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135
63a1ddb2-89d9-48c7-8f32-7f854236810e
A child presents with recurrent respiratory tract infection, mouth breathing and decreased hearing. Treatment is:
Tonsillectomy
Adenoidectomy
Grommet inseion
All
3d
multi
Child is presenting with mouth breathing. Palate is high arched.There is nasal obstruction and recurrent respiratory tract infections along with hearing impairment. All these features are suggestive of adenoid hyperplasia. In case of adenoid hyperplasia, impairment of hearing is due to secretory otitis. Thus the logica...
ENT
null
9c7daf15-4f32-4c88-90d7-8b7f9d9dc239
All are major cytokines in chronic inflammation except
IL-6
IL-12
IFN-y
IL-17
0a
multi
Ans. (a) IL-6(Ref: Fundamental immunology by William E Paubl 1030, Koj -chapter 3; Refer to Ans 69)Il6 IS INVOLVED IN ACUTE FRBRILE RESPONSES Others are involved in chronic inflammation
Pathology
Inflammation & Repair
13877362-5a67-44b4-ba53-533d503f66e7
Olopatadine is:
Mast cell stabilizer
Anti-histamine
Both mast cell stabilizer and anti histamine
None of the above
2c
multi
Ref: Clinical Oculor Pharmacology, 1st ed. pg. 257* Olopatadine hydrochloride is an antihistamine (as well as anticholinergic and mast cell stabilizer)* It is used as eye drop to treat itching associated with allergic conjunctivitis.* Side effects include headache, eye burning and/or stinging, blurred vision, dry eyes,...
Pharmacology
Endocrinology
96e52b4c-8fbe-4a68-8437-b9778108cf6b
Ketone body formation takes place in:
Liver
Kidney
Spleen
Blood
0a
single
A Harper, 26th ed, p. 183 & 25th ed, p. 243, Fig (24.6)
Biochemistry
Lipids
592fea53-9a72-43d5-ba1b-9b3dcfdff066
Purposeful movement is staed at
6 months
8 months
9 months
12 months
0a
single
Palmer grasp goes at age of 4 monthTransfer object hand to hand 5.5 monthThe purposeful movement staed when there is an absence of Palmer group, so an above option best answer is 6 month(Refer: Nelson's Textbook of Pediatrics, SAE, 1st edition, pg no. 2798)
Pediatrics
All India exam
d2e66250-f2fd-4151-88f3-c4c5b4909a6b
Which of the following structures form the superior border of Epiploic foramen ?
Quadrate lobe of liver
Caudate process of caudate lobe of liver
Poa hepatis
First pa of the duodenum
1b
single
In human anatomy, the omental foramen (Epiploic foramen, foramen of Winslow, or uncommonly aditus) is the passage of communication or foramen, between the greater sac (general cavity of the abdomen) and the lesser sac.Borders of Epiploic foramen: It has the following boundaries:Anteriorly : free border of lesser omentu...
Anatomy
null
e699b00a-fddc-40d6-ba00-cf9960fcc4a4
Antidote for organophosphorus poisoning is -
PAM
Adrenaline
Anti-dopaminergics
Ephedrine
0a
single
Antidotes for OP compounds : (1) atropine (2) oximes (Pralidoxime : PAM, obidoxime and diacetylmonoxirne : DAM).
Forensic Medicine
null
acac1b45-5029-42a8-ba47-be22e8f3bee0
EBV is associated with which type of cancer?
Nasopharyngeal carcinoma
Epidermodysplasia
Kaposi sarcoma
None
0a
multi
Epstein-barr virus may lead to the following clinical conditions:* Infectious mononucleosis* Epstein-barr virus associated malignancies: - Burkitt's lymphoma - Lymphomas in immunodeficient person such as those with AIDS and transplant recipients - Nasopharyngeal carcinoma in persons of Chinese origin.
Microbiology
DNB 2018
3a22eaa4-bb78-43cb-8aa0-7bca8d751dce
Hyperaldosteronism is associated with all, EXCEPT:
Hypernatremia
Hypokalemia
Hypeension
Metabolic acidosis
3d
multi
Primary hyperaldosteronism causes extracellular volume expansion and hypeension by increasing distal sodium reabsorption. Aldosterone increases H+ and K+ excretion, producing metabolic alkalosis and hypokalemia. Therapy for saline-unresponsive metabolic alkalosis includes surgical removal of a mineralocoicoid-producing...
Physiology
null
7e8660fb-1d21-4320-a2b8-9760cff656b3
A 28-year-old patient has multiple grouped papulovesicular lesions on both elbows, knees buttocks and upper back associated with severe itching. The most likely diagnosis is –
Pemphigus vulgaris
Bullous pemphigoid
Dermatitis herpetiformis
Herpes Zoster
2c
multi
Look for itching → Severe itching Papulovesicular lesion On extensors (knees, elbows), scapular region (upper back), buttock. Age → 28 years
Dental
null
c32f8547-3512-4256-8030-868502c130e9
Tongue muscle which is not developed from occipital myotome ?
Styloglossus
Hyoglossus
Genioglossus
Palatoglossus
3d
single
DEVELOPMENT OF THE TONGUE :? I. Epithelium a) Ant 2/3 -- lingual swellings of 1st arch and tuberculum impar b) Post 1/3 -- large dorsal pa of hypobranchial eminence, Le. 3rd arch c) Posterior most pa -- small dorsal pa of the hypobranchial eminence, i.e. 4th arch II. Muscles From occipital myotomes except palatoglossus...
Anatomy
null
51351c00-e363-419e-9052-23ca53fc9362
Sodomy is punishable under:NEET 14
Sec. 354 IPC
Sec. 375 IPC
Sec. 377 IPC
Sec. 378 IPC
2c
single
Ans. Sec. 377 IPC
Psychiatry
null
3bcf18e2-7da2-4c1b-80ba-38a17aca8644
The drug of choice for the treatment of Thyrotoxicosis during pregnancy is
Carbimazole
Iodine therapy
Propyl Thiouracil
Metimazole
2c
single
(C) Propyl Thiouracil # All antithyroid drugs can cross placenta so risk of fetal hypothyroidism and goitre is always there.> Both carbimazole and propylthiourcil can be used during pregnancy, but propyl-thiouracil is the drug of choice because its greater protein binding allows low doses of propylthioracil to be trans...
Medicine
Miscellaneous
fdb3db95-78f0-4579-842d-4c8c9445e57d
Drugs are used in AKT-4 kit for TB as
None
Decrease in resistance by conjugation
To cure disease early
Decrease in resistance by mutation
3d
multi
null
Social & Preventive Medicine
null
48bf4552-3a7b-4b08-b521-6d2a92697e9a
A 47-year-old man is found to have edema, ascites, and hepatosplenomegaly. The examination of his neck veins reveals elevated venous pressure with a deep y descent. Heart size on x-ray is normal. Which of the following etiologies is not a possible explanation for this syndrome?
rheumatic fever
TB
unknown cause
previous acute pericarditis
0a
single
Commonly, no cause is found for constrictive pericarditis. Some patients do give a history of previous acute pericarditis. TB is now an uncommon cause. Cancer can cause constriction but is uncommon. Rheumatic fever does not cause pericarditis.
Medicine
C.V.S.
11a218be-6cac-4265-b84c-5658735c4fff
In sickle cell anaemia defect is in which chain ?
a-chain
B-chain
Both the chains
None of these
1b
multi
Ans. is 'b' i.e., n-chain
Pathology
null
7bf77e57-99bb-4774-910d-3f16127586d1
Waddling gait due to: March 2009
Bilateral congenital dysplasia of hip
Coxa valga
CTEV
Bilateral coxa valgum
0a
single
Ans. A: Bilateral congenital dysplasia of hip A waddling gait is the style of walking that is seen in a patient with proximal myopathy. It is characterised by: A broad-based gait with a duck-like waddle to the swing phase The pelvis drops to the side of the leg being raised Forward curvature of the lumbar spine Marked ...
Surgery
null
3bdf8cc4-529c-4236-b9ef-771fbc7d45bb
Treatment of Advanced Proliferative Diabetic Retinopathy with extensive vitreoretinal fibrosis and fractional retinal detachment involves all of the following, EXCEPT:
Reattachment of detached or torn retina
Removal of epiretinal membrane
Vitrectomy
Exophotocoagulation
3d
multi
There is no role of Exophotocoagulation in the management of advanced proliferative diabetic retinopathy with complications such as fractional RD and extensive vitreoretinal fibrosis. Endophotocoagulation may be used in conjunction with vitrectomy. Ref: Oxford Textbook of Medicine 4th /350; Current Geriatric Diagnosis ...
Ophthalmology
null
c7e86382-a87f-4f75-affc-d8b4821170d4
All of the following are H2 blockers except ?
Cimetidine
Ranitidine
Famotidine
Omeprazole
3d
multi
Ans. is `d' i.e., Omeprazole Drugs for peptic ulcer 1. Reduce gastric acid secretion a) H2 antihistaminic - Cimetidine, Ranitidine, Famotidine, Roxatidine. b) Proton pump inhibitors - Omeprazole, Lansoprazole, Pantoprazole, Rabeprazole, Esomeprazole. c) Anticholinergics - Pirenzepine, propantheline, oxyphenonium. d) Pr...
Pharmacology
null
fb980300-ff4b-41b3-b680-9436b1b3ca8c
X-rays are a type of
Atomic radiation
Ultrasonic radiation
Electromagnetic radiation
Particulate radiation
2c
single
null
Radiology
null
2889e536-9889-48df-aff7-f1458f6c90e2
Activation of which receptor causes pulmonary vasoconstriction?
Alpha 2 adrenergic
H2 histamine
M3 cholinergic
ETA epithelial receptor
3d
single
Activation of ETA receptor causes pulmonary vasoconstriction. These are endothelin receptors.Ref: Ganong review of medical physiology, 23rd edition Page no: 609
Physiology
Respiratory system
382dd98d-650d-40ee-82a2-bfa73949ce88
Shock lung synonym is used for
COPD
Alveolar proteinosis
ARDS
HMD
2c
single
Ans. C. ARDSShock Lung/ARDS is a clinical syndrome caused by diffuse alveolar capillary and epithelial damage. There is usually rapid onset of life-threatening respiratory insufficiency, cyanosis, and severe arterial hypoxemia that is refractory to oxygen therapy and that may progress to multisystem organ failure. The ...
Medicine
Respiratory
c7c5ffa7-c62c-443b-a588-ca092d0debde
The commonest cause of Enuresis in children is -
Urinary tract infection
Spina bifida
Psychologic stress
None
3d
multi
Ans. is None o Genetic factors are the most common etiology for enuresis. Nelson o Beyond genetic factors, the cause of enuresis likely involves a complex web of physiologic and perhaps psychologic factors.
Pediatrics
null
be02c8e1-11d2-4bd7-88ea-3f0b8c3521a4
Trans-tubular potassium gradient (T.T.K.G) in hypokalemia is?
<3-4
>6-7
>9-10
>10-15
0a
single
The expected values of the Trans-tubular potassium gradient (T.T.K.G) are <3-4 in the presence of hypokalemia and >6-7 in the presence of hyperkalemia. TTKG is measured as follows:
Medicine
Fluids and Electrolyte Imbalance
7eab82f9-8f1c-4522-8744-570c6cec3c7b
Which of the following investigation would be diagnostic of cystic fibrosis?
Deficiency of the enzyme mucinase
High sweat chloride content
Alpha-1 aldolase deficiency
Increased copper excretion in urine
1b
single
A sweat test measures the amount of chloride, a pa of salt, in Sweat. It is used to diagnose cystic fibrosis (CF). People with CF have a high level of chloride in their sweat. CF is a disease that causes mucus build-up in the lungs and other organs. It damages the lungs and makes it hard to breathe Ref Davidson 23rd ed...
Medicine
Miscellaneous
e4354f2c-cd8d-4a2b-ab56-11a37ccd2542
Intention tremor is characteristic of :-
Parkinson’s disease
Fronto temporal Dementia
Progressive Supra Nuclear Palsy
Cerebellar lesions
3d
single
Intention tremor is seen in cerebellar lesions and “pill-rolling” tremors at rest is typical of Parkinson’s disease.
Medicine
null
79bc1dd0-acfc-4313-8c05-78bce8bd7f03
Site of lesion in Bitemporal hemianopia is ?
Optic nerve
Optic tract
Optic chiasma
Optic radiation
2c
single
Ans. is 'c' i.e., Optic chiasma Characteristic defect of central chiasmatic lesion is bitemporal hemianopia. This question has been asked in almost all the examinations. Site oflesion Visual field defect Optic nerveOptic chiasmaOptic tractLateral geniculate bodYOptic radiation (Total)Optic radiation lower fibres (tempo...
Anaesthesia
null
1158ac2d-9b6c-4a2c-bbcd-127f869f1238
Patient of Rectovaginal fistula should be initially treated with
Colostomy
Primary repair
Colporrhaphy
Anterior resection
0a
multi
Recto-Vaginal Fistula Management Preliminary colostomy is done Local repair after 3 weeks Closure of colostomy after 3weeks Ref: D.C.DUTTA&;S TEXTBOOK OF GYNAECOLOGY; 6th edition; Pg no:428
Gynaecology & Obstetrics
Urogynecology
69beeaad-ca09-4c1e-b28e-0a66156d64b7
Turban epiglottis is seen in
Tuberculosis
Leprosy
Laryngeal papilloma
Epiglottitis
0a
single
Turban epiglottis is due to oedema and infiltration of the epiglottis and is caused by laryngeal tuberculosis. Lupus: a form of tuberculosis, on the other hand, eats away and destroys the epiglottis. Pseudoedema of the epiglottis is known as "turban epiglottis". Ref: PL Dhingra 7th edition of Ear, Nose and Throat; Pg n...
ENT
Larynx
ee002345-22c8-41d4-a42c-559705962a20
Arthritis mutilans is due to:
Psoriatic arthritis
Osteoarthritis
Rheumatoid arthritis
Rheumatic arthritis
0a
single
Ans: a (Psoriatic arthritis) Ref: Harrison's, 16th ed,p. 1998; 17th ed, p. 2115Arthritis mutilans is due to psoriatic arthritis. Psoriatic arthritis involves PIP, DIP and metacarpopha- langeal joints and may or may not involve the wrist.Psoriatic arthritis can present with a wide spectrum of clinical features namely:1)...
Medicine
Immunology and Rheumatology
af5d8acd-c032-48a6-8c88-86fa51b49381
NOT a complication of massive blood transfusion: March 2013 (d)
Septicemia
Thrombocytopenia
Hypehermia
ARDS
2c
single
Ans. C i.e. Hypehermia Hypothermia is seen and hence blood should be warmed before infusion
Anaesthesia
null
7ad10ce8-f679-47fd-8fd7-69dd293ccc27
A 50-year-old male presented with signs and symptoms of restrictive hea disease. A right ventricular endomyocardial biopsy revealed deposition of extracellular eosinophilic hyaline material. On transmission electron microscopy, this material is most likely to reveal the presence of
Non branching filaments of 7.5 to 10 nm
Cross banded fibres with 67 m periodicity
Weber Palade bodies
Concentric whorls of lamellar structures
0a
single
Amyloidosis is the major cause of restrictive cardiomyopathyCardiac amyloid is classically suspected from thickened ventricular walls with an ECG that shows low voltage.By electron microscopy, all types of amyloid consist of continuous, nonbranching fibrils with a diameter of approximately 7.5 to 10 nm. X-ray crystallo...
Pathology
miscellaneous
e7d116c0-133f-474a-8aab-23dcfcc16ad7
Which of the following is a disinfectant, sterilizing agent and an antiseptic?
Sodium hypochlorite
Glutaraldehyde
Hydrogen peroxide
Methylated spirit
0a
single
null
Dental
null
6c70b09c-5d5d-4a9b-9037-64983280ab89
Prevalence of vitamin-A deficiency in a community is assessed as the following:
Night blindness-10%
Corneal ulcer-0.1%
Bitot spots-0.5%
Decreased serum retinol level-0.05%
2c
single
Prevalence criteria for determining the xerophthalmia problem: Criteria Prevalence in population at risk (6 months to 6 years) Nightblindness More than 1% Bitot's spots More than 0.5% Corneal xerosis/corneal ulceration/ keratomalacia More than 0.01% Corneal ulcer More than 0.05% Serum retinol (less than 10 mcg/dl) More...
Social & Preventive Medicine
null
a4f8e175-5dce-49d7-a934-deb5e1e65d66
In the Post-disaster phase, all of the following vaccines are mandatory for doctors except:-
Cholera
Typhoid
Measles
Tetanus
2c
multi
Vaccines C/I for population:- Cholera Typhoid Tetanus Other vaccines are relatively CI Vaccines mandatory for Doctors/health providers:- Cholera Typhoid Tetanus
Social & Preventive Medicine
Vaccines
9d0b06e8-5c5f-4de0-a86f-35d49cdc43db
Bence Jones proteinuria is found on a urinalysis specimen from a 63 year old woman. She is developing chronic renal failure and has a high serum urea nitrogen and creatinine. A radiograph of the veebral column demonstrates multiple 1 to 2 cm rounded areas of decreased bone density. The pathological examination from a r...
Pneumocystis carinii pneumonia
Sclerodactyly
Chronic myelogenous leukemia
Amyloidosis
3d
single
Multiple myeloma is one of the most common causes for amyloidosis that leads to renal failure. The plasma cells secrete light chains and produce the proteinuria as well as the amyloid.
Surgery
null
613a5e42-ac53-4b5c-9b52-51ed9b2938ef
True statements regarding vancomycin uses are all of the following except: September 2009
Surgical prophylaxis in MRSA prevalent areas
Drug of choice for pseudomembranous enterocolitis
Effective in penicillin-resistant pneumococcal infection
Methicillin-resistant Staphylococcus aureus infection
1b
multi
Ans. B: Drug of choice for pseudomembranous enterocolitis Vancomycin is used in Proven methicillin-resistant (MR) Staph. aureus (S.A.) or coagulase-negative Staphylococcal infections Serious infections where coagulase-negative Staphylococci is highly suspected (e.g., central line, prosthesis, sternotomy, etc). Endocard...
Pharmacology
null
2453a113-427e-4910-8606-7c7b8e1d05a2
All are true about scleritis except?
painless condition
glaucoma may occur
necrotising scleritis is more severe and destructive form
Anterior scleritis pain worsens at night
0a
multi
null
Ophthalmology
Sclera
ce1d98be-17da-4361-b90f-897af1e29b48
After a single episode of painless gross hematuria in a boy. Doctor performed an excretory urogram showing a filling defect towards the lower renal infundibulum 1.5 cm. in size. What will be the next investigation to be done ?
Cystoscopy
Urine cytology
USG
Retrograde pyelography
2c
single
Ans. is 'c' ie USG There can be various reason for a filling defect on IVP - stones, mass, cyst etc. They can be very well be diagnosed by USG.
Surgery
null
18e5d2f4-6c4d-47d6-850e-caef4182f484
A 60-year-old female presents with epigastric pain, nausea and vomiting, hea rate of 50, and pronounced first-degree AV block on ER cardiac monitor. Blood pressure is 130/80. The coronary aery most likely to be involved in this process is the
Right coronary
Left main
Left anterior descending
Left anterior descending
0a
single
(Fuster, 10/e, pp 52, 88.) The right coronary aery supplies most of the inferior myocardium and supplies the AV node in over 70% of patients. Thus occlusion of this aery can cause ischemia of the AV node with AV block or bradycardia, as well as symptoms of an inferior MI as seen in this patient. AV block can occur with...
Surgery
null
b399ea05-7a91-4542-af24-86c3d8140171
All are true except?
Penetration - Uncoating - Macromolecular synthesis Transcription, Protein synthesis, Replication - Assembly - Release by budding and lysis.
DNA viruses: Adenovirus, Human papilloma virus, Parvovirus B-19, BK and LC polyomavirus, Polio virus.
Gancyclovir: CMV: act on viral DNA.
Viruses causing congenital and neonatal disease: HSV-2, Echovirus, CMV, Parvovirus B19, VZV, HIV, Hepatitis virus.
1b
multi
Ans. B. DNA viruses: Adenovirus, Human papilloma virus, Parvovirus B-19, BK and LC polyomavirus, Polio virus.1. DNA viruses* Parvo viridae (ss DNA) (NE)* Adeno viridae (NE)* Papovaviridae (NE)* Hepadnaviridae (E)* Herpes viridae (E) (1-8)* Pox viridae (E)2. RNA Viruses* Picornaviridae* Rhabdoviridae* Orthomyxoviridae* ...
Microbiology
Virology
846495f6-24e8-49eb-8bae-ef1ab1371a94
WHO Rose Questionnaire is used for -
Alcohol Addiction
Angina Assessment
DVT Assessment
Arrhythmia Assessment
1b
single
Ans. is 'b' i.e., Angina AssessmentThe London school of Hygjne chest pain questionnaire-The Rose questionaire (version for self administration)PARTAa)Have you ever had any pain or discomfort in your chest# Yes# Nob) Do you get this pain or discomfort when you walk uphill or hurry?# Yes# Noc) Do you get it when you walk...
Medicine
Alcohol
4c93dd91-7915-46c6-89f8-c39152569eef
Most common mechanism of transfer resistance in Staphylococcus aureus is:
Conjugation
Transduction
Transformation
Mutation
1b
single
Ans.is. b i.e.' Transduction
Microbiology
null
db4856a6-21f8-4e44-ab3f-88404cd492ee
A 39-year-old man presents to his physician with the complaint of loss of peripheral vision. The subsequent magnetic resonance imaging (MRI) scan below demonstrates
Cerebral atrophy
Pituitary adenoma
Optic glioma
Pontine hemorrhage
1b
single
This T1-weighted sagittal MRI scan reveals a dumbbell-shaped homogeneous mass involving the sella turcica and the suprasellar region. This lesion is most consistent with a pituitary adenoma, a benign tumor arising from the adenohypophysis. Pituitary adenomas are the most common sellar lesion and constitute 10-15% of al...
Surgery
Nervous System
11390e5f-a182-4670-b1cb-1adccd75750c
The following are true of Mendelson's syndrome –
Critical volume of aspirate is 50 mls
Critical pH of gastric aspirate is 1.5
Onset of symptoms generally occurs within 30 minutes
Steroids have been shown to improve outcome
2c
multi
Symptoms of Mendelson's syndrome generally occurs within 30 minutes of aspiration. Critical pH is 2.5 and critical volume is 25 ml. Use of corticosteroid is generally not recommended.
Anaesthesia
null
3a6e9052-0da7-49da-ac04-863b91a89562
Commonest haematological malignancy in children is:
CLL
AML
CML
ALL
3d
multi
Acute lymphoblastic leukemia (ALL) is the most common malignancy of childhood, accounting for about 25% of all cancer diagnoses in patients younger than age 15 years. The peak age at onset is 4 years; 85% of patients are diagnosed between ages 2 and 10 years. Leukemia is defined by the presence of more than 25% maligna...
Pediatrics
null
57acc815-aa87-4417-9db6-26f6a456c054
Common sites of bleeding are: (PGI June 2008)
Woodruff plexus
Little's area
Brown's area
Vestibular Area
1b
single
Ans, B. (Little's area] Little's area or kiesselbach's plexus Q - This is the vascular area in the antero inferior part of nasal septum. It is the commonest1-1 site for epistaxis.Arteries Involved in Kisselbach's Plexus Formation"Four arteri es-anterior ethmoidal, septal branch of superior labialQ, septal branch of sph...
ENT
Nose and PNS
95e81367-e0bb-4cba-83f1-647af94138f2
The expression of the following oncogene is associated with a high incidence of Medullary carcinoma of thyroid-
P 53
Her 2 neu
RET protooncogene
Rb gene
2c
single
Harshmohan textbook of pathology 7th edition. RET gene is a proto oncogene normally code for receptor for growth factor ( RET receptor). Point mutation to this gene causes multiple endocrine neoplasi type 2A, type2B , medullary carcinoma of thyroid..
Pathology
General pathology
2467534e-db69-4826-9ebe-3f03adaad3ee
Most common cardiac anamoly associated with Noonan 's syndrome is
Aortic stenosis
Ventricular septal defect
Pulmonary stenosis
Atrial septal defect
2c
single
Most common cardiac anamoly associated with Noonan's syndrome is pulmonary stenosis.
Pediatrics
null
87c6d7dd-7ce6-47c3-9daf-4e2ad02a1652
1 day old m ale baby delivered by LSCS had swelling over back in midline.
Iron
Folic acid
Thiamine
Vit A
1b
single
Ans. is 'b' i.e., Folic acid o Folic acid supplementation decreases the incidence and recurrence of neural tube defects (NTD). Because the neural tube closes within the 1st 28 days ofconception, periconceptional supplementation is needed for prevention. It is recommended that women without a prior history of a NTD, ing...
Pediatrics
New Born Infants
0aed47ff-32bb-413d-9568-5deb6b84730b
Pheochromocytomas arise from:
Nonendocrine cells of the adrenal coex
Nonendocrine cells of the adrenal medulla
Neuroendocrine cells of the adrenal coex
Neuroendocrine cells of the adrenal medulla
3d
multi
Answer is D (Neuroendocrine cells of the adrenal medulla): Pheochromocytomas are catecholamine secreting tumors that arise from neuroendocrine chromaffin tissue in the adrenal medulla. The adrenal medulla consists of neuroendocrine cells called chromaffin cells Chromaffin cells are derived from primitive pheochromblast...
Medicine
null
371c2c9c-5b9b-4c5e-ab2d-423d6be70b81
Which of the following is NOT consistent with antemoem burns?
Presence of marked cellular exudates
Presence of line of redness
Blisters containing air and thin clear fluid with yellow base
Presence of increased enzymatic reaction at peripheral zone of burns
2c
single
In case of antemoem burns the blisters are filled with serous fluid and the base is red in colour. All the other options given are consistent with ante moem burns. Note that no inflammatory changes are seen in post-moem burns. Ref: Essentials of Forensic Medicine and Toxicology By Dr.K S Narayan Reddy, 21st Edition, Pa...
Forensic Medicine
null
f81cd95c-d6b4-4d16-9abd-3951de36ef9b
Parrot like repetitive speech is found in:
Autism
Cerebral palsy
Marfan's syndrome
Mental retardation
0a
single
Autism  spectrum  disorder  (ASD)  includes  three  neurodevelopmental disorders: autism disorder, Asperger syndrome, and pervasive development disorder (PDD). There are three levels of impairment noted.  The first notable impairment is social, which, in some cases is extreme,  with  lack  of  eye  contact  and  not  ...
Dental
null
086a0b17-4488-4ee9-a83c-d1b75fbeed66
Which is not a pathologic feature of H. pylori chronic gastritis -
Eosinophilic infiltrates
Intraepithelial neutrophil deposits
Affects intestinal gland formation in stomach
Subepithelial plasma cell deposits
0a
single
. Eosinophilic infiltrates
Pathology
null
7ec42bad-f304-4d2a-ac90-e749c49e07f3
A 36-year-old woman has become increasingly icteric for 1 month. She has had several bouts of colicky, midabdominal pain for 3 years. On physical examination, she has generalized jaundice with scleral icterus. Her BMI is 32. There is tenderness in the right upper quadrant, and the liver span is normal. A liver biopsy i...
Alkaline phosphatase
Ammonia
Antimitochondrial antibody
Hepatitis C antibody
0a
single
The findings suggest obstructive jaundice from biliary tract disease (e.g., gallstones). Elevation of the serum alkaline phosphatase level is characteristic of cholestasis from biliary obstruction. The alkaline phosphatase comes from the bile duct epithelium and hepatocyte canalicular membrane. The blood ammonia concen...
Pathology
Liver & Biliary Tract
a7c55dc3-84cc-4ec8-9b48-c9229a1a4c2e
Which X-ray needs to be taken for 16 year old male is ?
Wrist
Elbow
Shoulder
Ilium
1b
single
Ans. is 'b' i.e., Elbow
Forensic Medicine
null
f318a0ef-01f6-43e7-beff-de29694040ea
Symptoms of narcolepsy are all except
Cataplexy
Catalepsy
Daytime sleepiness
hypnagogic hallucinations
1b
multi
NarcolepsyThe classic tetrad of symptoms is:i. Sleep attacks (most common): ii. Cataplexy: iii. Hypnagogic hallucinations: iv. Sleep paralysis (least common): Ref: A Sho Textbook of Psychiatry, Niraj Ahuja, 7th Edition, pg. no. 138
Psychiatry
Sleep disorders and eating disorders
c452015a-5daa-46ed-b7a6-abd4724f06a0
In hemoglobin, the innate affinity of heme for carbon monoxide is diminished by the presence of -
His F8
His E7
Gly B6
Thr C4
1b
single
Isolated heme binds carbon monoxide (CO) 25,000 times more strongly than oxygen. However, in myoglobin and hemoglobin, heme binds carbon monoxide to only about 200 times more strongly than oxygen. This is because of distal histidine (His E7 of protein part of hemoglobin and myoglobin create a hindered environment which...
Biochemistry
null
b30b00ff-501e-41cd-b970-d1b8e88867a3
The key cell types involved in the acquired immunity include all EXCEPT:
B lymphocytes
Erythrocytes
T lymphocytes
Antigen presenting cells (APC)
1b
multi
The main physiological role of red blood cells (RBCs), or erythrocytes is to transport gases (O2, CO2) from the lung to the tissues and to maintain systemic acid/base equilibria.  In addition, RBCs are well equipped with antioxidant systems, which essentially contribute to their function and integrity. They are not inv...
Microbiology
null
517972b9-93be-4904-8025-4291e8fc4f1e
Screening is not recommended if -
Prevalence of disease is high
Life expectancy can be prolonged by early diagnosis
Diagnostic test should be available
Diseases with no latent period
3d
single
Ans. is 'd' i.e., Disease with no latent period o The disease to be screened should fulfil the following criteria before it is considered suitable for screening:-The condition sougth should be an important health problem (in general, prevalence should be high).There should be a recognizable latent or early asymptomatic...
Social & Preventive Medicine
Screening for Disease
6a407698-2895-4bd7-b962-5b201b48b308
Aminoacyl t-RNA is not required for
Proline
Lysine
Hydroxylysine
Methionine
2c
single
The enzymes aminoacyl tRNA synthetases activate the amino acids. The enzyme is highly selective in the recognition of both the amino acid and the transfer RNA acceptor. There is at least one tRNA for each of the 20 amino acids. Eg: hydroxylysine is the active form of lysine .hence not recognised by tRNA The D arm of tR...
Biochemistry
Metabolism of protein and amino acid
bf442290-30a0-4fc2-be12-4fdaf82c1052
Maximum infection of CMV is seen after what duration post transplantation ?
Immediate
< 1 month
1-4 months
> 6 months
2c
single
.Therapeutic invasive procedures may be in the form of IV cannula, bladder catheter, tracheostomy and other minor surgical procedures which permit the skin organisms like staphylococcus epidermidis to penetrate the skin and invade the deeper tissues. Organisms Bacteria: Gram-negative: E. coli, Pseudomonas, Klebsiella, ...
Surgery
Urology
830b248a-d95b-45af-9257-6eae0efccd72
What is the treatment of a child with supraventricular tachycardia?
Adenosine
Digoxin
Sotalol
Flecainide
0a
single
Ans. is 'a' i.e., Adenosine Treatment of supraventricular tachycardias in childreno In severe haemodynamic compromise, or if ventricular tachycardia is suspected, tachycardia should immediately be terminated by external cardioversion during deep sedationo Vagal manoeuvres are effective in patients with atrioventricular...
Pediatrics
Cardiac Therapeutics
81fd3ae7-1e8a-4e82-b1ac-977b6e781419
Gene for Wilms tumor iis located on
Chromosome 1
Chromosome 10
Chromosome 11
Chromosome 12
2c
single
characterized by Wilms tumor, aniridia, genital anomalies, and mental retardation. Their lifetime risk of developing Wilms tumor is approximately 33%. Individuals with WAGR syndrome carry constitutional (germline) deletions of 11p13. Studies on these patients led to the identification of the first Wilms tumor-associate...
Anatomy
Urinary tract
0aec6663-d0df-4115-b513-402586daf3dd
How much is punishment for sex determination -
3 years
5 years
7 years
9 years
0a
single
Ans. is 'a' i.e., 3 yearso According to pre-conception and pre-natal diagnostic techniques (prohibition of sex selection) act 2002, sex detection can lead to a fine of Rs. 10,000 and up to three years Inprisonment for a first offence, with greater fines and longer terms of imprisonment for repeated offenders.
Forensic Medicine
Misc.
836ce8d1-4690-48a5-ac85-b84d4c9f8563
Most impoant layer of a slow sand filter is ?
Vital layer
Sand bed
Filter system
Raw water
0a
single
Ans. is 'a' i.e., Vital layer o This is confusing one because of the following statements of Park. "The most impoant pa of the filter is the sand bed" - Park "The vital layer is the hea of the slow sand filter" - Park o Following statement may help in choosing the answer : ? "Vital layer is the layer that provides the ...
Social & Preventive Medicine
null
e6f11baf-c966-4521-bc87-25e8fb2ab686
All are features of tabes dorsalis, except -
Ataxia
Argyll Robertson's pupil
Bladder disturbances
Hyperreflexia
3d
multi
null
Medicine
null
4e909f68-d30e-4fd3-8d2f-b628b2c310f5
Micturition centre is present in -
Lateral temporal cortex
Medial temoral cortex
Lateral frontal cortex
Medial frontal cortex
3d
single
Ans. is 'd' i.e., Medial frontal cortex o Micturition centers are located in the brain-stem and cerebral cortex.1) In cerebral cortex (cortical center) : A cortical center for voluntary control of initiation and cessation of micturition is located in the superior frontal gyrus on medial surface (medial frontal cortex)....
Physiology
Nervous System
d747eea5-2998-4c0d-9ad2-a20d435a94ff
During an operation, if a pair of scissors is left in abdomen, the doctrine applicable is: JIPMER 10
Res integra
Res gestae
Res ipsa loquitor
Res judicata
2c
single
Ans. Res ipsa loquitor
Forensic Medicine
null
1e760ab5-a127-4a3a-aad7-fa755baafe7c
Hypophosphatemia is seen in all except-
Acute renal failure
Rickets
Respiratory alkalosis\/COPD
Chronic alcoholism
0a
multi
<P>Improved medical management of chronic kidney disease now allows many patients to survive for decades and hence time enough to develop features of renal osteodystrophy, which must be controlled to avoid additional morbidity. Impaired production of 1,25(OH) 2 D is now thought to be the principal factor that causes ca...
Medicine
Endocrinology
4fb5852f-aeee-4390-bdd3-46f16022a6ed
Bell's palsy not responding to the steroid. What will be the further line of management -
Increase the dose of steroid
Vasodilators and ACTH
Surgical decompression
Electrophysiological nerve testing
3d
single
If the patient of Bell's palsy is not responding to conservative treatment, electrodiagnostic study (electrophysiological study) should be done. The electrodiagnostic study includes electromyography (EMG), Electroneurography (ENG), minimal excitability test and maximal excitability test. Surgery is reserved for those w...
ENT
null
a818fc9d-7f8b-4e93-b984-f728f3742795
Not attached on medial border of scapula ?
Serratus anterior
Levator scapulae
Rhamboides major
Teres major
3d
single
Ans. is 'd' i.e., Teres majorMuscles attached to scapula are :-Coracoid process :- Tip of the coracoid process gives origin to coracobrachialis (medially) and sho head of the biceps laterally.The upper surface receives inseion of pectoralis minor.Spine of scapula and acromion process :- There is origin of Deltoid and i...
Anatomy
null
e2e62c46-db9d-4c67-bf48-d0d6626d5def
All is true about Giant cell arteritis except -
Most commonly involved artery is abdominal aorta
Involves large to small sized arteries
Granulomatous inflammation
Segmental nature of the involvement
0a
multi
Giant cell arteritis (Temporal arteritis) It is the most common form of systemic vasculitis in adults, is an acute and chronic, often granulomatous, inflammation of arteries of large to small size. It affects principally the arteries in the head-especially the temporal arteries—but also the vertebral and ophthalmic ar...
Pathology
null
3e141dc2-8561-4ec8-a2cc-19299a0a005d
All tests are used for infanticide except ?
Ploucquet test
Fodere's test
Gettler's test
Raygat's test
2c
multi
Ans. is 'c' i.e., Gettler's test Tests used in infanticide (for respiration) Ploucquet's test : Weight of lung is measured in relation to body wieght. Before bih weight of lung is 1/70 of body weight and after respiration it becomes 1/35 of body weight due to increased blood flow in lung beds. Static test or Fodere's t...
Forensic Medicine
null
409c4cdc-4c81-4c4b-a194-f063caee71a9
A female Mamta, 26 year old presented with gradually increasing respiratory distress since 4 days. She gives history of hospitalisation and mechanical ventilation with orotracheal intubation for 2 weeks . Now she is diaganosed as having severe tracheal stenosis. What would be the next line of management -
Laser excision and stent insertion
Steroids
Tracheal dilatation
Tracheal resection and end to end anastomosis
3d
multi
null
ENT
null
39f2fb0f-6818-429f-a93f-9aab29782c3c
MRI scan of a mentally retarded child with recurrent seizures and hemangioma. Diagnosis is?
Epiloias
Encephalofacial angiomatosis
Louis Bar syndrome
Neuronal ceroid lipofuscinoses
1b
multi
Ans. (b) Encephalofacial angiomatosis.* The CT scan shows extensive intracranial calcification which will lead to seizures, paralysis and hemiatrophy. The presence of hemangioma shows presence of Sturge-Weber syndrome called as encephalofacial angiomatosis.* Epilolia is alternative term for tuberous sclerosis.* Louis b...
Unknown
null
574515d5-6f1a-49ff-bfeb-cb7ef8f87f26
At t = 0 there are 6 x 1023 radioactive atoms of a substance, which decay with a disintegration constant (A,) equal to 0.01/sec. What would be the initial decay rate?
6 x 1023
6 x 1022
6 x 1021
6 x 1021
2c
single
Ans. 6 x 1021
Radiology
null
dd4b1f96-4e1a-4136-8ecd-3ede17ebabfd
Uremic complications typically arise during which of the following phases of Renal Failure:
Initiation
Maintenance
Diuretic Phase
Recovery Phase
1b
multi
Answer is B (Maintenance) Uremic complications and Electrolyte imbalance typically arise during the Maintenance Phase of Acute Renal Failure (Also known as Oliguric Phase). Maintenance phase refers to the phase of Renal Failure in which the renal injury becomes established. It is also known as the Oliguric Phase. Durin...
Medicine
null
5f1b79d8-e5e2-4f43-b5a8-e53c562fe222
Normal saline is used as diluent in which vaccine?
Measles
Rubella
BCG
HAV
2c
single
Ans. is 'c' i.e., BCG BCG vaccine BCG vaccine is a live attenuated vaccine produced by `Bacille Calmette Guerin' an avirulent strain produced by 230 subcultures over a period of 13 years. Types of vaccine It is a live attenuated vaccine. There are two types of vaccine :- Liquid (fresh) vaccine Freeze dried (lyophilized...
Social & Preventive Medicine
null
950e6485-e5cb-4d18-bf8e-7eebee897f35
Which is the most common complication of GERD
Esophagitis
Strictures
Dental damage
Vocal cord damage
0a
single
Esophagitis is the most common complication
Surgery
null
a6c50309-d29b-453c-a34a-a7a813325e99
The rate limiting step in glycolysis is catalyzed by-
Pyruvate kinase
Enolase
Glucokinase
Phosphofructokinase
3d
multi
Ans. is 'd >a & c' i.e., Phosphofructokinase > Pyruvate kinase & Giucokinase o Phosphofructokinase, giucokinase and pyruvate kinase are rate limiting enzymes of glycolysis. However,phosphofructokinase is the most important one."The irreversible phosphorylation reaction catalyzed by phosphofructokinase - l (PFK-1) is th...
Biochemistry
Glycolysis
fcf04ca7-cb24-4003-be02-0c053bc7a37e
Facial Nerve stimulation during testing of nerve indicated by contraction of muscle?
Temporalis
Masseter
Sternoleidomastoid
Orbicularis oris
3d
single
Orbicularis oris. Orbicularis oris is a facial muscle All facial muscles are supplied by facial nerve Temporalis & Masseter are supplied by Mandibular nerve Sternocleidomastoid is supplied by spinal accessory nerve
Anatomy
null
52efd5db-a990-4e5e-ad4b-8b459cc506a6
A 9 yr old child came to the dental clinic with spacing in anterior teeth. The line of treatment is
Fixed appliance
Removable appliance
Inclined plane
No treatment, observation of patient
3d
single
null
Dental
null
4733b7e7-ef75-4242-a145-eaf9d849cccd
Hepatic fibrosis is associated with which of the following
Medullary cystic kidney
ADPKD
ARPKD
Nephronopthosis
2c
single
S.NoDiseaseInheritance PathogenesisKidney featuresExtrarenal manifestations 1ADPKDADPKD1mutation in chr16pPKD2 mutation in chr 4qPKD1 produce polycystin-1PKD2 produce polycystin-2Enlarged kidneys, Multiple cysts in both kidneysDisease manifest only in adultsCysts in liver, spleen, pancreas and lung.Berry aneurysmMitral...
Pathology
Urinary tract
e3cc6c7a-dbb6-4f9a-b12e-318dd40b3809
Height of a newborn doubles at: September 2005, March 2010
1 year
2 year
3 year
4 year
3d
single
Ans. D: 4 year In general, length in normal term infants increases about 30% by 5 months and > 50% by 12 months; infants grow 25 cm during the 1st yr; and height at 4 yr is about double bih length.
Pediatrics
null
a6d1ee91-bfd8-4c67-937c-3dbe421d3dc3
Histological feature of lichen planus is ?
Acantosis
Interphase dermatitis
Non specific
Basal cell degeneration
3d
single
Ans. is `d>a' i.e., Basal cell degeneration > Acantosis The basic pathology in lichen planus is the damage to the basal cell layer of epidermis leading to hydropic degeneration of basal cells". --Venkataram Pie 59 Histopathologv in Lichen planus The basic pathology in lichen planus is the damage to the basal cell layer...
Skin
null
a19e691b-c0be-4107-9d05-f47417bbfff1
The Anaesthesia technique of choice in severely preeclamptic women for cesarean delivery -
Spinal Anaesthesia
Epidural Anaesthesia
General Anaesthesia
Pudendal shock
1b
single
The use of spinal anesthesia is discouraged in severe preeclampsia. Epidural anaesthesia is preferred since it has more hemodynamic stability. Regional anaesthesia spinal /epidural preferred over general anaesthesia for cesarean delivery since in pregnant female there are many risk associated with general anaesthesia.
Anaesthesia
Central Neuraxial Blockade
d636282b-ba48-4937-9526-9ec1d5610cb6
Tinel sign is seen in ?
Nerve degeneration
Nerve regeneration
Muscle degeneration
Muscle regeneration
1b
single
Ans. is 'b' i.e., Nerve regeneration Pathological changes after nerve injury After nerve injury, nerve first degenerates and then tries to regenerate. Nerve degeneration The pa of the neurone distal to the point of injury undergoes secondary or Wallerian degeneration; the proximal pa undergoes primary or retrograde deg...
Surgery
null
afa90c7c-3331-43f1-b2b4-b85596a83b4e
A patient is diagnosed to have CIN II. She approaches you for advice. You can definitely tell her the risk of malignancy as
15%
60%
30%
5%
3d
single
CIN I and CIN II, the lesions have a 5-10% chance to progress to a high grade lesion CIN III progressing to cervical cancer is almost 10-30% Transformation Rates Form low grade CIN to High grade CIN takes around 5-6 years From High Grade CIN to invasive cancer takes around 10 years time. HPV related cervical lesions oc...
Gynaecology & Obstetrics
Cervical Carcinoma
16288ecb-3b3c-4140-a0f4-72428bab6f7d
Which of the following is a feature of external haemorrhoids below the dentate line?
Painful
Ligation is done as management
Skin tag is not seen in these cases
May turn malignant
0a
single
Hemorrhoids are cushions of submucosal tissue containing venules, aerioles and smooth-muscle fibres. These anal cushions are found in the left lateral, right anterior and right posterior position. (3,7 and 11 o'clock position). External hemorrhoids located distal to the dentate line are covered by anoderm which is rich...
Surgery
null
10ed24cd-7081-440b-9d1d-fa40bf696bcc
Frie test is done in
Donovanosis
LGV
Syphillis
Leprosy
1b
single
B i.e. LGV
Skin
null
7fd01052-235b-4f21-8c6f-4f8b3bbb8b88
Anticoagulant effect of Warfarin is increased by all of the following EXCEPT:
Cimetidine
Phytonadione
Amiodarone
Phenylbutazone
1b
multi
Phytonadione is Vit K. It is used as an antidote in warfarin toxicity. From essential of medical pharmacology K D Tripati 7th edition Page no 613
Pharmacology
Hematology
7cb9318e-45d6-4727-b491-5bfe097050c5
Surgical neck fracture leads to all EXCEPT
Weakness of abduction
Deltoid muscle palsy
Teres major palsy
Teres minor palsy
2c
multi
Axillary nerve supplies: Deltoid (abductor of arm) and Teres Minor(lateral rotation) muscles. It winds up through surgical neck of humerus. So fracture of surgical neck damages axillary nerve causes: Teres minor palsy Deltoid palsy Abduction Of shoulder joint is damaged. Teres major is supplied by Lower subscapular ner...
Anatomy
Upper limb bones and muscles (proximal region) & Scapular movements
d0b09b32-fdc5-49b2-b608-62e4b65e623e
Percentage of GFR to renal plasma flow:
a.. 20%
b. 38%
c. 50%
d. 60%
0a
single
Ans. (a) 20%Ref: Guyton's physiology 11th ed. / 316* GFR Is About 20 Per Cent of the Renal Plasma Flow.* In an average adult GFR is about 125 ml/min, or 180 L/ day.* Renal plasma flow is 650ml/min* The filtration fraction is calculated as follows: Filtration fraction = GFR/Renal plasma flow* Therefore125ml/min---------...
Physiology
Glomerular Filtration, Renal Blood Flow, and Their Control
31c8fcc9-3ec6-443b-b4b9-a77930307ffe
Ossification at two months: JIPMER 12
Lunate
Capitate
Scaphoid
Hamate
1b
single
Ans. Capitate
Forensic Medicine
null
39f4fa0b-a85c-4776-a9ec-d44ff51f50ba
Primary Hyperoxaluria occurs due to defect in metabolism of
Cystein
Tryptophan
Tyrosine
Glycine
3d
single
Glycine is the amino acid that has a single hydrogen atom as its side chain. It is the simplest possible amino acid. The chemical formula of glycine is NH2‐CH2‐COOH. Glycine is one of the proteinogenic amino acids. It is encoded by all the codons starting with GG (GGU, GGC, GGA, GGG). Glycine is a colorless, sweet-tast...
Biochemistry
null
ca0cb8e9-18b9-4668-a9bd-5d50382eb1a6
A 45-year-old lady presents with persistent reflux symptoms. The most accurate investigation in establishing diagnosis before surgical treatment includes
Endoscopy
An UGI series
Esophageal manometry
Ambulatory pH monitoring
3d
single
investigations for GASTROESOPHAGEAL REFLUX DISEASE, *24 hours oesophageal pH monitoring - the gold standard. PPI should be stopped for 3 weeks prior to pH monitoring. *Barium study in head down position. * Endoscopy to exclude other disease and to assess any mucosal injury - red inflamed mucosa often with ulceration. S...
Surgery
G.I.T
f51049ce-d787-4dd4-964a-e4efbdfdc29d
Immuno-proliferative lymphoma presents with?
Chronic diarrhea
Obstruction
Peritonitis
Tenesmus
0a
single
Immunoproliferative small intestinal disease (IPSID), is a B cell tumor. The presentation includes chronic diarrhoea, steatorrhea associated with vomiting and abdominal cramps. IPSID presents with intestinal secretions of an abnormal IgA that contains a shoened heavy chain and is devoid of light chains. It is suspected...
Surgery
Vascular surgery
fa1797b1-e54a-48a9-af60-90a9c17170c8
Structure preserved in Radical Neck Node dissection:
Vagus nerve
Spinal Accessory Nerve
Internal Jugular Vein
Sterno cleido mastoid muscle
0a
single
Ans. (a) Vagus nerve(Ref Sabiston 20th Edition Page 794)* Standard RND (CRILE operation) removes nodal levels I through V and the sternocleidomastoid muscle, internal jugular vein, cranial nerve XI, cervical plexus, and submandibular gland.* Modified RND (Bocca Operation) preserves one or more of the three structures -...
Surgery
Oral Cavity
0d9a1ec3-d125-48f7-866a-9df76eafa8d9
The only cranial nerve which supplies a contralateral muscle is-
Third
Fourth
Seventh
Tenth
1b
single
"It is important to remember that cranial nerves never cross (except for one exception, the 4th cranial nerve) and clinical findings are always on the same side as the cranial nerve involved". —Clinical neurology
Ophthalmology
null