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Direct differentiation of ears and tassels from cultured shoot apices of maize.
In vitro morphogenesis of inflorescences from the cultured corn seedling shoot tips was obtained on modified Murashige and Skoog (MS) medium in complete darkness. Some shoot tip meristems excised from seedlings of inbred line 515, inbred line 8112 and their filial generations would directly give rise to florets on modi...
18,726,493
Reduction of lesion growth rate of late blight plant disease in transgenic potato expressing harpin protein.
Using harpin protein gene from apple fire blight pathogen Erwinia amylovora and potato prp1-1 promoter as main DNA elements, the feasibility of using pathogen infection-induced hypersensitive response was explored as a new strategy of engineering fungal disease resistance. Three plant transformation vectors were constr...
18,726,504
A novel recombinant adeno-associated virus vector packaging system with HSV-1 amplicon providing helper functions.
A novel packaging system for producing recombinant adeno-associated virus (rAAV) vector was described. Instead of the conventional method for rAAV production by two-plasmid co-transfection followed by superinfection with adenovirus 5, an HSV-1 amplicon system expressing AAV-2 rep and cap genes from their native promote...
18,726,509
Characteristics of photosensitization of Pheophorbide a in liposomal media.
Pheophorbide a (PPa), a decomposition product of chlorophyll a, is a photosensitizer. The photosensitization mechanisms (Type I and Type 11) of PPa in simple buffer solutions and in buffer solutions containing double-layered DPPC liposomes have been studied using techniques of ESR, spin-trapping, spin-counteraction and...
18,726,510
Assistive devices: usage in patients with rheumatoid arthritis.
We describe the usage of various assistive devices and identify factors associated with usage in patients with rheumatoid arthritis (RA). A cross-sectional, multicentre study was performed in three outpatient rheumatology clinics in the Netherlands. Two hundred forty patients with RA participated in the study. The main...
18,726,549
A point-prevalence study for MRSA in a German university hospital to identify patients at risk and to evaluate an established admission screening procedure.
Due to the enormous increase in the number of MRSA-patients, in July 2004, an extended admission screening protocol was implemented in ICUs and surgical wards at Hannover Medical School. In 2005, a point-prevalence study (also known as a cross-sectional study) was conducted to determine the prevalence of MRSA and Panto...
18,726,552
Isolation and characterization of a low phytic acid rice mutant reveals a mutation in the rice orthologue of maize MIK.
Using a forward genetics approach, we isolated two independent low phytic acid (lpa) rice mutants, N15-186 and N15-375. Both mutants are caused by single gene, recessive non-lethal mutations, which result in approximately 75% (N15-186) and 43% (N15-375) reductions in seed phytic acid (inositol hexakisphosphate). High-p...
18,726,583
Comparative study and expression analysis of the interferon gamma gene locus cytokines in Xenopus tropicalis.
Using bioinformatics approach, the genome locus containing interleukin (IL)-22, IL-26, and interferon gamma (IFN-gamma) genes has been identified in the amphibian, Xenopus tropicalis. Like that in other vertebrates such as fish, birds, and mammals, the Xenopus IL-22, IL-26, and IFN-gamma are clustered in the same chrom...
18,726,591
Anticipatory control of impending postural perturbation in elite springboard divers.
Among athletes, elite springboard divers (ED) should develop an optimal anticipatory control of postural stability, as a result of specific training. Postural strategies of ED and healthy subjects (HS) while expecting an impending perturbation were compared. The mean center of pressure (COP) position was analyzed durin...
18,726,612
The accuracy of sentinel lymph node biopsy in the treatment of multicentric invasive breast cancer using a subareolar injection of tracer.
The aim of this study was to evaluate the feasibility and the accuracy of sentinel lymph node biopsy in multicentric breast cancer (MBC) performed by means of a subareolar (SA) injection of both 99Tc-labeled human albumin colloid and lymphazurin. Between January 2002 and October 2007, 34 patients with MBC with clinical...
18,726,647
Massive pulmonary embolism immediately diagnosed by transthoracic echocardiography and treated with tenecteplase fibrinolysis.
We report the case of a 75-year-old woman with new onset dyspnoea, hypotension, and right bundle branch block. Transthoracic echocardiography (TTE) showed a thrombus in the right pulmonary artery and acute pulmonary embolism was diagnosed. The patient immediately underwent fibrinolysis with tenecteplase, with prompt re...
18,726,674
Research on transition to adulthood: building the evidence base to inform services and supports for youth and young adults with serious mental health disorders.
Since the mid-1990s, research has established a clear picture of the poor real-life outcomes achieved by transition-age youth and young adults who have been diagnosed with a serious mental health disorder. The purpose of this article is to: (1) introduce the reader to the other eight articles in this special issue on T...
18,726,695
Biological effects of FoxJ2 over-expression.
As reported previously, we have extensively studied FoxJ2, a member of the Fork Head transcription factors family. While the biochemical and functional structures of this transcription factor are well understood, its biological function remains unknown. Here, we present data that address this point using transgenic mou...
18,726,704
Risk factors for Mycobacterium avium subspecies paratuberculosis in Fars province (Southern Iran) dairy herds.
A cross-sectional study was conducted from March to August 2006 in dairy herds in Fars province, southern Iran to determine the herd-level risk factors for infection with Mycobacterium avium subspecies paratuberculosis (MAP). Statistical analysis using multivariable logistic regression showed that contamination of udde...
18,726,705
Observed versus estimated IQ as an index of malingering in traumatic brain injury: classification accuracy in known groups.
This study examined the classification accuracy of observed WAIS-III VIQ, PIQ, and FSIQ minus Barona-estimate differential scores in the detection of Malingered Neurocognitive Dysfunction (MND) in Traumatic Brain Injury (TBI) using a known-groups design. Two hundred eleven TBI patients were assigned to one of three gro...
18,726,736
Executive functions in a Turkish sample: associations with demographic variables and normative data.
Attention and executive functions are affected by demographic factors. The study presented in this paper examines the effects of education, gender, and age on the scores of the Color Trail Test (CTT) (D'Elia, Satz, Uchiyama, & White, 1999) and the Visual Verbal Test (VVT) (Feldman & Drasgow, 1959), which are co...
18,726,740
Administration frequencies of WAIS-III supplementary and optional subtests of board-certified clinical neuropsychologists.
The present investigation surveyed board-certified clinical neuropsychologists in four geographic regions of the United States regarding their administration practices of the WAIS-III supplementary subtests (Letter-Number Sequencing, Symbol Search), optional subtest (Object Assembly), and optional procedures (Digit Sym...
18,726,741
Evaluation of a fully automated method to measure the critical removal stress of adult barnacles.
A computer-controlled force gauge designed to measure the adhesive strength of barnacles on test substrata is described. The instrument was evaluated with adult barnacles grown in situ on Silastic T2(R)-coated microscope slides and epoxy replicas adhered to the same substratum with synthetic adhesive. The force per uni...
18,726,746
Can movie theater advertisements promote health behaviors? Evaluation of a flu vaccination pilot campaign.
As part of a multimedia campaign to promote annual influenza vaccination, three slides were shown as part of the slide show of advertisements prior to the beginning of previews in movie theaters in San Diego County. Intercept surveys were conducted following the movie. The primary target groups for the campaign were ad...
18,726,815
Exploring the time course of semantic interference and associative priming in the picture-word interference task.
The picture-word interference (PWI) task is a widely used technique for exploring effects of semantic context on lexical access. In this task, printed words are superimposed over pictures to be named, with the timing of the interfering word relative to the picture systematically manipulated. Two experiments (N = 24 adu...
18,726,823
Modulation of 11beta-hydroxysteroid dehydrogenase expression by bombesin: a possible mechanism for glucocorticoid resistance in androgen independent prostate cancer.
Treatment with glucocorticoids is one of a limited number of options for androgen independent prostate cancer. Neuroendocrine differentiation has been shown to contribute to androgen-independent prostate cancer progression. To study the potential link between neuroendocrine differentiation and the glucocorticoid action...
18,726,827
Rapid reduction of liver steatosis in omega3-depleted rats injected with a novel lipid emulsion.
The bolus intravenous administration of a novel medium-chain triglyceride: fish oil emulsion (MCT:FO) to normal subjects was recently found to increase within 60 min the amount of long-chain polyunsaturated omega3 fatty acids ( omega3) in platelet and leukocyte phospholipids and, hence, was proposed as a tool to preven...
18,726,832
A case-control comparison of the effectiveness of betamethasone to prevent neonatal morbidity and mortality in preterm twin and singleton pregnancies.
We compared the effectiveness of antenatal betamethasone for the prevention of neonatal morbidity and mortality in preterm twin and singleton gestations. We conducted a case-control study of women with twin versus singleton gestations who received betamethasone for risk of prematurity in a university-affiliated, commun...
18,726,837
Drugs, carrier solutions and temperature in hyperthermic intraperitoneal chemotherapy.
At the Fifth International Workshop on Peritoneal Surface Malignancy, in Milan, the consensus on technical aspects of cytoreductive surgery (CRS) for peritoneal surface malignancy was obtained through the Delphi process. Conflicting points concerning drugs, carrier solution and optimal temperature for hyperthermic intr...
18,726,886
Expression of TSLC1, a candidate tumor suppressor gene mapped to chromosome 11q23, is downregulated in unfavorable neuroblastoma without promoter hypermethylation.
Although it has been well documented that loss of human chromosome 11q is frequently observed in primary neuroblastomas, the smallest region of overlap (SRO) has not yet been precisely identified. Previously, we performed array-comparative genomic hybridization (array-CGH) analysis for 236 primary neuroblastomas to sea...
18,726,896
Neural correlates of personally familiar faces: parents, partner and own faces.
Investigations of the neural correlates of face recognition have typically used old/new paradigms where subjects learn to recognize new faces or identify famous faces. Familiar faces, however, include one's own face, partner's and parents' faces. Using event-related fMRI, we examined the neural correlates of these pers...
18,726,910
Pseudohomophone effects provide evidence of early lexico-phonological processing in visual word recognition.
Previous research using event-related brain potentials (ERPs) suggested that phonological processing in visual word recognition occurs rather late, typically after semantic or syntactic processing. Here, we show that phonological activation in visual word recognition can be observed much earlier. Using a lexical decisi...
18,726,911
Risk prediction of fever in neutropenia in children with cancer: a step towards individually tailored supportive therapy?
Fever in severe chemotherapy-induced neutropenia (FN) is the most frequent manifestation of a potentially lethal complication of current intensive chemotherapy regimens. This study aimed at establishing models predicting the risk of FN, and of FN with bacteremia, in pediatric cancer patients. In a single-centre cohort ...
18,726,920
Screening for trisomy 18 by maternal age, fetal nuchal translucency, free beta-human chorionic gonadotropin and pregnancy-associated plasma protein-A.
To derive a model and examine the performance of first-trimester screening for trisomy 18 by maternal age, fetal nuchal translucency (NT) thickness, and maternal serum free beta-human chorionic gonadotropin (beta-hCG) and pregnancy-associated plasma protein-A (PAPP-A). Prospective combined screening for trisomy 21 was ...
18,726,925
Cell-free synthesis of functional proteins using transcription/translation machinery entrapped in silica sol-gel matrix.
Herewith we report the encapsulation of functional protein synthesis machinery in a silica sol-gel matrix. When the sol-gel reaction using alkoxysilane monomers was carried out in the presence of Escherichia coli cell extract, macromolecular protein synthesis machinery in the cell extract was successfully immobilized w...
18,726,964
Towards in silico liquid crystals. Realistic transition temperatures and physical properties for n-cyanobiphenyls via molecular dynamics simulations.
We study the important n-cyanobiphenyl (with n= 4-8) series of mesogens, using modelling and molecular dynamics simulations. We are able to obtain spontaneously ordered nematics upon cooling isotropic samples of 250 molecules. By using the united-atom force field developed herein, we show that the experimental isotropi...
18,726,965
Sonographic assessment of uterine and ovarian development in normal girls aged 1 to 12 years.
To provide normal references of sonographic uterine and ovarian size in girls aged 1-12 years. Ninety-nine girls were enrolled in the study (mean age +/- SD, 6.9 +/- 2.4 years [range, 1-12 years]). Pubertal status was classified according to Tanner staging, whereas for height and weight assessment a standard stadiomete...
18,726,968
Apigenin suppresses insulin-like growth factor I receptor signaling in human prostate cancer: an in vitro and in vivo study.
Deregulation of insulin-like growth factor (IGF)-I/IGF-IR signaling has been implicated in the development and progression of prostate cancer. Agents that can suppress the mitogenic activity of the IGF/IGF-IR growth axis may be of preventive or therapeutic value. We have previously demonstrated that apigenin, a plant f...
18,726,972
Alternariol acts as a topoisomerase poison, preferentially affecting the IIalpha isoform.
Alternariol (AOH), a mycotoxin formed by Alternaria alternata, has been reported to possess genotoxic properties. However, the underlying mechanism of action is unclear. Here, we tested the hypothesis that interactions with DNA-topoisomerases play a role in the DNA-damaging properties of AOH. First we compared DNA-dama...
18,727,009
Fermentative butanol production by Clostridia.
Butanol is an aliphatic saturated alcohol having the molecular formula of C(4)H(9)OH. Butanol can be used as an intermediate in chemical synthesis and as a solvent for a wide variety of chemical and textile industry applications. Moreover, butanol has been considered as a potential fuel or fuel additive. Biological pro...
18,727,018
In vivo nonmelanoma skin cancer diagnosis using Raman microspectroscopy.
Nonmelanoma skin cancers, including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), are the most common skin cancers, presenting nearly as many cases as all other cancers combined. The current gold-standard for clinical diagnosis of these lesions is histopathologic examination, an invasive, time-consuming...
18,727,020
Voxel-shift and interpolation for hadamard-encoded MR images.
Although Fourier gradient phase-encoding and Hadamard radio-frequency encoding are two established spatial MR localization techniques, the absence of voxel-shift and interpolation postprocessing algorithms for the latter has always placed it at a discouraging disadvantage. This article presents a method for voxel-shift...
18,727,037
Hippocampal levels of phosphorylated protein kinase A (phosphor-S96) are linked to spatial memory enhancement by SGS742.
Cognitive enhancement by the GABA (B) receptor antagonist SGS742 has been well-documented, but mechanisms of action are not fully elucidated. Previous work has proposed involvement of somatostatin-14 and protein kinase C in cognitive enhancement; phospho-protein kinase A (p-PKA), fyn, and phospho-fyn are known signalin...
18,727,045
The protein kinase C phosphorylation site on GAP-43 differentially regulates information storage.
Protein kinase C (PKC) is known to regulate phosphorylation of substrates such as MARCKS, GAP-43, and the NMDA receptor, all of which have been linked to synaptic plasticity underlying information storage processes. Here we report on three transgenic mice isoforms differentiated both by mutation of the PKC site on GAP-...
18,727,047
The human hippocampus at 7 T--in vivo MRI.
The human hippocampus plays a central role in various neuropsychiatric disorders, such as temporal lobe epilepsy (TLE), Alzheimer's dementia, mild cognitive impairment, and schizophrenia. Its volume, morphology, inner structure, and function are of scientific and clinical interest. Magnetic resonance (MR) imaging is a ...
18,727,048
Simultaneous flow cytometric detection of basophil activation marker CD63 and intracellular phosphorylated p38 mitogen-activated protein kinase in birch pollen allergy.
Phosphorylation of p38 MAPK is a crucial step in IgE-receptor signaling in basophils. The relation of p38 MAPK to the well-validated diagnostic cell surface marker CD63 has not been evaluated in a clinical allergy model. Expression of CD63 and phosphorylation of p38 MAPK were analyzed flow cytometrically in anti-IgE-ga...
18,727,065
In-stent restenosis in bare metal stents versus sirolimus-eluting stents after primary coronary intervention for acute myocardial infarction and subsequent transcoronary transplantation of autologous stem cells.
Following stenting for acute myocardial infarction, transcoronary transplantation of granulocyte-colony stimulating factor (G-CSF) mobilized autologous stem cells (ASC) has been shown to result in an increased in-stent restenosis rate of bare metal stents (BMS). This study sought to compare the extent of neointimal gro...
18,727,076
Balanced left ventricular myocardial SSFP-tagging at 1.5T and 3T.
The purpose of the study was to evaluate the performance of steady-state free precession (SSFP)-tagging at 1.5T and 3T and to define the ideal settings with respect to optimized tag contrast throughout the cardiac cycle for both field strengths. To identify optimal imaging parameters data acquisition was repeated for d...
18,727,081
In vivo 1H NMR measurement of glycine in rat brain at 9.4 T at short echo time.
Glycine is an amino acid present in mammalian brain, where it acts as an inhibitory and excitatory neurotransmitter. The two detectable protons of glycine give rise to a singlet at 3.55 ppm that overlaps with the more intense myo-inositol resonances, and its measurement has traditionally required specific editing effor...
18,727,088
Image-based coronary tracking and beat-to-beat motion compensation: feasibility for improving coronary MR angiography.
A method to reduce the effect of motion variability in MRI of the coronary arteries is proposed. It involves acquiring real-time low-resolution images in specific orthogonal orientations, extracting coronary motion from these images, and then using this motion information to guide high-resolution MR image acquisition o...
18,727,098
Modeling SSFP functional MRI contrast in the brain.
Steady-state free precession (SSFP) has recently been proposed for function MRI because of the potential for reducing image distortion and signal dropout. Several different contrast mechanisms have been suggested to explain the reported observations, but there has been limited work comparing theory with experiment in t...
18,727,099
One year perspective on COURAGE.
Doctor: "Ma'am you need an angioplasty". "Doctor, the newspaper says that medicine is as good as angioplasty". Doctor: "Ma'am you're having a heart attack". The COURAGE trial was published 1 year ago and received attention from the media, patients, and other medical specialties concerning the value of percutaneous coro...
18,727,125
Robotic-assisted radical cystectomy.
To evaluate the emerging role of robotic-assisted radical cystectomy (RARC) in the management of bladder cancer. Review of the published literature on robotic-assisted radical cystectomy, including data from our cystectomy series of 30 patients. Nearly 150 procedures have been performed worldwide. The benefits of robot...
18,727,138
Ion mobility adds an additional dimension to mass spectrometric analysis of solution-phase hydrogen/deuterium exchange.
The goal of this study was to determine the utility of adding ion mobility spectrometry to studies probing the solution-phase hydrogen/deuterium exchange (HX) of proteins. The HX profile of the Hck SH3 domain was measured at both the intact protein and the peptic peptide levels in the Waters Synapt HDMS system which us...
18,727,141
Effect of age and food intake on dietary carbon turnover recorded in sheep wool.
We present the results of a series of controlled feeding experiments with sheep, designed to investigate the effects of age and level of food intake on the kinetics of incorporation of the dietary carbon signal into wool. Four different groups of three sheep each, ranging in age from 6 to 78 months, were fed a C(3) die...
18,727,150
The gap-filling sequence on the left arm of chromosome 2 in fission yeast Schizosaccharomyces pombe.
We report a gap-filling sequence between SPBPB21E7.09 (in contig c1348) and SPBPB10D8.01 (in contig pB10D8) on the left arm of chromosome 2 in the fission yeast, Schizosaccharomyces pombe. The sequence was determined from a BAC clone overlapping SPBPB21E7.01c (eno102) (in contig c1348) and SPBC1683.07 (mal1) (in contig...
18,727,152
U.S.: PEPFAR reauthorization bills pass House, Senate committee.
On 2 April 2008, the U.S. House of Representatives passed a bill (H.R. 5501) to reauthorize the President's Emergency Plan for AIDS Relief (PEPFAR). The House bill would authorize the appropriation of US$50 billion over the next five years--40 percent more than the US$30 billion requested by President George W. Bush.
18,727,191
Refugee claimant's identity as cross-dresser must be considered in assessing adequacy of state protection.
On 11 December 2007, the Federal Court allowed Jose Hernandez's application for judicial review of a November 2006 decision by the Refugee Protection Division of the Immigration and Refugee Board, which found that the applicant was neither a Convention refugee nor a person in need of protection. Hernandez had requested...
18,727,196
Natural history of hepatocellular carcinoma.
Hepatocellular carcinoma (HCC) is a slowly growing tumor, whose natural history is not completely known. Since the hepatocarcinogenetic process may evolve for years in a stepwise fashion from premalignant to overt HCC, detection of early, better treatable tumors is made possible by surveillance of patients at risk. A 6...
18,727,270
Brunner's gland hamartoma: a case report and review of literature.
Brunner's hamartoma is a quite rare neoformation whose origin is not completely clear. A case of a 69-year-old man with recurrent epigastric pain and an endoscopic finding of a duodenal mass is reported. The complete removal of hamartoma can give a complete remission of symptoms. Hamartoma can be only diagnosed by endo...
18,727,278
[Taxonomic diversity of parasites in agnathans and fishes from the Volga River basin. VI. Acanthocephala, Hirudinea and Bivalvia].
The checklist of Acanthocephala, Hirudinea, and Bivalvia parasitizing agnathans and fishes in the Volga River basin is presented. Hosts and areas of distribution are indicated for each parasites species. The checklist includes 10 species of acanthocephalans, 7 species of leeches, and 9 species of Bivalvia (at the gloch...
18,727,362
[Morphology of the blackfly species group macropyga of the genus Prosimulium roubaud, 1906, and re-establishment of the generic name Taeniopterna Enderlein, 1925 for this group (Diptera: Simuliidae)].
The genus Taeniopterna with the types species Melusina macropyga Lundstrom, 1911 was proposed by Enderlein in 1925. Later this taxon was considered as the species group macropyga in the genus Prosimulium Roubaud, 1906 by many authors (Rubzov, 1956; Crosskey et Howard, 1997; Adler et al., 2004, and others). However, dif...
18,727,367
[Eimeria of cattle in the Republic of Dagestan].
Data on Eimeria (Sporozoa: Coccidia) parasitizing cattle in different regions of the Republic of Dagestan are given. Eight species of the genus were found. Eimeria zuernii, E. subspherica, and E. bovis appeared to be the dominate species. Total infestation rate in the republic is 67.7%, while in mountain regions of Dag...
18,727,369
[The geographic varyability of the polytene chromosome banding sequence of non-biting midje Chironomus pseudothummi str. (Diptera, Chironomidae)].
The karyotypes and chromosomal polymorphism of Chironomus pseudothummi were investigated in different parts of its range. It was established that chromosomal variability in the natural populations of this species was represented mainly by the inversion polymorphism of arm G. Only rare and unique inversions were found a...
18,727,406
[Diencephalo-telencephalic changes of tyrosine hydroxylase in rats and common frogs (Rana temporaria) after sleep deprivation].
Based on sleep deprivation-produced changes of electrographic parameters of the wakefulness--sleep cycle (WSC) in rats and common frogs, dynamics of activity of tyrosine hydroxylase, the key enzyme of dopamine synthesis, was studied immunohistochemically in substantia nigra and nigrostriatal pathway in rats and in stri...
18,727,412
[Distribution of metabolic activity (cytochrome oxidase) and immunoreactivity to calcium-binding proteins in turtle brainstem auditory nuclei].
Using histochemical and immunohistochemical techniques, distribution of activity of oxidative mitochondrial enzyme cytochrome oxidase (CO) and of immunoreactivity to calcium-binding proteins has been studied in spiral ganglion and auditory nuclei of brainstem in two turtle species. It has been shown that immunoreactivi...
18,727,419
[Hypersiderosis and dissiderosis in the context of data on hemochromatosis microelementosis].
The review summarizes the results of the state-of-the-art studies of hemochromatosis (HC): iron-regulatory genes (HFE, HJV, HAMP, TFR2, SLC40A1) have been discovered; the HC types caused by mutations in these genes (types 1, 2, 3, and 4 in the OMIM register) have been identified; the inflammation anemia (IA) mediator -...
18,727,423
[Effect of apoptosis proteins on function of vasopressin- and dopaminergic hypothalamic neurons].
To study character of effect of apoptosis signal proteins on activities of neurosecretory cells and neurons of rat hypothalamus, pharmacologic inhibitors of proapoptotic protein p53 Pifithrin-alpha and antiapoptotic protein Bcl-2 HA14-1 were injected into the hypothalamus. Activation of vasopressinergic neurosecretory ...
18,727,420
[The morphofunctional characteristics of proteins of nucleolar organizers in uterine smooth muscle tumors].
The authors have shown the activity of argyrophylic nucleolar organizer region proteins (Ag-NOR-proteins) in the uterine leiomyomas of varying histological structure and determined their relationship to the growth rate, size, and site of a node and endometrial pathology. The investigation indicat yomas with significant...
18,727,427
[Melatonin expression in nasal polyps in patients with asthmatic triad].
The expression of melatonin in nasal polyps versus the histological structure of tissue was studied in 11 patients with aspirin-induced asthma (AIA), 8 patients with asthma without aspirin intolerance, 13 patients with polypous rhinosinusopathy (PR) without bronchopulmonary diseases, and 10 apparently healthy individua...
18,727,430
Antiviral Chemistry & Chemotherapy's current antiviral agents FactFile (2nd edition): DNA viruses.
Although most of the recent attempts to develop new antiviral agents have been focussed on RNA viruses (in particular, HIV and hepatitis C virus), a few new compounds are now awaiting their entry into the field of DNA viruses, particularly poxviruses, such as variola virus, because of the bioterrorist context, and herp...
18,727,440
[Congenital neuroblastoma].
The paper describes a clinicoanatomic case of congenital neuroblastoma of various differentiation degree in a boy aged 1 year and 9 months after 4 courses of up-to-date multidrug therapy.
18,727,436
Clinical features of legume allergy in children from a Mediterranean area.
Lentils, chickpeas, beans, and peas are the most common consumed legumes in the Mediterranean area. However, there is little information about allergy to these legumes. To describe the clinical features of a Spanish pediatric population allergic to legumes (lentils, chickpeas, peas, white beans, and peanuts), to evalua...
18,727,474
The subthalamic nucleus. Part I: development, cytology, topography and connections.
This monograph (Part I of two volumes) on the subthalamic nucleus (STN) accentuates the gap between experimental animal and human information concerning subthalamic development, cytology, topography and connections. The light and electron microscopical cytology focuses on the open nucleus concept and the neuronal types...
18,727,483
Fevers, genes, and innate immunity.
The characterization of patients with recurrent inflammatory syndromes into distinct clinical phenotypes provided early clues to the mode of inheritance of these conditions and facilitated the subsequent identification of causative gene mutations. The prototype autoinflammatory syndrome, familial Mediterranean fever, i...
18,727,492
[Effect of lipopolysaccharide on cyclooxygenase-2 expression and prostaglandin E2 release in human nasal epithelia].
To detect cyclooxygenase-2 (COX-2) expression and prostaglandin E2 (PGE2) release in human nasal epithelia (HNE) induced by lipopolysaccharide (LPS) in different concentration gradient and time gradient, and to investigate their roles in nasal inflammatory pathogenesis. Western Blot and fluorescent real time quantitati...
18,727,513
Determination of coenzyme Q10 content in raw materials and dietary supplements by high-performance liquid chromatography-UV: collaborative study.
An international collaborative study was conducted of a high-performance liquid chromatographic (HPLC)-UV method for the determination of coenzyme Q10 (CoQ10, ubidecarenone) in raw materials and dietary supplements. Ten collaborating laboratories determined the total CoQ10 content in 8 blind duplicate samples. Sample m...
18,727,527
Simultaneous estimation of acetylsalicylic acid and clopidogrel bisulfate in pure powder and tablet formulations by high-performance column liquid chromatography and high-performance thin-layer chromatography.
This paper describes validated high-performance column liquid chromatographic (HPLC) and high-performance thin-layer chromatographic (HPTLC) methods for simultaneous estimation of acetylsalicylic acid (ASA) and clopidogrel bisulfate (CLP) in pure powder and formulations. The HPLC separation was achieved on a Nucleosil ...
18,727,533
Fatty acid profile of Canadian dairy products with special attention to the trans-octadecenoic acid and conjugated linoleic acid isomers.
Current scientific evidence indicates that consumption of industrial trans fatty acids (TFA) produced via partial hydrogenation of vegetable oils increases the risk of coronary heart disease. However, some studies have suggested that ruminant TFA, especially vaccenic acid (VA or 11t-18:1) and rumenic acid (RA or 9c,11t...
18,727,541
Comparison of digestibility and quality of intact proteins with their respective hydrolysates.
Quality of proteins depends on their composition in essential amino acids and on the availability of amino acids. Great interest has been shown in the role played by hydrolysates of proteins in clinical diets for pathologies with reduced absorptive capacity and food allergies caused by intact protein epitopes. Milk pro...
18,727,562
Practice of venom immunotherapy in the United Kingdom: a national audit and review of literature.
Venom immunotherapy (VIT) is the only effective treatment for prevention of serious allergic reactions to bee and wasp stings in sensitized individuals. However, controversies exist relating to diagnosis, indications for treatment and treatment schedules. We audited current practice of VIT in the United Kingdom to eval...
18,727,621
Medication overuse headache: predictors and rates of relapse in migraine patients with low medical needs. A 1-year prospective study.
The aim of this study was to evaluate the rates and predictors of relapse, after successful drug withdrawal, in migraine patients with medication overuse headache (MOH) and low medical needs. The study population, study design, inclusion criteria and short-term effectiveness of the medication withdrawal strategies have...
18,727,648
Evaluation of a capillary blood collection system for screening for hemoglobinopathies in remote areas.
Accurate estimation of hemoglobin (Hbs) A, Hb A(2), Hb F and abnormal Hb is required for diagnosis of hemoglobinopathies and genetic counseling. High pressure liquid chromatography (HPLC) is the most suitable approach available. But for 70% of the rural Indian population, HPLC analysis facilities are not available and ...
18,727,652
Association of cortisol and dehydroepiandrosterone sulphate levels in serum with periodontal status in older Japanese adults.
The associations between periodontitis and stress-related steroid hormone levels released by the hypothalamic-pituitary-adrenal axis are poorly understood. In this study, we examined the association between levels of the stress-related steroid hormones cortisol and dehydroepiandrosterone-sulphate (DHEAS) and periodonti...
18,727,654
Raised chondroitin sulphate WF6 epitope levels in gingival crevicular fluid in chronic periodontitis.
To determine the levels of chondroitin sulphate (CS) WF6 epitope, recognized by WF6 monoclonal antibody, in gingival crevicular fluid (GCF) from different stages of periodontal disease and healthy periodontium, and to correlate those levels with clinical parameters. GCF samples, collected from 389 sites, were analysed ...
18,727,658
Hydroxychloroquine-induced hyperpigmentation: the staining pattern.
We report two cases of hydroxychloroquine-induced hyperpigmentation presenting in a 50-year-old Caucasian female (case 1) and a 78-year-old female (case 2), both receiving 400 mg per day. Case 1 had an arthritis predominant undifferentiated connective tissue disease, which was treated with hydroxychloroquine for 4-5 ye...
18,727,667
Automated MRI analysis for identification of hippocampal atrophy in temporal lobe epilepsy.
Hippocampal sclerosis is frequently associated with hippocampal atrophy (HA), which is often observed on routine magnetic resonance imaging (MRI) of patients with medial temporal lobe epilepsy (MTLE). Manual morphometry of the hippocampus is sensitive to detecting HA, but is time-consuming and prone to operator error. ...
18,727,679
Differing lung function development in infants with univentricular hearts compared with healthy infants.
To compare the difference in lung function development of healthy controls and patients with univentricular hearts from birth prior to surgery and during the first year of life when cardiac shunt procedures and the cavopulmonary connection are required. Tidal flow-volume measurements and single-occlusion tests were per...
18,727,686
Anaemia and marrow fibrosis in patients with primary hyperparathyroidism before and after curative parathyroidectomy.
To determine the relationship between anaemia and myelofibrosis in patients with symptomatic primary hyperparathyroidism (PHPT) and to assess the effect of curative parathyroidectomy on anaemia and marrow fibrosis. In this prospective follow-up study of 28 consecutive patients with symptomatic PHPT from January 2005 to...
18,727,711
Experiencing cancer treatment decision-making in managed care.
This paper is a report of a study to explore women's perceptions of and experiences with breast cancer treatment decision-making in managed care organizations (MCOs). Managed care organizations are the predominant form of employer-sponsored healthcare insurance in the United States of America. These healthcare financin...
18,727,748
Presence of patients' families during cardiopulmonary resuscitation: physicians' and nurses' opinions.
This paper is a report of a study to determine the opinions of physicians and nurses who work in a university hospital intensive care unit and emergency department about the presence of patients' families during cardiopulmonary resuscitation in these units. Healthcare professionals have conflicting opinions about the p...
18,727,768
Induced perceptual grouping.
The term perceptual grouping is associated with classical principles such as similarity and proximity. This article reports induced perceptual grouping, a phenomenon that occurs when placement of a uniform set of items near a structured set induces grouping within the otherwise uniform set. For example, when items grou...
18,727,785
Activity of moxifloxacin against the urogenital mycoplasmas Ureaplasma spp., Mycoplasma hominis and Mycoplasma genitalium and Chlamydia trachomatis.
The activity of moxifloxacin was compared with that of other antimicrobial agents against 54 strains of Ureaplasma spp., 54 strains of Mycoplasma hominis, 14 strains of Mycoplasma genitalium, and 44 strains of Chlamydia trachomatis. Moxifloxacin inhibited 90% of all isolates at a concentration </=1 mg/L, being the m...
18,727,805
Double dermal sinuses: a case study.
Dermal sinus tracts are rare congenital lesions located in the midline characterized by a cutaneous pit or dimple. They occur all along the midline neuroaxis, from the nasion and occipital area down to the lumbar and sacral regions, most frequently in the lumbar and lumbosacral region. Here we report a 5-year-old girl ...
18,727,820
Ultra-brief intervention for problem drinkers: research protocol.
Helping the large number of problem drinkers who will never seek treatment is a challenging issue. Public health initiatives employing educational materials or mass media campaigns have met with mixed success. However, clinical research has developed effective brief interventions to help problem drinkers. This project ...
18,727,823
Effect of the ethinylestradiol/norelgestromin contraceptive patch on body composition. Results of bioelectrical impedance analysis in a population of Italian women.
As weight gain is one of the most frequently cited reasons for not using and for discontinuing hormonal contraceptives, in an open-label, single-arm, multicentre clinical study we evaluated the effect of the ethinylestradiol/norelgestromin contraceptive patch (EVRA, Janssen-Cilag International, Belgium) on body composi...
18,727,825
Costs of treating patients with schizophrenia who have illness-related crisis events.
Relatively little is known about the relationship between psychosocial crises and treatment costs for persons with schizophrenia. This naturalistic prospective study assessed the association of recent crises with mental health treatment costs among persons receiving treatment for schizophrenia. Data were drawn from a l...
18,727,831
Risk factors for falls with severe fracture in elderly people living in a middle-income country: a case control study.
Fracture after falling has been identified as an important problem in public health. Most studies of risk factors for fractures due to falls have been carried out in developed countries, although the size of the elderly population is increasing fast in middle income countries. The objective of this paper is to identify...
18,727,832
Fetal ascites owing to congenital cytomegalovirus: response to ganciclovir.
A term newborn with severe congenital cytomegalovirus (CMV) infection is described. Fetal ascites was detected at 28 weeks gestation, and at birth there was tense ascites. There was intra-uterine growth retardation, microcephaly, chorioretinitis, jaundice, purpura and pneumonitis. Computed tomographic scan of the brain...
18,727,854
Poly(hydroxyethyl methacrylate)-based co-polymeric hydrogels for transdermal delivery of salbutamol sulphate.
Various co-polymeric hydrogels for transdermal delivery of salbutamol sulphate were synthesized using 2-hydroxyethyl methacrylate (HEMA), methacrylic acid (MAA) and N-[3-(dimethylamino)propyl]methacrylamide (DMAPMA) in the presence of ammonium persulphate (APS) and N,N,N',N'-tetramethylethylenediamine (TEMED) as redox ...
18,727,860
[Assessment of patient satisfaction and preferences with inhalers in asthma with the FSI-10 Questionnaire].
Lack of adherence to inhaled corticosteroid therapy is common in patients with asthma, and it has been suggested that allowing patients to choose their own inhalers would resolve this problem. The FSI-10 (Feeling of Satisfaction with Inhaler) is a self-completed questionnaire to assess patient opinions regarding ease o...
18,727,886
Developmental timing: let-7 function conserved through evolution.
Expression of the heterochronic microRNA let-7 is tightly correlated with the onset of adult development in many animals, suggesting that it functions as an evolutionarily conserved developmental timer. This hypothesis has now been confirmed by studies in Drosophila.
18,727,906
HIV-1 infection: going nuclear with TNPO3/Transportin-SR2 and integrase.
Factors necessary for HIV-1 nuclear import have been sought for many years. Recent reports suggest that TNPO3/Transportin-SR2 binds to HIV-1 integrase and is required for HIV-1 infection of interphase cells.
18,727,908
Vision: attention makes the cup flow over.
Scalp potentials are surprisingly informative about visual attention: a recent study that used them to record neural responses to up to four superimposed visual patterns simultaneously has now revealed the flow of attentional signals back to visual cortex.
18,727,909
Pleiotrophin prevents cocaine-induced toxicity in vitro.
Pleiotrophin is a cytokine involved in differentiation, survival and repair processes in the central nervous system. Pleiotrophin is upregulated in the brain after administration of different drugs of abuse, thus suggesting a protective role of this cytokine on drug-induced toxicity. We have tested this hypothesis in v...
18,727,926