title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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Wolbachia: master manipulators of invertebrate biology. | Wolbachia are common intracellular bacteria that are found in arthropods and nematodes. These alphaproteobacteria endosymbionts are transmitted vertically through host eggs and alter host biology in diverse ways, including the induction of reproductive manipulations, such as feminization, parthenogenesis, male killing ... | 18,794,912 |
Harmonic interferometry in the visible and UV, based on second- and third-harmonic generation of a 25 ps mode-locked Nd:YAG laser. | A second-harmonic interferometer using 25 ps pluses is presented, achieving a sensitivity of 9x10(-10) m in measuring line-integrated dispersion between 1064 and 532 nm. Using the same laser source, a third-harmonic interferometer is demonstrated for the first time to our knowledge, achieving a sensitivity of 7x10(-9) ... | 18,794,934 |
A picosecond time-resolved vibrational circular dichroism spectrometer. | We present an experimental setup to detect transient vibrational circular dichroism signals. A femtosecond laser system is synchronized to a photoelastic modulator to produce alternating left- and right-handed circularly polarized mid-IR pulses at 1 kHz repetition rate. Transient changes in the circular dichroism of th... | 18,794,939 |
Laser-induced fluorescence imaging of subsurface tissue structures with a volume holographic spatial-spectral imaging system. | A three-dimensional imaging system incorporating multiplexed holographic gratings to visualize fluorescence tissue structures is presented. Holographic gratings formed in volume recording materials such as a phenanthrenquinone poly(methyl methacrylate) photopolymer have narrowband angular and spectral transmittance fil... | 18,794,943 |
Optical parametric generation of nearly transform-limited mid-infrared pulses in dispersion-engineered nonlinear waveguides. | Optical parametric generation in dispersion-engineered waveguides fabricated by proton exchange in periodically poled lithium niobate is numerically investigated as a means for producing widely tunable mid-infrared ultrashort pulses starting from low energy pump pulses at a 1.55 microm wavelength and with 100 fs durati... | 18,794,946 |
Miniaturized bending-free solitons by restoring symmetry in periodically biased photorefractives. | We consider optical propagation through a centrosymmetric photorefractive crystal with the externally applied bias voltage modulated along the optical propagation direction. We analytically prove that, if the modulation scale is smaller than the optical diffraction length, the resulting effective nonlinearity has an ev... | 18,794,947 |
Nanofabrication with controllable localization energy based on the interference modulation of surface plasmons. | A nanolithography technique based on the interference of surface plasmons (SPs) is proposed and demonstrated to modulate the localized exposure energy. The SP waves participating in interference are excited by two distinct structures, namely, the grating and the nanotaper. Constructive or destructive interference, whic... | 18,794,976 |
A wavelength-selective add-drop switch using silicon microring resonator with a submicron-comb electrostatic actuator. | Electrostatic comb-drive micro actuator with submicron comb fingers was connected to silicon microring resonator to consist a wavelength-selective add-drop switch at 1.5 microm wavelength with variable coupling mechanism. A 500 nm wide 260 nm thick 63.4 microm long silicon microring waveguide was suspended in air with ... | 18,794,978 |
Nonlinear absorption in CuPc-doped PMMA thin film in the femtosecond regime: experimental and theoretical studies. | The nonlinear absorption (NLA) properties of copper phthalocyanine (CuPc)-doped polymethylmethacrylate (PMMA) thin film in the femtosecond regime were investigated both experimentally and theoretically. The open-aperture (OA) Z-scan measurements of the film were carried out by femtosecond laser pulse. A transition from... | 18,794,992 |
Optical turbulence parameters characterized via optical measurements over a 2.33 km free-space laser path. | Optical turbulence research contributes to improved laser communications, adaptive optics, and long-range imaging systems. This paper presents experimental measurements of scintillation and focal spot displacement to obtain optical turbulence information along a near-horizontal 2.33 km free-space laser propagation path... | 18,795,001 |
Ocean color remote sensing: choosing the correct depth weighting function. | Values of reflectance and remote sensing reflectance are proportional to the ratio of sea water backscattering to absorption. However, in vertically non-homogeneous waters, this fraction needs to be depth weighted. The usual practice uses normalized vertical transmittance profiles as the weighting function. Recently, i... | 18,795,006 |
Feedback control of an atom laser. | We report the first real-time feedback control of an atom laser. The unique feature of metastable helium atoms, the production of ions in the atom laser outcoupling process, is exploited to actively control the spatial location inside the Bose-Einstein condensate where outcoupling occurs. Unlike alkali atom lasers, thi... | 18,795,009 |
Soft X-ray holographic grating beam splitter including a double frequency grating for interferometer pre-alignment. | Grating beam splitters have been fabricated for soft X-ray Mach- Zehnder interferometer using holographic interference lithography. The grating beam splitter consists of two gratings, one works at X-ray laser wavelength of 13.9 nm with the spatial frequency of 1000 lines/mm as the operation grating, the other works at ... | 18,795,013 |
Instabilities and solitons in systems with spatiotemporal dispersion. | A simple model based on the 1D nonlinear Schrödinger equation is studied, which contains both spatially and temporally dispersive terms. Parametric instabilities for plane waves are analyzed in detail, and solitary waves (both bright and dark) are found. The model presented here is able to describe the non-trivial unst... | 18,795,025 |
Adaptive dielectric liquid lens. | A tunable-focus liquid lens using dielectrophoretic effect is demonstrated. When a voltage is applied to a dielectric liquid droplet, the generated electric field inside the droplet is inhomogeneous. As a result, the liquid bears a dielectric force and its surface profile can be reshaped which causes the focal length t... | 18,795,032 |
3D shape measurement of the aspheric mirror by advanced phase measuring deflectometry. | An advanced Phase Measuring Deflectometry(PMD) is proposed to measure the three dimensional (3D) shape of the aspheric mirror. In the measurement process, a liquid crystal display(LCD)screen displaying sinusoidal fringe patterns and a camera observing the fringe patterns reflected via the tested mirror, are moved along... | 18,795,046 |
Thin film solar cell design based on photonic crystal and diffractive grating structures. | In this paper we present novel light trapping designs applied to multiple junction thin film solar cells. The new designs incorporate one dimensional photonic crystals as band pass filters that reflect short light wavelengths (400 - 867 nm) and transmit longer wavelengths(867 -1800 nm) at the interface between two adja... | 18,795,062 |
Cardiotrophin-1. Review. | Cardiotrophin-1 is newly discovered chemokin with a lot of functions. Aim of our work was to describe most important of them. systematically scan of available scientific resources. Cardiotrophin-1 stimulates the proliferation of cardiomyocytes. Cardiotrophin-1 expression and plasma values are elevated in individuals wi... | 18,795,069 |
Macleaya cordata extract and Sangrovit genotoxicity. Assessment in vivo. | Sanguinarine (SG) has been reported to form DNA adducts in vitro and increase the levels of DNA single strand breaks in the blood and bone marrow of mice treated intraperitoneally with SG. Recently, we showed no genotoxic effects of orally administrated 120 mg/kg feed Macleaya cordata extract (a mixture of sanguinarine... | 18,795,072 |
Potential diagnostic markers in nodular lesions of the thyroid gland: an immunohistochemical study. | The differential diagnosis of thyroid nodules in routine practice can be problemmatic for both pathologists and clinicians. Effective treatment requires a determination of the biological nature of the lesions. For this reason, ancilliary diagnostic markers along with histological examination of the nodules may be usefu... | 18,795,075 |
Evaluation of the new software program DegifXL4 in the determination of the glycaemic indices of foodstuffs. | There is no standardized protocol for measuring glycemic index (GI) that takes time-of-day effects into account. The software DegifXL2 and Medtronic-Minimed's CGMS and Solutions, makes the GI calculation at breakfast and dinner time possible. The aim of this study was to assess the enhanced data processing software (De... | 18,795,077 |
The value of dynamic contrast enhanced breast MRI in mammographically detected BI-RADS 5 microcalcifications. | To evaluate the role of dynamic contrast-enhanced magnetic resonance imaging (MRI) in the diagnosis of BI-RADS-5 type of microcalcifications of the breast, to compare the size of the microcalcification lesions using mammography (MG) and MRI, and to determine the value of MRI in surgery for microcalcifications. The stud... | 18,795,084 |
Implementation of contact definitions calculated by FEA to describe the healing process of basal implants. | Bone structure around basal implants shows a dual healing mode: direct contact areas manifest primary osteonal remodeling, in the void osteotomy-induced spaces, the repair begins with woven bone formation. This woven bone is later converted into osteonal bone. The purpose of this study was to develop a model to accurat... | 18,795,095 |
Mitochondrial and nuclear genes suggest that stony corals are monophyletic but most families of stony corals are not (Order Scleractinia, Class Anthozoa, Phylum Cnidaria). | Modern hard corals (Class Hexacorallia; Order Scleractinia) are widely studied because of their fundamental role in reef building and their superb fossil record extending back to the Triassic. Nevertheless, interpretations of their evolutionary relationships have been in flux for over a decade. Recent analyses undermin... | 18,795,098 |
Discovery of porcine microRNAs and profiling from skeletal muscle tissues during development. | MiRNAs (microRNAs) play critical roles in many important biological processes such as growth and development in mammals. In this study, we identified hundreds of porcine miRNA candidates through in silico prediction and analyzed their expression in developing skeletal muscle using microarray. Microarray screening using... | 18,795,099 |
TRK-A, HER-2/neu, and KIT Expression/Activation Profiles in Salivary Gland Carcinoma. | Salivary duct carcinomas (SDCs) and adenoid cystic carcinomas (ACCs) are the most aggressive and the most frequent carcinomas of the salivary glands, respectively. Little is known about them in terms of molecular/biochemical characterization and conventional treatments are ineffective. On cryopreserved material, we ana... | 18,795,122 |
Proteasome Inhibitor MG132 Induces Apoptosis and Inhibits Invasion of Human Malignant Pleural Mesothelioma Cells. | Malignant pleural mesothelioma (MPM) is an aggressive malignancy tightly associated with asbestos exposure. The increasing incidence of MPM and its resistance to all therapeutic modalities necessitate an urgent development of new treatments for MPM. Proteasome inhibitors (PIs) have emerged as promising agents for treat... | 18,795,123 |
Circadian phase resetting via single and multiple control targets. | Circadian entrainment is necessary for rhythmic physiological functions to be appropriately timed over the 24-hour day. Disruption of circadian rhythms has been associated with sleep and neuro-behavioral impairments as well as cancer. To date, light is widely accepted to be the most powerful circadian synchronizer, mot... | 18,795,146 |
Shorter telomeres may mark early risk of dementia: preliminary analysis of 62 participants from the nurses' health study. | Dementia takes decades to develop, and effective prevention will likely require early intervention. Thus, it is critical to identify biomarkers of preclinical disease, allowing targeting of high-risk subjects for preventive efforts. Since telomeres shorten with age and oxidative stress, both of which are important cont... | 18,795,148 |
Right heart pressure increases after acute increases in ambient particulate concentration. | We explored the association between acute changes in daily mean pulmonary artery (PA) and right ventricular (RV) pressures and concentrations of ambient fine particulate matter [PM with aerodynamic diameter < or = 2.5 microm (PM(2.5))] as an explanation for previous associations between congestive heart failure (HF)... | 18,795,158 |
Raw single-wall carbon nanotubes induce oxidative stress and activate MAPKs, AP-1, NF-kappaB, and Akt in normal and malignant human mesothelial cells. | Single-wall carbon nanotubes (SWCNTs), with their unique physicochemical and mechanical properties, have many potential new applications in medicine and industry. There has been great concern subsequent to preliminary investigations of the toxicity, biopersistence, pathogenicity, and ability of SWCNTs to translocate to... | 18,795,165 |
Nicotine does not reduce blood flow to healthy bone in rats. | Given the increased incidence of orthopedic complications among smokers, we tested the null hypothesis that nicotine, the most vasoactive substance in cigarettes, does not reduce blood flow to long bones. Nicotine was administered to adult rats at a rate of 2.4 or 3.6 mg/kg/d for 2 weeks to determine if nicotine has a ... | 18,795,191 |
Scoring of dual fluorescein and ICG inflammatory angiographic signs for the grading of posterior segment inflammation (dual fluorescein and ICG angiographic scoring system for uveitis). | To propose a semiquantitative dual fluorescein angiography (FA) and indocyanine green angiography (ICGA) scoring system for uveitis that would assist in the follow-up of disease progression and monitoring response to treatment. The scoring system was based on the FA scoring systems, the standardized ICGA protocol, and ... | 18,795,232 |
Incidence of parathyroid glands located in thymus in patients with renal hyperparathyroidism. | Parathyroid glands are frequently located in thymus, and it is essential to resect thymic tissue from the neck incision, especially in surgery for renal hyperparathyroidism (HPT). In this study, we evaluated the incidence, location, and type of intrathymic parathyroid glands in 902 patients who underwent initial parath... | 18,795,242 |
Genetic variation in strains of zebrafish (Danio rerio) and the implications for ecotoxicology studies. | There is substantial evidence that genetic variation, at both the level of the individual and population, has a significant effect on behaviour, fitness and response to toxicants. Using DNA microsatellites, we examined the genetic variation in samples of several commonly used laboratory strains of zebrafish, Danio reri... | 18,795,247 |
Diagnosis and temporal evolution of signs of intracranial hypotension on MRI of the brain. | A comprehensive evaluation of cranial magnetic resonance imagings (MRIs) of 23 patients with intracranial hypotension (IH) was performed, and the evolution of the abnormalities on follow-up MRIs was correlated with the clinical outcome. The MRI report database at the University Health Network in Toronto was searched, a... | 18,795,275 |
Growth inhibition of Struvite crystals in the presence of juice of Citrus medica Linn. | Struvite, one of the components of urinary stone grows rapidly forming "staghorn-calculi", is a painful urological disorder. It is necessary to study the growth-inhibition of Struvite crystals. This in vitro study has been carried out in the presence of the juice of Citrus medica Linn. by using single diffusion gel gro... | 18,795,276 |
Subcutaneous panniculitis-like T-cell lymphoma in a child: whole-body MRI in the initial and follow-up evaluations. | Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) is classified as an unusual subtype of peripheral T-cell lymphoma that preferentially infiltrates the subcutaneous tissue without overt lymph node involvement. SPTCL is particularly rare in children, and there have been only a few case reports describing the US and... | 18,795,279 |
Effects of nitrogen sources on cell growth and lipid accumulation of green alga Neochloris oleoabundans. | Microalgal lipids are the oils of future for sustainable biodiesel production. However, relatively high production costs due to low lipid productivity have been one of the major obstacles impeding their commercial production. We studied the effects of nitrogen sources and their concentrations on cell growth and lipid a... | 18,795,284 |
Cardiac MRI and CT features of inheritable and congenital conditions associated with sudden cardiac death. | Cardiac MRI (CMR) and electrocardiogram (ECG)-gated multi-detector computed tomography (MDCT) are increasingly important tools in the identification and assessment of cardiac-related disease processes, including those associated with sudden cardiac death (SCD). While the commonest cause of SCD is coronary artery diseas... | 18,795,295 |
Diagnostic performance of contrast-enhanced ultrasound for complex cystic focal liver lesions: blinded reader study. | The study was aimed at evaluating the diagnostic performance of contrast-enhanced ultrasound (CEUS) in characterizing complex cystic focal liver lesions (FLLs). Sixty-seven complex cystic FLLs in 65 patients were examined with conventional ultrasound (US) and real-time CEUS. The US and CEUS images were reviewed by a re... | 18,795,298 |
Costs and effectiveness of a brief MRI examination of patients with acute knee injury. | The aim of this study was to assess the costs and effectiveness of selective short magnetic resonance imaging (MRI) in patients with acute knee injury. A model was developed to evaluate the selective use of MRI in patients with acute knee injury and no fracture on radiography based on the results of a trial in which 20... | 18,795,300 |
High-intensity focused ultrasound (HIFU): effective and safe therapy for hepatocellular carcinoma adjacent to major hepatic veins. | Hepatocellular carcinoma (HCC) is an especially frequent malignancy in China. Radiofrequency ablation, percutaneous ethanol injection, transarterial chemoembolization, cryoablation, microwave coagulation, and laser-induced interstitial thermotherapy all offer potential local tumor control and occasionally achieve long-... | 18,795,303 |
Complete decapitation of a motorcycle driver due to a roadblock chain. | An 18-year-old male driving an off-road motorcycle died from complete decapitation when his motorcycle tore a roadblock chain from its attachment. The decapitation injuries of the head and the torso corresponded perfectly, without apparent loss of tissue. The severance plane passed horizontally through the upper cervic... | 18,795,312 |
Rapid regression of retinal hemorrhage and neovascularization in a case of familial exudative vitreoretinopathy treated with intravitreal bevacizumab. | To report a case of familial exudative vitreoretinopathy (FEVR) rapidly resolved by intravitreal injection of bevacizumab. A 36-year-old woman complained about floaters and visual field defect. Funduscopic examinations revealed retinal vessel anastomosis located between the equator and ora serrata in both eyes. The rig... | 18,795,314 |
Electron microscopy of high pressure frozen samples: bridging the gap between cellular ultrastructure and atomic resolution. | Transmission electron microscopy has provided most of what is known about the ultrastructural organization of tissues, cells, and organelles. Due to tremendous advances in crystallography and magnetic resonance imaging, almost any protein can now be modeled at atomic resolution. To fully understand the workings of biol... | 18,795,316 |
Function and regulation of claudins in the thick ascending limb of Henle. | The thick ascending limb (TAL) of Henle mediates transcellular reabsorption of NaCl while generating a lumen-positive voltage that drives passive paracellular reabsorption of divalent cations. Disturbance of paracellular reabsorption leads to Ca(2+) and Mg(2+) wasting in patients with the rare inherited disorder of fam... | 18,795,318 |
The microscopic (optical and SEM) examination of putrefaction fluid deposits (PFD). Potential interest in forensic anthropology. | This article describes the potential interest in physical and forensic anthropology of the microscopic analysis of residues of putrefaction fluid, a calcified deposit frequently found associated with bone rests. Its sampling and analysis seem straightforward and relatively reproducible. Samples came from archeological ... | 18,795,323 |
Angiogenesis in salivary carcinomas with and without myoepithelial differentiation. | To investigate whether salivary carcinomas with and without myoepithelial differentiation could present differences regarding degree of angiogenesis, we compared tumor vascularization between adenoid cystic (31 cases) and epithelial-myoepithelial carcinomas (14) versus mucoepidermoid (37) carcinoma. The expression of p... | 18,795,324 |
Mediation of oviposition responses in the malaria mosquito Anopheles stephensi Liston by certain fatty acid esters. | The chemical factors involved in oviposition site selection by mosquitoes have become the focus of interest in recent years, and considerable attention is paid to the chemical cues influencing mosquito oviposition. Studies on synthetic oviposition attractants/repellents of long-chain fatty acid esters against Anopheles... | 18,795,330 |
Apparent autosomal dominant keratoconus in a large Australian pedigree accounted for by digenic inheritance of two novel loci. | Keratoconus is a debilitating ocular disease characterised by progressive asymmetrical thinning of the cornea, the clear covering at the front of the eye. The resulting protrusion of the cornea results in severe refractive error, in the most severe cases requiring corneal grafting. It is a complex disease with a geneti... | 18,795,334 |
Measurement of the concentration of three antituberculosis drugs in the focus of spinal tuberculosis. | This is an experimental study on the distribution of antituberculosis drugs such as rifampin, isoniazid, and pyrazinamide in pathologic vertebrae of spinal tuberculosis in order to provide the regimen of chemotherapy and surgical treatment of spinal tuberculosis. The distribution of antituberculosis drugs in pathologic... | 18,795,341 |
Relationship between psychological factors and performance-based and self-reported disability in chronic low back pain. | Cross sectional study, performed in an outpatient university based pain rehabilitation setting. To analyze the relationship between psychological factors (psychosocial distress, depression, self efficacy, self-esteem, fear of movement, pain cognitions and coping reactions) and performance-based and self-reported disabi... | 18,795,346 |
Spatial learning in pigs: effects of environmental enrichment and individual characteristics on behaviour and performance. | This study investigated the effects of both environmental enrichment and individual behavioural characteristics on spatial cognitive capabilities of pigs, using a novel latent spatial learning paradigm based on Tolman's detour experiments (1948). Pigs were housed either in 'barren' pens or in pens enriched with straw b... | 18,795,350 |
Modeling distraction osteogenesis: analysis of the distraction rate. | Distraction osteogenesis is a useful technique aimed at inducing bone formation in widespread clinical applications. One of the most important factors that conditions the success of bone regeneration is the distraction rate. Since the mechanical environment around the osteotomy site is one of the main factors that affe... | 18,795,353 |
Identification of Inonotus obliquus and analysis of antioxidation and antitumor activities of polysaccharides. | Inonotus obliquus, a wild wood-decay fungus which grows on Betula trees in cool climates, has a variety of biological activities that the scientific community is paying more and more attention to. However, the research work is moving at a snail's pace. The methods of strain identification and the hypha microstructure h... | 18,795,365 |
Laparoscopic rectosigmoid resection for acute sigmoid diverticulitis. | Laparoscopic sigmoid colectomy has been widely accepted as elective approach but is, however, still discussed controversially for acute cases. Patients receiving a laparoscopic early single-stage procedure benefit from an early postoperative convalescence with a minimum of disability. As more surgeons gain expertise in... | 18,795,376 |
Importance of routine preoperative upper GI endoscopy: why all patients should be evaluated? | Morbid obesity is associated with different gastrointestinal alterations and diseases. Surgically induced weight loss has become the best treatment for morbidly obese patients. Roux-en-Y gastric bypass is the most common procedure performed worldwide. Concerns regarding difficulties in further evaluation of stomach rem... | 18,795,381 |
Impact of a combined resistance and aerobic exercise program on motivational variables in breast cancer survivors: a randomized controlled trial. | Short term exercise interventions have been shown to be beneficial for breast cancer survivors soon after treatments but longer term adherence is needed. To examine the effects of a supervised exercise program on motivational variables in breast cancer survivors using Self-Determination Theory (SDT). Sixty breast cance... | 18,795,388 |
Wideband middle ear power measurement in infants and children. | Wideband middle ear power (WMEP) measurement is a method of middle ear analysis that may provide improved diagnostic capability over single-frequency tympanometry. However, normative data, information about test-retest reliability, and results in clinical disorders are needed for clinical application. Normative and rel... | 18,795,470 |
Tethered cord syndrome in adulthood. | The standard treatment for tethered cord syndrome (operative vs nonoperative management) that presents in adulthood remains controversial. A comparative study of tethered cord syndrome in adulthood is needed. A retrospective chart-based analysis. Patients admitted to Gulhane Military Medical Academy Department of Neuro... | 18,795,476 |
Spinal angiolipoma: case report and literature review. | Spinal angiolipoma (SAL) is an uncommon clinico-pathological entity. Single case report. Retrospective data analysis. An obese woman with a 1-year history of progressive spastic paraparesis and acute deterioration underwent magnetic resonance imaging of the thoracic spine, the results of which suggested a tumor compres... | 18,795,485 |
Putting medical nutrition on to the international agenda: actions by the European Nutrition for Health Alliance. | In the European Union, most attention from the public, policymakers and health promotion campaigns in relation to nutrition is aimed at obesity. Until recently, this has overshadowed another facet of poor nutrition, whereby inadequate nutritional intake--often associated with disease--leads to weight loss, impaired bod... | 18,795,500 |
Increased patient safety with an Internet-based reporting system. | An efficient, goal-directed and positive approach allows learning from medical errors. The systematic analysis of patient safety incidents increases initiative and innovation in problem solving. In Finland, a nationally implemented Internet-based, voluntary reporting system provides a tool for the development of patien... | 18,795,505 |
Survival of glass fiber post restorations over 5 years. | To evaluate the survival of glass fiber reinforced composite post (GFP) restorations and to identify risk factors for restoration failure. GFPs of three consecutively placed post systems, two tapered and one parallel-sided, were adhesively luted and the core was built with a resin composite. Teeth served as abutment te... | 18,795,525 |
Effect of intensive statin therapy on arterial elasticity in patients with coronary artery disease. | Reduced arterial compliance is an independent predictor of cardiovascular mortality and is commonly encountered in patients with coronary artery disease. Statins may produce cholesterol-independent effects which can result at least in part from direct improvement of the arterial function. In this study, we sought to de... | 18,795,584 |
Pregnancy and teratogenicity of antiepileptic drugs. | Maternal use of antiepileptic drugs (AEDs) during pregnancy has been associated with an increased risk of congenital abnormalities in the fetus. This is partly attributable to AEDs. We aimed to analyse seizure frequency and the rate and type of any congenital malformation related to pregnancies in women with epilepsy i... | 18,795,597 |
[Early recurrence after the resection of hepatocellular carcinoma]. | To observe the precise time of the recurrence after resection of hepatocellular carcinoma (HCC) and to further explore the risk factors associated with postoperative recurrence. Totally 94 patients who had undergone resection of HCC were divided into three groups based on the time of recurrence, which was indicated by ... | 18,795,612 |
[Laparoscopic anatomical hepatectomies for intrahepatic bile duct stone]. | To assess the feasibility and safety of laparoscopic anatomical hepatectomies (LAH) for intrahepatic bile duct stone. LAH was performed in 14 patients with intrahepatic bile duct stone, while another 20 patients with intrahepatic bile duct stone underwent classical operation. Surgical time, blood loss, postoperative co... | 18,795,622 |
The esthetic management of a severe isolated periodontal defect in the maxillary anterior. | A 30-plus year-old woman presented to the periodontist with a chief complaint concerning the esthetics of the black space between her maxillary right lateral and central incisors (Figure 1). The history of the problem dated back several years when her general dentist noted increased pocket depth in this area. The patie... | 18,795,645 |
High levels of serum basic fibroblast growth factor in children with biliary atresia. | The purpose of this study was to investigate the relationship between basic fibroblast growth factor (bFGF) and clinical outcome in biliary atresia (BA) patients after surgical treatment. Sixty-five pediatric patients with BA post Kasai operation and 12 healthy children were recruited. The patients were categorized int... | 18,795,654 |
Capecitabine cardiotoxicity--case reports and literature review. | This study presents 3 case reports of patients who experienced anginous pain during treatment with capecitabine. The interruption of capecitabine and sublingual or intravenous nitroglycerine treatment lead to recovery. Rechallenge of capecitabine with dose reduction of 30% lead to repeated anginous pain in 2 patients. ... | 18,795,667 |
Sexual function in men with rectal and rectosigmoid cancer after laparoscopic and open surgery. | Postoperative sexual dysfunction is a serious problem in rectal cancer patients. Although laparoscopic surgery for rectal cancer is reportedly feasible, there are few studies comparing male sexual function after laparoscopic and after open surgery. The aim of this study was to investigate and compare the incidences and... | 18,795,677 |
Optimizing time management after perforation by colonoscopy results in better outcome for the patients. | Perforation during colonoscopy is a rare but severe complication. The aim of this study was to assess the time management and laparoscopic therapy of this complication and to evaluate patient outcomes. A retrospective analysis was done on 15 patients operated for a perforation from colonoscopy between January 2000 and ... | 18,795,678 |
Deficient response of IL-6 impaired liver regeneration after hepatectomy in patients with viral hepatitis. | Liver regeneration after surgical resection is still a serious concern. The present study is designed to understand the relations between liver injury/regeneration and cytokines after hepatectomy with viral hepatitis. Twenty-one consecutive patients undergoing liver resection were studied, which included two patients w... | 18,795,707 |
Electrogastrography in patients with Roux-en-Y reconstruction after previous Billroth gastrectomy. | The aim of this prospective study was to characterize gastric myoelectrical activity in patients with Roux-en-Y reconstruction after previous Billroth gastrectomy. Thirteen patients entered the study (6 men and 7 women, aged 35-57). The mean time from Roux-en-Y reconstruction to electrogastrography (EGG) recording was ... | 18,795,720 |
Direct space decomposition of ELI-D: interplay of charge density and pair-volume function for different bonding situations. | The topological features, i.e., gradients and curvatures of the same-spin electron pair restricted electron localizability indicator (ELI-D) in position space are analyzed in terms of those of the electron density and the pair-volume function. The analysis of the topology of these constituent functions and their interp... | 18,795,765 |
Thermodynamics of unstable DNA structures from the kinetics of the microgene PCR. | The microgene polymerization reaction (MPR) generates head-to-tail tandem repeats from homoduplexes (HDs). In MPR initiation, one HD putatively aligns two others in the proximity required to form a nucleation complex, thus allowing the DNA polymerase to skip the intertemplate gap and generate an initial doublet (ID) pr... | 18,795,769 |
Conformation of adsorbed layers of polyNIPAM on silica in a binary solvent. | The conformation of poly( N-isopropylacrylamide) chains adsorbed at a silica interface was studied as a function of concentration in the methanol-water binary solvent mixture. Both water and methanol are good solvents for PNIPAM; however, in certain mixtures cononsolvency is induced by a lowering of the LCST. This led ... | 18,795,773 |
Intramolecular O-H...O hydrogen-bond-mediated reversal in the partitioning of conformationally restricted triplet 1,4-biradicals and amplification of diastereodifferentiation in their lifetimes. | The photoreactivity and nanosecond transient phenomena have been investigated for a rationally designed set of ketones 4-9 in order to gain comprehensive insights concerning the influence of intramolecular hydrogen bonding on (i) the lifetimes of triplet 1,4-biradicals and (ii) the partitioning of the latter between cy... | 18,795,778 |
Isolation, biological significance, synthesis, and cytotoxic evaluation of new natural parathiosteroids A-C and analogues from the soft coral Paragorgia sp. | Three unusual new steroid thioesters, parathiosteroids A-C (1a-3a), were isolated from the 2-propanol extract of the soft coral Paragorgia sp. collected in Madagascar. Their structures, determined by detailed spectroscopic analysis, were confirmed by synthesis and represent the first isolation of natural steroids beari... | 18,795,787 |
Macrocyclic cyclophanes with two and three alpha,omega-dichalcogena-1,4-diethynylaryl units: syntheses and structural properties. | By means of four- and six-component cyclization reaction various cyclophanes were synthesized. The components were the di(lithium) salts of 1,4-di(ethynyl)benzene (11), 4,4'-di(ethynyl)biphenyl (13), 1,4-di(ethynyl)-2,5-di(n-hexyl)benzene (18), and 1,4-di(ethynyl)-2,5-di(n-propyl)benzene (19). These building blocks wer... | 18,795,790 |
Kinetic and chemical mechanism of arylamine N-acetyltransferase from Mycobacterium tuberculosis. | Arylamine N-acetyltransferases (NATs) are cytosolic enzymes that catalyze the transfer of the acetyl group from acetyl coenzyme A (AcCoA) to the free amino group of arylamines and hydrazines. Previous studies have reported that overexpression of NAT from Mycobacterium smegmatis and Mycobacterium tuberculosis may be res... | 18,795,795 |
Preparation of CdS nanocrystals within supramolecular self-assembled nanoreactors and their phase transfer behavior. | A new strategy for the synthesis of CdS nanocrystals (NCs) within supramolecular self-assembly nanoreactors has been described. The self-assembly nanoreactors were readily constructed through the electrostatic interactions and ion pairs between palmitic acid and the terminal amine groups of hyperbranched polymer. In a ... | 18,795,808 |
Ferulic acid supplements abrogate oxidative impairments in liver and testis in the streptozotocin-diabetic rat. | The primary objective of this study was to assess the efficacy of ferulic acid (FA), a phenolic antioxidant, in ameliorating oxidative stress in the testis and liver of diabetic pubertal rats. Male (6 wk old) rats were rendered diabetic by an acute dose (60 mg/kg body weight, intraperitoneal) of streptozotocin (STZ) an... | 18,795,822 |
Owner-perceived, weighted quality-of-life assessments in dogs with spinal cord injuries. | To evaluate changes over time in owner-perceived, weighted quality-of-life assessments in dogs with spinal cord injuries and determine whether scores were associated with underlying etiology or with veterinarian-assigned scores for severity of neurologic dysfunction. Cohort study. 100 dogs with spinal cord injury. Dura... | 18,795,855 |
Comparison between coelioscopy and coeliotomy for liver biopsy in channel catfish. | To evaluate endoscopic liver biopsy and compare that technique with a standard coeliotomy biopsy technique in fish. Randomized controlled clinical trial. 30 channel catfish (Ictalurus punctatus). 10 fish were randomly assigned into control, coeliotomy, and coelioscopy groups. Anesthesia was performed with a recirculati... | 18,795,862 |
Nuclear transfer of sand cat cells into enucleated domestic cat oocytes is affected by cryopreservation of donor cells. | In the present study, we used the sand cat (Felis margarita) as a somatic cell donor to evaluate whether cryopreservation of donor cells alters viability and epigenetic events in donor cells and affects in vitro and in vivo developmental competence of derived embryos. In Experiment 1, flow cytometry analysis revealed t... | 18,795,868 |
A comparative analysis of standard microtiter plate reading versus imaging in cellular assays. | We evaluated the performance of two plate readers (the Beckman Coulter [Fullerton, CA] DTX and the PerkinElmer [Wellesley, MA] EnVision) and a plate imager (the General Electric [Fairfield, CT] IN Cell 1000 Analyzer) in a primary fluorescent cellular screen of 10,000 Molecular Libraries Screening Center Network library... | 18,795,873 |
Design of phenotypic screens for bioactive chemicals and identification of their targets by genetic and proteomic approaches. | Cell-based screening using phenotypic assays is a useful means of identifying bioactive chemicals for use as tools to elucidate complex cellular processes. However, the chemicals must display sufficient selectivity and their targets have to be identified. We describe how cell-based screening assays can be designed to m... | 18,795,880 |
Chemogenomics and cancer chemotherapy: cell-based assays to screen for small molecules that impair microtubule dynamics. | Microtubules are still a promising target for new therapeutic agents. Thus, there is a continuous interest for compounds able to modify microtubule assembly, either by interacting directly with tubulin, or by interacting with microtubules regulators. Because of its dynamic characteristics, the microtubule cytoskeleton ... | 18,795,881 |
COMMD1 expression is controlled by critical residues that determine XIAP binding. | COMMD {COMM [copper metabolism Murr1 (mouse U2af1-rs1 region 1)] domain-containing} proteins participate in several cellular processes, ranging from NF-kappaB (nuclear factor kappaB) regulation, copper homoeostasis, sodium transport and adaptation to hypoxia. The best-studied member of this family is COMMD1, but relati... | 18,795,889 |
Longitudinal monocyte human leukocyte antigen-DR expression is a prognostic marker in critically ill patients with decompensated liver cirrhosis. | Critical illness in cirrhotic patients is associated with a poor prognosis and increased susceptibility to infections. Monocyte HLA-DR expression is decreased in cirrhotic patients, but its prognostic value has not been investigated prospectively. Thirty-eight critically ill patients with decompensated liver cirrhosis ... | 18,795,898 |
The outcome in newborns with congenital diaphragmatic hernia in a Norwegian region. | To evaluate the therapeutic strategies used in neonates with congenital diaphragmatic hernia (CDH) during the last 15 years in our department. A retrospective study of 27 neonates with CDH treated at the Neonatal Intensive Care Unit at Ullevaal University Hospital between 1992 and 2006. Since 1992 we have used delayed ... | 18,795,908 |
Shave biopsy without local anaesthetic to diagnose basal cell carcinoma and other skin tumours prior to definitive treatment: analysis of 109 lesions. | Diagnostic biopsy of basal cell carcinoma and other skin tumours may be necessary prior to definitive treatment. To assess whether shave biopsy sampling of tumours without local anaesthetic can provide adequate tissue to make an accurate histological diagnosis, and to determine whether any discomfort is associated with... | 18,795,923 |
Methyldibromoglutaronitrile allergy: relationship between patch test and repeated open application test thresholds. | Methyldibromoglutaronitrile (MDBGN) is a preservative, which was approved for use in cosmetics in the mid-1980s. The incidence of allergy to MDBGN rose during the 1990s, but is now decreasing due to regulatory intervention. Experimental studies with other allergens have shown a significant relationship between the patc... | 18,795,931 |
Palifermin-induced flexural hyperpigmentation: a clinical and histological study of five cases. | Palifermin is a human keratinocyte growth factor that is efficacious in reducing duration and severity of oral mucositis during autologous haematopoietic stem-cell transplantation for haematological cancer as well as chemotherapy for colorectal cancers. We report the clinical and histological characteristics of a serie... | 18,795,935 |
The adaptive response of anaerobically grown Saccharomyces cerevisiae to hydrogen peroxide is mediated by the Yap1 and Skn7 transcription factors. | The molecular mechanisms involved in the ability of cells to adapt and respond to differing oxygen tensions are of great interest to the pharmaceutical, medical and fermentation industries. The transcriptional profiles reported in previous studies of cells grown under anaerobic, aerobic and dynamic growth conditions ha... | 18,795,957 |
Multimodal techniques for smoking cessation: a review of their efficacy and utilisation and clinical practice guidelines. | Nicotine addiction is a complex, chronic condition with physiological and psychological/behavioural aspects that make smoking cessation extremely difficult. This paper reviews current recommendations for smoking cessation and the efficacy of pharmacotherapy and behavioural modification techniques, used either alone or ... | 18,795,968 |
Obstructive sleep apnoea-hypopnoea syndrome presenting in the neurology clinic: a prospective 5-year study. | An observational study of cases of obstructive sleep apnoea-hypopnoea syndrome (OSAHS), both suspected and established, presenting to general neurology outpatient clinics over a 5-year period was undertaken. Only eight new cases of OSAHS, confirmed by sleep studies, were identified, most with neurological problems (poo... | 18,795,971 |
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