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135
412f43ca-7072-48ca-a894-4754abe86aa6
Precocious puberty may be seen in all of the following conditions except.
Granulosa - cell tumour
Head - injury
Corticosteroid intake
Hyperthyroidism
3d
multi
Ans. is d, i.e. HyperthyroidismRef: Jeffcoate 7th/ed, p116-118* Remember hypothyroidism and not hyperthyroidism causes precocious puberty.Reason:In hypothyroidism|| TSH|| Stimulation of FSH|Precocious pubertyIf precocious puberty is associated with delayed bone age it suggests primary hypothyroidism.Q
Gynaecology & Obstetrics
Sex Intersexuality
e8b27d33-207a-42ef-98d4-929ffa6ecb8e
For each description, choose the neurotransmitter with which it is usually associated: Ingestion of l-tryptophan increases the levels of this substance in the brain.
Serotonin
Norepinephrine
Dopamine
Acetylcholine
0a
multi
The amino acid l-tryptophan is the precursor for serotonin, which is a neurotransmitter needed for non-rapid-eye-movement (NREM) sleep as well as for mood and pain modulation. Up to 70 to 90% of brain norepinephrine is produced in the pontine nucleus, locus ceruleus. Dopamine is implicated in schizophrenia and also in ...
Psychiatry
null
62b10b19-428b-47bb-ae9a-4b8047d86242
In a child with respiratory distress, failure to thrive. His sweat chloride leveles were estimated 35 meq/L and 41 meq/L. What is next best test to do cystic fibrosis for diagnosis aEUR'
Nasal transmembrane potential difference
DNA analysis AF 508 mutation
CT chest
72 hour fecal fat estimation
2c
single
Trans epithelial nasal potential difference Diagnosis of cystic fibrosis Sweat chloride testing The sweat test is the standard approach to diagnosis. The diagnosis is made by elevated sodium and chloride level in the sweat > 60 meoll. Two tests on different days are required .for accurate diagnosis. A normal sweat chlo...
Pediatrics
null
c4e1ca2e-acab-443c-a8ca-90975da101e8
False about Turner's syndrome are all except:
Long stature
Normal gonads
Normal intelligence
Normal breast
2c
multi
The question is asking about true statement about Turner's syndrome out of all options. Only Normal intelligence is true and while all other options provide a false explanation of Turner's syndrome as explained below: Turner syndrome Genotype is X0 Female is affected Only monosomy compatible with life Have zero Barr bo...
Biochemistry
Genetic Disorders
b4fc5376-49ed-4246-8e1c-850c62c74c3b
Which one of the following statements is false with regard to Xanthogranulomatous pyelonephritis in children -
Often affects those younger than 8 years of age.
It affects the kidney focally more frequently than diffusely
Boys are affected more frequently.
Clinical presentation in chidren is same as in adults
0a
multi
Ans. is 'a' i.e., Often affects those younger than 8 years of age Xanthogranulomatous pyelonephritis is a form of chronic pyelonephritis characterised by destruction of renal parenchyma and the presence of granulomas, abscesses and collection of lipid laden foamy macrophages (foam cells). Xanthogranulomatous pvelonephr...
Pediatrics
null
fc7356c7-c56d-4292-9416-df2840202810
Burning epigastric pain is due to -
Vomiting
Reflux esophagitis
Duodenal ulcer
Gastric ulcer
1b
single
Ans. is 'b' i.e., Reflux esophagitis
Surgery
null
3ec18de7-5e18-4e04-a5c9-42a060daee36
Stunning of myocardium without any acute coronary syndrome is:-
Subendocardial infarction
Restrictive cardiomyopathy
Takotsubo cardiomyopathy
Transmural infarction
2c
single
A/k as broken hea syndrome High degree of emotional stress Increase catecholamines Coronary aery vasospasm | Ischemic dilatedcardiomyopathy M/E: Acute stage a necrosis + contraction band necrosis - Histologically, acute cases may show microscopic areas of necrosis characterized by myocyte hypercontraction (contraction ...
Pathology
NEET 2018
e64ecb94-045e-4fcc-ba77-affc936fdcc1
All of the following are indications for eicosanoids or their inhibitors EXCEPT:
Aboion
Essential hypeension
Patent ductus aeriosus
Transposition of the great aeries
1b
multi
PGE1 derivatives like misoprostol are used for aboion. PG inhibitors like indomethacin and ibuprofen are used for treatment of PDA. PGE1 derivative alprostadil is used to keep the ductus aeriosus open before surgery of patient with transposition of great vessels. PG like iloprost are indicated in pulmonary hypeension b...
Pharmacology
NSAIDs, Gout and Rheumatoid Ahritis
9e2f9e18-01d9-4640-bdf0-5321e41039b8
Following are the characteristics of Cryptococcus neoformans EXCEPT
Noncapsulated fungus infecting man
Causes meningitis
Melanin production related to virulence
Basidiomycetes yeast
0a
multi
null
Microbiology
null
1ad2c939-b8a6-42b7-bd50-e9d96b623a4a
"Sampling error" occurs due to the variation in results-
Between one sample and another
Between the observations of two individuals
Due to the use of many instruments in the study
Due to the multiple readings taken on the same instrument
0a
single
Taking repeated samples from the same population will result in a difference in the results obtained between samples; this is called SAMPLING ERROR. It occurs because data was gathered between samples rather than from the entire population. Ref: 25th edition, Park's Textbook of Preventive and Social Medicine, Page no. ...
Social & Preventive Medicine
Epidemiology
90ba63ac-0247-4b39-aaed-c9a64b03fa52
Most sensitive test for metastatic deposit is:
Isotope scan
CT scan
Skeletal survey
Tomography
0a
single
Ans. Isotope scan
Radiology
null
58e3ac7d-9908-4089-9a54-bc955fae3f45
Drumstick appearence is seen in :
Cl. tetani
Cl. tetanomorphum
Cl. sphenoids
All of the above
3d
multi
null
Microbiology
null
f4ab75fb-e50e-4c60-aefa-c51f1695ba51
Which is the teeth referred to if by haderup classification it is denoted as (- 4) ?
Upper canine
Lower first premolar
Upper second premolar
Lower first molar
1b
single
Ans. is 'b' i.e., Lower first premolar
Forensic Medicine
null
d326c818-0bf8-42fd-92a1-f6e0942fa1cf
A 47-year-old HIV-positive man is brought to the emergency room because of weakness. The patient has HIV nephropathy and adrenal insufficiency. He takes trimethoprim-sulfamethoxazole for PCP prophylaxis and is on triple-agent antiretroviral treatment. He was recently started on spironolactone for ascites due to alcohol...
Sodium polystyrene sulfonate (Kayexalate)
Acute hemodialysis
IV normal saline
IV calcium gluconate
3d
single
This patient has life-threatening hyperkalemia as suggested by the ECG changes in association with documented hyperkalemia. Death can occur within minutes as a result of ventricular fibrillation, and immediate treatment is mandatory. Intravenous calcium is given to combat the membrane effects of the hyperkalemia, and m...
Medicine
Kidney
4db4001c-bb56-45c6-8381-7476f01295de
Which metal poisoning can be detected analysing bone :
Arsenic
Nickel
Chromium
Lead
0a
single
A i.e. Arsenic
Forensic Medicine
null
477c9e67-2a90-4c0f-97bf-7cb2a99ba3ff
Kawasaki disease is associated with all except:
Erythema
Posterior cervical lymphadenopathy
Thrombocytopenia
Conjunctivitis
2c
multi
c. Thrombocytopenia(Ref: Nelson's 20/e p 1216-1217, Ghai 8/e p 632-633)Mnemonic:Diagnostic Criteria for Kawasaki DiseaseFever persisting at least 5 days with presence of at least 4 features out of 5 (CREAM):Conjunctivitis: Rash, Edema & erythema of palms & soles, Adenopathy and Mucosal involvement: Strawberry tongue
Pediatrics
New Born Infants
b7a644dd-cff6-45ac-9b95-af948ea20dad
Among Bipyridyl herbicides, 1) Diquat is only half as toxic as paraquat 2) Diquat doesnot produce pulmonary toxicity
Both are true
Both are false
1 is true, 2 is false
2 is true, 1 is false
0a
multi
Diquat is only half as toxic as paraquat Diquat doesnot produce pulmonary toxicity
Forensic Medicine
Toxicology - 1
ec5ec33d-aea1-47ea-85f9-81024eb62bbf
Which of the following is a new drug recently approved for treatment of neovascular age related macular degeneration?
Brolucizumab
Istradefylline
Lefamulin
Upadacitinib
0a
single
*Brolucizumab is a monoclonal antibody against VEGF. *It is recently approved for wet (neovascular) age related macular degeneration.* Istradefylline is adenosine A2 receptor antagonist. It is approved for off episodes in Parkinsonism* Lefamulin is a new antimicrobial that acts by inhibiting protein synthesis. It is ap...
Pharmacology
Targeted Anticancer Drugs and Immunosuppressants
38031385-ec88-4ffc-ad26-1b29b1c046ef
Cancer management in which of following malignancies has dramatically increased the survival?
Esophagus carcinoma
Glioblastoma multiforme
ALL in children
Cholangiocarcinoma
2c
multi
Ans. is 'c' i.e., ALL in children Prognosis of ALLThe survival rate has improved from zero four decades ago to 20-75 percent currently, largely due to clinical trials on new chemotherapeutic agents and improvements in stem cell transplantation (SCT) technology.Glioblastoma multiforme (grave iv) is an aggressive form of...
Pediatrics
Malignancies
5c9c9e06-f787-4ad1-abed-6ffd7f20b57b
Which of the following is not component of acinus?
Pulmonary lobule
Respiratory bronchioles
Alveolar ducts
Alveolar sac
0a
single
Ans. is `a' i.e., Pulmonary lobule o Pulmonary lobule is not a component of acinus, rather cluster of 3-5 terminal bronchioles with acinus form pulmonary lobule. Respiratory tract anatomy o Progressive branching of bronchi forms bronchioles. o Fuher branching of bronchioles leads to terminal bronchioles. o Terminal bro...
Pathology
null
101fda40-da68-4991-8889-087087872ab9
All are true regarding Tinea versicolor except:
Orange fluorescence inWood lamp examination
Caused by Malessesia globosa
Griseofulvin is the drug of choice
Both hypo and byperpigmented lesions
2c
multi
Ref: Fungal infections, hi: Thappa DM, editor. Essentials in Dermatology, 2ndedth, New Delhi: Jay pee brothers medical publishers (P) Lid 2009:57-7}.Explanation:Tinea VersicolorCausative agent: Pitryrosporuni orbiculare (Malassezia furfur)It is a superficial fungal infection of the skin caused by Malassezia furfur and ...
Unknown
null
10f0582d-bb90-414a-8e7c-ae61318b6203
External ballottement can be done after how many weeks of gestation: Manipal 10
6 weeks
16 weeks
20 weeks
24 weeks
2c
multi
Ans. 20 weeks
Forensic Medicine
null
1fcc9ad5-b213-4b38-9340-db07ad3ba3c4
Which of the following is initial investigation of choice for a patient presenting with solitary nodule of thyroid: March 2005
Thyroid function test
FNAC
Radionuclide scan
MRI
1b
single
Ultrasound is the preferred imaging modality for thyroid nodules, and the ultrasound guided fine needle aspiration biopsy (FNAB) is the preferred method of tissue.
Surgery
null
ca6fa22b-e904-47ea-9fbc-b3890aed6a70
A 26 year old man died suddenly during spoing activity. At autopsy the hea revealed chamber and septum Hyperophy. The most likely diagnosis is
HOCM
DCM
Arrhythmogenic cardiac problem
Restrictive cardiomyopathy
0a
single
Answer is A. (HOCM): Sudden death following competitive spos in young individuals is characteristic of hyperophic obstructive cardiomyopathy (HOCM). The presence of chamber and septal hyperophy on autopsy confirms the suspected diagnosis of HOCM
Medicine
null
f0d312f8-19d3-41b9-8ff0-09d8921d4d4e
Tertiary vitreous is represented by-
Zonular system
Ciliary body
Anterior uvea
Lens
0a
single
Ans. is 'a' i.e., Zonular system 'Tertiary vitreous indicates the zonular system. The primary and secondary vitreous are stages in development of vitreous. However the tertiary vitreous i.e. the zonules are named so only because of their proximity to the vitreous'* The tertiary vitreous or the zonular system includes :...
Ophthalmology
Vitreous
5db2457f-0c3b-474b-8e95-bc8ed552058d
All of the following are features of chronic tonsillitis except
Pus in crypts
Congestion of anterior pillar
Congestion of posterior pillar
Enlargement of jugulodigastric lymph nodes
2c
multi
Clinical features of chronic tonsillitis1 Recurrent attacks of sore throat or acute tonsillitis.2. Chronic irritation in throat with cough.3. Bad taste in mouth and foul breath (halitosis) due to pus in crypts.4. Thick speech, difficulty in swallowing and choking spells at night (when tonsils are large and obstructive)...
ENT
Ear
9c839c5d-dd32-44b3-8ca9-a7a99d36691b
Several segments of the polypeptide chain of integral membrane proteins usually span the lipid bilayer. These segments frequently (NOT RELATED)
Adopt an a-helical configuration
Contain many hydrophilic amino acids
Form covalent bonds with cholesterol
Contain unusually strong peptide bonds
0a
multi
.
Pharmacology
All India exam
aa54cfff-5ce6-4b08-88f1-5749aa90d953
Enzyme deficiency responsible for gout are all except:
PRPP synthase
Pseudogout enzyme
5 - phosphoribosyl amido transferase
Glucose 6 phosphatase
1b
multi
Ref: Harpers Illustrated Biochemistry,28th editionExplanation:Hyperuricemia - Uric acid level:Males > 7 mg / dLFemales > 6 mg / dLAccumulation of insoluble monosodium urate crystals in the synovial fluid causes inflammationAcute arthritis.Deposition in cooler areas - TophiRenal lithiasis.PRIMARY GOUT- CausesAbnormality...
Biochemistry
Urea Cycle and Disorders
2172f1dc-083a-4fae-9443-8a3a8ce09bc8
Dracanculosis elimination program, which of the following activities is not evaluated to know the extent of goal achievement ?
Provision of protected water sources
Health education
Chemical disinfection of water sources
Registration of new cases
3d
single
Ans. is 'd' i.e.,Registration of new casesThe extent to which Dracanculosis Medinensis Elimination program goals are achieved can be determind by calculating the the percentage of planned activities that are actually carried out. A list of these activities is as follows:Provision of protected water sources. Health educ...
Social & Preventive Medicine
null
5ce65f8c-c458-4a9e-a1ed-79e22578e9c1
A major causal factor in some cases of hypogonadism is
Reduced secretion of gonadotropin-releasing hormone (GnRH)
Hypersecretion of pituitary LH and FSH as the result of increased GnRH
Excess secretion of testicular activin by Seoli cells
Failure of the hypothalamus to respond to testosterone
0a
single
Reduced secretion of GnRH will result in extremely low levels of circulating LH and FSH, causing testicular atrophy, as in Kallmann's syndrome.
Gynaecology & Obstetrics
All India exam
cde571df-264d-413b-8e2d-548aed3c156a
Lumbar hemiveebra results due to the abnormal development of the following embryonic structure:
Dorsal sclerotome
Intermediate cell mass
Notochord
Ventral sclerotome
3d
single
The ventromedial pa of the somites is called the sclerotome. The cells of the sclerotome migrate medially. They surround the neural tube and give rise to the veebral column and ribs. The veebral body may ossify from two primary centers which soon fuse. One of these pas may fail to develop, resulting in only half of the...
Anatomy
null
150acfe8-76be-4bd2-a5a4-6c5906ec882d
Which of the following is the most common central nervous system parasitic infestation-
Echinococcosis
Sparganosis
Paragonimiasis
Neurocysticercosis
3d
single
null
Medicine
null
744a9104-0b79-4273-8d00-51030cd59660
All are used to treat hypercalcemia, EXCEPT :
D-penicillamine
Corticosteroid
Biphosphonate
Mithramycin
0a
multi
Ans. is ' a' D-penicillamine D-penicillamine has no role in the treatment of hypercalcemiaTreatment of hypercalcemia*Hydration with salineForced diuresis, saline plus loop diureticBiphosphonates - Etidronate and pamidronateCalcitoninSpecial used therapies are :Phosphates (Oral and Intravenous)GlucocorticoidsGallium nit...
Pharmacology
Chelating Agent
30690d19-63f8-48bd-bd66-d565ac8375fa
Crystal of pseudogout is made up of ?
CPPD
Urate
Calcium carbonate
Xanthine
0a
single
Ans. is 'a' i.e., CPPD
Surgery
null
c21e7277-2c91-4546-87d4-8298d7aa5479
Defect in Amyloid protein folding occurs in:
Alzheimer disease
Creutzfeldt-Jakob disease
Scrapie disease
Bovine spongiform encephalopathy (BSE)
0a
single
PROTEIN MISFOLDING AND DISEASES- (1) Amyloidosis - Amyloids is used to refer to the altered proteins (with beta-sheets) that accumulate in the body, paicularly in the nervous system Alzheimer's disease is a neurodegenerative disorder Accumulation of beta amyloid. Other example of amyloidosis:- Type Protein Implicated P...
Biochemistry
DNB 2018
7a614537-1104-4731-baa8-f41b6346b1a6
Bacteria is not shed in -
Carrier state
Latent infection
Incubation period
Subclinical infection
1b
single
in latent infection the host does not shed the infectious agent which lies dormant within the host without symptoms.and often without demonstrable presence in blood ,tisssues ,or bodily secretions of the host.latent infection occurs in herpes simplex,zinser disease,infections due to slow viruses ,ancylostomiasis,etc.th...
Social & Preventive Medicine
Epidemiology
75d3427d-475a-4e65-bba2-f8a8c37da572
Possible mechanisms causing pain in patients with endometriosis include all except
Local peritoneal inflammation
Deep infiltration with tissue damage
Collection of shed menstrual blood in endometriotic implants
Septic seeding of the endometriotic implants
3d
multi
Possible mechanisms causing pain in patients with endometriosis include:- Local peritoneal inflammation, Deep infiltration with tissue damage, Adhesion formation, Fibrotic thickening, Collection of shed menstrual blood in endometriotic implants, resulting in painful traction with the physiologic movement of tissues.
Gynaecology & Obstetrics
Endometriosis & H
e4527fd6-f133-496a-8d55-35af6d4cee68
Most common malocclusion found in people is:
Class I with incisor crowding
Class II division 1
Class II division 2
Class III
0a
single
Class I Malocclusion  A large sampling of our population would show that a majority of the malocclusions are Angle’s Class I malocclusion.
Dental
null
f0bd398f-3d90-4de0-9b9e-58b6c179c1ac
Accidental small splenic rupture is treated with -
Catgut sutures
Silk sutures
Omental patch
Catgut suturing with omental patch
3d
multi
The placement of a simple monofilament suture through the splenic parenchyma (often in a mattress technique and incorporating a piece of Gelfoam or an omental patch placed at the site of bleeding) will often bring about satisfactory hemostasis.
Surgery
null
698220f5-3f8d-4d96-8b29-55c18b9dff28
In presence of secondary sexual characters cause screening for primary amenorrhea is done at
12years
14 years
16 years
18 years
2c
single
Primary amenorrhoea is defined as the absence of secondary sexual characters by 14 yrs of age or absence of menarche in the presence of secondary sexual characters till 16 yrs of age, In the sequence of pubeal development the changes are as follows thelarche, increased growth spu, pubarche, menarche. As menarche is the...
Anatomy
All India exam
16e6a51f-4648-44c8-be33-464a48da5e87
The primary function of basal ganglia is
Preprogramming of voluntary activity
Control of equilibrium
Sensory integration
Short term memory
0a
single
(A) Preprogramming of voluntary activity > Basal ganglia are involved in the planning and programming of movement or, more broadly, in the process by which an abstract thought is converted into voluntary action. Basal ganglia also play major role in some cognitive processes.
Physiology
Nervous System
ad2c2f55-3964-4cc9-b6c4-e30c9c3edafc
Diagnostic of antemortum drowning -
Palatauf's hemorrhage
Weeds and grass in clenched hands
Emphysema aquosum
Water in esophagus
1b
single
Ans. is 'b' i.e., Weeds and grass in clenched hands PM findings of drowningExternal findingsA) Specific (diagnostic)i) White, fine, lathery, abundant and tenacious froth at nose and mouth which increases on chest compression.ii) Weeds, grass, plants, mud or stones in tightly clenched hands.B) Non-specifici) Washer woma...
Forensic Medicine
Injuries
f7c617e5-70e0-4ade-9c4c-9e9ad2045ea0
Endoscopic stapling procedure would be ideal in
Pharyngeal pouch
Gastric ulcer
Esophageal varices
Perforation
0a
single
Stappling of diveicula is done as a treatment procedure for pharyngeal pouch(Zenker's diveiculum). Other method is Dohlman's procedure. In this Pouch is excised using double lipped endoscopy. Cautery or laser is used. It is quicker procedure with sho duration of anaesthesia, with fast recovery. Other treatment option i...
Surgery
G.I.T
d032681e-0d7c-4986-8870-d7160669501b
Which artery is dissected most commonly following arteriography by femoral route –
Celiac trunk
Superior mesenteric artery
Inferior mesenteric artery
Gastroduodenal artery
2c
single
null
Radiology
null
d486fcbd-ea94-4d1d-9497-dc70402ae335
Which of the following is poor prognostic factor in a child with ALL?
Age 2-8 yrs
Total leucocyte count < 50,000
t (9;22); t (4;11); t (1;19)
Absent blasts in peripheral smear
2c
multi
Specific chromosomal translocations in ALL,including t(8;14,associated with Burkitt leukemia),t(4;11) in infant leukemia,t(9,22)translocation that forms the Philadelphia chromosome,t(1,19) translocation associated with probable CNS relapse,are associated with a poor prognosis.The age group of 2-10 yrs have satisfactory...
Pediatrics
Childhood tumors
86ba5921-fef1-4edc-8aa4-13878099ffae
A 74 yr old male patient was brought to the OPD by his daughter complaining of urinary incontinence and ataxia, also he has difficulty in calculating simple arithemetics and memory loss. What is the probable diagnosis
Normal pressure hydrocephalus
Vascular dementia
VIT B12 dofficiency
Tabes dorsalis
0a
single
CLINICAL FEATURES IN NORMAL PRESSURE HYDROCEPHALUS Difficulty walking. This problem can be mild or severe. ... Dementia. This often involves confusion, sho-term memory loss/forgetfulness, trouble paying attention, changes in mood, and a lack of interest in daily activities. Problems with bladder control. REF : HARRISON...
Medicine
All India exam
d992f842-02de-4bf4-a5fc-9998c0b2f806
Commonest presentation of Ca rectum is:
Diarrhoea
Constipation
Bleeding P/R
Feeling of incomplete defaecation
2c
single
Bleeding is the earliest and most common symptom. Often the bleeding is slight in amount. Alteration in bowel habit is the next most frequent symptom. An early morning urgency may occur but he passes only mucus & blood (early morning bloody diarrhea). An annular carcinoma at pelvi-rectal jn. may lead to constipation & ...
Surgery
null
34821cb1-5d8f-4f48-b608-bab4ec260f2d
Cavity conditioning in ART is done by
Cocoa Butter
Petroleum Jelly
37% Phosphoric Acid
10% Polyacrylic Acid
3d
single
null
Dental
null
24198525-5a5e-46e6-97ef-a1874036e687
All of the following factors tend to increase the volume of distrubtion of a drug except
High plasma protein binding
Low ionization at physiological pH values
High lipid solubility
High tissue binding
0a
multi
Ref-katzung 10/e per,35 If a drug is highly bound to plasma proteins ,it is more likely to stay in blood.thus it's Vd will be less . Low ionization ours the distribution of a drug because unionized molecules can cross the membrane of blood vessels and the tissue More lipid soluble drugs can easily cross the membrane an...
Anatomy
Other topics and Adverse effects
8ff8d44d-7bb8-49b0-803a-499b7598f090
All the following are characteristic of Dhatura poisoning except:
Delirium
Diplopia
Pin-point pupils
Dysphagia
2c
multi
C i.e. Pinpoint pupil
Forensic Medicine
null
33198589-c4ec-4ab8-abc0-938f6bc9d43a
A dead body is having cadaveric lividity of bluish green colour. The most likely cause of death is by poisoning due to:
Hydrocyanic acid
Hydrogen sulphide
Oleander
Sodium nitrite
1b
single
Colour of post-moem staining in poisoning- 1) Dark brown or yellow- Phosphorus or acute copper poisoning, 2) Cherry red- CO & Cold storage, 3) Bluish-green- H2S, 4) Bright red- HCN/ Cyanides, 5) Chocolate/Red-brown coloured- Nitrites/Nitrates, aniline, Nitrobenzene, Acetanilide, Bromates, Chlorates (due to formation of...
Surgery
null
400304d8-404a-46e5-8af9-3c13d935627f
A 20 year old female was diagnosed with granulose cell tumor of the ovary. Which of the following bio markers would be most useful for follow-up of patient?
Inhibin
CA50
CA 19-9
Neuron – specific enolase
0a
single
Granulosa cell tumor • The most common type of ovarian tumor that is composed of cells that stain positively with inhibin. • Histologically, the cells may form Call-Exner bodies • The tumor cells may secrete estrogens and cause precocious sexual development in girls or increase the risk for endometrial hyperplasia and ...
Pathology
null
5673b709-0a34-42a4-9e87-a6ad1db63763
A patient with bilirubin value of 8mg/dl and serum creatinine of 1.9 mg/dl is planned for surgery. What is the muscle relaxant of choice in this patient?
Vecuronium
Pancuronium
Atracurium
Rocuronium
2c
single
Atracurium is the muscle relaxant of choice in patients with liver and renal failure because these drugs undergo extensive plasma degradation. Atracurium undergoes esterase degradation and spontaneous breakdown at physiologic pH and temperature called Hoffman elimination. Metabolism of atracurim yields a metabolite cal...
Anaesthesia
null
d9600222-5c5c-423e-8f73-1de9102fb20c
The parotid duct is known as
Whaon's duct
Stenson's duct
Duct of Santorini
Duct of Wirsung
1b
single
ParotidStenson's ductOpens at upper 2nd molar toothSubmandibular glandWhaon's ductOpens into the papilla just lateral to the frenulumSublingual glandDucts of RiviniusNumerous excretory ducts(Ducts of Rivinus), directly into the oral cavityDuct of Wirsung is major pancreatic ductDuct of Santorini is accessory pancreatic...
Surgery
Head and neck
557158ce-d347-4da0-9c8c-1e662d6ab733
Sure sign of malignancy is
Mitosis
Polychromasia
Nuclear pleomorphism
Metastasis
3d
single
Ref Robbins 8/e p269; 9/e p272 CHARACTERISTICS OF BENIGN AND MALIGNANT NEOPLASMS Nothing is more impoant to the patient with a tumor than being told: "It is benign." In general, benign tumors appear to be genetically "simple," harboring fewer muta- tions than cancers, and genetically stable, changing little in genotype...
Anatomy
General anatomy
c394928d-d11e-48a7-9605-13778c4e13ef
False statement regarding aneurysms is -
True aneurysm contains all the 3 layers
In dissecting aneurysms media is defective
Charcot bouchard aneurysms are seen in brain
Saccular aneurysms involves the entire circumference
3d
multi
An aneurysm is an outward bulging, likened to a bubble or balloon, caused by a localized, abnormal, weak spot on a blood vessel wall. leading to uncontrolled bleeding. Although they may occur in any blood vessel, paicularly lethal examples include aneurysms of the Circle of Willis in the brain, aoic aneurysms affecting...
Medicine
C.V.S
02c1d9c8-5e09-4650-a157-444f5d1bbb3d
Best X-ray view taken to visualize Maxillary sinus-
Water's view
Caldwell's view
Lateral view
Occlusive anterior view
0a
single
Figure: Water's view WATER /OCCIPITOMENTAL VIEW:Best view for maxillary sinus. Waters view with open mouth is called Pierres View CALDWELL VIEW/OCCIPITOFRONTAL VIEW: Best view for frontal sinus. LATERAL VIEW: Sella, Sphenoid sinus Points to be remembered: Area View Superior orbital fissure Caldwell view Inferior orbita...
Radiology
X-RAYS
0d735ba7-3012-40a0-836a-ffc450e763e4
Quality indicator of MCH services -
IMR
MMR
CMR
None
0a
multi
Park's textbook of preventive and social medicine 23rd edition. * IMR is an impoant indicator of health status of a community and effectiveness of MCH services in paicular.
Social & Preventive Medicine
obstetrics,pediatrics and geriatrics
4a0584c9-0143-4e15-8a59-deac805bf434
Facial nerve palsy at sternomastoid canal can cause-
Loss of corneal reflex at side of lesion
Loss of taste sensation anterior 2/3 of ipsilateral tongue
Loss of lacrimation at side of lesion
Hyperacusis
0a
single
Below stylomastoid foramen, facial nerve gives following branches: - Posterior auricular branch, muscular branches (stylohyoid & posterior belly of digastric) and terminal (peripheral) branches. Lesion at sternomastoid foramen : - i)    Will spare Greater superficial petrosal nerve → Lacrimation present. Nerve to sta...
ENT
null
10d41fdc-8bb6-403c-ad5a-2a9621372628
In case control study, the risk is calculated by-
Relative risk
Attributable risk
Cross product ratio
None
2c
multi
Also known as odds ratio Measure of strength of relations between risk factor and outcome. The disease being investigated is very rare The cases must be representative of those with disease The controls must be representative of those without disease Ref: 25th edition, Park's Textbook of Preventive and Social Medicine,...
Social & Preventive Medicine
Epidemiology
7f0e3e00-8e21-4b1e-aa9c-46b5b2f64a23
Alternate contact points along shaft are seen in
K3
RACE
Real World Endo
Light speed
2c
single
The blank design employed by the Endo Sequence file is a triangle with alternating contact points (ACP) along the instrument's ,hunk. The Endo Sequence file undergoes electropolishing and the result is visible in its mirror-like finish that remains sharper longer and mays cleaner during use. About RACE: Design of the r...
Dental
null
fd325071-755b-4954-8f2d-30f8b8d82a1f
Tear drop fracture of lower cervical spine implies -
Wedge compression fracture
Axial compression fractures
Flexion-rotation injury with failure of anterior body
Flexion compression failure of body
3d
single
Severe injuries are due to axial compression of the cervical spine, usually in diving or athletic accidents . If veebral body is crushed in neutral position of the neck the result is burst fracture. *With combined axial compression & flexion ,an antero- inferior fragment of the veebral body is sheared off , producing e...
Orthopaedics
Spinal injuries
a5de5a36-ee10-4187-9253-6d10ac94c1b0
A patient with mild congestive hea failure is treated with high-dose furosemide and diuresis 3 liters of fluid.A complete blood count (CBC) taken before the diuresis shows an RBC count of 4 million/mm3; a CBC taken after diuresis shows a RBC count of 7 million/mm3. Which of the following is the most likely explanation?
Cyanotic hea disease
Increased erythropoietin
Polycythemia vera
Relative polycythemia
3d
single
This is an example of relative polycythemia, in which there is an increased hematocrit or RBC count without a true increase in the total number of body RBCs. What usually happens in these cases is a significant reduction in plasma volume due to processes such as dehydration, vomiting, diarrhea, or diuresis. Cyanotic he...
Physiology
null
273c97d3-a0dc-4c8e-9024-134beb5725aa
Amoebic liver abscess can be diagnosed by demonstrating -
Cysts in the sterile pus
Trophozoites in the pus
Cysts in the intestine
Trophozoites in the feces
1b
single
Trophozoites may be demonstrated in the liver biopsy from cases of amoebic hepatitis. Diagnostic liver aspiration can be performed if liver aspiration can be performed if liver abscess is present.Trophozoite can be demonstrated in the aspirate by wet preparation.Aspirations from the center of liver abscess may not show...
Microbiology
parasitology
6f54bdb7-c07d-4d83-a8d7-c856795d1dbe
Most B/L multifocal retinoblastoma require
Chemotherapy
Radiotherapy
Enucleation
Multi Modality therapy
3d
single
D i.e. Multi Modality therapy Multi Modality Therapy Most children with bilateral retinoblastoma, multifocal RB, or bothQ, and occasion children with unilateral RB, are managed by multimodality therapy.
Ophthalmology
null
24586be8-ee94-4547-9ccd-1c68b94598c9
Osteomas common in which of the following sinus?
Frontal
Ethmoid
Maxillary
D Sphenoid
0a
single
Ref: Diseases of the Ear Nose and Throat by PL Dhingra.5th edn .2010 page page 219Explanation:Sinus OsteomasOsteomas are most common in Frontal followed by ethmoid and then maxillary sinusesMost are asymptomatic and detected incidentally on radiology of the sinusesMay become symptomatic when they obstruct the sinus Ost...
ENT
Nose and PNS
6774e87c-00ba-49bf-924c-a080d1b9e5de
Which of the following is level III lymph nodes?
Central
Apical
Interpectoral
Anterior
1b
single
Apical also known as subclavicular is level III lymph node.
Surgery
null
57f6df1a-5b44-43ee-b11a-b9d9fd0f4512
Giardiasis is associated with -
Common variable immunodeficiency
C1 esterase deficiency
C8 deficiency
Anaemia
0a
single
G. lamblia is seen typically within the crypts in the duodenum. It does not invade tissues lead to mucus diarrhoea, dull epigastric pain and flatulence. The diarrhoea in some cases may be steatorrhoeic with excess mucus and fat, but no blood. The incubation period is variable, but is usually about 2 weeks. Enhanced sus...
Microbiology
parasitology
27a2e7b1-c736-41ab-ba0b-8a03ab1f6bf7
Which of the following stages of demographic cycle has expanding population?
Second
Third
Both of the above
None of the above
2c
multi
Stages of demographic cycle are: First stage (High stationary) Second stage (Early expanding) Third stage (late expanding) Fouh stage (Low stationary) Fifth stage (declining) Ref: Park, 22nd edition pg: 441
Social & Preventive Medicine
null
4a73f133-21c3-41d2-b92a-b48d61fc8abf
NAD+ reduced by all of the following enzymes except:
Alpha ketoglutarate dehydrogenase
Iso-citrate dehydrogenase
Malate dehydrogenase
Succinyl dehydrogenase
3d
multi
Ans. D. Succinyl dehydrogenaseNiacin acts as electron acceptor for the following enzymes:Isocitrate dehydrogenaseAlpha ketoglutarateMalate dehydrogenase
Biochemistry
Carbohydrates
ee2c79f4-7275-4a5b-9e07-64cdc9def892
Enzyme deficiency in Tarui disease is
Glucose-6-phosphatase
Muscle and erythrocyte phosphofructokinase 1
Lysosomal a1 - 4 and a1 - 6 glucosidase
Liver phosphorylase kinase
1b
single
Type name Enzyme Deficiency Clinical Features VII Tarui disease Muscle and erythrocyte phosphofructokinase 1 Poor exercise tolerance Muscle glycogen abnormally high (2.5%-4%) Blood lactate very low after exercise Also hemolytic anemia Reference: Harper; 30th edition; Table: 18-2; Page no: 179
Biochemistry
Metabolism of carbohydrate
e025bee6-cd7d-4ae8-8803-efa9d84bba52
In benign hypeension commonest vascular pathology is
Atherosclerosis
Fatty mfilitraion of intima
Fibmoid necrosis
Hyaline aeriosclerosis
3d
single
In smaller aeries (< 1 mm), hyaline aeriosclerosis occurs in the wall, the lumen narrows and aneurysms may develop. Widespread atheroma develops and may lead to coronary and cerebrovascular disease, paicularly if other risk factors (e.g. smoking,diabetes, hyperlipidaemia,) are present.These structural changes in the va...
Medicine
C.V.S
fe9ac283-02c9-40da-bc73-a3279b24f79d
Which among the following statements is true regarding chalazion:
Mucous cyst
Sebaceous cyst
Due to staphylococcal infection
Recurrence may imply malignancy
1b
multi
B i.e. Sebaceous cyst Also known as meibomian or tarsal cyst is chronic, sterile lipogranulomatous inflammation of meibomian gland Predisposing factors Clinical features Course & Complication Treatment Patient with acne - Gradually enlarging - Resolve spontaneously - In small, soft & recent chalazion conservative rosac...
Ophthalmology
null
7517690e-c518-48f5-aaa1-36f2873f9e4d
Duct of Wirsung is:
Parotid duct.
Common bile duct
Main Pancreatic duct
Accessory Pancreatic duct
2c
single
Ans. C. Main Pancreatic ductThe pancreatic duct, or duct of Wirsung (also, the major pancreatic duct), is a duct joining the pancreas to the common bile duct to supply pancreatic juice provided from the exocrine pancreas, which aids indigestion. The pancreatic duct joins the common bile duct just prior to the ampulla o...
Anatomy
Abdomen & Pelvis
26a88cb6-47ae-47cb-8cd5-fc7010660ed1
pseudorosettes are seen in -
Retinoblastoma
Ophthalmic nodosa
Phakolytic glaucoma
Trachoma
0a
single
Flexner wintersteiner rosettes , homer wright rosette , fleurettes and pseudorosettes are seen. Ref: ak khurana 6th edition
Ophthalmology
Tumors
54fad27e-aeec-4ddb-b0dc-4d8d411819ec
Which of the following has serous secretion?
Pancreas
Parotid gland
Sub mandibular salivary gland
Minor salivary gland
1b
single
Most animals have three major pairs of salivary glands that differ in the type of secretion they produce: parotid glands produce a serious, watery secretion. submaxillary (mandibular) glands produce a mixed serous and mucous secretion. sublingual glands secrete a saliva that is predominantly mucous in character. (Ref: ...
Physiology
General physiology
be7f0c4d-aa9a-49d0-bb1b-d97d4a646e44
Major fate of glucose 6 phosphate in tissue in a well fed state is
Conversion to glycogen
Hydrolysis of glucose
Isomerization wto fructose 6 phophate
None of the above
0a
multi
null
Biochemistry
null
b3bddc18-ca0d-4b31-84ca-0a1b8acdec58
Displacement is the defensive mechanism for (NOT REALTED)
Phobia
Depression
Persecutory delusions
Delusions of grandiosity
0a
single
In Phobia patient has fear of something which then is replaced by generalized fear of so many things.
Pharmacology
All India exam
a5d0995d-867a-4470-bdc9-2d9cb551d9c5
The most common neurologic abnormality that occurs with head injury is:
Hemiplegia
Ocular nerve palsy
Altered consciousness
Convulsion
2c
single
Ans. (c) Altered consciousness Signs of Head injury* Sudden loss of consciousness (Most common neurological abnormality)* Convulsions* Sudden dilatation of one pupil (Anisocori) - Omnious sign* Abnormal posture (Decorticate posture) - in Diffuse Axonal Injury* High ICP
Surgery
Trauma
51054785-af67-4f2e-8834-a177e8e517a5
In a pregnant female with BP 150/100 mm Hg, a protein/creatinine ratio of _______ suggests development of pre-eclampsia
>0.20
>0.30
<0.20
<0.30
1b
single
Ans. is b, i.e. >0.30Ref. Fernando Arias 4/e, p 189In patients with gestational hypertension, there are high chances (15-25%) of progressing to pre-eclampsia. Pre-eclampsia is heralded by the development of proteinuria.Proteinuria >=+2 in a random urine sample is diagnostic of pre-eclampsia in these patients. When prot...
Gynaecology & Obstetrics
Hypertensive Disorders in Pregnancy
51822a40-5942-4c90-aacb-f34711eff340
Hemoperfusion with charcoal is useful in poisoning with : -
Phenytoin.
Methanol
Ethylene glycol
All of the above
0a
multi
#NAME?
Forensic Medicine
Toxicology - 3
9d1499d1-443a-45c6-9790-c53eea13d8fe
A 3–year–old boy presents with fever; dysuria and gross hematuria. Physical examination shows a prominent suprapubic area which is dull on percussion. Urinalysis reveals red blood cells but no proteinuria. Which of the following is the most likely diagnosis –
Acute glomerulonepluitis
Urinary tract infection
Posterior urethral valves
Teratoma
2c
single
It is a case of Posterior Urethral Valve presenting with Urinary tract Infection. PUV is the most common cause of obstructive uropathy in a male child. The key to diagnosis are - Age and sex of the patient Urinary tract infection is rare in a male child, greater than one year old and less than 5 years old. Presence o...
Pediatrics
null
0a3261b6-dbfd-4a77-a14a-06069c17f087
Which of the following is seen in mania: September 2011
Low activity
Over activity
Normal activity
None of the above
1b
multi
Ans. B: Over activity Manic episode: There is an increased psychomotor activity, ranging from overactiveness and restlessness, to manic excitement where the person is 'on-the-toe-on-the-go', (i.e. involved in ceaseless activity) Bipolar disorder (BPD): Mania alone may be categorized as BPD, but depression alone is not ...
Psychiatry
null
79cce33d-5409-4126-abad-9f0ba94a6c4d
Which of the following is not true about newborn assessment
APGAR at 7 min indicates neonatal moality depression
APGAR at 1 min, indicators for neonatal resuscitation
Fetus can raoidly washout CO2 through placenta
Anaerobic metabolism causes acidemia
0a
multi
The Apgar score is based on a total score of 1 to 10. The higher the score, the better the baby is doing after bih. A score of 7, 8, or 9 is normal and is a sign that the newborn is in good health. Reference: GHAI Essential pediatrics, 8th edition
Pediatrics
New born infants
db723471-6f54-4534-ab8c-5cbd65b10d1c
ECF best value is given by
Mannitol
Inulin
D2O
Evan's blue
1b
single
ECF volume is measured using inulin which is a polysaccharide.(Ref: Textbook of physiology N Geetha 2nd edition page no.61)
Physiology
General physiology
3fba46b6-fd70-4739-a054-b5b32b243edd
Which of the following statements is true about new formula WHO–ORS?
It has Na+ ion concentration of 75 mM/L
Its glucose concentration is 75 mM/L
Its total osmolarity is 245 mOsm/L
All of the above
3d
multi
null
Pharmacology
null
784bad5e-6379-46a1-b9f8-abbd906e5566
True statement(s) regarding feeding of HIV-infected child is/are –a) Breast feeding for 4–6 months then start weaningb) Breast feeding for 1 year then start weaning c) Exclusively top feedingd) Breast feeding for 6 months & then rapid weaning
ab
bc
bd
cd
3d
multi
HIV infection can be transmitted from infected mother to fetus by breast feeding (though this is the least common mode of vertical transmission for HIV). It seems reasonable for women to substitute infant formula (top feeding) for breast milk if they are known to be HIV infected or are at risk for ongoing sexual or par...
Pediatrics
null
6b7f21d5-934e-42c5-9a2c-b0fa7f1cfa7d
Best investigation for carcinoma colon
Barium enema
Colonic biopsy
Clinical examination
Colonscopy
3d
single
null
Surgery
null
6ae2d9d8-8768-40cf-868d-378eb9f08e9b
An elderly female patient presented with hematuria and on imaging was found to have stage T2 transitional cell carcinoma of the bladder. Which of the following statements about management of her condition is true:
History of smoking is not a risk factor
Cystoscopic fulgration is the standard treatment
There is no role of chemotherapy
70% chance of requiring cystectomy in 5 years after TUR
3d
multi
Cigarette smoking is the main etiological factor and accounts for about 50% of bladder cancers. Stage T2 implies muscularis propriae invasive disease. The standard treatment for muscle invasive disease is radical cystectomy with pelvic lymphadenectomy (and not cystoscopic fulgration). Chemotherapy has a role in TCC. ...
Surgery
null
bc4da119-b151-4446-8abb-54c62f303efb
Which of the following refractory is used to counteract most of the expansion
Quartz
Cristobalite
Tridymite
Corundum
1b
single
null
Dental
null
6dffb1da-baf0-4428-80f7-5cb2da29e7e7
Pogonion is
Most inferior point on the contour of the chin
Lowest point on the syrn physeal outline
Most posterior inferior point on the angle of the mandible
Anterior most point on the contour of the chin
3d
single
null
Dental
null
7a7d903a-1a98-4d08-885b-f635f3e19f51
SARS most common in ?
Coal miners
School kids
Pregnancy
Health care workers
3d
single
Ans. is 'd' i.e., Health care workers Health care workers, especially those involved in procedures generating aerosols, accounted for 21 per cent of all cases. Maximum virus excretion from the respiratory tract occurs on about day 10 of illness and then declines. The efficiency of transmission appears to be greatest fo...
Social & Preventive Medicine
null
c764a4c5-9b9b-4f9c-9ba8-94abca2a2808
Causes of dysfunctional uterine bleeding can be:a) Uterine polypb) Fibroidc) Granulosa cell tumourd) Irregular ripening of endometriume) Irregular shedding of endometrium
ab
bc
cd
de
3d
single
DUB is defined as a state of abnormal uterine bleeding without any clinically detectable organic pelvic pathology. DUB is of 2 types:      1. Anovulatory (80%)                                       2. Ovulatory (20%) Anovulatory (80%):   • Threshold bleeding of puberty menorrhagia                                      •...
Gynaecology & Obstetrics
null
96ab4ccf-0432-458b-94b8-362beb216f80
All are characteristics of Rett syndrome Except
Microcephaly
Autistic behavior
Autosomal recessive inheritance
Peculiar wringing motion of the hands
2c
multi
The genetics of Rett syndrome has not yet been determined. Although it is thought to be a genetic syndrome, no inheritance pattern and no enzymatic deficiency or other metabolic explanation has been established for Rett syndrome. The other characteristics (autistic behavior, microcephaly, the peculiar wringing motion o...
Pediatrics
Growth and development
37f40939-4a90-41fe-b32e-f17938e9a193
Least common presentation of HCC
PUO
Mass
Jaundice
Weakness
0a
single
On rare occasions, HCC can present as a rupture with the sudden onset of abdominal pain followed by hypovolemic shock secondary to intraperitoneal bleeding Other rare presentations include hepatic vein occlusion (Budd-Chiari syndrome), obstructive jaundice, hemobilia or fever of unknown origin(PUO) Ref: Sabiston 20th e...
Anatomy
G.I.T
67506720-64c3-44a1-850c-49edaf677c0c
Cribriform plate is a pa of?
Ethmoid
Maxilla
Nasal
Frontal
0a
single
Ethmoid is a very light cuboidal bone situated in the anterior of base of cranial cavity between the two orbits; 1. Pa of medial orbital walls 2. Pa of nasal septum 3. Pa of root of orbit 4. Lateral walls of the nasal cavity Ethmoid bone comprises 1 cribriform plate 2. Perpendicular plate 3. A pair of labyrinth Ref BDC...
Anatomy
Head and neck
0aef5dc1-d011-4559-900e-7bee4a83a0b0
Definitive host is one in which the following lives -
Larvae
Asexual form
Adult form
A or B
2c
single
HOST A host is a person or other animal, including birds and ahropods that affords subsistence or lodgement to an infectious agent under natural conditions. Definitive host (primary host): A host in which parasite attains maturity or passes its sexual stage. Intermediate host(secondary host), A host in which larval or ...
Social & Preventive Medicine
Environment and health
87dcff16-12f0-46e4-bb0e-f9d3e5e688ab
Caries activity is increased in
Xerostomia
Sugar diet
Taking much carbohydrate food
None
0a
multi
null
Dental
null
4a7bef83-278a-4bea-9ddd-58fc38699f87
All the following structures develop from Mandibular arch except
Anterior belly of Digastric
Mylohyoid
Posterior belly of Digastric
Tensor Tympani
2c
multi
Posterior belly of digastric is developed from the second archMuscles of first arch (mandibular)Medial and lateral pterygoids, Masseter, Temporalis, Mylohyoid, Anterior belly of digastric, Tensor tympani, and Tensorpalati.Reference: Inderbir Singh Embryology; 10th edition; Page no: 132
Anatomy
General anatomy
c3419867-b9d6-491b-bbab-a1f720c03d0e
Which of the following has highest glycemic index:
Glucose
Sucrose
Fructose
Sorbitol
0a
single
Glycemic index (GI)- Definition -Increase in blood glucose after the test dose of a carbohydrate compared with that of an equivalent amount of glucose. The highest glycemic index is for glucose & galactose High GI maltose, trehalose isomaltose lactose Fructose and sugar alcohols have less glycemic index HFCS (High Fruc...
Biochemistry
Classification of carbohydrate