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135
8e1e6e00-795c-4ae9-895e-46b5b5901d63
Dangerous area of the eye is
Retina
Sclera
Ciliary body
Optic nerve
2c
single
Any trauma to the ciliary body can cause sympathetic ophthalmitis ; hence it is considered the dengerous area of the eye
Ophthalmology
Trauma
5215c0e9-a187-43d0-9e44-fa0df712fcc5
Renshaw cells are inhibitory interneurons found in:
Gray matter of brain
White matter of brain
Gray matter of the spinal cord
White matter of spinal cord
2c
single
Renshaw cells are inhibitory interneurons found in the gray matter of the spinal cord. They receive axonal collaterals from nearby motor neurons; it inhibits the activity of the same or related adjacent motor neurons. This recurrent inhibition by the Renshaw cell facilitates and sharpens the activity of the projecting ...
Physiology
null
c0bba3c9-6080-4f01-bfe0-ed2c12dac76a
Coronary ligaments of the knee joint connect ?
Menisci to tibia
Menisci to femur
Lateral meniscus to capsule
Anterior horns of both menisci
0a
multi
CORONARY LIGAMENT * Fibrous Capsule is attached to periphery of Menisci. * Connects the periphery of the menisci to the tibia * They are the poion of the capsule that is stressed in rotary movements of the knee ref : maheswari 9th ed
Orthopaedics
Forearm wrist and hand injuries
d0fd8328-8d07-447e-9e8b-d7ef0cc190e5
A 55-year-old obese woman complains of declining visual acuity. Funduscopic examination shows peripheral retinal microaneurysms. Urinalysis reveals 3+ proteinuria and 3+ glucosuria. Serum albumin is 3 g/dL, and serum cholesterol is 350 mg/dL. These clinicopathologic findings are best explained by which of the following...
Peripheral insulin resistance
Increased peripheral insulin uptake
Irregular insulin secretion
none of the above
0a
multi
- Given clinical features point towards nephropathy & retinopathy resulted as complication of type-2 DM - Type-2 diabetes mellitus results from complex interplay b/w Underlying insulin resistance in its metabolic target tissues (liver, skeletal muscle & adipose tissue) & Reduction in glucose-stimulated insulin secretio...
Pathology
Diabetes
b4d3ffb7-e255-42f9-a6e8-42e0e16b4625
Thalidomide is useful in: March 2007
Treatment of leprosy
Treatment of type II lepra reaction
Treatment of type I lepra reaction
Treatment of neuritic leprosy
1b
single
Ans. B: Treatment of type II lepra reaction Thalidomide is a sedative-hypnotic, and multiple myeloma medication. The drug is a potent teratogen. Thalidomide was chiefly sold during the late 1950s and early 1960s to pregnant women, as an antiemetic to combat morning sickness. Children were born with severe malformities,...
Pharmacology
null
95d73339-35aa-4e4c-aa0f-d794980d0487
Transitional cell carcinoma bladder caused by
Schistosomiasis
Ascariasis
Malaria
None
0a
multi
Risk factors for transitional cell carcinoma (TCC) of the bladder - 1. Smoking → Major etiological factor. 2. Occupational exposure to chemicals → Nephthylamine benzidine, aniline dyes, acrolein. 3. Schistosoma haematobium (Bilharziasis) → It is a risk factor for both TCC & SCC. 4. Drugs → Phenacetin 5. Cyclophosphami...
Pathology
null
a64fb4eb-33a7-4c4b-8cf2-0b33b24855da
Krogmans table system is used for ?
Age determination
Sex determination
Dental examination
Calculating estimated height
1b
single
Ans. is 'b' i.e., Sex determination Krogman's table is used to determine the percentage of accuracy in sex determination from isolated skeletal pas.According to Krogman, the degree of accuracy in sexing adult skeletal remains is :-Entire skeleton - 100 %Pelvis alone 95 %
Forensic Medicine
null
e1820e13-9867-47cc-b460-38512a9aee76
When gold fused with porcelain is fired at very high temperature, greenish discoloration of cervical margin is due to:
High firing temperature
Disintegration of opaque layer
Presence of silver
Formation of excess oxides
2c
single
Discoloration of the porcelain near the cervical region of the metal-ceramic prosthesis has been reported to occur when a silver-containing alloy is used as the substrate. Color changes included green, yellow-green, yellow-orange, orange and brown hues. This discoloration  phenomenon has generally been called “greening...
Dental
null
72e1ea09-ebfa-4edc-b229-84793671050f
Which glaucoma is associated with cataract
Phacomorphic glaucoma
Neovascular glaucoma
Phacoanaphylactic glaucoma
Buphthalmos
0a
single
Answer- A. Phacomorphic glaucomaPhocomorphic glaucoma :- It occurs in intumescent stage of cataract. The swollen lens leads to relative pupillary block (pupillary block glaucoma), iris bombe and angle closure. It is a type of angle closure glaucoma and anterior chamber is very shallow.
Ophthalmology
null
c984f959-1138-41b5-b9a3-2343cf79f377
Sideroblastic anemia is caused by all except ?
Collegen vascular disease
Iron deficit
Lead poisoning
Cutaneous porphyria
1b
multi
Ans. is 'b' i.e., Iron deficit Causes of sideroblastic anemia Hereditary o X-linked recessive sideroblastic anemia. Acquired Hematological Drugs & chemicals Others Myelofibrosis INH RA Myelodysplasia Penicillamine Myxedema Acute leukemia Lead SLE Lymphoma Alcohol Iron overload Myeloma Pyridoxin dificiency Porphyria Pol...
Pathology
null
5ba96faa-ab71-4f2c-bf37-cb3bc6dd890a
Treatment of diabetic retinopathy neovascularisation is/are -
Retinal laser photocoagulation
Pars plana vitrectomy
Phacoemulsion
LASIK
0a
single
Retinal laser photocoagulation is the ideal treatment for treating diabetic Retinopathy neovascularization. Ref AK khurana 6/e p 282
Ophthalmology
Vitreous and retina
d44971d3-d692-41ba-96f5-ece5966fc710
Noninfective cause of genital ulcer is -
Behcets disease
Hansen's disease
Ramsons's disease
Syphilis
0a
single
Bechet's disease is characterized by a triad of recurrent oral ulcers (aphthous ulcers), recurrent genital ulcers and uveitis. Important non-infective causes of genital ulcer are Trauma, Bechet's disease, Stevens-Johnson syndrome and carcinoma.
Dental
null
50ce5733-98c6-4404-8dc5-a8488a0bb819
45-year-old female has history of slip in bathroom complaints of pain right hip, tenderness in scarpas triangle and normal X-ray. Next investigation is:
USG guided aspiration
CT
MRI
Bone scan
2c
single
(c)This case refers to post-traumatic pain in proximal femur, scarpas triangle refers to area of femoral neck and for stress or occult fracture of neck femur where traumatic marrow edema is seen - MRI is investigation of choice.
Orthopaedics
Miscellaneous
3f9d4916-e88e-4898-b34f-736f3dbe7e57
A 9 years old child presented to OPD with complaints of high grade fever, vomiting, one episode of seizure. CSF examination was done and Gram staining of the culture showed the following finding. What is the probable causative agent
Haemophilus influenzae
Streptococcus pneumoniae
Neisseria meningitidis
Escherichia coli
1b
single
* Gram staining clearly shows Gram positive cocci (violet/purple coloured) in pairs - classical image of Streptococcus pneumoniae or pneumococci. Infections caused by Pneumococcus: - * Pneumonia * Meningitis * Otitis media * Bacteremia * Septic ahritis * It is the most impoant cause of infections in splenectomy patient...
Microbiology
Bacteriology
e5afdbc9-c31c-46be-a1c9-6f396bbfd50c
CVEK pulpotomy is not known by the name:
Partial pulpotomy.
Cervical pulpotomy.
Pulp curettage.
None
3d
multi
null
Dental
null
d8e7b8fb-6bbe-410e-9ce5-0865456f5f6b
Most common site of glioblastoma multiforme is-
CP angle
Frontal lobe
Brainstem
Occipital lobe
1b
single
Ans. 'b' i.e., Frontal lobe A glioblastoma multiforme (GBM) is a type of brain tumour called an astrocytoma. Astrocytomas are some of the most common brain tumours. They develop from the highly vascular and quickly reproducing astrocyte cells in our brain and are often malignant.
Pathology
CNS Tumors
cbf6f5fa-0ea7-4541-8ae2-9ef6edbbc3ca
Pataus syndrome due to -
Trisomy 21
Trisomy 18
18 P
Trisomy 13
3d
single
Ans. is 'd' i.e., Trisomy 13 Trisomv 13 (Patau's syndrome)Head & FaceChestExtremitieso Scalp defects (cutis aplasia )o Congenital heart diseaseo Overlapping of finger &o Microphthalmia, comeal(VSD, PDA, ASD in 80%)toes (Clinodactyly, polydactyly)abnormalitieso Thin posterior ribs (missingo Hypoplastic & hyperconvexo Cl...
Pathology
Mendelian Disorders: Single-Gene Defects
04c8b466-4b33-47c4-b1ea-669ae84d1f1b
"Opioids" differ from "opiates" in that they are:
More powerful in action
More long acting
Synthetic derivatives
Derived directly from opium
2c
single
Opiods are synthetics while opiates are semi synthetic. Opiods include pethidine,fentanyl,methadone,dextropropoxyphene,tramadol. Semisynthetic opiates include heroin ,pholcodine,ethylmorphine . Ref: KD Tripathi 8th ed.
Pharmacology
Central Nervous system
34984002-d5ba-43ac-810d-7067cc12fce0
Beta HCG is secreted by
Ovary
Pituitary
Corpus luteum
Placenta
3d
single
In molecular biology, human chorionic gonadotropin (hCG) is a hormone produced by the syncytiotrophoblast, a component of the feilized egg, after conception. Following implantation, the syncytiotrophoblast gives rise to the placenta.Ref: Ganong&;s review of medical physiology; 24th edition; page no:-414
Physiology
Endocrinology
9294dd10-66b0-499a-8c5c-b1aa175dc434
An eight year old boy presents with back pain and mild fever. His plain X-ray of the dorsolumbar spine reveals a solitary collapsed dorsal vertebra with preserved disc spaces. There was no associated soft tissue shadow. The most likely diagnosis is -
Ewing's sarcoma
Tuberculosis
Histiocytosis
Metastasis
2c
single
Solitary collapsed vertebra (vertebra plana) with preserved disc spaces in a child suggests the diagnosis of Eosinophilic granuloma (a type of Histiocytosis).
Radiology
null
b42ade47-c019-49f0-bc47-12f174b12cc9
Persistent marrow aplasia is caused by which hepatitis virus: September 2006
HAV
HBV
HCV
None of the above
3d
multi
Ans. D: None of the abovePersistent marrow aplasia appear after a variety of viral infections, most commonly viral hepatitis of the non-A, non-B, non-C, non-G type, which is associated with 5% to 10% of cases.
Pathology
null
fc6ccef4-7f57-4688-a1c8-6ec6d991c176
True regarding secular trends-
Changes in disease pattern in terms of months
Changes in disease pattern seasonally
Changes in disease pattern over a sho period of timer
Changes in disease pattern over a long period of time
3d
multi
.long term or secular trends implies changes in the occurrence of disease over a long period of time.generally several years or decades.a secular trend implies a consistent tendency to change in a paicular direction or a definitive movement in one direction. ref:park&;s textbook,ed 22,pg no 63
Social & Preventive Medicine
Epidemiology
c7a05329-8bbd-4a18-92ad-e1bd5d7493f0
Alagille syndrome is
Bile duct paucity
IHBR dilation
PBC
PSC
0a
single
Alagille syndrome is an autosomal dominant genetic disorder affecting liver,hea,kidney,etc.Liver biopsy in Alagille syndrome shows too few bile ducts(bile duct paucity) or in some cases,the complete absence of bile ducts(biliary atresia).Bile duct paucity results in reduced absorption of fat & vitamins(A,D,E,K) which m...
Surgery
G.I.T
fc3110ba-dbf1-4a4b-beaa-9abad5cb3a03
Griesofulvin is not useful in one of the following
Tinea capitis
Tinea Cruris
Tinea versicolor
Tinea pedis
2c
single
Refer CMDT 2010/110 *griesofulvin is used for dermatophytoses including Tinea capitis, Tinea cruris, Tinea pedis, Tinea ungunum and Tinea corporis *Tinea versicolor is caused by yeast Malassezia furfur .it is treated by selenium sulfide AMD ketaconazole shampoo
Anatomy
General anatomy
e98e19f6-b6bc-4ffe-a651-abd151a2438c
Human is dead end host for?
Malaria
Typhoid
Bubonic plague
Filaria
2c
single
Ans. is 'c' i.e., Bubonic plague A dead end host is an infected person from which infectious agents are not transmitted to other susceptible host or from which a parasite cannot escape to continue its life cycle. The diseases in which human acts as dead end host, i.e., dead and disease : ? Japanies encephalitis Trichin...
Microbiology
null
18c74b15-2428-44b9-9780-ddb73c772d1e
Mucin secreting Goblet cells are present in all of the following structures, EXCEPT:
Small intestine
Large intestine
Esophagus
Stomach
3d
multi
The classic example of a unicellular, exocrine gland is the goblet cell, found scattered among epithelial cells lining the trachea, small intestine, and colon. The cell has a narrow base and an expanded apex filled with secretory granules. These cells secrete mucin. Goblet cells are not found in the normal stomach, so ...
Anatomy
null
0b206a1d-b712-4b19-9e5c-c54b8565e671
Which of the following is the causative agent of a variety of cutaneous warts (plantar, common, and flat) and is associated with cervical neoplasia?
Human papillomavirus
West Nile virus
Tick-borne encephalitis virus
Polyomavirus
0a
single
Human papillomaviruses (HPV) are the causative agents of cutaneous warts as well as proliferative squamous lesions of mucosal surfaces. Although most infections by human papillomavirus are benign, some undergo malignant transformation into in situ and invasive squamous cell carcinoma. Both HPV and polyomavirus have ico...
Microbiology
Virology
7455b458-75ee-46de-8d81-296d073f9ffc
Most commonly injured tarsal bone-
Talus
Navicular
Cunieform
Calcaneum
3d
single
*Calcaneum is the most commonly fractured tarsal bone. ref : maheswari 9th ed
Orthopaedics
Thigh, Knee,Leg,Foot & Ankle injuries
a0af329b-4fee-4d27-8e6f-ed89064ac2e5
Who is the Father of Public Health?
Cholera
John snow
Edward Jenner
Louis Pasteur
0a
single
Father of Modern medicine - Hippocrates Father of Indian medicine - Charaka Father of Modern surgery - Ambroise pare Father of Indian surgery - Sushruta Father of Epidemiology/ Modern Epidemiology - John Snow Father of Bacteriology - Louis Pasteur Father of Genetics - Mendel Father of Public Health - Cholera Father of ...
Social & Preventive Medicine
Disease Causation, Measurements, Milestones
4cf38f7e-d6d9-4729-a2d8-37c63a5b6576
Which of the following HLA types is associated with IDDM?
HLA DR3, DR4
HLA B27
HLA B47
HLA DR2
0a
single
Major susceptibility gene for Type 1 DM is located in the HLA region on chromosome 6. 95% of patients with IDDM express HLA DR3 or DR4. Concordance rate of Type 1 DM in identical twins ranges between 40- 60%. Type 2 DM has a strong genetic component. The concordance of type 2 DM in identical twins is between 70 and 90%...
Medicine
null
1ddc270d-5c02-4077-8fb1-b284e9e94df3
Nernst potential of Na+ is
94
61
-64
-94
1b
single
Equilibrium potential of ions is calculated by NERNST EQUATION. For Na, it is +60 mV to +55mV approximately (REF: GANONG'S REVIEW OF MEDICAL PHYSIOLOGY -23rd EDITION. Page No-7)
Physiology
General physiology
fb4ab748-707e-467e-b484-b1795052fa78
Nelson syndrome is associated with:
BRCA2 mutation
Prophylactic craniospinal irradiation
Subarachnoid hemorrhage
Bilateral adrenalectomy
3d
single
Nelson syndrome refers to development of ACTH secreting pituitary macroadenoma after therapeutic bilateral adrenalectomy.
Surgery
null
8ddffe15-d231-4180-af63-fc24363b7ba4
Which of the following group of enzymes act by mediating transfer of one molecule to another?
Lyases
Oxidases
Peptidases
Transferases
3d
single
Transferases catalyze the transfer of groups such as methyl or glycosyl groups from a donor molecule to an acceptor molecule e.g., hexokinase. Ref: Harper's Illustrated Biochemistry, 26th Edition, Pages 49-50; Textbook of Biochemistry By D M Vasudevan, 3rd Edition, Page 31
Biochemistry
null
1d0d3b27-aafa-4d73-83ab-5e93a999a7bb
The three germ cell layers in embryo separate by the process of?
Ovulation
Neurilation
Gastrulation
All of the above
2c
multi
Ans. C. Gastrulation.(Ref: Langman's Medical Embryology 9th/pg. 65).Longman's Medical Embryology 9th/pg. 65.........."The most characteristic event occurring during the third week of gestation is gastrulation, the process that establishes all three germ layers (ectoderm, mesoderm, and endoderm) in the embryo. Gastrulat...
Anatomy
Fertilization and Development of Embryo
48a5ef44-59e7-4d30-a9c5-3f15da5236d6
Id, ego, superego are terms coined by ?
Sigmand Freud
Bleuler
Moral
Kraepelin
0a
single
Ans. is 'a' i.e., Sigmoid freud IMPOANT CONTRIBUTORS IN PSYCHIATRY Term Demence precoce Coined by Dementia precox Catatonia, cyclotymia Hebephrenia Schizophrenia Ambivalence Free association Psychoanalysis, Psychodynamics Id, ego, Superego Psychiatry Moral Emil Kraepelin Kahlbaum Hecker Eugen Bleuler Eugen Bleuler Sigm...
Psychiatry
null
7dfb2ea5-57b2-4a94-9ef6-be3853d0c16e
According to Kim's classification of microsurgical cases, which class represents a tooth with an apical lesion and complete denudation of the buccal plate but no mobility:
Class C
Class D
Class E
Class F
3d
single
Kim's classification of microsurgical cases   Class A: Represents a tooth with no periradicular lesion, no mobility, and normal pocket depth. The clinical symptoms have not resolved, though non-surgical options have been exhausted. Clinical symptoms are the only reason for the surgery. Class B: Represents a tooth with p...
Dental
null
285cb867-45cf-4422-b3df-6e4ddbca335b
Bitemporal hemianopic field defect is charactersitic of -
Glaucoma
Optic neuritis
Pituitary tumour
Retinal detachment
2c
single
Sagittal (central) lesions of the chiasma. These are characterised by bitemporal hemianopia and bitemporal hemianopic paralysis of pupillary reflexes. These usually lead to paial descending optic atrophy. Common causes of central chiasmal lesion are: suprasellar aneurysms, tumours of pituitary gland, craniopharyngioma,...
Ophthalmology
Neuro-ophthalmology
7d361a80-269c-4cfd-a56f-fa3f924642aa
'Dropped shoulder' occurs due to paralysis of -
Deltoid
Teres major
Trapezius
Serratus anterior
2c
single
Dropped shoulder occurs due to paralysis of Trapezius.
Anatomy
null
d8a1a0b3-84f0-4e15-8a7b-bc2a8a43c540
Cullen's sign is seen in
Acute cholecystitis
Acute pancreatitis
Acute hemorrhagic pancreatitis
Blunt injury abdomen
2c
single
Signs indicative of retroperitoneal bleeding in severe pancreatitis Flank ecchymosis - Grey Turner sign Periumbilical ecchymosis- Cullen's sign Inguinal ecchymosis - Fox sign Ref: Sabiston 20th edition Pgno : 1527
Anatomy
G.I.T
f88da465-cb31-4d43-9dcf-da19b9481d2a
A young lady lost her job, loss of appetite wakes up at 3 am. What's the diagnosis
Depression
Schizophrenia
OCD
Mania
0a
single
In this question, the details are inadequate, however among the given options the best answer is A, depression
Psychiatry
Mood disorders
9d6d23c3-6105-4166-b071-4258be776ea9
Second primary malignancy of head and neck is commonly associated with which of the following
Oral cavity
Hypopharynx
Larynx
Paranasal sinuses
0a
single
Ans. a. Oral cavity Second primary malignancy of head and neck is commonly associated with oral cavity. "The site of index cancer influences the most likely site of a second primary malignancy, as an example, in a series of 1257 patients with SCC of the head and neck, patients with an index malignancy arising in the la...
Surgery
null
06812b3f-9599-4370-bb1a-a8a3f33285d2
Treatment of choice in a perimenopausal woman with bleeding PV due to multiple fibroids Is :
TAH with BSO
TAH
Vaginal hystrectomy
Enucleation of fibroids
1b
single
TAH
Gynaecology & Obstetrics
null
2a21046d-f34b-4a5e-9c12-ed0cc8f09dcb
Transmigration of WBC across the endothelium is called
Margination
Rolling
Pavementing
Diapedesis
3d
multi
Ans. (d) Diapedesis(Ref: Robbins 9th/pg 76-77)Migration of the leukocytes through the endothelium, is called transmigration or diapedesis.It is mediated by PECAM-1
Pathology
Inflammation & Repair
6deb17ee-9cf3-4031-b770-e815d5ea74af
All can be used for systemic fungal infections except :
Ketoconazole
Fluconazole
Amphotericin B
Griseofulvin
3d
multi
null
Pharmacology
null
dc196982-0cee-4434-a4a0-ea8a446ef857
In Down's syndrome -
Gap (sandle gap)
Cliodactyly
Hypotonia
All
3d
multi
null
Medicine
null
84f3ce25-166e-4049-9b64-a08cb210cabb
The EEG cabins should be completely shielded by a continuous sheet of wire mesh of copper to avoid the picking of noise from external electromagnetic distrubances. Such a shielding is called as -
Maxwell cage
Edison's cage
Faraday cage
Ohm's cage
2c
multi
null
Radiology
null
c3d36333-77f0-4606-a63b-6170b34c5cdd
A 12 year old boy has a productive cough characterized by large volumes of foul-smelling sputum. Three years ago, the patient was diagnosed with pancreatic insufficiency, as evidenced by repetitive gastrointestinal symptoms of steatorrhea. After culture of the sputum, colorless, oxidase-positive colonies with a fruity ...
A CFTR protein lacking a phenylalanine in exon 10 at position 508
A GTP-binding protein involved in the elongation step of protein synthesis
A GTP-binding protein similar to the one coupled with & alpha 2-adrenergic receptors
A GTP-binding protein similar to the one coupled with & beta-adrenergic receptors
1b
multi
The boy is displaying the characteristic symptoms of cystic fibrosis with bronchiectasis (accounting for the foul-smelling sputum) and pancreatic insufficiency, producing steatorrhea. However, the question directly relates to the infectious agent causing the pneumonia, Pseudomonas aeruginosa, an oxidase-positive bacter...
Microbiology
null
e0d06a70-0195-480b-9e62-7fcbb545edb7
Patient with a history of fall presents weeks later with headache and progressive neurological deterioration. The diagnosis is:-
Acute subdural hemorrhage
Extradural hemorrhage
Chronic subdural hemorrhage
Fracture skull
2c
multi
Chronic Subdural Hematoma Chronic SDH: collection of blood breakdown products that is at least 3 weeks old Chronic SDHs often occur in patients without a clear history of head trauma, as they may arise from minor trauma . A chronic SDH >1 cm or any symptomatic SDH should be surgical drained .
Surgery
Cerebrovascular Diseases
1d254d63-92aa-4c07-841b-6efc97fe944c
Vaginal bleeding in a neonate is commonly due to:
Sarcoma boytroides
Trauma of delivery
Hormonal withdrawal
Viral infection
2c
single
Hormonal withdrawal
Gynaecology & Obstetrics
null
879e3509-d92c-4b1b-a368-03835d6403ed
True statement about standard normal curve:
Equal distribution on either side of the curve
The total area under the curve is 2
Its mean is 1
Standard deviation is 0
0a
multi
(Refer: K. Park’s Textbook of Preventive and Social medicine, 24th edition, pg no:886 ) Normal distribution Gaussian / Standard distribution Symmetric with respect to same mean, median & mode & frequencies tapers off rapidly and symmetrically on both sides
Unknown
null
9091d246-5f0a-43c8-b7a0-d7cd70bd0b27
You have given ViPS vaccine to a person. How often will you ask him to take booster doses?
Every year
Every 2 year
Every 3 year
Every 4 year
2c
single
The injectable typhoid vaccine ViPS is a single dose vaccine which requires booster doses every 3 year. Ty21a vaccine is the oral typhoid vaccine. 3 doses are taken on day 1,3 and 5. It is effective for up to 7 years after last dose. It is recommended in people travelling to endemic areas and during out breaks. Ref: Pa...
Social & Preventive Medicine
null
cc55e214-01ab-4381-8b9a-060f7d2f965c
A pt. was treated with amitryptiline for depression developed urinary retention, constipation and blurring of vision, most likely cause is :
Anticholinergic side effects
Expressed symptoms of depression
Superadded prostatic enlargement
Any of the above
0a
multi
Ans. is 'a' Anticholinergic side effects Tricyclic Antidepressants have prominent Anticholinergic side effects. Symptoms are -Dry mouthBad TasteBlurred vision (mydriasis)ConstipationUrinary retentionEpigastric distress
Psychiatry
Pharmacotherapy Management of Children and Adolescents
bd7b8fe6-7af1-4322-939c-66b5fe0e317d
Paraplegia involves;
Both the upper limb.
Both the lower limb .
One upper and lower limb.
Any of the above.
1b
multi
Paraplegia is due to impairment in motor or sensory function of the lower extremities.
Medicine
null
0d543615-357d-497b-bac7-344e0668dbce
In shigella dysentry associated Hemolytic Uremic syndrome, the false statement is
Leucocytosis
Neurological abnormalities
Hepatic Failure
Thrombatic Angiopathy
2c
multi
Hemolytic uremic syndrome (HUS) is a well-described process that is known to cause severe renal dysfunction, thrombocytopenia, and anemia. HUS is typically associated with toxins (shiga-like and shigella toxin) found in strains of E. coli and Shigella spp . Haemolytic uraemic syndrome (HUS), which is comprised of the t...
Pediatrics
Urinary tract
ff78e421-87be-4809-9626-f8ab3005f923
Which of the following is not used in enterococcal infection?
Vancomycin
Linezolid
Teichoplanin
Cephalexin
3d
single
Ans: d (Cephalexin) Ref: Harrison, 16th ed, p. 830; Tripathi, 6th ed, p. 733Enterococci are resistant to all cephalosporins; therefore this class of antibiotics should not be used for treatment of enterococcal infections. Usual treatment for enterococci is combination of penicillin or ampicillin with an aminoglycoside....
Pharmacology
Anti Microbial
21221870-22db-4e25-b5da-7262819e5ab5
Which of these are seen on Romanowsky stain -a) Reticulocytesb) Basophilic stipplingc) Heinz bodiesd) Howell-Jolly bodiese) Cabot ring
abcd
bcde
acde
abde
3d
single
Romanowsky dyes are used for staining blood films. They are made up of combination of acid and basic dyes. The nucleus and neutrophilic granules are basophilic and stains blue. Hemoglobin is acidophilic and stains red. Various modifications available are Leishman’s stain, Wright’s stain, Giemsa and Jenner’s stain. Baso...
Pathology
null
7efa8bf2-84be-4f58-b2a7-df846c2ab5ec
Which of the following is not an adverse effect of chronic amiodarone therapy ?
Pulmonary Fibrosis
Hypothyroidism
Hyperthyroidism
Systemic lupus erythematosis
3d
single
null
Pharmacology
null
778467a1-7c40-4afb-9b77-ce954d48be0a
Drug used for hypertension and pulmonary edema due to scorpion sting:
Prazosin
Clonidine
Furosemide
Mannitol
0a
single
Ans. (A) Prazosin(Ref: Harrison 20th/e p3329)Scorpion sting is a dreadful medical emergency.Scorpion stings cause a wide range of symptoms, from severe local reactions to cardiovascular, respiratory and neurological manifestations.Alpha-receptors play vital role in the pathogenesis of cardiac failure and pulmonary edem...
Pharmacology
A.N.S.
729a1a8d-b505-4b1b-b783-9e2de1c0ab37
A boy has developed epistaxis. What is the treatment of choice
Digital pressure
Nasal packing
Cauterization of vessels
Surgical ligation
0a
single
Most of the time, bleeding occurs from the Little's area and can be controlled by pinching the nose with thumb and index finger for about 5 min. This will compress the vessels of the Little's area Ref: Dhingra 7e pg 199.
ENT
Nose and paranasal sinuses
8fd3038f-e287-411d-a18c-d2ad3b194252
Which of the following is NOT true about amniotic fluid index (AFI)?
It is calculated by adding the veical depths of the largest pocket in each of four equal uterine quadrants
Fluid restriction may lower the AFI
Significant hydramnios is defined by an index greater than 24 cm
There is steady increase in AFI after 36 weeks
3d
multi
Amniotic fluid index (AFI) is calculated by adding the veical depths of the largest pocket in each of four equal uterine quadrants. Significant hydramnios is defined by an index greater than 24 cm. Fluid restriction or dehydration may lower the AFI. Peak AFI is seen at approximately 32 weeks followed by a steady declin...
Gynaecology & Obstetrics
null
e854c247-5e20-48f1-9b01-fd32fcb4049c
Commonest site of oesophagus - squamous cell carcinoma is
Upper 2/3
Middle 1/3
Lower 1/3
Crico-esophageal junction
1b
single
OESOPHAGEAL CARCINOMA,6 th most common carcinoma in the world, can be predisposed to dietary deficiencies, human papillomavirus infections, achalasia cardia, oesophageal webs etc.it is most commonly seen in middle third of oesophagus (50%)and also at lower third(33%) and upper third(17%).in the lower pa adenocarcinoma ...
Surgery
G.I.T
d9e3f657-f8c4-4fff-8197-840adcec860f
According to myogenic hypothesis of renal autoregulation, the afferent aerioles contract in response to stretch induced by
NO release
Noradrenaline release
Opening of ca2+ channels
Adenosine release
2c
single
Most vascular beds have an intrinsic capacity to compensate for moderate changes in perfusion pressure by changes in vascular resistance, so that blood flow remains relatively constant. This capacity is well developed in the kidneys (), but it has also been observed in the mesentery, skeletal muscle, brain, liver, and ...
Physiology
Renal physiology
b8d8db6d-c47f-40d8-b43d-1ad959f039ec
An ophthalmoplegic migraine means
When headache is followed by complete paralysis of the III rd and VI nerve on the same side as the hemicrania.
When the headache is followed by paial paralysis of the IIIrd nerve on the same side as the hemicrania with out any scotoma.
Headache associated with IIIrd, IVth and VIth nerve paralysis.
Headache associated with optic neuritis
0a
single
Ophthalmoplegic migraine is characterized by recurrent attacks of ophthalmoplegia, following severe migrainous headaches. The condition almost always begins in childhood, and is considered to be rare in adults. However, OM may occur for the first time in adult life. The typical clinical picture of OM includes a child w...
Medicine
All India exam
68a7037f-154c-4d12-a4fa-85de8d305283
The monsaccharide glucose is best described by which one of the following statements?
It usually exists in the furanose form
It is a ketose
It possesses an anomeric C-2 carbon atom
It forms part of the disaccharide sucrose
3d
multi
Two monosaccharide units are linked by a glycosidic bond or yield 2 monosaccharide units on hydrolysis. Depending on their reducing property, they are divided into: Nonreducing disaccharides: The functional groups are involved in the glycosidic bond formation, hence free functional groups are not available Reducing di...
Biochemistry
null
232d8b77-14ad-4ae1-9424-fa8196bdc7b5
During ocular surgery, when eye surgeon touches the medial rectus, he asked to assistant to measure heart rate because of
Occulocardiac reflex
Occulocephalic reflex
Occulovagal reflex
None
0a
multi
null
Anaesthesia
null
fd8e92e3-7f9f-420a-a61d-a07a1bb48c5f
A female at 37 wks of gestation has mild labour pain for 10 hours and cervix is persistently 1CM dilated but non effaced. What will be the next appropriate management?
Sedation and wait
Augmentation with syntocin
Cesarean section
Amniotomy
0a
single
This is a nulliparous patient and is in latent phase of labor. Latent phase duration normally in a nulliparous female is less than 20hrs and in a multiparous female its is 14 hours. The optimal treatment for this patient is administer sedation and observe the patient. Prolonged latent phase occur when the duration exce...
Gynaecology & Obstetrics
null
a7c00419-565b-4941-84d5-4a53e7950318
Contraceptive LNG-IUD (levonorgesterol intra-uterine device) has the cumulative pregnancy rate at 5 yrs of:
0.5
1
1.5
2
0a
single
This is the closest choice in reference to the claimed rate by the manufacturer after phase three trials where the five-year cumulative pregnancy rate is 0.7 percent.LNG-IUD releases approximately 20 mcg levonorgestrel per day initially then 10 mcg /day. LNG does not increase the risk of PID. Lesser ectopic pregnancy a...
Gynaecology & Obstetrics
Contraceptives
0f68bf8a-a999-4f1e-9a14-db1bb9721792
A 40 year old man has megaloblastic anemia and early signs of neurological abnormality. The drug most probably required is:
Folic acid
Iron sulphate
Erythropoietin
Vitamin B12
3d
single
Deficiency of vitamin B12 results in megaloblastic anemia and demyelination. It can cause subacute combined degeneration of spinal cord and peripheral neuritis.
Pharmacology
Hematology
bc2ef716-e969-4384-8265-b99d61755164
Study the following carefully -(AI 05)Read the pedigree. Inheritance pattern of the disease in the family is -
Autosomal recessive type
Autosomal dominant type
X-Linked dominant type
X-linked recessive type
3d
single
X-linked recessive type
Unknown
null
c942875d-a60a-4fef-b113-c1adb1891219
False about Gastric lymphoma is:
Stomach is the most common site
Asosciate with H. pylori infection
Total gastrectomy with adjuvant chemotherapy is the treatment of choice
5 yr survival rate after treatment is 60%.
2c
multi
Total gastrectomy with adjuvant chemotherapy is the treatment of choice [Ref: Sabiston 20th Ed. ; Schwaz 11th Ed. Stomach is the most common extranodal site of lymphoma. It is of two types - Primary & Secondary Primary gastric lymphoma - is lymphoma of the stomach which exhibits no evidence of liver, spleen, mediastina...
Surgery
All India exam
cbce2581-e1b8-458e-8b9b-0f53deaf0644
Wimberger ring sign is present in:
Rickets
Scurvy
Secondary syphilis
Tuberculosis
1b
single
Wimberger ring sign - seen in scurvy
Pediatrics
Scurvy
2ea62a14-d58f-4f20-b6db-7d10e5c2a062
Renal tuberculosis is characterised by -
Loin pain
Painful hematuria
Sterile pyuria
Constitutional symptoms
2c
single
null
Surgery
null
4b40bc88-ed51-4594-a0ec-949679ec57b6
Mycophenolate mofetil is used in
Prevention of organ transplantation rejection
Tuberculosis
Leprosy
Methanol posisoning
0a
single
Mycophenolate mofetil is an immunosuppressant used to prevent rejection of allogeneic cardiac, hepatic, and renal transplants. It is administered orally or intravenously. indications It is used to prevent rejection of organ transplants and for prophylaxis of organ rejection in allogeneic cardiac transplants. Contraindi...
Physiology
General physiology
14e67c31-0045-414c-ad36-8a97d2c7966b
Liver cirrhosis is associated with which type of emphysema in Pizz phenotype mutation?
Centriacinar
Panacinar
Paraseptal
Multifocal
1b
single
In individuals with the Pizz phenotype, alpha 1 antitrypsin deficiency, its blood levels are less than 15% of normal, and patients are likely to develop panacinar emphysema at a young age; 50% of these patients will develop liver cirrhosis, because the A1AT is not secreted properly and instead accumulates in the liver....
Medicine
null
933bcb42-e319-404a-979e-27446ae1afb6
An addict presents with increased sweating, lacrimation, diarrhea, yawning and rhinorrhea. These symptoms may occur due to withdrawal of?
Heroin
Cocaine
Cannabis
Alcohol
0a
single
Heroin is a semi synthetic derivative of opium. Withdrawal symptoms are lacrimation, sweating, yawning,anxiety,restlessness, rhinorrhoea and tremors seen 8-12 hours after last dose. All the other drugs donot have the above set of side effects. Ref: KD Tripathi 8th ed.
Pharmacology
Central Nervous system
93d4dad2-b320-428c-b321-989c22fd3d5a
Chemotherapy for dysgerminoma is:
Cisplatin, etoposide, bleomycin
Cyclophophamide, vincristine, prednisolone
Adriamycin, cyclophophamide, cisplatin
Methotrexate, oncovin, cyclophosphamide
0a
single
Management of Dysgerminoma: • The treatment of early dysgerminoma. Surgical – including resection of the primary lesion (unilateral oophorectomy) and proper surgical dissection. • Metastatic Disease – Chemotherapy or Radiation therapy. Chemotherapy: The most frequently used chemotherapy regimens for germ cell tumors ar...
Gynaecology & Obstetrics
null
be1a6b30-129c-4c1a-b072-d10775050b1b
Which of the following is a Longer acting Erythropoietin derivative?
Sargramostim
Darbepoetin alfa
Dornase alfa
Oprelvekin
1b
single
Darbopoietin is a Long acting EPO derivative drug. It has a T1/2 24-36 hrs. So it is given once a week. Epoietin has a half life of 6-10 hrs. Uses - Anemia of chronic renal failure(CRF) Anaemia in AIDS patients treated with Zidovudine. Cancer chemotherapy induced anaemia. Preoperative increased blood production for Aut...
Pharmacology
Hematology
b2fe0d72-a8c4-4054-9cba-68489dcdf1a4
Methods of fusing two cells in genetic recombination technique include all of the following techniques, except
Fusion mediated by Ethylene Glycol
Fusion mediated by by Electric current
Fusion mediated by viral transformation
Fusion Mediated by altering membrane viscocity
3d
multi
Ref: <a href="
Biochemistry
Metabolism of nucleic acids
8682f1eb-6d58-4948-9e7c-d279770a0f08
Best way to plot the changes of incidence of disease over time is:
Histogram
Line chart
Scatter diagram.
Ogive.
1b
single
null
Dental
null
b44bf8bb-266b-4441-8183-5ace93c2215d
Sensitivity is -
True positive/true positive + false negative
True positive/false positive + true negative
True negative/true negative + false positive
True negative/false negative + true positive
0a
multi
Ans. is 'a' i.e., True positive/true positive + false negative Sensitivity =Number of true positive--------------------------------------------Number of true positives + Number of false negative
Social & Preventive Medicine
Screening for Disease
c2ae4328-5284-454d-9c5f-7b9583b0e6ab
Topical Mitomycin C is used for _________
Endoscopic treatment of angiofibroma
Treatment of skull base osteomyelitis
Sturge Weber syndrome
Treatment for laryngeal stenosis
3d
single
Topical application of Mitomycin C after endoscopic dilatation of laryngotracheal stenosis prevents restenosis. Mitomycin-C (MMC) inhibits fibroblast proliferation and synthesis of extracellular matrix proteins, and thereby modulates wound healing and scarring. Mitomycin C is an antibiotic isolated from Streptomyces ca...
ENT
null
79bf64f7-5219-44f8-a68b-5a5987ed37db
Refsum's syndrome is associated with -
Retinitis pigmentosa
Xerophthalmia
Chalcosis
Diabetes retinopathy
0a
single
Ans. is 'a1 i.e., Retinitis pigmentosa Associations of retinitis pigmentosa1. Ocular associations : These include myopia, primary open angle glaucoma, microphthalmos, conical cornea and posterior subcapsular cataract.2. Systemic associations : These are in the form of following syndromesLaurence-Moon-Biedl syndrome : I...
Ophthalmology
Dystrophies and Degenerations
2cc1b386-7da7-49eb-852d-a0dc1fa3c153
Most common presentation of chronic pancreatitis
Nausea
Steatorrhea
Pain
Brittle Type 3 diabetes
2c
single
Ans. (c) PainRef: Bailey and Love 27th ed; pg. 1230* MC symptom of Chronic pancreatitis - Pain* Site of pain depends on the foci of disease:# Head: Epigastric and Right Subcostal Pain# Left Side pancreas: Back pain# Diffuse pain is also seen sometimes.# Radiation to shoulder also can be seen
Surgery
Pancreas
e399a7ab-5984-42c7-8ef6-8b429d7ae680
The chief cause of perinatal moality in term frank breech presentation is :
Intracranial hemorrhage
Prolapse of umbilical cord
Delay in delivery of head
Abnormalities
0a
single
Intracranial hemorrhage
Gynaecology & Obstetrics
null
0eb57c66-a806-4ed1-ab8c-4b38be214a2b
Treatment of a cause of Endometriosis at a younger age group :
Progestin
Danazol
GnRH analogues
Hysterectomy with oophorectorny
0a
single
Ans. is a i.e. Progestin Adolescent Endometriosis : The incidental finding of minimal to mild endometriosis in a young woman without immediate interest in pregnancy is a common clinical problem. 70% of girls with chronic pelvic pain unresponsive to OCP's or NSAID's are affected by endometriosis. Mild disease can be tre...
Gynaecology & Obstetrics
null
f0de0471-12a8-4abc-85be-3637e4c1f06b
When can one diagnose acute respiratory distress in a child?
Within 7 days of known insult
Respiratory failure not fully explained by cardiac failure
No left ventricular dysfunction
All of the above
3d
multi
Diagnostic criteria of ARDS in children: BERLIN DEFINITION CRITERIA Timing Within 1 wk of a known clinical insult or new or worsening respiratory symptoms Chest X-rays or tomography scan Bilateral opacities not fully explained by effusions, lobar/lung collapse, or nodules Origin of edema Respiratory failure not fully e...
Pediatrics
Other Respiratory Disorders
08fe2a9e-7d0a-471c-bb4a-3d03e296d2cc
Not true regarding influenza virus is -
All types exhibit antigenic shift
Onlybtype A shows antigenic drift
Drift is accumulation of point mutations
None of the above
0a
multi
Antigenic drift the gradual sequential change in antigenic structure occurring regularly at frequent intervals. Antigenic drift is due to mutation and selection. It accounts for the periodic epidemics of influenza. REF:ANANTHANARAYAN AND PANIKER'S TEXTBOOK OF MICROBIOLOGY 9TH EDITION PAGE NO-499
Microbiology
Virology
517cd3b0-d40b-4b0a-8ea5-43c9292c6434
Anterior cerebral artery supplies which part of brain?
Anterior
Lateral
Medial
Posterior
2c
single
Most of the medial surface is supplied by the anterior cerebral artery. It also supplies the medial part of the orbital surface of the frontal lobe Middle cerebral artery supplies most of the superolateral surface of brain. It also supplies the temporal lobe and the lateral part of the orbital surface of the frontal lo...
Anatomy
null
33588beb-3f1f-4364-8901-c766018154bb
Secretomotor fibers in the superior salivatory nucleus pass through the following nerves to reach the Submandibular ganglion:
Facial nerve.
Chorda tympani.
Lingual nerve.
All of the above.
3d
multi
null
Anatomy
null
55c5ae59-837c-41e4-a0c1-6194206c6073
Call Exner Bodies are seen in :
Dyserminomas
Hilus cell tumours
Brenner's
Granulosa cell tumours
3d
multi
Granulosa cell tumours
Gynaecology & Obstetrics
null
78778ac3-5e24-4ab0-be90-3828d96a7941
Diabetes is associated with all of the following in the elderly EXCEPT
Cerebrovascular accident
Cognitive decline
Fall risk
Myocardial infarction
2c
multi
null
Medicine
null
24d55131-5f56-4367-8e09-90b5b1d0f2ab
Glomerular basement membrane showing "tram-track" appearance is seen in
Membranoproliferative Glomerulonephritis type 1
Membranous nephropathy
Focal Segmental Glomerulosclerosis
Minimal-Change Disease
0a
single
Membranoproliferative Glomerulonephritis (MPGN) type 1:MPGN is best considered a pattern of immune-mediated injury rather than a specific disease. The glomeruli are large and hypercellular. The glomeruli have an accentuated "lobular" appearance due to the proliferating mesangial cells and increased mesangial matrix. Th...
Pathology
Urinary tract
c45177f1-6e81-4167-9c4b-5a58686cb406
Destruction of ovaries prior to 7th week following fertilization results in:
Pseudohermaphroditism
Uterine agenesis
Masculinisation
None of the above
3d
multi
In females: If ovaries are destructed prior to 7 weeks then it will lead to decrease in estrogen so secondary sexual characteristics in female will not develop, and she will complain of amenorrhea. Uterus develops from mullerian duct, hence uterus will be present (i.e. option b incorrect) but underdeveloped (infantile)...
Gynaecology & Obstetrics
null
b4ede1d0-d58e-45b3-8b50-e8ec56ce60b1
A 70-year-old male patient with intentional tremor, drunken gait, and past pointing is having a lesion in which of the following structures
Basal ganglia
Pyramidal tract
Cerebellum
Thalamus
2c
single
"Most abnormalities associated with damage to the cerebellum are apparent during movement Ataxia is manifest not only in the wide-based, unsteady, "drunken" gait of patients but also in defects of the skilled movements involved in the production of speech, so that slurred, scanning speech results. Voluntary movements a...
Physiology
Nervous system
2be89eae-c77a-4a86-bd6f-e9724c97f80f
Eltrombopag is a
Erythropoietin analogue
Erythropoietin receptor agonist
Thrombopoietin analogue
GMCSF analogue
2c
single
Eltrombopag is a thrombopoietin analogue used in ITP, but carries the risk of hepatotoxicity. Lustrombopag & Avatrombopag are other thrombopoietin analogues used to prevent bleeding in patients of liver disease.
Pharmacology
null
2d6c7105-9bbd-4334-aa69-3a67f4219962
Which of the following is method of treating venous ulcer
Hilton's method
Trivex method
Bisgaard method
Tessari method
2c
single
Bisgaard method is method for treating venous ulcer.
Surgery
null
798dd92a-9a67-4fae-910a-73888fd29284
Which of the following is false about gestational hypeension?
There is a sustained rise of BP > 140/90 mmHg
Blood pressure returns to normal within 6 weeks of delivery
It is associated with lower incidence of essential hypeension in the later life as compared to pre eclampsia
Perinatal moality remains unaffected
2c
multi
Ans. is 'C i.e., It is associated with lower incidence of essential hypeension in the later life as compared to pre eclampsia Gestational hypeensionA sustained rise of blood pressure to 140/90 mm Hg or more on atleast 2 occasions 4 or more hours apa beyond the 20thweeks of pregnancyor during the first 24 hours after de...
Gynaecology & Obstetrics
null
2bae1af4-221e-4dca-98ca-9103c5a01214
Which of the following is Initial Tooth Preparation stage?
External wall finishing
Pulp protection
Convenience form
Debridement and inspection
2c
multi
Initial Tooth Preparation Stage Step 1: Initial depth and outline form. Step 2: Primary resistance form. Step 3: Primary retention form. Step 4: Convenience form. Final Tooth Preparation Stage Step 5: Removal of defective restorative material and/or soft dentin. Step 6: Pulp protection. Step 7: Secondary resistance ...
Dental
null
a35ab4c7-83c6-416b-bb3f-655c1ef7bdae
All of the following are features of ischemia in anterior choroidal aery territory except?
Hemiparesis
Hemisensory loss
Homonymous hemianopia
Predominant involvement of the anterior limb of internal capsule
3d
multi
Anterior choroidal aery Arises from the internal carotid aery. Supplies the posterior limb and genu of the internal capsule Occlusion- Contralateral hemiplegia, hemianesthesia, hypesthesia, and homonymous hemianopia. Internal capsule Blood supply ANTERIOR LIMB A.C.A. (medial striate A) + M.C.A (lateral striate A.) GENU...
Medicine
Stroke and TIA
3b9d23d8-d830-4cbc-ae02-2a99acd38340
Lens antigen are?
Neoantigen
Sequestrated antigen
Altered antigen
Cross reacting antigen
1b
single
ANSWER: (B) Sequestrated antigenREF: Ananthanarayan & Paniker 7th ed page 171, Textbook Of Medical Physiology ByKhurana 2009 ed page 207Hidden antigen or sequestrated antigen:Certain self antigens are present in the close system and never exposed to the immune system during fetal life. These are known as hidden antigen...
Ophthalmology
Miscellaneous (Lens)