title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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Health care M&A advisory alert: Delaware court decision illustrates importance of specialized due diligence on Medicare/Medicaid issues in health care acquisition. | Lawyers and clients contemplating a health care transaction must have a strong working knowledge not only of the applicable law, but also of the provider's needs and culture. As illustrated by a recent Delaware court decision, Interim Healthcare, Inc. et al. v. Spherion Corporation, parties engaging in health care prov... | 18,975,724 |
Prescription drug spending: contribution to health care spending and cost containment strategies. | Prescription drug costs have been the focus of much research in the health care economy, within managed care organizations, and hospital systems. Pharmacy costs are drivers of general health care spending, premium increases, and to a lesser extent, hospital spending. Factors contributing to increased prescription spend... | 18,975,728 |
[Nutrient contents in Kingdonia uniflora ramet and their relations to heterogeneous environment on Taibai Mountains]. | Taking the guerrilla type clonal plant Kingdonia uniflora at different altitudes in Taibai Mountain National Forest Park of Shaanxi Province, China as test material, the C, N, P, K and Mg contents in different vegetative organs of its ramet were measured. The results showed that ramet age, altitude, and their interacti... | 18,975,741 |
[Effects of compensation capacity and palatability on the dominance of plant species in grazing community]. | With simulated mowing experiment and field survey, the compensation capacity and dominance shift of nine alpine plant species in grazing community were studied. The results showed that for most test species, there existed definite correlations between their compensation capacity and palatability. The species with bette... | 18,975,742 |
[Impact of urbanization on vegetation phenology in major cities in Yangtze River Delta region]. | Based on the time series NDVI images from 1998 to 2005 and by the method of moving average, the vegetation phenology in urban areas and buffer zones of Shanghai, Hangzhou, Nanjing, Changzhou, Wuxi and Suzhou in Yangtze River Delta region were calculated. The difference of average phenology in urban areas and buffer zon... | 18,975,761 |
[The morphological alteration in myofiber fibrosis and expression in TGF-beta1 in long-term denervated posterior cricoarytenoid muscles]. | To investigate the morphological alteration and the protein expression of TGF-beta1 in long-term denervated posterior cricoarytenoid muscles (PCAMs) and to find the appropriate time point of reinnervation in long-term denervated PCAMs. Thirty-eight patients with vocal paralysis were recruited into four groups, the 6-12... | 18,975,778 |
[The expression and significance of NF-kappaB in the rat model of otitis media with effusion experimentally induced by ovalbumin]. | To investigate the T helper cells (Th) predominant differentiation and the modulation of nuclear transcription factors kappa B (NF-kappaB) in middle ear of rat model of otitis media with effusion (OME). Sixteen SD rats were randomly divided into OME (Exp group) and control group (Con group). The expression of NF-kappaB... | 18,975,780 |
[Study of electroreflectance spectrum and Franz-Keldysh effect at metal-GaAs interfaces]. | Electronic properties (electric field, Fermi level pinning and density of interface states) of Au-GaAs, Al-GaAs and Ni-GaAs interfaces were studied by optical methods. These interfaces were fabricated by depositing metals (Ni, Au and Al) on specialized surface-intrinsic-n+ (SIN+) GaAs samples. Electroreflectance (ER) w... | 18,975,783 |
[Studies of the g factor and optical spectra for CaZrO3:Mn4+ crystal]. | The complete high-order perturbation formula of g factor for 3d(3) ions in cubic octahedral site was derived. In the formula, both the contribution delta g(CF) to g-shift delta g (= g-g(s), where g(s) = 2.0023) due to crystal-field (CF) mechanism (related to the interactions of CF excited states with the ground state) ... | 18,975,784 |
[Measurement on gas temperature distribution by tunable diode laser absorption spectroscopy]. | The technique of tunable diode laser absorption spectroscopy (TDLAS) can be used for gas temperature distribution measurement by scanning multiple gas absorption lines with a tunable diode laser. The fundamental of gas temperature distribution measurement by TDLAS is introduced in the present paper, and the discretizat... | 18,975,785 |
[Method for measuring water content in fresh meat using diffusion reflectance near infrared spectroscopy and experiment]. | A method was established to determine water content of fresh meat in deep layer based on NIRS diffusion reflectance spectroscopy by using LEDs. The experimental apparatus was established to investigate internal water content with repeated experiments for pork and mince pork; the water concentration and the water conten... | 18,975,799 |
[Research on the background correction in the non-invasive sensing of glucose by near-infrared spectroscopy]. | For the non-invasive blood glucose concentration sensing by the near-infrared spectroscopy, the signal to noise ratio of the optical measurement system is very low. Both the content of glucose in body and the absorption coefficient of glucose in the near-infrared region are quite weak. More over, the structure of spect... | 18,975,800 |
[Study of discrimination of corn seed based on near-infrared spectra and artificial neural network model]. | A new non-destructive and rapid method was developed to discriminate varieties of corn seeds. The method is based on near-infrared reflectance spectroscopy (NIRS) and artificial neural network (ANN). The corn seeds used for this study involved four varieties: Gaoyou115, Nongda368, Nongda108 and Nongda4967. After collec... | 18,975,808 |
[Fast detection of sugar content in fruit vinegar using NIR spectroscopy]. | For the fast and exact detection of sugar content of fruit vinegar, near infrared (NIR) spectroscopy technique combined with least squares support vector machines (LS-SVM) algorithm was used to build the prediction model of sugar content in the present research. NIR spectroscopy is a nondestructive, fast and accurate t... | 18,975,809 |
[The estimation model of rice leaf area index using hyperspectral data based on support vector machine]. | In order to compare the prediction powers between the best statistical model and SVM technique using each VI for rice LAI, the VIs are as independent variables in statistical models and are as net inputs in SVM, and the rice LAI are as dependent variables in statistical models and are as net outputs in SVM. Hyperspectr... | 18,975,815 |
[Single particle measurement of suspended soil dust using laser desorption/ionization time-of-flight mass spectrometry]. | Real-time measurement of size and composition of single soil dust particles using an aerosol time-of-flight laser mas spectrometry (ATOFLMS) was designed in our lab. Each particle's aerodynamic diameter was determined by measuring the delay time between two continuous-wave lasers, a Nd:YAG laser with a 266 nm pulsed ou... | 18,975,833 |
[Analysis of trace elements and macro elements in 13 anti-anoxic traditional Tibetan medicine]. | Thirteen kinds of anti-anoxic Tibetan traditional medicine including Hongjingtianjiaonang, Anshensan, Wuweishiliusan, Zhangsongbaweichenxiangsan, Shiliuweidujuansan, Ershiwuweiyuganziwan, Ershiwuweizhuhuangjiaonang, Shiwuweilongdanwan, Mijueqingliangsan, Qishiweizhenzhuwan, Bawei-chenxiangsan, Liuweidingxiangsan and Qi... | 18,975,838 |
Reaction mechanism of HCN+ + C2H4: a theoretical study. | The complex doublet potential energy surface for the ion-molecule reaction of HCN(+) with C(2)H(4) is investigated at the B3LYP/6-311G(d,p) and CCSD(T)/6-311++G(3df,2pd) (single-point) levels. The initial association between HCN(+) and C(2)H(4) forms three energy-rich addition intermediates, 1 (HCNCH(2)CH(2)(+)), 2 (HC... | 18,975,875 |
How important are temperature effects for cluster polarizabilities? | State-of-the-art first-principle all-electron density functional theory calculations on small sodium clusters are performed to study the temperature dependency of their polarizabilities. For this purpose Born-Oppenheimer molecular dynamics simulations with more than 100,000 time steps (>200 ps) are recorded employin... | 18,975,878 |
Structure/property relationships for the thermotropic behavior of lysine-based amphiphiles: from hexagonal to smectic phases. | Amino acid-derived gemini surfactants arise as a potentially good alternative to the more conventional lipid and synthetic catanionic systems in view of their enhanced interfacial properties, increased chemical stability, and low toxicity. The presence of an amino acid as the polar headgroup allows toxicity reduction, ... | 18,975,881 |
Promiscuous sulfatase activity and thio-effects in a phosphodiesterase of the alkaline phosphatase superfamily. | The nucleotide phosphodiesterase/pyrophosphatase from Xanthomonas axonopodis (NPP) is a structural and evolutionary relative of alkaline phosphatase that preferentially hydrolyzes phosphate diesters. With the goal of understanding how these two enzymes with nearly identical Zn(2+) bimetallo sites achieve high selectivi... | 18,975,918 |
Rhodium-catalyzed silylation and intramolecular arylation of nitriles via the silicon-assisted cleavage of carbon-cyano bonds. | A rhodium-catalyzed silylation reaction of carbon-cyano bonds using disilane has been developed. Under these catalytic conditions, carbon-cyano bonds in aryl, alkenyl, allyl, and benzyl cyanides bearing a variety of functional groups can be silylated. The observation of an enamine side product in the silylation of benz... | 18,975,946 |
Cationic terminal gallylene complexes by halide abstraction: coordination chemistry of a valence isoelectronic analogue of CO and N2. | While N(2) and CO have played central roles in developing models of electronic structure, and their interactions with transition metals have been widely investigated, the valence isoelectronic diatomic molecules EX (E = group 13 element, X = group 17 element) have yet to be isolated under ambient conditions, either as ... | 18,975,947 |
Authentication of anglerfish species (Lophius spp) by means of polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and forensically informative nucleotide sequencing (FINS) methodologies. | Lophius represents the most important genus of the family Lophiidae from a commercial point of view. The main marketing formats of the species included in this genus are tails and cheeks, making impossible the species identification on the basis of their morphological characters. In the present study, two methods based... | 18,975,961 |
Fenhexamid adsorption behavior on soil amended with wine lees. | The adsorption of fenhexamid (FEN) [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide] on vineyard soil amended with wine lees (WL) produced by vinery was studied. The adsorption extent depends on WL fraction. The addition of the centrifuged solid lees (SWL) increases the FEN adsorption on soil. Most like... | 18,975,967 |
Differential RNA-dependent ATPase activities of four rRNA processing yeast DEAD-box proteins. | S. cerevisiae ribosome biogenesis is a highly ordered and dynamic process that involves over 100 accessory proteins, including 18 DExD/H-box proteins that act at discrete steps in the pathway. Although often termed RNA helicases, the biochemical functions of individual DExD/H-box proteins appear to vary considerably. F... | 18,975,973 |
Histopathologic and clinical features of medullary microcarcinoma and C-cell hyperplasia in prophylactic thyroidectomies for medullary carcinoma: a study of 42 cases. | Prophylactic thyroidectomies are increasingly performed on patients at risk for developing medullary thyroid carcinoma (MTC); consequently, pathologists are more commonly encountering these specimens in routine practice. To describe the detailed clinicopathologic features of prophylactic thyroidectomies for medullary c... | 18,976,013 |
Stability of tumor necrosis factor alpha, interleukin 6, and interleukin 8 in blood samples of patients with systemic immune activation. | Tumor necrosis factor alpha, interleukin 6, and interleukin 8 serum/plasma levels are frequently used for the monitoring of patients with systemic immune activation/ sepsis. This requires comparability of test results over time. However, cytokines are usually not considered to be very stable after blood collection, whi... | 18,976,019 |
Lipid profiles and prevalence of dyslipidemia in schoolchildren in south Khorasan Province, eastern Iran. | The aim of this study was to evaluate serum lipid profiles and the prevalence of dyslipidemia in schoolchildren in south Khorasan Province. The participants of this cross-sectional study were 685 girls and 641 boys, aged seven to 12 years, selected by multistage random cluster sampling from urban and rural areas of sou... | 18,976,028 |
Synchronous occurrence of small intestinal stromal tumor and cecal adenocarcinoma. | Synchronous development of gastrointestinal stromal tumors with other tumors in the digestive tract is relatively rare, and often occurs in the stomach. We report a 76-year-old woman, who suffered from the exceedingly rare synchronous development of small intestinal stromal tumor and cecal adenocarcinoma. The patient p... | 18,976,040 |
IL-23 and autoimmunity: new insights into the pathogenesis of inflammatory bowel disease. | The intestinal immune system has the challenge of maintaining both a state of tolerance toward intestinal antigens and the ability to combat pathogens. This balance is partially achieved by reciprocal regulation of proinflammatory, effector CD4(+) T cells and tolerizing, suppressive regulatory T cells. Inflammatory bow... | 18,976,050 |
Characterization of a side population of astrocytoma cells in response to temozolomide. | Cancer progenitor-like cells isolated by Hoechst 33342 dye efflux (termed the "side population" [SP]) have been studied in a variety of cancers, including malignant brain tumors. In this study, the authors investigate the nature of the SP phenotype in 2 glioma cell lines, U87MG and T98G, and their response to temozolom... | 18,976,075 |
Controlled release of heparin-binding growth factors using heparin-containing particulate systems for tissue regeneration. | The strategy of growth factor delivery to specific sites for therapeutic applications has been considered an essential process in biomedical fields despite some obstacles, such as a non-controlled release with initial burst. This article focuses on particulate systems using heparin for the controlled delivery of hepari... | 18,976,129 |
Drug delivery strategies for improved azole antifungal action. | Azole antifungal agents are the most commonly used antifungals in clinical treatment of both superficial and systemic fungal infections. Many azoles are poorly water soluble, which limits their bioavailability and antifungal effects. To improve the efficacy of azole antifungal drugs by advances in drug delivery. Manipu... | 18,976,131 |
Photosensitiser delivery for photodynamic therapy. Part 2: systemic carrier platforms. | The treatment of solid tumours and angiogenic ocular diseases by photodynamic therapy (PDT) requires the injection of a photosensitiser (PS) to destroy target cells through a combination of visible light irradiation and molecular oxygen. There is currently great interest in the development of efficient and specific car... | 18,976,134 |
Enhancing the nail permeability of topically applied drugs. | The topical therapy of nail diseases, especially of onychomycosis, and to a smaller extent, of nail psoriasis, is desirable to avoid the side effects associated with their systemic therapy, to increase patient compliance and reduce the cost of treatment. Systemic therapy is however the mainstay of treatment due to the ... | 18,976,136 |
Atomic-scale templates patterned by ultrahigh vacuum scanning tunneling microscopy on silicon. | The ultrahigh vacuum (UHV) scanning tunneling microscope (STM) enables patterning and characterization of the physical, chemical, and electronic properties of nanostructures on surfaces with atomic precision. On hydrogen-passivated Si(100) surfaces, selective nanopatterning with the STM probe allows the creation of ato... | 18,976,139 |
Cost-sharing: a blunt instrument. | Cost-sharing is a health care cost-containment technique in which health care services are partially paid for by patients out of pocket. Cost-sharing can reduce non-cost-effective care, but it can also undermine the financial protection and access values of health insurance. We review the empirical evidence published s... | 18,976,141 |
Postoperative intravenous patient-controlled analgesia in thyroid surgery: comparison of fentanyl and ondansetron regimens with and without the nonsteriodal anti-inflammatory drug ketorolac. | Nonsteroidal anti-inflammatory drugs (NSAIDs), through synergistic action with opioids, can reduce postoperative nausea and vomiting via intravenous patient-controlled analgesia (PCA). We compared the efficacy of three PCA regimens. Patients (n = 135) undergoing thyroidectomy were randomly allocated to three PCA regime... | 18,976,162 |
Vaccination and screening of medical students: results of a student health initiative. | To evaluate the immune status and vaccination needs of first-year medical students in relation to bloodborne viruses and common vaccine-preventable diseases. Survey of first-year medical students at the University of New South Wales, Sydney, NSW, attending a mandatory screening and vaccination clinic, 2002-2005. Self-r... | 18,976,187 |
The pathway to dementia diagnosis. | To describe the steps taken by health professionals to diagnose dementia and the timeframes for these steps, as reported by carers. A cross-sectional, anonymous survey was mailed or distributed by Alzheimer's Australia New South Wales, six Sydney residential aged care facilities and 13 Sydney general practitioners to 4... | 18,976,188 |
Effect of smoking among Indigenous and non-Indigenous mothers on preterm birth and full-term low birthweight. | To estimate the percentage of preterm (< 37 weeks) and full-term low-birthweight (37-41 weeks, < 2500 g) babies born to mothers who smoke, stratified by Indigenous status and statistically adjusted for the potential confounding effects of social and demographic factors, medical conditions and pregnancy complicati... | 18,976,189 |
The roles of socioeconomic status and Aboriginality in birth outcomes at an urban hospital. | To explore the role of socioeconomic status and Aboriginality on birthweight at an urban hospital. Extraction of data on the demographic characteristics (socioeconomic status, mothers' single-parent status, age and smoking status) and infants' birthweight from a clinical record system. Infants delivered at an outer urb... | 18,976,190 |
"All they said was my kidneys were dead": Indigenous Australian patients' understanding of their chronic kidney disease. | To explore the understanding of both Indigenous and non-Indigenous Australians with end-stage kidney disease (ESKD) about the cause of their disease, and how this understanding could affect patients' engagement with their treatment. Qualitative study conducted in 2005-2006 in nine hospital renal units and 17 associated... | 18,976,191 |
Social justice as a framework for undergraduate community health clinical experiences in the United States. | Educating future registered nurses for social justice is an urgent, yet complex undertaking in undergraduate education. Although the need for social justice education is often highlighted, few articles describe practical teaching strategies for ensuring that undertaking. The purpose of this article is to illustrate how... | 18,976,232 |
Improving communication among healthcare providers: preparing student nurses for practice. | Communication errors are identified by the Joint Commission as the primary root cause of sentinel events across all categories. In addition, improving the effectiveness of communication among healthcare providers is listed as one of the Joint Commission's 2008 National Patient Safety Goals. Nursing programs are expecte... | 18,976,237 |
Self-perceived oral health and salivary proteins in children with type 1 diabetes. | The aim was to validate self-perceived oral health with salivary IgG as an inflammatory parameter in children with type 1 diabetes. Unstimulated whole saliva samples were collected from 36 children with well controlled and 12 with poorly controlled type 1 diabetes and 40 non-diabetic children (Controls). Salivary flow ... | 18,976,260 |
Wear of human enamel and nano-filled composite resin denture teeth under different loading forces. | To evaluate and correlate the two-body wear of human enamel and nano-filled composite resin teeth with the loading forces used in a dual-axis chewing simulator. Three groups of human enamel and three of nano-filled composite resin teeth were tested in a chewing simulator. Zirconia ceramic balls were used as antagonists... | 18,976,262 |
Evaluation of different occlusal splints and counselling in the management of myofascial pain dysfunction. | The aim of this study was to compare the effectiveness of different occlusal splints associated with counselling and self-care in the management of signs and symptoms of myofascial pain. In a double-blind controlled clinical trial, 42 myofascial pain patients with chief complaint of pain in the masseter muscle area wer... | 18,976,268 |
Effect of turban use on temporomandibular joint problems. | The aim of this study was to evaluate the effects of daily turban wear on temporomandibular joint (TMJ) problems. This cross-sectional study was carried out on 249 female patients. Of these, 119 patients were using turban daily, while 130 patients did not use. Patients were asked questions to ascertain the signs of TMJ... | 18,976,273 |
Gestational diabetes mellitus in 13 dogs. | There are few reports on the clinical appearance, prognosis, and risk factors for gestational diabetes mellitus (GDM) in dogs. To describe the clinical characteristics of GDM in dogs. Thirteen dogs with GDM. Retrospective study. Medical records were reviewed and owners and referring veterinarians were contacted for fol... | 18,976,285 |
Nox-2 is a modulator of fibrogenesis in kidney allografts. | We studied the role of classical phagocytic NADPH oxidase (Nox) in the pathogenesis of kidney allograft tubulointerstitial fibrosis. Immunofluorescence studies showed that Nox-2 and p22phox (electron transfer subunits of Nox) colocalized in the tubulointerstitium of human kidney allografts. Tubular Nox-2 also colocaliz... | 18,976,289 |
Portal venous donor-specific transfusion in conjunction with sirolimus prolongs renal allograft survival in nonhuman primates. | Pretransplant exposure to donor antigen is known to modulate recipient alloimmunity, and frequently results in sensitization. However, donor-specific transfusion (DST) can have a protolerant effect that is dependent on route, dose and coadministered immunosuppression. Rodent studies have shown in some strain combinatio... | 18,976,300 |
Tongue weakness is associated with respiratory failure in patients with severe Guillain-Barré syndrome. | Swallowing impairment may worsen respiratory weakness and conduct to respiratory complications such as aspiration pneumonia in Guillain-Barré syndrome (GBS). We prospectively evaluate how tongue weakness could be associated to bulbar dysfunction and respiratory weakness in severe GBS patients. Tongue strength, dysphagi... | 18,976,323 |
Paramedic self-efficacy and skill retention in pediatric airway management. | The objectives were to determine the effect of pediatric airway management training on paramedic self-efficacy and skill performance and to determine which of several retraining methods is superior. A total of 2,520 paramedics were trained to proficiency in pediatric bag-mask ventilation (BMV) and endotracheal intubati... | 18,976,342 |
Alveolar ridge augmentation using implants coated with recombinant human bone morphogenetic protein-2: histologic observations. | Studies using ectopic rodent, orthotopic canine, and non-human primate models show that bone morphogenetic proteins (BMPs) coated onto titanium surfaces induce local bone formation. The objective of this study was to examine the ability of recombinant human BMP-2 (rhBMP-2) coated onto a titanium porous oxide implant su... | 18,976,397 |
The pathobiology of Kaposi's sarcoma: advances since the onset of the AIDS epidemic. | Since the perplexing early Kaposi's sarcoma (KS) observations at the dawn of the acquired immunodeficiency syndrome epidemic, KS has been extensively studied, revealing a complex disease. The identification and complete elucidation of the genome of its causal agent, the KS-associated herpesvirus/human herpesvirus 8, ha... | 18,976,418 |
Prospective study of physical activity and risk of postmenopausal breast cancer. | To prospectively examine the relation of total, vigorous and non-vigorous physical activity to postmenopausal breast cancer risk. We studied 32,269 women enrolled in the Breast Cancer Detection Demonstration Project Follow-up Study. Usual physical activity (including household, occupational and leisure activities) thro... | 18,976,449 |
Participation in everyday activities and quality of life in pre-teenage children living with cerebral palsy in South West Ireland. | Cerebral palsy (CP) is the most common cause of physical disability in children but its impact on quality of life is not well understood. This study examined participation in everyday activities among children without CP and children with mild, moderate and severe impairment due to CP. We then examined ten domains of q... | 18,976,459 |
Age differences at sexual debut and subsequent reproductive health: Is there a link? | Experiences at sexual debut may be linked to reproductive health later in life. Additionally, young women with older sexual partners may be at greater risk for HIV and sexually transmitted infections. This study examines sexual debut with an older partner and subsequent reproductive health outcomes among 599 sexually e... | 18,976,477 |
Promoter hypermethylation-mediated inactivation of LRRC4 in gliomas. | Leucine-rich repeat C4 protein (LRRC4) is a new member of the leucine-rich repeat (LRR) superfamily. It is not only a brain-specific gene but also a novel candidate for tumor suppression. LRRC4 inactivation is commonly found in glioma cell lines and primary glioma biopsies. However, little is known about the mechanism ... | 18,976,507 |
Health insurance of rural/township schoolchildren in Pinggu, Beijing: coverage rate, determinants, disparities, and sustainability. | As China re-establishes its health insurance system through various cooperative schemes, little is known about schoolchildren's health insurance. This paper reports findings from a study that examined schoolchildren's insurance coverage, disparities between farmer and non-farmer households, and effects of low-premium c... | 18,976,508 |
Activation of the JAK-STAT pathway is necessary for desensitization of 5-HT2A receptor-stimulated phospholipase C signalling by olanzapine, clozapine and MDL 100907. | We have previously demonstrated that olanzapine-induced desensitization of 5-HT2A receptor-stimulated phospholipase C (PLC) activity is associated with increases in RGS7 protein levels both in vivo and in cells in culture, and the increase in RGS7 is dependent on activation of the JAK-STAT pathway in cells in culture. ... | 18,976,543 |
Examining the geographical heterogeneity associated with risk of mistimed and unwanted pregnancy in Ghana. | After a decade of fertility decline, Ghana's fertility and the level of unmet need for contraception stalled in mid-transition in the late 1990s. Although the literature acknowledges this, the geographical patterns in unmet need have not been adequately documented. Spatial analysis of unmet need can reveal differences ... | 18,976,547 |
Successful treatment of disseminated Acanthamoeba sp. infection with miltefosine. | We report on an HIV-negative but immunocompromised patient with disseminated acanthamoebiasis, granulomatous, amoebic encephalitis and underlying miliary tuberculosis and tuberculous meningitis. The patient responded favorably to treatment with miltefosine, an alkylphosphocholine. The patient remained well with no sign... | 18,976,559 |
Role of human polyomaviruses in respiratory tract disease in young children. | KI virus was detected in respiratory secretions of 8/367 (2.2%) symptomatic and 0/96 asymptomatic children (p = 0.215). WU virus was detected in 26/367 (7.1%) symptomatic and 6/96 (6.3%) asymptomatic children (p = 1.00). These human polyomaviruses may not independently cause respiratory tract disease in young children. | 18,976,566 |
Porcine respiratory and reproductive syndrome virus variants, Vietnam and China, 2007. | We characterized isolates from porcine respiratory and reproductive syndrome virus epidemics in Vietnam and China in 2007. These isolates showed approximately 99% identity at the genomic level. Genetic analysis indicated that they share a discontinuous deletion of 30 aa in nonstructural protein 2, which indicates that ... | 18,976,568 |
Tourism and specific risk areas for Cryptococcus gattii, Vancouver Island, Canada. | We compared travel histories of case-patients with Cryptococcus gattii infection during 1999-2006 to travel destinations of the general public on Vancouver Island, British Columbia, Canada. Findings validated and refined estimates of risk on the basis of place of residence and showed no spatial progression of risk area... | 18,976,570 |
[Primary mucinous carcinoma of the skin--a literature review]. | Primary mucinous carcinoma of the skin (PKMK) is a rare malignant tumour of the sweat glands. It is often misdiagnosed as it has an uncharacteristic gross appearance - and may microscopically resemble a cutaneous metastasis from a mucinous carcinoma of the breast, gastrointestinal tract, lungs, ovaries or prostate. The... | 18,976,593 |
[The 3-hour meeting concept: an organisational approach for involvement of junior doctors in education]. | In an 850-bed Danish University hospital, "3-hour meetings" provide junior doctors with three hours within normal working hours for discussing training with an innovative purpose. The meetings are followed-up by dialogue and action throughout the organisation. The junior doctors get many of their training initiatives i... | 18,976,613 |
[Feedback in relation to training of practical clinical skills]. | Feedback has been identified as an essential component of motor learning. However, feedback principles derived from motor learning theories cannot uncritically be applied to clinical skills training because this knowledge is based primarily on the study of very simple motor skills. Research into feedback in relation to... | 18,976,616 |
[Perspectives on inspector visits in general practice]. | General practice has always provided teaching and training in some form or another, and recent years have seen a discussion on an appraisal system based on visits to practices. The educational dimension of general practice has been described in several publications. Training in general practice is highly esteemed. Even... | 18,976,618 |
[Career counselling and choice of speciality]. | Career counselling is meant to support and ensure an early and relevant choice of specialty. Self-awareness regarding personality, life goals, wishes for family life, and lifestyle is of help in narrowing down the number of specialties to those that fit personal attitudes and preferences. The counsellor must be aware t... | 18,976,620 |
Using LysoSensor Yellow/Blue DND-160 to sense acidic pH under high hydrostatic pressures. | LysoSensor Yellow/Blue DND-160, a dual-wavelength fluorophore commonly used for sensing pH in acidic organelles, possesses solvatochromic behavior believed to originate from an intramolecular charge transfer (ICT). Given this, we investigated whether DND-160 can be used for acidic pH sensing under hydrostatic pressures... | 18,976,626 |
Small molecule inhibition of a Group II chaperonin: pinpointing a loop region within the equatorial domain as necessary for protein refolding. | The functionality of regions within the equatorial domain of Group II chaperonins is poorly understood. Previously we showed that a 70 amino acid sequence within this domain on the single-subunit recombinant thermosome from Methanocaldococcus jannaschii (rTHS) contains residues directly responsible for refolding protei... | 18,976,628 |
Norepinephrine reversibly regulates the proliferation and phenotypic transformation of vascular smooth muscle cells. | To investigate the effect of norepinephrine (NE) on the proliferation and phenotypic transformation of vascular smooth muscle cells (VSMCs) and the mechanisms underlying this effect. VSMCs were isolated from the rat abdominal aorta. VSMCs cultured in both serum-containing or in a serum-free medium were treated with NE,... | 18,976,651 |
Elevated yolk androgen levels and the expression of multiple sexually selected male characters. | Maternal hormones in bird eggs modulate not only offspring development, but recently it has also been shown that these effects can persist into adult life. A number of long-lasting effects concern traits of which the expression or development is modulated by androgens. This suggests that the nature of yolk hormone-medi... | 18,976,657 |
Des-gamma-carboxy prothrombin increases the expression of angiogenic factors in human hepatocellular carcinoma cells. | Des-gamma-carboxyl prothrombin (DCP) is a serum protein produced by hepatocellular carcinoma (HCC) cells. The aim of this study was to evaluate the angiogenic activity of DCP in HCC cells. The proliferation of HCC cells was measured by 3-[4, 5-dimethylthiazol-2-yl]-2,5-diphenyl-tetrazolium bromide (MTT) assay. The grow... | 18,976,674 |
Genetic variants in the HLA-G region are associated with Kawasaki disease. | Kawasaki disease is an acute, self-limited vasculitis of infants and children, manifest as fever and signs of mucocutaneous inflammation. Treatment with high-dose immunoglobulin reduces systemic inflammation and prevents coronary artery lesions in Kawasaki disease. In this study, we investigated the possible associatio... | 18,976,687 |
Glossogin, a novel phenylpropanoid from Glossogyne tenuifolia, induced apoptosis in A549 lung cancer cells. | Glossogyne tenuifolia has been shown to exhibit good antioxidant and anticancer activity. In this study, a new phenylpropanoid compound, glossogin (1'-acetoxy-4-O-isovalyryleugenol), was isolated from ethyl acetate extract of G. tenuifolia by using column chromatography and HPLC. Its chemical structure was determined b... | 18,976,690 |
VEGFR-2 antagonist SU5416 attenuates bleomycin-induced pulmonary fibrosis in mice. | Abnormal angiogenesis is a central hallmark for the development and progression of idiopathic pulmonary fibrosis. It has been shown that vascular endothelial growth factor (VEGF) is one of the critical angiogenic factors in angiogenesis. The aim of the present study was to assess whether disruption of VEGF pathway woul... | 18,976,720 |
Identifying genetic traces of historical expansions: Phoenician footprints in the Mediterranean. | The Phoenicians were the dominant traders in the Mediterranean Sea two thousand to three thousand years ago and expanded from their homeland in the Levant to establish colonies and trading posts throughout the Mediterranean, but then they disappeared from history. We wished to identify their male genetic traces in mode... | 18,976,729 |
Three-dimensional power Doppler ultrasound scanning for the prediction of endometrial cancer in women with postmenopausal bleeding and thickened endometrium. | The purpose of this study was to evaluate the role of 3-dimensional power Doppler angiography (3D-PDA) to discriminate between benign and malignant endometrial disease in women with postmenopausal bleeding and thickened endometrium. Ninety-nine postmenopausal women (median age, 63.1 years; range, 48-84 years) with uter... | 18,976,731 |
Occupational factors and risk of preterm birth in nurses. | We evaluated first-trimester exposures and the risk of preterm birth in the most recent pregnancy of participants of the Nurses' Health Study II. Log binomial regression was used to estimate the relative risk (RR) for preterm birth in relation to occupational risk factors, such as work schedule, physical factors, and e... | 18,976,732 |
Ending cervical cancer screening: attitudes and beliefs from ethnically diverse older women. | Guidelines support ending cervical cancer screening in women aged 65-70 years and older with previous normal testing, but little is known about older women's attitudes and beliefs about ending screening. We conducted face-to-face interviews with 199 women aged 65 and older in English, Spanish, Cantonese, or Mandarin. M... | 18,976,734 |
Effects of probiotic Lactobacillus salivarius W24 on the compositional stability of oral microbial communities. | Probiotics are microorganisms beneficial to gastrointestinal health. Although some strains are also known to possess positive effects on oral health, the effects of most intestinal probiotics on the oral microflora remain unknown. We assessed the ability of the intestinal probiotic Lactobacillus salivarius W24 to incor... | 18,976,742 |
Comparison of low-dose human menopausal gonadotropin and micronized 17beta-estradiol supplementation in in vitro maturation cycles with thin endometrial lining. | A challenge of in vitro maturation (IVM) treatment in some women is insufficient development of the endometrium prior to embryo transfer. Retrospective study. McGill Reproductive Center, Montreal, Canada. Women with endometrial thickness <6 mm on days 6-10 ultrasound (US) scan of IVM treatment. In the human menopaus... | 18,976,750 |
Elevated ghrelin levels in the peritoneal fluid of patients with endometriosis: associations with vascular endothelial growth factor (VEGF) and inflammatory cytokines. | To study ghrelin concentrations in the peritoneal fluid of women with endometriosis and of control women without pelvic pathology and its associations with the levels of proinflammatory cytokines and vascular endothelial growth factor (VEGF). Case-control study. University research institution and hospital. Forty-six n... | 18,976,754 |
Aquaporin-4 deficiency induces subfertility in female mice. | To investigate the effects of aquaporin-4 (AQP4) on female fertility. Prospective, randomized animal study. Medical university. AQP4(+/+) and AQP4(-/-) female mice. Eight- to 10-week-old virgin female AQP4(+/+) and AQP4(-/-) mice were subjected to a mating study. Superovulation was carried out on 4-week-old AQP4(+/+) a... | 18,976,758 |
Advanced oxidation protein products are increased in women with polycystic ovary syndrome: relationship with traditional and nontraditional cardiovascular risk factors in patients with polycystic ovary syndrome. | To determine whether or not plasma advanced oxidation protein products (AOPPs) are associated with known cardiovascular risk factors or carotid intima-media thickness (IMT) in patients with polycystic ovary syndrome (PCOS). A prospective, controlled study. University hospital. Forty-six women with PCOS and 46 age- and ... | 18,976,759 |
Effect of progestogens and combined oral contraceptives on nerve fibers in peritoneal endometriosis. | To investigate how progestogens and combined oral contraceptives change nerve fiber density in peritoneal endometriotic lesions and to identify the types of nerve fibers still present during hormone treatment. Laboratory study using human tissue. University-based laboratory. Hormonally treated and untreated women with ... | 18,976,764 |
ST changes and temporal relation to the J point during heart rate increase and myocardial ischemia. | There is no concensus concerning where in the ST segment to measure. We studied the relation between different J point intervals to ST results during tachycardia and ischemia. Symptomatic (anesthetized) patients with coronary artery disease were paced at ascending incremental levels until they became ischemic. ST vecto... | 18,976,774 |
Three-dimensional relationship between the conus branch and the precordial leads confirmed by 64-multidetector-row computed tomography. | A 65-year-old man with effort angina pectoris underwent percutaneous coronary intervention of the proximal right coronary artery. The lesion was dilated with a bare-metal stent under wire protection of the conus branch (CB). However, the jailed CB was occluded. Electrocardiogram with conventional precordial leads (V(1)... | 18,976,781 |
Serial CSTR digester configuration for improving biogas production from manure. | A new configuration of manure digesters for improving biogas production has been investigated in laboratory scale. A single thermophilic continuous-flow stirred tank reactor (CSTR) operated with a hydraulic retention time (HRT) of 15 days was compared to a serial CSTR configuration with volume distribution ratio of 80/... | 18,976,792 |
Leukemic blast and natural killer cell P-glycoprotein function and inhibition in a clinical trial of zosuquidar infusion in acute myeloid leukemia. | A bioassay was developed to assess P-glycoprotein (P-gp) function of peripheral blood natural killer (NK) cells and AML blasts during zosuquidar infusion. Cells were incubated with the fluorescent dye DiOC(2)(3) in the presence and absence of zosuquidar, and dye accumulation measured by flow cytometry. The assay perfor... | 18,976,810 |
Dysphonia--a rare early symptom of Ehlers--Danlos syndrome? | Ehlers-Danlos syndrome is a connective tissue disorder characterized by joint hypermobility, skin hyperextensibility and cutaneous fragility. It usually presents in young adults and is rarely diagnosed in children. Voice involvement in young children, to our knowledge, has not been reported in the literature. We presen... | 18,976,821 |
Oral administration of heat-killed Lactobacillus brevis SBC8803 ameliorates alcoholic liver disease in ethanol-containing diet-fed C57BL/6N mice. | We examined the effect of heat-killed Lactobacillus brevis (L. brevis) SBC8803 on the development of alcoholic liver disease using ethanol-containing diet-fed mice. Heat-killed L. brevis was orally administered at a dose of 100 or 500 mg/kg once a day for 35 days. Alcoholic liver injury was examined by measuring the ac... | 18,976,829 |
X-ray absorption and photoelectron spectroscopy investigation of selenite reduction by FeII-bearing minerals. | The long-lived radionuclide 79Se is one of the elements of concern for the safe storage of high-level nuclear waste, since clay minerals in engineered barriers and natural aquifer sediments strongly adsorb cationic species, but to lesser extent anions like selenate (SeVIO4(2-)) and selenite (SeIVO3(2-)). Previous inves... | 18,976,832 |
Imitation of transitive and intransitive actions in healthy individuals. | A handful of patients have been described as being impaired in performing transitive gestures, despite being still able to perform intransitive gestures. This impairment need not be explained by assuming different mechanisms; rather, it can be due to transitive actions being more difficult. In this study we tested whet... | 18,976,850 |
Predicted concentrations of biocides from antifouling paints in Visakhapatnam Harbour. | The concentrations of biocides leached from antifouling coatings are monitored in most of the developed countries. However, in India and many other developing countries, there is very little data available on the concentrations of biocides in ports and harbours. The first step was to obtain the order of magnitude level... | 18,976,852 |
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