title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
|---|---|---|---|
An enzyme-linked immunosorbent assay for the detection of canine antibodies to canine adenoviruses. | An enzyme-linked immunosorbent assay was used to detect canine immunoglobulin G antibodies specific for infectious canine hepatitis virus and the serologically related canine adenovirus Type 2. The sequential development of homologous and heterologous antibodies was measured by the enzyme-linked immunosorbent assay and... | 229,339 | [
-0.005484086,
0.1140165,
-0.1544691,
-0.07483763,
0.02888867,
-0.1715454,
-0.3535601,
0.1961681,
-0.1522387,
0.1966307,
0.2192025,
0.2740749,
0.02317358,
0.08951131,
-0.4173367,
-0.05406229,
-0.2049101,
0.3623877,
0.02183501,
-0.03796983,
0.1614573,
-0.1811063,
-0.0991926... |
Studies on sphingomyelinase activity in cultured cells and leucocytes. | Using both [3H]ceramide-sphingomyelin and [14C]methyl choline-sphingomyelin as substrate, enzyme activity was determined in skin fibroblasts, cultured amniotic fluid cells and leucocytes. Sphingomyelinase activities of fibroblasts from two patients with Niemann-Pick disease were about 1% of the mean control values (22.... | 229,341 | [
-0.2215626,
-0.3862913,
-0.4180549,
-0.2530382,
0.1614839,
0.1181268,
-0.3843384,
-0.05761051,
0.1928259,
-0.3089431,
0.07698207,
0.01173024,
0.03339544,
0.2386176,
-0.2428212,
0.03632008,
-0.5617828,
0.1534134,
-0.3028026,
0.4543128,
0.1575104,
0.2568216,
-0.2178192,
-... |
Anderson-Fabry disease: rapid detection of carriers by hair bulb analysis. | A rapid and simple method is described for the identification of the carrier state in angiokeratoma corporis diffusum. The alpha-galactosidase (alpha-D-galactoside galactohydrolase, E.C.3.2.1.22) activities in individual hair roots are measured and compared with those of N-acetyl-beta-hexosaminidase (E.C.3.2.1.30), ano... | 229,342 | [
-0.04460208,
-0.332231,
-0.3552056,
0.1233496,
-0.03827122,
-0.2903777,
-0.04004589,
-0.2322542,
-0.05494927,
0.2236667,
0.01416403,
0.5308638,
-0.05266143,
0.2528416,
-0.2816085,
-0.1653273,
-0.3177894,
-0.06721447,
0.1220479,
-0.3165737,
0.2838161,
0.301199,
-0.04142332... |
Facial nerve function in 100 consecutive parotidectomies. | The risk of facial nerve paresis after parotidectomy is thought to be within acceptable limits, although it is difficult to find published data regarding the specific magnitude of this risk. This study reviews the subject and reports postoperative facial function in 100 consecutive patients who had parotidectomies at t... | 229,363 | [
-0.3773423,
-0.4042256,
-0.4220053,
-0.4208479,
-0.2954806,
-0.3585785,
-0.1127538,
0.2886501,
-0.0610805,
-0.0329912,
0.08606109,
-0.1712821,
0.2398646,
-0.4296879,
0.1483516,
-0.2471056,
-0.01908228,
-0.05566594,
0.03775388,
-0.06724637,
0.2900549,
0.03933273,
0.1057413... |
[Experimental silicosis. I. Fibrogenic activity of quartz material used in the ceramic industry]. | A high concentration of silica dust in the air many workstands in ceramic plants is a serious risk for the health of exposed workers. It can cause the development of silicosis. The aim of this paper is to evaluate a fibrogenic activity of dusts containing 98% crystalline silica. The ceramic masses have about 25% of Qua... | 229,382 | [
0.0262497,
-0.09943114,
0.1516575,
0.3373824,
0.01943549,
-0.1683018,
-0.1596899,
0.06704392,
0.1009605,
0.1558129,
0.2897782,
-0.5240518,
0.1968288,
-0.4291875,
-0.3557166,
0.06619765,
-0.2309922,
-0.1237611,
0.3662052,
0.1384857,
0.1237431,
0.5838603,
-0.1273797,
0.23... |
Anion transport in red blood cells. II. Kinetics of reversible inhibition by nitroaromatic sulfonic acids. | The anion exchange system of human red blood cells is highly inhibited and specifically labeled by isothiocyano derivatives of benzene sulfonate (BS) or stilbene disulfonate (DS). To learn about the site of action of these irreversibly binding probes we studied the mechanism of inhibition of anion exchange by the rever... | 229,385 | [
-0.09566381,
0.00735265,
0.01504807,
-0.2180873,
0.568453,
-0.02001366,
-0.01993534,
0.2385817,
-0.01648788,
0.1174077,
0.04200537,
0.3586535,
-0.06522198,
0.2312125,
-0.7558222,
-0.2730793,
-0.547327,
0.06263807,
0.04301687,
0.3160976,
0.2617945,
0.109904,
-0.1216739,
... |
The opiate antagonist, naloxone, does not affect descending inhibition from midbrain of nociceptive spinal neuronal discharges in the cat. | Discharges were recorded from spinal dorsal horn neurons in response to noxious skin heating (e.g. 50 degrees C). Repetitive electrical stimulation of the mesencephalic periaqueductal gray (PAG) inhibited these nociceptive discharges. In each of 9 experiments systemic administration of naloxone (1-3 mg/kg) did not affe... | 229,438 | [
0.2495598,
-0.06562956,
-0.2966021,
-0.07575265,
0.1493375,
0.0307734,
0.09545469,
-0.324029,
-0.1047895,
-0.263952,
0.1106078,
0.1752656,
0.3595592,
-0.05676237,
-0.07420701,
-0.09633891,
-0.4934844,
0.031209,
0.2089324,
-0.02606695,
0.09957419,
0.3134958,
-0.1572204,
... |
Determination of the length distribution of poly(A) at the 3' terminus of the virion RNAs of EMC virus, poliovirus, rhinovirus, RAV-61 and CPMV and of mouse globin mRNA. | Rapid, detailed, and accurate analysis of the length spectrum of 3' terminal poly(A) in an RNA population can be obtained by 3'-terminal 32P-labelling of RNA with T4 RNA ligase, digestion with ribonucleases T1 and A, and use of gel sequencing methods. Length distributions of 3'-terminal poly(A) of EMC virus, poliovirus... | 229,465 | [
0.1369028,
-0.2809431,
-0.6291277,
-0.2691441,
0.2736249,
0.07175986,
0.3377644,
-0.005110749,
-0.09569734,
0.2939528,
0.01336143,
0.2065855,
0.2561035,
0.4144327,
0.1238779,
0.2284731,
-0.127634,
0.3125341,
0.2090012,
0.2861051,
0.4104047,
0.0697512,
-0.2344906,
0.0361... |
[Recurrent bronchopulmonary infections due to humoral immune deficiency]. | Between 1974 and 1978 11 patients were detected, in a pneumology department. They were classified as follows: stage I, with relatively benign bronchial infections; 5 patients were included in this group, all of them made uneventful recoveries, without sequellae; stage II was characterised by more severe infections, tha... | 229,544 | [
-0.04981543,
-0.5542758,
0.2185759,
-0.3512082,
0.05768432,
-0.2861889,
-0.2760091,
-0.258809,
-0.1960468,
0.001224639,
0.3027512,
0.06583997,
-0.1638622,
0.03893368,
-0.2530555,
-0.2421126,
-0.04215482,
-0.4059473,
0.1306876,
0.1862358,
0.414456,
-0.0903075,
0.0747347,
... |
[Clinical test in current psychopathologie (author's transl)]. | This clinical test, concerning the use of tiapride, was carried out for one year on 60 patients, with weekly or bi-mensual check-ups in a neuropsychiatric office, with no other associated medication capable of modifying either vigilance or humor. Tiapride, on top of its excellent tolerance (except for patients presenti... | 229,558 | [
-0.04828937,
0.1906032,
-0.1112361,
-0.1954698,
0.140991,
-0.4536575,
-0.3365423,
-0.1306207,
0.111808,
-0.1490393,
0.1882741,
0.3324327,
0.03581556,
-0.08529499,
-0.2931456,
0.07062754,
-0.3551692,
0.3534473,
0.01818893,
0.312753,
-0.1380098,
0.1140217,
0.02989284,
-0.... |
Traumatic hypopituitarism: anterior hypophyseal insufficiency from indirect cranial trauma. | We have reported a case of partial hypopituitarism involving deficient ACTH, LH, FSH, and growth hormone production and elevated prolactin. The hypopituitarism was caused by injury to the pituitary resulting from a parachute accident without direct craniocerebral trauma. The pathogenesis of this pituitary injury as eit... | 229,570 | [
-0.2783002,
0.09207538,
0.1074186,
-0.04907682,
-0.01642967,
-0.5762986,
-0.2353106,
-0.2010318,
0.2315401,
0.5112136,
0.1616013,
-0.1404185,
-0.3175575,
-0.04692088,
0.2210416,
-0.04194761,
-0.2939796,
-0.1226578,
-0.1319628,
-0.2741301,
0.02523061,
-0.1945952,
0.0090537... |
Estrone sulfate and dehydroepiandrosterone sulfate concentrations in normal subjects and men with cirrhosis. | Circulation levels of estrone sulfate (E1S) and dehydroepiandrosterone sulfate (DHAS) have been measured in plasma using a radioimmunoassay for estrone and dehydroepiandrosterone following extraction and hydrolysis of the sulfate. The mean +/- SE concentrations of E1S and DHAS in normal men were 458 +/- 25 pg/ml and 1.... | 229,590 | [
-0.3317114,
0.2724771,
-0.1254946,
-0.3163496,
-0.1494994,
-0.1978583,
0.1449111,
0.04861807,
0.04178108,
0.274062,
0.09463059,
0.1486711,
-0.003432088,
-0.09318289,
-0.3276445,
-0.1080597,
0.2725722,
0.1764554,
0.1083531,
0.02378758,
0.1108903,
0.2824213,
-0.1612332,
0... |
Effect of primary and recurrent cytomegalovirus infections upon graft and patient survival after renal transplantation. | One hundred sixty-four patients were prospectively studied for evidence of cytomegalovirus (CMV) infection after renal transplantation to determine the effect of primary and recurrent CMV infection on early graft and patient survival. Primary infections occurred in 62% (21 of 34) of pretransplant seronegative recipient... | 229,592 | [
-0.04012548,
-0.01874391,
-0.3012303,
-0.3057248,
0.07551762,
-0.1382791,
-0.2210709,
-0.006688165,
-0.1685461,
-0.1099077,
0.2227981,
0.3716818,
0.03110127,
0.0803846,
-0.2096858,
-0.3177053,
-0.02233745,
0.1992473,
0.08402728,
0.2791171,
0.06623267,
0.3325487,
-0.106690... |
[The effect of halothane anesthesia on the function of the adrenal cortex and some metabolites in the blood plasma of pigs not susceptible to malignant hyperthermia]. | The effects were investigated of a 25-minute inhalation of halothane with oxygen on three to four months old pigs of the Large White breed. Symptoms of malignant hyperthermia did not occur. The actual total anesthesia, which causes slight hypoproteinemia, hypoglycemia and hypocholesterolemia without significant changes... | 229,619 | [
-0.05175423,
-0.1483129,
0.2090129,
-0.4080817,
-0.02799587,
-0.3186541,
-0.2928081,
-0.05151853,
0.09789161,
0.03581648,
0.2109451,
-0.1092764,
0.2191125,
-0.1927066,
-0.1215522,
-0.2276108,
-0.2789628,
0.106321,
0.4393919,
0.1824474,
0.2520567,
-0.08041253,
-0.1140213,
... |
[Characteristics of thiamine diphosphate metabolism in the liver in acute hypobaric hypoxia]. | Rates of thiamin diphosphate accumulation in rat liver tissue and its subsequent depletion were decreased within the first hour after vitamin B1 administration into the animals with oxygen insufficiency. Hypoxia apparently inhibited simultaneously the processes of thiamin diphosphate biosynthesis and degradation, as a ... | 229,635 | [
-0.1225777,
-0.1406036,
-0.02047468,
-0.01240553,
0.2135986,
-0.2039374,
-0.06068896,
0.07585735,
-0.1553171,
-0.04612889,
0.1332125,
0.239124,
0.09551875,
-0.04255515,
-0.7499731,
-0.09191831,
-0.3965493,
0.2383669,
-0.2575483,
0.2653858,
0.2135847,
0.3000775,
-0.14347,
... |
[Nervous system pathology in uterine myomas]. | Clinico-physiological examinations of 218 patients with uterine myoma were carried out using the methods of electromyography and rheopgraphy. The following syndromes were revealed: a myopathic and a radiculoalgic ones; the syndrome of the external dermal femoral and the femorogenital nerves. The pathogenesis of these s... | 229,665 | [
0.1955064,
0.1778866,
-0.04863137,
-0.3059685,
-0.05799187,
-0.4039529,
-0.1277738,
-0.08716664,
0.01776659,
0.2364382,
0.16266,
-0.04382372,
0.1792827,
-0.2371335,
-0.2726432,
0.1384574,
-0.2590983,
0.1649153,
-0.1146115,
0.004118236,
0.4332431,
0.06820093,
-0.02972572,
... |
Recent concepts in the conservative treatment of intracranial tumours in children. | The role of radiotherapy for certain intracranial tumours, given either postoperatively or as the sole treatment in inoperable cases, is discussed, principally in relation to medulloblastoma, ependymoma, cerebral astrocytoma, brain-stem glioma and craniopharyngioma. Methods of increasing the response of gliomas to irra... | 229,698 | [
-0.1279411,
0.168165,
-0.1020208,
-0.3994804,
0.1227566,
-0.2610189,
-0.1655843,
-0.08935849,
-0.08044153,
0.436736,
0.08201674,
0.296621,
-0.1467586,
-0.2049339,
-0.2489582,
-0.1627262,
0.01262218,
0.3450158,
-0.2508608,
0.2489181,
0.1283192,
0.190831,
0.01867661,
-0.0... |
Storage and transport of cultures for Herpes simplex virus, type 2. | Tryptic soy broth and brain-heart infusion broth maintained herpes simplex virus within +/- 1 serial dilution of the original titer in all of 51 samples held for one to three days at 4 C. In contrast, holding temperatures of -20 C or 22 C resulted in losses of titer of 10(2) or more. Holding periods as long as five day... | 229,726 | [
-0.315186,
-0.2784556,
-0.4146093,
-0.07941625,
0.1928526,
-0.1455584,
-0.1258492,
0.202623,
-0.05206587,
-0.05214475,
0.1901002,
0.2228493,
0.03929648,
0.09514552,
-0.4094269,
-0.1130614,
0.07103375,
-0.1268461,
-0.2163042,
0.3871815,
0.1817106,
0.3349755,
0.02030499,
... |
Peripheral vascular disease following radiation therapy. | Radiation therapy is effective for the treatment of many malignant diseases. This fact is well documented. The existence of complications in any treatment form does not obviate its usefulness. An awareness of possible complications, however, makes our treatment program more realistic and causes us to be more aware of t... | 229,750 | [
-0.4021974,
0.09520279,
-0.1527083,
-0.1965374,
0.05433411,
-0.3663915,
-0.06929398,
-0.2344151,
0.2844038,
-0.01039281,
0.2479104,
-0.09459895,
-0.006854124,
-0.09091799,
-0.4827281,
-0.01428846,
-0.1604674,
-0.1455779,
-0.2494699,
0.1345136,
0.1500177,
0.4416681,
-0.084... |
Plasma and urine cyclic guanosine 3':5'-monophosphate in disseminated cancer. | Plasma and 24-h urinary adenosine 3':5'-monophosphate (cyclic AMP) and guanosine 3':5'-monophosphate (cyclic GMP) were measured by radioimmunoassay in 12 normal subjects, 33 patients with six types of non-neoplastic disease (cholelithiasis, peptic ulcer, coronary heart disease, hypertension, regional ileitis, and cirrh... | 229,752 | [
-0.4195179,
-0.1757405,
-0.3983059,
-0.5791445,
0.193322,
-0.2433906,
-0.1608522,
0.06169448,
-0.2164689,
0.258568,
0.09897856,
0.06842742,
0.006724597,
0.1095912,
-0.3415535,
0.03308684,
-0.004017932,
0.166662,
-0.03747244,
-0.179729,
0.5900716,
-0.1774966,
-0.1813702,
... |
Cyclic adenosine 3', 5' monophosphate: a possible indicator of premalignant changes in the large bowel. | Cyclic adenosine 3', 5' monophosphate (cyclic-AMP) has been estimated in mucosal biopsy samples removed from the descending colon and rectum at endoscopy to investigate the possibility of using this substance for monitoring pre-malignant changes in the large bowel. Four groups of patients have been studied: those with ... | 229,758 | [
-0.2710311,
-0.1324592,
-0.13568,
-0.2960669,
0.05840911,
-0.3634836,
0.08533542,
0.2293804,
0.2531435,
0.07814581,
0.101741,
-0.04752362,
0.1248865,
0.001963055,
-0.4948622,
0.1056709,
-0.4406739,
0.07358376,
0.2034602,
-0.04737138,
0.4491108,
-0.02513986,
-0.1855305,
... |
Bioaccumulation and depuration of enteroviruses by the soft-shelled clam, Mya arenaria. | Low levels of feces-associated natural virus, simulating virus numbers estimated to exist in moderately polluted shellfish-growing waters, were used to evaluate the effectiveness of depuration as a virus depletion procedure in soft-shell clams. Depuration effectiveness depended upon the numbers of virus bioaccumulated ... | 229,766 | [
-0.2561801,
-0.1808977,
0.1880167,
0.04010459,
-0.1961697,
-0.02688442,
-0.3065008,
0.2027619,
-0.01390479,
-0.2111267,
0.137795,
-0.1094557,
0.03655612,
-0.1487319,
-0.1138138,
-0.009039221,
-0.4911507,
-0.04724701,
0.4672861,
0.1499974,
0.0562665,
0.2669611,
-0.2622241,... |
Early changes in the chemical composition of the rat lung after silica administration. | A group of 200 g male Sprague-Dawley rats was injected with 75 mg of quartz (less than 5 mu particle size) and changes in lung DNA, noncollagenous protein, total lipids, and collagen were studied after 6, 24, 72, 96, and 144 hr. Another group of rats received 10, 30, 59, and 75 mg quartz and the above lung analysis was... | 229,775 | [
-0.03940149,
0.2118504,
-0.2395597,
-0.07870351,
0.07244289,
-0.1419015,
-0.1892738,
-0.002406509,
0.1066964,
0.100663,
0.1999321,
-0.2381715,
-0.1579593,
-0.1258534,
-0.3995424,
0.1995095,
0.1092206,
-0.009198568,
0.1313292,
0.1967869,
-0.09748068,
0.4522951,
-0.1348404,... |
Assembly of viral structural proteins in cells infected with a temperature-sensitive mutant derived from an HVJ (Sendai virus) carrier culture. Brief report. | The processing of virus polypeptides synthesized in cells infected with HVJ (haemagglutinating virus of Japan--the Sendai strain of parainfluenza 1 virus) was studied. Maturation of a temperature-sensitive (ts) mutant (HVJ-pB) derived from an HVJ carrier culture was inhibited at 38 degrees C incubation. A considerable ... | 229,791 | [
-0.1454965,
-0.4906493,
-0.1041758,
-0.1626824,
0.245218,
-0.1239943,
-0.06944339,
0.07472993,
0.2018815,
0.05468538,
0.1871881,
-0.1060198,
-0.09137858,
-0.07076713,
-0.3255363,
-0.08862504,
-0.1871493,
0.0121341,
-0.0218001,
0.1709572,
0.4840947,
0.08072556,
-0.2393932,... |
Marked increase in high density lipoproteins in mountaineers. | Apoprotein-AI concentrations were measured in whole blood in 13 male mountaineers before, during and after a strenuous climb of 8 weeks' duration. The AI concentration almost doubled in 3 weeks and remained elevated at that level for the full period of the climb. This study demonstrates the rapid rate at which high den... | 229,872 | [
-0.06538574,
0.04059831,
-0.1949714,
-0.007886808,
-0.005712923,
-0.03036065,
-0.4431816,
0.2908774,
0.04990669,
-0.1303224,
-0.01366386,
0.4932557,
0.2200609,
-0.1344328,
-0.1493843,
-0.140273,
-0.3846908,
-0.0467919,
-0.08221882,
0.3075933,
-0.02936011,
0.2027967,
-0.24... |
Fibrinogen and low density lipoprotein in the development of cerebral atherosclerosis. | Cerebral arteries from 65 human subjects were examined by immunofluorescence, using antisera against human fibrinogen and low density lipoprotein (LDL). Deposition of fibrinogen and LDL was most frequent at the bifurcation of the middle cerebral arteries and least in the basilar arteries in all age groups. In general, ... | 229,873 | [
0.06802073,
0.3734899,
0.1884033,
0.02854765,
0.09402221,
-0.3281579,
0.2201682,
-0.01000281,
-0.1144781,
0.3606603,
0.1344163,
-0.09741756,
0.1438818,
0.02525407,
-0.01498744,
-0.1843153,
-0.2525907,
0.2353482,
-0.1462668,
0.5907083,
0.03082166,
0.1763899,
0.01458577,
... |
[Method for isolation of enteroviruses from edible mollusca]. | A method for recovery of Poliovirus from experimentally inoculated mussels has been evaluated. The method, based on adsorption-elution-acid precipitation of virus particles, allows a recovery of more than 93% of the added virus. | 229,885 | [
-0.2709036,
-0.2540437,
-0.07891676,
-0.183449,
0.006806608,
-0.1733101,
-0.3513383,
0.1754779,
-0.07625777,
-0.08831279,
-0.009400673,
0.1344602,
0.1166828,
-0.3597418,
-0.503759,
-0.1510356,
-0.597212,
0.2081954,
-0.117322,
0.5036018,
0.3112435,
-0.04902028,
-0.2044414,... |
[Modifications of liver content of cyclic nucleotides in the rat poisoned with white phosphorus]. | In rat liver following white phorphorus poisoning a biphasic increase in cyclic AMP concentration was observed. After a lag period of 1 hour the cyclic AMP content rose to a first peak at 4 hours and to a second peak at 12 hours of intoxication. The cyclic AMP level fell to normal after 24 hours, by which time the cycl... | 229,887 | [
-0.2296205,
-0.1576694,
-0.2118861,
-0.1325491,
0.1287771,
-0.4072483,
-0.1637422,
0.1197117,
0.09927197,
0.2141043,
-0.0362737,
0.1400743,
-0.2076855,
0.2539459,
-0.5950308,
-0.2046569,
-0.2578986,
0.1260591,
0.2912664,
0.4323421,
0.620181,
0.1034753,
-0.2509235,
0.110... |
Covalent structure of collagen: amino acid sequence of alpha 2-CB5 of chick skin collagen containing the animal collagenase cleavage site. | The amino acid sequence of the 112 residues from the amino terminus of alpha 2-CB5 from chick skin collagen was determined by automated sequential degradation of intact alpha 2-CB5 and several chymotryptic and tryptic peptides. This segment of the peptide includes the site of the action of animal collagenases. As compa... | 229,892 | [
0.1538274,
0.05200102,
-0.3799163,
-0.00532678,
-0.04377522,
-0.159432,
-0.03049598,
0.1385552,
0.3680802,
0.1613564,
0.1779251,
0.1872041,
-0.01688544,
-0.02667144,
-0.2693886,
-0.1846253,
-0.5557429,
0.1217781,
-0.1414062,
0.1166816,
0.5770756,
0.4746004,
-0.1150789,
... |
Inhibition of adenylate kinase by P1-(lin-benzo-5'-adenosyl)-P4-(5'-adenosyl) tetraphosphate and P1-(lin-benzo-5'-adenosyl)-P5-(5'-adenosyl pentaphosphate. | P1-(lin-Benzo-5'-adenosyl)-P5-(5'-adenosyl) penraphosphate and P1-(lin-benzo-5'-adenosyl)-P4-(5'-adenosyl) tetraphosphate have been synthesized from lin-benzoadenosine 5'-monophosphoromorpholidate and adenosine 5'-tetraphosphate and adenosine 5'-triphosphate. These mixed dinucleoside polyphosphates are potent inhibitor... | 229,895 | [
-0.06739642,
0.1575008,
-0.1292826,
-0.1218303,
0.0469247,
0.06150987,
0.1268868,
0.09956397,
-0.08075295,
-0.1850993,
0.07670386,
0.09070225,
0.03714322,
-0.02836474,
-0.8867486,
0.08372621,
-0.7482269,
0.212399,
0.08305478,
0.2998623,
0.7810347,
0.05095145,
-0.1352703,
... |
Denaturation of thermophilic ferricytochrome c-552 by acid, guanidine hydrochloride, and heat. | The denaturation of Thermus thermophilus cytochrome c-552 by acid, guanidine hydrochloride, and heat was studied by measuring the changes in absorption and circular dichroism. Cytochrome c-552 was remarkably resistant to acid; the pK of the transition from the low- to the high-spin form was roughly 0.3. The effect of g... | 229,899 | [
-0.2870735,
0.08824062,
-0.3590716,
0.06777697,
0.2534496,
0.1091989,
0.2223653,
-0.1904849,
-0.05571266,
0.285767,
0.04468837,
0.3333222,
-0.138354,
0.07595845,
-0.2588056,
-0.2146465,
-0.4849387,
0.07525047,
-0.2845322,
-0.02415574,
0.366255,
-0.001077004,
-0.157646,
... |
Glutamyl transfer ribonucleic acid synthetase of Escherichia coli. Study of the interactions with its substrates. | The binding of the various substrates to Escherichia coli glutamyl-tRNA synthetase has been investigated by using as experimental approaches the binding study under equilibrium conditions and the substrate-induced protection of the enzyme against its thermal inactivation. The results show that ATP and tRNAGlu bind to t... | 229,901 | [
0.001343169,
0.4171509,
-0.3292416,
0.03513922,
0.06028444,
-0.2097306,
0.01482153,
0.06184812,
0.003696946,
0.05775173,
0.08592288,
0.2677034,
0.06854194,
0.1389313,
-0.4787232,
0.2912991,
-0.433001,
0.1229787,
-0.1953709,
0.1996648,
0.7236465,
-0.08071865,
0.0007124089,... |
Interaction of cytochrome c with the phosphorprotein phosvitin. | Candida krusei cytochrome c forms a molecular complex with phosphorprotein phosvitin in weakly alkaline solution of low ionic strength. At most, about 22 molecules of cytochrome c bind to a phosvitin molecule. The complex at the binding ratio below about 11 (half of the maximum ratio) as a much higher binding strength.... | 229,914 | [
-0.05015092,
0.08311294,
-0.3701245,
0.07813946,
-0.03538803,
-0.03754525,
-0.1652238,
0.1195733,
0.2467703,
0.02713076,
-0.1571438,
0.09283733,
-0.1516363,
0.1011241,
-0.3106282,
-0.3016967,
-0.3331126,
0.1353149,
0.2799068,
0.01737204,
0.4082836,
-0.05209694,
0.1547755,... |
Diabetic impotence: studies of nocturnal erection during REM sleep. | Nocturnal erections were studied in 30 diabetic patients who complained of impotence and in 11 healthy volunteers. The maximum increase in penile circumference was measured by a penile strain-gauge and recorded on a portable tape-recorder; an external oculogram was recorded simultaneously to identify periods of rapid-e... | 229,944 | [
-0.04932827,
-0.1707343,
-0.1398501,
0.1313635,
-0.1553803,
-0.2678387,
-0.0801714,
-0.1361716,
0.2189932,
0.09918569,
0.01333242,
-0.6732367,
-0.0805241,
0.2246942,
-0.2687411,
0.05834907,
-0.5818294,
0.1908652,
0.2738443,
-0.2212962,
0.1020886,
0.04530363,
0.1822821,
... |
Distribution and metabolism of adrenocorticotropin in the rat. | The time course of plasma bioactive adrenocorticotropin (ACTH) concentrations measured following two rapid injections of the hormone at doses of 7.5 and 22.5 mU/100 g, iv, and one infusion over a period of 80 min at a rate of 1.3 mU/min per 100 g, to male Sprague-Dawley rats whose endogenous release of ACTH had been bl... | 229,948 | [
-0.1943927,
0.1630119,
-0.6245093,
-0.3081252,
0.1589,
-0.2240222,
-0.3102409,
0.2736204,
-0.003462326,
-0.1138877,
0.1321425,
0.02365018,
0.140623,
-0.05421606,
-0.4174697,
0.017241,
0.09869714,
0.1336631,
0.2183191,
0.1261568,
0.4072904,
0.3320647,
0.1764993,
-0.01665... |
Intrapulmonary metastases from bronchogenic carcinoma and their radiographic detection. | Autopsies on 102 patients dying with bronchogenic carcinoma over an 11-year period revealed that 37.3% had pulmonary metastases. Review of the pathological evidence in questionable cases supported the validity of the diagnosis. This rather high figure is paralleled by the findings of others quoted in the literature. Di... | 229,980 | [
-0.1095567,
-0.2371663,
-0.1779799,
-0.3051374,
0.01524542,
-0.1961735,
-0.279439,
-0.2002396,
-0.1282134,
0.01908254,
0.1211553,
0.1894705,
0.02039754,
-0.0136251,
-0.3018447,
-0.3343303,
-0.02865695,
0.3014025,
0.3273706,
0.07157539,
0.4499238,
0.3996016,
-0.1238397,
... |
[New data on the intervention of cyclic monophosphate in the cardiac automatogenous process]. | We present here some new holistic titrations related to the demonstration of the intervention of threshold endogenous values of cAMP as a trigger biochemical factor of heart automatogenic function. | 229,989 | [
-0.2840161,
0.1207271,
-0.207596,
0.06332567,
0.04789265,
-0.263054,
-0.2941554,
0.1217728,
0.3109654,
-0.07080823,
-0.138315,
-0.01808296,
0.145432,
-0.01116811,
-0.5360329,
0.2321764,
-0.7863973,
-0.1245266,
-0.3138889,
0.2351764,
0.3552085,
0.05574904,
-0.1398448,
0.... |
Effects of (Bu2)-cAMP and clomiphene on serum concentrations of several proteins and hormones in gonadectomized monkeys. | Sixteen mumol kg-1 of dibutyryl cyclic adenosine 3',5'-monophosphate [(Bu)2cAMP] given intramuscularly to gonadectomized green monkeys (Cercopithecus aetheops sabeus) for two-week periods, produced a significant elevation in the serum concentrations of thyroxine-binding globulin (TBG), fibrinogen, and haptoglobin. No c... | 230,027 | [
-0.03445088,
0.03032401,
-0.5069513,
-0.3988961,
0.08360071,
-0.3837452,
-0.1113676,
0.01194679,
-0.04213545,
0.1521388,
-0.1298779,
0.1329571,
-0.05427773,
0.2255866,
-0.2311653,
-0.2538057,
-0.6906788,
-0.1248549,
0.4455802,
0.4322468,
-0.01796769,
0.2238812,
-0.3764127... |
Chemical and enzymatic characterization of the collagenase from the insect Hypoderma lineatum. | The collagenase from the larvae Hypoderma lineatum, with a molecular weight of 24 000 and isoelectric point of 4.1, was obtained in homogeneous form by ion-exchange chromatography. It is stoichiometrically inhibited by diisopropylfluorophosphate. On the other hand it is unaffected by ethylenediaminetetraacetate, p-chlo... | 230,030 | [
-0.04570603,
-0.05505772,
0.05361097,
-0.1707386,
-0.2775557,
-0.1986779,
-0.03414137,
0.3088515,
0.2514179,
0.3143821,
-0.03634256,
0.2796951,
0.06237355,
-0.2086165,
-0.3188254,
0.1717055,
-0.1404381,
0.01065474,
-0.1895809,
-0.04106943,
0.3275896,
0.2409532,
-0.2144776... |
Inactivation of gluconeogenic enzymes in glycolytic mutants of Saccharomyces cerevisiae. | Yeast mutants blocked at different steps of the glycolytic pathways have been used to study the inactivation of several gluconeogenic enzymes upon addition of sugars. While phosphorylation of the sugars appears a requisite for the inactivation of fructose 1,6-bisphosphatase and phosphoenol-pyruvate carboxykinase, malat... | 230,032 | [
-0.1183517,
0.04234283,
-0.1231027,
-0.0871569,
0.05955709,
-0.03751621,
0.1056685,
0.1902574,
0.007993387,
-0.03427807,
0.3976912,
0.01910295,
-0.1944608,
0.07147456,
-0.6635085,
0.1258916,
-0.09714033,
-0.01879165,
-0.06933758,
-0.001837269,
0.3724881,
0.1066947,
-0.056... |
Neurophysiological comparison of dendritic cable properties in adolescent, middle-aged, and senescent rats. | Relative dendritic atrophy has been reported in hippocampal granule cells of senescent (25 month) as compared to young (3 month) rats. An electrophysiological study of synaptic response waveform was un;ertaken to determine whether these anatomical changes have physiological correlates of functional significance to the ... | 230,053 | [
0.116589,
-0.04782862,
-0.1930597,
-0.3110882,
-0.04878168,
-0.7601022,
-0.1613788,
-0.1263923,
-0.1074144,
0.1073408,
-0.005938781,
0.05378868,
0.0983399,
-0.04329183,
-0.3898613,
0.1502425,
-0.2271987,
0.4043749,
0.08245987,
-0.1209405,
0.4859242,
0.223571,
0.2975185,
... |
Early changes of cyclic nucleotide levels in a mitogenic reaction in the rat mesentery. | By measuring simultaneously cAMP and cGMP we found a biphasic time course with regard to cGMP and the cGMP/cAMP ratio very early in a mitogenic reaction in vivo. This is a new finding. | 230,069 | [
-0.08179617,
-0.3668531,
-0.4096527,
-0.1498487,
0.2710781,
-0.1386219,
-0.07119512,
0.1081194,
0.08924273,
-0.003945753,
0.06340753,
0.00494246,
0.0869404,
0.04065973,
-0.7817751,
-0.03871962,
-0.3578056,
-0.05671903,
-0.2314616,
0.3232421,
0.4920346,
0.07836415,
0.16520... |
Sex-dependent action of prenatal fractionated X-irradiation in the mouse. Biochemical findings. | X-irradiation of pregnant NMRI-mice on gestational days 11-13 with 3 x 10.5 Gy increased postnatal mortality of the female offspring only. Weights, protein content and acetylcholinesterase, as well as Na,K-ATPase activities in the brains of all treated offspring, were changed. There were, however, no differences betwee... | 230,071 | [
-0.01486553,
-0.0989152,
-0.2318804,
-0.002546144,
0.008057873,
-0.4953255,
-0.05560301,
-0.4076708,
0.03424479,
0.2033036,
0.1480493,
0.3351884,
-0.002948205,
0.01762214,
-0.7777292,
-0.2535689,
-0.2089175,
0.1418576,
-0.2850981,
0.1150289,
0.2790561,
0.2479118,
-0.01358... |
Antibody to poliovirus in older children and young adults in Israel and the use of poliovaccines for the immunization of the seronegatives. | This report represents preliminary results of a more extensive study which is presently being carried out in Israel. The main aims of this study were twofold: (1) to carry out a survey of the state of immunity of children of various ages and of teenagers to the three poliovirus types and (2) to compare the antibody res... | 230,108 | [
-0.0993591,
-0.3501801,
-0.3046279,
-0.03196378,
-0.09769232,
-0.01543448,
-0.2970601,
0.08532756,
-0.08608087,
-0.02343122,
0.3927541,
0.3895026,
0.2739671,
-0.04724226,
-0.3854559,
-0.8630593,
-0.3098758,
-0.06086697,
0.06658213,
0.4691334,
0.4031538,
0.05655474,
-0.035... |
Antibody and cell-mediated immunity to a DNA free herpes simplex subunit vaccine. | The immunogenicity of a DNA free herpes simplex subunit vaccine was evaluated in chimpanzees and rabbits. The results clearly demonstrate that 1 injection of 3 micrograms/kg elicited antibodies as well as cell-mediated immunity in all the animals studied. These antibodies persisted for at least 6 months. Furthermore th... | 230,114 | [
-0.005926127,
-0.1362625,
-0.3113438,
-0.08573712,
-0.1368154,
-0.2871647,
-0.231046,
-0.01096573,
-0.03165068,
0.06444083,
0.257929,
-0.1498933,
0.224992,
-0.07824427,
-0.4375655,
-0.2545344,
-0.3504505,
0.2608967,
-0.0472876,
0.4668297,
0.3382774,
-0.07835336,
-0.027125... |
Fine structure of a glomus tumor of the tongue and expression of C type virus in its tumor cells. | A glomus tumor in the tongue of a 29-year-old Japanese male is presented. Ultrastructural examination demonstrated this tumor to be composed of the tumor cells having structural features in common with smooth muscle cells, and mast cells as the less frequent type cell. Moreover, a small number of C type virus particles... | 230,158 | [
-0.2959918,
0.05920117,
-0.02306532,
-0.1102808,
0.015088,
-0.07723182,
-0.189623,
0.0971917,
0.1100275,
0.2453738,
0.1240867,
-0.06779721,
-0.1679871,
-0.03599627,
-0.313593,
-0.05288628,
0.2390085,
0.1212695,
0.3655502,
0.07735459,
0.2790935,
0.05683717,
0.01657708,
0... |
Synthesis and inactivation of carbamyl phosphate synthetase isozymes of Bacillus subtilis during growth and sporulation. | Pyrimidine-repressible carbamyl phosphate synthetase P was synthesized in parallel with aspartate transcarbamylase during growth of Bacillus subtilis on glucose-nutrient broth. Both enzymes were inactivated at the end of exponential growth, but at different rates and by different mechanisms. Unlike the inactivation of ... | 230,177 | [
0.04938626,
-0.1806602,
0.06253491,
0.1109074,
-0.02608146,
-0.4279552,
-0.212818,
-0.09470313,
0.07518566,
0.2047448,
-0.04213013,
0.5124338,
-0.3484669,
0.5742208,
-0.3762881,
0.3952526,
-0.1300062,
-0.06791981,
-0.05497951,
0.3302803,
0.4780326,
0.06693899,
-0.1147875,... |
Isolation of temperature-sensitive pantothenate kinase mutants of Salmonella typhimurium and mapping of the coaA gene. | Temperature-sensitive pantothenate kinase mutants of Salmonella typhimurium LT2 were selected by using the excretion of pantothenate at the nonpermissive temperature as a screening method. Thermolability of the pathothenate kinase activity in extracts of the mutants was demonstrated. The mutations were mapped at min 89... | 230,178 | [
0.1407092,
-0.3219557,
0.1020249,
-0.2698739,
-0.2539825,
-0.107389,
-0.1257872,
-0.09935497,
0.001596523,
-0.1527247,
0.3944522,
0.2492994,
-0.04166739,
0.01541152,
-0.3389052,
-0.03383268,
-0.3840447,
-0.0781747,
0.2406909,
0.1983628,
0.5932322,
0.3405267,
-0.1708881,
... |
Biosynthesis of phospholipids in Bacillus megaterium. | Information on the biosynthesis of phospholipids in bacteria has been derived principally from the study of Escherichia coli and other gram-negative organisms. We have now carried out a detailed study of the pathways of phospholipid biosynthesis in the gram-positive organism Bacillus megarterium KM in relation to inves... | 230,180 | [
-0.05433753,
-0.2454252,
-0.3416325,
0.2226715,
-0.1244344,
-0.02326204,
-0.1737816,
0.07588883,
-0.1532096,
-0.1170609,
0.03189197,
0.2298255,
-0.0578348,
0.2547391,
-0.2611626,
-0.05266646,
-0.3280388,
0.06765195,
-0.3022045,
0.1731393,
0.6131303,
0.3956449,
-0.02166791... |
Cyclic nucleotide levels in rat embryo fibroblasts treated with tumor-promoting phorbol diester. | Intracellular concentrations of cyclic adenosine 3':5'-monophosphate (cyclic AMP) and cyclic guanosine 3':5'-monophosphate were measured in rat embryo fibroblasts stimulated to divide by either the addition of 12-0-tetradecanoyl phorbol-13-acetate (TPA) or a serum-supplemented medium change. Cyclic nucleotide levels we... | 230,210 | [
-0.2432929,
0.0612506,
-0.4291063,
-0.4347098,
0.4535259,
-0.2766524,
-0.2594707,
0.1078882,
0.1339293,
0.08054044,
-0.09376655,
-0.1908043,
-0.0906913,
0.1169922,
-0.4020011,
-0.1466492,
-0.4443631,
-0.09944027,
-0.1949973,
0.2277289,
0.4450309,
0.1827413,
-0.3013742,
... |
H-2 and non-H-2 determined strain variation in palatal shelf and tongue adenosine 3':5' cyclic monophosphate: a possible role in the etiology of steroid-induced cleft palate. | The concentration of cAMP was measured in palatal shelves and tongues of 14.5-day old foetuses, 14.5-day old foetuses from steroid treated mothers, and 15.5-day old foetuses from four inbred lines of mice which represent the four possible combinations of two H-2 alleles and two residual genetic backgrounds. The inciden... | 230,263 | [
-0.03500764,
-0.05569914,
-0.1519389,
-0.3601494,
0.5191112,
-0.1324232,
0.1053752,
0.08224338,
0.5009296,
0.001834639,
0.008570153,
0.006488397,
-0.2286427,
0.151625,
-0.1171406,
-0.2084741,
0.2032308,
-0.3155442,
-0.1927568,
0.3646435,
0.4451624,
0.2145047,
-0.3168929,
... |
Induction of simian virus 40-specific tumour rejection by the Ad2+ND2 hybrid virus. | Immunization of BALB/c mice with Ad2+ND2, a non-defective hybrid virus containing about half of the early region of simian virus 40 (SV40) DNA covalently integrated into the human adenovirus 2 (Ad2) genome, can confer protection against subsequent challenge by syngeneic SV40 tumour cells. Analysis of subcellular fracti... | 230,283 | [
-0.2716737,
-0.01524713,
-0.2126511,
-0.2219683,
0.1602254,
-0.07642892,
-0.1155866,
0.2631954,
0.3524379,
0.234536,
0.009750147,
0.008370237,
0.04206445,
-0.2216495,
-0.6736374,
-0.1133726,
-0.3620978,
0.02129942,
0.006391189,
0.1169618,
0.1051614,
0.1393113,
-0.1710705,... |
Modulation of herpes simplex virus replication in adenovirus transformed cells. | The ability of herpes simplex virus 1 to replicate in cells transformed by adenovirus type 5 is strongly dependent on the origin of the cells. Studies show that adenovirus transformed rat cells lose their permissiveness while cells of hamster or human origin retain their ability to replicate HSV although at a reduced l... | 230,284 | [
-0.2362495,
-0.09247161,
-0.3300088,
0.1312822,
0.1409849,
-0.1191785,
-0.05735504,
-0.08600534,
0.5148229,
0.1651061,
0.1373694,
-0.3278257,
0.03732273,
0.1386197,
-0.56354,
-0.1193763,
-0.3555596,
0.0594458,
0.004815332,
0.1639526,
0.05748853,
0.2613685,
-0.02461507,
... |
Latent cytomegalovirus infection of BALB/c mouse spleens detected by an explant culture technique. | Latent murine cytomegalovirus (MCMV) infection of BALB/c mouse spleens was studied using several methods including an explant tissue culture technique, co-cultivation on allogeneic and syngeneic cell cultures and nucleic acid hybridization. BALB/c mice experience latent infection which persists for at least 6 months an... | 230,295 | [
0.03509716,
-0.308436,
-0.07160351,
0.00308179,
0.2239407,
-0.1243583,
-0.4089859,
0.1952676,
0.2392149,
0.02415944,
-0.04714066,
0.04932752,
0.1331988,
0.06454197,
-0.63681,
-0.3353562,
-0.08697297,
-0.02484082,
-0.09264381,
0.3950644,
0.2886785,
-0.253713,
0.07530578,
... |
Possible point mutation sites in LSc, 2ab poliovirus RNA and a protein covalently linked to the 5'-terminus. | Poliovirus type I, vaccine strain (LSc, 2ab), which is a temperature- and actinomycin D-sensitive mutant derived from type I Mahoney strain, was grown in HeLa cells in the presence of 32P and a low concentration of actinomycin D. Seven and a half h p.i., genome 32P-RNA was recovered from the purified virion. Analysis o... | 230,298 | [
0.2585677,
-0.2126478,
-0.1850464,
0.0966225,
0.06001095,
-0.07748511,
-0.02297507,
0.009201303,
0.3804823,
-0.1647983,
0.1001073,
0.004628759,
-0.08929925,
-0.02403539,
-0.2966835,
0.01312881,
-0.3316771,
-0.1006391,
0.1297771,
0.4371094,
0.3919829,
0.2071672,
-0.249886,... |
Neurotoxicity of halogenated hydroxyquinolines: clinical analysis of cases reported outside Japan. | An analysis is presented of 220 cases of possible neurotoxic reactions to halogenated hydroxyquinolines reported from outside Japan. In 80 cases insufficient information was available for adequate comment and in 29 a relationship to the administration of clioquinol could be excluded. Of the remainder, a relationship to... | 230,316 | [
-0.3156009,
-0.149778,
0.181703,
-0.2790183,
0.1289341,
-0.2010498,
-0.1243118,
-0.03611013,
0.1299039,
-0.1401034,
0.2465774,
-0.06990461,
0.2583018,
0.3173073,
-0.05116821,
-0.2633836,
-0.2133337,
0.444227,
0.08360478,
0.173514,
0.07285829,
0.2971907,
-0.16931,
-0.131... |
Activation by sanguinarine of active sodium efflux from frog skeletal muscle in the presence of ouabain. | 1. Applied to intact Na-rich muscle cells, sanguinarine causes an increased 22Na efflux in the presence or absence of extracellular K+ or of ouabain. 2. The increased 22Na efflux does not represent Na:Na exchange as indicated by the fact that it is not associated with an increase in one-way isotopic Na influx nor is it... | 230,333 | [
-0.4452192,
0.1138539,
-0.1701467,
-0.01663039,
0.1015381,
-0.06512453,
-0.2375483,
-0.01892161,
0.006455759,
-0.05069558,
0.2177103,
0.1771741,
0.2054299,
-0.3693653,
-0.3105072,
-0.1321012,
-0.3474651,
0.09864519,
-0.02189011,
0.0006754097,
0.6031723,
-0.1237676,
-0.114... |
Metabolic effects of oral contraceptives containing 30 micrograms and 50 micrograms of oestrogen. | In Study A, biochemical data from 17 women who were not taking oral contraceptives were compared with those from women taking preparations which contained either 30 microgram of ethinyl oestradiol and 150 microgram of D-norgestrel (18 women) or 50 microgram of ethinyl oestradiol and 250 microgram of D-norgestrel (nine ... | 230,411 | [
-0.01828478,
0.3489965,
-0.1712044,
-0.192759,
0.02645395,
-0.09916562,
-0.05919377,
0.138718,
0.05841656,
0.1231013,
0.1325457,
0.4401202,
0.2772876,
-0.01030789,
-0.3776008,
0.003159938,
0.001295558,
-0.09248418,
-0.08456647,
0.4819492,
0.2522528,
0.3685661,
0.01795584,... |
Interaction of diazepam with synaptic transmission in the in vitro rat hippocampus. | Diazepam (5 x 10(-8) - 10(-6) M) was found to augment recurrent inhibition of pyramidal neuron firing in a dose-dependent manner in rat hippocampal slices. To determine possible loci of this effect, diazepam was locally administered by pressure ejection from a micropipette, while recording action potentials from single... | 230,418 | [
0.01194114,
0.07101655,
0.004422375,
-0.1544387,
0.05588548,
-0.5045277,
-0.3023063,
-0.3031398,
-0.03302143,
-0.248875,
0.07628598,
0.2320505,
0.02733558,
0.2804953,
-0.02032185,
-0.1253604,
-0.3142045,
0.1721786,
0.03806963,
0.1285579,
0.0378979,
-0.08622795,
0.3012362,... |
[Familial Hodgkin's disease: a case report and review of the literature]. | In a family of five sisters four developed malignant lymphomas. A case report is given together with a literature survey of familial Hodgkin's disease. The observations fit the hypothesis that for the development of Hodgkin's disease two requirements must be met: a genetically determined susceptibility as well as some ... | 230,435 | [
-0.2531811,
-0.3207328,
0.126866,
-0.1724646,
0.1503137,
-0.2866887,
-0.248639,
-0.2777103,
-0.1730608,
0.2042537,
0.268036,
0.3345364,
0.1385633,
0.1829755,
-0.4027418,
-0.3215697,
-0.2638102,
0.1890607,
0.1769567,
0.1362171,
0.3113695,
0.0962569,
0.01721138,
0.2264551... |
Cranial nerve damage in patients after alpha (heavy)-particle radiation to the pituitary. | The records of 161 patients were reviewed to determine if radiation damage had occurred following cranial irradiation. All of these patients had received alpha-particle radiation to their pituitary glands during the period when this form of therapy was given for diabetic retinopathy. Extraocular muscle palsy developed ... | 230,438 | [
-0.1830661,
-0.1641692,
-0.2942167,
-0.006780442,
0.004622562,
-0.198384,
-0.1247267,
-0.06687825,
0.3686331,
0.2100271,
0.05660536,
-0.3855078,
-0.03474888,
-0.09218924,
-0.02755298,
-0.06806678,
-0.02752925,
0.1496332,
0.3059744,
-0.03831491,
0.06995386,
0.1634727,
0.33... |
Interaction of physalaemin, substance P, and eledoisin with specific membrane receptors on pancreatic acinar cells. | We have prepared 125I-labeled physalaemin and have examined the kinetics, stoichiometry, and chemical specificity with which the labeled peptide binds to dispersed acini from guinea pig pancreas. Binding of 125I-labeled physalaemin was saturable, temperature-dependent, and reversible and reflected interaction of the la... | 230,488 | [
-0.02534668,
-0.1819573,
-0.234276,
0.2245,
-0.05938102,
-0.03002796,
-0.324363,
-0.1047731,
0.1586778,
0.3237453,
0.05410614,
-0.005934048,
0.1456879,
-0.07983845,
-0.2270717,
-0.08070756,
-0.5840655,
-0.02621279,
0.2403102,
0.08424591,
0.06529506,
-0.1090178,
-0.0104619... |
Metal-coordinating substrate analogs as inhibitors of metalloenzymes. | A group of active-site metal coordinating inhibitors of zinc proteases (carboxypeptidase A, thermolysin, Bacillus cereus neutral protease, and angiotensin-converting enzyme) have been synthesized and their properties investigated. Their general structures are R-SH and R-NH-PO2(O phi)H, where-S- or -O- serve as metal li... | 230,502 | [
-0.2441862,
0.02582769,
-0.1768689,
0.07246454,
-0.2639896,
0.04596477,
-0.09440026,
0.1827224,
0.3334236,
0.1049039,
0.09218749,
0.4057659,
0.01738367,
-0.3055029,
-0.8514771,
0.3218344,
-0.2376689,
0.2027948,
0.2101271,
0.2425969,
0.1647788,
-0.03899116,
-0.1203821,
0... |
Microenvironmental influences on the in vivo behavior of neoplastic lymphocytes. | A transplantable hamster lymphocytic neoplasma of probable monoclonal derivation, induced by the oncogenic DNA simian virus 40, has been adapted to grow in the allogeneic host either as leukemia (characterized by dissemination and poor prognosis) or as lymphoma (characterized by localization and favorable prognosis) [D... | 230,511 | [
0.06940083,
-0.2794688,
-0.0001792016,
-0.06360821,
-0.1326227,
-0.256663,
-0.02123157,
0.04301869,
-0.01963088,
0.007245481,
0.08187228,
0.02261491,
0.1061201,
-0.08952192,
-0.4150344,
-0.09537439,
-0.2626978,
-0.2394496,
0.1017365,
0.237918,
0.1352074,
0.239732,
-0.1197... |
Evidence for separate PGD2 and PGF2 alpha receptors in the canine mesenteric vascular bed. | Potential interactions between PGD2 and PGF2 alpha in the mesenteric and renal vascular beds were investigated in the anesthetized dog. Regional blood flows were measured with electromagnetic flow probes. PGD2, PGF2 alpha and Norepinephrine (NE) were injected as a bolus directly into the appropriate artery, and respons... | 230,544 | [
-0.1305262,
0.191748,
-0.3795059,
-0.261172,
0.5017588,
-0.2786542,
0.04110646,
-0.100632,
-0.2579789,
-0.1714835,
0.1911096,
-0.08978558,
-0.05300296,
-0.2152032,
-0.7880434,
-0.2339645,
-0.4015186,
0.03972915,
0.09694681,
0.1483465,
0.1918224,
0.1712984,
-0.09719548,
... |
[Sleep polygraphy with recording of intracranial pressure and measure of cerebral blood volume in hydrocephalic infants (author's transl)]. | This study was carried with the intention of explaining the causes of modifications in intracranial pressure (ICP) during paradoxical sleep (PS) in normal and hydrocephalic infants, and establishing relationships between these modifications and cerebral blood volume (CBV). All tests (conventional sleep polygraphy, ICP ... | 230,550 | [
0.05429544,
-0.1250796,
-0.2942643,
-0.149878,
0.07039212,
-0.4522788,
-0.2550437,
-0.2122818,
-0.240688,
0.2138163,
0.2644878,
0.3682441,
-0.5313765,
-0.09836524,
-0.3953611,
-0.3619421,
-0.3160749,
0.1139063,
-0.1027739,
0.1446182,
0.1557572,
-0.3699098,
-0.06595169,
... |
Establishment of anti-TNP antibody-producing human lymphoid lines by preselection for hapten binding followed by EBV transformation. | Human lymphoblastoid cell lines that produce specific antibody against the hapten trinitrophenyl (TNP) have been established by selecting TNP-binding human B lymphocytes by TNP-rosetting and Ficoll-Isopaque separation, followed by Epstein-Barr virus (EBV) immortalization. Derived lines secreted polyclonal anti-TNP anti... | 230,581 | [
-0.1661029,
-0.1486773,
-0.1753753,
-0.1504343,
0.1146482,
-0.2139625,
-0.03487512,
0.3378723,
0.2097322,
0.4558288,
0.2893026,
0.181487,
0.03564699,
-0.1079796,
-0.5024403,
-0.07694885,
-0.3937425,
0.2034708,
0.08540955,
0.2302342,
0.2135832,
0.03184465,
-0.02217662,
-... |
[Transient osteoporosis of the hip in pregnancy. Report of three cases (author's transl)]. | Three cases of transient osteoporosis of the hip in pregnant women are reported, and compared with 13 similar observations, published in world literature. The disease occurs during second half of pregnancy, revealed byrnotion hip pain, and slight limitation of mobility. On radiography, the femoral head and acetabulum a... | 230,587 | [
0.1017294,
0.1442166,
0.139345,
-0.05677161,
-0.01513131,
-0.3958181,
-0.1152604,
-0.04466197,
0.1317663,
0.1076926,
-0.02864295,
-0.1226601,
-0.1341744,
-0.1748123,
-0.3505449,
-0.5038351,
-0.1412252,
0.4041575,
-0.1168139,
0.09011519,
0.401644,
0.254836,
-0.1301514,
0... |
[Muscular metastases. A case report (author's transl)]. | Muscular metastases are exceptionally reported. The authors present a case of crural neuralgia in relation with a localisation in the psoas iliacus of a gastric carcinoma. A review of literature defines the rarity of this facts (156 cases) the etiology (carcinome more often) and the explication who is still obscur. | 230,594 | [
-0.07367696,
-0.1377655,
-0.213109,
-0.2140732,
0.00668351,
-0.1210647,
-0.3380249,
0.07006297,
0.02796435,
-0.0008936251,
0.1613857,
0.01667659,
0.3178798,
-0.3163018,
-0.2824973,
0.0299894,
-0.1828615,
0.0226406,
0.1586563,
0.1872008,
0.1988069,
-0.2439424,
-0.1064161,
... |
[Anterior perinephritic phlegmon (author's transl)]. | A case is reported of an unsuspected anterior perinephritic phlegmon which had caused peritonitis of pyelonephritic origin thought to be due to a cholecystitis. The lesion was discovered during laparotomy and intravenous urography at operation demonstrated the condition of the underlying kidney and determined the thera... | 230,596 | [
-0.08161656,
-0.04394723,
-0.3088609,
0.02691455,
0.09550131,
-0.1864702,
-0.478377,
-0.1876568,
-0.1615017,
-0.04827163,
0.09062517,
0.04270956,
0.07002629,
-0.1288194,
-0.3379449,
-0.3143558,
-0.2446396,
0.262071,
0.005085127,
0.01985462,
0.4449806,
-0.05875665,
-0.0766... |
Studies on the tissue-disposition and fate of N-[14C]ethyl-N-nitrosourea in mice. | The tissue-disposition and fate of N-[14C]ethyl-N-nitrosourea has been studied in mice. A large part of the injected N-[14C]ethyl-N-nitrosourea radioactivity was found to be exhaled as 14CO2. Whole-body autoradiography showed evenly distributed radioactivity in most tissues shortly after the administration of N-[14C]et... | 230,616 | [
-0.2817837,
0.08755538,
-0.1495248,
-0.08436012,
0.4019727,
-0.4186015,
-0.1980871,
0.06273838,
-0.08039369,
0.1212237,
-0.006421708,
-0.3118155,
0.4747612,
0.2442391,
-0.73004,
0.04167773,
-0.2674871,
0.1630558,
-0.01804944,
0.4820596,
0.09707887,
0.3608071,
-0.04223945,... |
Effect of phenobarbital on cerebral energy state and metabolism. Enzymatic activities. | The changes induced by phenobarbital in cerebral enzymatic activities of the Krebs' cycle (citrate synthase, malate dehydrogenase) and electron transfer chain (total NADH-cytochrome c reductase and cytochrome oxidase) were studied. In addition, the activity of lactate dehydrogenase of acetylcholine esterase and of glut... | 230,618 | [
0.1250984,
0.2047363,
0.113547,
0.1743192,
-0.121665,
-0.4258429,
-0.06127674,
-0.1233078,
-0.3999545,
0.1022686,
-0.05453056,
0.348482,
-0.1420918,
0.2747917,
-0.846608,
0.2611772,
-0.5288309,
0.2420387,
0.0934974,
0.2826096,
-0.039123,
0.2659112,
0.1590511,
-0.0089591... |
Detection of hepatitis B surface antigen in fixed tissues of patients with cirrhosis and hepatoma. | HBsAg has been sought by light microscopy in liver specimens from patients with cirrhosis (79 cases) and hepatoma (99 cases). The study was carried out on fixed material using orcein staining, immunoperoxidase technique and indirect immunofluorescence. HBsAg was detected in the serum by radio-immunoassay (RIA) using Au... | 230,634 | [
0.0797838,
-0.3208553,
0.0242916,
0.1552234,
-0.1351624,
-0.1613618,
-0.2801228,
-0.1069469,
0.319124,
0.2469842,
-0.1862397,
0.03170824,
0.001502834,
0.1562412,
-0.3614616,
-0.3799085,
-0.04498826,
-0.07784163,
-0.1161269,
0.004403186,
0.07868734,
-0.05485055,
-0.2323597... |
[Viral interaction with stimulated and nonstimulated human tonsil cells]. | Interferon induction and the course of infection with paramyxovirus (Newcastle disease virus) and alphaviruses (Venezuelan equine encephalomyelitis, Sindbis, Semliki forest viruses) in human tonsillar cell cultures were studied in comparison with continuous Burkitt lymphoma, Raji, and Nawalva cells. The virus inducers ... | 230,646 | [
-0.3276047,
-0.2693999,
0.04180442,
-0.3133887,
0.5008569,
-0.4939573,
-0.3884667,
-0.06838346,
-0.2346819,
0.1931488,
0.1357738,
-0.007614663,
0.1064031,
-0.138612,
-0.5345697,
-0.3131582,
-0.3391365,
0.07619505,
-0.5841713,
0.05486403,
0.4598723,
-0.01594391,
0.031712,
... |
Production of antiviral and migration inhibitory activities in the peritoneum of mice after inoculation with allogenic Ehrlich ascites tumor cells. | Peritoneal inoculation of Ehrlich ascites cells into mice stimulates the appearance of migration inhibitory factor (MIF) not only in the peritoneum but also in the circulation of mice. Whereas the MIF-activity in the peritoneum reached maximum at 6 days and disappeared within 17 days, the MIF-activity of sera reached m... | 230,674 | [
-0.2874287,
0.1444144,
-0.210191,
-0.4944899,
0.3733449,
0.003126689,
-0.1270062,
0.09193369,
-0.02829456,
-0.04847618,
-0.2546986,
0.1085771,
0.1609327,
0.05972933,
-0.4074361,
0.1779214,
-0.1399228,
-0.05283577,
-0.199772,
0.4891235,
-0.07151607,
-0.1632737,
-0.413123,
... |
Cytomorphology of carcinoid tumors. | This report is based on a review and study of carcinoid tumors as seen in smears prepared from exfoliative or aspiration smears. During a period of eight years (1970 to 1978), 236 cytologic specimens were examined from 64 patients treated for carcinoid tumors at Memorial Hospital. Thirty-eight cytologic specimens from ... | 230,682 | [
-0.2469439,
-0.320143,
-0.3519373,
-0.5263969,
-0.178179,
-0.3644325,
-0.2551779,
-0.1063082,
0.2347209,
0.400811,
0.2462356,
0.2792047,
-0.1721889,
-0.04274895,
-0.1613982,
0.07456914,
-0.03658718,
0.006380837,
0.1642447,
-0.01861873,
0.56644,
0.04175556,
0.008275713,
... |
An immunodiffusion test for detection of bovine viral diarrhea virus antibodies in bovine serum. | An immunodiffusion test (IDT) was developed for detecting bovine viral diarrhea virus antibodies in bovine serum. The antigen utilized in the IDT was prepared from bovine viral diarrhea virus-infected monolayer cultures. Results of the IDT were obtained within 48 hours and correlated with the virus-neutralization test. | 230,770 | [
-0.334715,
-0.2004922,
0.04688178,
0.1173165,
0.1024938,
0.03090825,
-0.1372706,
0.3503406,
0.0946223,
-0.2447328,
0.2547848,
0.184857,
-0.1586001,
0.2190932,
-0.2934144,
-0.2100575,
-0.5794129,
0.2139014,
-0.4096989,
0.00175014,
0.1020494,
-0.004810669,
0.0650631,
-0.2... |
Familial subacute necrotizing encephalomyelopathy of the adult form (adult Leigh syndrome). | A family--mother and 2 sons--with a heredodegenerative neurological disease is described. The disease started with bilateral optic atrophy, central scotoma, and color blindness during the second decade. This was followed by a quiescent period until additional neurological symptoms appeared, around the age of 50 years i... | 230,781 | [
0.006708255,
0.01209524,
0.1082548,
-0.235816,
-0.004087166,
-0.3324502,
-0.1827,
-0.6473335,
0.001832756,
0.01996897,
0.006819341,
0.142826,
0.03160517,
0.19844,
-0.1592677,
-0.1475641,
-0.3893423,
0.07070453,
0.3000985,
-0.03369994,
0.2473651,
0.3286156,
-0.001760783,
... |
Structural and compositional changes associated with chlorine inactivation of polioviruses. | Chlorine inactivation of polioviruses resulted in the loss of viral ribonucleic acid, converting the viruses from 156S particles to 80S particles. However, it was found that virus inactivation occurred before the ribonucleic acid was released from the virions. Extraction of ribonucleic acid from partially inactivated v... | 230,785 | [
-0.1862435,
0.3788041,
-0.140897,
-0.1738968,
0.2766534,
-0.2655252,
-0.07675043,
-0.07562343,
0.3008767,
0.01703801,
0.03469934,
0.4854159,
-0.0802164,
0.03379235,
0.05999822,
0.09864635,
-0.1443053,
-0.1705867,
-0.08085108,
0.273143,
0.08121537,
0.3088526,
-0.2238182,
... |
Adenylyl cyclase deficient cr-1 (Crisp) mutant of Neurospora crassa: cyclic AMP-dependent nutritional deficiencies. | The inability to synthesize cyclic AMP drastically affects the nutritional metabolism of Neurospora crassa. The adenylyl cyclase-less mutant cr-1 (crisp) did not utilize several carbon sources, including glycerol, mannitol, arabinose, and casaminoacids. However, in glucose or acetate it grew as well as the wild type. T... | 230,797 | [
-0.02905201,
-0.05284477,
-0.1083046,
-0.3811005,
-0.02655206,
-0.05838016,
-0.2665979,
0.04095264,
0.4008135,
0.03708564,
0.1579267,
0.0767052,
-0.1408887,
0.156008,
-0.2810931,
0.03637005,
-0.5947068,
-0.2990386,
-0.06663808,
-0.1028781,
0.2706901,
0.09504489,
-0.122405... |
Adult rhabdomyoma of the larynx. | A case of rhabdomyoma of the larynx in a 76-year-old woman patient is reported. The tumor was localized on the left vocal cord. This case is, so far described, the seventh one of adult rhadbomyoma of the larynx. The differential histological and histochemical diagnosis with granular cell myoblastoma is discussed and ta... | 230,799 | [
-0.216219,
0.07364484,
-0.3649104,
-0.1043582,
0.01753241,
-0.1488513,
-0.2159151,
-0.0979943,
-0.03476941,
0.2608773,
0.3083216,
0.3298659,
0.02420021,
-0.1729413,
-0.02313325,
-0.1073866,
0.03205142,
0.3047059,
-0.04338821,
-0.2050441,
0.4805079,
0.2280593,
0.05362431,
... |
Excitability and NADH fluorescence of spontaneously active portal veins in relation to glucose withdrawal. | The effect of glucose withdrawal upon mechanical activity and the redox level of pyridine nucleotides and flavoproteins was investigated in isolated rat portal veins under aerobic conditions. A decrease of extracellular glucose concentration correlated with contractile activity. During acetylcholine-induced tetanic con... | 230,870 | [
0.1422484,
-0.01184501,
-0.5009789,
0.09719919,
0.1435427,
-0.4478199,
0.1235101,
-0.1286858,
-0.1578165,
-0.0882974,
0.1676922,
-0.1513952,
-0.01543089,
-0.3800408,
-0.4830513,
-0.0928145,
-0.8682184,
0.1269121,
-0.252724,
0.1540201,
0.29078,
0.006789754,
0.2239136,
0.... |
Treatment of small cell bronchogenic carcinoma with VM-26. | VM-26 is active in small cell bronchogenic carcinoma even in patients resistant to previous chemotherapy. The overall response rate was 28%, with a response rate of 29% in patients resistant to previous chemotherapy. This response rate is similar to that obtained with other single agents including Adriamycin, vincristi... | 230,897 | [
-0.2196303,
-0.2355877,
-0.1505137,
-0.5677125,
0.184162,
-0.1699178,
-0.430146,
-0.1053494,
0.1878738,
0.05341003,
0.255344,
0.08268699,
-0.004338999,
0.2794154,
0.004353565,
-0.1544173,
-0.3122318,
0.421378,
0.1304665,
0.1575333,
0.3558309,
0.0267907,
-0.02944312,
-0.... |
Neurons of the rat hypothalamus reactive with antisera against endorphins, ACTH, MSH and beta-LPH. | In rat brains intraventricularly injected with colchicine, the same discrete neurons of the arcuate and ventromedial nuclei can be stained with antisera against alpha- and beta-endorphins, (1-24)ACTH, (17-39)ACTH, alpha- and beta-MSH, and beta-LPH, as demonstrated by comparative studies in consecutive serial sections. ... | 230,904 | [
-0.01036431,
-0.01440277,
-0.1606476,
-0.03145215,
0.04632331,
-0.4405797,
-0.3994099,
-0.01601186,
0.02166856,
0.1743222,
-0.01369361,
0.2733271,
0.4567256,
-0.09610421,
-0.3720203,
-0.2257409,
-0.3710457,
0.2891719,
0.1154859,
0.3757314,
0.2303053,
0.197149,
-0.1470337,... |
Active and inactive renin in normal human plasma. Comparison between acid activation and cryoactivation. | Inactive renin in human plasma is converted to active renin in vitro by acid activation or by cryoactivation. Renin activity was measured at pH 5.5 and renin concentration at pH 7.4. The plasma renin activity before and after cryo-treatment is termed active (APRA) and total (TPRA) plasma renin activity; the plasma reni... | 230,917 | [
-0.06613327,
0.04347999,
-0.7966965,
0.01935758,
-0.160205,
-0.01859542,
-0.228823,
0.2393629,
0.1752452,
-0.05387391,
0.02860338,
0.5434598,
0.1735186,
-0.3716828,
-0.381368,
-0.3136303,
0.08591121,
0.1033736,
-0.08504139,
0.3783717,
-0.005149999,
0.1591056,
-0.1806738,
... |
[Coprologic diagnosis of amebiasis : the rectocolitis cell trap and the value of cultures]. | The authors give the differential characters of dysenteric amoebae and cells observed in the feaces of patients affected by recto-colitis. In this purpose, they recall the usefullness of cultures for both the presence and the possibility of determination of the Amoebae. In short, they deplore the misappreciation of the... | 230,914 | [
-0.06234444,
-0.2355611,
0.1046544,
0.008017852,
0.01751669,
-0.2205407,
-0.1338364,
0.1987182,
0.05718024,
-0.2018575,
-0.04048055,
-0.184768,
0.1635831,
0.2240737,
-0.6604061,
-0.1333003,
-0.5230395,
-0.09290382,
-0.08289898,
0.04465693,
0.1373617,
0.1156114,
-0.0083127... |
Collateral circulation and stealmechanisms in innominate and subclavian artery obstruction. | Various types of collateral circulation and of intra- and extracerebral stealmechanisms have been described during the past two decades. The object of this short report is to discuss the clinical-angiographic data of two patients with extracranial cerebro-vascular occlusion, also in relation with current literature. Tw... | 230,934 | [
-0.187577,
0.2257712,
0.1112253,
-0.2133093,
0.09043662,
-0.1793086,
-0.4707875,
-0.2373902,
-0.07443488,
0.3377882,
-0.1693333,
0.1465858,
-0.2794402,
-0.3139052,
0.07029622,
0.02439252,
-0.02401275,
0.0895294,
0.03630561,
-0.2399006,
0.1583835,
0.1700229,
0.2759262,
0... |
Assessing the need for follow-up: the relationship of prognosis to posthospitalization adjustment. | Parents of children (N-64) hospitalized at a psychiatric hospital between the years 1971 and 1976 rated their child's adjustment in a number of behavioral areas. Problems in school, making friends, acting age-appropriately, and handling aggression were reported to be the major sources of difficulty for 40% of the forme... | 230,944 | [
-0.1070432,
0.3680795,
-0.3195053,
-0.2983095,
0.1620988,
-0.3530732,
-0.201313,
0.1506122,
-0.1833145,
-0.03768583,
0.1778974,
-0.0002235077,
-0.1346664,
-0.1487973,
-0.2527314,
0.1017834,
0.2266092,
0.3393072,
0.05829607,
0.2439778,
0.09802885,
-0.09219306,
-0.2595418,
... |
Cyclic nucleotides and ethanol tolerance and dependence. | Acute ethanol administration decreases cyclic AMP levels in brains of some animal strains. The ethanol-induced decrease of cyclic GMP levels cannot be blocked by intraventricular infusion of calcium but it can be prevented by pretreatment with pyrazole. Although cyclic AMP levels in the cerebral cortex change reciproca... | 230,949 | [
-0.1971695,
-0.240839,
-0.3644689,
-0.2710956,
0.2578005,
-0.2865791,
-0.08837977,
-0.2425752,
0.17678,
0.1289617,
0.03900447,
0.00372408,
-0.1932738,
0.1021608,
-0.1891629,
-0.1234299,
-0.4564083,
-0.05608617,
-0.3122385,
0.2044699,
0.2911803,
-0.01720503,
0.1486598,
0... |
Purification and properties of a phosphorylase (phosphoprotein) phosphatase associated with an alkaline phosphatase of Mr 35000 from bovine adrenal cortex. | A metal-ion-independent, nonspecific phosphoprotein phosphatase (Mr = 35000) which represents the major phosphorylase phosphatase activity in bovine adrenal cortex has been purified to apparent homogeneity. An alkaline phosphatase activity (p-nitrophenyl phosphate as a substrate) of the same molecular weight, which req... | 230,963 | [
-0.110056,
0.007858663,
0.02814734,
-0.1165177,
-0.3606574,
-0.1330115,
-0.2124549,
0.1804751,
0.09335722,
0.06054338,
0.06435083,
-0.1320168,
-0.02155241,
-0.2681212,
-0.7471392,
0.2194271,
-0.2735763,
0.06186706,
0.1724543,
0.3137194,
0.2039265,
-0.2406684,
-0.1757716,
... |
Polygraphic study during whole night sleep in infantile spasms. | The whole night EEG were polygraphically recorded and analyzed in 9 patients with infantile spasms prior to ACTH therapy. The subjects were divided into two groups, favorable and unfavorable, depending upon the response to the ACTH therapy. (1) Among the unfavorable group, the deep sleep stage was not observed; while t... | 230,967 | [
0.1917254,
0.0112711,
-0.1523142,
-0.3682707,
0.1247581,
-0.2034209,
0.003096803,
-0.2303019,
-0.1493294,
0.09099149,
-0.03228662,
-0.08368006,
-0.08188369,
0.2623049,
-0.2812168,
0.1145546,
-0.3228306,
0.2480508,
0.374104,
-0.3270637,
0.5301589,
0.08420768,
-0.06192994,
... |
Computerized automated syndromic and topographical neurologic diagnosis of lesions of the cranial nerves. | A system is described which, by means of a digital computer, computes from a previously automatically recorded objective neurologic finding a syndromic and topographical conclusion. For the present the system is designed and checked for lesions of the cranial nerves, but its principle is appropriate for the whole syndr... | 230,968 | [
-0.05801403,
0.01773579,
0.0277903,
-0.3382626,
0.02045429,
-0.3118539,
-0.3968158,
-0.1887096,
0.1630405,
0.06498479,
0.1725868,
0.1164524,
0.1241174,
-0.08600128,
-0.4732358,
0.02994342,
-0.3878989,
0.09624952,
-0.0288071,
-0.1023518,
0.05251414,
0.07710662,
-0.1079278,... |
Structural investigation of the antibiotic ristomycin A. The amino acid constituents. | Hydrolysis of the O-methylated aglycone of ristomycin A by a mixture of KOH and NaBH4 yielded a mixture of aromatic amino acids which, after N-acetylation and O-methylation, were separated by chromatography on silica gel. Compounds III approximately VII were isolated and identified by pmr and mass spectroscopy. Compoun... | 231,028 | [
-0.1792957,
0.4895387,
0.3535371,
0.2129603,
0.06698306,
0.2222978,
-0.2359566,
0.297533,
0.2576661,
-0.0719226,
0.09582099,
0.01187818,
0.1338603,
0.0851412,
-0.05173523,
0.128694,
-0.6105375,
0.2473405,
0.2040033,
0.07786071,
0.5910237,
0.1148539,
-0.1278126,
-0.43760... |
High-performance liquid chromatographic assay for acid and alkaline phosphatase in serum. | High-performance liquid chromatography was used to assay serum acid and alkaline phosphatase. Samples were incubated with adenosine-5'-monophosphoric acid (AMP) in a buffer of required pH, 5'-nucleotidase was inhibited with Ni2+ ions, and the phosphatase activity was determined by measuring the concentration of the rea... | 231,044 | [
-0.03578693,
-0.1867491,
-0.3965832,
-0.1336725,
0.2328161,
-0.02816477,
-0.3876756,
0.2987973,
0.2145228,
-0.1069108,
0.1241002,
0.009118681,
0.001592237,
0.0670251,
-0.4036141,
0.08895411,
-0.251291,
0.2141533,
-0.1912602,
0.3596062,
0.6579888,
0.005613117,
-0.26862,
... |
Use of protein A-treated sera in unmasking herpes simplex virus type 1 (HSV-1) immunoglobulin A and identifying HSV-1 immunoglobulin G as the predominant neutralizing antibody. | Treatment of human sera with protein A reduced the amounts of immunoglobulin G (IgG), IgA, and IgM detected by radial immunodiffusion. This treatment also decreased the amount of herpes-specific IgG and IgM detected by radioimmunoassay, whereas it increased and even unmasked the amount of herpes-specific IgA detected. ... | 231,047 | [
-0.08520307,
-0.1369127,
-0.2775837,
-0.1671487,
0.2436485,
-0.06920194,
-0.2489115,
0.05634238,
0.1946677,
0.2198705,
0.3371071,
0.1122943,
0.1520671,
-0.1175456,
-0.1425008,
-0.07524159,
-0.05686165,
0.02708063,
-0.2172956,
0.09529877,
0.2358988,
-0.1432042,
-0.1258941,... |
The packeted release of transmitter from the sympathetic nerves of the guinea-pig vas deferens: an electrophysiological study. | 1. Excitatory junction potentials (e.j.p.s) were recorded intracellularly in the guinea-pig vas deferens following stimulation of the hypogastric nerve. Differentiation of the rising phase of the e.j.p. showed them to be made up of transient peaks in the rate of depolarisation, the 'discrete events'. 2. In any one cell... | 231,103 | [
-0.05142946,
-0.1192984,
-0.3178317,
-0.2606223,
0.3243521,
-0.6311803,
-0.07599434,
0.0559631,
0.007278026,
-0.1204747,
0.2309296,
-0.02095724,
0.1207832,
-0.1342179,
-0.6720541,
-0.4390827,
-0.654068,
0.1127689,
0.4103462,
0.1022049,
0.2361746,
0.03714985,
0.08921923,
... |
[Phosphohydrolase activity of Pseudomonas maltophilia]. | The activity of phosphohydrolase (acid, alkaline, pyrophosphatase) was studied in two strains of Pseudomonas maltophilia: VCM-B-591 and SSE-B-715. The activity of these enzyme systems in these strains was found to be much higher than in other Pseudomonas species, viz. Ps. aeruginosa VCM-B-889, Ps. fluorescens VCM-B-553... | 231,188 | [
-0.216801,
-0.3816686,
-0.2250789,
-0.09582105,
-0.4433099,
0.01394584,
-0.208363,
0.2397137,
-0.2603926,
-0.05854338,
0.06173359,
0.1420833,
-0.4593474,
-0.1448543,
-0.3691114,
0.2157882,
-0.3863128,
0.07126115,
0.4162388,
0.3282212,
0.7531734,
0.5465234,
-0.2767465,
0... |
High-affinity binding of [3H]muscimol to subcellular particles of a neurone-enriched culture of embryonic rat brain. | High-affinity, Na+-independent binding of [3H]muscimol (KB approximately equal to 1.6 x 10(-8) M; Bmax approximately equal to 0.14 nmol/g pellet) occurred to a frozen-thawed particulate fraction of 74-h-old neurone-enriched cultures prepared from the cerebra of 12-13-day-old rat embryos. This finding provides evidence ... | 231,232 | [
-0.05874965,
-0.2658486,
-0.1617903,
-0.1635121,
0.1183068,
-0.06992512,
-0.4385253,
-0.01597244,
0.04471883,
0.1262531,
0.1782139,
0.2684156,
0.2554198,
0.14151,
-0.4016567,
-0.004046671,
-0.6017925,
-0.008517161,
0.2152305,
0.344483,
0.6646456,
0.1518255,
-0.008924783,
... |
Morphine presynaptically inhibits a ganglionic cholinergic synapse. | The effects of morphine on synaptic transmission through the inferior mesenteric ganglion (IMG) were studied using intracellular recording techniques. Morphine produced a reversible, dose-dependent reduction in the quantal content of the synaptic potentials with little or no effect on quantal size or the properties of ... | 231,236 | [
0.06625139,
0.04863464,
-0.3805534,
-0.3416188,
-0.09819758,
-0.2525216,
0.0005419104,
-0.364372,
0.1488712,
-0.3976212,
0.08731691,
-0.1861594,
0.004578673,
0.04553917,
-0.5347542,
0.128949,
-0.7681887,
0.06043509,
0.5392264,
0.09982786,
0.0478231,
-0.03729243,
0.4671431... |
Diurnal changes in melatonin binding sites of hamster and rat brains. Correlations with neuroendocrine responsiveness to melatonin. | A diurnal variation in neuroendocrine sensitivity to melatonin is known to occur in hamsters and rats. The present experiments were carried out to examine the possibility that affinity and/or number of melatonin binding sites in brain could change accordingly at the two times when exogenous melatonin is known to be ine... | 231,243 | [
-0.02170959,
-0.1100856,
-0.2712372,
-0.2360007,
0.1893991,
-0.1760648,
-0.3856116,
-0.02080111,
0.1047271,
-0.1447688,
0.2614474,
0.1522573,
0.2716278,
-0.5072044,
-0.511946,
-0.1363795,
-0.4822935,
0.1392859,
0.13242,
0.04928526,
0.09004701,
0.0516524,
0.01227515,
-0.... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.