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we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
there are many , many types of chemokines . and also you have these mast cells here , and these mast cells can be activated by direct contact maybe with the rusty nail . it could be from the chemokines released by some of these cells up here .
quick question , are the mast cells also called basophils ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
let 's say that they 've all been activated with a little bit of histamine . the histamine has come in so now these guys get further apart . they get further apart and the actual capillary becomes larger .
if histamine is such an important part in fighting infection like that , then why do doctors and everybody get you to take antihistamine ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so how do immunosuppressants work ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
it could be from some of the molecules released by the actual bacteria . these bacteria are also releasing different byproducts as they enter the body . and any of the above can activate the mast cells and mast cells release histamine .
does taking an antihistamine make your body 's immuno-response less effective then ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
i wo n't go into huge detail about them . let 's call this cell right here a mast cell . i 'll draw a few more mast cells .
is helper t- cell activated by mhc- ii on b cell or is a b- cell activated by an activated th cell ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so these are capillary endothelial cells , and of course , right in here , we have our blood flowing and we 'll have red blood cells in here . these are red blood cells . maybe they 're flowing in that direction .
does the inflammatory response only trigger the white blood cells that pass by the capillary ( s ) locally , because everything being released by the cells that trigger the response occur at that site or does it send a signal that releases further not discussed in the video ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
because , as i 'm going to talk about in this video , this is the first line of defense . this is the first part of the battle of our immune system . but anyway , so the histamine -- one of the things that the histamine does is it goes to the endothelial cells that line your capillaries , and it causes them to separate...
what part of the ige antibody is the peanut-specific part and what makes it so specific to peanut antigen ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so these are capillary endothelial cells , and of course , right in here , we have our blood flowing and we 'll have red blood cells in here . these are red blood cells . maybe they 're flowing in that direction .
do you lose specific b cells and t cells cells when you lose blood and therefore the ability to recognize those specific antigens ( that the b and t cells were able to identify ) ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so that 's the outside . over here , this is the interstitial fluid . that 's just a fancy word for the fluid that cells are kind of being surrounded by or that bathe cells .
i had a question about when the vasodilatation happen in the endothelial capillary 1- is their any blood will go into the interstitial fluid ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so what they actually do is -- let 's say that this right here is a neutrophil . they start kind of rolling along the wall right here . that 's called marginalization .
2- are the platelet will start to patch the the open space ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
the oxygen goes from the circulatory system to the interstitial fluid and eventually finds its way into cells . so everything is directly connected to capillaries , but capillaries play a big role in our circulatory system . so let me draw that .
is there any role of calcium ions in complement system ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so that 's the outside . over here , this is the interstitial fluid . that 's just a fancy word for the fluid that cells are kind of being surrounded by or that bathe cells .
what is the difference between the cells cytoplasm and interstitial fluid ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
and if the word histamine sounds vaguely familiar , it 's probably because you 've taken an antihistamine sometime probably in the last several months , especially during cold season . histamine is kind of one of the main actors in the inflammatory response , and when you have a cold and a runny nose and stuffy nose an...
my question is why would we want to inhibit this process ( inflammatory response ) as we do with traditional first aide treatments such as the use of ice and compression at the onset of a injury , like an ankle sprain ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so those are some skin cells in there , and then i 'm going to -- so this is the outside world right here . then amongst those skin cells , i 'll do some other cells . we 'll talk about what they do .
how could you summarize the action of both b and t cells in the process of inflammation and in the future search for abs ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
histamine is kind of one of the main actors in the inflammatory response , and when you have a cold and a runny nose and stuffy nose and all of those type of things , those are all byproducts of the inflammatory response , and anti-histamines essentially try to shut down that inflammatory response so some of those symp...
if inflammation is a good thing , why do we try and quell it down with medicine or ice etc etc ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
something has happened to me . and these are called chemokines . and chemokines are just a very general word , really , for small molecules or small proteins that cells release as a kind of signaling mechanism .
do cytokines fall under chemokines ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
it could be from some of the molecules released by the actual bacteria . these bacteria are also releasing different byproducts as they enter the body . and any of the above can activate the mast cells and mast cells release histamine .
how do phagocytes know not to attak my body ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
and as you can imagine , you have all of this fluid coming here , all of this blood is collecting here . you have all of this fluid coming into -- so not just cells that are going from our capillaries into our interstitial fluid , you 'll actually have fluid going in and that fluid that 's going in is called exudate . ...
thank you for another great video , i was wondering once the cells from inside the capillaries have entered the interstitial fluid and phagocytosed the bacteria , where do they go from there ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
i wo n't go into huge detail about them . let 's call this cell right here a mast cell . i 'll draw a few more mast cells .
how large is a single skin cell ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
the oxygen goes from the circulatory system to the interstitial fluid and eventually finds its way into cells . so everything is directly connected to capillaries , but capillaries play a big role in our circulatory system . so let me draw that .
what is the pletelets ' role ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
the oxygen goes from the circulatory system to the interstitial fluid and eventually finds its way into cells . so everything is directly connected to capillaries , but capillaries play a big role in our circulatory system . so let me draw that .
the class on capillaries by dr desai points out that no smooth muscle exists in the capillaries , so how are the capillaries expanded to open up the walls to allow passage of more material ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
on this side , they 're oxygenated . this would be arteries and then they 'd become veins as the red blood cells lose their oxygen . and of course , you might have circulating white blood cells inside of your -- obviously , in much lower quantity than your red blood cells , but just to show that they 're circulating an...
and why do surrounding lymph nodes become tender and swollen ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
i wo n't go into huge detail about them . let 's call this cell right here a mast cell . i 'll draw a few more mast cells .
what is a dendritic cell ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
this is called diapedesis or extravasation . sometimes it 's called emigration . these are all fancy words , but essentially it 's just squeezing through the walls .
does swelling also occur due the to the emigration of the neutrophils ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
will there be a permanent cure to autoimmune disease ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
and i 'm not going to go into detail here , but you actually have proteins that are flowing in your blood plasma that are normally in an inactive state , but when the inflammatory response occurs , these proteins , they get essentially activated and sometimes -- and this is all not 100 % well understood -- they become ...
what proteins are involved in the complement system ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
they move . so these chemokines get released . and this is all tremendously complicated .
- is swelling in the skin always a positive reaction after i get hurt ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so those are some skin cells in there , and then i 'm going to -- so this is the outside world right here . then amongst those skin cells , i 'll do some other cells . we 'll talk about what they do .
i know that it is because of the fluid trying to protect our bodies though ... - are b cells , helper t cells and cytotoxic cells just floating around our bodies or are they made up ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so that 's the outside . over here , this is the interstitial fluid . that 's just a fancy word for the fluid that cells are kind of being surrounded by or that bathe cells .
could someone break down the etymology of the word interstitial ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
these bacteria are also releasing different byproducts as they enter the body . and any of the above can activate the mast cells and mast cells release histamine . so you can already appreciate , i 'm doing a high-level overview , and it already is kind of complicated , but i think you get the sense of what 's going on...
taking antihistamines prevent mast cells from releasing histamine right ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
and if the word histamine sounds vaguely familiar , it 's probably because you 've taken an antihistamine sometime probably in the last several months , especially during cold season . histamine is kind of one of the main actors in the inflammatory response , and when you have a cold and a runny nose and stuffy nose an...
how does taking antihistamines affect the inflammatory response ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
let 's see what happens . so let 's say someone pokes you with this nail dipped in cow manure . so it 's got all sorts of nasty stuff on it , pathogens on it , probably has a bunch of bacteria sitting in the cow manure .
why does sal say serum instead of plasma ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
the oxygen goes from the circulatory system to the interstitial fluid and eventually finds its way into cells . so everything is directly connected to capillaries , but capillaries play a big role in our circulatory system . so let me draw that .
why is histamin such a big played ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so those are some skin cells in there , and then i 'm going to -- so this is the outside world right here . then amongst those skin cells , i 'll do some other cells . we 'll talk about what they do .
if cancer is the overgrowth of cells could n't you direct that overgrowth to parts of the body that are deficient in cells ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so this right here , this is the complement system , which is really just a set of proteins that always just floats around and they are a good kind of first line of nonspecific fight against some type of invading pathogen . so hopefully , this gives you a good sense of what is going on in the inflammatory response . an...
so its good to get an inflammatory response so that the neutrophils easier can help removing pathogens ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so hopefully , this gives you a good sense of what is going on in the inflammatory response . and as you can imagine , you have all of this fluid coming here , all of this blood is collecting here . you have all of this fluid coming into -- so not just cells that are going from our capillaries into our interstitial flu...
at 1 is n't an `` exudate '' the fluid that comes out of the blood vessels ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
it could be from some of the molecules released by the actual bacteria . these bacteria are also releasing different byproducts as they enter the body . and any of the above can activate the mast cells and mast cells release histamine .
is n't vasodilation also what happens when your body need to expel heat ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
what makes a swollen wound throb ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so those are some skin cells in there , and then i 'm going to -- so this is the outside world right here . then amongst those skin cells , i 'll do some other cells . we 'll talk about what they do .
so is this true , or can the specific immunity cells attack pathogens everywhere in the body ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
what 's happening at a cellular level ? because , really , the inflammatory response is essentially the initial field of battle of our immune system . our first line of defense is our skin or the fluids on the outside of our skin or the mucous membranes , but the inflammatory response is what happens when something get...
if the inflammatory response is a good thing because it allows your immune system to fight against pathogens , then why are we always taught to try to minimise it or get rid of it as soon as we can ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so these are capillary endothelial cells , and of course , right in here , we have our blood flowing and we 'll have red blood cells in here . these are red blood cells . maybe they 're flowing in that direction .
what is the difference between bood type a and blood type c and blood type o positive ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
i did n't pick cow manure at random . it 's probably a good source of bacteria . so as soon as it pierces the first line of defense , as soon as it pierces your skin , a couple of things are going to happen .
why is good to take an ice bath to help with the muscles ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
i 'll draw a couple of dendritic cells and these are also the ones that were really good at activating helper t-cells . they 're called dendritic cells . they have no relation to the nervous system .
the dendritic cells in the skin , are they also called langerhans cells ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
i wo n't go into huge detail about them . let 's call this cell right here a mast cell . i 'll draw a few more mast cells .
the process of a b-cell becoming a effector or a memory cell , does that happen in the lymfenodes ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so those are some skin cells in there , and then i 'm going to -- so this is the outside world right here . then amongst those skin cells , i 'll do some other cells . we 'll talk about what they do .
and do the t-cells and b-cells come immediately at the location of the wound during the inflammatory respons ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so let 's say someone takes a nail , dips it in some cow manure , and then pokes you with that nail . let 's see what happens . so let 's say someone pokes you with this nail dipped in cow manure .
what happens if any phagocyte escape from phagosomes than il1b will release or not ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
i 'll draw a couple of dendritic cells and these are also the ones that were really good at activating helper t-cells . they 're called dendritic cells . they have no relation to the nervous system .
is n't there any lymph nodes around for dendritic cells to present the antigens ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so these are capillary endothelial cells , and of course , right in here , we have our blood flowing and we 'll have red blood cells in here . these are red blood cells . maybe they 're flowing in that direction .
during vasodilation , when the endothelial cells spread out from eachother allowing white blood cells to get outside of the capillary , why do n't red blood cells also do this ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so these are capillary endothelial cells , and of course , right in here , we have our blood flowing and we 'll have red blood cells in here . these are red blood cells . maybe they 're flowing in that direction .
i thought that white blood cells were larger than red blood cells , so if they can go through , certainly the red can too ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so i 'm going to do a cross-section . so those are some skin cells in there , and then i 'm going to -- so this is the outside world right here . then amongst those skin cells , i 'll do some other cells . we 'll talk about what they do .
how does the oxygen get to the cells in the body sense they are not right up against the capillaries ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
on this side , they 're oxygenated . this would be arteries and then they 'd become veins as the red blood cells lose their oxygen . and of course , you might have circulating white blood cells inside of your -- obviously , in much lower quantity than your red blood cells , but just to show that they 're circulating an...
and are n't arteries and veins never truly veins and arteries because they give oxygen to the hull body ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so these are capillary endothelial cells , and of course , right in here , we have our blood flowing and we 'll have red blood cells in here . these are red blood cells . maybe they 're flowing in that direction .
when gaps are formed on the endothelial cells due to inflammation , other than the neutrophils does n't blood or red blood corpuscles move through the gap and get mixed with the interstitial fluid ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
they 're going to phagocytose some of these bacteria and start eating up , and maybe even some damaged cells up here . and so that 's what you want to happen . that 's why i said this is the field of battle .
could all those symptoms happen at once ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
these bacteria are also releasing different byproducts as they enter the body . and any of the above can activate the mast cells and mast cells release histamine . so you can already appreciate , i 'm doing a high-level overview , and it already is kind of complicated , but i think you get the sense of what 's going on...
is histamine released only by mast cells or do any other cells also do the same ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
i wo n't go into huge detail about them . let 's call this cell right here a mast cell . i 'll draw a few more mast cells .
is the function of the capillary endothelial cell to allow for gaseous exchange ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so those are some skin cells in there , and then i 'm going to -- so this is the outside world right here . then amongst those skin cells , i 'll do some other cells . we 'll talk about what they do .
0 , do the mast cells and dendritic cells hang out in the skin or in the subcutaneous system ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
instead of just drawing them as tubes , i 'm actually going to draw the cells of our circulatory system . so let 's say that this down here -- these are the endothelial cells of our capillaries . so these are literally the cells that make up the walls of our capillaries .
sal said histamine dilate the endothelial of capillaries sould't it be the dilation of both exothelial and endothelial ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
everything is in cross-section . so these are capillary endothelial cells , and of course , right in here , we have our blood flowing and we 'll have red blood cells in here . these are red blood cells . maybe they 're flowing in that direction .
was just wondering , if the nail punctures the skin and causes bleeding , i 'm assuming the capillary endothelial layer is broken too and red blood cells/plasma come out , then platelets come and accumulate right ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
these bacteria are also releasing different byproducts as they enter the body . and any of the above can activate the mast cells and mast cells release histamine . so you can already appreciate , i 'm doing a high-level overview , and it already is kind of complicated , but i think you get the sense of what 's going on...
then does the same inflammatory response happen with the neutrophils and mast cells releasing histamine ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
everything is in cross-section . so these are capillary endothelial cells , and of course , right in here , we have our blood flowing and we 'll have red blood cells in here . these are red blood cells .
what about restoring the epithelial and capillary endothelial cells ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so those are some skin cells in there , and then i 'm going to -- so this is the outside world right here . then amongst those skin cells , i 'll do some other cells . we 'll talk about what they do .
doesnt the phagocytes and b cells and t cells travel in the lymphatic system ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
let 's say that they 've all been activated with a little bit of histamine . the histamine has come in so now these guys get further apart . they get further apart and the actual capillary becomes larger .
where do check point inhibitors come in ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
what 's happening at a cellular level ? because , really , the inflammatory response is essentially the initial field of battle of our immune system . our first line of defense is our skin or the fluids on the outside of our skin or the mucous membranes , but the inflammatory response is what happens when something get...
why is the inflammatory response under the innate immune system if it involves b and t cells - ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
and of course , this is a cross-section . if i were to -- i would draw it as a tube somehow . it 's not like it 's a sandwich . it 's actually a tube .
considering a novel virus like mers-cov , would you recommend a cocktail of interferon , ribavirin , and plasma from a previously infected human ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
they kind of hang out near areas that might interface with the outside world . i 'll draw a couple of dendritic cells and these are also the ones that were really good at activating helper t-cells . they 're called dendritic cells .
in terms of `` attraction '' , are neutrophils the only ones that are stimulated by these chemicals and then cause other cells to come along ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
and as you can imagine , you have all of this fluid coming here , all of this blood is collecting here . you have all of this fluid coming into -- so not just cells that are going from our capillaries into our interstitial fluid , you 'll actually have fluid going in and that fluid that 's going in is called exudate . ...
is n't interstitial fluid called tissue fluid ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so these are capillary endothelial cells , and of course , right in here , we have our blood flowing and we 'll have red blood cells in here . these are red blood cells . maybe they 're flowing in that direction .
i always thought blood only has 3 things-wbc ( does the fighting n immunity thing ) rbc ( carry o2 ) and platelets ( for coagulation ) and serum fibrinogen etc other little things ... .but for immunity it was just wbc ( its 5 tyes ... neutrophills basophills esoinophills monocytes and lymphocytes ) now m not comfortabl...
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
they want to move in the direction that there 's more of these chemicals . and now that the space between these capillary cells have gotten further apart , they can get through . so what they actually do is -- let 's say that this right here is a neutrophil .
so the capillary endothelial cells `` opens up '' to let the `` soldiers '' though the artery wall , if the `` doors '' are `` open '' does this mean that the phagocytes can get in the bloodstream and get elsewhere in the body or cause more damage ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
and if the word histamine sounds vaguely familiar , it 's probably because you 've taken an antihistamine sometime probably in the last several months , especially during cold season . histamine is kind of one of the main actors in the inflammatory response , and when you have a cold and a runny nose and stuffy nose an...
is the swelling , the pain and everything else from a bee sting an inflammatory response ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
but anyway , so the histamine -- one of the things that the histamine does is it goes to the endothelial cells that line your capillaries , and it causes them to separate away from each other and make the actual capillaries larger . this is called vasodilation . let 's say that they 've all been activated with a little...
how does the vasodilation induced by histamin work ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
something has happened to me . and these are called chemokines . and chemokines are just a very general word , really , for small molecules or small proteins that cells release as a kind of signaling mechanism .
are chemokines also known as cytokines ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so these are capillary endothelial cells , and of course , right in here , we have our blood flowing and we 'll have red blood cells in here . these are red blood cells . maybe they 're flowing in that direction .
why do the white blood cells follow the chemical thingys ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
so you can already appreciate , i 'm doing a high-level overview , and it already is kind of complicated , but i think you get the sense of what 's going on . and if the word histamine sounds vaguely familiar , it 's probably because you 've taken an antihistamine sometime probably in the last several months , especial...
besides taking an antihistamine is there anything to take to reduce the itchiness and swelling ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
but anyway , so the histamine -- one of the things that the histamine does is it goes to the endothelial cells that line your capillaries , and it causes them to separate away from each other and make the actual capillaries larger . this is called vasodilation . let 's say that they 've all been activated with a little...
how does this vasodilation prevent disease by absorbing the viruses ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
these bacteria are also releasing different byproducts as they enter the body . and any of the above can activate the mast cells and mast cells release histamine . so you can already appreciate , i 'm doing a high-level overview , and it already is kind of complicated , but i think you get the sense of what 's going on...
what are the mast cells ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
that 's why i said this is the field of battle . at the same time , your dendritic cells , other phagocytes , they will eat up the viruses and then they 'll present them on their surfaces . and it 's not just neutrophils that are coming in .
doesnt the viruses or bacterias manage to slip away ?
we 've all had cuts on our finger or wherever else on our body , and immediately that part of the body gets a little bit of redness , a little bit of swelling , some heat maybe , and , of course , there 'll be some pain associated with what 's going on there . and in general , this set of symptoms that we experience , ...
histamine is kind of one of the main actors in the inflammatory response , and when you have a cold and a runny nose and stuffy nose and all of those type of things , those are all byproducts of the inflammatory response , and anti-histamines essentially try to shut down that inflammatory response so some of those symp...
so it begs the explainer : how does inflammation become the secret killer ?
- [ teacher ] not only are there many different kinds of energies , but both objects , and systems of objects , can have energy . once they have that energy , they can transfer it to another system or object or that energy could transform to a different type of energy inside that system . when energy gets transferred ,...
my negative area is negative nine . my positive area , so far , is positive four . if i continue on to the six meter mark , i 've pick up another positive four joules of work since the height of this rectangle is four and the width is one meter , which means we 're almost there .
does the direction of the velocities not matter because the squares will make them positive anyways ?
- [ teacher ] not only are there many different kinds of energies , but both objects , and systems of objects , can have energy . once they have that energy , they can transfer it to another system or object or that energy could transform to a different type of energy inside that system . when energy gets transferred ,...
if the force on the object has a component in the opposite direction of the motion , the work done by that force would be negative and it would take away the object 's energy . and , if the force on an object is perpendicular to the motion of the object , that force does zero work on the object . it neither gives the o...
when a force is perpendicular to the direction of motion , why is there 0 work being done on the object ?
- [ teacher ] not only are there many different kinds of energies , but both objects , and systems of objects , can have energy . once they have that energy , they can transfer it to another system or object or that energy could transform to a different type of energy inside that system . when energy gets transferred ,...
it decreases because now the earth is outside of our system and the work that it is doing on the box is external work and it 's taking away energy from the box . what does work mean ? in physics , work is the amount of energy transferred from one system , or object , to another .
does that mean that , if the final velocity of that object were -4 m/s ( still going in the same direction ) as opposed to 4 m/s as was seen in the video , the net work would still be the same ?
- [ teacher ] not only are there many different kinds of energies , but both objects , and systems of objects , can have energy . once they have that energy , they can transfer it to another system or object or that energy could transform to a different type of energy inside that system . when energy gets transferred ,...
what happens to the total mechanical energy in this case ? well , the only energy that i 've got in my system , now , is kinetic energy and since that kinetic energy decreased , the total mechanical energy of the box , as a system , decreases . how does it decrease ?
should n't it be 1/2mv^2 - mgh because the box starts off with mgh and ends with kinetic energy ?
- [ teacher ] not only are there many different kinds of energies , but both objects , and systems of objects , can have energy . once they have that energy , they can transfer it to another system or object or that energy could transform to a different type of energy inside that system . when energy gets transferred ,...
how does it decrease ? it decreases because now the earth is outside of our system and the work that it is doing on the box is external work and it 's taking away energy from the box . what does work mean ? in physics , work is the amount of energy transferred from one system , or object , to another . in other words ,...
how does the earth perform work ( mgh ) on one of your incline problems if the box was not moving in the direction of gravity ?
- [ teacher ] not only are there many different kinds of energies , but both objects , and systems of objects , can have energy . once they have that energy , they can transfer it to another system or object or that energy could transform to a different type of energy inside that system . when energy gets transferred ,...
if the force on the object has a component in the opposite direction of the motion , the work done by that force would be negative and it would take away the object 's energy . and , if the force on an object is perpendicular to the motion of the object , that force does zero work on the object . it neither gives the o...
when a force is perpendicular to the direction of motion , why is there 0 work being done on the object ?
: we 'll start with a carboxylic acid that has at least one alpha proton on it . right here is our alpha carbon . we can see this reaction we 're going to substitute in . instead of a hydrogen in the alpha position , we 're going to have a bromine at the alpha position . here 's your alpha position . this is alpha sub...
we already know what the product looks like for the hvz reaction , so we draw in our carboxylic acid and we know there 's going to be a bromine substituting at the alpha position and there 's still a hydrogen bonded to this alpha position here . thinking about this alpha carbon right here , there are four different sub...
why does : nh3 attacks the alpha carbon instead of the carbonyl carbon which seems more electrophilic ?
: we 'll start with a carboxylic acid that has at least one alpha proton on it . right here is our alpha carbon . we can see this reaction we 're going to substitute in . instead of a hydrogen in the alpha position , we 're going to have a bromine at the alpha position . here 's your alpha position . this is alpha sub...
if these electrons in the oxygen move into here to form the carbonyl , these electrons in blue could attack this bromine and then these electrons in red would come off onto the bromine on the right to form the bromide anion . let 's go ahead and draw what we would make . we would have our r group , we would have this c...
would heat be required to make the amine act as a nucleophile ?
: we 'll start with a carboxylic acid that has at least one alpha proton on it . right here is our alpha carbon . we can see this reaction we 're going to substitute in . instead of a hydrogen in the alpha position , we 're going to have a bromine at the alpha position . here 's your alpha position . this is alpha sub...
we already know what the product looks like for the hvz reaction , so we draw in our carboxylic acid and we know there 's going to be a bromine substituting at the alpha position and there 's still a hydrogen bonded to this alpha position here . thinking about this alpha carbon right here , there are four different sub...
when you describe how adding water causes the alpha bromo acyl bromide to turn into the product , why does n't water substitute at the alpha carbon as well ?
so i have got this block of wood here that has a mass of 5 kilograms and it is sitting on some dirt and we are near the surface of the earth and the coefficient of static friction between this type of wood and this type of dirt is 0.60 and the coefficient of kinetic friction between this type of wood and this type of d...
and that 's why this block does not accelerate upwards or downwards so what we have is the budge the magnitude of the budging force , needs to be equal to , over the magnitude of the normal force well this thing right over here is going to be 49 newtons is equal to 0.60 or we could say that the magnitude of the budging...
what happens if the object is in between two walls and is going downward ?
so i have got this block of wood here that has a mass of 5 kilograms and it is sitting on some dirt and we are near the surface of the earth and the coefficient of static friction between this type of wood and this type of dirt is 0.60 and the coefficient of kinetic friction between this type of wood and this type of d...
so the first thing you might realize is if there is no friction if this was a completely frictionless boundary and there is no air resistance , we are assuming that there is no air resistance in this example that in this dimension , in the horizontal dimension there would only be one force here , this 100 n force it wo...
how could we find normal force with two static frictions of 0.8 and 0.6 ?
so i have got this block of wood here that has a mass of 5 kilograms and it is sitting on some dirt and we are near the surface of the earth and the coefficient of static friction between this type of wood and this type of dirt is 0.60 and the coefficient of kinetic friction between this type of wood and this type of d...
so i have got this block of wood here that has a mass of 5 kilograms and it is sitting on some dirt and we are near the surface of the earth and the coefficient of static friction between this type of wood and this type of dirt is 0.60 and the coefficient of kinetic friction between this type of wood and this type of d...
how does the duration of the force being applied affect the acceleration ?
so i have got this block of wood here that has a mass of 5 kilograms and it is sitting on some dirt and we are near the surface of the earth and the coefficient of static friction between this type of wood and this type of dirt is 0.60 and the coefficient of kinetic friction between this type of wood and this type of d...
so the first thing you might realize is if there is no friction if this was a completely frictionless boundary and there is no air resistance , we are assuming that there is no air resistance in this example that in this dimension , in the horizontal dimension there would only be one force here , this 100 n force it wo...
why is static friction equal to budging force/normal force ?
so i have got this block of wood here that has a mass of 5 kilograms and it is sitting on some dirt and we are near the surface of the earth and the coefficient of static friction between this type of wood and this type of dirt is 0.60 and the coefficient of kinetic friction between this type of wood and this type of d...
we have 100 n to the right ; we have 26.95 to the left 100 minus 26.95 100 n that i 'm applying to the right - 26.95 n which is the force of friction to the left always acting against us means that there 's a net force to the right of 73.05 so once we 're moving , we have a net force to the right of 73.05 n this is the...
what is the kinetic friction and static friction ?
so i have got this block of wood here that has a mass of 5 kilograms and it is sitting on some dirt and we are near the surface of the earth and the coefficient of static friction between this type of wood and this type of dirt is 0.60 and the coefficient of kinetic friction between this type of wood and this type of d...
so i have got this block of wood here that has a mass of 5 kilograms and it is sitting on some dirt and we are near the surface of the earth and the coefficient of static friction between this type of wood and this type of dirt is 0.60 and the coefficient of kinetic friction between this type of wood and this type of d...
if the force is only applied once and not constantly , does the static friction affect the object 's acceleration throughout its entire motion ?
so i have got this block of wood here that has a mass of 5 kilograms and it is sitting on some dirt and we are near the surface of the earth and the coefficient of static friction between this type of wood and this type of dirt is 0.60 and the coefficient of kinetic friction between this type of wood and this type of d...
so we can start using the coefficient of kinetic friction it 's the ratio between that and the magnitude of the force of contact between this block and the floor or ground here and the magnitude of that force of contact is the same thing as the normal force that the ground is applying on the block the magnitude of the ...
could someone give me some examples of static friction ?
so i have got this block of wood here that has a mass of 5 kilograms and it is sitting on some dirt and we are near the surface of the earth and the coefficient of static friction between this type of wood and this type of dirt is 0.60 and the coefficient of kinetic friction between this type of wood and this type of d...
so i have got this block of wood here that has a mass of 5 kilograms and it is sitting on some dirt and we are near the surface of the earth and the coefficient of static friction between this type of wood and this type of dirt is 0.60 and the coefficient of kinetic friction between this type of wood and this type of d...
could someone please explain what the budging force is ?
so i have got this block of wood here that has a mass of 5 kilograms and it is sitting on some dirt and we are near the surface of the earth and the coefficient of static friction between this type of wood and this type of dirt is 0.60 and the coefficient of kinetic friction between this type of wood and this type of d...
we have 100 n to the right ; we have 26.95 to the left 100 minus 26.95 100 n that i 'm applying to the right - 26.95 n which is the force of friction to the left always acting against us means that there 's a net force to the right of 73.05 so once we 're moving , we have a net force to the right of 73.05 n this is the...
what 's the difference between static friction and kinetic friction ?
so i have got this block of wood here that has a mass of 5 kilograms and it is sitting on some dirt and we are near the surface of the earth and the coefficient of static friction between this type of wood and this type of dirt is 0.60 and the coefficient of kinetic friction between this type of wood and this type of d...
so the first thing you might realize is if there is no friction if this was a completely frictionless boundary and there is no air resistance , we are assuming that there is no air resistance in this example that in this dimension , in the horizontal dimension there would only be one force here , this 100 n force it wo...
does the amount of force needed to overcome friction change at all when the contact surface area changes ?
so i have got this block of wood here that has a mass of 5 kilograms and it is sitting on some dirt and we are near the surface of the earth and the coefficient of static friction between this type of wood and this type of dirt is 0.60 and the coefficient of kinetic friction between this type of wood and this type of d...
i can draw them whatever , but remember this is acting on the object if we want to be precise , we can show it on the center of mass because we can view all of these atoms as one collective object but anyway , what is the net force now ? we have 100 n to the right ; we have 26.95 to the left 100 minus 26.95 100 n that ...
why does n't friction increase with increase in velocity of the block ?
so i have got this block of wood here that has a mass of 5 kilograms and it is sitting on some dirt and we are near the surface of the earth and the coefficient of static friction between this type of wood and this type of dirt is 0.60 and the coefficient of kinetic friction between this type of wood and this type of d...
we have 100 n to the right ; we have 26.95 to the left 100 minus 26.95 100 n that i 'm applying to the right - 26.95 n which is the force of friction to the left always acting against us means that there 's a net force to the right of 73.05 so once we 're moving , we have a net force to the right of 73.05 n this is the...
does it remain constant even if the block keeps moving for a long time ?
so i have got this block of wood here that has a mass of 5 kilograms and it is sitting on some dirt and we are near the surface of the earth and the coefficient of static friction between this type of wood and this type of dirt is 0.60 and the coefficient of kinetic friction between this type of wood and this type of d...
we have 100 n to the right ; we have 26.95 to the left 100 minus 26.95 100 n that i 'm applying to the right - 26.95 n which is the force of friction to the left always acting against us means that there 's a net force to the right of 73.05 so once we 're moving , we have a net force to the right of 73.05 n this is the...
does it instantaneously go from 14.1 m/s/s to 14.61 m/s/s ?
so i have got this block of wood here that has a mass of 5 kilograms and it is sitting on some dirt and we are near the surface of the earth and the coefficient of static friction between this type of wood and this type of dirt is 0.60 and the coefficient of kinetic friction between this type of wood and this type of d...
so i have got this block of wood here that has a mass of 5 kilograms and it is sitting on some dirt and we are near the surface of the earth and the coefficient of static friction between this type of wood and this type of dirt is 0.60 and the coefficient of kinetic friction between this type of wood and this type of d...
is there jerk involved ( a change in acceleration over time ex : m/s/s/s ) ?