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135
a1ed2706-b900-479c-90a6-73e9fe3a73b3
Blood nerve barrier is formed by:
Perineurium
Schwann cells
Epineurium
Endoneurium
0a
single
Ref: Histology a Text and Atlas, 6th edition, Michael H. Ross, Page 376Explanation:"Together with endothelial cells of blood vessels within the fascicle, perineurial cells constitute part of the blood-nerve barrier, an important andselective diffusion barrier against entry of potentially infectious and toxic substances...
Physiology
Sex Hormones
798e154e-3279-45d8-b342-bdc264afa10c
The most commonly implicated neurotransmitter in the aetiology of schizophrenia is
Norepinephrine
Serotonin
Dopamine
GABA
2c
single
Schizophrenia is presently thought to be probably due to a functional increase of dopamine at the postsynaptic receptor, though other neurotransmitters such as serotonin (especially 5-HT2 receptors), GABA and acetylcholine are also presumably involved. Ref: A Sho Textbook of Psychiatry, Niraj Ahuja, 7th Edition, pg. no...
Psychiatry
Schizophrenia and other psychotic disorders
265167a0-dd2b-435a-b21e-6d7e56ad6403
True about estrogen production in menstural cycle?
Only by theca cells
Only by granulosa cells
Both theca and granulosa cells
None of the above
2c
multi
Ans. is 'c' i.e., Both theca and granulosa cells Ovarian follicle contains two types of cells in preovulatory phase :-i) Granulosa cells :- Secrete mainly estrogen and very minimal amount of progesterone.ii) Theca cells (interna & externa) Theca interna cells provide androgen and pregnenolone to granulosa cells to conv...
Physiology
null
b6be5ace-6f3a-426b-a11c-b9ca047f62b6
Anaesthesia of choice in renal disease – a) Atracuriumb) Cisatracuriumc) Vecuroniumd) Rocuroniume) Mivacuronium
abc
bcd
abe
acd
2c
single
Atracurium /Cisatracurium are the muscle relaxant of choice in renal diseases. Mivacurium is an alternative. Vecuronium and Rocuronium are primarily excreted in bile, therefore are safe in renal diseases. However, they are not the muscle relaxant of choice. If the question would have been framed differently, i.e. the m...
Anaesthesia
null
f3538c89-4a80-449e-803d-104c74ebf9ca
Which of the following statements about miltefosine is True?
It is used only for visceral leishmaniasis
A 4 week course produces cure rate of around 65%
It is the oral drug for treatment of kala-azar
It is safe in pregnancy
2c
multi
MILTEFOSINE - It is the first oral drug for treatment of kala azar. - 4 weeks course can produce cure rates of more than 95 percent - It can be used for visceral as well as cutaneous leishmaniasis. - It has a very long half life. - Reversible derangements of LFT and KFT have been noted. - Miltefosine is teratogenic and...
Pharmacology
Anti-Parasitic Drugs
e22676e3-ebf4-464b-8af3-ab81a4f2e4b2
Which one of the following clinical findings excludes the diagnosis of polymyositis?
Neck muscle involvement
Extraocular muscle involvement
Dysphagia
Abdominal muscle involvement
1b
single
PM don't have any of the following:rashes ,involvement of extraocular and facial muscles ,family history of neuromuscular disease,history of exposure to myotonic drugs or toxins ,endocrinopathy ,neurogenic disease,muscular dystrophy ,biochemical muscle disorder. Ocular muscles are never involved in generalized polymyos...
Medicine
C.N.S
24642e27-fed8-454e-ba83-6806eee554c1
Drugs used in the treatment of rhinoscleroma include all except:
Streptomycin
Ciprofloxacin
Tetracycline
Erythromycin
3d
multi
Drugs used for treatment of rhinoscleroma are streptomycin (1g/day), ciprofloxacin (Ig/day)or tetracycline (2g/day). Treatment is continued till clinical improvement and negative tissue cultures are obtained.
ENT
Nose and PNS
7c60f2d8-70c4-4ba8-a804-3a488993fa52
High - resolution CT of the lung is a specialized CT technique for greater detail of lung parenchyma and it utilizes -
Special lung filters
Thick collimation
Bone algorithm for image reconstruction
Large field of view
2c
single
Principles of HRCT are:-              i)  Narrow beam collimation (thin collimation)              ii)  High-frequency reconstruction algorithm, e.g. bone algorithm              iii) Small field of vision
Radiology
null
62f3a657-37d0-438c-a68a-04e31419b75e
Kayser fleischer ring is seen in -
Siderosis
Chalcosis
Open angle glaucoma
Chemical injuries
1b
single
Chalcosis- It refers to the specific changes produced by the alloy of copper in the eye. Mechanism - copper ions from the alloy are dissociated electrolytically and deposited under the membranous structures of the eye. KF ring is due to deposition of copper under peripheral pas of descemets membrane of cornea. Fleische...
Ophthalmology
Ocular trauma
48672729-5df7-4746-a0eb-97021ad980a0
Who gave the model for demineralization & remineralization of white spot lesion?
Miller
Moreno
Martin
Massler
1b
single
The physiochemical process of white spot lesions was difficult to understand until the Moreno model was described. In this model, acids formed by cariogenic bacteria dissolve the surface as well as subsurface enamel. The calcium and phosphate ions from the subsurface dissolution diffuse downwards toward the surface and...
Dental
null
8e17ad95-a764-4105-ba2b-0d1b804ace27
A 70 year old alcoholic presents with abdominal pain, lump in the RUQ and weight loss. No history of upper or lower Gl symptoms. USG shows 10 x 10 cm mass in the right lobe of liver. Which serum marker will be helpful in diagnosis?
Serum calcitonin
CA19-9
Alkaline phosphatase
Alpha-fetoprotein
3d
single
Answer: d) Alpha-fetoprotein (ROBBINS 9th ED, P-337)A 70 year old chronic alcoholic with abdominal pain, weight loss & lump in the RUQ suggests liver cancer. AFP is the tumor marker which is raised in liver cancerTUMOR MARKERSMarkersAssociated cancersNon neoplastic conditionsHuman chorionic gonadotropinTrophoblastic tu...
Pathology
Liver & Biliary Tract
e8b8e80b-cad8-4d2d-a468-93818549b3af
Goodpasture's syndrome is characterized by -
Necrotising hemorrhagic interstitial pneumonitis
Alveolitis
Patchy consolidation
Pulmonary edema
0a
single
Goodpasture syndrome Goodpasture syndrome is a rare condition characterized by the rapid destruction of the kidney and diffuse pulmonary hemorrhage. It is an autoimmune disease characterized by the presence of circulating autoantibodies targeted against basement membrane of lung and kidney. These antibodies are direct...
Pathology
null
2dc41761-4fc2-4a46-86ff-36bfa0d1a0d8
Snake venom acts by?
Classical pathway
Alternate pathway
Both
None
2c
multi
Both REF: Manson's tropical diseases By Gordon C. Cook, Patrick Manson, Alimuddin Zumla Page 566, Elapid and Colubrid venoms activate complement alternative pathway (cobra venom factor), Russell's viper classical pathway Southern pacific rattle snake inactivates both alternate and classical pathway
Forensic Medicine
null
a1c5b748-7a00-46b3-a547-e828cb31cc7f
NOT used as a post - coital contraception :
Danazol
Ethinyl estradiol
Levonorgesterel
Misoprostol
3d
single
Ans. is d i.e. Misoprostol Friends, here the answer of choice is Misoprostol as it is never used for Emergency contraception (though according to Shaw it can be used) whereas Danazol can be used but is less desirable than other methods because of its less efficacy.
Gynaecology & Obstetrics
null
99be6250-8f74-4521-b450-3b4cade34103
Minimal interval between two live vaccines administered by the oral route is
Any time
2 weeks
4 weeks
3 months
0a
single
Live vaccines administered by the oral route (Oral Polio vaccine-OPV; oral typhoid and Rota virus) are not believed to interfere with each other if not given simultaneously. These vaccines may be given at any time before or after each other. Live parenteral (injected) vaccines and live intranasal influenza vaccine shou...
Pediatrics
All India exam
1c7376a9-762a-4369-8f35-65e782848632
in the condition above the patients presents with ?
hyperkalemia
metabolic alkalosis + paradoxical renal aciduria
hypernatremia + hypochloremia
metabolicacidosis
1b
multi
image is : gastric outlet obstruction patient presents with vomiting/ball rolling hypokalemia,hyponatremia, hypochloremia metabolic alkalosis + paradoxical renal aciduria treatment: iv fluids ,NS + kcl supplement ref : bailey and love 27th ed
Surgery
All India exam
e3a3915d-5644-4f79-b5e7-4b9954601a93
Abnormal cellular growth may result in either a decrease or an increase in the mass of the involved tissue. Both hyperplasia and hyperophy are found in:
Pregnancy uterus
Cardiac muscle in cardiomegaly
Skeletal muscle in athelete
Breast development in lactation
0a
multi
Uterine myometrial hyperplasia and hyperophy are seen during pregnancy (hormone-induced). Hyperophy results from increased amounts of cytoplasm and cytoplasmic organelles in cells.Hyperplasia results when cells of a tissue are stimulated to undergo mitotic division, thereby increasing the number of cells. Ref: Chandras...
Pathology
null
05f2285c-f9d6-40df-84ef-7800cccc5e5a
A 2 year old child without fever develops bone pain, vomiting and features of increased intracranial pressure following excessive medication. The drug most likely to be responsible for this is –
Vitamin A
Phenothiazine
Phenytoin
Vitamin D
0a
single
It is a case of pseudotumor cerebri.
Pediatrics
null
b99af515-e985-433f-945a-621e978ed8c6
FG, FFG, FFFG....used to describe: (PGI May 2011)
Primer
Cartridge
Black gunpowder
Wadding
2c
single
Ans: C (Black gun..) FG, FFG, FFFG.... are used to describe the size of grains of black gunpowder.Gunpowder used in FirearmsBlack PowderQ# It consists of Potassium nitrate 75%, Charcoal 15% & Suiph ur 10% (Pnemonic - PCS in decreasing percentage)# It is designated as FG, FFG, FFFG, etc., depending on size of the grains...
Forensic Medicine
Injuries by Firearms
ad0c84e1-9a31-412c-ba11-cb5c28623c6d
The disposable plastic syringes are best sterilized by-
Formaldehyde
Ethylene oxide
Hexachloride
UV radiation
1b
single
null
Microbiology
null
92b533e6-8806-42ea-afc0-577cdf047c5a
Identification features of oesophagus are all except
Submucosal glands are present
Lined by Stratified ciliated columnar epithelium
Upper 1/3rd skeletal muscle; Middle 1/3rd mixed fibres and Lower 1/3rd smooth muscle fibres
Tunica adventitia is present
1b
multi
Oesophagus is lined by Stratified squamous non-keratinized epithelium.The oesophagus is covered by an adventitia until it pierces the diaphragm, after which it is covered by a serosa.Oesophagus and duodenum have submucosal glandsThe muscularis externa of the upper third of the oesophagus has mostly skeletal muscle, the...
Anatomy
General anatomy
4562d98c-a3e7-4c8c-b54b-4e3cd19744a5
Which of the following is associated with anti-glomerulal basement membrane antibody ?
IgA nephropathy
Membranous glomerulonephritis
Goodpasture's syndrome
Mernbrano-proliferative glomerulonephritis
2c
single
Repeated question
Pathology
Urinary tract
8f6a70fe-11ed-4bfc-b595-375ea858af94
Digitalis produces which of the following changes in ECG ?
Tall T waves
ST segment elevation
Prolonged QT interval
Prolonged PR interval
3d
multi
Ans. is 'd' i.e., Prolonged PR interval o There are some characteristic ECG changes by digitalis use, some of which occur at therapeutic concentration and some occurs at toxic level :1. At therapeutic levelo Prolongation of PR intervalo Scooping of ST segment - Also known as digitalis wave or dig sag there is down slop...
Pharmacology
Digitalis
7638bbe1-9ded-44df-8a27-3c49428f72d4
A rnultilocular cyst of the jaw is more likely:
Dental cyst.
Dentigerous cyst.
Keratocyst
Simple bone cyst.
2c
single
null
Pathology
null
6cdc4d5a-9236-4b5b-a7e6-4c923a22b004
All are true regarding SIADH, except -
Increased level of ADH (AHMS Nov 93)
Urine hvpoosmolar
Hyponatremia
Adequate hydration status
1b
multi
Ans. is 'b' i.e., Urine hypoosmolar Cardinal features of SIADH include:o Hyponatremia (dilutional hyponatremia with Na+ < 135 m mold).o Decreased plasma osmolality (<280 m osm/kg with inappropriately increased urine osmolality > 150 m osm).o High urine sodium (over 20 meq/l).o Low blood urea Nitrogen <10 mg/L.o Hypouri...
Medicine
Endocrinology
b9fbc85e-59d5-4b42-8870-45a8f5eba164
Medial calcification is seen in -
Atherosclerosis
Arteriolosclerosis
Monckeberg's sclerosis
Dissecting aneurysm
2c
single
First, see types of arteries Based on their size and structural features, arteries are divided into three types. 1. Large or Elastic arteries Aorta Its large branches, eg. - Innominate, Subclavian, common carotid, iliac. Pulmonary arteries. 2. Medium sized or muscular arteries Small branches of aorta → Coronary, Re...
Pathology
null
bd2a25ae-44da-4f51-9b0c-e581ae6c5309
Which of the following is the treatment of choice for cryptococcal meningitis?
Fluconazole
Itraconazole
Flucytosine
Amphotericin B
3d
single
Amphotericin B (AMB): Antifungal spectrum AMB is active against a wide range of yeasts and fungi-Candida albicans, Histoplasma capsulatum, Cryptococcus neoformans, Blastomyces dermatitidis, Coccidioides immitis, Torulopsis, Rhodotorula, Aspergillus, Sporothrix, etc. Dermatophytes are inhibited in vitro, but concentrati...
Pharmacology
Chemotherapy
e2957ada-da8f-47bb-a74f-544a504e07db
F body is
Y chromatin
X chromatin
Chromosome 1
Chromosome 21
0a
single
Ans. (a) Y chromatin(Ref: Emery Genetics)Quinacrine, a fluorescence dye, binds strongly to the Y chromosome forming a bright fluorescent spot (F body). This is clearly visible in stained interphase cells from various tissues from the human male and in mature spermatozoa
Pathology
Genetics
6dd1a6ba-f791-4b36-b877-91bd0f29fcd0
A 28-year-old woman comes for treatment of hirsutism. She is obese and has facial acne and hirsutism on her face. Serum LH level is 32 mIU/mL and FSH is 9 mIU/mL. Androstenedione and testosterone levels are mildly elevated, but serum DHEAS is normal. The patient does not wish to conceive at this time. Which of the foll...
Oral contraceptives pills
Coicosteroids
GnRH analogue
Wedge resection of ovary
0a
single
This patient has PCOS, diagnosed by Clinical picture- Obese, Facial acne and Hirsutism Abnormally High LH-to-FSH ratio, and increased androgens but Normal DHEAS(excludes Adrenal sources of Hyperandrogenism) To treat Hirsutism associated with PCOS:- OC pills suppress hair growth, act by directly suppressing ovarian ster...
Gynaecology & Obstetrics
Polycystic Ovarian Syndrome
4eb2a7f5-0717-4064-8282-d1d2b9e27ebb
The internal anal sphincter is formed by:
Puborectalis
Circular muscle fibers
Longitudinal muscle fibers
Deep peroneal muscle
1b
single
Ans: B (Longitudinal muscle fibers) Ref: Grays Anatomy 40th editionExplanation:Internal anal sphincterThe internal anal sphincter is a well-defined ring of obliquely orientated smooth muscle fibers that is continuous with the circular muscle of the rectum, and which terminates at the junction of the superficial and sub...
Unknown
null
28bfc6b4-c7ae-46ce-90c1-e3fe755780a2
Health education is the responsibility of
Health educationalist
Doctor
Paramedical staff
Every health worker
3d
single
null
Social & Preventive Medicine
null
be13bbb0-327e-4ee4-9146-4dc06b187401
What is the artery labeled with black arrow in the given diagram?
Posterior communicating artery
Antirior Inferior Cerebellar artery
Superior Cerebellar artery
Basilar artery
0a
single
Ans- A . Ref- The central nervous system, like any system of the body, requires constant oxygenation and nourishment. The brain has a particularly high oxygen demand - at rest it represents one fifth of the body's total oxygen consumption. It is also very sensitive to oxygen deprivation, with ischemic cell death result...
Anatomy
Meninges & Blood Vessels of the Brain
a0ea3064-70fe-458f-89fd-94d152772a67
All of the following statements about cerebellar astrocytomas in paediatric age group is true, EXCEPT:
These are usually Low grade tumors
These tumors have a good prognosis
These are more commonly seen in the 1st and 2nd decades
These tumours are more common in females
3d
multi
Cerebellar Astrocytomas are equally common in males and females and it is a low grade tumor, classified as a WHO grade I tumor. It is most commonly develop during the first two decades of life. Ref: Nelson 18th Edition, Page 2130, 2131; Harrison 17th Edition, Page 2602, 2603, 2604
Pediatrics
null
11933f84-5f8a-41f0-976a-71da9252c62f
Which of the following is the most likely diagnosis of the given below condition?
Cushing's syndrome
Peutz-Jegher syndrome
Scleroderma
Chronic Clofazimin usage
1b
single
Peutz-Jegher syndrome is characterized  by acral lentigenes (hyperpigmented macules on face and buccal mucosa) with hamartomatous polyps in gastrointestinal tract.
Dental
null
5d76e00f-d836-4379-843a-b2a902ee1245
Systemic adverse effects of long term inhaled steroids are evident only at doses more than ?
200 mcg/day
400 mcg/day
600 mcg/day
800 mcg/day
2c
single
Ans. is 'c' i.e., 600 mcg/day. lRef: KDT Vhle p. 230)Systemic effects of long-term inhaled glucocoicoids are clinically relevant only at doses > 600 mcg/day.The significant ones are-mood changes, osteoporosis, growth retardation in children, bruising, petechiae, hyperglycaemia and pituitary-adrenal suppression; several...
Pharmacology
null
b6770f37-a239-43cb-987f-e45b81d2fb9a
Which of the following is not a feature of Crohn's disease?
Spiking fever
Enterovesical fistula/ Fecaluria
Perianal tags
Proctitis
3d
single
Crohn's disease - Intraabdominal abscess causing spiking fever (High grade with chills & rigor) Hallmark - Fistula formation (Peri-anal fistula) - Fecaluria (Communication between the gut and Bladder; stool will come in urine) -Rectum is spared -MC pa involve is T. ileum -Proctitis- usually a feature of UC. MC pa invol...
Medicine
Inflammatory Bowel Disease
a02aef9e-52fe-4e18-9aff-3b1a6918b2a0
All of the following statements about atrial myxomas are true, except:
Most common site is left atrium
More common in females
Tumor plop in systole
Raynaud phenomenon
2c
multi
* Tumour plop sound is a low pitch sound heard in diastole when the tumour impacts against the opening mitral valve. * Myxomas- present with peripheral or pulmonary emboli or with constitutional signs and symptoms- fever, weight loss, cachexia, Raynaud's phenomenon, hypergammaglobulinemia, anemia, polycythemia, leukocy...
Medicine
Murmurs
6e26126a-be71-4d34-8e98-36d5ecbe86f8
Which of the following adaptations will be apt to increase the work capacity at high altitude
Increasing workload, decreasing duration of exercise
Increasing workload, increasing duration of exercise
Decreasing workload, increasing duration of exercise
Decreasing workload, decreasing duration of exercise
2c
single
If we increase the workload, more oxygen will be required. At high altitudes oxygen is low. So we need to decrease the workload. At the same time, to increase the work capacity, we need to increase the duration of exercise without increasing the load.
Physiology
null
cb3d6478-1eb7-4599-82d0-b05d8cb5bf85
A 55 year old female patient has carcinoma ovary with bilateral involvement with ascitic fluid in the abdomen. The stage is:
II
III
IV
IC
3d
single
null
Gynaecology & Obstetrics
null
f30b0733-99d0-42a7-ac4f-dd0564bdcff9
In which of the following conditions ovaries function normally
Turner s syndrome
Mayer rokitansky kuster hauser
Androgen insensitivity syndrome
Sweyer's syndrome
1b
multi
Turners syndrome has streak ovaries AIS is a genotypic male 46 XY with testes and a female phenotype (insensitivity to androgens produced by testes) Swyers syndrome is a 46 XY female where the testes are non-functional and hence a default female form is made MRKH is a woman with normal ovaries but no Uterus.
Gynaecology & Obstetrics
Mullerian Abnormalities
550214d2-e68e-4631-aad8-380bc52ffb9f
True about electroretinogram?
a wave is a positive wave
a wave arises from pigment epithelium
b wave arises from rods and cones
c wave is a positive wave
3d
multi
ELECTRORETINOGRAPHY( ERG ): Measures the changes in the resting potential of the eye, induced by the stimulation of the eye with a light stimulus. Components : *'a' wave - Negative wave, representing the activity of Rods and Cones *'b' wave - Positive wave, representing the activity of inner retinal layers. *'c' wave -...
Ophthalmology
Optics and refraction
8eb295b6-dd0a-4106-8255-d1174793e2c9
Which of the following statement is true about colostrum? 1. Secreted after 11 days of childbih 2. Rich in Immunoglobulin 3. Contains more protein than milk 4. Contains less fat than milk 5. Daily secretion is about 10ml/day
1,2,3 False & 4,5 True
2,3,4 True & 1,5 False
2,3,4 False & 1,5 True
1,2,4 True & 3,5 False
1b
multi
Colostrum is very rich in proteins, vitamin A and sodium chloride, but contains lower amounts of carbohydrates, lipids, and potassium than normal milk. Colostrum contains immunoglobulins such as IgA, IgG, and IgM.
Gynaecology & Obstetrics
null
6fb940fa-195e-4e4c-96b6-cba99d416a46
The type of suture represented by sagittal suture of the cranial vault is
Serrate
Denticulate
Squamous
Plane
0a
single
The joints in the skull are mostly sutures. Various types of sutures in the skull are, Plane suture - Eg. Internasal suture, mid palatal suture. Serrated suture - Eg. Sagittal and coronal suture (interparietal suture). Denticulate suture - Tooth like projections. Eg. Lambdoid suture. Squamous suture - Eg. Parieto-temp...
Anatomy
null
95985c68-1219-4f3b-aea4-a5a0727f4a36
Arrange the following in sequence occurring in fed state 1. Insulin 2. GLUT-2 3. Uptake of glucose by skeletal muscles 4. GLUT-4
2-1-3-4
4-2-3-1
2-1-4-3
1-3-4-2
2c
single
During Fed state GLUT-2 = Insulin = GLUT-4 = Uptake of glucose by skeletal muscles
Biochemistry
Fuel in Fed, Fasting and Starvation
418f15eb-c457-4565-a5fa-25fd17ec52d2
Dissemination of toxoplasma is :
Blood
Faeces
Urine
None of the above
0a
multi
Blood
Microbiology
null
a1ca185d-b981-4344-9c5f-ae2d7ce130f4
Why is Covid-19 a major global concern despite the propey of influenza to spread faster than Covid-19 ?
Median incubation period is more in influenza
Reproductive number for covid-19 is 2-2.5
Serial interval is 5-6 days in influenza
Reproductive number for Influenza is more
1b
single
Influenza Covid-19 Median incubation period 2 days 5.5 days Serial interval 3 days 5-6 days Moality 0.1% 3% Though Influenza spreads faster than covid 19 but moality and reproductive number is higher for covid-19 due to which it is a disease of global concern . Reproductive number- No. of secondary infections generated...
Medicine
viral infection
ad0ab14c-d7a1-48ca-a6c7-15ea24c5dc3c
Chloroquine acts on -
Merozoites
Blood schizont
Tissue schiont
Gametocytes
1b
single
Ans. is 'b' i.e., Blood schizont o Chloroquine is highly effective blood schizontocide.
Pharmacology
null
323cebdc-1b1a-4fa0-840a-f45c883ee0f5
About infective endocarditis (IE), the following is false:
Duke’s criteria is used to diagnose IE
Libman Sack’s endocarditis is seen in Systemic Lupus Erythematosus
Osler’s nodes are seen at the occiput and pressure bearing areas
Janeway lesions are present on the skin
2c
multi
Osler's Nodes are seen in the pulp of fingers.
Medicine
null
34abac41-f6c6-4080-a8da-aca7d8ba86e3
Senescent RBC&;s are mainly attcked in -
Vivax malaria
Ovale malaria
Falciparum malaria
Quaan
3d
single
Plasmodium malariae causes quaan malaria, in which febrile paroxysms occur every fouh day, with 72 hours' interval between the bouts. The disease is generally mild, but is notorious for its long persistence in circulation in undetectable levels, for 50 years or more.The sporozoites are relatively thick. Pre-erythrocyti...
Microbiology
parasitology
4580f799-4135-4584-9148-396a75a554b9
An increased incidence of pancreatitis is associated with all of the following except?
Alcoholism
Cholelithiasis
Chlorothiazide therapy
Hypertension
3d
multi
Ans- (d) HypertensionRef: Robbings pathology 9th ed. /884-86* Acute pancreatitis is seen chiefly in males after age 40 and often associated with obesity and alcoholism.* In about 50 percent of the cases, gallstones are also present.* Pancreatitis occurs in about 10 percent of cases of hyperparathyroidism* Long term Thi...
Pathology
G.I.T.
0fff6189-1b16-4193-8f91-1809e1022f0f
Distance of distant direct ophthalmoscopy is: March 2013 (a, b, c, d, g, h)
22 cm
50 cm
75 cm
100 cm
0a
single
Ans. A i.e. 22 cm Distant direct ophthalmoscopy Used to get a preliminary idea about the status of the ocular media and fundu This should be done routinely before doing a direct ophthalmoscopy Equipment needed - self illuminated ophthalmoscope or plane mirror with a hole in centre Procedure Should be performed in a sem...
Ophthalmology
null
97588d92-bd0a-4cb4-b493-cab9241cc45f
Mannitol decreases the intraocular pressure by ?
Withdrawing water from vitreous
Increasing uveoscleral outflow
Increasing aqueous through trabecular meshwork
Inhibiting the enzyme carbonic anhydrase in the ciliary body
0a
single
Ans. is 'a' i.e., Withdrawing water from vitreous By osmotic action mannitol encourages movement of water from aqueous humour --> decrease. Mannitol is used in angle closure (narrow angle, acute congestive) glaucoma. Treatment of acute congestive glaucoma o Definitive therapy is surgery (laser iridotomy) Drugs are used...
Pharmacology
null
60f2fd8e-eb69-45e5-8e13-4c1b265eb69d
Time sector scanning of neonates is preferred for the following reason ?
Open fontanelles
Inexpensive
Children more co-operative
Better resolution
0a
single
Time sector scanning of neonates is preferred because of the practical reason the open fontanelle serve as acoustic windows. Best results are obtained with a high-frequency phased array transducer (5-8 MHz) with a small footprint probe. Additional information : Neurosonography stas with gray-scale imaging performed the...
Radiology
Fundamentals in Radiology
39931b13-b8de-4a91-9ad0-69a7c697d54f
Which of the following is a feature of congenital glaucoma?
Angle closure glaucoma
Open angle glaucoma
Trabeculodysgenesis
Inflammatory glaucoma
2c
single
Trabeculodysgenesis is the main pathogenesis for congenital glaucoma. Pathogenesis of Congenital Glaucoma Pathogenesis: Abnormal development of angle (trabeculodysgenesis) (Berkens Membrane). Flat iris inseion. Haab's stria : Horizontal Stria present in glaucoma. - Classical triad of lacrimation, photophobia & blepharo...
Ophthalmology
Glaucoma
c91a9100-38ca-47fd-a41e-94e7a5c60293
Transovarian transmission of infection occurs in -
Fleas
Ticks
Mosquitoes
Sandfly
1b
single
Ticks transmit disease by biting (larva and nymph also by biting) - Trans-stadially Experiments in ticks have shown trans-ovarian transmission of infection through successive generations. REF: PARK'S TEXTBOOK OF PREVENTIVE AND SOCIAL MEDICINE, 25TH EDITION, PG NO. 840
Social & Preventive Medicine
Environment and health
981d303b-a085-48e6-b354-313f65da4ca7
Ramu presents with recurrent attacks of cholelithiasis, USG examination shows dilated CBD of 1 cm. The next line of management is
ERCP
PTC
Cholecystostomy
Intravenous cholangiogram
0a
single
ERCP Endoscopic clearance of CBD stones can avoid the need for an open operation if expeise in laparoscopic common bile duct exploration is not available Indications of preoperative ERCP Patients with worsening cholangitis Ampullaru stone impaction Biliary pancreatitis Cirrhosis Contraindications of endoscopic sphincte...
Anatomy
G.I.T
1adabc58-0183-40ab-868a-b6c58d92aaec
Philadelphia chromosome is an example of -
Balanced translocation
Deletion
Non-dysjunction
Duplication
0a
single
null
Pathology
null
c3d8e2d3-601f-4600-9040-1861413353dc
All of the following are employed to evaluate a case of heterophoria except:
Maddox-rod test
Alternate cover test
Measurement of fusional reserve
Measurement of near point of convergence
1b
multi
Ans. Alternate cover test
Ophthalmology
null
e5e50625-979e-49bb-80b6-16b36181be5b
Which complex of ETC reacts directly with O2?
I
II
III
IV
3d
single
Complex IV: Cyt-c Oxidase The system functions: * As proton pump * Catalyses transfer of electrons to molecular O2 to form H2O. This is the terminal component of ETC. It catalyses the transfer of electrons from Cyt-c to molecular O2 Cyt-a, Cu++ ions and Cyt-a3.Ref: MN Chatterjea Textbook of Medical Biochemistry, 8th ed...
Biochemistry
Respiratory chain
ac3b92d2-4bd5-43c3-a99c-a2bd848854a2
The most impoant single function of World Health Organization is?
Prevention and control of specific diseases
Development of comprehensive health services
Health literature & Information
Biomedical research
1b
single
WHO : Established in 1945. Constitution came into force on 7th April 1948. Hence, 7th April is WORLD HEALTH DAY. Head quaers is located in GENEVA. WHD 2018,2019 Theme is Universal health coverage. WHO's most impoant single function is to promote and suppo national health policy development and the development of compre...
Social & Preventive Medicine
International health agencies
3296d685-2c76-43e0-89c5-cdabe0d73558
Pituitary secretes all hormones except ?
GH
Prolactin
Oxytocin
Thyroxine
3d
multi
Ans. is 'd' i.e., Thyroxine
Unknown
null
6f3c1803-0b17-419d-9f29-feb894f22874
The least radiosensitive tissue is:
Nervous tissue
Bone
Kidney
Thyroid
0a
single
Ans. Nervous tissue
Radiology
null
9b2e70e7-0a88-4b1c-a685-ec6b90479c08
Which of the following is determined by measuring sciatic notch index in a skeleton?
Determination of age
Identification of sex
Determination of race
Cause of death
1b
single
Sciatic notch index is a trait used for differentiating sex by measuring sciatic notch. Formula is, Sciatic notch index = (width of sciatic notch/depth of sciatic notch) * 100 It is normally 4-5 in males and 5-6 in females Ref: Essentials of Forensic Medicine and Toxicology by Narayan Reddy, 27th edition, Page 56.
Forensic Medicine
null
cf08c92d-9e95-40b4-9b60-be8e4133d2c4
A two year old male child was given 8 days of cefaclor of a 10 days course. The child develops low grade fever, malaise lymphadenopathy, irritability, generalized erythematous rash which are mildly pruritic. Most probable diagnosis is
Kawasaki disease
Paially treated meningitis
Infectious mononucleosis
Type 3 hypersensitivity
3d
multi
Type 3 hypersensitivity (Repeat)
Surgery
null
42b4b80b-41a7-4bf9-920c-770c85df12e3
Not involved in damage to cerebellum:March 2010
Posture
Equilibrium
Asthenia
Tone
2c
single
Ans. C: AstheniaSigns of Cerebellar DisordersAtaxia, Reeling, wide-based gait- decomposition of movements, Inability to correctly sequence fine, coordinated actsDysahria-Inability to aiculate words correctly, with slurring and inappropriate phrasingDysdiadochokinesia-Inability to perform rapid alternating movementsDysm...
Anatomy
null
580d99ef-2c6f-44af-b9c8-ce96c9b84c27
Game keepers thumb is -
Thumb metacarpophalangeal joint ulnar collateral ligament rupture
Thumb metacarpophalangeal joint radial collateral ligament rupture
Thumb interphalangeal joint ulnar collateral ligament rupture
Thumb interphalangeal joint radial collateral ligament rupture
0a
single
Ans. is 'a' i.e., Thumb metacarpophalangeal joint ulnar collateral ligament ruptureo Injury to the thumb metacarpophalangeal joint ulnar collateral ligament is commonly referred to as gamekeeper thumb orskierfs thumb, although the original "gamekeeper" description (Campbell, 1955) referred to an attritional ulnar colla...
Orthopaedics
Injuries of the Wrist
5b9a5111-52cd-44ba-bd87-41c60ba0442d
Right esotropia is evident with ?
Left lateral rectus paralysis
Right lateral rectus paralysis
Left medial rectus paralysis
Right medial rectus paralysis
0a
single
Ans. is 'a' i.e., Left lateral rectus paralysis
Ophthalmology
null
e212ab04-3a55-4284-8023-2ee77647ff8e
Candida is most often implicated in causation -(
Conjunctivitis
Tinea capitis
Dese rheumatism
Thrush
3d
single
Ans. is 'd' i.e., Thrush
Microbiology
null
e8c4a4c8-8ce5-4dd9-bbd5-d61de966aaa9
Oral pills may prevent the development of: March 2011
Carcinoma breast
Ovarian malignancy
Submucus fibroid
All of the above
1b
multi
Ans. B: Ovarian malignancy Combined oral pills reduce the incidence of functional ovarian cysts (50%) and ovarian and uterine malignancy The incidence of ovarian cancer is reduced by 40% OCP: They are contraceptive agent of choice in: - Newly married - Post aboal - Post paum non-lactating OCP of choice in lactating mot...
Gynaecology & Obstetrics
null
0a9c1b39-d2b6-442b-ab22-b9b8b5994052
Sorghum contains excess of
Lycine
Arginine
Leucine
Histidine
2c
single
Ans. is 'c' i.e., Leucine o Jowar (Sorghum) contains excess of leucine which can cause niacine deficiency and pellagra.
Social & Preventive Medicine
null
153a3722-ab45-4240-943f-203bd93b68de
Transport of molecules in simple diffusion is not determined by:
ATP usage
Size of molecule
Lipid solubility
Number of channels
0a
single
Ref: Pal GK. Transport across Cel! membrane. In: Textbook of medical physiology. 2""' ed. Abuja publishing house. 2011: 4: 32,33.Explanation:Permeability of substances across the membrane is decided by1. Lipid - solubility2. Molecular size3. Charge of the molecule4. Temperature5. Distribution of channels in the membran...
Physiology
Nervous System
0051af9f-8cc4-4dae-a5b0-937e2ff9da3c
Campbell line is seen in X-ray of following projection
Transcranial
Transorbital
Transpharyngeal
Occipitomental
3d
single
null
Surgery
null
ea090ecc-a122-4016-927f-71c7205c3450
A wave in JVP is due to-
Atrial contraction
Ventricular filling
Atrial filling
Bulging of tricuspid valve in right atrium
0a
single
Ans. is 'a' i.e., Atrial contraction JUGULAR VENOUS PULSEa waveIt is the positive presystolic wave produced by right atrial contraction.x descenta wave is followed by the negative systolic wave the x ' descent. The x descent is produced due to atrial relaxation. The atrial relaxation is produced as a result of ventricu...
Physiology
Heart, Circulation, and Blood
f606b723-bf31-4390-a1e7-c95d86c0e0c6
A patient after giving inhalational anaestheia developed fulminant hepatitis, patient was exposed to same drug previously. Which is the drug
Halothane
N20
Enflurane
Isoflurane
0a
single
The first modern halogenated volatile anesthetic, halothane, was introduced in 1955. Clinical exposure to halothane is associated with two distinct types of hepatic injury. Subclinical hepatotoxicity occurs in 20% of adults who receive halothane. It is characterized by mild postoperative elevations in alanine aminotran...
Anaesthesia
General anaesthesia
0190a5fb-0001-4a33-8c3d-8871f973d640
In which case lymph nodes are resected prophylactically -
Embryonal Rhabdomyosarcoma
Liposarcoma
Fibrosarcoma
Neurofibroma
0a
multi
Ans is 'a' ie Embryonal Rhabdomyosarcoma Soft tissue sarcomas metastasises through blood to lung (MC) & liver but lymphatic metastasis is very rare. Still some sarcomas metastasize to lymph nodes. Prophylactic resection is required in them along with resection of the tumor. "Rhabdomyosarcoma a tumor of striated muscle,...
Surgery
null
cfef5f66-0d0e-4d7d-83b6-cee52c15910a
Which of the following features indicates the presence of heart disease in pregnancy and which is not seen in normal pregnancy?
Exertional dyspnea
Distended neck veins
Systemic hypotension
Pedal edema
1b
single
Ans. is b, i.e. Distended neck veinsRef. Williams Obs. 22/e, p 1019, 23/e, p 960, Dutta Obs. 7/e, p 275Many of the physiological adaptations of normal pregnancy and physical findings resemble heart disease symptoms and signs, making the diagnosis of heart disease more difficult.For example, in normal pregnancy, functio...
Gynaecology & Obstetrics
Medical & Surgical Illness Complication Pregnancy
0a4b5d68-35b7-4ec4-abf7-88635517fc04
Early movement for surgery following ankylosis is
Harmful
Desirable
Unimportant
Indicated only when ankylosis is one sided
1b
single
null
Surgery
null
00194855-6308-40eb-84cb-eb9399229b02
Which of the following is preferred in treating opioid induced constipation
Linaclotide
Lubipristone
Alvimopan
Prucalopride
2c
single
Alvimopan is a peripheral opioid antagonist used against opioid induced constipation.
Pharmacology
null
a065a49e-e112-417c-ae77-ae228b1ff9fb
Distance of distant direct ophthalmoscopy:
25 cms
50 cms
75 cms
100 cms
0a
single
Distant Direct Ophthalmoscopy Distance at which DDO performed is 25cm done with direct ophthalmoscope. contains light source viewing window. Normally red glow seen Interpretations Red glow= healthy retina Grey glow = Retinal Detachment No glow = vitreous haemorrhage Black spot in centre = cataract or corneal opacity GO...
Ophthalmology
Optics and Errors of Refraction
938eb4c6-bcfe-4103-83e3-554508dd0b7e
For knowing the acute adverse effects of a drug, the drug micro doses should be tested on:
Two different species
On rabbit, one rodent
Two rabbits
Two rodents
0a
single
Ans. (a) Two different speciesType of TestApproachAcute toxicityDefined as dose that is lethal in approximately 50% of animals and is maximum tolerated dose.It requires usually two species, two routes, single dose.Subacute toxicityIt requires three doses and two species. 4 weeks to 3 months may be necessary prior to cl...
Pharmacology
Clinical Trials
1d11bdbb-06a3-4c9d-95fd-89b964b591aa
A patient undergoing surgery suddenly develops hypotension. The monitor shows that the end tidal CO2 has decreased abruptly by 155mm Hg. What is the probable diagnosis?
Hypothermia
Pulmonary embolism
Massive fluid deficit
Myocardial depression due to anaesthetic agent
1b
single
Ans. is 'b' i.e. pulmonary embolism Ref: Miller's anesthesia 5th/e p1276First what is end tidal CO2The air exhaled during normal respiration initially consists of the dead space. Then a mixture of dead space air plus alveolar air comes out. The air coming out at the end consists purely of alveolar air.Measurement of co...
Surgery
Heart & Pericardium
8eb0eb03-69ac-42b8-8627-c3be71dae47d
A new born baby with acute respiratory distress on day 1. X Ray chest PA view showed neumerous gas luscencies in entire left hemithorax, most likely diagnosis is
Congenital lobar Emphysema
Pneumatocoel hernia
Congenital diaphragmatic hernia
Congenital lung cyst
2c
single
C i.e. Congenital diaphragmatic hernia Left sided & whole lung involvementQ points towards diagnosis of Congenital diaphragmatic hernia, Cong. cystic .adenomatoid malformation (CCAM) and Congenital lobar emphysema all can present with multicystic Contralateral mediastinal shift & respiratory distress.
Radiology
null
e438d2da-1b4e-4ccd-acd2-ce913579c7bf
Best marker for GIST is
CD117
DOG 1
CD 34
CD 43
0a
single
Diagnostic markers GISTs and cajal cells express c-KIT (also known as CD117) and CD34. Most useful diagnostic marker is c-KIT and immunohistochemically detected in 95% of gastric GISTs GENERAL AND SYSTEMIC PATHOLOGY RAMDAS NAYAK FIRST EDITION PAGE 390
Pathology
G.I.T
ef2e5ddd-b4c8-4cd7-bf08-331d907c7d6e
Main risk in fracture Scaphoid is:
Non union
Malunion
Delayed union
Avascular necrosis
3d
single
D i.e. Avascular necrosis
Surgery
null
618c87f7-7a3d-4dd1-88fb-b2ec732fbc78
Alkaline phosphatase contains
Cobalt
Zinc
Iron
Copper
1b
single
ALP is a nonspecific enzyme which hydrolyzes aliphatic, aromatic or heterocyclic compounds. the pH optimum for the enzyme reaction is between 9 and 10.it is activated by magnesium and manganese. zinc is a constituent ion of ALP.Ref: DM Vasudevan Biochemistry, page no: 305
Biochemistry
Enzymes
a85a15ac-6e1e-49f2-8868-3897d5ff6606
True about Merkel cells
Slow adapting Touch receptors
Located in Stratum Basale
Derived from Ectoderm
All of the above
3d
multi
Merkel cells They are slow-adapting mechanoreceptors found in fingeips, lips, oral cavity, and hair follicle. 1) Found in stratum basale; communicate with neurons 2) CK20+ in perinuclear dot pattern sensitive/ specific for Merkel cells; also (+) for neurofilaments, S100, synaptophysin, chromogranin A, vasoactive intest...
Dental
Anatomy of skin
ff8e579a-9a36-4ad7-a9f4-56450ee9b163
A patient is referred to the neurologist because of ataxia. Neurological examination reveals a loss of proprioception and a wide-based, slapping gate. Magnetic resonance imaging reveals degeneration of the dorsal columns and dorsal roots of the spinal cord. Which of the following organisms is most likely to have caused...
Haemophilus influenzae
Herpes simplex I
Neisseria gonorrhoeae
Treponema pallidum
3d
multi
The findings described are those of tabes dorsalis, a form of teiary syphilis caused by Treponema pallidum. Tabes dorsalis, and other forms of teiary syphilis, are now uncommon in this country, possibly because the common use of antibiotics may "treat" many unsuspected cases of syphilis. Haemophilus influenzae and Neis...
Microbiology
null
219a4732-bfe5-4ad0-aa2d-fcfe6119e513
Lymph flow is increased by all except
Increased vascular permeability
Decreased capillary osmotic pressure
Increase in interstitial fluid
Decreased interstitial osmotic pressure
3d
multi
Any factor that increases interstitial fluid pressure also increases lymph flow if the lymph vessels are functioning normally. Such factors include the following: * Elevated capillary hydrostatic pressure * Decreased plasma colloid osmotic pressure * Increased interstitial fluid colloid osmotic pressure * Increased per...
Physiology
Cardiovascular system
66fb9bee-4d05-4508-9644-f1704b5f4f03
Which of the following is not expected in a case of Microcytic Hypochromic Anemia:
Reduced serum Iron
Reduced Total RBC distribution Width
Normal Ferritin levels
Increased TIBC
1b
single
Answer is B (Reduced Total RBC distribution width Microcytic Hypochromic Anemias are typically associated with a Normal or High Red Cell Distribution Width Condition Test (normal values) Iron deficiency Thalassemia Sideroblastic anemia Anemia of chronic disease Smear Microcytic (MCV<80) Microcytic hypochromic Microcyti...
Medicine
null
24bb1f75-9ee7-4a84-8f82-5c995bc27aee
True about anaesthesia breathing circuit is
Cylinder is a pa of high pressure system
Oxygen flush delivers less than 35 litres
Oxygen flush delivers more than 135 litres
Pipelines is a pa of low pressure system
0a
multi
Cylinders -High pressure system Pipelines -Intermediate pressure system Oxygen Flush delivers 30 to 75lts and it is a pa of intermediate pressure system
Anaesthesia
Anaesthetic equipments
3ab4f0c8-c177-4380-8372-a1ff7e34896d
Edema is due to
Increased albumin in blood and decreased globin
Decreased albumin conc. in blood
Increased osmotic pressure
None of the above
1b
multi
null
Pathology
null
c17667e9-2ddd-428a-8b20-90d2478b3bc1
Widening of intercondylar notch of femur is seen in
Osteoarthritis
Rheumatoid arthritis
Hemophiliac Artheopathy
Charcot's joint
2c
single
null
Orthopaedics
null
b40df268-b747-4175-8927-ce80576c1625
Type-II error is
Rejecting true null hypothesis
Rejecting false null hypothesis
Accepting true null hypothesis
Accepting false null hypothesis
3d
multi
In statistical hypothesis testing a type I error is the rejection of a true null hypothesis (also known as a "false positive" finding or conclusion), while a type II error is the non-rejection of a false null hypothesis (also known as a "false negative" finding or conclusion). Much of statistical theory revolves around...
Social & Preventive Medicine
Biostatistics
bc3daeab-d3a7-4da7-b4d2-8549093e342e
A college student is surprised one morning by painful urination and a cream-colored exudate. Any person who acquires the gram-negative microbe that causes this infection is most likely to have acquired it via which of the following?
GI tract
Genitourinary tract
Nasal tract
Respiratory tract
1b
single
The respiratory tract is a common portal of entry to such airborne organisms as M. tuberculosis. This is why respiratory precautions must be taken when patients are harboring viable M. tuberculosis. The GI tract is usually infected from ingestion of contaminated food or water (Shigella, Salmonella, and Campylobacter) o...
Microbiology
Bacteria
4537a3b3-80d0-40ea-b854-f79adc170116
Most teratogenic in pregnancy
Phenytoin
Valproate
Barbiturate
Ethosuximide
1b
single
Valproate is the most teratogenic, phenytoin also isn't safe. Phenobarbitone, lamotrigine, topiramate are relatively safe drugs but 4mg folic acid is required per day. Ref: KD Tripathi 8th ed.
Pharmacology
Central Nervous system
b1c76634-d18f-4664-b008-c40c4e8badc2
. Peutz Jeghers polyps present most commonly in
Rectum
Colon
Esophagus
Jejunum
3d
single
Jejunum [Ref: Oxford textbook of medicine: Sections 18-33, Volume 3 By David A. Warrell 2005/e p6431 Oxford textbook of medicine writes- "The syndrome stigmata are obvious with multiple pigmented spots on the lips and buccal mucosa, and multiple benign hamaomatous polyps throughout the gastrointestinal tract, most freq...
Surgery
null
8f5e4dac-97a9-4e2b-bf88-dacb300241ef
True about anthropoid pelvis, sacrosciatic notch is :
Wide and shallow
Wide and deep
Narrow and shallow
Narrow and deep
0a
multi
Wide and shallow
Gynaecology & Obstetrics
null
3afb4faf-3ac8-4476-84f9-f782557b0d57
For foreign body causing sudden choking, most appropriate first line of management is?
Tracheostomy
Heimlich maneuver
Airway insertion
Laryngoscopy
1b
single
ANSWER: (B) Heimlich maneuverREF: Dhingras 4th ed p. 257Management of Laryngeal foreign body:A large bolus of food/ foreign body obstructed above the cords may make the patient totally aphonic, unable to cry for help. He may die of asphyxia unless immediate first aid measures are taken.H eimlichJs maneuvers: S udden th...
Anaesthesia
Fundamental Concepts
fa745ea0-a53b-4f4b-a46b-a619e6473f3a
The following statements are related to occipito posterior except
Malrotation of occiput may cause occipito sacral arrest
10% cases are associated with anthrapoid or android pelvis
Incomplete forward rotation of occiput may cause deep transverse arrest
Non rotation of occiput may cause are associated
1b
multi
In more than 50% the occipito posterior position is associated with either anthrapoid or android pelvis
Anatomy
Abnormal labor
6cf5dd50-4fc0-4feb-a46d-0d6b1d0e879e
Basal ganglia is involved in which types of memory
Conditioning
Procedural memory
Explicit memory
None
1b
multi
Procedural memory is required to do normal activities and it is from basal ganglia that the impulses for this arise. Therefore basal ganglia are involved in planning and programming of movements there fore is the site for procedural memory. Ganongs review of medical physiology; 23rd edition; pg:251.
Physiology
Nervous system