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135
54fa918b-28dd-4e10-8f60-d76dea9266cc
Example of asymmetric mixed-onium chlorofumarate is:
Rocuronium
Vecuronium
Gantacurium
Atracurium
2c
single
Gantacurium represents a new class of nondepolarizing neuromuscular blockers called asymmetric mixed-onium chlorofumarates. Ref: Miller's anesthesia-7th ed , Chapter 29.
Anaesthesia
null
c7c86bc0-c79c-4afc-b2e7-1e08bb0e507e
The optic cup is an evagination of which of the following?
Telencephalon
Diencephalon
Mesencephalon
Metencephalon
1b
single
The optic cup and its derivatives--the retina and optic nerve--develop from the diencephalon.
Anatomy
Eye, Nose and Ear
afd86569-9254-475f-be0f-d6c8db0a29f1
Best treatment for gas gangrene
Surgical debridement
Debridement with tetanus toxin
Debridement with iv penicillin
Debridement with polyvalent antitoxin
2c
single
"High-dose penicillin G and clindamycin, along with third-generation cephalosporins, should be given intravenously until the patient's toxicity abates. The mainstay of management is early surgical excision of the necrotic tissue " Bailey and love 26th edition Pg 430
Surgery
General surgery
8356d9a0-27b4-4931-9f3f-0953c5ca0887
Radium emits which of the following?
b, g
a, b, g
a, b
Neutrons
1b
single
Ans. is 'b' i.e., a, b, g o Radium emits a, b and g rays. Radium also produces neutrons when mixed with beryllium.
Radiology
Physics of Radiotherapy
10a0fac9-5df1-4254-86c2-d1df911e8be9
The attachment of the Actinomyces species to the tooth surface is facilitated by:
Fimbriae.
Cillia
Flagella.
Capsule.
0a
single
null
Pathology
null
5db0fb80-9ec6-499d-9dd9-c6a71c3eccfb
A 45 year old male presents with 4 X 4 cm, mobile right solitary thyroid nodule of 5 months duration. The patient is euthyroid. The following statements about his management are true except
Cold nodule on thyroid scan is diagnostic of malignancy
FNAC is required in fuher management of patient
The patient should undergo hemithyroidectomy if FNAC repo is inconclusive
Indirect laryngoscopy should be done in the preoperative period to assess mobility of vocal cords
0a
multi
Malignancy is present in 15% to 20% of cold nodules and in less than 5% of hot nodules. Although suggestive, malignancy of a nodule can be neither confirmed nor excluded based on radionuclide uptake. Note :Option "Patient should undergo hemithyroidectomy if FNAC repo is inconclusive " is controversial. Close surveillan...
Surgery
Endocrinology and breast
59b9cdbb-7839-4348-9985-2d19d0726e8b
Duration of action of flumazenil is:
5 minute
10 minute
20 minute
1-2 hours
3d
single
Flumazenil is absorbed orally ;oral bioavailability is ~16% but its not used orally .On I.v .injection ,action of flumazenil stas in seconds &last for 1-2 hours ;elimination t1/2 is 1 hour due to rapid metabolism. REF: KD Tripathi 8th ed.
Pharmacology
Central Nervous system
29a59fba-6225-4d49-a0cc-ffc1324506f8
Cryptococcal meningitis is common in:
Renal transplant recipient
A gamma globulinemia
Neutropenia
IgA deficiency
0a
single
Ans. is 'a' i.e., Renal transplant recipientPredisposing factors of cryptococcal meningitis are AIDS, hematologic malignancies, transplant recipients and patients on immunosuppressive or steroid therapy.
Microbiology
Mycology
ec889555-41a2-4c14-a232-092ab263610f
All of the following structures can be viewed through a bronchoscope, EXCEPT:
Trachea
Vocal cords
Subcarinal lymph nodes
First segmental division of bronchi
2c
multi
Subcarinal lymph nodes are mediastinal lymph nodes located around the carina on the other side of the tracheal wall and hence not visualized on bronchoscopy. Involvement of subcarinal nodes may be suspected on bronchoscopy by widening and fixity of the carina and/or paralysis of the vocal cords but these nodes cannot b...
ENT
null
44ea921b-acb4-4949-8ea1-b53bd50c402c
Hyperesthesia over the region of 12th is called
Murphy’s sign
Boa's sign
Moynihan's sign
Aaron's sign
1b
multi
Boa's sign is present in acute cholecystitis
Surgery
null
0ad73f37-daf5-4eb9-877e-ba9d75a05e5a
With regard to the malignant behavior of leiomyosarcoma, the most impoant criterion is
Blood vessel penetration by tumor cells
Tumor cells in lymphatic channels
Lymphocyte infiltration
The number of mitoses per high power field
3d
single
Option 4 is correct=the number of mitosis per high power field Leiomyosarcomas typically take the form of soft, hemorrhagic, necrotic masses. The diagnostic features of ove leiomyosarcoma include tumor necrosis, cytologic atypia, and mitotic activity. Robbins basic pathology 9th edition page no 694,heading=leiomyosarco...
Pathology
Breast
b3d0114f-293f-4a86-bd39-fc55069b4f7e
In which case Immunoguided surgery is done
CA colon
CA pancreas
CA jejunum
CA anal canal
0a
single
Ans is 'a' ie Ca Colon Radioimmunoguided surgery (RIGS) is a new technology capable of detecting minimal neoplastic lesions using radiocolloids, intraoperatively. It has numerous uses in oncology, it uses colloid radiotracers, monoclonal antibodies or non-immunological tracers. Its uses are Radioguided Occult Lesion Lo...
Surgery
Colon and Rectum - Polyps and Carcinoma
7a042f90-ab00-4c1d-a1fd-a5e2fdaaa64a
The maxillary sinus open intlo middle meatus at the level of:
Hiatus semilunaris
Bulla ethmoidalis
Infundibulum
None of the above
0a
multi
Ref: Dhingra 7e pg 151,209.
ENT
Nose and paranasal sinuses
b396b65b-e4bf-4db9-9270-4c5d317a4af2
Dutcher bodies are seen in?
Brain
Liver
Spleen
Bone marrow
3d
single
Ans. is 'd' i.e., Bone marrow * In multiple myeloma plasma cells can infiltrate the bone marrow diffusely or may be present in sheet like masses that completely replace normal elements.* Plasma cells may be normal plasma cells but mostly they are atypical plasma cells (variants of plasma cell) produced by intracellular...
Pathology
Blood
8ba14fb8-4711-4acd-8362-fe2ac5d583f7
Treatment of choice for placental site trophoblastic disease is -
Observation
Surgery
Chemotherapy
Radiotherapy
1b
single
Ans. is 'b' i.e., SurgeryPlacental Site Trophoblastic TumorArises from the placental bed trophoblasts and invades the myometrium.Most of these tumors run a benign course, malignancy is rare.Tumor is resistant to chemotherapy.Hysterectomy is the recommended treatment.
Gynaecology & Obstetrics
null
24eb90aa-ab2f-4b49-9d4d-5f9f0214c66e
Most common site of GIST is
Stomach
Small intestine
Large intestine
Spleen
0a
multi
Gastrointestinal Stromal Tumors Gastrointestinal stromal tumors (GISTs) are the most common sarcomatous tumors of the GI tract. Originally thought to be a type of smooth muscle sarcoma, they are now known to be a distinct tumor derived from the interstitial cells of Cajal, an intestinal pacemaker cell. They can appear ...
Anatomy
G.I.T
3dce91ab-2d5c-4ba2-a16f-85047dca6cf4
PSA is measured in which units
gm/ml
mg/ml
mcg/ml
ng/ml
3d
single
Ans. is 'd' i.e., ng/ml Prostate specific antigen* It is a glycoprotein produced only in the prostatic cells (both benign & malignant). It facilitates liquefaction of semen.* It is neither sensitive nor specific for early prostate carcinoma (it is prostate specific and not prostate cancer specific)y nevertheless it giv...
Surgery
Prostate & Seminal Vesicles
387a397a-b143-40af-9633-1b2f94991ac7
In Angle's classification for malocclusion, key tooth is:
MB cusp of Permanent Max. 1st molar
DB cusp of Permanent Max. 1st molar
MB cusp of Permanent Max. 2nd molar
MB cusp of Permanent Mand. 1st molar
0a
single
Angle’s postulate was that the upper first molars  were the key to occlusion and that the upper and lower molars  should  be  related  so  that  the  mesiobuccal  cusp  of  the  upper molar occludes in the buccal groove of the lower molar. If the teeth were arranged on a smoothly curving line of occlusion and this mola...
Dental
null
487bedd7-1bd7-4fda-a516-b9dbd60dda9a
Which is the most common type of persistent delusional disorder ?
Delusion of persecution
Somatic delusion
Delusion of jealousy
Delusion of grandeur
0a
single
Ans. A. Delusion of persecution Delusion of persecution is the most common type of persistent delusional disorder.
Psychiatry
null
d99c40cc-dedf-4767-a272-cbfc8f492fca
All age groups are included in numerator of dependency ratio except -
0-5 years
5-10 years
20-60 years
> 65 years
2c
multi
Numerator in dependency ratio includes:- i) 0-14 years (option a & b) ii) > 65 years (option d)
Social & Preventive Medicine
null
d043103e-7fb1-4308-bf51-749be1cdab13
True about Type 1 diabetes mellitus
Decreased hepatic Glucose output
Increase glucose uptake
Increased lipolysis
Decreased protein catabolism
2c
multi
* Patients may become hyperglycemic in poorly controlled type 1 diabetes mellitus . The reason being - due to lack of insulin to stimulate uptake and utilization of glucose and also because in the absence of insulin which antagonize the actions of glucagon, there is increase in gluconeogenesis from amino acids in liver...
Biochemistry
Metabolism of carbohydrate
301be874-e1b4-469c-89ee-f44aa1fee33b
Vitamin k associated clotting factors are
9,10
1,5
7,8
1,81
0a
single
Ref Robbins 8/e 118-119 ; 9/e p 119 Physiologic Effects of Vitamin K Vitamin K serves as an essential cofactor for a carboxylase that catalyzes carboxylation of glutamic acid residues on vitamin K-dependent proteins. The key vitamin K-dependent proteins include: Coagulationproteins: factors II (prothrombin), VII, IX an...
Anatomy
General anatomy
152bf82f-5a4d-4ddd-8bbe-e2af0e936b49
Anti-parkinsonism drug that is selective COMT inhibitor?
Entacapone
Ropinirole
Pergolide
Pramipexole
0a
single
Ans. a (Entacapone) (Ref. KDT 6th/pg. 415)ADRENERGIC DRUGSSr NoStep/siteActionDrugResponse1.Synthesis of NAInhibition Utilization of same synthetic pathwaya-methyl-p-tyrosine a-methyl dopaDepletion of NAReplacement of NA by a-methyl NA(false transmitter)2.Axonal uptakeBlockadeCocaine, desipra- mine, guanethidine, antih...
Pharmacology
C.N.S
8bde25f6-b875-4180-a04b-77092ba8f5c5
Loop of Henle handles the following ions except:
Na+
K+
CI?
Urea
3d
multi
D i.e. UreaIn the thick ascending limb, a carrier co-transpos one Na+, one K.' and 2C1-Q from the tubular lumen into the tubular cells.
Physiology
null
1dcde66d-58f8-4c4b-9b96-ea75ccb79beb
A 25 year old man undergoes orchiectomy for a testicular tumor. Microscopically, the tumor shows a variety of patterns, including lobules containing large cells with watery cytoplasm, structures resembling primitive glomeruli, syncytiotrophoblast, and shafts of undifferentiated cells with focal glandular differentiatio...
Choriocarcinoma
Embryonal carcinoma
Mixed tumor
Seminoma
2c
multi
This is a mixed testicular tumor. Mixed patterns occur in 60% of testicular tumors, with the most common pattern being teratoma (not present in this patient), embryonal carcinoma, yolk sack tumor, and hCG-containing syncytiotrophoblast. This patient's tumor also contains elements of seminoma. The prognosis of these tum...
Pathology
null
4bcd2c3f-2ce4-4ba4-bdc4-23614d87ba09
Following antimicrobials are termed as type I calcimimetics that mimic the stimulatory effect of calcium, on the calcium sensing receptor to inhibit PTH secretion by the parathyroid gland EXCEPT:
Streptomycin
Hamycin
Neomycin
Gentamicin
1b
multi
null
Pharmacology
null
9a580e1a-b525-4a65-9935-a0619feb7d29
Hormone synthesized as peptide precursor is/are
Insulin
PTO
Renin
Thyroid hormone
0a
single
Insulin- A polypeptide hormone secreted by the islets of Langerhans and functioning in the regulation of the metabolism of carbohydrates and fats, especially the conversion of glucose to glycogen, which lowers the blood glucose level.Ref: Ganong&;s review of medical physiology; 24th edition; page no: 431
Physiology
Endocrinology
64907cdc-3ef0-475b-b78b-2633c05c2711
The derivative of midgut among the following is
Rectum
Appendix
Liver
Stomach
1b
single
HUMAN EMBRYOLOGY-INDERBIR SINGH TENTH EDITION-PAGE NO:188Caecum and appendixThe caecal bud is a diveiculum that arises from the post aerial segment of the midgut Loop. The caecum and appendix are formed by the enlargement of this bud. The proximal pa of the bud grows rapidly to form the caecum. Its distal pa remains na...
Anatomy
General anatomy
6f15d9bf-48c6-4a16-af29-9c6e865e48b4
Kidney cortex contains:
Loop of henle
Pyramids
Collecting tubule and duct
Calyces
2c
single
Ans. C Collecting tubule and ductRef: BDC, 6th ed. vol. II pg. 315-16* The kidney consists of an outer renal cortex and an inner renal medulla that contains the renal pyramids which drain into - Calyx - Pelvis.* Cortex forms a continuous smooth outer zone with a number of projections (cortical columns) that extend down...
Anatomy
Abdomen & Pelvis
7c49853e-b89a-4f3c-8191-83ae435071fb
X-linked muscular dystrophy is?
Myotonic dystrophy
Spinal muscular atrophy
Neurogenic muscular atrophy
Duchene muscular dystrophy
3d
single
Ans. is 'd' i.e., Duchenne's muscular atrophy X-linked Recessive disordersMusculoskeletalHematologicalImmuneMetabolicNervous* Duchene muscular dystrophy* Chronic granulomatous disease* Hemophilia A & B* G-6-PD deficiency* Agamma - globulinemia* Wiskott - Aldrich synd.* Diabetes insipidus* Lesch Nyhan syndrome* Fragile ...
Pathology
Genetics
8f163e42-b08f-48ec-b031-79a59882983b
The diagnostic test for rickettsial infection is:
Weil-felix reaction
WIDAL
Sabin test
Culture
0a
single
Weil-felix reaction
Microbiology
null
024fa1a0-4c04-4a69-aea9-f26b971df0cb
Synchysis refers to
Collapse of the vitreous
Black spots in front of the eyes
Liquefaction of the vitreous
Detachment of the vitreous
2c
single
VITREOUS LIQUEFACTION (SYNCHYSIS) Vitreous liquefaction (synchysis) is the most common degenerative change in the vitreous. Causes of liquefaction: 1. Degenerations such as senile, myopic, and that associated with retinitis pigmentosa. 2. Post-inflammatory, paicularly following uveitis. 3. Trauma to the vitreous which ...
Ophthalmology
Vitreous and retina
aaabb6e9-661c-4073-a6cc-67c56dff62b4
Subclinical infection is seen in all except
Mumps
Poliomyelitis
Measles
Rubella
2c
multi
null
Social & Preventive Medicine
null
ddbda64a-d153-412b-b85e-3520f3458726
A 52 year old female presents with groin pain. Physical examination reveals a bulge in the groin area immediately inferior to the inguinal canal. The physician suspects that the patient has a femoral hernia containing a loop of small intestine. Which of the following structures is located immediately medial to the hern...
Femoral aery
Femoral nerve
Femoral vein
Lacunar ligament
3d
multi
A femoral hernia exits the abdominal cavity through the femoral ring to enter the femoral canal. The femoral ring is bounded medially by the lacunar ligament. Compression of the herniated intestine against the sharp edge of the lacunar ligament may cause strangulation of the intestine. The other borders of the femoral ...
Anatomy
null
89801c30-6f2a-4a30-8b12-cc14876c9791
Vitamin D from the skin or diet is metabolized primarily in the liver to 25-hydroxyvitamine D3. What is the rate limiting enzyme in Vitamin D synthesis?
25 cholecalciferol
1, 25-dihydroxycholecalciferol
24, 25- dihydroxycholecalciferol
7-dehydrocholesterol
1b
single
Vitamin D from the skin or diet is metabolized primarily in the liver to 25-hydroxyvitamine D3. 25D is the 'storage' form of vitamin D and is used to determine the vitamin D status of individuals. The last and rate limiting step in the synthesis of 'active' 1,25D is catalyzed by the mitochondrial enzyme 1 hydroxylase a...
Biochemistry
null
95aefc1d-3f4b-49b0-bb84-445d18d25138
Features of Von Willebrand disease are -
| BT and | PTT
| PT and | PTT
| PT
| CT
0a
single
Ans. is 'a' i.e., | BT and | PTT Von willebrand diseaseo Von willebrand disease is characterized by the deficiency of vWF, while the synthesis of factor VIIIc is normal,o vWF has two major function: -i) Helps in platelet adhesionii) Stabilizes factor VIIIc.o So, deficiency of vWF results in manifestation of both.Platel...
Medicine
Platelet Disorders
d237cc57-eef2-45f4-83b5-3b8b43bab93b
The design of choice for endodontic microsurgery is the:
Sulcular flap.
Sulcular partial-thickness flap.
Sulcular full-thickness flap.
Envelope flap.
2c
single
The design of choice for endodontic microsurgery is the sulcular full-thickness flap The mucogingival flap or Luebke-Ochsenbein flap is preffered for crowned anterior teeth for esthetic reasons. This flap which includes scalloped horizontal incision provides a guide for meticulous repositioning of the flap. The first k...
Dental
null
a2cba597-3313-4eb2-a461-1dfca7333cc7
All of the following can cause DIC during pregnancy except:
Diabetes mellitus
Amniotic fluid embolism
Intrauterine death
Abruptio placentae.
0a
multi
Ans. is a, i.e. Diabetes mellitusDIC is a pathological condition associated with inappropriate activation of coagulation and fibrinolytic system. It is a secondary phenomenon resulting from an underlying disease state.Obstetric conditions associated with DIC:More commonLess common* Intrauterine fetal death* Chorioamnio...
Gynaecology & Obstetrics
Antepartum Haemorrhage
8b64aecd-0d6a-41b0-91ae-0c008bb1d22b
The ideal treatment for fracture of the angle of mandible is
Transosseous wiring
Intermaxillary fixation
Plating on the Lateral side of the body of the mandible
Plating at the inferior border of the mandible
3d
single
null
Surgery
null
6acf39b0-a165-4b78-90fe-ec999c8d0ccd
The mother of a newborn boy is alarmed that her baby regurgitates at every feeding. An endoscopic examination reveals that the child's esophagus is almost completely occluded. This finding represents an example of which of the following errors of morphogenesis?
Aplasia
Atresia
Dysplasia
Dysraphic anomaly
1b
single
Atresia refers to defects caused by the incomplete formation of a lumen. Many hollow organs originate as strands and cords of cells whose centers are programmed to die, thus forming a central cavity or lumen. Atresia of the esophagus is characterized by partial occlusion of the lumen, which was not fully established in...
Pathology
Genetics
27a37d0c-501f-409a-a9c0-916de9b0e467
Investigation of choice for pericardial effusion is
MRI
CT
X ray
Echo
3d
single
Transthoracic echocardiography (TTE) is usually the initial investigation of suspected pericardial disease. It is cheap and widely available and has high accuracy for detecting pericardial effusions and signs of tamponade. TTE is also helpful for guiding diagnostic or therapeutic pericardiocentesis. Restricted acoustic...
Radiology
All India exam
bc0fee27-9e9f-49a1-a5b6-9a8716356455
True about hepatocelluar ca is -
Associated with HBV and HCV
Cirrhosis is predisposing factor
Fibrolamellar variety is not associated with cirrhosis
All
3d
multi
Answer is 'a' i.e. Associated with HBV & HCV; 'b' i.e. Cirrhosis is a predisposing factor; 'c' i.e. Fibrolamellar variety is not associated with cirrhoris "All patterns of hepatocellular carcinomas have a strong propensity for invasion of vascular channels." - Robbins
Surgery
null
a49d4ba7-61f5-45fc-8a8c-6a9921bd13df
A patient is having thick, gray coating on the throat and tonsils, followed with fever, chills and swollen glands in the neck. Microscopic examination of nasopharyngeal or pharyngeal swab showed gram positive organism with a special stain. The constitutes of the stain are:-
Crystal violet. Gram's iodine
Toluidine blue, malachite green, glacial acetic
Carbol fuchsin, acid alcohol, and methylene blue
Methylene blue
1b
single
Gram positive organism causing gray colored coating (pseudomembrane) is Corynebacterium diphtheriae . So the specific stain is Albe stain. Contents of Albe stain:-Stain A- glacial acetic acid, malachite green ,toluidine blueStain B- KI + I2
Microbiology
Systemic Bacteriology (Gram Positive Bacilli, Gram Negative Bacilli)
8cda4aeb-4ed5-45f7-b08b-34e29ebadfb1
Which of the following is known as abdominal policeman?
Omentum
Spleen
Liver
None of the above
0a
multi
In the early twentieth century, the British surgeon Rutherford Morison noted that the omentum tended to wall off areas of infection and limit the spread of intraperitoneal contamination. He termed the omentum the abdominal policeman. Ref: Schwaz's principle of surgery 9th edition, chapter 35.
Surgery
null
eaaac980-c33a-46d8-a316-02e213207922
Hernia with highest rate of strangulation is?
Direct inguinal hernia
Indirect inguinal hernia
Femoral hernia
Incisional hernia
2c
single
Femoral hernia REF: Sabiston 18th ed chapter 44 The likelihood of strangulation and need for hospitalization also increase with aging. Strangulation, the most common serious complication of a hernia, occurs in only 1% to 3% of groin hernias and is more common at the extremes of life. Most strangulated hernias are indir...
Surgery
null
65177662-775b-4ebe-9a44-4da3b44784ad
A 63-year-old man with hearing loss in his left ear complains of a loss of taste and drooling from the left side of his mouth. A CT scan shows a tumor compressing the nerve entering the skull through which of the following openings?
Foramen ovale
Foramen rotundum
Internal acoustic meatus
Jugular foramen
2c
single
The tumor is compressing the facial nerve, which runs through the internal acoustic meatus along with the vestibulocochlear nerve, which provides sense of taste to the anterior two thirds of the tongue via the chorda tympani and also mediates all of the facial muscles, except the muscles of mastication. The mandibular ...
Anatomy
Head & Neck
5b464f2e-5b66-4bcd-996a-d489bae097ae
Which of the following statements regarding ANB angle is false?
It measures the magnitude of skeletal jaw discrepancy
Vertical height of the face influences this angle
Position of the sella influences this angle
Position of the nasion influences this angle
2c
multi
The ANB angle indicates the magnitude of the skeletal jaw discrepancy. The magnitude of the ANB angle, however, is influenced by two factors other than the anteroposterior difference in jaw position. One is the vertical height of the face. As the vertical distance between nasion and points A and B increases, the ANB an...
Dental
null
3245f196-bcc0-4c7c-8abf-b702d4fdbce8
Cholinomimetic drugs can be used for the treatment of all the following conditions except.
Closed angle Glaucoma
Bradycardia
Cobra bite
Myasthenia gravis
1b
multi
Ans. (B) Bradycardia(Ref KDT 8th/e p114)Cholinomimetic drug will cause bradycardia as an adverse effect and thus cannot be used for its treatment.
Pharmacology
A.N.S.
37e100e7-52d2-4744-aa7a-daa3992d56e0
A 19 year old young girl with previous history of repeated pain over medial canthus and chronic use of nasal decongestants, presented with abrupt onset of fever with chills & rigor, diplopia on lateral gaze, moderate proptosis & chemosis. On examination optic disc is congested. Most likely diagnosis is:
Cavernous sinus thrombosis
Orbital cellulitis
Acute Ethmoidal sinusitis
Orbital apex syndrome
0a
single
Patient is suffering from cavernous venous thrombosis, as a complication of chronic ethmoidal sinusitis. The facial veins make clinically impoant connections with the cavernous sinus through the superior ophthalmic veins. Cavernous sinus thrombosis usually results from infections in the orbit, nasal sinuses, and superi...
Ophthalmology
null
69644927-c705-4384-868e-c400a82d4966
Following sign is seen in which condition:
Medial medullary syndrome
Lateral medullary syndrome
Benedict syndrome
Millar Gubler syndrome
0a
single
Ans. A. Medial medullary syndromeImage shows one sided deviation of tongue, i.e. paralysis of XIIth nervea. This occurs in Medial Medullary syndrome or Dejerine syndromeb. It occurs due to occlusion of anterior spinal arteryc. It is characterized by Ipsilateral XIIth nerve paralysis with contralateral hemiplegia.
Medicine
C.N.S.
4dd294a3-7283-48b3-9d33-09f043ebad8a
ESR in increased in -
Sickle cell anemia
Multiple myeloma
Polycythemia vera
Thalassemia
1b
single
Ans. is 'b' i.e., Multiple myelomaFactors affecting ESR 1. Plasmao RBCs carry a negative electric charge, whereas plasma carries a postive charge.o Any condition in plasma that increases its positive charge, increases rouleaux formation and increases ESR by lengthening stage I.o Following factors increase positive char...
Pathology
null
61202db0-3d61-45e2-948e-cdd0e006aade
Signature fracture of skull is seen in -
Gutter fracture
Depressed fracture
Ring fracture
Sutural separation
1b
single
Ans. is 'b' i.e., Depressed fracture
Surgery
Traumatic Brain Injury
a2b365ff-3410-452a-8658-902bf6df89ea
Light entering the eye passes through which retinal layer first?
Inner nuclear layer
Outer nuclear layer
Outer plexiform layer
Retinal ganglion layer
3d
single
The most anterior layer of the retina, through which light passes first, is the retinal ganglion layer. Light then passes through the other cell layers of the retina until it reaches the photoreceptors in the posterior region of the retina. Visual processing/Phototransduction occurs in the opposite direction(Photorecep...
Physiology
Special Senses
31e9183a-a1af-4cb0-aa7f-8c2cfa1d2584
Paltauf's hemorrhages are seen in: AP 11; NEET 13
Brain
Lungs
Hea
Liver
1b
single
Ans. Lungs
Forensic Medicine
null
d119ce91-883a-4ae9-ba51-44de27d95efd
Least common quadrant for breast carcinoma is
Upper outer
Upper inner
Lower outer
Lower inner
3d
single
Most common quadrant for breast carcinoma upper outer quadrant.
Surgery
null
e154bbf5-d4a9-4fb7-9a46-c7d7ac76c8ed
All of the following are features of mumps except _______
Caused by paramyxovirus
Aseptic meningitis is a complication
Orchitis is a complication in adults
Incubation period is less than 2 weeks
3d
multi
*Mumps is an acute viral infection characterised by painful enlargement of the salivary glands,most commonly the parotid glands.It is caused by an RNA virus of the genus paramyxovirus in the family paramyxoviridae. *It follows an incubation period of 2-4 weeks. Complications include epididymoorchitis in adolescent boys...
Pediatrics
Infectious disease
eea79fd1-5aec-4597-ab05-c456add7f31c
Which of the following does not changes in the old age:
GFR
Glucose tolerance
Haematocrit
Blood pressure
2c
single
C i.e. Hematocrit
Physiology
null
6ea031de-d4a8-4be6-984d-a0ca40be1080
A 16-year-old male complains of nasal obstruction, nasal blockage, a mass is seen in the nasopharynx with minimal extension into sphenoid sinus. What is the stage of nasopharyngeal fibroma?
IA
IB
IIA
IIB
1b
single
Ans. B. IB* Angiofibroma is the most common benign tumor of the nasopharynx.* It is typically seen in young adolescent males, i.e. occurs near puberty, hence called juvenile nasopharyngeal angiofibroma.Clinical features:* Recurrent episodes of profuse epistasis* Unilateral nasal obstruction* Nasal bones leading to broa...
ENT
Nose and PNS
8543f2ce-ec1f-44bc-baca-421f6b8c1730
Which antimalarial drug is known to cause neuropsy-chiatric adverse reaction?
Aesunate
Aimisnin
Quinine
Mefloquine
3d
single
Adverse effects :Mefloquine is bitter in taste; common reaction is dizziness, nausea, vomiting, diarrhoea, abdominal pain and sinus bradycardia. These are usually mild and largely dose related, but may be severe in some. Major concern has been a variety of neuropsychiatric reactions (disturbed sense of balance, ataxia,...
Pharmacology
Chemotherapy
7c7996cf-aa19-4f35-8b16-a67fd1bb3897
The most sensitive indicator of environmental iodine deficiency is
Serum T4 levels
Serum T3 levels
Urine iodine excretion
Neonatal hypothyroidism
3d
single
Ans. d. Neonatal hypothyroidism
Social & Preventive Medicine
null
08fd1340-756c-46ef-b8a8-10c66ede7188
Dementia is produced by deficiency of vitamin
Vitamin A
Vitamin D
Thiamine
Pyridoxine
2c
single
(C) Thiamine # DEMENTIA is the progressive decline in cognitive function due to damage or disease in the brain beyond what might be expected from normal aging.> Although dementia is far more common in the geriatric population, it may occur in any stage of adulthood.> This age cutoff is by definition, as similar sets of...
Psychiatry
Miscellaneous
fe50a882-04a1-45b4-a8fb-6fed0b2eb168
Local anaesthetic injected directly into the tissue -
Infiltration anaesthesia
Nerve block
Field block
Bier's block
0a
single
Ans. is 'a' i.e., Infiltration anaesthesia Infiltration anaesthesiao It is the injection of local anaesthetic directly into tissue without taking into consideration the course of cutaneous nerve.o It can be so superficial as to include only the skin, it also can include deeper structureso It is used for minor surgeries...
Anaesthesia
Miscellaneous (Local and Regional Anesthesia)
0d53908a-f831-46eb-97a0-f764c477e1a8
A 40 year old female patient complains of excessive bleeding. Patient gives a history of road traffic accident 5 hours ago and had a lacerated wound on lower back region. Blood grouping test reveals presence of antigen A and antigen B. This system for blood grouping consists of 3 major allelic genes which are located o...
Chromosome 8
Chromosome 9
Chromosome 10
Chromosome 7
1b
multi
→ This system consists of 3 major allelic genes; those are A, B and O. → They are located on long arm of chromosome 9. → These genes control the synthesis of blood group antigens A and B. → Based on the presence or absence of antigen A and antigen B, blood is divided into 4 groups i.e A, B, AB and O.
Pathology
null
7ac725b5-a59d-48cc-ac6a-242ec2ce1826
Fibrous pericardium in supplied by
Pericardiophrenic Nerve
Phrenic Nerve
T2 to T6 intercostal nerves
Vagus nerve
1b
single
Fibrous pericardium in supplied by phrenic Nerve. Visceral pericardium does not have somatic sensation.
Anatomy
null
fa39bc4c-eb92-4bd1-9331-02c0440326ce
A 70-years-old retired military person with good previous medical record complains of bi-temporal headache which is decreased in lying down position. He states that he gets relief by giving pressure over bilateral temples. The patient also complains of loss of appetite with feeling feverish. Diagnosis is:
Chronic tension headache
Temporal arteritis
Migraine
Fibromyalgia
0a
single
Ans. a. Chronic tension headache (Ref: Harrison 19/e p107t, p2587t, 2593-2594, 18/e p122, 2849)Tension-type Headache:Tension-type headache (TTH) is commonly used to describe a chronic head-pain syndrome characterized by bilateral tight, bandlike discomfortQ.Pain typically builds slowly, fluctuates in severity, and may ...
Medicine
Headache
7273f0e1-d1aa-472b-89de-7cfbc9e87a67
In basal body temperature method, after the rise of temperature, the unsafe period lasts for :-
24 hours
48 hours
72 hours
120 hours
2c
single
- In BBT, the rise of temperature signifies ovulation. - Since maximum survival of ovum post ovulation is 3 days, the unsafe period is 3 days post rise of body temperature. Other natural methods of contraception are: Calender method / feile period method/ safe period method/ rhythm method Cervical mucus method Symptoth...
Social & Preventive Medicine
Natural Methods, Barrier Methods, IUDs, OCPs
7634268e-6f3b-466b-a905-812682eb3ab2
Hypercalcemia is associated with all Except:
Hyperparathyroidism
Sarcoidosis
Milk alkali syndrome
Celiac disease
3d
multi
Answer is D (Celiac disease): Celiac disease is not a cause for hypercalcemia. Hyperparatlzyroidism, Sarcoidosis and Milk alkali syndrome, may all lead to hypercalcemia.
Medicine
null
6e9e2952-e746-4c28-bd65-e1e4dc89ecc8
Which is the best screening test to evaluate hearing in a neonate?
Pure Tone Audiometry
Stapedial Reflex
Otoacoustic Emissions
Brainstem evoked auditory response
2c
single
Otoacoustic emissions (OAEs) are objective, noninvasive, and rapid measures (typically less than 2 minutes) used to determine cochlear outer hair cell function. OAE testing is commonly used in newborn hearing screening because of its speed and noninvasive nature. It is also used in confirming pure-tone test results obt...
Pediatrics
null
33411849-200f-4a5c-85a6-3d69fd9a312a
A Toxic doses, zero order kinetics is seen in
Pencillin
Phenytoin
Valproate
Carbamazepine
1b
single
Phenytoin follows nonlinear (or zero-order) kinetics at therapeutic concentrations, because the rate of metabolism is close to the maximum capacity of the enzymes involved Ref-KDT 6/e p31
Anatomy
General anatomy
9d6dab05-675e-42b8-96ac-f5aba868555f
The use of combined oral contraceptive pill is associated with an increased incidence of:
Bacterial vaginosis
Chlamydial endocervicitis
Vaginal was
Genital herpes
1b
single
There is an overall reduction in the incidence of PID with OCPs but Chlamydial PID may increase. This is classically an indolent PID where the patient has no pain, no discharge.
Gynaecology & Obstetrics
Contraceptives
a689e89a-f0bf-4a9b-a5d9-b7fef65eef4a
Post-moem staining' is distinguished from bruise by all except
Occurs in dependent pas
Edges are clearly Defined
Absent in areas of body under pressure
Extravasation of blood into surrounding tissues occur
3d
multi
Extravasation of blood into surroundings tissues is not possible in postpaum staining. Ref synopsis of forensic medicine laxminarayana 4e
Forensic Medicine
Medico legal procedures
b65a3e7b-a4d6-4c8d-87e9-ba3b4f1e296b
All are true about Glomus body tumor except: (PGI May 2010)
Also k/a chemodectoma
Also k/a paraganglinoma
Common in older age
Brain Metastasis is common
3d
multi
Ans: D (Brain..) Chemodectomas (Glomus Body Tumors) Dewta 7th/720-22# These are uncommon group of neoplasms that may originate anywhere glomus bodies are found.# The lesions are rare before the age of 20, there is a female predominance in some series, and the lesions may occur in multiple sites in about 10% to 20% of c...
Medicine
Oncology
f30117b4-a6c6-4a9d-8a13-b06ecb6d8249
Blood supply of premolars comes from:
Same source as that of molars
Same source as that of anteriors
Posterior superior alveolar artery
Both 1 and 3
3d
multi
null
Dental
null
6e3ec920-eff1-4912-9e61-3181e3e947b4
The most common site of implantation in ectopic pregnancy is -
Ampulla
Fimbriae
Body
Infundibulum
0a
single
Ans-A Ampulla .The most common site of ectopic pregnancy is a fallopian tube (as if and in fallopian tube the most common site is Ampulla (55%).Sites of ectopic pregnancy in fallopian tube in decreasing order of frequency :AmpullaIsthmusInfundibulumInterstitial
Unknown
null
c4d050b6-9c49-4370-9e33-cf93a6c99b95
An epidemiologic study observes increased numbers of respiratory tract infections among children living in a community in which most families are at the poverty level. The infectious agents include Streptococcus pneumoniae, Haemophilus influenzae, and Klebsiella pneumoniae. Most of the children have had pneumonitis and...
Vitamin A
Vitamin B1
Vitamin E
Vitamin D
0a
single
Vitamin A is important in maintaining epithelial surfaces. Deficiency of this vitamin can lead to squamous metaplasia of respiratory epithelium, predisposing to infection. Increased keratin buildup leads to follicular plugging and papular dermatosis. Desquamated keratinaceous debris in the urinary tract forms the nidus...
Pathology
Environment & Nutritional Pathology
3b71f9a9-a205-4ba2-8554-2d5d98acbca5
Bullous impetigo is caused by ?
Streptococcus
Staphylococcus
Staphylococcus
Y. Pestis
1b
single
Ans. is 'b' i.e., Staphylococcus Impetigo Impetigo is a highly contagious, Gram-positive bacterial infection of superficial layer of epidermis. Impetigo occurs in Two forms : ? 1. Non - bullous impetigo (Impetigo contagiosa) It is the most common bacterial infection of children (occurs mainly in children in contrast to...
Skin
null
828951b0-52c8-44c0-ad77-cf896d26e156
Hand over mouth exercise (HOME) is an effective behavioral modification technique in the age group of:
3 to 6 years
Under 3 years
6 to 9 years
Above 9 years
0a
multi
null
Dental
null
a45bdfaf-f9fe-40ed-a380-076009d548fb
Which of the following are the objective tests of refraction ?
Retinoscopy
Refractometry
Keratometry
All the above
3d
multi
Ans. is 'd' i.e., All the above
Ophthalmology
null
b0a1ac53-3bf5-43a3-ab0f-7b77a0ff9fa6
In substantia nigra, the major neurotransmitter is:
Dopaminergic
Acetylcholine
Noradrenaline
GABA
0a
single
Ans. A. Dopaminergica. There is a system of dopaminergic neurons in nigrostriatal dopaminergic system with cell bodies in substantia nigra and axon endings in caudate nucleus.b. In Parkinson's disease there is loss of dopaminergic cells in the substantia nigrawhich leads to striatal dopamine depletion.c. As DOPAMINE ac...
Physiology
Nervous System
1bac9c7a-4d6b-4dc2-9a52-b9db24579498
Rh negative mother, ICT negative was given Anti D at 28 week of pregnancy. Which of the following is the follow up schedule?
Give another dose of Anti D within 72 hour postpaum depending on the baby blood group and DCT
Give another dose of Anti D 72 hour postpaum irrespective of baby blood group
Anti-d immuno globulin has no effect on the status of the Indirect coombs test
Next dose of anti D at 34 weeks
0a
single
Anti D in Rh negative women: Anti-D immune globulin is given prophylactically to all D negative, unsensitized women at approximately 28 weeks' gestation, and a second dose is given after delivery if the newborn is D-positive. There are various recommendations regarding a second dose after 6 weeks of the first injection...
Gynaecology & Obstetrics
RH Incompatibility
a655c4fb-d4ea-4a6a-b77c-5f7ab5cc4b75
Which of the following pigments accumulates in liver in Dubin-Johnson syndrome?
Monoglucuronate bilirubin
Epinephrine metabolite
Bilirubin pigment
Melanotic pigment
1b
single
Ans. b (Epinephrine metabolite) (Ref. Robbins Pathologic basis of disease 7th/ 887-888; Table 18-4)Dubin-Johnson syndrome# Hereditary defect in hepatocellular excretion of bilirubin glucuronides across the canalicular membrane due to absence of the canalicular protein, the multidrug resistance protein 2 (MRP2; located ...
Pathology
Liver & Biliary Tract
6cd5b8b6-92de-4d4f-948a-edc28912e378
Floor of 4th ventricle has ?
Infundibulum
Vagal triangle
Mammillary body
Tuber cincrium
1b
single
Floor of 4th ventricle (Rhomboid fossa) It is diamond or rhomboidal shaped and is formed by posterior surface of pons (upper triangular pa or pontine pa) and dorsal surface of medulla (lower triangular pa or medullary pa) junction of pons and medulla forms intermediate pa. Features of 4th ventricle are :? Median sulcus...
Anatomy
null
eb690583-32cc-4d8b-b97b-52f14a23d31c
Visual acuity is a measure of:
Light sense
Form sense
Contrast sense
All of the above
1b
multi
Ans. Form sense
Ophthalmology
null
38c0a29a-7cec-48f6-b80e-63400c23e194
Precancerous lesion of gall bladder is
Porcelain gall bladder
Mirrizi syndrome
Cholesterosis
Acalculous Cholecystitis
0a
multi
Ans is 'a' ie Porcelain gall bladder "The calcified porcelain' gallbladder is associated with more than a 20% incidence of gallbladder carcinoma. These gallbladders should be removed, even if the patients are asymptomatic" - Schwartz SurgeryMirizzi SyndromeBiliary obstruction may occur in cases of acute cholecystitis, ...
Surgery
Gallbladder Cancer
fbe5853c-1451-4c8b-a6ab-f5b573f17e50
A 35 yr old male female singer presents with complains of hoarseness, vocal fatigue & pain in neck on prolonged phonation. Direct laryngoscopy shows bilateral pin head size swelling on Ant.1/3 & post 2/3 junction of vocal cord. What could be the probable diagnosis ?
Vocal polyp
Vocal nodule
Acute laryngitis
Acute pharyngitis
1b
single
Vocal nodule (singer's or screamer's node) Seen symmetrically on the free edge of vocal cord, at the junction of anterior one third, with the posterior two thirds (i.e. area of maximum vibration of cord). Vocal nodules are bilateral. Mostly seen in teachers, vendors, actors or pop singers as they speak in unnatural low...
ENT
ENT Q Bank
ae18677d-998c-4d9c-8a58-901d395d32fc
Lowest risk of malformations is seen with which of the following antiepileptic drug?
Phenobarbitone
Valproate
Lamotrigine
Carbamazepine
2c
single
A metanalysis of 31 studies found lamotrigine and levetiracetam to carry the lowest risk of malformations(Ref: William's Obstetrics; 25th edition)
Gynaecology & Obstetrics
All India exam
6a3f485a-48ca-4cee-bf08-ae07feddf874
Column concept of spine stability was given by -
Denis
Frenkel
Wilson
Todd
0a
single
REF : textbook of ohopedics, John ebnezer, 4th edition ,pg.no.311 Three column concept of spine stability was given by Denis *The anterior column consists of anterior half of the veebral body , anterior pa of the disk & anterior longitudinal ligament. * The middle column consists of posterior half of the body & the dis...
Orthopaedics
Spinal injuries
a320b0ed-abfe-4a6a-b5be-e1400f0a1d7d
Kernig's sign is seen in: September 2009
Viral encephalitis
Pyogenic meningitis
Brain abscess
All of the above
1b
multi
Ans. B: Pyogenic Meningitis The main clinical signs that indicate meningism are nuchal rigidity, Kernig's sign and Brudzinski's signs. None of the signs are paicularly sensitive; in adults with meningitis, nuchal rigidity was present in 30% and Kernig's or Brudzinski's sign only in 5%. Nuchal rigidity is the inability ...
Medicine
null
6e0ac85f-9a0c-433c-8b18-9625d484a699
In osteogenesis imperfecta the defect is in the:
Synthesis of type I collagen
Mineralisation of osteoid
Osteoclast function
Osteoblast formation
0a
single
Ans; a (Synthesis of type I collagen) Ref: Robbins, ed, p. 1279Osteogenesis imperfecta is due to deficiency in the synthesis of Type I collagen structures affected are - bone, joints,eyes, ear, skin and teethCytogenetic abnormality:Mutation in the genes that codes for a1, and a2 chains of collagen autosomal dominant in...
Pathology
Osteology
61bb9e94-7ea8-4de4-ad6e-ee95a08717d9
A 28-year-old lady has put on weight (10 kg over a period of 3 years) and has oLigomenorrhoea followed by amenorrhoea for 8 months. The blood pressure is 160/100 mm of Hg. Which of the following are the most appropriate investigations -
Serum electrolytes
Plasma cortisol
Plasma testosterone and ultrasound evaluation of pelvis
T3, T4 and TSH
1b
single
null
Medicine
null
254378b3-a343-46d2-a847-58efe34cb24d
Which of the following muscles is responsible for abduction of vocal cord
Posterior cricoarytenoid
Lateral cricoarytenoid
Cricoarytenoid
Transverse arytenoid
0a
single
null
ENT
null
30fee938-7827-45b8-9db7-4d7b71d0cd20
A 30 year old male patient was on Isoniazid therapy for Tuberculosis.He developed rashes on exposed pas of body.He has disoriented memory. Family members gives history of diarrhea also.What is the diagnosis?
Isoniazid neuropathy
Tuberculosis skin lesions
Niacin deficiency
Some other drugs has caused this
2c
single
Isoniazid inhibits the endogenous syntheisis of Niacin so,the patient developed dermatitis,diarrhea,dementia. Prolonged treatment with Isoniazid leads to Pyridoxine deficiency,which is required for endogenous synthesis of niacin Reference: Harpers illustrated biochemistry 30th edition
Biochemistry
Metabolism of protein and amino acid
5c451cce-f4fe-474a-b7d5-1f5df653b855
Rokitansky Kuster Hauser syndrome is associated with:
Ovarian agenesis
Absent fallopian tube
Vaginal atresia
Bicornuate uterus
1b
multi
Ans. is b, i.e. Absent fallopian tubeTo understand why distal part of fallopian tube is present:Mullerian ducts grow downward, therefore there will be cases where there will be well formed abdominal ostia associated with hypoplasia or absence of the remainder of the tubes, uterus and vagina or the tubes and uterus may ...
Gynaecology & Obstetrics
Malformation of the Female Generative Organs
3caa1963-12c3-4399-87a7-7f6dc029b1a5
What is the most common cause of failure of radiotherapy for stage II cervical carcinoma?
Liver metastasis
Bone metastasis
Para-aortic node metastasis
Resistance of the central tumor
2c
single
In stage II cervical cancer, the incidence of nodal involvement is 25%-40%. Most tumors are not radioresistant, and distant metastasis (i.e., a more advanced stage) are a late complication of more advanced stages of the disease.
Surgery
Urethra & Penis
7effcd3e-b1a2-43cb-9168-d9ef4cce9915
A young male presented with dyspnea, bleeding and petechial hemorrhage in the chest after 2 days following fracture shaft of the femur right side. Most likely cause is:
Air embolism
Fat embolism
Pulmonary thromboembolism
Amniotic fluid embolism
1b
single
Ans. (b) Fat embolism* Fat embolism usually manifests following Long bone fractures* MC after Closed fractures > Open fractures* MC in Young (more bone marrow) > Old* MC in Long bones (Femur) > Pelvis> Smaller bones* 90% will develop fat emboli after traumatic fracture but only 1-5% develop fat embolism syndrome* Also ...
Surgery
Acute Arterial Occlusion
b7c44394-91fc-46f4-bd6e-f7e1433c7511
Which is not an endogenous catecholamine ?
Dopamine
Dobutamine
Adrenaline
Noradrenaline
1b
single
null
Pharmacology
null
3aa631c4-ef46-4ca4-8598-d3337f221de8
The patient is being administered i.v. quinine following which he developed restlessness and sweating, the most likely cause is :
Hypoglycemia
Cinchonism
Arrhythmias
Sweating
0a
single
null
Pharmacology
null
2730f920-08de-4a6e-8a59-e045aa4cfb95
A female with H/o oligohydramnios during her pregnancy, brings her newborn baby to OPD, on noticing asymmetric thigh folds in her child. The examiner performs flexion, IR and abduction, which produces a click sound. Which is the test done by the examiner?
Oolani test
Von Rosen test
Mc Murray's test
Barlow's test
0a
single
Clinical Diagnosis - DDH based on the following 1. Abduction is limited (especially in flexion) 2. Asymmetric thigh folds Oolani's Test--the first two alphabets O and R (Oolani for Reduction) and for Reduction we do abduction of hip. It is similar to 2nd pa of Barlow's test McMurray circumduction test is used to evalua...
Orthopaedics
Pediatric Ohopedics
d0cdb418-5640-4797-99dc-4f662352b236
Most desirable structure to anastomose with esophagus is:
Stomach
Jejunum
Colon
Duodenum
0a
single
Ans. (a) StomachRef Schackelford Page 256 7th edition* Best conduit for esophageal replacement-- Stomach* Best conduit for short segment replacement of esophagus-- Jejunum* Best conduit in cases of corrosive injury to stomach and esophagus-- Colon
Surgery
Oesophagus
78133f9a-c5f7-4f6b-8037-70231bf030d2
WHO recommended dose of misoprostol in the treatment of post partum hemorrhage is
400 mcg oral
600 mcg sublingual
800 mcg sublingual
1000 mcg oral
2c
single
Ans. (C) 800 mcg sublingual(Ref: WHO recommendations for prevention and treatment of PPH 2012)According to WHO 2012 recommendationsOxytocin is drug of choice for treatment and well as prevention of post partum hemorrhage.Alternatives are ergometrine, fixed dose combination of oxytocin and ergometrine and misoprostolMis...
Pharmacology
Endocrinology