title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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Early and extended early bactericidal activity of linezolid in pulmonary tuberculosis. | Linezolid, the first oxazolidinone approved for clinical use, has effective in vitro and promising in vivo activity against Mycobacterium tuberculosis. To evaluate the early and extended early bactericidal activity of linezolid in patients with pulmonary tuberculosis. Randomized open label trial. Thirty patients with n... | 18,787,216 |
Lung function in infants with cystic fibrosis diagnosed by newborn screening. | Progressive lung damage in cystic fibrosis (CF) starts in infancy, and early detection may aid preventative strategies. To measure lung function in infants with CF diagnosed by newborn screening and describe its association with pulmonary infection and inflammation. Infants with CF (n = 68, 6 weeks to 30 months of age)... | 18,787,217 |
Sign language recognition by combining statistical DTW and independent classification. | To recognize speech, handwriting or sign language, many hybrid approaches have been proposed that combine Dynamic Time Warping (DTW) or Hidden Markov Models (HMM) with discriminative classifiers. However, all methods rely directly on the likelihood models of DTW/HMM. We hypothesize that time warping and classification ... | 18,787,250 |
Changes in h-reflex amplitude during massage of triceps surae in healthy subjects. | The purpose of this study was to investigate the effects of massage on neuromuscular excitability, as measured by changes in Hoffmann reflex (H-reflex) amplitudes. Nine healthy subjects (= 25.2 years; 2 males, 7 females), with no history of neurological disease, participated in the study. H-reflexes were elicited from ... | 18,787,257 |
Shoulder kinesthesia after anterior glenohumeral joint dislocation. | This article was presented in poster format at the Sixty-Third Annual Conference of the American Physical Therapy Association, San Antonio, TX, June 28-July 2,1987. The study was supported in part by the Montana Chapter of the American Physical Therapy Association and was submitted June 24, 1987; was with the authors f... | 18,787,264 |
Treatment of hepatocellular carcinoma. | Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world, and is the third highest cause of cancer-related mortality. HCC usually develops in patients with chronic liver disease, particularly in those who also have cirrhosis. The possibility of curative treatment depends on both the stage of tumor an... | 18,787,282 |
Drug-eluting stent treatment of a radiation-induced left internal mammary arterial graft stenosis. | A 62-year-old man underwent radiotherapy to the left upper chest for treatment of Pancoast syndrome on a background of previous coronary artery bypass grafting 12 years earlier. Within 1 year, he developed significant stenoses of both the left internal mammary artery (LIMA) graft and ostial left vertebral artery, presu... | 18,787,292 |
A 32-kDa tyrosine-phosphorylated protein shows a protease-dependent increase in dead boar spermatozoa. | Boar sperm TyrP32 is a 32-kDa tyrosine-phosphorylated protein that increases during the capacitation and acrosome reaction and during cryocapacitation. However, it is still unclear whether the increase in TyrP32 is an event that is limited to the process of sperm fertilization, including cryocapacitation. The aims of t... | 18,787,309 |
[Determination of gossypol in feeds by HPLC]. | An HPLC method for determination of goosypol in feed was developed. Gossypol in food was extracted with acetic acid-water-phosphoric acid (85 : 15 : 1) for 20 min in a water bath at 100 degrees C. The extract was diluted with acetone-water (1 : 1), and injected into the HPLC. HPLC was performed with a Shodex C18M4E (4.... | 18,787,315 |
Comparative effects of home- and group-based exercise on balance confidence and balance ability in older adults: cluster randomized trial. | Exercise can modify fall risk factors such as balance and mobility impairments. However, can exercise improve balance confidence? In one strength-training study, researchers reported that a change in balance confidence was not uniformly associated with changes in objective measures of fall risk or physical performance.... | 18,787,321 |
Effect of phototherapy on neonatal heart rate variability and complexity. | Phototherapy is a common mode of treatment for neonatal hyperbilirubinemia. However, phototherapy has been reported to alter cardiovascular function by causing increased peripheral blood flow, diminished cardiac output and increased sympathetic activity that may be of concern particularly in sick or premature newborns.... | 18,787,336 |
Accumulation of CD8+CD45RA+CD62L+ T cells in acute chylothorax in neonates. | Acute chylothorax in neonates is a rare disease but results in significant loss of lymphatic cells. The purpose of the study was to determine whether acute chylothorax in neonates results in quantitative changes of lymphocyte subpopulations in peripheral blood and chyle. 6 neonates who had acute chylothorax after thora... | 18,787,342 |
Integrated analysis of copy number alterations and loss of heterozygosity in human pancreatic cancer using a high-resolution, single nucleotide polymorphism array. | To chart molecular genetic events in pancreatic cancer. We analyzed genome-wide copy number alterations and loss of heterozygosity (LOH) in 25 established pancreatic cancer cell lines using a high-density single nucleotide polymorphism (SNP) array. We verified the data using genomic PCR and applied them to clinical sam... | 18,787,345 |
Concurrent chemoradiotherapy with weekly paclitaxel in malignant cerebral glioma treatment. | Anaplastic astrocytomas (AA) and glioblastomas (GB) are the most common malignant gliomas, and despite newly developed drugs and combined treatments, they still have an adverse prognosis. Paclitaxel is a cytotoxic agent with radiosensitizing properties and exerts objective growth inhibition in glioma tumor cells. From ... | 18,787,350 |
Long-term survival of a patient with small cell lung cancer after nine lines of chemotherapy and radiation. | Small cell lung cancer (SCLC) results in death within 1-2 months if left untreated. Although therapeutic standards only comprise first- and second-line chemotherapy due to poor prognosis, a subset of patients may warrant a trial of further chemotherapy, as demonstrated in the following case. We present a 52-year-old ma... | 18,787,355 |
Primary amelanotic melanoma of the vagina. | Primary malignant melanoma of the vagina is extremely rare, accounting for 0.3-0.8% of all malignant melanomas. True amelanotic vaginal melanoma showing no melanin on histological examination is exceedingly rare, accounting for only 2% of all vaginal melanomas. We describe a 31-year-old female patient who presented wit... | 18,787,356 |
Cannabis-induced psychotic-like experiences are predicted by high schizotypy. Confirmation of preliminary results in a large cohort. | Cannabis use has been identified as a possible risk factor for developing schizophrenia. In a previous paper we reported preliminary evidence that cannabis use increases the likelihood of psychosis-like experiences in non-clinical respondents who scored highly on a measure of schizotypy. We now present findings from po... | 18,787,359 |
Reference values for neonatal thyroid volumes in a moderately iodine-deficient area. | The reference ranges of thyroid volumes in neonates vary according to the iodine status of a specific region. In different studies, it ranged between 0.47 and 1.62 ml. It has been previously shown that Bursa city was a moderately iodine-deficient area. We therefore aimed at determining normal reference ranges of neonat... | 18,787,384 |
The fold recognition of CP2 transcription factors gives new insights into the function and evolution of tumor suppressor protein p53. | The CP2 transcription factor (TFCP2) is a critical regulator of erythroid gene expression. Apart from the involvement in the transcriptional switch of globin gene promoters it activates an array of cellular and viral gene promoters. A number of homologous proteins was identified in genomes of Metazoa, with additional f... | 18,787,404 |
Stromal SPARC expression and patient survival after chemoradiation for non-resectable pancreatic adenocarcinoma. | Pancreatic stellate cells (PSC) drive desmoplasia in pancreatic cancer. Our study analyzed both tumor and PSC, since interaction of these cell types may promote tumor progression. SPARC was expressed predominantly in the peritumoral and distal stroma. SPARC in distal stroma correlated inversely with overall survival of... | 18,787,407 |
Emerging functions of c-kit and its ligand stem cell factor in dendritic cells: regulators of T cell differentiation. | The receptor tyrosine kinase, c-kit, and its ligand, stem cell factor (SCF), function in a diverse range of biological functions. The role of c-kit in the maintenance and survival of hematopoietic stem cells and of mast cells is well recognized. c-kit also plays an important role in melanogenesis, erythropoiesis and sp... | 18,787,413 |
Comedo-ductal carcinoma in situ: A paradoxical role for programmed cell death. | Comedo-DCIS is a histologic subtype of preinvasive breast neoplasia that is characterized by prominent apoptotic cell death and has greater malignant potential than other DCIS subtypes. We investigated the mechanisms of apoptosis in comedo-DCIS and its role in conversion of comedo-DCIS to invasive cancer. Clinical come... | 18,787,417 |
Immuno-localization of CD44 and osteopontin in developing human kidney. | CD44 is observed in ureteric bud structures and is implicated in branching morphogenesis during early mouse renal development. Healthy adult kidney demonstrates minimal CD44, but CD44 is up-regulated in renal diseases. CD44 may mediate binding of calcium oxalate crystals to tubular epithelia via the ligands osteopontin... | 18,787,423 |
Can outcome prediction data change patient outcomes and organizational outcomes? | Intensive care medicine consumes a high share of healthcare costs, and there is growing pressure to use the scarce resources efficiently. Accordingly, organizational issues and quality management have become an important focus of interest in recent years. Here, we will review current concepts of how outcome data can be... | 18,787,442 |
Update on ventricular assist device management in the ICU. | Mechanical circulatory support has a progressively increasing impact in the treatment of heart failure. The results of mechanical circulatory support are limited not only by the severity of the disease, which necessitated initiation of support, but also by the serious device-related adverse events. Optimized patient se... | 18,787,451 |
CARD15 gene polymorphisms in Serbian patients with Crohn's disease: genotype-phenotype analysis. | Genetic heterogeneity and incomplete phenotype penetrance complicate genetic analysis of Crohn's disease (CD). Studies in western Europe have shown that CARD15 polymorphisms increase susceptibility to CD, but frequencies vary within different European populations. The aim here was to evaluate the prevalence of CARD15 m... | 18,787,464 |
The sentinel node technique is useful for studies of intestinal immunology in inflammatory bowel disease patients. | Mesenteric lymph nodes may play a crucial role in the pathogenesis of human inflammatory bowel disease. We have used the sentinel node technique to analyze mesenteric lymph nodes draining inflammatory lesions sentinel nodes and corresponding site of inflamed bowel in patients with ulcerative colitis or Crohn's disease.... | 18,787,465 |
Assessment of 'nucleation time' as a predictor of cholelithiasis. | In the formation of gallstones, crystal nucleation is a key step, which is followed by precipitation and gradual growth of cholesterol crystals. A case-control study was carried out among 60 patients (30 patients, 14 males and 16 females, median age of 36 years, range 33-71 years, body mass index (BMI)=25.1+/-0.33 kg/m... | 18,787,471 |
Muscle and nerve responses after different intervals of electrical stimulation sessions on denervated rat muscle. | Electrical stimulation is a procedure used to treat denervated muscles. The number of electrical stimulation sessions varies across muscle rehabilitation protocols, from daily to certain days throughout the week. The purpose of this study was to evaluate how muscle and nerve respond to different intervals of electrical... | 18,787,495 |
Laparoscopic adrenalectomy. | Laparoscopic adrenalectomy (LA) is the gold standard for the surgical management of small and medium adrenal masses. Nevertheless, there is still controversy for the laparoscopic treatment of adrenal carcinoma. The aim of this article was to report current standards on LA. The data for this review were obtained by a Pu... | 18,787,512 |
The effects of a 6-month sodium restriction on cardiac autonomic function in patients with mild to moderate essential hypertension. | The blood pressure-lowering mechanism of low-sodium diet is not fully understood. We assessed the effects of salt restriction on cardiac parasympathetic function as measured by heart-rate variability (HRV) in mild to moderate hypertensive patients. Eighty patients were randomized to a 6-month low- (N = 40) or normal (N... | 18,787,516 |
Balancing early market access to new drugs with the need for benefit/risk data: a mounting dilemma. | Drug regulatory agencies are increasingly pressed by the challenge of finding the appropriate balance between the need for rapid access to new drugs and the need to ensure comprehensive data on their benefits and risks. This dilemma is not new, but has been made more prominent by recent high-profile drug withdrawals an... | 18,787,530 |
[Elderly patients with chronic pain]. | Chronic pain is a serious and frequent health problem in elderly people. We have assessed main characteristics of chronic pain in elderly patients referred to a Norwegian multidisciplinary pain clinic. Medical records were assessed for patients with chronic pain who were at least 60 years old (n = 48) and treated at th... | 18,787,596 |
Cerebral ventricular volume and temperamental difficulties in infancy. The Generation R Study. | Numerous studies have provided evidence for subtle deviations in brain morphology in children with psychiatric disorders, but much less is known about the onset and developmental trajectory of these deviations early in life. We sought to determine whether variances in cerebral ventricular size in fetuses and newborns a... | 18,787,659 |
Top-down analysis of temporal hierarchy in biochemical reaction networks. | The study of dynamic functions of large-scale biological networks has intensified in recent years. A critical component in developing an understanding of such dynamics involves the study of their hierarchical organization. We investigate the temporal hierarchy in biochemical reaction networks focusing on: (1) the eluci... | 18,787,685 |
Is mate choice in humans MHC-dependent? | In several species, including rodents and fish, it has been shown that the Major Histocompatibility Complex (MHC) influences mating preferences and, in some cases, that this may be mediated by preferences based on body odour. In humans, the picture has been less clear. Several studies have reported a tendency for human... | 18,787,687 |
Antibodies against a surface protein of Streptococcus pyogenes promote a pathological inflammatory response. | Streptococcal toxic shock syndrome (STSS) caused by Streptococcus pyogenes is a clinical condition with a high mortality rate despite modern intensive care. A key feature of STSS is excessive plasma leakage leading to hypovolemic hypotension, disturbed microcirculation and multiorgan failure. Previous work has identifi... | 18,787,689 |
Acute and chronic effects of continuous positive airway pressure therapy on left ventricular systolic and diastolic function in patients with obstructive sleep apnea and congestive heart failure. | Obstructive sleep apnea (OSA) may contribute to the pathogenesis of congestive heart failure (CHF). Nocturnal continuous positive airway pressure (CPAP) therapy can alleviate OSA and may have a role in the treatment of CHF patients. To investigate the acute and chronic effects of CPAP therapy on left ventricular systol... | 18,787,720 |
Second recurrence of familial cardiac myxomas in atypical locations. | Recurrence rates reported for cardiac myxomas are 4% to 7% for sporadic cases and 10% to 21% for familial cases. Although recurrence rates are high, second recurrences are rare. Familial cardiac myxomas in a mother and daughter are reported, both of whom had their second recurrences within six years. Both had recurrenc... | 18,787,723 |
Abdominal obesity and the metabolic syndrome: a surgeon's perspective. | Over the past decade, a major shift in the clinical risk factors in the population undergoing a cardiac surgery has been observed. In the general population, an increasing prevalence of obesity has largely contributed to the development of cardiovascular disorders. Obesity is a heterogeneous condition in which body fat... | 18,787,732 |
Clinical and microbiological characteristics of mycotic aneurysms in a medical center in southern Taiwan. | Mycotic aneurysm poses a high risk of mortality. This study evaluated the demographic and clinical characteristics and outcomes of hospitalized patients with mycotic aneurysm. Patients with mycotic aneurysm hospitalized between March 1996 and May 2006 at a medical center in southern Taiwan were retrospectively analyzed... | 18,787,739 |
Perceived need for mental health care among non-western labour migrants. | There is a supposed higher prevalence of common mental disorders among many migrant groups. At the same time, problems are reported regarding underutilisation of mental health services by migrants. Since perceived need for care is a powerful predictor of actual care utilisation, we aimed to study the hypothesis that, g... | 18,787,746 |
Effect of blood brain barrier permeability in recurrent high grade gliomas on the intratumoral pharmacokinetics of methotrexate: a microdialysis study. | Determining whether potentially therapeutic drug exposure is achieved within brain tumors in an exploratory clinical investigation would provide a rational basis for selecting agents for evaluation in phase II trials. This study investigated the use of microdialysis to assess intratumoral drug distribution in patients ... | 18,787,762 |
New antimicrobial drug resistance and epidemiological typing patterns of Staphylococci from clinical isolates and raw meats. | The antimicrobial susceptibilities of Staphylococcus isolated from clinical isolates and raw meats were tested for six different antimicrobial agents that are in widespread clinical use in Korea and four new antimicrobials, linezolid, quinupristin/dalfopristin, daptomycin, and tigecycline. And this study analyzed the m... | 18,787,791 |
Characterization of monolithic matrix patch system containing tulobuterol. | The aim of this study was to investigate the effect of the functional groups in acrylic adhesive on tulobuterol uptake, release rate and permeation rate across rat dorsal skin. In addition, the relationship between these parameters was identified in order to formulate the monolithic matrix patch system. Seven acrylate ... | 18,787,793 |
Analysis of acamprosate in beagle dog plasma by LC-MS-MS. | A rapid, sensitive, and specific analytical method was developed and validated to quantify acamprosate calcium in beagle dog plasma. The method employs a single plasma protein precipitation, and the analytes are separated by chromatography on an Acquity UPLC HSS T3 column and analyzed by mass spectrometry in the multip... | 18,787,794 |
Protective effect of morin on the imipenem-induced nephrotoxicity in rabbits. | The present study investigated the protective effect of morin, a natural flavonoid, on the imipenem-induced nephrotoxicity in rabbits. Nephrotoxicity of imipenem was examined after the intravenous administrations of imipenem (200 mg/kg) to rabbits in the presence and the absence of morin (12, 25, 50 mg/kg, p.o.). Cytot... | 18,787,798 |
Angiotensin-converting enzyme D allele does not influence susceptibility to acute hypoxic respiratory failure in children. | The D allele of the I/D polymorphism in the angiotensin-converting enzyme (ACE) gene has been associated with an increased risk of ARDS in critically ill adults and severity of bronchopulmonary dysplasia in pre-term infants. We hypothesised that the presence of the hypoxia-associated ACE D allele would increase suscept... | 18,787,808 |
Plasmablastic lymphoma: CNS involvement, coexistence of other malignancies, possible viral etiology, and dismal outcome. | The clinical and pathological findings of plasmablastic lymphoma (PBL) have been described in the literature but the etiology is not well established, and treatment options are poorly defined. We reviewed patients with PBL in our institution to characterize the clinicopathologic features in our patient population. In t... | 18,787,825 |
Nonlinear simulations of solid tumor growth using a mixture model: invasion and branching. | We develop a thermodynamically consistent mixture model for avascular solid tumor growth which takes into account the effects of cell-to-cell adhesion, and taxis inducing chemical and molecular species. The mixture model is well-posed and the governing equations are of Cahn-Hilliard type. When there are only two phases... | 18,787,827 |
Multiscale agent-based cancer modeling. | Agent-based modeling (ABM) is an in silico technique that is being used in a variety of research areas such as in social sciences, economics and increasingly in biomedicine as an interdisciplinary tool to study the dynamics of complex systems. Here, we describe its applicability to integrative tumor biology research by... | 18,787,828 |
Implantation of retropupillar iris claw lenses with and without combined penetrating keratoplasty. | For aphakic patients without lens-supporting apparatus, secondary lens implantation can be considered. Literature on retropupillar iris claw lens implantation as a safe alternative to scleral fixated posterior chamber lenses is scarce. The study included 22 patients. In ten cases, an iris claw lens was implanted retrop... | 18,787,833 |
[Health protection from an ethical point of view]. | Illness and health are terms open to interpretation. Their meaning depends on cultural backgrounds, societal designations and historical change. During the modern era, having been shaped by natural sciences, knowledge in medicine has grown exponentially. However, critical voices warn of a medicalization of the image of... | 18,787,857 |
Effect of tiotropium on cough reflex sensitivity in acute viral cough. | Cough is the most common complaint for which patients in the United States seek medical attention. Few, if any, effective therapies exist for the most common form of acute cough, that due to viral upper respiratory tract infection (URI). The aim of this study was to evaluate the effect of the anticholinergic agent tiot... | 18,787,899 |
Tracheobronchopathia osteochondroplastica: a rare large airway disorder. | Tracheobronchopathia osteochondroplastica (TO) is a rare disorder of the large airways characterized by the development of submucosal cartilaginous and bony nodules. The nodules involve the anterior and lateral walls and typically spare the posterior membranous wall. The clinical presentation of TO is variable and rang... | 18,787,900 |
Missed opportunities in diabetes management: a longitudinal assessment of factors associated with sub-optimal quality. | In diabetic adults, tight control of risk factors reduces complications. To determine whether failure to make visits, monitor risk factors, or intensify therapy affects control of blood pressure, glucose, and lipids. A non-concurrent, prospective study of data from electronic files and standardized abstraction of hard-... | 18,787,908 |
From "us vs. them" to "shared risk": can animals help link environmental factors to human health? | Linking human health risk to environmental factors can be a challenge for clinicians, public health departments, and environmental health researchers. While it is possible that nonhuman animal species could help identify and mitigate such linkages, the fields of animal and human health remain far apart, and the prevail... | 18,787,924 |
Pharmacodynamic evaluation of oral estradiol nanoparticles in estrogen deficient (ovariectomized) high-fat diet induced hyperlipidemic rat model. | It is believed that estrogen deficiency contributes importantly to the pathogenesis of menopausal metabolic syndrome and symptoms can be ameliorated with estradiol therapy. The present study reports efficacy of 17-beta estradiol encapsulated nanoparticles in treating the postmenopausal dyslipidemic condition. Estradiol... | 18,787,933 |
Do faces capture the attention of individuals with Williams syndrome or autism? Evidence from tracking eye movements. | The neuro-developmental disorders of Williams syndrome (WS) and autism can reveal key components of social cognition. Eye-tracking techniques were applied in two tasks exploring attention to pictures containing faces. Images were (i) scrambled pictures containing faces or (ii) pictures of scenes with embedded faces. Co... | 18,787,936 |
Factors influencing long-term follow-up clinic attendance among survivors of childhood cancer. | Attendance at long-term follow-up clinic is necessary for survivors of childhood cancer to facilitate education about cancer-related health risks, early detection of treatment-related morbidity, and implementation of health-promoting interventions. Despite the need for continued care, barriers to clinic attendance exis... | 18,787,958 |
Reversal of Brugada electrocardiographic pattern with sodium bicarbonate solution after amitriptyline overdose. | A Brugada electrocardiographic pattern (BEP) associated with tricyclic antidepressant (TCA) overdose has been reported rarely, but its reversal by sodium bicarbonate has not been described previously. We reported a case of amitriptyline overdose induced Type 1 BEP which was reversed by 150 mEq of intravenous sodium bic... | 18,788,005 |
Functional consequences of retinopetal fibers originating in the dorsal raphe nucleus. | The existence of centrifugal fibers projecting into the mammalian retina is well known. However, their precise physiological role is poorly understood. Here we report that stimulation of the dorsal raphe nucleus (DRN) in freely moving rats produces profound effects on the electroretinogram (ERG). Most notably, activati... | 18,788,023 |
Verbal working memory dysfunction in schizophrenia: an FMRI investigation. | Impaired processing of working memory information is one of the cognitive deficits seen in patients with schizophrenia. This study aims at corroborating the differences in the brain activities involved in the process of working memory between patients with schizophrenia and the controls. Twelve patients with schizophre... | 18,788,030 |
Volumizing effect of a new hyaluronic acid sub-dermal facial filler: a retrospective analysis based on 102 cases. | Many signs of aging are due to the loss of subcutaneous fat. Dermal fillers are non-surgical cosmetic treatments used to restore facial volume. Voluma is a new hyaluronic acid sub-dermal facial filler. The objective of this study was to assess its effectiveness in maintaining increased volume for up to 18 months post-t... | 18,788,032 |
Treatment with aspirin and dipyridamole is more effective than aspirin in reducing low shear blood viscosity. | Investigate effects of aspirin/dipyridamole and aspirin on blood viscosity (BV) in subjects with hyperhomocystememia (>14 micromol/L) and stable cardiovascular disease (CVD) or >or= 20% risk for CVD were the aims of this study. Forty-seven subjects were treated with 14 days of either aspirin/dipyridamole (25 mg/2... | 18,788,038 |
Synthesis of simple adenosine diphosphate ribose analogues. | [See figures]. The synthesis of analogues of adenosine diphosphate ribose and acetylated adenosine diphosphate ribose, modified at the northern pentose, is reported. The stereochemistry at the acetylated centers was chosen to minimize acetyl migration and dictated the overall synthetic strategy. | 18,788,043 |
Extraocular muscle cysticercosis: clinical features and management outcome. | Extraocular muscle cysticercosis is rare and can be classified based on the stage of evolution as viable, degenerating, and inactive. A tailored approach to therapy using a combination of albendazole and steroids has been proposed. In this study, we have evaluated the clinical features and response of "viable" extraocu... | 18,788,057 |
Application of negative ion MS/MS to the identification of N-glycans released from carcinoembryonic antigen cell adhesion molecule 1 (CEACAM1). | Structures of N-glycans released from rat CEACAM1 expressed in human embryonic kidney cells were determined by MALDI and negative ion nanospray MS/MS techniques. The major carbohydrates were bi-, tri- and tetra-antennary complex glycans with and without sialic acid, fucose and bisecting GlcNAc residues. High-mannose gl... | 18,788,072 |
Mechanisms and sequelae of E-cadherin silencing in hereditary diffuse gastric cancer. | Around 25-40% of cases of hereditary diffuse gastric cancer (HDGC) are caused by heterozygous E-cadherin (CDH1) germline mutations. The mechanisms for loss of the second allele still remain unclear. The aims of this study were to elucidate mechanisms for somatic inactivation of the wild-type CDH1 allele and to seek evi... | 18,788,075 |
Analysis of Hispanic representation and conceptualization in psychology and law research. | Hispanics are now the largest minority group in the United States, yet research examining the impact this will have on the American legal system is limited. The first purpose of this article was to synthesize the studies that have been conducted, which have found that Hispanics have a perspective toward the police, the... | 18,788,079 |
Amyloidosis and diabetes in humans. | The relationship between amyloidosis and diabetes mellitus has been investigated with special regard to the islets of Langerhans. Little information is available in the literature about the relationship between diabetes mellitus and extrainsular amyloidosis. New data on the nature of amyloid and particularly its separa... | 18,788,149 |
Immunohistochemical study of secretory component, secretory IgA and carcinoembryonic antigen in large bowel carcinomas. | The epithelium of 41 large bowel carcinomas was scored immunohistochemically on a semiquantitative basis for the presence of secretory component (SC), secretory IgA, and carcinoembryonic antigen (CEA). Both the tumour and the adjacent "transitional mucosa" were evaluated. The various immunofluorescence scores obtained,... | 18,788,158 |
Hemangioendothelioma of the thyroid gland--true endothelioma or anaplastic carcinoma? | After a critical histological re-examination of 26 cases of malignant hemangioendothelioma of the thyroid, and a comparison with 51 cases of anaplastic spindle and giant cell carcinoma, it becomes obvious that traumatic and shrinkage artefacts due to fixation, as well as superimposition of neoplastic and repair process... | 18,788,166 |
Sarcoma botryoides of the extrahepatic bile ducts. A light- and electron microscopic study of a case. | The clinical, light- and electron microscopic features of a sarcoma botryoides of the common bile duct of a 2 1/2-year-old boy are reported. Despite the absence of cross-striation under the light microscope, many tumour cells were found to contain abundant thin and thick filaments arranged in a sarcomere-like pattern a... | 18,788,169 |
Public-private collaboration to improve oral health status of children enrolled in Head Start in New York City. | A comprehensive oral health care program for Head Start children in New York City is described. Head Start is a federally funded pre-school program for low-income families and their children. It provides activities that help children grow mentally, socially, emotionally and physically. In 1994, a public-private partner... | 18,788,178 |
Ixodid ticks on dogs belonging to people in rural communities and villages in Maputo Province, Mozambique. | The species composition and geographic distribution of ixodid ticks infesting domestic dogs owned by people in rural communities and villages in Maputo Province was established by collecting ticks from dogs at each of 27 localities spread throughout the province. Ticks were collected from a total of 132 dogs, and nine ... | 18,788,203 |
Acute and long-term effects of exposure to sodium monofluoroacetate (1080) in sheep. | Acute and long-term effects of a single, relatively high oral dose (0.25 and 0.30 mg/kg) of sodium monofluoroacetate (1080) on the survival and productivity of sheep were evaluated to establish a better understanding of 1080 poisoning and identify more specific changes diagnostic of toxicosis. In survivors, clinical si... | 18,788,206 |
Clinical evaluation of the Admiral 1.35m2 hollow-fibre membrane oxygenator. | This prospective study was designed to evaluate the fundamental clinical performance of a new, small surface area oxygenator. Data were collected from twenty patients undergoing first-time coronary artery bypass grafting using this device. This study focuses on how the reduction of surface area and prime volume affects... | 18,788,215 |
A clinical evaluation of the Dideco Kids D100 neonatal oxygenator. | In August 2006, Duke University Perfusion Services had the opportunity to be the first institution in the United States to clinically evaluate the Dideco D100 Neonatal Oxygenator. The device was used on six pediatric patients to facilitate correction or palliation of their cardiac defects, which included two arterial s... | 18,788,216 |
Direct effects of volatile anesthetics on cardiac function. | The volatile anesthetics are a class of general anesthetic drugs used by the perfusionist during cardiopulmonary bypass (CPB). These agents are used in low doses in combination with other anesthetics to produce complete anesthesia. During CPB, these agents are capable of safely anesthetizing the paitent. It is well und... | 18,788,217 |
Reduction of blood coagulation and monocyte-platelet interaction following the use of a minimal extracorporeal circulation system (Synergy) in coronary artery bypass grafting (CABG). | Cardiovascular surgery with cardiopulmonary bypass (CPB) induces activation of blood coagulation and systemic inflammation involved in post-operative complications. Our study evaluated the impact of the minimal extracorporeal circulation (mini-CPB) system (Synergy, Sorin Group) on these functional aspects. Twenty patie... | 18,788,218 |
Evaluation of short and tall stature in children. | Children and adolescents whose heights and growth velocities deviate from the normal percentiles on standard growth charts present a special challenge to physicians. Height that is less than the 3rd percentile or greater than the 97th percentile is deemed short or tall stature, respectively. A growth velocity outside t... | 18,788,236 |
Genital mycoplasma infections among women in an urban community of northern Nigeria: do we need to search for them? | To determine the incidence of genital Mycoplasma infection among females in Jos. High vaginal swab (HVS) and or Endocervical swab (ECS) samples were obtained from 476 females undergoing vaginal examinations along with other females who volunteered to enroll in the study Samples were processed using standard laboratory ... | 18,788,259 |
Hepatitis B vaccination status and needle stick injuries among medical students in a Nigerian university. | Hepatits B virus (HBV) is the most common blood borne pathogen that poses an occupational risk to Health-care workers. The incidence of infection following needle stick injury has been reported to be high among medical students. Effective vaccines against HBV are available. The aim of this study was to determine the va... | 18,788,262 |
Radiation protection practices of staff during extra-corporeal shock wave lithotripsy at Okada, Nigeria. | The study was designed to find out the radiation protection practices of radiologists and other staff involved in the first extra-corporeal shock wave lithotripsy in Nigeria, performed at Igbinedion Hospital and Medical Research Centre, Okada. Some members of staff who were present when the extra-corporeal shock wave l... | 18,788,264 |
[Research and application of computer-aided technology in restoration of maxillary defect]. | This paper presents a new method of designing restoration model of maxillectomy defect through Computer aided technology. Firstly, 3D maxillectomy triangle mesh model is constructed from Helical CT data. Secondly, the triangle mesh model is transformed into initial computer-aided design (CAD) model of maxillectomy thro... | 18,788,275 |
[Brain MRI image segmentation based on active contour model using electrostatic field method]. | A modified Snake algorithm for medical image segmentation based on improved Greedy method and electrostatic field model is presented in this paper. Based on Greedy method, this algorithm features a new adjacent point selection strategy and the corresponding criteria, which can be used for searching the potential snake ... | 18,788,277 |
[Estimation of brain tissue's hemoglobin oxygen saturation (SO2) of rats by artificial neural network]. | A specifically designed fiber optical spectrum system was applied to measure the hemoglobin oxygen saturation (SO2) of living rat's brain tissue. Collections of in vivo visible absorption spectrum measured by the fiber optical spectrometer at different SO2 as well as their corresponding SO2 values measured by OXImeter ... | 18,788,308 |
[Current status of researches in the development of blood tissue engineering product]. | The term "blood substitutes" includes plasma substitutes and blood cell substitutes in the broad sense, but in its narrow sense, it means red blood cell (RBC) substitutes, platelet substitutes and white blood cell (WBC) substitutes. The RBC substitutes includes perfluorocarbon, hemoglobin-based and encapsuled substitut... | 18,788,321 |
[Volume regulated anion channel and ischemia/reperfusion injury of myocardium]. | It has been shown that a lot of diseases were related with the change or loss of Cl- channel functions. Among the Cl- channels, volume-regulated anion channel (VRAC) plays important roles in myocardial ischemia/reperfusion injury, cardiac arrhythmia and apoptosis; it may become a new target in the clinical treatment of... | 18,788,323 |
Sensitivity and specificity of depression questionnaires in a college-age sample. | The authors evaluated the sensitivity and specificity of the Beck Depression Inventory-II (BDI-II; A. T. Beck, R. A. Steer, & G. K. Brown, 1996) and Center for Epidemiological Studies-Depression Scale (CESD; L. S. Radloff, 1977) questionnaires for a college-student sample. Results indicate that the BDI-II and CES-D... | 18,788,328 |
Pilot study of manual sugarcane harvesting using biomechanical analysis. | In many countries, sugar cane harvesting is a very labor-intensive activity in which workers usually become fatigued after manually cutting the cane for a few hours. They need frequent pauses for rest, and they experience sustained injuries from excessive stress on the joints and muscles of the body. The cutting tool a... | 18,788,332 |
[Sternal resection and chest wall reconstruction for primitive neuroectodermal tumor of the sternum]. | Primitive neuroectodermal tumor of the sternum is rare. A 59-year-old woman referred to our department with anterior chest pain and a tumor in the sternum. The patient was diagnosed as primitive neuroectodermal tumor of the sternum by core biopsy of the lesion. She received 2 cycles of preoperative chemotherapy with vi... | 18,788,370 |
[Multiple calcifying fibrous pseudotumor of the pleura]. | A newly recognized distinctive fibrous soft tissue lesion called "calcifying fibrous pseudotumor" (CFPT) was recently described in the soft tissue of the extremities, trunk, scrotum, groin, neck, or axilla. But CFPT orgining from the pleura is rare. A 44-year-old woman was admitted to our hospital for an investigation ... | 18,788,375 |
[Successful management of ruptured aortic arch aneurysm infected with methicillin-resistant Staphylococcus aureus]. | A 64-year-old woman was admitted due to back pain and dyspnea. She was suffering from fever of unknown origin for a few weeks without aortic aneurysm by enhanced chest computed tomography (CT). Chest CT taken 1 month later revealed rupture of aortic arch aneurysm. Total arch replacement was performed with in situ graft... | 18,788,376 |
[Successful perioperative management with non-invasive positive pressure ventilation in muscular dystrophy with thymoma; report of a case]. | We report a case of muscular dystrophy with thymoma that was detected by chance at the examination of his fatal arrhythmia. He has hypercapnea and restrictive pulmonary disfunction, but non-invasive positive pressure ventilation (NPPV) had not been introduced. Thymo-thymectomy was performed through reversed L-shaped me... | 18,788,386 |
[Molecular pathogenesis of chronic kidney disease]. | High blood pressure, poor glycemic control, obesity, metabolic syndrome, dyslipidemia, smoking and older age are the risk factors for susceptibility to and initiation of CKD. In these conditions, systemic blood pressure can be transmitted to the glomerular capillary network because of impairment of autoregulationary me... | 18,788,393 |
[A study of surgical procedures for inverted papilloma in the nasal cavity and paranasal sinuses]. | Inverted papilloma, although benign, recurs frequently and may become malignant, making definitive initial resection extremely important. We evaluated surgical procedures for recurrence and sites, with special reference to management of the orbital plate of the ethmoid and lacrimal bones, in 24 patients (32 cases) with... | 18,788,423 |
[Clinical analysis of patients with tuberculosis admitted on an emergency cases]. | A retrospective study was made of 75 patients with tuberculosis and tuberculous pleurisy who received medical care in our hospital from 2002 through 2006. Of the 75 patients, 9 were admitted as tertiary emergency cases, and 12 patients were admitted by ambulance as secondary emergency cases. We studied the reason for t... | 18,788,430 |
[A case of severe pulmonary hypertension associated with COPD treated with epoprostenol]. | A rare case of chronic obstructive pulmonary disease (COPD) with severe pulmonary hypertension (PH) was found in a 68-year-old man. COPD was diagnosed in his 50s, from which time he received home oxygen therapy. In January 2007, he was admitted due to progression of dyspnea. On admission to our hospital, arterial blood... | 18,788,437 |
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