title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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Intrinsic severity as a determinant of antiepileptic drug refractoriness. | For the most part, resistance to medications in epilepsy is independent of the choice of antiepileptic drug. This simple clinical observation constrains the possible biological mechanisms for drug refractory epilepsy by imposing a requirement to explain resistance for a diverse set of chemical structures that act on an... | 18,852,835 |
The Severely-Distressed African American Family in the Crack Era: Empowerment is not Enough. | Numerous African American families have struggled for generations with persistent poverty, especially in the inner city. These conditions were further strained during the 1980s and 1990s by the widespread use of crack cocaine. For many, crack use became an obsession, dominated their lives, and superseded family respons... | 18,852,841 |
An integrated approach for the analysis of biological pathways using mixed models. | Gene class, ontology, or pathway testing analysis has become increasingly popular in microarray data analysis. Such approaches allow the integration of gene annotation databases, such as Gene Ontology and KEGG Pathway, to formally test for subtle but coordinated changes at a system level. Higher power in gene class tes... | 18,852,846 |
Evaluating assay precision. | * When evaluating the precision of a method it is necessary to assess the repeatability (within-run) and the total or within-laboratory precision. * It is insufficient to assess repeatability in a single run. * Clinical and Laboratory Standards Institute (CLSI) document EP05-A2 describes the protocols for determining t... | 18,852,851 |
A new antigen retrieval technique for human brain tissue. | Immunohistochemical staining of tissues is a powerful tool used to delineate the presence or absence of an antigen. During the last 30 years, antigen visualization in human brain tissue has been significantly limited by the masking effect of fixatives. In the present study, we have used a new method for antigen retriev... | 18,852,880 |
Underutilization of social insurance among the poor: evidence from the Philippines. | Many developing countries promote social health insurance as a means to eliminate unmet health needs. However, this strategy may be ineffective if there are barriers to fully utilizing insurance. We analyzed the utilization of social health insurance in 30 hospital districts in the central regions of the Philippines be... | 18,852,881 |
Worm grunting, fiddling, and charming--humans unknowingly mimic a predator to harvest bait. | For generations many families in and around Florida's Apalachicola National Forest have supported themselves by collecting the large endemic earthworms (Diplocardia mississippiensis). This is accomplished by vibrating a wooden stake driven into the soil, a practice called "worm grunting". In response to the vibrations,... | 18,852,902 |
Fibromyalgia syndrome: definition and diagnostic aspects. | Ever since it was first defined, fibromyalgia (FM) has been considered one of the most controversial diagnoses in the field of rheumatology, to the point that not everybody accepts its existence as an independent entity. The sensitivity and specificity of the proposed diagnostic criteria are still debated by various sp... | 18,852,904 |
Model-based assessment of data availability in health information systems. | To introduce a formal definition of data availability as a contribution to trustworthiness of health information systems and to automatically detect respective weaknesses and propose solutions. Specifying an ontology, based on enterprise functions and application systems of (health) information systems and closely link... | 18,852,915 |
Thyroid sonomorphology, thyroid peroxidase antibodies and thyroid function: new epidemiological data in unselected German employees. | Employees of Sanofi-Aventis Deutschland GmbH underwent thyroid screening in 2006 to assess new data about the prevalence of irregular sonomorphological pattern, elevated thyroid peroxidase antibodies (TPO AB) and thyroid function in an unselected adult German population. The examination included 700 unselected employee... | 18,852,925 |
Human papillomavirus infection in men residing in Brazil, Mexico, and the USA. | To assess Human Papillomavirus (HPV) type distribution among men ages 18 years and older recruited from three different countries utilizing a common protocol for sampling HPV detection, and to evaluate whether HPV detection differs by age and country. MATERIAL AD METHODS: The study protocol includes a pre-enrollment ru... | 18,852,938 |
[Endoscopic placement of a "plug" made of acellular biomaterial: a new technique for the repair of gastric leak after Roux-en-Y gastric bypass]. | Roux-en-Y gastric bypass is one of the most commonly performed bariatric surgeries in Brazil. Gastric leaks are relatively uncommon and potentially dangerous complications. The initial management of gastric leaks consists in adequate drainage, nutritional support, antibiotics and acid suppression. In almost 30% of the ... | 18,852,948 |
The small bowel flora in individuals with cecoileal reflux. | The observation of cecoileal reflux to barium enema is not rare; however, its causes and consequences have not been widely investigated. Considering that ileocecal junction exerts a function as barrier to invasion of bacteria from colon to small bowel, it seems interesting to study the intestinal microflora in subjects... | 18,852,949 |
Detection of hepatitis B virus DNA in sera from 18 alcoholic carriers of "anti-HBc alone" and response to a single dose of hepatitis B vaccine. | To evaluate the possibility of occult hepatitis B virus (HBV) infection in alcoholics carriers of "anti-HBc alone", and to verify the behavior of this serological pattern after a single dose of hepatitis B vaccine, 18 alcoholics who had this serological profile were evaluated by the polymerase chain reaction method, an... | 18,852,957 |
Liver transplantation for acute liver failure: a 5 years experience. | Fulminant hepatic failure carries a high morbidity and mortality. Liver transplantation has markedly improved the prognosis of patients with fulminant hepatic failure. To evaluate the outcome of 20 patients with acute liver failure and indication for liver transplantation. A retrospective review of 20 patients with acu... | 18,852,944 |
Actions in vocal health: a proposal for improving the vocal profile of teachers. | several authors have pointed to the urgent need of researches and actions involving teachers, in the school environment, that have a preventive and vocal health promotion character with the purpose of improving work conditions. to analyze the vocal complaints, laryngeal symptoms, vocal habits and vocal profile of teach... | 18,852,965 |
Transient evoked otoacustic emissions and distortion product in school children. | Past five years of age, the main complaint of children who are hard of hearing is that they have difficulty in learning. Compare these results to suspected hearing loss, through triage with the exams of evoked otoacoustic emissions (EOAE) transients (TEOAE) and by distortion product (DPEOAE), using data from audiometri... | 18,852,974 |
[Strongyloides stercoralis hyperinfection: autopsy case report]. | Asymptomatic infection due to Strongyloides stercoralis may result in potentially fatal disease in immunodepressed patients. A case of Strongyloides stercoralis hyperinfection discovered at autopsy in a 55-year-old man who had been undergoing treatment for multiple myeloma is reported, emphasizing the clinical and path... | 18,853,018 |
[New selective indicator medium for detection of Aeromonas and Plesiomonas: UNISC agar]. | We evaluated a new selective indicator medium (UNISC Agar) for isolation of classical enteropathogens, Aeromonas spp and Plesiomonas shigelloides. The xylose fermentation capacity is indicated by a yellow color (fermenting agents) or blue (no fermenting agent). This, together with the oxidase test, establishes it as an... | 18,853,024 |
Epigastric pain relating to menses can be a symptom of bowel endometriosis. | Endometriosis is a common affliction that may affect the intestinal tract. The objective of this case report was to describe an unusual clinical presentation of this form of the disease. The patient was a 35-year-old woman with epigastric pain that only occurred during menstruation, who had a history of bladder endomet... | 18,853,038 |
What is the angiography error when defining myocardial ischemia during percutaneous coronary interventions? | The angiography has been used as a reference standard to define coronary artery disease (CAD), although its limitations are well-known. The significance of the myocardial fractional flow reserve (FFR) in the assessment of CAD is well established. The aim of this study was to evaluate the accuracy of angiography when de... | 18,853,058 |
Athlete's heart or hypertrophic cardiomyopathy? | Intensive endurance training is able to cause a distinct pattern of functional and structural changes of the cardiovascular system. In an unknown proportion of athletes a so called "athlete's heart" develops. There is an overlap between this type of physiologic cardiac hypertrophy and mild forms of hypertrophic cardiom... | 18,853,091 |
How to manage patients with need for antiplatelet therapy in the setting of (un-)planned surgery. | The growing incidence of cardiovascular diseases leads to an increase in patients who require treatment with antiplatelet drugs. About 5% of patients who underwent a percutaneous coronary intervention will have to undergo surgery within the first year. In these patients the problem evolves how to handle the antiplatele... | 18,853,094 |
Chemopreventive potential of Epoxy clerodane diterpene from Tinospora cordifolia against diethylnitrosamine-induced hepatocellular carcinoma. | Medicinal plants are a promising source for identification of lead molecules for cancer therapy. In our continuous search to discover bioactive compounds from natural products, we isolated (5R, 10R)-4R, 8R-dihydroxy-2S, 3R:15, 16-diepoxycleroda-13(16), 17, 12S:18,1S-dilactone (ECD), a diterpenoid from Tinospora cordifo... | 18,853,103 |
VZV retinal vasculitis without systemic infection: diagnosis and monitoring with quantitative Polymerase Chain Reaction. | To report a case of unilateral varicella zoster virus (VZV) retinal vasculitis aspect in an immunocompetent child without systemic infection. Clinically, no signs of retinal necrosis or frosted branch vasculitis were present. This is an observational case report. Quantitative PCR was performed on the aqueous humor (AH)... | 18,853,105 |
Comparison of peristaltic and Venturi pumps in bimanual microincisional cataract surgery. | Comparison of peristaltic and Venturi pumps in bimanual microincision phacoemulsification on the success of the cataract surgery by using sleeveless phaco tip. Bimanual microincision phacoemulsification was done in 49 eyes using a 1.4-mm temporal clear corneal incision. A peristaltic pump was used in 23 eyes, and a Ven... | 18,853,107 |
Effect of Jinguo Weikang Capsule on proto-oncogene expression of gastric mucosa in rats with gastric precancerous lesions. | To study the effect of Jinguo Weikang Capsule [see text] on the gene expression of H-ras, epidermal growth factor receptor (EGFR), P53 and C-myc of the gastric mucosa in rats with gastric precancerous lesions, and to investigate the action mechanism of JWC on gastric precancerous lesions. A rat model with paratypical p... | 18,853,119 |
Observation on the effect of Salvia miltiorrhiza injection in treating traumatic hyphema and the opportune time for its application. | To observe the effect of Salvia miltiorrhiza Injection (SMI) in treating traumatic hyphema (TH) and the opportune time for its application. A retrospective study was conducted in 174 patients with TH (all with a single eye wounded), of whom 92 patients were treated with dicynone and 82 with SMI, and their status of rec... | 18,853,121 |
QTL mapping for grain filling rate and yield-related traits in RILs of the Chinese winter wheat population Heshangmai x Yu8679. | A set of 142 winter wheat recombinant inbred lines (RILs) deriving from the cross Heshangmai x Yu8679 were tried in four ecological environments during the seasons 2006 and 2007. Nine agronomic traits comprising mean grain filling rate (GFR(mean)), maximum grain filling rate (GFR(max)), grain filling duration (GFD), gr... | 18,853,131 |
Noninvasive ventilation for acute respiratory failure after lung resection: an observational study. | A single prospective randomized study found that, in selected patients with acute respiratory failure (ARF) following lung resection, noninvasive ventilation (NIV) decreases the need for endotracheal mechanical ventilation and improves clinical outcome. We prospectively evaluated early NIV use for ARF after lung resect... | 18,853,141 |
Reinfusion of unwashed salvaged blood after total knee arthroplasty in patients with rheumatoid arthritis. | Autotransfusion with unwashed salvaged blood (USB) is effective for avoiding allogeneic blood transfusion (ABT) in patients undergoing total knee arthroplasty (TKA). We performed a retrospective study to determine the percentage of patients receiving ABT and the volume of postoperative blood drainage after introduction... | 18,853,156 |
Cellular glutathione peroxidase in human brain: cellular distribution, and its potential role in the degradation of Lewy bodies in Parkinson's disease and dementia with Lewy bodies. | Glutathione peroxidase (GPx-1) is regarded as one of the mammalian cell's main antioxidant enzymes inactivating hydrogen peroxide and protecting against oxidative stress. Using control, Parkinson's disease (PD), and dementia with Lewy bodies tissue (DLB) we have shown that GPx-1 is a 21-kD protein under reducing condit... | 18,853,169 |
Typing keystroke duration changed after submaximal isometric finger exercises. | A repeated-measures laboratory experiment tested whether keystroke duration during touch-typing changes after a finger performs submaximal isometric flexion exercises. Fourteen right-handed touch-typists used right ring finger to perform three 15-min exercise conditions, two isometric exercises and a no-force condition... | 18,853,179 |
Field evaluation of G10, a celery (Apium graveolens)-based topical repellent, against mosquitoes (Diptera: Culicidae) in Chiang Mai province, northern Thailand. | The potential of G10, a celery (Apium graveolens)-based topical product, as a repellent against natural mosquito populations was evaluated in comparison to commercial (Insect Block 28) and standard (25% DEET) repellents in Chiang Mai province, northern Thailand. These repellent products afforded encouragingly excellent... | 18,853,188 |
Kinetic study of mannitol production using cashew apple juice as substrate. | The use of agriculture excess as substrate in industrial fermentations became an interesting alternative to reduce production costs and to reduce negative environmental impact caused by the disposal of these products. In this work, a kinetic study of mannitol production using cashew apple juice as substrate was studied... | 18,853,193 |
Studies on the activity and stability of immobilized horseradish peroxidase on poly(ethylene terephthalate) grafted acrylamide fiber. | Having been activated with glutaraldehyde, modified poly(ethylene terephthalate) grafted acrylamide fiber was used for the immobilization of horseradish peroxidase (HRP). Both the free HRP and the immobilized HRP were characterized by determining the activity profile as a function of pH, temperature, thermal stability,... | 18,853,194 |
Pilot-scale process development and scale up for antifungal production. | A pilot-scale fermentation was developed for an antifungal compound produced by a filamentous fungus. Replacement of galactose with lactose (20-fold cost savings) and a threefold phosphate reduction (15 to 5 g/L) improved productivity 2.5-fold. Addition of supplements--glycine, cobalt chloride, and trace elements--resu... | 18,853,195 |
Characterization of sulfate-reducing bacteria dominated surface communities during start-up of a down-flow fluidized bed reactor. | An anaerobic down-flow fluidized bed reactor was inoculated with granular sludge and started-up with sulfate containing synthetic wastewater to promote the formation of a biofilm enriched in sulfate-reducing bacteria (SRB), to produce biogenic sulfide. The start-up was done in two stages operating the reactor in batch ... | 18,853,208 |
Analysis of N-glycans in embryonated chicken egg chorioallantoic and amniotic cells responsible for binding and adaptation of human and avian influenza viruses. | The initial step essential in influenza virus infection is specific binding of viral hemagglutinin to host cell-surface glycan receptors. Influenza A virus specificity for the host is mediated by viral envelope hemagglutinin, that binds to receptors containing glycans with terminal sialic acids. Human viruses preferent... | 18,853,253 |
Inhibition of apoptosis by Heliothis virescens ascovirus (HvAV-3e): characterization of orf28 with structural similarity to inhibitor of apoptosis proteins. | Ascoviruses (AVs) induce a unique pathology in their insect host cells causing cleavage of the cells into virion-containing vesicles. The mechanism by which AVs induce vesicle formation is poorly understood. It is postulated that the virus initially induces apoptosis leading to cell fragmentation. The apoptotic bodies ... | 18,853,258 |
Estimation of chlorophyll-a concentration using field spectral data: a case study in inland Case-II waters, North China. | In the remote sensing of chlorophyll-a (Chla) in inland Case-II waters, the assumption that the optical parameter of Chla specific absorption coefficient a*ph remains constant usually restrains application of many models. In this paper, we presented a newly developed model [Rrs(-1)(lambda1) - Rrs(-1)(lambda2)] x Rrs(la... | 18,853,267 |
A novel transgenic mice model for venous malformation. | Vascular anomalies are most commonly seen in the head and neck region, and there is no animal model available of this disease until now. The purpose of this study was to construct a conditional murine polyomavirus middle T antigen gene (PyMT) transgenic mice model, in order to provide a basis for the treatment of vascu... | 18,853,270 |
Pupillometric assessment of autonomic nervous system in children with functional enuresis. | Functional enuresis is defined as repeated voiding of urine into bed or clothes in children after 5 years of age following the exclusion of major somatic diseases. Autonomic nervous system dysregulation has been proposed as a pathophysiologic mechanism in the etiopathogenesis. The objective of this study was to evaluat... | 18,853,271 |
Cloning of the Rhizomucor miehei 3-hydroxy-3-methylglutaryl-coenzyme A reductase gene and its heterologous expression in Mucor circinelloides. | In this study, the gene hmgR encoding the 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase) was cloned and characterized in the zygomycete fungus Rhizomucor miehei. The hmgR gene comprises a total of 3,585 bp including the coding sequence of a 1,058 amino acids length putative protein and five introns... | 18,853,273 |
A joint coordinate system proposal for the study of the trapeziometacarpal joint kinematics. | The International Society of Biomechanics (ISB) has recommended a standardisation for the motion reporting of almost all human joints. This study proposes an adaptation for the trapeziometacarpal joint. The definition of the segment coordinate system of both trapezium and first metacarpal is based on functional anatomy... | 18,853,290 |
Prediction of atmospheric degradation data for POPs by gene expression programming. | Quantitative structure-activity relationship models for the prediction of the mean and the maximum atmospheric degradation half-life values of persistent organic pollutants were developed based on the linear heuristic method (HM) and non-linear gene expression programming (GEP). Molecular descriptors, calculated from t... | 18,853,297 |
Postoperative lomefloxacin 0.3% prophylaxis in strabismus surgery. | To evaluate the efficacy of topical lomefloxacin 0.3% versus chloramphenicol 0.2% with polymyxin B 2500 U/ml in the treatment of patients after strabismus surgery. Seventy-nine consecutive patients who underwent strabismus surgery from April through October 2006 were randomized to receive topical lomefloxacin 0.3% (n =... | 18,853,315 |
Relationship between body mass index and brain volume in healthy adults. | There is a growing evidence that elevated body mass index (BMI) is associated with adverse neurocognitive outcome, though no study has examined whether morphometric differences are found in persons across the adult life span. We compared 201 healthy individuals in normal weight, overweight, and obese groups (aged 17-79... | 18,853,335 |
Targeting NF-kappaB: a promising molecular therapy in inflammatory arthritis. | The nuclear factor-kappa B family of transcription factors is intimately involved in the regulation of the inflammatory responses that play a fundamental role in the damage of articular tissues. Thus, many studies have examined the important contributions of components of the NF-kappaB signaling pathways to the pathoge... | 18,853,343 |
Mass spectrometry for the characterization of unsulfated chondroitin oligosaccharides from 2-mers to 16-mers. Comparison with hyaluronic acid oligomers. | This study reports for the first time the complete liquid chromatography/electrospray ionization mass spectrometry (LC/ESI-MS) and tandem mass spectrometry (MS/MS) analyses performed in negative ion mode of saturated unsulfated chondroitin oligosaccharides up to 16-mers and comparison with hyaluronic acid (HA) oligomer... | 18,853,395 |
Mandibular osteotomies for access to select parapharyngeal space neoplasms. | Tumors involving the parapharyngeal space present a challenge of surgical access. We reviewed all parapharyngeal space tumors resected at the University of California, San Francisco, between 2003 and 2006 and identified 14 patients who had a mandibular osteotomy to enhance surgical access to the parapharyngeal space. T... | 18,853,448 |
Angiosarcoma developing after curative induction chemotherapy and radiotherapy for locally advanced squamous cell carcinoma of the larynx. | Angiosarcoma arising after radiation is described in breast cancer but occurs elsewhere. Here, we present an angiosarcoma of the neck occurring after curative chemoradiation. This is a case of angiosarcoma developing 5 years after curative therapy for T3N0 squamous cell carcinoma of the supraglottic larynx. Therapy con... | 18,853,452 |
Incidence and risk factors of bisphosphonate-associated osteonecrosis of the jaws. | Intravenous bisphosphonate therapy has been used for treatment of benign and malignant bone diseases and has been linked to osteonecrosis of the jaws. Records of 638 patients treated with intravenous bisphosphonates were reviewed. Drug used, number of infusions, dosing interval, dosage, duration, and occasion of osteon... | 18,853,454 |
Structural characterization of in vitro rat liver microsomal metabolites of antihistamine desloratadine using LTQ-Orbitrap hybrid mass spectrometer in combination with online hydrogen/deuterium exchange HR-LC/MS. | In vitro drug metabolism study is an integral part of drug discovery process. In this report, we have described the application of LTQ-Orbitrap hybrid mass spectrometer in conjunction with online hydrogen (H)/deuterium (D) exchange high resolution (HR)-LC/MS for structural characterization of in vitro rat liver microso... | 18,853,472 |
ESI+ MS/MS confirmation of canine ivermectin toxicity. | Ivermectin is a semisynthetic macrocyclic lactone anthelmintic of the avermectin family derived from Streptomyces fermentation products. Avermectins are used as antiparasitic agents in domestic animals; although considered relatively safe, one must consider animal species, breed, weight, and age in dosage determination... | 18,853,478 |
Pulmonary Mycobacterium tuberculosis (Beijing strain) infection in a stray dog. | Mycobacterium tuberculosis infection in dogs is rarely reported and has not previously been documented in South Africa. A case of a stray Maltese crossbreed dog with extensive multifocal pulmonary tuberculosis due to M. tuberculosis is described. Pulmonary granulomas in this case were poorly encapsulated and contained ... | 18,853,521 |
Physician workforce: the special case of health centers and the National Health Service Corps. | Federally funded health centers and the National Health Service Corps (NHSC) depend on family physicians (FPs) and general practitioners (GPs) to meet the needs of millions of medically underserved people. Policy makers and workforce planners should consider how changes in the production of FPs would affect these progr... | 18,853,530 |
Observing object motion induces increased generalization and sensitivity. | Learning to recognize a new object requires binding together dissimilar images of that object into a common representation. Temporal proximity is a useful computational cue for learning invariant representations. We report experiments that demonstrate two distinct psychophysical effects of temporal association via obse... | 18,853,553 |
The monocular-boundary-contour mechanism in binocular surface representation and suppression. | Boundary contours are important for representing binocular surfaces, including those in binocular rivalry. Ooi and He (2006, Perception 35 581-603) showed that a half-image with a boundary contour defined by abutting gratings predominates in binocular rivalry. We investigated the monocular-boundary-contour mechanism us... | 18,853,556 |
Highlighting human form and motion information enhances the conspicuity of pedestrians at night. | Exploring how biological motion can make pedestrians more conspicuous to drivers at night, one-hundred-and-twenty participants were driven along an open-road route at night and pressed a button whenever they recognized that a pedestrian was present. A test pedestrian wearing black clothing alone or with 302 cm2 of retr... | 18,853,562 |
Non-invasive cardiac output measurement using a fast mixing box to measure carbon dioxide elimination. | This study investigated the accuracy of a new technique for measuring cardiac output using the derivative Fick principle based on the ratio of change in the partial pressures of end-tidal and mixed expired carbon dioxide produced by short periods of partial rebreathing. A prospective clinical study involving 24 patient... | 18,853,584 |
An audit of perioperative cardiac arrests in a Southeast Asian university teaching hospital over 15 years. | An audit of the incidence, causes and outcome of perioperative cardiac arrest was conducted in a university hospital in Pakistan. All perioperative cardiac arrests from induction of anaesthesia to post anaesthesia care unit discharge or intensive care unit admission during noncardiac surgery, from January 1992 to Decem... | 18,853,592 |
Anemia, interleukin-10, tumor necrosis factor alpha, and erythropoietin levels in children with acute, complicated and uncomplicated malignant malaria in Jazan, Saudi Arabia. | To gain insight into potential relationships between tumor necrosis factor alpha (TNF-alpha), interleukin 10 (IL-10), erythropoietin (EPO), and anemia in acute malaria, 90 children 3 to 11 years with acute malaria were studied. According to parasitemia and hemoglobin levels, they were divided into 3 groups: G1 (mild): ... | 18,853,611 |
Detection of molecular markers of toxoplasmosis among Egyptian patients with miscarriage using avidity IgG-ELISA and Western blotting. | A total of 54 miscarriage patients were divided into 3 groups. GI: 10 toxoplasmosis patients with +ve IgM-ELISA; GII: 24 toxoplasmosis patients with +ve IgG-ELISA, and GIII: 20 non-toxoplasmosis cross-matched females as a control. All groups were subjected to IgG-avidity ELISA & IgG-avidity immunoblotting. Avidity ... | 18,853,626 |
Cystic hydatidosis: a zoonotic silent health problem. | Examination of five hundred pet dogs revealed Echinococcus granulosus in nine dogs, Dipylidium caninum in twenty dogs, and Toxocara canis in thirty dogs. The risky role played by pet dogs in the transmission and spreading of zoonotic cystic hydatidosis was discussed. | 18,853,634 |
Multilocus genetic analysis of Cryptosporidium isolates from Saudi Arabia. | A total of 35 Cryptosporidium positive samples were collected from children in Jeddah city. The samples were microscopically examined with Ziehl Neelsen (ZN) and Auramin phenol (AP) staining methods. Cryptosporidium antigen was detected in the faecal samples by using the Cryptosporidium ELISA kit. Cryptosporidium sp. w... | 18,853,635 |
Domestic violence, contraceptive use, and unwanted pregnancy in rural India. | This study examines the relationship between male-to-female physical domestic violence and unwanted pregnancy among women in three economically and culturally diverse areas of India. A central methodological focus of the study is the examination of retrospective and prospective measures of pregnancy unwantedness, contr... | 18,853,639 |
[Time dependent effect of melatonin administration on lipid peroxidation, superoxide dismutase activity and melatonin concentration in the elderly patients with essential arterial hypertension]. | Oxidative stress and melatonin (the pineal hormone) are involved in the pathogenesis of aging and aging-related diseases, including essential arterial hypertension. The aim of study was determination of time dependent effect of melatonin administration on malondialdehyde (MDA) concentration, Cu, Zn-superoxide dismutase... | 18,853,657 |
[Premedication with intraoperative clonidine and low-dose ketamine in outpatient laparoscopic cholecystectomy]. | To determine the efficacy of premedication with intraoperative clonidine in association with low-dose ketamine to reduce the need for postoperative opiate analgesia in outpatient laparoscopic cholecystectomy. We performed a prospective study of patients undergoing outpatient laparoscopic cholecystectomy between Novembe... | 18,853,679 |
Incidence of lymphocytic esophagitis in baboons. | We previously reported a novel histological phenotype of chronic esophagitis, lymphocytic esophagitis, in patients without gastroesophageal reflux. The aim of the present study was to explore the possible occurrence of lymphocytic esophagitis in baboons. Filed hematoxylin and eosin (H&E)-stained sections from the e... | 18,853,756 |
H-ras and c-fos exhibit similar expression patterns during most stages of oral oncogenesis. | H-ras and c-fos oncogenes interact in signalling pathways but their level and time course of expression during oral cancer development are unclear. The present study used an animal model for the simultaneous investigation of H-Ras and c-Fos expression in sequential stages of oral oncogenesis. Three experimental groups ... | 18,853,758 |
Clay minerals affect the stability of surfactant-facilitated carbon nanotube suspensions. | Carbon nanotubes (CNTs), because of their wide application, will inevitably enter aquatic systems, but the fate and transport of their suspensions in the environment are largely unknown. Clay minerals are expected to interact with CNT suspensions, affecting their fate and bioavailability. This study investigated the in... | 18,853,802 |
Whole body diffusion weighted imaging: a new era of oncological radiology. | Cancer has become the leading cause of mortality in the urban area of China. Whole body diffusion weighted imaging (WB-DWI), also known as virtual positron emission tomography, has gradually become accepted as an image tool in tumor localization, characterization, staging and monitoring response to therapy or tumor rec... | 18,853,845 |
Experimental study of inflammatory and metastatic lymph nodes with diffusion weighted imaging on animal model: comparison with conventional methods. | To investigate the feasibility of magnetic resonance (MR) diffusion weighted imaging (DWI) in discriminating inflammatory from VX2 carcinoma metastatic lymph nodes in rabbit model. Twenty New Zealand white rabbits were randomly divided into 2 groups. Complete Freund's adjuvant was injected into the bilateral dorsal foo... | 18,853,852 |
Neurogenic inflammation of the upper airway mucosa. | Chronic inflammation of the upper airway mucosa is most likely caused by multiple factors, but is frequently associated with local neurogenic inflammation. This phenomenon can be induced by the inhalation of exogenous particles and chemicals present in our environment, as well as irritants produced endogenously. These ... | 18,853,864 |
The relationship between allergy and rhinosinusitis. | IgE-mediated hypersensitivity is considered by some to be a predisposing factor for developing rhinosinusitis, although the theory is still controversial. The purpose of this study was to evaluate the relationship between allergy and rhinosinusitis. A cross-sectional study. 198 rhinitis patients were enrolled. An aller... | 18,853,872 |
Tissue-specific immunoglobulin E in maxillary sinus mucosa of allergic fungal sinusitis. | The objectives of this prospective study were to analyze the specific immunoglobulin E (sIgE) in maxillary sinus mucosa and to determine the importance of local tissue sIgE in the patients with allergic fungal sinusitis (AFS). We investigated tissue-specific IgE in the maxillary sinus mucosa. Thirty-four patients with ... | 18,853,876 |
A feasibility study of methodology for recruitment and for comparative testing of ciliary function in Hawaiians and Caucasians. | Native Hawaiians have higher lung cancer incidence and mortality than other ethnic groups, even after controlling for smoking. Could reduced mucociliary clearance, suspected in Polynesians, play a role? In this pilot study of 9 Hawaiian and 8 Caucasian men, mean velocities were faster although not statistically signifi... | 18,853,892 |
Zolpidem extended-release 12.5 mg associated with improvements in work performance in a 6-month randomized, placebo-controlled trial. | Although most research on pharmacotherapy for chronic insomnia focuses on changes in sleep outcomes, the functional impact of treatment is also of great importance to patients, families, physicians, and employers. To analyze changes in functioning at work (or work performance) among a subset of employed subjects (N = 7... | 18,853,934 |
Lack of effects of pramipexole on REM sleep behavior disorder in Parkinson disease. | REM sleep behavior disorder (RBD) is a common manifestation of Parkinson disease (PD) which is characterized by dream-enacting behaviors, unpleasant dreams, and loss of muscle atonia during REM sleep. Dopaminergic mechanisms are thought to play a role in RBD pathogenesis. To further asses such a role, we have evaluated... | 18,853,939 |
CD8+ T-Cell depletion and rapamycin synergize with combined coreceptor/stimulation blockade to induce robust limb allograft tolerance in mice. | The growing development of composite tissue allografts (CTA) highlights the need for tolerance induction protocols. Herein, we developed a mouse model of heterotopic limb allograft in a stringent strain combination in which potentially tolerogenic strategies were tested taking advantage of donor stem cells in the graft... | 18,853,957 |
Iron intake and body iron stores as risk factors for Barrett's esophagus: a community-based study. | High iron stores are a proposed modifiable risk factor for esophageal adenocarcinoma, but minimal human data exist. We evaluated whether iron intake and iron stores were associated with Barrett's esophagus, a metaplastic change that is a strong risk factor for esophageal adenocarcinoma. We conducted a case-control stud... | 18,853,987 |
Molecular mechanisms of pancreatitis: current opinion. | Pancreatitis (necroinflammation of the pancreas) has both acute and chronic manifestations. Gallstones are the major cause of acute pancreatitis, whereas alcohol is associated with acute as well as chronic forms of the disease. Cases of true idiopathic pancreatitis are steadily diminishing as more genetic causes of the... | 18,853,993 |
Transgenic rice expressing Allium sativum leaf agglutinin (ASAL) exhibits high-level resistance against major sap-sucking pests. | Rice (Oryza sativa) productivity is adversely impacted by numerous biotic and abiotic factors. An approximate 52% of the global production of rice is lost annually owing to the damage caused by biotic factors, of which approximately 21% is attributed to the attack of insect pests. In this paper we report the isolation,... | 18,854,007 |
The dual transcriptional regulator CysR in Corynebacterium glutamicum ATCC 13032 controls a subset of genes of the McbR regulon in response to the availability of sulphide acceptor molecules. | Regulation of sulphur metabolism in Corynebacterium glutamicum ATCC 13032 has been studied intensively in the last few years, due to its industrial as well as scientific importance. Previously, the gene cg0156 was shown to belong to the regulon of McbR, a global transcriptional repressor of sulphur metabolism in C. glu... | 18,854,009 |
A role for SNX5 in the regulation of macropinocytosis. | The mechanisms and components that regulate macropinocytosis are poorly understood. Here we have investigated the role of sorting nexin 5 (SNX5) in the regulation of macropinocytic activity. SNX5 is abundantly expressed in macrophages, cells very active in macropinocytosis, and is recruited onto newly-formed macropinos... | 18,854,019 |
Lifestyle counseling in hypertension-related visits--analysis of video-taped general practice visits. | The general practitioner (GP) can play an important role in promoting a healthy lifestyle, which is especially relevant in people with an elevated risk of cardiovascular diseases due to hypertension. Therefore, the aim of this study was to determine the frequency and content of lifestyle counseling about weight loss, n... | 18,854,020 |
Complete genome sequence of a highly divergent astrovirus isolated from a child with acute diarrhea. | Astroviruses infect a variety of mammals and birds and are causative agents of diarrhea in humans and other animal hosts. We have previously described the identification of several sequence fragments with limited sequence identity to known astroviruses in a stool specimen obtained from a child with acute diarrhea, sugg... | 18,854,035 |
Transcriptional regulation of subclass 5b fimbriae. | Enterotoxigenic Escherichia coli (ETEC) is a major cause of infant and child mortality in developing countries. This enteric pathogen causes profuse watery diarrhea by elaborating one or more enterotoxins that intoxicate eukaryotic cells and ultimately leads to a loss of water to the intestinal lumen. Virulence is also... | 18,854,044 |
Sickness behaviour pushed too far--the basis of the syndrome seen in severe protozoal, bacterial and viral diseases and post-trauma. | Certain distinctive components of the severe systemic inflammatory syndrome are now well-recognized to be common to malaria, sepsis, viral infections, and post-trauma illness. While their connection with cytokines has been appreciated for some time, the constellation of changes that comprise the syndrome has simply bee... | 18,854,046 |
Tracheopathia chondro-osteoplastica--an unusual cause of stridor. | A case of tracheopathia chondro-osteoplastica causing sub-glottic stenosis is described. Case report and literature review. A 37-year-old man presented with a 15-year history of gradually worsening dyspnoea and stridor due to sub-glottic stenosis. His medical and radiographic records were reviewed. This patient's prese... | 18,854,058 |
Successful treatment of secondary hemophagocytic lymphohistiocytosis in a patient with disseminated histoplasmosis. | Hemophagocytic lymphohistiocytosis (HLH) is an overwhelming inflammatory response, associated with an outpouring of cytokines and inappropriate activation of the macrophage system, causing severe morbidity and possible death. HLH has inherited and acquired forms. Secondary HLH can be related to any number of underlying... | 18,854,090 |
Symposium: innovative techniques in human embryo viability assessment. Assessing embryo viability by measurement of amino acid turnover. | This review assesses the ability of non-invasive 'amino acid profiling' to predict early embryo viability. The history of amino acid supplementation of embryo culture media and the role of amino acids in early embryo development are first considered and these are followed by a review of methods to quantify amino acid d... | 18,854,101 |
Growth differentiation factor-9 and anti-Müllerian hormone expression in cultured human follicles from frozen-thawed ovarian tissue. | In-vitro growth of frozen-thawed human follicles is perceived as a potential option for restoring women's fertility. The aims of this study were: (i) to test the usefulness of a defined serum-free medium for growth of frozen-thawed human follicles; and (ii) to evaluate the expression of growth differentiation factor-9 ... | 18,854,109 |
The endoderm of the mouse embryo arises by dynamic widespread intercalation of embryonic and extraembryonic lineages. | The cell movements underlying the morphogenesis of the embryonic endoderm, the tissue that will give rise to the respiratory and digestive tracts, are complex and not well understood. Using live imaging combined with genetic labeling, we investigated the cell behaviors and fate of the visceral endoderm during gut endod... | 18,854,136 |
An Elmo-like protein associated with myosin II restricts spurious F-actin events to coordinate phagocytosis and chemotaxis. | Elmo proteins positively regulate actin polymerization during cell migration and phagocytosis through activation of the small G protein Rac. We identified an Elmo-like protein, ElmoA, in Dictyostelium discoideum that unexpectedly functions as a negative regulator of actin polymerization. Cells lacking ElmoA display an ... | 18,854,143 |
An Afg2/Spaf-related Cdc48-like AAA ATPase regulates the stability and activity of the C. elegans Aurora B kinase AIR-2. | The Aurora B kinase is the enzymatic core of the chromosomal passenger complex, which is a critical regulator of mitosis. To identify novel regulators of Aurora B, we performed a genome-wide screen for suppressors of a temperature-sensitive lethal allele of the C. elegans Aurora B kinase AIR-2. This screen uncovered a ... | 18,854,144 |
Global transcriptional repression in C. elegans germline precursors by regulated sequestration of TAF-4. | In C. elegans, four asymmetric divisions, beginning with the zygote (P0), generate transcriptionally repressed germline blastomeres (P1-P4) and somatic sisters that become transcriptionally active. The protein PIE-1 represses transcription in the later germline blastomeres but not in the earlier germline blastomeres P0... | 18,854,162 |
Sulforaphane induces DNA double strand breaks predominantly repaired by homologous recombination pathway in human cancer cells. | Cytotoxicity and DNA double strand breaks (DSBs) were studied in HeLa cells treated with sulforaphane (SFN), a well-known chemo-preventive agent. Cell survival was impaired by SFN in a concentration and treatment time-dependent manner. Both constant field gel electrophoresis (CFGE) and gamma-H2AX assay unambiguously in... | 18,854,174 |
Integrin alphavbeta3-mediated transcriptional regulation of TIMP-1 in a human ovarian cancer cell line. | We have previously reported that a disintegrin inhibits solid tumor growth and metastasis in mouse model [I.C. Kang, Y.D. Lee, D.S. Kim, A novel disintegrin salmosin inhibits tumor angiogenesis, Cancer Res. 59 (1999) 3754-3760; S.I. Kim, K.S. Kim, H.S. Kim, D.S. Kim, Y. Jang, K.H. Chung, Y.S. Park, Inhibitory effect of... | 18,854,176 |
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