans. is 'c' i.e., 90
Pediatrics
null
5f4d2928-eff3-400e-a5a9-e17f6a9cb585
Division of long thoracic nerve results in
Inability to retract the scapula
Wasting of pectoralis major muscle
Weakness of adduction of humerus
Winging of scapula
3d
single
Nerve to serratus anterior is also called long thoracic nerve(C5,C6,C7). A)Serratus anterior muscle along with the pectoralis minor pulls the scapula forwards around the chest wall to protract the upperlimb. B)The fibres inseed into the inferior angle of the scapula pull it forwards and rotate the scapula so that the g...
Anatomy
Thorax
05bcd2ff-0b8e-460c-932c-e349153f7419
Epidemic dropsy is caused by
Sanguinarine
Ergot
Alkaloid
BOAA
0a
single
Ans. (a) Sanguinarine
Social & Preventive Medicine
Nutrition and Health
47cd7810-d31f-4b29-979b-45635195fe40
Patient is having scanty, foul smelling discharge from middle ear, develops fever, headache and neck rigidity. CT of the temporal lobe shows a localized ring enhancing lesion, which of the following is least likely cause of this condition?
S. aureus
Pseudomonas
S.Pneumoniae
H. influenza
3d
single
Commonest organisms in otogenic brain abscess include gram negative (Proteus, E coli, Pseudomonas) and anaerobic bacteria along with Staphylococcus and Pneumocci. H. Influenza infection is a rare cause of otogenic abscess.
ENT
null
232792cb-b1de-4aab-84f7-ef28f7110972
A 36-year-old woman has a cough and fever for 1 week. On physical examination, her temperature is 38.3deg C. She has diffuse crackles in all lung fields. A chest radiograph shows bilateral extensive infiltrates. CBC shows hemoglobin, 13.9 g/ dL; hematocrit, 42%; MCV, 89 mm3; platelet count, 210,000/mm3; and WBC count, ...
Chronic myelogenous leukemia
Hairy cell leukemia
Hodgkin lymphoma, lymphocyte depletion type
Leukemoid reaction
3d
multi
Marked leukocytosis and immature myeloid cells in the peripheral blood can represent an exaggerated response to infection (leukemoid reaction), or it can be a manifestation of chronic myelogenous leukemia (CML). Normal maturation of myeloid cells in the marrow rules out CML. Although not provided in this case, a leukoc...
Pathology
Blood
35234bb9-1aa3-4cff-88ea-2b7f3625db1e
Secondary prevention is applicable to ?
Causal factors
Early stage of disease
Late stage of disease
None of the above
1b
multi
Ans. is 'b' i.e.,Early stage of disease Primordial prevention - Before risk factor present.Primary prevention - Before onset of disease (risk factor present).Secondary prevention - In early stage of disease.Teiary prevention - Late stage of disease.
Social & Preventive Medicine
null
ccc6cd04-a065-4601-8550-136e30fffa03
A leukemia patient who has undergone multiple courses of chemotherapy develops herpes simplex encephalitis. Which of the following would you expect a CT scan of the patient's brain to show?
Generalized volume loss
Volume loss selectively in the basal ganglia
Volume loss selectively in the brainstem
Volume loss selectively in the temporal and frontal lobes
3d
single
Herpes simplex can cause a necrotizing, hemorrhagic acute encephalitis that may rapidly produce death. The encephalitis characteristically involves the lower poions of the cerebral coex, notably the temporal lobes and the base of the frontal lobes, possibly because the infection spreads from the oropharynx. Ref: Ropper...
Medicine
null
db6a4fc9-b443-4043-aaf9-e364faf7a187
Diarrhoea syndrome in an AIDS patient can be d/t – a) Rota virusb) Cryptosporac) Adenovirusd) E. soli
ab
a
ad
bc
0a
single
Agents commonly causing diarrhea in HIV patient. Rota virus                    Isospora Cryptosporidium    Cyclospora Microsporidium Giardia Lambi    Bacterial pathogens
Pediatrics
null
984a8b25-b8c4-4aae-bfb6-625be5d28ca7
Position that is least likely possible by means of bilateral saggital split osteotomy is
Advancement
Set back
Rotation
Transverse
3d
single
null
Surgery
null
c4bd1268-abae-4f12-bb8e-82a2cf060c4d
Physiological jaundice of newborn may be managed by all except -
Metalloporphyrin
Phenytoin sodium
Phototherapy
None of the above
1b
multi
Ans. b (Phenytoin sodium). (Ref. Nelson Textbook of Pediatrics 17th ed., 593, 597) # Jaundice during the 1st 24 hrs of life warrants diagnostic evaluation and should be considered to be due to hemolysis until proved otherwise. Septicemia and intrauterine infections such as syphilis, cytomegalovirus, and toxoplasmosis s...
Unknown
null
992646b8-2d5b-4a85-b058-30ffb6b3511f
1, 25 (OH)2 Cholecalciferol is formed in-
Skin
Liver
Spleen
Kidney
3d
single
25-hydroxy Cholecalciferol is formed in liver Whereas 1, 25 (OH)2 Cholecalciferol is formed in kidneys. Additional edge on synthesis of Vitamin D: Activation of 7-dehydro cholesterol by UV light in skin produces Cholecalciferol 25-hydroxylation in liver to form 25-hydroxy cholecalciferol 1-alpha- hydroxylation in kidne...
Biochemistry
Vitamins and Minerals
41a747eb-3827-4dcf-bb4e-6090f9b704b5
Most common cause of obstruction in atrophic rhinitis is:
Excessive formation of crust
Polyp
Synechiae
Hypertrophy of turbinate
0a
single
(a) Excessive formation of crust(Ref. Cummings, 6th ed., 695)The excessive crusting leads to nasal obstruction in spite of roomy cavities.On removal of crusts there is bleeding. But there is no synechiae formation. There is no polypoidal change .
ENT
Rhinitis
b1d4887d-8229-4af1-89e6-a435e4cc09e2
Which of the following does not cause hemorrhagic conjunctivitis –
Adenovirus
Coxsackie – 24
Enterovirus – 70
Papilloma virus
3d
single
Hemorrhagic conjunctivitis is caused by picornaviruses (Enterovirus - 70, coxsackievirus A24) and sometimes Adenovirus type 11.
Ophthalmology
null
21e9a60d-8b45-4410-bfbc-1f78b4219f99
A patient with acute leukaemia is admitted with febrile neutropenia. On day four of being treated with broad-spectrum antibiotics, his fever increases. X-ray chest shows bilateral fluffy infiltrates. Which of the following should be the most appropriate next step in the management
Add antiviral therapy
Add antifungal therapy
Add cotrimoxazole
Continue chemotheraphy
1b
multi
Cotrimoxazole is an antibiotic. As the patient is immunocompromised, most probable oppounistic infection is a fungal infection. And X-Ray shows fluffy infiltrates is suggestive of fungal infection. So antifungals are to be added. Ref: Textbook of Microbiology, Ananthanarayan and Paniker; 9th edition
Microbiology
mycology
d74d4814-098b-4866-8117-50149c5a9e50
A population is divided into relevant subgroups and random sample selection is done from each of the subgroups. This is which type of sampling method?
Systematic random sampling
Stratified random sampling
Simple random sampling
Cluster sampling
1b
single
- in stratified random sample, the sample is deliberately drawn in a systematic way so that each poion of the sample represents a corresponding strata of the universe. - this method is paicularly useful where one is interested in analysing the data by a ceain characteristic of the population. Reference : Park's textboo...
Social & Preventive Medicine
Biostatistics
197c922c-6f02-4ff8-9629-2e82f40864a8
In thin basement membrane disease, the defect is in
a1 and a2 chains of type IV collagen
a3 and a4 chains of type IV collagen
a1 and a2 chains of type VI collagen
a3 and a4 chains of type VI collagen
1b
single
TBM disease (also known as benign familial hematuria and thin basement membrane nephropathy) is, along with IgA nephropathy, the most common cause of blood in the urine without any other symptoms. The only abnormal finding in this diseaseis a thinning of the basement membrane of the glomeruli (filters) in the kidneys. ...
Pathology
Urinary tract
36bb2006-8baf-4b25-bb66-d1bb860b8539
A newborn presenting with intestinal obstruction showed on abdominal X-ray, multiple air fluid levels. The diagnosis is not likely to be-
Pyloric obstruction
Duodenal atresia
Illeal atresia
Ladd \\ s bands
0a
single
A i.e. Pyloric obstruction
Radiology
null
ade5ddec-73fa-487b-9958-4e76ff78a830
Anti-neutrophil cytoplasmic antibodies (ANCA) is seen in
Rheumatoid arthritis
Diabetes mellitus
Wegener’s Granulomatosis
Churg-Strauss syndrome
2c
single
PR3-ANCAs are also present in up to 95% of cases; they are a useful marker of disease activity and may participate in Wegener’s granulomatosis.
Pathology
null
83939c0a-197b-440a-a8f8-7e37f4f33371
Patient with jaundice and white stools. Which of the following enzymes is not raised
5' nucleotidase
Alkaline phosphatase
Glutamate reductase
Gamma glutamyl transpeptidase
2c
single
Large increase in gamma glutamyl transferase and ALP ours biliary obstruction (Davidson; page 929) 5&;nucleotidase rise parallels ALP but more specific for diseases of hepatic origin (Harsh mohan page 594)
Medicine
G.I.T
b8b6cb77-cdd4-4633-a890-ee94c0feb74c
Least clearance is for among these
Glucose
Inulin
Urea
Creatinine
0a
single
Glucose is completely reabsorbed in proximal tubules. So its clearance is zero.
Physiology
null
a6bee775-12c8-4675-a3f2-15c51cd3990d
Characteristics of glycoprotein:
Protein linked with glycosidic bond
Core protein
Sugar residues are long in carbohydrate poion of glycoprotein
None
0a
multi
A i.e. Protein linked with glycosidic bond
Biochemistry
null
7e822c2e-b62b-4f0e-9306-9b5ec1ff9ca7
At what age baby with congenital hypertrophic pyloric stenosis show symptoms
At the time of birth
First week
3rd to 4th week
Second month
2c
single
Baby show the symptoms of projectile vomiting, olive shaped mass and visible peristalsis
Surgery
null
89500db2-ff0d-4895-a9cf-86fb6c58d465
All of the following may be used to treat hypercalcemia, except:
Normal saline with forced diuresis with chlohiazide
Plicamycin
Gallium nitrate
Mitramycin
0a
multi
Answer is A (Normal saline with forced diuresis with Thiazides): Thiazide diuretics should not be used in cases of hypercalcemia as these may themselves cause hypercalcemia.
Medicine
null
f5e78622-1e8a-4e33-a166-676c72d4c3f0
The most commonly practiced operative procedure for a perforated duodenal ulcer is -
Vagotomy and pyloroplasty
Vagotomy and antrectomy
Vagotomy and perforation closure
Graham's omentum patch repair
3d
single
Ans. is 'd' i.e., Graham's omentum patch repair
Surgery
null
d54ab332-7771-48fd-8721-be014089d3fa
Donovan bodies are:
Leukocytes that contain the organism, Calymmatobacterium granulomatis
EosinophiLs that contain the organism, Calymmatobacterium granulomatis
Monocytes that contain the organism, Haemophilus influenza
Monocytes that contain the organism, Calymmatobacterium granulomatis
3d
single
Monocytes that contain the organism, Calymmatobacterium granulomatis
Microbiology
null
60dc935f-82bf-49e1-aa25-58a037bb5f42
Which of the following structures seen in the cavernous sinus?
Maxillary division of V nerve
Mandibular division of V nerve
Internal carotid aery
Trochlear nerve
2c
single
Ans. c. Internal carotid aery
Anatomy
null
71873be2-d2fa-4f70-bb70-f2b08942ecf9
A symptom of medullary sponge kidney disease is -
Nocturia
Anemia
Azotemia
UTI
3d
single
Medullary sponge kidney is a congenital disorder characterized by cystic dilatation of papillary collecting ducts of one or both kidneys. Urinary stasis in the dilated ducts, hypocitraturia, and, occasionally, incomplete distal renal tubular acidosis (dRTA) contribute to the formation of small calcium-containing calcul...
Surgery
null
53b6d52f-ce67-475e-9f14-5731aa6bfb3b
Tardieu spots are a feature of which of the following forms of death?
Cyanide poisoning
Mechanical asphyxia
Cobra bite
Organophosphate poisoning
1b
single
Tardieu spots or petechial haemorrhages are pinhead size bleeding spots occurring as a result of rupture of venules and are most commonly seen in sclera, conjunctiva or on serous membranes. It is seen in case of mechanical asphyxia. Ref: Textbook of Forensic Medicine and Toxicology By V.V Pillay, 15th Edition, Page 275
Forensic Medicine
null
286c7f83-dc51-4a9d-b407-b36c60de36e7
Metastasis in neuroblastoma goes to -
Liver
Lung
Bone
Bone marrow
1b
single
Lung metastasis at initial diagnosis of neuroblastoma is associated with MYCN amplification and elevated LDH levels. Although lung metastasis at diagnosis was not independently predictive of outcome in this analysis, it remains a useful prognostic marker of an unorable outcome.
Pathology
Pediatrics, environment and nutrition
92e72deb-d0bc-485c-81a3-6af699e85c8a
Deposition of protein 'A beta 2m' is seen in which clinicopathologic category of amyloidosis -
Familial Mediterranean fever
Hemodialysis associated
Senile cerebral
Systemic senile
1b
single
Ans. is 'b' i.e., Hemodialysis associated
Pathology
null
94c2904d-2d6d-4d92-9ad9-a88415418efb
Aerial blood gas of a 5 year old child done at sea level gives the following results: pH 7.41, PaO2, 100 mmHg, and PaCO2, 40 mmHg. The child is being ventilated with 80% oxygen. What is the (A-a) DO2.-
570.4 mm Hg
520.4 mm Hg
470.4 mm Hg
420.4 mm Hg
3d
single
Alveolar air equation: Using the alveolar air equation - PAO2 = - Data: Fraction of O2 in the inspired air = 80% Barometric pressure = 760 mm Hg (sea level) Water vapor pressure = 47 mm Hg Respiratory quotient = 0.8 Hence, Alveolar PO2 = - = 570.4 - 50 = 520.4 mm Hg Aerial PO2 is given = 100 mm Hg Hence, (A - a) DO2 = ...
Physiology
Respiratory System Pa 3
85a88804-96b9-42ec-93b8-a13c0b2daaf1
A child presented with a history of unilateral purulent nasal discharge with occasional bloody discharge from the same side, The diagnosis is -
Antrochoanal polyp
Foreign body
Angiofibroma
Rhinosporidiosis
1b
single
Unilateral purulent nasal discharge with occasional bloody discharge in a child is highly suggestive of foreign body. Antrochoanal polyp does not cause bloody discharge. Angiofibroma most commonly presents with nasal obstruction and epistaxis (not purulent nasal discharge). Rhinosporidiosis presents most commonly with ...
ENT
null
278a64a6-fe13-486e-83ab-b3541733296c
DNA fingerprinting was founded by:
Watson
Calton
Jeffrey
All of the above
2c
multi
C i.e. Jeffrey
Medicine
null
948272d8-4118-44e3-becc-6c60a3f8222a
For a class V cavity for amalgam:
Mesio-distal walls are parallel and occluso-gingival walls converging
Mesio-distal walls diverging, occlusogingival walls converging
MD walls diverging, OG walls diverging
MD walls and OG walls parallel
2c
multi
null
Dental
null
a6958436-9471-4225-b5d2-c477192da91d
A patient Shweta with raised serum alkaline phosphatase and raised parathormone level along with low calcium and low phosphate level is likely to have
Primary hyperparathyroidism
Paget's disease
Osteoporosis
Vitamin D deficiency
3d
single
Answer is D (Vitamin D deficiency) Serum Ca Serum phosphorus Alkaline phosphatase PTH * Osteomalacia (Rickets) (|iNit. D) | | | | * Primary hyperparathyroidism bone disease | | , | | * Bone disease in renal failure with secondary hyperparathyroidism N/| | | | * Lytic bone neoplasms N/| N/| N/| N * Osteoporosis N N N N ...
Medicine
null
24bfc067-fe79-4696-89ae-f92efce9d84e
During the Window period of patient with AIDS -
ELISA is -ve
Western Blot is -ve
Both are -ve
PCR is -ve
2c
multi
sero negative infective stage is known as the window period REF:ANANTHANARAYANAN TEXT BOOK OF MICROBIOLOGY 9EDITION PGNO.579
Microbiology
Virology
851f0325-df1c-4498-80e3-4a5d276396a4
In Bismuth/ Strasberg classification system cystic blow out is classified as:
Type A
Type B
Type C
Type D
0a
single
null
Surgery
null
9988d555-e41d-4f02-b78f-60f6b6f93b66
If circumflex aery gives the posterior interventricular branch, this circulation is described as
Right dominance
Left dominance
Codominance
Undetermined
1b
single
In about 10% of heas,the right coronary is rather small and is not able to give the posterior interventricular branch. In these cases the circumflex aery,the continuation of left provides the posterior interventricular branch and called left dominant. <img src=" /> B D CHAURASIA'S HUMAN ANATOMY UPPER LIMB THORAX-VOLUME...
Anatomy
Thorax
9fe50a93-278b-41d1-898d-a31b95709b08
Parvovirus B19 does not cause
Roseola infantum
Aplastic anemia in sickle cell disease
Fetal hydrops
erythema infectiosum
0a
single
parvovirusB19 causesaplasyic crisi ,persistent anemia,erythema infectiosum&fetal hydrops REF:ANATHANARAYANAN MICROBIOLOGY NINTH EDITION PAGE.554
Microbiology
Virology
6220ae04-06a1-47bf-81cc-b325989a0074
Marker of acute kidney injury all except?
Clusterin
Osteopontin
Alanine aminopeptidase
Acid phosphatase
3d
multi
Ans. is 'd' i.e., Acid phosphatase o Acid phosphatase is not a market of AKI, instead it is alkaline phosphatase.o List of markers for AKI# Alanine aminopeptidase(AAP)# Alkaline phosphatase (AP)# a-GIutathione-S-transferase (a-GST)# g-Glutamyl transpeptidase (gGT)# N-Acetyl-b-(D) gluco-saminidase (NAG)# b2-Microglubuli...
Medicine
Acute Renal Failure
1a9dc641-10a9-4571-90d1-9483cb14029e
Button hole sign is seen in:
Lupus vulgaris
Intertigo
Neuro fibromatosis
Psoriasis
2c
single
Due to defect in dermis, pressure on a neurofibroma gives a feeling of hole in dermis, which is called as Button hole sign.
Dental
null
108ab257-4a62-4cb6-804b-a8fb57aedf1a
Lipoxins synthesized from arachidonic acid act by-
Decrease leucocyte migration, adhesion, chemotaxis
Increase leucocyte migration, adhesion, chemotaxis
Vasoconstriction
Increased vascular permeability
0a
single
lopoxins are the metabolites produced lipooxygenase pathway. They act to regulate and counter Balance actions ad Leucotriens i:e, decreases leukocyte adhesion, migration and chemotaxis. .ref Robbins 9/e p46
Pathology
General pathology
611702fc-bc99-44cf-a9bb-69e365205fbb
Active management of 3rd stage of labour is needed for all the following EXCEPT
Rh incompatibility
Diabetic mother
Prolonged pregnancy
Delivery of first baby of twins
3d
multi
Ans. d (Delivery of first baby of twins) (Ref. Textbook of Obstetrics D.C. Dutta 6th/pg. 142)Accidental administration of ergometrine or methergin during delivery of first baby in undiagnosed twins produce grave danger to the unborn 2nd baby caused by asphyxia due to tetanic uterine contractions.MANAGEMENT OF THE THIRD...
Gynaecology & Obstetrics
Miscellaneous (Gynae)
9f6df3d9-afba-4deb-a685-78f648de5caf
Which is a DNA virus ?
Hepatitis A
Hepatitis B
Hepatitis C
Hepatitis D
1b
single
Ans. is 'b' i.e., Hepatitis B
Microbiology
null
d17e8812-8507-4726-b1f8-d82be8a09a9b
Which of the following glycolytic enzyme is used in gluconeogenesis?
Glucokinase
Pyruvate kinase
Aldolase
Phosphofructokinase
2c
single
Aldolase is the enzyme which catalyzes the reversible reaction of glycolysis. So this enzyme is utilized in gluconeogenesis.Glucokinase, pyruvate kinase and phosphofructokinase are enzymes which catalyze the irreversible reaction of glycolysis and which are bypassed by different sets of enzymes during gluconeogenesis.
Microbiology
All India exam
390ec4b8-dd44-4cdd-8065-609d9fc943d9
In pneumothorax due to blunt injury, treatment of choice is -
Observation
Pneumonectomy
Thoracotomy
Intercostal drainage
3d
single
null
Surgery
null
29c07a2a-41e2-4929-a4af-b18191223ff9
A 53-year-old female nonsmoker is being evaluated with symptoms of progressive shoness of breath. She has a past history of trauma to the right side of the chest. There is no history of asthma, sputum production, or recent chest pain. CXR is shown in,The likely diagnosis is
Calcified cyst
Organized hemothorax
Blastomycosis
Asbestosis
1b
single
There is a large, well-demarcated, calcified pleural-based opacity abutting the lateral chest occupying two-thirds of the left hemithorax. It has a rounded, intensely calcified inferior and medial border and thus suggests a pleural origin. The shadow is most consistent with a large, old organized hemothorax. The calcif...
Radiology
Respiratory system
9ddb4c7b-5115-4349-80c4-a973b09a0771
Predisposing factors for endometrial carcinoma is :
Hypeension
Late menopause
Nulliparity and Diabetes mellitus both
All
3d
multi
All
Gynaecology & Obstetrics
null
7570ad1b-7a71-4a46-a6d7-0125cbc2a61a
Which of the following connective tissue disorder is associated with gastroesophageal reflux?
SLE
Scleroderma
Behcet's syndrome
Dermatomyositis
1b
single
Scleroderma is systemic disease accompanied by esophageal abnormalities in approximately 80% of patients. The esophageal lesion consists of atrophy of the smooth muscles, manifested by weakness in the lower two-third of the esophageal body and incompetence of the LES. Gastroesophageal reflux is due to incompetent LES c...
Surgery
null
2f7b1086-cd8d-411b-a2e4-811532e8fbcb
Subdural Hematoma (SDH) is caused by
Bridging veins
Caroticocavemous fistula rupture
Middle meningeal artery
None
0a
multi
(A) Bridging veins # SUBDURAL BLEEDING arises from rupture of cortical vessels/bridging veins.> Relatively severe trauma> No lucid interval> Diffuse concave lesion on computed tomography> Require immediate transfer to a neurosurgical unit for decision on evacuation 50 per cent mortality.
Surgery
Miscellaneous
5487bd71-7f0e-4d50-91a6-9e486d860c72
Thiazide diuretic used when GFR<30 ml/min?
Metolazone
Benzthiazidc
Chlohiazide
Hydrofulthiazide
0a
single
Ans. is 'a' i.e., Metolazone o Metolazone is the only thiazide which is effective in severe renal failure.
Pharmacology
null
9c5a488d-97f1-4e77-b4d3-d21cb0f0c9f6
Which of the following traditional medicines is effective in the treatment of hea failure
Terminalia Arjuna
Neem bark extract
St. John's wo
Gingkoba biloba
0a
single
Ans. a. Terminalia Arjuna Terminalia Arjuna (An ayurvedic cardioprotective botanical) Although many Ayurvedic plants have shown to help coronary aery disease, Arjuna (Terminalia Arjuna) by far seems to be the best plant for hea health. Terminalia arjuna is a traditional ayurvedic plant containing tannins, triterpenoid ...
Pharmacology
null
95f22481-cf82-4c1f-bac4-be74a2e1997f
Selenocysteine is derivative of which aminoacid -
Serine
Alanine
Arginine
Glycine
0a
single
Ans. is 'a' i.e., Serine o Selenocysteine is considered as 21" standard amino acid. o It is present at the active site of some enzymes that catalyze redox reactions, e.g. thioredoxin reductase, glutathione peroxidase, and the deiodinase (converts thyroxin to triiothyronine). o Biosynthesis of selenocysteine requires cy...
Biochemistry
Amino Acids Basics
b010c4fd-35c5-440f-a8aa-8219c856ae18
Which of the following local anaesthetic is NOT used as a surface anaesthetic?
Lignocaine
Tetracaine
Cocaine
Bupivacaine
3d
single
Bupivacaine is a widely used amide local anesthetic. It is a potent agent capable of producing prolonged anesthesia. Its long duration of action plus its tendency to provide more sensory than motor block has made it a popular drug for providing prolonged analgesia during labor or the postoperative period. By taking adv...
Anaesthesia
null
f717c467-4c26-4e62-9e7a-fdfd8007986f
Undescended testis can lead to all of the following complications except: March 2012
Torsion
Sterility
Carcinoma
Hyperophy of testes
3d
multi
Ans: D i.e. Hyperophy of testes Complications of undescended testes Torsion can be seen in incomplete testicular descent Sterility is seen in bilateral cases (especially intra-abdominal testes) Incomplete testicular descent predisposes to malignant disease; cancer is more common in an incompletely descended testes-orch...
Surgery
null
45d980dc-0b54-4db0-b556-6df36cbc1534
Keratoderma Blenorrhagica is typically seen in
Rheumatoid ahritis
Psoriatic Ahritis
Reactive Ahritis
Ankylosing spondylitis
2c
multi
Ans. is 'c' i.e., Reactive ahritis Keratoderma Blenorrhagica is the characteristic skin lesion seen in patients with Reactive Ahritis. "The Characteristic skin lesions in Reactive Ahritis, Keratoderma Blenorrhagica, consist ofvesicles that become hyperkeratotic, ultimately forming a crust before disappearing. These are...
Medicine
null
4fccd3d5-4706-4f62-8708-46c2d05b5faf
Initial amino acid in prokaryotic protein synthesis -
Arginine
Methionine
Formyl-methionine
Alanine
2c
single
Ans. is 'c- i.e., Formyl-methionine o in prokaryotes and in mitochondria, the first amino acid methionine is modified by formylation, i.e. the initiator t-RNA carries an N-formylated methionine. The formyl group is added by the enzyme transformylase (formyl- transferase). In Eukaryotes, the initiator t-RNA carries a me...
Biochemistry
Amino Acids Basics
6bbd139e-6000-4acb-beb0-042dc471df1e
Antiglaucoma drug which acts by increasing uveo- sclerol outflow -
Apraclonidine
Latanoprost
Timolol
Brinzolamide
1b
single
Ans. is 'b' i.e., Latanoprost Drugs used in open-angle glaucoma MechanismMethods of AdministrationCholinomimetics Pilocarpine, carbachol, physostigmine, echothiophate, demecariumCiliary muscle contraction, opening of trabecular meshwork, increased outflowTopical drops of gel; plastic film slow-release insertAlpha agoni...
Pharmacology
Anti Adrenergic System
f8000fa0-b8f6-47d3-9503-f2cd30e935f9
Most commonly affected organ in the disorder characterized by the peripheral blood smear is:
Lungs
Kidney
Spleen
Liver
2c
single
Hereditary Spherocytosis—Peripheral blood smear.   Splenomegaly is more common and prominent in hereditary spherocytosis than in any other form of hemolytic anemia. The splenic weight usually is between 500 and 1000 g. The enlargement results from marked congestion of the splenic cords and increases in the numbers of m...
Pathology
null
6a48c652-ecd2-40d4-b57b-074bf293d393
Boiled cabbage or rancid butter smelling urine is seen in
Phenylketonuria
Tyrosinemia
Isovaleric Acidaemia
Multiple carboxylase deficiency
1b
single
Tyrosinemia REF: Sapira's a & science of bedside diagnosis - Page 138, Textbook of Pediatric Emergency Medicine by Gary R. Fleisher, Stephen Ludwig Page 1566 Tyrosinaemia is an error of metabolism, inherited, in which the body cannot effectively break down the amino acid tyrosine, found in most animal and plant protein...
Biochemistry
null
26a9c0a6-cf97-40dc-bac8-b30db91d1860
All are side effects of clozapine expect:
Granulocytopenia
Seizures
Sedation
Extrapyramidal side effects
3d
multi
Ref: KDT 8th ed Clozapine is an atypical antipsychotic drug. It does not block D2 receptors, therefore chances of extrapyramidal symptoms are least with this drug.
Pharmacology
Central Nervous system
c1d9a954-ed52-4723-973a-355d3be579ae
All of the following are true about staing betablocker therapy in cases of CHF, Except
They should be initiated at the effective doses
They should be gradually increased over weeks
Special precautions should be taken in NYHA class III & IV
Carvedilol and Metoprolol are the preferred drugs
0a
multi
Answer is A (They should be initiated at the effective doses) Beta blocker should be initiated at lower than effective doses in CHF Beta blockers should be initiated at lower than effective doses in CHF and be 'Beta blockers should be initiated at low doses followed by gradual increments in the dose if lower doses have...
Medicine
null
bbdd80b6-d9db-484a-b348-612f8131340e
A patient with a peptic ulcer was admitted to the hospital and a gastric biopsy was performed. The tissue was cultured on chocolate agar incubated in a microaerophilic environment at 37degC for 5 to 7 days. At 5 days of incubation, colonies appeared on the plate and were curved, Gram negative rods, oxidase positive. Th...
Campylobacter jejuni
Vibrio parahaemolyticus
Haemophilus influenzae
Helicobacter pylori
3d
single
This organism is readily isolated from gastric biopsies but not from stomach contents. It is like Campylobacter species and grows on chocolate agar at 37degC in the same microaerophilic environment suitable for C. jejuni (Campy-Pak or anaerobic jar without the catalyst). H. pylori, however, grows more slowly than C. je...
Microbiology
Systemic Bacteriology (Haemophilus, Yersinia, Spirochaetes, Ricketssia, Chlamydia, Mycoplasma and Miscellaneous Bacteria)
0de12fbd-c9de-4106-b321-27db49459f1e
In CML serum vitamin B12 level is:
Slightly decreased
Normal
Markedly decreased
Increased
3d
single
Wintrobes hematology mentiins granulocytes contain and release B12 binding proteins.Markedly elevated transcobalamin 1 level are seen in chronic myelocytic leukemia and myeloid metaplasia whereas low levels are seen in chronic leucopenia and aplastic anemia. Williams hematology 8th adds that the increase is propoional ...
Anatomy
Haematology
b6967054-beb5-4661-a64d-40cb11cd2b4d
A 52-year-old businessman with nephrotic syndrome after a non-stop flight from New York to New Delhi presents with sudden onset of breathlessness, haemoptysis, and chest pain. He is brought into Casualty in shock. His chest X-ray is normal. The ECG shows sinus tachycardia.
Pneumothorax
Myocardial infarction
Pulmonary embolism
Aoic dissection
2c
single
1. In this patient no pulmonary edema, MI absent and aoic dissection also absent. 2. Nephrotic syndrome patient will be in hypercoagulable state, long flight- DVT- pulmonary embolism- acute Cor pulmonale 3. Most common causes of Cor pulmonale- pulmonary embolism 4. CXR is normal because it is only a small clot and clot...
Medicine
Thromboembolism and Fat Embolism Syndrome
335dafcd-9a46-42c8-a359-e59cb1b94af7
A farmer has an ulcer on leg with indurated margin and multiple sinuses with discharging granules. The likely diagnosis is -
Mycetoma
Scrofuloderma
Lupus vulgaris
Actinomycosis
0a
single
Ans. is 'a' i.e., Mycetoma Mycetoma (Maduramycosis) . Is a localized chronic granulomatous involvement of the subcutaneous and deeper tissues, commonly affecting the foot and less often the hand and other pas. . Presenting as a subcutaneous swelling with multiple discharging sinuses. . Sinuses discharge seropurulent fl...
Microbiology
null
28f2d995-58df-4b65-8b72-5363141151c9
Spaghetti and meatball appearance is seen in
Dermatophytes
Aspergillus
Pityriasis versicolor
Candida
2c
multi
In pityriasis versicolor while doing  KOH mount shows a mixture of short , branched hyphae and spores described as spaghetti and meatballs appearance.
Dental
null
f09ed125-f426-4aa4-9cd1-0ca304cf0787
Drug which is useful in neuronal diabetes inspidus in both children and adults given intra nasally -
Vasopressin
Desmopressin
Lypressin
Presselin
1b
multi
Ans. is 'b' i.e., Desmopressin Desmopressin (intranasal) is the DOC for central DI.
Pharmacology
null
ea2f8f25-318b-49d3-9cfa-cf8e661a5eeb
Magnan syndrome is seen in which poisoning-
Morphine
Alcohol
Cannabis
Cocaine
3d
single
Ans. is 'd' i.e., Cocaine
Forensic Medicine
null
81e75f78-2c14-4b8d-bcff-1f3d47cdc9ed
The denominator in General feility rate
Live bihs
Mid year population
Reproductive women in the age group 15-45 mid year population
Married women in the age group 15-45
2c
single
General feility rate (GFR) : Number of live bihs per 1000 women in the reproductive age group 15-49 years in a given year Denominator : Takes 'mid-year population' of 15-49 years age females into account Ref: Park 25th edition Pgno : 539
Social & Preventive Medicine
Non communicable diseases