title stringlengths 0 1.13k | abstract stringlengths 1 15.7k | PMID int64 22 36.5M |
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Common polymorphisms in the vascular endothelial growth factor gene and colorectal cancer development, prognosis, and survival. | Angiogenesis plays an important role in growth, progression, and metastasis of tumors. The most important regulator of angiogenesis is vascular endothelial growth factor (VEGF). VEGF expression has been associated with advance stage and poor survival of several cancers. In the present study we evaluated the association... | 19,009,560 |
Diffusion-weighted imaging of the prostate and rectal wall: comparison of biexponential and monoexponential modelled diffusion and associated perfusion coefficients. | This study compares parameters from monoexponential and biexponential modelling of diffusion-weighted imaging of normal and malignant prostate tissue and normal rectal wall tissues. Fifty men with Stage Ic prostate cancer were studied using endorectal T(2)-weighted imaging and diffusion-weighted imaging with 11 diffusi... | 19,009,566 |
"Half-bonds" in an unusual coordinated S(4) (2-) rectangle. | Don't be square! A rare S(4) (2-) rectangle bridging two M(2)Cp(2)(mu(2)-CH(2))(2) (M=Rh, Ir) fragments is found to contain two "half-bonds" with S-S distances of 2.70 or 2.90 A. Computational studies explore the connection between these "half-bonds" and a Jahn-Teller distortion, as well as possible intermediates that ... | 19,009,582 |
Inflammation and sleep disordered breathing in children: a state-of-the-art review. | Sleep disordered breathing (SDB) represents a spectrum of breathing disorders, ranging from snoring to obstructive sleep apnea syndrome (OSAS), that disrupt nocturnal respiration and sleep architecture. OSAS is a common disorder in children, with a prevalence of 2-3%. It is associated with neurobehavioral, cognitive, a... | 19,009,600 |
Understanding patellofemoral pain with maltracking in the presence of joint laxity: complete 3D in vivo patellofemoral and tibiofemoral kinematics. | Patellofemoral pain is widely accepted as one of the most common pathologies involving the knee, yet the etiology of this pain is still an open debate. Generalized joint laxity has been associated with patellofemoral pain, but is not often discussed as a potential source of patellar maltracking. Thus, the objective of ... | 19,009,601 |
Predictive value of serologic markers in a population-based Norwegian cohort with inflammatory bowel disease. | Perinuclear antineutrophil cytoplasmic antibodies (pANCA) and anti-Saccharomyces cerevisiae antibodies (ASCA) are proposed to be specific markers for ulcerative colitis (UC) and Crohn's disease (CD). Their prevalence and relationship to disease phenotype and outcome in unselected cohorts of patients with inflammatory b... | 19,009,607 |
Feeding behavior and gene expression of appetite-related neuropeptides in mice lacking for neuropeptide Y Y5 receptor subclass. | Neuropeptide Y (NPY) is a potent neurotransmitter for feeding. Besides NPY, orexigenic neuropeptides such as agouti-related protein (AgRP), and anorexigenic neuropeptides such as alpha-melatonin stimulating hormone (MSH) and cocaine-amphetamine-regulated transcript (CART) are also involved in central feeding regulation... | 19,009,645 |
Ghrelin and Helicobacter pylori infection. | Ghrelin is primarily secreted from the stomach and has been implicated in the coordination of eating behavior and weight regulation. Ghrelin also plays an essential role in the mechanism of gastric mucosal defense. Thus, it is important to clarify which diseases primarily influence changes in plasma ghrelin concentrati... | 19,009,647 |
Effects of n-3 polyunsaturated fatty acids from seal oils on nonalcoholic fatty liver disease associated with hyperlipidemia. | To investigate the efficacy and safety of n-3 polyunsaturated fatty acids (PUFA) from seal oils for patients with nonalcoholic fatty liver disease (NAFLD) associated with hyperlipidemia. One hundred and forty-four patients with NAFLD associated with hyperlipidemia were included in the 24-wk, randomized, controlled tria... | 19,009,658 |
Regional anesthesia techniques for ambulatory orthopedic surgery. | The purpose of this review is to present advances in the use of regional anesthetic techniques in ambulatory orthopedic surgery. New findings regarding the use of both neuraxial anesthesia and peripheral nerve block are discussed. Neuraxial anesthesia: The use of short-acting local anesthetic agents such as mepivacaine... | 19,009,687 |
Web-based education in anesthesiology: a critical overview. | The purpose of this review is to discuss the rise of web-based educational resources available to the anesthesiology community. Recent developments of particular importance include the growth of 'Web 2.0' resources, the development of the concepts of 'open access' and 'information philanthropy', and the expansion of we... | 19,009,692 |
Impact of the model for end-stage liver disease allocation policy on the use of high-risk organs for liver transplantation. | Although priority for liver transplantation is determined by the model for end-stage liver disease (MELD) score, the quality of organs used is subject to physician discretion. We aimed to determine whether implementation of MELD affected the quality of organs transplanted, the type of patients who receive the higher-ri... | 19,009,713 |
Faculty awards at US colleges and schools of pharmacy. | To determine recognition given for outstanding teaching, service, and scholarship at US colleges and schools of pharmacy, the types of awards given, and the process used to select the recipients. A self-administered questionnaire was made available online in 2006 to deans at 89 colleges and schools of pharmacy. Sixty-f... | 19,009,732 |
Role of some biomarkers of atherogenic risk in the screening for molecular defects in the low density lipoprotein receptor in severe hypercholesterolemia. | Familial hypercholesterolemia is difficult to diagnose because of different expressions of the defective gene in low density lipoprotein (LDL) receptor mutation carriers and the presence of elevated LDL levels in noncarriers. To study specific biomarkers of atherogenic risk in carriers and noncarriers of low density li... | 19,009,746 |
[Immediate and long-term results of conventionally performed radiofrequency catheter ablations of paroxysmal atrial fibrillation]. | Atrial fibrillation is the most frequent cardiac arrhythmia. Epidemiological studies show sharp increase of incidence and prevalence of atrial fibrillation all over the world. Atrial fibrillation is becoming to be a serious problem, not only clinical, but even social and economical. Aim of the paper was to evaluate imm... | 19,009,761 |
In vivo assessment of Mg2+ in human brain and skeletal muscle by 31P-MRS. | Phosphorus magnetic resonance spectroscopy offers a unique opportunity to measure in vivo the free cytosolic magnesium [Mg2+] of different tissues. In particular, this technique has been employed in human brain and in skeletal muscle providing new hints on Mg2+ homeostasis and on its involvement in cellular bioenergeti... | 19,009,818 |
[Chronic obstructive pulmonary disease and infection]. | Patients with COPD are exposed to many infections of the lower respiratory tract. The evolution of their disease is characterized by an increasing number of episodes of exacerbation associated with a worsening dyspnea and an increase of the sputum volume and purulence. Fifty to 80% of these episodes are due to bacteria... | 19,009,845 |
Is intraocular pressure in myotonic dystrophy patients spuriously low? | Ocular hypotony is a common unexplained feature of myotonic dystrophy type 1. Spuriously low applanation tonometric readings can be caused by thin corneas, flat corneal curvature and corneal edema. To determine whether structure abnormalities of the cornea cause spuriously low readings in applanation tonometry. We util... | 19,009,949 |
Neuropathic pain in people treated for multibacillary leprosy more than ten years previously. | To identify patients with typical symptoms of neuropathic pain in a well-defined cohort of multibacillary patients being followed up as part of a relapse study in Ethiopia; to identify risk factors for the development of neuropathic pain. 96 patients who had completed MDT more than 10 years previously participated in t... | 19,009,976 |
Emissions of total volatile organic compounds and indoor environment assessment in dental clinics in Athens, Greece. | To quantify the amount of Total Volatile Organic Compounds (TVOCs) emitted from five dental substances commonly used in a dental clinic. An assessment of the indoor air quality in two clinics of the Athens University Dentistry Faculty was conducted. It was found that TVOC emissions from Kalocryl and Bacillol reached ex... | 19,009,994 |
The criminalisation of professional misconduct under the Health Professions Registration Act 2005 (VIC): how is a fine of $50,000 not punitive? | The purpose of medical boards is to protect patients and guide doctors. Courts and tribunals have constantly emphasised that their role is entirely protective and not punitive. By a huge increase in the fine that can be imposed on health professionals in Victoria to a level more commensurate with serious criminal activ... | 19,009,997 |
Apologies, medicine and the law. | This column considers some of the imperatives and barriers which may impact on a medical practitioner who apologises to a patient following an adverse event in New South Wales. It also considers the inclusion of the apology provisions in ss 67-69 of the Civil Liability Act 2002 (NSW) and the extent to which those provi... | 19,009,998 |
Preimplantation genetic diagnosis for susceptibility conditions: a new frontier or a logical extension? | A susceptibility or "lower penetrance" condition is a condition to which a person may be predisposed by virtue of a particular gene mutation they carry within their genetic code. Genetic testing for susceptibility to late-onset conditions, an increasingly available phenomenon, has recently been associated with preimpla... | 19,010,004 |
The non-compliance of clinical guidelines for organ donation with Australian statute law. | Organ procurement is possible under statutes defining death as either irreversible cessation of all functions of the brain or irreversible cessation of the circulation, thus fulfilling the "dead donor rule". However, present practice does not conform strictly to these conditions. Clinical guidelines for the diagnosis o... | 19,010,008 |
Development of human patient simulation programs: achieving big results with a small budget. | The benefits of simulation in nursing education are well documented. Nursing students learn in a safe environment that enhances critical thinking and collaboration. Barriers to simulation include cost, resources, and fear of technology. This article describes how to design and implement a quality simulation program for... | 19,010,052 |
Tracking the prevalence of rollover protective structures on U.S. farm tractors: 1993, 2001, and 2004. | Between 1992 and 2005, 1412 workers on farms died from tractor overturns. A Rollover Protective Structure (ROPS) is a proven intervention to reduce overturn deaths. However, farm characteristics that are associated with the adoption of ROPS are not well understood. ROPS prevalence statistics were derived from National ... | 19,010,124 |
Increased organ donations from people born outside Spain. | Organs donated from persons born outside Spain are becoming increasingly numerous. These persons now account for 26.1% of all donors in the "Malaga sector," an area of tourism with a high percentage of immigrants. Acceptance to donation among persons from Europe and South America is similar to that of Spanish persons b... | 19,010,131 |
Induction treatment with low-dose thymoglobulin or basiliximab in renal transplants from older donors. | Transplantation of kidneys from older donors is followed by an increase in delayed graft function (DGF) and acute rejection episodes (ARE). In these circumstances, induction treatment, whether with antithymocyte globulin or with interleukin-2 receptor blockers, may delay the introduction of calcineurin inhibitors (CNI)... | 19,010,141 |
Left ventricular structure and function in long-term kidney transplantation: the influence of glucose metabolism and oxidative stress. | Impaired cardiac structure and function are fundamental components of cardiovascular disease, leading to morbidity, mortality, and graft loss after renal transplantation. The aim of this study was to describe and determine the factors involved in these cardiac abnormalities, paying special attention to the role of gluc... | 19,010,145 |
Hepatitis C virus infection after renal transplantation. | Hepatitis C virus (HCV) infection is the main cause of liver disease after renal transplantation. Most patients have seroconverted on dialysis to positive RNA. The viral load increases during immunosuppressive therapy. The risk of developing chronic liver disease is related to the histopathologic findings, duration and... | 19,010,152 |
Cancer incidence and survival in kidney transplant patients. | Immunosuppression after organ transplantation is associated with a markedly increased risk of nonmelanoma skin cancer (NMSC) and malignancies, including posttransplant lymphoproliferative disorder (PTLD) and solid organ cancer. This study sought to investigate the incidence of malignancies and the clinical characterist... | 19,010,153 |
Response to a vaccination schedule with 4 doses of 40 microg against hepatitis B virus in cirrhotic patients evaluated for liver transplantation. | We conducted a retrospective study to evaluate the response to recombinant hepatitis B vaccine after 4 intramuscular doses (40 microg) administered at 0, 1, 2, and 6 months in 157 cirrhotic patients who were liver transplant candidates. Seventeen nonresponders were revaccinated with the same schedule. We studied the as... | 19,010,154 |
Hypertension after heart transplantation: predictive factors and number and classes of drugs for its management. | This study was performed to determine the factors that cause arterial hypertension after heart transplantation (HT) and the drugs used in its management. We studied 247 consecutive patients who had undergone HT between 2000 and 2006 and who survived for at least 6 months. We excluded patients who received combination t... | 19,010,190 |
Prognostic factors influencing survival rates in children following lung transplantation. | To assess the results of lung transplantation (LT) in children under 17 years of age and identify factors affecting long-term survival. A retrospective review was performed of 37 patients (<17 years) who had received a lung transplant between 1996 and 2007. Morbidity, mortality, and survival were analyzed by the Kap... | 19,010,197 |
Results of lung transplantation in patients with chronic obstructive pulmonary disease. | The objective of this study was to evaluate the results and survival rates of patients who underwent lung transplantation (LT) to treat chronic obstructive pulmonary disease (COPD). We performed a retrospective analysis of 63 patients with COPD who underwent LT between 1996 and 2007. Our statistical analysis was based ... | 19,010,198 |
Experience of the Reina Sofia Hospital in lung transplantation from donors older than forty years. | The shortage of suitable donors for lung transplantation (LT) has led to liberalization of criteria for donor selection. This study evaluated the outcomes of LT among a subset of patients receiving organs from standard donors older than 40 years of age. We distributed patients who underwent LTs performed between 1993 a... | 19,010,200 |
Selective transarterial chemoembolization of advanced hepatocellular carcinomas: a reasonable palliative option. | The purpose of this study was to provide information concerning the performance of selective transarterial chemoembolization (TACE) as a palliative treatment in patients with hepatocellular carcinoma (HCC), also in the case of multifocal lesions. We reviewed prospectively collected data on 43 patients with cirrhosis an... | 19,010,226 |
The evolution of the role of liver transplantation in treating alcoholic cirrhosis in Greece. | Liver transplantation represents the main treatment for alcoholic cirrhosis. The goal of this article is to review the results of liver transplantation for alcoholic cirrhosis in Greece over the last 2 decades. Among 247 patients who underwent liver transplantation between 1991 and 2007, 34 (13.7%) experienced alcoholi... | 19,010,229 |
NMD: multitasking between mRNA surveillance and modulation of gene expression. | Gene expression is a highly specific and regulated multilayer process with a plethora of interconnections as well as safeguard and feedback mechanisms. Messenger RNA, long neglected as a mere subcarrier of genetic information, is more recently recognized as a linchpin of regulation and control of gene expression. Moreo... | 19,010,255 |
Human papillomavirus in HNSCC: a European epidemiologic perspective. | The aim of this study was to assess incidence and survival of human papillomavirus-related and unrelated head and neck squamous cell carcinoma sites from 15 European population-based cancer registries. This analysis was performed on 29,265 adult (aged approximately 15 years) cancer patients diagnosed in the period from... | 19,010,264 |
Induction chemotherapy in locally advanced head and neck cancer: a new standard of care? | Locally advanced squamous cell cancer of the head and neck is a major contributor to morbidity and mortality worldwide. Despite progress through the use of multimodality treatment involving surgery, radiotherapy, and chemotherapy in recent years, the survival remains poor, and treatment-related morbidity-mainly caused ... | 19,010,265 |
Molecularly targeted agents in the treatment of recurrent or metastatic squamous cell carcinomas of the head and neck. | Proof of principle that molecularly targeted therapy is a valid therapeutic approach for squamous cell carcinoma of the head and neck (SCCHN) has emerged with epidermal growth factor receptor targeting agents. Other interesting targets, such as Src, insulin-like growth factor 1 receptor, and the proteasome, have been s... | 19,010,269 |
Sinonasal malignancies of neuroendocrine origin. | The sinonasal malignancies of putative neuroendocrine origin-esthesioneuroblastoma, sinonasal neuroendocrine carcinoma, sinonasal undifferentiated carcinoma, and sinonasal small cell carcinoma-are uncommon malignancies that frequently present with locally advanced disease. Pathologic distinction between these entities ... | 19,010,275 |
Pancoast tumors. | Pancoast tumors (superior sulcus tumors or apical lung tumors) typically invade structures at the thoracic outlet, including the inferior elements of the brachial plexus (C8, T1 nerve roots and lower trunk). Historically, these tumors are rapidly fatal, but newer treatment with induction chemotherapy and radiotherapy, ... | 19,010,280 |
What's new in common upper extremity entrapment neuropathies. | Upper extremity entrapment neuropathies are common and disabling, and correct diagnosis is essential for proper management. This article is a review of the recent developments related to diagnosis and treatment of common upper extremity nerve entrapments, including novel treatment strategies for suprascapular, median, ... | 19,010,282 |
A readapted Malone schistosome transmission index model. | Schistosome transmission index can be directly used to give an overall evaluation and prediction of schistosomiasis transmission through a mathematical model. In the light of the mechanism of schistosomiasis transmission process, an improved Malone schistosome transmission index model was established based on the previ... | 19,010,297 |
A rapid gas chromatography-mass spectrometry method for quantification of alkylresorcinols in human plasma. | Alkylresorcinols (ARs) are phenolic lipids that among foods are found almost exclusively in whole grain and bran products based on wheat and rye. They have been suggested to be used as selective biomarkers of whole grain wheat and rye intake and, thus, may serve as an alternative/complement to commonly used dietary ass... | 19,010,298 |
Structure, membrane orientation, mechanism, and function of pexiganan--a highly potent antimicrobial peptide designed from magainin. | The growing problem of bacterial resistance to conventional antibiotic compounds and the need for new antibiotics have stimulated interest in the development of antimicrobial peptides (AMPs) as human therapeutics. Development of topically applied agents, such as pexiganan (also known as MSI-78, an analog of the natural... | 19,010,301 |
Effects of different corticosteroids on the brain weight and hippocampal neuronal loss in rats. | Equivalent antiinflammatory doses of steroids including betamethasone, methylprednisolone and dexamethasone were administered in the neonatal period in a rat model. In situ cell death in hippocampus quantified by Terminal Deoxynucleated Transferase Nick-End Labeling and on ratio of brain to body weight was investigated... | 19,010,310 |
Type 5 17beta-hydroxysteroid dehydrogenase/prostaglandin F synthase (AKR1C3): role in breast cancer and inhibition by non-steroidal anti-inflammatory drug analogs. | Aldo-keto reductase (AKR) 1C3 catalyzes the NADPH-dependent reduction of Delta(4)-androstene-3,17-dione to yield testosterone, reduction of estrone to yield 17beta-estradiol and reduction of progesterone to yield 20alpha-hydroxyprogesterone. In addition, it functions as a prostaglandin (PG) F synthase and reduces PGH(2... | 19,010,312 |
Differential action of methylselenocysteine in control and alloxan-diabetic rabbits. | Antidiabetic action of inorganic selenium compounds is commonly accepted. Since in diet selenium mainly exists as selenoamino acids, potential hypoglycemic properties of methylselenocysteine (MSC) were investigated in four groups of rabbits: untreated and MSC-treated control animals as well as alloxan-diabetic and MSC-... | 19,010,315 |
Mass spectrometry based metabolomic approaches in urinary biomarker study of women's cancers. | The metabolomic approaches for mining biomarkers of women's cancers based on gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry combined with partial least squares-discriminant analysis are described. To identify urinary potential biomarkers, the qualitative and quantitative analyses were ... | 19,010,317 |
Characteristics of a novel Pseudomonas aeruginosa bacteriophage, PAJU2, which is genetically related to bacteriophage D3. | Pseudomonas aeruginosa bacteriophage (phage) is one of the most taxonomically and genetically diverse phages. Although phage D3 is one of well-studied P. aeruginosa phages, no D3-related P. aeruginosa phage has been reported. We report a novel P. aeruginosa siphovirus, PAJU2, which is genetically related to but morphol... | 19,010,363 |
Characterization of a concealed antigen Hq05 from the hard tick Haemaphysalis qinghaiensis and its effect as a vaccine against tick infestation in sheep. | Positive clone Hq05 of Haemaphysalis qinghaiensis (named following those cDNA clones cloned from the tick before) was obtained by differentially screening of a cDNA library of the tick with rabbit anti-tick salivary gland serum and rabbit anti-tick saliva serum. Hq05 contains an open reading frame (ORF) of 540bp that c... | 19,010,370 |
A four-stage strategy to reduce childhood pneumonia-related mortality by 2015 and beyond. | The global community has considered several vaccines to reduce pneumonia morbidity and mortality among children <5 years. Recent burden estimates support pneumococcal vaccine introduction, however, influenza vaccine has received only recent attention. The effect of influenza vaccine on early childhood pneumonia has ... | 19,010,371 |
Quantum-like model of cognitive decision making and information processing. | In this paper we offer the quantum-like (QL) representation of the Shafir-Tversky statistical effect which is well known in cognitive psychology. We apply the so-called contextual approach. We consider the Shafir-Tversky effect to result from mixing statistical data obtained in incompatible contexts which are involved,... | 19,010,383 |
Sex differences in the neuroanatomy of human mirror-neuron system: a voxel-based morphometric investigation. | Females frequently perform better in empathy, interpersonal sensitivity, and emotional recognition than do males. The mirror-neuron system has been proposed to play an important role in social cognition. It remains to be clarified, however, whether the neuroanatomy underlying the human mirror neuron system exhibits sex... | 19,010,397 |
Preparation of ultrafine fenofibrate powder by solidification process from emulsion. | The solidification process from emulsion, which consisted of emulsifier, water and molten drug as oil phase without use of any organic solvent, was firstly employed to prepare ultrafine fenofibrate (FF) powder. The effects of stirring speed and volume ratios of hot emulsion to cold water on the particle size and morpho... | 19,010,406 |
Oligonucleotide-based assays for integrase activity. | Oligonucleotide assays have been invaluable for elucidation of the molecular mechanisms of retroviral integrases. A suite of rapid and sensitive fluorescence assays to measure the DNA binding, processing, and joining activities of integrase (IN) is described here. The assays are especially useful for characterizing the... | 19,010,419 |
The alpha-1-antitrypsin gene promoter in human A549 lung derived cells, and a novel transcription initiation site. | Alpha-1-antitrypsin (AAT), also called serine proteinase inhibitor A1 (Serpin A1), is the most abundant serpin in human plasma. A major physiological role of AAT is to protect the lung from the destructive effects of excess uninhibited neutrophil elastase. During inflammation, circulating levels of AAT may increase two... | 19,010,440 |
Phylogeography and evolutionary history of dengue virus type 3. | In this study, we revisited the phylogeography of the three of major DENV-3 genotypes and estimated its rate of evolution, based on the analysis of the envelope (E) gene of 200 strains isolated from 31 different countries around the world over a time period of 50 years (1956-2006). Our phylogenetic analysis revealed a ... | 19,010,450 |
Deletion of bradykinin B1 receptor reduces renal fibrosis. | The Kallikrein-kinin system works through activation of two receptors. One constitutive, named B2 receptor (B2R) and another inducible, denominated B1 receptor (B1R). In renal fibrosis, B2R receptor activation appears to be protective, however B1R participation is unveiled. The aim of this study was to analyze how the ... | 19,010,452 |
Neuropeptide Y (NPY) and NPY Y1 receptor in periodontal health and disease. | Neuropeptide Y (NPY) coordinates inflammation and bone metabolism which are central to the pathogenesis of periodontitis. The present study was designed to determine whether NPY was quantifiable in human gingival crevicular fluid (GCF) and to test the null hypothesis that GCF levels of NPY were the same in periodontal ... | 19,010,457 |
Diabetes causes the accelerated loss of cartilage during fracture repair which is reversed by insulin treatment. | Fracture healing in diabetic individuals and in animal models of diabetes is impaired. To investigate mechanisms by which diabetes may affect fracture healing we focused on the transition from cartilage to bone, a midpoint in the fracture healing process. Femoral fractures were induced in mice rendered diabetic by mult... | 19,010,456 |
A probabilistic corpus-based model of syntactic parallelism. | Work in experimental psycholinguistics has shown that the processing of coordinate structures is facilitated when the two conjuncts share the same syntactic structure [Frazier, L., Munn, A., & Clifton, C. (2000). Processing coordinate structures. Journal of Psycholinguistic Research, 29(4) 343-370]. In the present ... | 19,010,463 |
The effects of the extraocular muscles on eye impact force-deflection and globe rupture response. | There are over 1.9 million eye injuries per year in the United States, with blunt impacts the cause of approximately one-half of all civilian eye injuries. No previous experimental studies have investigated the effects of the extraocular muscles on the impact response of the eye. A spring-powered blunt impactor was use... | 19,010,469 |
Depletion of high-abundance proteins from human plasma using a combination of an affinity and pseudo-affinity column. | Human serum albumin (HSA) and immunoglobulin G (IgG) represent over 75% of all proteins present in human plasma. These high-abundance proteins prevent the detection of low-abundance proteins which are potential markers for various diseases. The depletion of HSA and IgG is therefore essential for further proteome analys... | 19,010,473 |
Quantification of the interactions between a cationic dye and humic substances in aqueous solutions. | Humic substances (HS) are ubiquitous in natural waters. Due to their plentiful binding sites, HS play an important role in the mobilization and transport of pollutants in natural environments. However, the presence state of HS causes difficulty in exploring the interactions between HS and pollutants in aqueous solution... | 19,010,483 |
Wettability of model fountain solutions: the influence on topo-chemical and -physical properties of offset paper. | The surface chemical and physical character of offset paper was studied before and after application of model fountain solutions based on isopropyl alcohol and an alcohol-free surfactant solution. The paper surface features were characterised with atomic force microscopy and the surface energies were determined by cont... | 19,010,484 |
Prediction of Salmonella in seawater by total and faecal coliforms and Enterococci. | The power of total coliforms (TC), faecal coliforms (FC) and Enterococci to predict the presence of Salmonella in seawater was investigated. Indicator cut-off values with the most satisfactory combination of sensitivity and specificity in predicting Salmonella presence were 1,000 CFU 100ml(-1)TC, 200 CFU 100ml(-1)FC, 5... | 19,010,501 |
Developmental levels of phospholipase D isozymes in the brain of developing rats. | The developmental levels of phospholipase D (PLD) isozymes was examined in the cerebrum and hindbrain of the developing rat to better understand the involvement of PLD in brain development. Western blot analysis of PLD in the cerebrum showed that PLD1, a major PLD isoform in the brain, was detected weakly in the cerebr... | 19,010,519 |
The clinical significance of hepatic parenchymal metastasis in patients with primary epithelial ovarian cancer. | The objective of this study was to determine the clinical significance of hepatic parenchymal metastasis on survival in patients with advanced epithelial ovarian cancer. We conducted a retrospective review of ovarian cancer patients with stages IIIc and IV hepatic parenchymal metastasis who were treated at the National... | 19,010,521 |
The effect of RGD density on osteoblast and endothelial cell behavior on RGD-grafted polyethylene terephthalate surfaces. | Hybrid materials combining polyethylene terephthalate and different types of cells (endothelial and osteoblastic cells) have been developed thanks to the covalent grafting of different densities of RGD containing peptides onto the polymer surface. Biomimetic modifications were performed by means of a three-step reactio... | 19,010,529 |
The geometric control of E14 and R1 mouse embryonic stem cell pluripotency by plasma polymer surface chemical gradients. | Plasma polymer surfaces were fabricated such that the cell response to a range of carboxylic acid concentrations on a single sample could be investigated. Surface chemical gradients from hydrophobic plasma polymerised octadiene (OD) to a more hydrophilic plasma polymerised acrylic acid (AA) were formed on glass coversl... | 19,010,532 |
Induction of apoptosis in leukemic cell lines treated with captopril, trandolapril and losartan: a new role in the treatment of leukaemia for these agents. | Renin-angiotensin system (RAS) in the bone marrow is related to proliferation and cellular differentiation. We investigated the effect of ACE inhibitors (ACEI) captopril (>1mM) and trandolapril (>0.05 mM) and losartan (0.2 mM) on K562 cell line and K562 transfected with c-myc, bcl-x and bcl-2 (KmycB, Kbclx and Kb... | 19,010,543 |
Influenza vaccination coverages among children, adults, health care workers and immigrants in Spain: related factors and trends, 2003-2006. | This study sought to: describe influenza vaccination coverage among Spanish children, adults, health care workers (HCWs), and immigrants according to the 2006 Spanish National Health Survey (NHS); and analyze the time trend for the period 2003-2006. We analyzed 38,329 questionnaires drawn from the 2006 NHS, covering su... | 19,010,553 |
Acute effects of three high-fat meals with different fat saturations on energy expenditure, substrate oxidation and satiety. | To compare the acute effects of three fatty meals with different fat quality on postprandial thermogenesis, substrate oxidation and satiety. Twenty-nine healthy men aged between 18 and 30 years participated in a randomised crossover trial comparing the thermogenic effects of three isocaloric meals: high in polyunsatura... | 19,010,571 |
Sampling atmospheric pesticides with SPME: Laboratory developments and field study. | To estimate the atmospheric exposure of the greenhouse workers to pesticides, solid phase microextraction (SPME) was used under non-equilibrium conditions. Using Fick's law of diffusion, the concentrations of pesticides in the greenhouse can be calculated using pre-determined sampling rates (SRs). Thus the sampling rat... | 19,010,574 |
A geospatial analysis of persons opting out of an exception from informed consent out-of-hospital clinical trial. | For trials involving exception from informed consent, some IRBs require that community members be allowed to "opt out" prior to enrollment. We tested for geospatial clustering of opt-out requests and the associated census tract characteristics in one study region. This was a retrospective study at a single site of a mu... | 19,010,580 |
The use of the laryngeal tube disposable (LT-D) by paramedics during out-of-hospital resuscitation-an observational study concerning ERC guidelines 2005. | In the current guidelines of the European Resuscitation Council (ERC), tracheal intubation, as an instrument for securing the airway during resuscitation, has become less important for persons not trained in this method. For those persons, different supraglottic airway devices are recommended by the ERC. The present in... | 19,010,582 |
The cutoff values of intrathecal interleukin 8 and 6 for predicting the neurological outcome in cardiac arrest victims. | To evaluate the changes in inflammatory cytokines, such as interleukin (IL)-8 and IL-6, in the cerebrospinal fluid (CSF) and serum, and to identify any correlations with the neurological outcomes in patients resuscitated from cardiopulmonary arrest (CPA). This study was designed as a prospective clinical trial. Thirtee... | 19,010,583 |
Dibucaine effects on structural and elastic properties of lipid bilayers. | In this work we report the interaction effects of the local anesthetic dibucaine (DBC) with lipid patches in model membranes by Atomic Force Microscopy (AFM). Supported lipid bilayers (egg phosphatidylcholine, EPC and dimyristoylphosphatidylcholine, DMPC) were prepared by fusion of unilamellar vesicles on mica and imag... | 19,010,585 |
Isolation of Ochrobactrum sp.QZ2 from sulfide and nitrite treatment system. | A bacterial strain QZ2 was isolated from sludge of anoxic sulfide-oxidizing (ASO) reactor. Based on 16S rDNA sequence analysis and morphology, the isolate was identified as Ochrobactrum sp. QZ2. The strain was facultative chemolithotroph, able of using sulfide to reduce nitrite anaerobically. It produced either element... | 19,010,594 |
Liquid phase microextraction and ultratrace determination of cadmium by modified graphite furnace atomic absorption spectrometry. | A powerful microextraction technique was used for determination of cadmium in water samples using liquid phase microextraction (LPME) followed by graphite furnace atomic absorption spectrometry (GF-AAS). In a preconcentration step, cadmium was extracted from a 2 ml of its aqueous sample in the pH 7 as 5,7-dibromoquinol... | 19,010,596 |
Self-initiated tobacco cessation and substance use outcomes among adolescents entering substance use treatment in a managed care organization. | Adolescents with substance use (SU) problems have high rates of tobacco use, yet SU treatment has historically ignored treatment for tobacco use. Barriers to such efforts include the belief that tobacco cessation could compromise other SU abstinence. This study examines self-initiated tobacco cessation and 12-month alc... | 19,010,600 |
Epidemiology of risk factors and symptoms associated with menopause in Spanish women. | (1) To assess the prevalence of risk factors for osteoporosis and cardiovascular disease and the prevalence and severity of the appearance of menopausal symptoms among Spanish menopausal women. (2) To identify the main factors responsible for this severity. (3) To detect symptom differences between perimenopausal and p... | 19,010,615 |
2-Methoxyestradiol attenuates hypertension and coronary vascular remodeling in spontaneously hypertensive rats. | Accumulating data provide evidence that some metabolites of 17beta-estradiol are biologically active and mediate multiple effects on the cardiovascular and renal systems. We investigated the effect of 2-methoxyestradiol (an active metabolite of estradiol with non-feminizing activity) on the development of hypertension ... | 19,010,616 |
Role of an anti-acetonemic diet in reducing the need for tonsillectomy in children with recurrent tonsillitis. | The aim of this study was to investigate the effectiveness of an anti-acetonemic diet in reducing the need for tonsillectomy especially in the first years of life in children with recurrent tonsillitis. From 2002 to 2005 we carried out a prospective randomized study enrolling 1200 children aged 2-10 who were referred t... | 19,010,622 |
C-kit protein expression in Wilms' tumour: an immunohistochemical study. | The use of a non-toxic tyrosine kinase receptor inhibitor, Imatinib Mesylate (IM), has become an ever-more common therapeutic alternative in some Kit (CD117) over-expressing neoplasms. As the treatment eligibility for these drugs hinges on CD117 expression, Kit immunostaining has recently been widely examined in variou... | 19,010,635 |
[Inflammation and acute brain injuries in intensive care]. | Patients with acute brain injuries or susceptibility to post-surgery stroke are a major therapeutic challenge for intensive care and anaesthesiology medicine. The control of systemic stress involved in brain damage is necessary to reduce the frequency and severity of secondary brain lesions. Inflammation is known to be... | 19,010,639 |
A pharmaceutical preparation of Salvia miltiorrhiza protects cardiac myocytes from tumor necrosis factor-induced apoptosis and reduces angiotensin II-stimulated collagen synthesis in fibroblasts. | Salvia miltiorrhiza is a medicinal herb commonly used in traditional Chinese medicine for the prevention and treatment of cardiovascular disease. This study investigated the effects of Cardiotonic Pill (CP), a pharmaceutical preparation of Salvia miltiorrhiza, on cardiac myocytes and fibroblasts with respect to the via... | 19,010,649 |
Social injecting and other correlates of high-risk sexual activity among injecting drug users in northern Vietnam. | Sexual risk and STDs are relatively high among injecting drug users (IDUs) in Vietnam. We sought to determine characteristics of sexually active IDUs and correlates of high-risk sexual practices among IDUs in Bac Ninh province in northern Vietnam. We used data collected for a community-based cross-sectional pilot study... | 19,010,656 |
A glucose biosensor based on Prussian blue/chitosan hybrid film. | Based on electrodeposition of Prussian blue (PB) and chitosan (CS) directly on gold electrode, a hybrid film of PB/CS has been prepared. PB in this film shows a good stability compared with pure PB film when it worked in neutral and weak alkalescent solution and can act as redox mediator. It provides the potential appl... | 19,010,659 |
Treatment and phosphorus removal from high-concentration organic wastewater by the yeast Hansenula anomala J224 PAWA. | A flocculent yeast, Hansenula anomala J224 PAWA, bred in this study, accumulated twice as much phosphorus as the wild type. Over a 30-d period, PAWA removed 70-80% of dissolved total phosphorus from sweet-potato and barley shochu wastewaters (alcoholic distillery wastewaters) while the wild type removed only 30%. Waste... | 19,010,663 |
Synthesis and antiinflammatory activity of some new 1,3,5-trisubstituted pyrazolines bearing benzene sulfonamide. | Nineteen new 2-pyrazoline bearing benzenesulfonamide derivatives were synthesized by condensing chalcones with 4-hydrazinonbenzenesulfonamide hydrochloride. Their chemical structures were proved by means of IR, (1)H NMR, (13)C NMR, mass spectroscopic and elemental analyses data. These compounds were tested at dose of 2... | 19,010,670 |
N,N-Dichloroaminosulfonic acids as novel topical antimicrobial agents. | 2-Dichloroamino-2-methyl-propane-1-sulfonic acid sodium salt (2a), a stable derivative of endogenous N,N-dichlorotaurine (1), has been identified and is under development as a topical antimicrobial agent. Structure-activity relationships of analogs were explored to achieve optimal antimicrobial activity with minimal ma... | 19,010,674 |
Engineered production of iso-migrastatin in heterologous Streptomyces hosts. | Glutarimide-containing polyketides such as migrastatin (MGS) are well known for their ability to inhibit tumor cell migration. We have previously shown that MGS is derived from iso-migrastatin (iso-MGS) via a H(2)O-mediated ring-expansion rearrangement. A bacterial artificial chromosome (BAC) library of Streptomyces pl... | 19,010,685 |
[Two observations of evisceration after caesarean section performed according the so-called Stark procedure]. | Two cases of evisceration after caesarean sections performed according the Misgav Ladach General Hospital procedure (Stark's procedure) are reported. In these cases, omentum was sutured between the edges of fascia recti, creating a weakness of the abdominal sheath. These cases claim about a strict procedure for fascia ... | 19,010,708 |
Optical test strip for trace Hg(II) based on doped sol-gel film. | Optical test strip based on the use of Br-PADAP as a sensitive reagent immobilised into sol-gel thin film for detection of Hg(II) in aqueous solution had been thoroughly carried out. It has a square-sensing zone (1.0 cm x 1.0 cm) containing the sensitive reagent necessary to produce response to trace level of mercury. ... | 19,010,723 |
The spectroscopic detection of drugs of abuse in fingerprints after development with powders and recovery with adhesive lifters. | The application of powders to fingerprints has long been established as an effective and reliable method for developing latent fingerprints. Fingerprints developed in situ at a crime scene routinely undergo lifting with specialist tapes and are then stored in evidence bags to allow secure transit and also to preserve t... | 19,010,725 |
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