title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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A restoratively driven ridge categorization, as determined by incorporating ideal restorative positions on radiographic templates utilizing computed tomography scan analysis. | The introduction of implants into the field of dentistry has revolutionized the way we evaluate edentulous ridges. In an attempt to evaluate the deficient edentulous ridge, numerous classification systems have been proposed. Each of these classification systems implements a different approach for evaluating and plannin... | 18,783,410 |
Alveolar ridge regeneration with equine spongy bone: a clinical, histological, and immunohistochemical case series. | In the case of localized ridge atrophy, a ridge augmentation procedure, with the use of bone substitutes and barrier membranes, may then be necessary. The aim of the present study was a clinical, histological, and immunohistochemical evaluation of an equine spongy bone in alveolar ridge augmentation procedures. Five pa... | 18,783,426 |
Cerebral MRI abnormalities associated with vigabatrin therapy. | Investigate whether patients on vigabatrin demonstrated new-onset and reversible T(2)-weighted magnetic resonance imaging (MRI) abnormalities. MRI of patients treated during vigabatrin therapy was reviewed, following detection of new basal ganglia, thalamus, and corpus callosum hyperintensities in an infant treated for... | 18,783,433 |
Diversity of Sinorhizobium strains nodulating Medicago sativa from different Iranian regions. | Alfalfa is believed to have originated in north-western Iran and has a long history of coexistence with its bacterial symbiont Sinorhizobium in soils of Iran. However, little is known about the diversity of Sinorhizobium strains nodulating Iranian alfalfa genotypes. In this study, Sinorhizobium populations were sampled... | 18,783,438 |
Haemophilia A: patients' knowledge level of treatment and sources of treatment-related information. | There are minimal or no data regarding the extent of patient and/or parent/legal guardian/caregiver knowledge about haemophilia A and its treatment, their sources for this information, or their preferred methods of communication. A pilot study using a survey instrument developed by haemophilia nurse coordinators was co... | 18,783,441 |
Unilateral or "side-locked" migrainous headache with autonomic symptoms linked to night guard use. | Night guards are commonly prescribed as a palliative measure for bruxism, temporomandibular joint symptoms, and associated disorders. We describe a patient with a 10- to 12-year history of night guard use with concurrent unilateral side-locked migrainous headaches with autonomic symptoms characteristic of trigeminal au... | 18,783,445 |
Serum concentrations of s100b and NSE in migraine. | The protein s100b indicates astrocytal damage as well as dysfunction of the blood-brain barrier (BBB), and neuron-specific enolase (NSE) is regarded as a marker for neuronal cell loss. Recently, s100b was shown to be a potentially useful marker for migraine in children. In this study, we investigated the levels of s100... | 18,783,450 |
Persistence of HMO performance measures. | To simplify the decision-making process, we propose and implement an approach to assess the stability of health plan performance over time when multiple indicators of performance exist. National Committee for Quality Assurance Health Care Effectiveness Data and Information Set data for childhood immunization for both p... | 18,783,460 |
Low PAI-1 activity in relation to inflammatory parameters, insulin profile and body mass index. | High plasminogen activator inhibitor type 1 (PAI-1) activity is associated with inflammatory reactions and insulin resistance, but it is unclear what regulates PAI-1 activity at the low end. The purpose of this study was to investigate if patients with low PAI-1 activity have a lack of inflammatory response or a low in... | 18,783,478 |
Pathogenesis of Helicobacter pylori infection. | The clinical outcome of Helicobacter pylori infection is determined by a complex scenario of interactions between the bacterium and the host. The main bacterial factors associated with colonization and pathogenicity comprise outer membrane proteins including BabA, SabA, OipA, AlpA/B, as well as the virulence factors Ca... | 18,783,516 |
The advantages of topical combination therapy in the treatment of inflammatory dermatomycoses. | Dermatomycoses are contagious superficial fungal infections, which are highly prevalent in developed and developing countries. Caused by a range of Epidermophyton, Microsporum and Trichophyton species, dermatomycoses manifest on glabrous skin as 'ringworm', an annular scaly lesion with a variable inflammatory component... | 18,783,560 |
Association between H-RAS T81C genetic polymorphism and gastrointestinal cancer risk: a population based case-control study in China. | Gastrointestinal cancer, such as gastric, colon and rectal cancer, is a major medical and economic burden worldwide. However, the exact mechanism of gastrointestinal cancer development still remains unclear. RAS genes have been elucidated as major participants in the development and progression of a series of human tum... | 18,783,589 |
LOMA: a fast method to generate efficient tagged-random primers despite amplification bias of random PCR on pathogens. | Pathogen detection using DNA microarrays has the potential to become a fast and comprehensive diagnostics tool. However, since pathogen detection chips currently utilize random primers rather than specific primers for the RT-PCR step, bias inherent in random PCR amplification becomes a serious problem that causes large... | 18,783,594 |
Validity of a self-reported measure of familial history of obesity. | Familial history information could be useful in clinical practice. However, little is known about the accuracy of self-reported familial history, particularly self-reported familial history of obesity (FHO). Two cross-sectional studies were conducted. The aims of study 1 was to compare self-reported and objectively mea... | 18,783,616 |
Acknowledging and adapting to dietetic students' changing needs. | Various societal influences have shaped the way dietetic students view and react to current educational situations. Students' perspectives were sought on conditions that caused stress in the educational environment, what they thought educators did not understand about them, and changes their faculty or preceptors had m... | 18,783,637 |
[Biostatistics: a fundamental tool for the elaboration of radiological articles]. | Biostatistics has become an indispensable tool in all domains of the Health Sciences. Biostatistics is essential for ensuring valid decision making, and knowing the basic principles of biostatistics well will enable us to use this tool correctly. In this article, first biostatistics is defined and then its use and just... | 18,783,646 |
[Femoroacetabular impingement: radiographic diagnosis--what the radiologist should know]. | The purpose of this article is to show the important radiographic criteria that indicate the two types of femoroacetabular impingement: pincer and cam impingement. In addition, potential pitfalls in pelvic imaging concerning femoroacetabular impingement are shown. Femoroacetabular impingement is a major cause for early... | 18,783,647 |
[Useful tips for CT-angiography]. | Multidetector CT scanners are now available in most hospitals; this technology makes it possible to perform cardiac studies. The technique depends on the technology, and certain points must be taken into consideration to improve the results of cardiac studies. We discuss four key points for ensuring high-quality multid... | 18,783,648 |
[The pharmacokinetics of metronidazole and gentamicin in a single preoperative dose as antibiotic prophylaxis in colorectal surgery]. | To describe, in patients undergoing colorectal surgery (CRS), the pharmacokinetics of a single, prophylactic preoperative dose of 1,500 mg of metronidazole plus 240 mg gentamicin and measure its efficacy in accordance with the accepted pharmacodynamic and microbiological parameters. Thirty-six patients undergoing CRS a... | 18,783,706 |
Regulated association of caveolins to lipid droplets during differentiation of 3T3-L1 adipocytes. | Caveolins, structural protein coats of caveolae primarily involved in membrane-related functions, have also been found associated to lipid droplets (LD), specialized organelles for fat storage. In the present study, we wanted to delineate the main features that govern the presence of caveolin-1 on adipocyte lipid dropl... | 18,783,721 |
Meprins, membrane-bound and secreted astacin metalloproteinases. | The astacins are a subfamily of the metzincin superfamily of metalloproteinases. The first to be characterized was the crayfish enzyme astacin. To date more than 200 members of this family have been identified in species ranging from bacteria to humans. Astacins are involved in developmental morphogenesis, matrix assem... | 18,783,725 |
Evidence Locator: sources of evidence-based dentistry information. | Multiple resources are available to help practitioners access the latest scientific evidence. Evidence-based dentistry (EBD) is an approach to clinical decision making that incorporates the most current and comprehensive scientific evidence with the practitioner's judgment and the patient's needs and preferences. One c... | 18,783,754 |
Psychometric properties and cross-cultural equivalence of the Arabic Social Capital Scale: instrument development study. | Social capital, defined as an investment in relationships that facilitates the exchange of resources, has been identified as a possible protective factor for child health in the context of risk factors such as poverty. Reliable and valid measures of social capital are needed for research and practice, particularly in n... | 18,783,773 |
Ultrafine porous carbon fibers for SO2 adsorption via electrospinning of polyacrylonitrile solution. | This work describes the potential capability of ultrafine porous carbon fibers (UPCF) prepared via electrospinning in the removal of SO2 from a mixture gas stream. A series of conventional PCF (CPCF) and ultrafine PCF (UPCF) were produced under the identical conditions and UPCF was also modified. Compared to the CPCF, ... | 18,783,785 |
Prospective study of etiologic agents of acute gastroenteritis outbreaks in child care centers. | To investigate the etiology of outbreaks of acute gastroenteritis (AGE) in children attending childcare centers (CCCs) in North Carolina between October 2005 and March 2007. In this prospective study of outbreaks of AGE in CCCs, stool specimens from symptomatic children and environmental surface swabs were tested for a... | 18,783,794 |
The relationship of retinol binding protein 4 to changes in insulin resistance and cardiometabolic risk in overweight black adolescents. | To assess, among overweight non-hispanic black adolescents the relationship of changes in plasma retinol binding protein 4 (RBP4) over 3 years to changes in insulin resistance (IR) and 4 associated cardiometabolic risks. Nested, retrospective study of 51 overweight, post-pubertal non-Hispanic black participants in the ... | 18,783,798 |
Links between parenting and extra-familial relationships: nature or nurture? | The current paper examined associations between parenting and both peer group characteristics and friendship quality within a genetically sensitive design. Participants were aged 12-19 years (approximately equal numbers of males and females), including 424 sibling pairs and 1185 twin pairs, of whom 328 were MZ, 311 wer... | 18,783,821 |
PP2 regulates human trophoblast cells differentiation by activating p38 and ERK1/2 and inhibiting FAK activation. | Throughout gestation, fetal growth and development depend, in part, on placental transfer of nutrients from the maternal circulation. This latter function depends on multinucleated, terminally differentiated syncytiotrophoblasts. In vitro, freshly isolated cytotrophoblast cells differentiate spontaneously into syncytio... | 18,783,823 |
Simulating calcium influx and free calcium concentrations in yeast. | Yeast can proliferate in environments containing very high Ca(2+) primarily due to the activity of vacuolar Ca(2+) transporters Pmc1 and Vcx1. Yeast mutants lacking these transporters fail to grow in high Ca(2+) environments, but growth can be restored by small increases in environmental Mg(2+). Low extracellular Mg(2+... | 18,783,827 |
Metal levels in the bones and livers of globally threatened marbled teal and white-headed duck from El Hondo, Spain. | El Hondo is a key area for marbled teal and white-headed duck. We present Pb, Cu, Zn, Se, and As data for bone and liver in birds found dead between 1996 and 2001. Several metals were higher in adult white-headed ducks than in marbled teal. They were higher in female than in male white-headed ducks, and did not differ ... | 18,783,829 |
Increased plasma levels of 8-iso-PGF2alpha and IL-6 in an elderly population with depression. | Oxidative damage and immune-inflammatory activation have been suggested to play a role in depression. The purpose of the study was to investigate possible associations and interactions of these pathophysiological mechanisms in geriatric depression by determining the levels of plasma 8-iso-prostaglandin F(2alpha) (8-iso... | 18,783,834 |
Priority setting for technology adoption at a hospital level: relevant issues from the literature. | The increasing pace of development of healthcare technologies obliges hospitals to increase both the rationality and the accountability of priority setting for technology adoption. This paper aims at identifying which are the relevant issues for technology assessment and selection at a hospital level and at grouping th... | 18,783,844 |
Conflict in schools: student nurses' conflict management styles. | Unless conflicts between the students and the instructors can be successfully managed, they will certainly result in negative outcomes for the students. The conflict management styles of the students should be recognized in detail in order to attain positive outcomes in regard to the conflict management styles. The pur... | 18,783,853 |
Examination of the association between male gender and preterm delivery. | To examine possible reasons why a male fetus constitutes a risk factor for preterm delivery. Retrospective study of deliveries from hospital database in a UK teaching hospital. The population comprised all deliveries >23 weeks over an 11-year period, excluding multiples, terminations and pregnancies with major abnor... | 18,783,867 |
The relationship between erectile dysfunction and lower urinary tract symptoms and the role of phosphodiesterase type 5 inhibitors. | The relationship between lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) and the potential interplay of phosphodiesterase type 5 inhibitors (PDE5-I) have clinical implications for both patient screening and treatment. To describe the current literature assessing the LUTS-ED relationship and the role o... | 18,783,872 |
Time, symptom burden, androgen deprivation, and self-assessed quality of life after radical prostatectomy or watchful waiting: the Randomized Scandinavian Prostate Cancer Group Study Number 4 (SPCG-4) clinical trial. | Quality-of-life outcomes are important in the choice of treatment strategy for men with localized prostate cancer. To evaluate how follow-up time, number of physical symptoms, and presence of androgen deprivation affected quality of life among men randomized to radical prostatectomy or watchful waiting. The study group... | 18,783,877 |
Test of memory malingering and word memory test: a new comparison of failure concordance rates. | Two commonly used symptom validity tests are the Test of Memory Malingering (TOMM) and Word Memory Test (WMT). After examining TOMM-WMT failure concordance rates, Green [Green, P. (2007). Making comparisons between forced-choice effort tests. In K. B. Boone (Ed.), Assessment of feigned cognitive impairment (pp. 50-77).... | 18,783,912 |
Adhesive efficiency of spider prey capture threads. | Cribellar capture threads are comprised of thousands of fine silk fibrils that are produced by the spigots of a spider's cribellum spinning plate and are supported by larger interior axial fibers. This study examined factors that constrain the stickiness of cribellar threads spun by members of the orb-weaving family Ul... | 18,783,928 |
Isolation of the orthologue of the cerato-ulmin gene in Ophiostoma quercus and characterization of the purified protein. | Ophiostoma quercus is an ophiostomatoid fungus strictly related to the Ophiostoma's (O. ulmi, O. novo-ulmi, and O. himal-ulmi) that cause Dutch elm disease (DED). O. quercus has a number of morphological characteristics in common with the DED pathogens, and is a well-known and economically important sapstaining fungus ... | 18,783,930 |
Hormone replacement therapy and the risk of breast cancer. | Hormone replacement therapy (HRT) has had a chequered history ever since its initial use to manage menopausal symptoms. It is clear that it has many other effects and here we review its impact on the risk of breast cancer. A clear risk is seen for current uses of combined oestrogen/progestagen pills, but this returns t... | 18,783,940 |
Structure-activity relationships of compounds targeting mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate synthase. | We report on a target-based approach to identify possible Mycobacterium tuberculosis DXS inhibitors from the structure of a known transketolase inhibitor. A small focused library of analogs was assembled in order to begin elucidating some meaningful structure-activity relationships of 3-(4-chloro-phenyl)-5-benzyl-4H-py... | 18,783,951 |
Trapping of intact, singly-charged, bovine serum albumin ions injected from the atmosphere with a 10-cm diameter, frequency-adjusted linear quadrupole ion trap. | High-resolution real-time particle mass measurements have not been achievable because the enormous amount of kinetic energy imparted to the particles upon expansion into vacuum competes with and overwhelms the forces applied to the charged particles within the mass spectrometer. It is possible to reduce the kinetic ene... | 18,783,963 |
Synthesis, characterization and antioxidant activity copper-quercetin complex. | Quercetin (3,3',4',5,7-pentahydroxyflavone) one of the most abundant dietary flavonoids, has been investigated in the presence of Cu(II) in methanol. The spectroscopic studies (UV-vis, (1)H NMR and IR) were useful to assess the relevant interaction of Quercetin with Cu(II) ions, the chelation sites and dependence of th... | 18,783,981 |
The childhood obesity pandemic: Promoting knowledge for undergraduate nursing students. | The rise in childhood obesity is acknowledged as a major health problem in many countries. Health issues directly related to the childhood obesity pandemic are numerous as are the risk factors in its development. No single strategy is likely to be effective in reversing this alarming trend, rather, nurses need to work ... | 18,783,989 |
Use of p16-INK4A overexpression to increase the specificity of human papillomavirus testing: a nested substudy of the NTCC randomised controlled trial. | Human-papillomavirus (HPV) testing is more sensitive, but less specific, than conventional cytology for detecting high-grade cervical intraepithelial neoplasia (CIN). We assessed whether HPV testing with triage by p16-INK4A overexpression can increase specificity while maintaining sensitivity. HPV-positive women were e... | 18,783,988 |
Accelerating risk of Fidelis lead fracture. | Sprint Fidelis (Medtronic Inc., Minneapolis, Minnesota) is a 6.6-F implantable cardioverter-defibrillator lead. In October 2007 the manufacturer suspended distribution of Sprint Fidelis leads secondary to high early fracture rates. Reprogramming of lead impedance alerts was recommended to try to reduce inappropriate sh... | 18,783,996 |
Practical Poissonian-Gaussian noise modeling and fitting for single-image raw-data. | We present a simple and usable noise model for the raw-data of digital imaging sensors. This signal-dependent noise model, which gives the pointwise standard-deviation of the noise as a function of the expectation of the pixel raw-data output, is composed of a Poissonian part, modeling the photon sensing, and Gaussian ... | 18,784,024 |
The role of surveillance and data use in the development of public health policies. | Decision makers consider numerous factors besides surveillance data in establishing public health policies and programmes. In an evidence-informed system, it is important to collect, interpret, and present information that has maximum impact on the broader policy agenda.Successful policies and programmes are rational, ... | 18,784,050 |
Hunting happiness or promoting health? Why positive psychology deserves a place in health promotion. | This commentary asks the question of whether positive psychology represents an egoistic pursuit of happiness, which is in conflict with basic values within health promotion. A look at key concepts and research findings within positive psychology reveals common ground with health promotion. Similarities are evident in c... | 18,784,052 |
The structural basis for T-antigen hydrolysis by Streptococcus pneumoniae: a target for structure-based vaccine design. | Streptococcus pneumoniae endo-alpha-N-acetylgalactosaminidase is a cell surface-anchored glycoside hydrolase from family GH101 involved in the breakdown of mucin type O-linked glycans. The 189-kDa mature enzyme specifically hydrolyzes the T-antigen disaccharide from extracellular host glycoproteins and is representativ... | 18,784,084 |
10-year follow-up of intensive glucose control in type 2 diabetes. | During the United Kingdom Prospective Diabetes Study (UKPDS), patients with type 2 diabetes mellitus who received intensive glucose therapy had a lower risk of microvascular complications than did those receiving conventional dietary therapy. We conducted post-trial monitoring to determine whether this improved glucose... | 18,784,090 |
Early results for below-knee bypasses using Distaflo. | In patients who require lower extremity revascularization, prosthetic graft is a reasonable alternative in the absence of a suitable autologous vein conduit. However, prosthetic bypass grafts have limited patency, especially for infrageniculate reconstruction. Polytetrafluoroethylene grafts were geometrically modified ... | 18,784,116 |
Sympathetic and sensory nerve activation during negative pressure therapy of sternotomy wounds. | Negative pressure wound therapy (NPWT) has been adopted as the first-line treatment for poststernotomy mediastinitis as a result of the excellent clinical outcome. The knowledge concerning the effects of NPWT on the cardiovascular system and homeostasis is still limited. The aim of the present study was to investigate ... | 18,784,122 |
Endothelin--role in vascular disease. | It is now two decades since it was demonstrated that ET-1 is one of the most powerful vasoconstrictors in biology. ET-1 mediates its effects through two membrane G-protein coupled receptors, ET(A) and ET(B), which exhibit a wide tissue distribution including the endothelial cells, vascular smooth muscle cells and adven... | 18,784,133 |
Endothelin and scleroderma lung disease. | Scleroderma-associated interstitial lung disease (SSc-ILD) occurs frequently and for many patients SSc-ILD is a significant complication of their disease. SSc-ILD is now one of the leading causes of death among patients with SSc. SSc-ILD, classified most often as a non-specific interstitial pneumonia, may culminate in ... | 18,784,134 |
Adjustment of genomic waves in signal intensities from whole-genome SNP genotyping platforms. | Whole-genome microarrays with large-insert clones designed to determine DNA copy number often show variation in hybridization intensity that is related to the genomic position of the clones. We found these 'genomic waves' to be present in Illumina and Affymetrix SNP genotyping arrays, confirming that they are not platf... | 18,784,189 |
Study on the oxidative stress status among cement plant workers. | The cement industry is considered as a major pollution problem because of dust and particulate matter emitted at various steps of cement production. In the present study, volunteer male workers from a cement factory were studied for oxidative and nitrosative stress biomarkers in relation to their serum levels of alumin... | 18,784,198 |
Occupational ototoxicity of n-hexane. | The ability of chemicals to produce hearing loss themselves or to promote noise-induced hearing loss has been reported for some organic solvents. The objective of this study was to review the literature on the effects of low-level exposure to n-hexane on the auditory system and consider its relevance for occupational s... | 18,784,199 |
Whole-body CT trauma imaging with adapted and optimized CT angiography of the craniocervical vessels: do we need an extra screening examination? | Blunt carotid and vertebral artery injury (BCVI) is rare but potentially devastating. The objective of our study was to prospectively evaluate the usefulness of a dedicated and optimized CT angiography (CTA) protocol of the craniocervical vessels as part of a whole-body CT work-up of patients with multiple trauma in a ... | 18,784,210 |
Schistosomiasis and infection with human immunodeficiency virus 1 in rural Zimbabwe: systemic inflammation during co-infection and after treatment for schistosomiasis. | We previously reported that treatment for schistosomiasis in persons infected with human immunodeficiency virus 1 (HIV-1) attenuated HIV replication as measured by plasma HIV RNA. We investigated systemic inflammation as measured by plasma levels of soluble tumor necrosis factor-alpha receptor II (sTNF-rII), interleuki... | 18,784,223 |
Challenges in routine implementation and quality control of rapid diagnostic tests for malaria--Rufiji District, Tanzania. | Rapid diagnostic tests (RDTs) represent an alternative to microscopy for malaria diagnosis and have shown high sensitivity and specificity in a variety of study settings. Current World Health Organization (WHO) guidelines for quality control of RDTs provide detailed instructions on pre-field testing, but offer little g... | 18,784,230 |
Acute respiratory distress syndrome in a case of Plasmodium ovale malaria. | Acute respiratory distress syndrome is a well-known complication in Plasmodium falciparum infection. It is less frequently described in Plasmodium vivax, and only one case is reported in Plasmodium ovale. Here we present the second description of this pulmonary complication in a P. ovale acute infection. | 18,784,231 |
Distinctive epidemiologic and clinical features of common krait (Bungarus caeruleus) bites in Sri Lanka. | A prospective study was designed to define epidemiologic and clinical features of krait bites to improve diagnosis, management, and prevention. Among 762 cases of venomous snake bites admitted to 10 Sri Lankan hospitals in which the snake responsible was brought and identified, 88 (11.5%) were caused by common kraits (... | 18,784,244 |
Inducible rodent models of acquired podocyte diseases. | Glomerular diseases remain the leading cause of chronic and end-stage kidney disease. Significant advances in our understanding of human glomerular diseases have been enabled by the development and better characterization of animal models. Diseases of the glomerular epithelial cells (podocytes) account for the majority... | 18,784,259 |
Combined knockout of collecting duct endothelin A and B receptors causes hypertension and sodium retention. | The collecting duct (CD) endothelin (ET) system regulates blood pressure (BP) and Na excretion. CD-specific knockout (KO) of ET-1 causes hypertension, CD-specific KO of the ETA receptor does not alter BP, while CD-specific KO of the ETB receptor increases BP to a lesser extent than CD ET-1 KO. These findings suggest a ... | 18,784,261 |
Single-channel analysis of functional epithelial sodium channel (ENaC) stability at the apical membrane of A6 distal kidney cells. | Epithelial sodium channels (ENaC) play an essential role in maintaining total body fluid and electrolyte homeostasis. As such, abnormal expression of ENaC at the cell surface is linked to several important human diseases. Although the stability of ENaC subunits has been extensively studied by protein biochemical analys... | 18,784,262 |
Long-term retention explained by a model of short-term learning in the adaptive control of reaching. | Extensive theoretical, psychophysical, and neurobiological work has focused on the mechanisms by which short-term learning develops into long-term memory. Better understanding of these mechanisms may lead to the ability to improve the efficiency of training procedures. A key phenomenon in the formation of long-term mem... | 18,784,273 |
Different hormonal regulation of cellular differentiation and function in nucellar projection and endosperm transfer cells: a microdissection-based transcriptome study of young barley grains. | Nucellar projection (NP) and endosperm transfer cells (ETC) are essential tissues in growing barley (Hordeum vulgare) grains, responsible for nutrient transfer from maternal to filial tissues, endosperm/embryo nutrition, and grain development. A laser microdissection pressure catapulting-based transcriptome analysis wa... | 18,784,282 |
Presynaptic type III neuregulin 1 is required for sustained enhancement of hippocampal transmission by nicotine and for axonal targeting of alpha7 nicotinic acetylcholine receptors. | Both the neuregulin 1 (Nrg1) and alpha7 nicotinic acetylcholine receptor (alpha7*nAChRs) genes have been linked to schizophrenia and associated sensory-motor gating deficits. The prominence of nicotine addiction in schizophrenic patients is reflected in the normalization of gating deficits by nicotine self-administrati... | 18,784,291 |
A novel Na+ channel splice form contributes to the regulation of an androgen-dependent social signal. | Na(+) channels are often spliced but little is known about the functional consequences of splicing. We have been studying the regulation of Na(+) current inactivation in an electric fish model in which systematic variation in the rate of inactivation of the electric organ Na(+) current shapes the electric organ dischar... | 18,784,298 |
Identification of a novel nurr1-interacting protein. | The orphan nuclear receptor Nurr1 is required for the development of ventral mesencephalic dopaminergic neurons in mice. One of the possible mechanisms that might contribute to the regulation activity of Nurr1 is through interaction with other proteins. To identify potential partners of Nurr1, we screened a yeast two-h... | 18,784,308 |
Effects of a health behavior change model--based HIV/STI prevention intervention on condom use among heterosexual couples: a randomized trial. | This study examines an intervention for heterosexual couples to prevent human immunodeficiency virus/sexually transmitted infections. It also evaluates the effect of the intervention, which is based on current models of health behavior change, on intermediate outcomes (individual and relationship factors) and consisten... | 18,784,350 |
Effects of local mRNA structure on posttranscriptional gene silencing. | Antisense oligodeoxynucleotides (AONs) and short interfering RNAs (siRNAs) effect posttranscriptional gene silencing (PTGS) by hybridizing to an mRNA and then directing its cleavage. To understand the constraints that mRNA structure imposes on AON- vs. siRNA-mediated PTGS, AON- and siRNA-mediated cleavage of defined mR... | 18,784,366 |
[Vaginal birth after one previous cesarean section]. | To evaluate the frequency of different modes of delivery after one previous cesarean section and those factors which may influence mode of delivery. During the study period (1.1.2001-31.12.2005) 925 women with a previous cesarean section and a following singleton pregnancy were identified and included. Information rega... | 18,784,385 |
Striated myogenesis and peristalsis in the fetal murine esophagus occur without cell migration or interstitial cells of Cajal. | Esophageal striated myogenesis progresses differently from appendicular myogenesis, but the mechanism underlying this process is incompletely understood. Early theories of transdifferentiation of smooth muscle into striated muscle are not supported by transgenic fate-mapping experiments; however, the origin of esophage... | 18,784,410 |
Respiratory muscle strength predicts decline in mobility in older persons. | To test the hypothesis that respiratory muscle strength is associated with the rate of change in mobility even after controlling for leg strength and physical activity. Prospective study of 890 ambulatory older persons without dementia who underwent annual clinical evaluations to examine change in the rate of mobility ... | 18,784,416 |
Monitoring neonatal regional cerebral oxygen saturation in clinical practice: value and pitfalls. | This review focuses on the clinical use of near infrared spectroscopy (NIRS) to assess brain oxygenation by the tissue oxygenation index (TOI), and monitoring regional cerebral oxygen saturation (rScO(2)), cerebral fractional tissue oxygen extraction (cFTOE), which is derived from rScO(2), and systemic oxygen saturatio... | 18,784,420 |
Endobronchial obstruction from an intubation stylet sheath. | Many clinicians intubate newborns using a stylet, but how many always check if the device is intact after use? We describe a case of endobronchial obstruction by a plastic sheath coating the metal stylet, and suggest ways to reduce the incidence of this serious iatrogenic complication. | 18,784,428 |
Resolution of severe macular edema in adult coats' disease with intravitreal triamcinolone and bevacizumab injection. | A 47 year old male patient visited our hospital with the chief complaint of deterioration of the visual acuity in the left eye. The fundus examination revealed thick hard exudates, multiple aneurysms and telangiectasias of the retinal vessels in the posterior pole. Fluorescein angiography demonstrated massive leakage o... | 18,784,449 |
Early mortality among adults accessing antiretroviral treatment programmes in sub-Saharan Africa. | Two-thirds of the world's HIV-infected people live in sub-Saharan Africa, and more than 1.5 million of them die annually. As access to antiretroviral treatment has expanded within the region; early pessimism concerning the delivery of antiretroviral treatment using a large-scale public health approach has, at least in ... | 18,784,453 |
Evaluation of the influence of location of osseointegrated implants associated with mandibular removable partial dentures. | The aim of this research was to assess, by means of, the bi-dimensional finite element method, the best implant location in the alveolar edge, through stress distribution and support structure displacement of a distal extension removable partial denture associated with an osseointegrated implant of 10.0 x .75 mm, actin... | 18,784,528 |
Scanning electron microscope evaluation of vertical and horizontal discrepancy in cast copings for single-tooth implant-supported prostheses. | Despite careful attention to waxing, investing, and casting, marginal discrepancies are inevitable. Vertical and horizontal discrepancies can result in crestal bone resorption, peri-implantitis, and loss of osseointegration. The aim of this study was to evaluate marginal gap and overhang in 3 casting techniques for imp... | 18,784,530 |
Sinus augmentation complications: etiology and treatment. | Sinus augmentation, either osteotome or lateral window approach, is a predictable procedure to augment vertical height that allows for proper implant placement in areas with previous limited restorative options. Like any surgical procedures, there is always a risk of encountering either intrasurgical or postsurgical co... | 18,784,534 |
The relationship between attorney involvement, claim duration, and workers' compensation costs. | To determine the relationship between attorney involvement, claim duration and workers' compensation claim costs. We identified and compared 738 claims with attorney involvement and 6191 claims without attorney involvement submitted by individuals injured between August 1, 2003 and July 31, 2004 whose claims were paid ... | 18,784,549 |
Rotator cuff syndrome: personal, work-related psychosocial and physical load factors. | To identify factors associated with rotator cuff syndrome (RCS) among active workers. Seven hundred thirty-three workers in 12 worksites participated in a cross-sectional study with individual structured physical and psychosocial health interviews, physical examinations, and exposure assessments of biomechanical factor... | 18,784,555 |
Hepatoprotection and lethality rescue by histone deacetylase inhibitor valproic acid in fatal hemorrhagic shock. | Pharmacological histone deacetylase (HDAC) inhibitors, such as known anticonvulsant valproic acid (VPA), demonstrate cytoprotective effects and increase acetylation of nuclear histones, promoting transcriptional activation of deregulated genes. Therefore, we examined protective effects of VPA administration in lethal h... | 18,784,568 |
Postmortem computed tomography as an adjunct to autopsy for analyzing fatal motor vehicle crash injuries: results of a pilot study. | Detailed fatal injury data after fatal motor vehicle crashes (MVC) are necessary to improve occupant safety and promote injury prevention. Autopsy remains the principle source of detailed fatal injury data. However, procedure rates are declining because of a range of technical, ethical, and religious concerns. Postmort... | 18,784,581 |
Intramedullary fixation of failed plated femoral diaphyseal fractures: are bone grafts necessary? | Nonunited fracture shaft femur after plate fixation is a common problem in third world countries because of economic reasons. Management of such a problem is still controversial and is associated with many surgical details, due not only to the nonunited fracture itself, but also to the broken implant which is not easy ... | 18,784,586 |
Blunt solid organ injury: do adult and pediatric surgeons treat children differently? | The management of blunt solid organ injury (SOI) in children may differ depending on the treating facility. These differences, however, may not reflect the individual surgeon's treatment philosophy. To investigate differences in management, adult and pediatric surgeons were presented the same hypothetical pediatric tra... | 18,784,587 |
Subpopulation estimates from the HIV incidence surveillance system--United States, 2006. | CDC has created an HIV incidence surveillance system in selected areas of the United States as a component of its national human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) reporting system. The purpose of the new system is to estimate the number of new HIV infections occurring each year in the... | 18,784,639 |
Recent Arctic warming vertical structure contested. | The vertical structure of the recent Arctic warming contains information about the processes governing Arctic climate trends. Graversen et al. argue, on the basis of ERA-40 reanalysis data, that a distinct maximum in 1979-2001 warm-season (April-October) Arctic temperature trends appears around 3 km above ground. Here ... | 18,784,660 |
A Mott insulator of fermionic atoms in an optical lattice. | Strong interactions between electrons in a solid material can lead to surprising properties. A prime example is the Mott insulator, in which suppression of conductivity occurs as a result of interactions rather than a filled Bloch band. Proximity to the Mott insulating phase in fermionic systems is the origin of many i... | 18,784,720 |
Upward migration of Vesuvius magma chamber over the past 20,000 years. | Forecasting future eruptions of Vesuvius is an important challenge for volcanologists, as its reawakening could threaten the lives of 700,000 people living near the volcano. Critical to the evaluation of hazards associated with the next eruption is the estimation of the depth of the magma reservoir, one of the main par... | 18,784,723 |
Microalbuminuria: do we need a new threshold? | Microalbuminuria (30-300 mg of albumin/24 h) is a well-known independent risk factor for kidney and cardiovascular disease and of mortality in diabetic, hypertensive and in the general population. However, recent studies indicate that increased risk is observed at levels of albuminuria much lower than those currently e... | 18,784,737 |
CSB protein is (a direct target of HIF-1 and) a critical mediator of the hypoxic response. | Cockayne syndrome (CS) is a rare genetic disease characterized by neurological problems, growth failure and premature ageing. Many of these features cannot simply be ascribed to the defect that CS cells display during transcription-coupled repair. Here, we show that CSB mutant cells are unable to react to hypoxic stimu... | 18,784,753 |
The influence of predation on the chronic response of Artemia sp. populations to a toxicant. | Environmental risk assessment of contaminants is conventionally based on toxic effects assessed in organism-level test systems. We suggest that, for the prediction of toxicant effects, population- and community-level effects should be considered. The aim of this study was to investigate how predation could alter a prey... | 18,784,796 |
Molecular beacons in biomedical detection and clinical diagnosis. | Among the diverse nucleic acid probes, molecular beacons (MBs) have shown their excellent potential in a variety of basic researches and practical applications. Their excellent selectivity, sensitivity, and detection without separation have led them to be particularly useful in real-time intracellular monitoring of gen... | 18,784,800 |
Prognostic significance of flow cytometric immunophenotyping in acute myeloid leukemia. | The prognostic significance of flow cytometric immunophenotyping (FCI) in acute myeloid leukemia (AML) has been controversial. In this study, we re-investigated the possible role of FCI in the prediction of AML relapse following standard chemotherapy. A total of 209 AML cases with follow-up information were analyzed. A... | 18,784,805 |
HIV-1 TAT inhibits microglial phagocytosis of Abeta peptide. | Human immunodeficiency virus (HIV)-associated dementia (HAD) is a subcortical neuropsychiatric syndrome that has increased in prevalence in the era of highly active antiretroviral therapy (HAART). Several studies demonstrated increased amyloidosis in brains of HIV patients and suggested that there may be a significant ... | 18,784,813 |
C-MYC rearrangements are frequent in aggressive mature B-Cell lymphoma with atypical morphology. | Diagnosis and classification of aggressive mature B-cell lymphoma with atypical morphology remains a challenge. To identify factors that may contribute to the atypical morphology, we selected eight such cases and evaluated their morphologic, immunophenotypic and cytogenetic features and clinical outcomes. The neoplasti... | 18,784,824 |
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