title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Effect of selection for high egg production in chickens on shedding of lymphoid leukosis virus and gs antigen into eggs. | Lymphoid leukosis virus (LLV) and group specific (gs) viral antigen were detected less frequently in albumen of eggs from two strains of Single Comb White Leghorns that had been selected for high egg production than in corresponding random-bred control strains, which represented the original base population. In a third... | 231,257 | [
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The relationship between Ca2+-mediated polyphosphoinositide phosphodiesterase activity, 1, 2-diacylglycerol accumulation, and microvesiculation in erythrocytes. | A variety of morphologic and metabolic changes occur in erythrocytes in which the intracellular level of Ca2+ is increased. These include echinocytosis followed by microvesiculation, K+ efflux, ATP degradation, and activation of polyphosphoinositide phosphodiesterase with the formation of 1,2-diacylglycerol and phospha... | 231,260 | [
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[Peripheral thrombophlebitis. "Paratuberculous syndrome" (author's transl)]. | The authors relate the case of a young North-African man who presented during one month several peripheral thrombophlebitis before a ganglionary tuberculosis of the mediastinum appear. With specific antibiotherapy, the cutaneous lesions disappear and can be so considered as a paratuberculous syndroma. | 231,317 | [
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[A further case of IgD myeloma (author's transl)]. | A 76-year-old woman was hospitalized for stabilization of her diabetic condition. The results of radiological, hematological, and biochemical investigations suggested the diagnosis of an IgD myeloma. A specific immune-serum was used to demonstrate the presence of monoclonal protein of the IgD lambda type. The course of... | 231,320 | [
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[Post-partum galactorrhea with hyperprolactinaemia persistent during a clonidine treatment (author's transl)]. | Persistence of a post-partum galactorrhea with an hyper-prolactinaemia leads to charge clonidin, an hypotensive-drug. When clonidine is stopped, galactorrhea and hyper-prolactinaemia case. Explanation of the role of the drug is uneasy. | 231,318 | [
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High pressure neurological syndrome: antagonistic effects of helium pressure and inhalation anesthetics on the dopamine-sensitive cyclic AMP response. | The antagonistic effects of helium pressure and certain inhalation anesthetics on the dopamine-sensitive cAMP response in the caudate nucleus of rat brain were examined. Helium pressure suppressed basal, dopamine-stimulated, and anesthetic-stimulated cAMP levels. These data indicate that by reversing the effects of pre... | 231,338 | [
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Needle cytology of the breast. A quantitative and qualitative study of the cells of benign and malignant ductal neoplasia. | Twenty-seven ductal breast lesions, including cases of intraductal hyperplasia, intraductal carcinoma and infiltrating carcinoma, were studied cytologically by means of the Nordenstrom screw technique. Qualitative and quantitative cellular features were evaluated and correlated with histologic findings in sections take... | 231,367 | [
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Malignant mixed müllerian tumors of the uterus. A clinicopathologic assessment of 34 cases. | We have analyzed clinical and pathologic features of a series of 34 patients with malignant mixed müllerian tumors of the uterus. This study includes 17 homologous and 17 heterologous lesions. The most significant prognostic indicator in our patients was tumor extent (stage) at diagnosis. Of lesser importance were the ... | 231,382 | [
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Bronchiolo-alveolar carcinoma with nodal metastases. An ultrastructural study. | A case of bronchiolo-alveolar carcinoma of the lung was studied by light and electron microscopy. Type II granular pneumocytes were seen in the lymph node metastases of the tumor, a finding not reported previously. We feel that the presence of these cells in metastatic foci indicates their neoplastic nature, and provid... | 231,385 | [
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[Structure of calf rotavirus. 1. Hydrodynamic and electron microscopic parameters of the virus]. | Rotavirus was isolated from the faeces of calves afflicted with diarrhoea and purified. Isolation was preceded by chloroform treatment, oxide wax A-precipitation, as well as differential and density gradient centrifugation. Virus density in CsCl solution was 1.38 +/- 0.01 g/ml. Cell culture virus prepared without chlor... | 231,417 | [
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Spinal canal stenosis in adult with hypophosphataemic vitamin D-resistant rickets. | A case is described of a 55-year-old male with hypophosphataemic vitamin D-resistant rickets, who presented with long-standing back pain and paraesthesiae in both legs considered to be due to osteoid encroachment on an already narrow spinal canal. Marked symptomatic improvement has followed extensive lumbar laminectomy... | 231,427 | [
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An immunofluorescence diagnostic test for avian infectious laryngotracheitis. | An antiserum to a recent field isolate of infectious laryngotracheitis virus was conjugated with fluorescein isothiocyanate and used to detect viral antigen to infected chorioallantoic membranes and trachael epithelium by the direct fluorescent antibody technique. In experimentally infected birds, viral antigen was det... | 231,428 | [
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Kinetics of 5--nucleotidase in sera of liver cirrhotic and normal Iraqi individuals. | 5'-Nucleotidase activity was elevated in patients with liver cirrhosis; greater values of 5'-Nucleotidase activity were found in biliary cirrhosis, 5'-Nucleotidase from liver cirrhotic sera was less stable than from normal sera. The velocity of 5'Nucleotidase from liver cirrhotic sera per minute, at t = 10, was greater... | 231,454 | [
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Polioviruses as indicator of virological quality of water. | Viruses were found in 47 out of 53 samples of raw domestic sewage collected over a 13-month period from a high socioeconomic level community. At least 39 out of these 47 samples contained polioviruses as was expected in a population where children were receiving Sabin live-attenuated vaccine. Polioviruses could then be... | 231,478 | [
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Lipid accumulation in the rat liver: a histological and biochemical study. | The sequential pattern of lipid accumulation and associated biochemical changes were studied in two commonly used experimental models of nutritional fatty liver in rats. Female rats were maintained for 8 weeks on high fat, low protein diets containing adequate methionine and choline, and drinking water ad libitum (Diet... | 231,500 | [
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Effects of interstimulus interval on latency of the brainstem auditory evoked potential. | Peak latency of the inferior collicular response (wave V) of the brainstem auditory evoked potential (BAEP) increases with decreasing interstimulus interval (ISI). The present research investigated relative peak shifts of major components of the BAEP in an attempt to identify the source of the observed shift in wave V.... | 231,579 | [
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The effects of EGTA and trypsin on the serum requirements for cell attachment to collagens. | Cells growing on plastic or glass surfaces in vitro may be brought into suspension by proteases (e.g. trypsin) or chelating agents (e.g. EGTA). Trypsin and EGTA remove different quantities and types of molecules from cell surfaces. Previous studies have revealed that when confluent cultures of either BHK or PyBHK cells... | 231,608 | [
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Properties of rat adrenal zona reticularis cells: production and stimulation of certain steroids. | The outputs of corticosterone, deoxycorticosterone and androstenedione from dispersed, purified rat adrenal zona reticularis and zona fasciculata cells have been measured by radioimmunoassay. Preferential production of deoxycorticosterone by zona reticularis cells was demonstrated by their higher basal deoxycorticoster... | 231,628 | [
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An improved method for estimating sequence divergence between related DNAs from changes in restriction endonuclease cleavage sites. | We have developed a theory to estimate the degree of sequence divergence between related DNAs from the comparison of restriction endonuclease recognition sites. Two major improvements have been made upon a similar method reported by Upholt (1977). First, the most probable value is calculated by the collective use of al... | 231,686 | [
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Radioimmunoassay of methionine enkephalin and interference by brain factor of immunoreactivity and opiate receptor binding activity. | We developed a radioimmunoassay of methionine-enkephalin (met-enk) which was found to be highly specific to the peptide and 1 pmol was the detection limit. Interference by the following peptides was practically negligible; leucine-enkephalin, LAP- or CNBr-treated met-end, alpha- and beta-endorphins. Morphine and its co... | 231,699 | [
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A restriction enzyme cleavage map of Tn5 and location of a region encoding neomycin resistance. | This paper reports a cleavage site map of Tn5 for restriction enzymes BamHI, Bg/I, Bg/II, Hind II, HindIII, HpaI, Sa/I, Aval, SmaI, XhoI, PstI, PvuII, HaeII and HaeIII that was determined by the analysis of restriction enzyme cleavage patterns of ColEl, two independent ColEl::Tn5 plasmids, and a ColEl::Tn5 deletion der... | 231,729 | [
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Chronological study of ultrastructural changes in the peripheral nerves in Marek's disease. | A chronological study was made of the ultrastructural changes in peripheral nerves following inoculation of 1-day-old chicks with a neurogenic strain of Marek Disease virus. No virus particles were found in nerves. Cellular infiltration of nerves was detected as early as 5 days after inoculation and by 3 weeks some ner... | 231,745 | [
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Self-administration of delta 9-tetrahydrocannabinol by rats. | The present study examines the dose-response pattern of delta 9-tetrahydrocannabinol self-injection in naive rats at 80% reduced body weight and 100% body weight, both conditions with a fixed-time 1 min (FT-1) food delivery schedule. The results indicated that food deprived animals tested on a FT-1 min schedule self-in... | 231,789 | [
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Hodgkin's disease and infectious mononucleosis. | Sequential sero-positive infectious mononucleosis is described in 3 sibs, 2 of whom subsequently developed Hodgkin's disease. EB virus antibodies were present in the serum of both cases. | 231,818 | [
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[Histological study of the bone marrow in 96 cases of Waldenstrom's macroglobulinemia. An evaluation with clinical, haematological and biological data (author's transl)]. | Bone marrow biopsy in Waldenstrom's macroglobulinemia shows three types of lesions: lympho-plasmocytic and reticular infiltration, which is the most common, reticular infiltration, and aplastic marrow, more seldom. In all cases the reticulinic network is increased and thickened. These lesions are diffuse or nodular. Di... | 231,825 | [
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[Sideroblastic anemia in a multiple myeloma treated by melphalan (author's transl)]. | A case of sideroblastic anemia arised in multiple myeloma is related. Eighteen cases of literature are studied. This evolution usually appears in old and remitted myeloma. The pathogeny of the sideroblastic anemia is unknown, and possibly related to leukemia complicating multiple myeloma. | 231,836 | [
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Silica and silicates in femoral lymph nodes of barefooted people in Ethiopia with special reference to elephantiasis of the lower legs. | Electron microscopy of femoral lymph nodes of barefooted Ethiopians show the presence of numerous particles of colloid-size and electron-density in the lysosomes of the macrophages in the gland. On diffraction analysis, the particles are found to be amorphous. Elemental microanalysis of the X-ray spectrum indicate the ... | 231,857 | [
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Endobronchial granular cell tumor. Cytology of a new case and review of the literature. | We report the 45th case of endobronchial granular cell tumor in the literature and describe in detail the cytologic findings in bronchial brushings and post-brush washings. Our findings differ from those of the only other cytologic report of such a lesion. We review the literature and summarize the clinical and patholo... | 231,879 | [
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Partial trisomy 20 confirmed by gene dosage studies. | We describe a female infant with multiple congenital anomalies and mental retardation, pre- and postnatal growth failure, microcephaly, unusual facial appearance, and minor skeletal anomalies, all very suggestive of the partial trisomy 20(p) syndrome. Although she was born to karyotypically normal parents, she had an e... | 231,907 | [
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Hormone producing pancreatic islet cell carcinoma: changing clinical presentation. | A patient with pancreatic islet cell carcinoma demonstrated spontaneous remission and recurrence of hyperinsulinism and disappearance of elevated plasma motilin levels. Despite evidence for gastrin production by the tumor initially, the Zollinger-Ellison syndrome was not diagnosed until three years after initial presen... | 231,906 | [
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Prostaglandin mediated inflammatory changes induced by alpha-adrenoceptor stimulation in the sympathectomised rabbit eye. | Topical application of 50 microliter of 0.1% noradrenaline or 10% phenylepherine to either a surgically sympathectomised or a guanethidine treated rabbit eye induced a transient increase in intraocular pressure (IOP), between 90 and 150 min, followed by a fall to hypotensive levels. These changes were accompanied by th... | 231,913 | [
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Locally recurrent carcinoma after breast reconstruction. | The incidence of locally recurrent carcinoma after mastectomy is low--between 6 and 20%. Recent case histories of 4 patients who were clinically free of breast carcinoma and who developed local recurrence after reconstruction are reviewed. Possible relationships of breast reconstruction to local recurrence are discusse... | 231,919 | [
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Serum lipoprotein lipids after gemfibrozil treatment. | The changes of serum lipoprotein lipids including the phospholipids of twelve hyperlipoproteinemic patients were studied after a four weeks treatment with 1200 mg/day gemfibrozil. There was a decrease of all VLDL lipids as well as of LDL and HDL triglycerides and an increase of HDL cholesterol. The phospholipids were i... | 231,950 | [
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Purification of pig synovial collagenase to high specific activity. | 1. Pig synovium in tissue culture secretes a specific collagenase in a latent form. 2. The latent enzyme was concentrated by (NH4)2SO4 precipitation and activated with 4-aminophenylmercuric acetate, and the active enzyme was purified by chromatography on Ultrogel AcA44, DEAE-cellulose, heparin-Sepharose and a zinc-chel... | 231,970 | [
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Effects of an angiotensin converting enzyme inhibitor on psychosocial hypertension in mice. | 1. Renin-associated, chronic psychosocial hypertension of 150-160 mmHg develops in groups of mice interacting socially in complex population cages. 2. The blood pressures of 16 males in a cage were measured and an intraperitoneal injection of the angiotensin coverting enzyme inhibitor captopril (SQ 14,225) was given. T... | 232,019 | [
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Comparative beta-adrenoreceptor-blocking effects and pharmacokinetics or propranolol and pindolol in hypertensive Africans. | 1. The beta-adrenoreceptor-blocking effects of pindolol were compared with those of propranolol and a placebo in a double-blind cross-over trial involving nine hypertensive African patients. 2. Heart rate, systolic blood pressure and diastolic blood pressure were measured at rest and immediately after exercise before a... | 232,026 | [
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The ultrastructure of renomedullary interstitial cells in short duration hypercalcemia induced by vitamin D3. | Under short duration hypercalcemia induced by pharmacological doses of vitamin D3 significant ultrastructural changes were observed in the renomedullary interstitial cells of rats. The most striking alteration was the degranulation of these cells accompanied with the increase in volume of the rough and smooth-surfaced ... | 232,048 | [
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Induction of alkaline phosphatase activity in HeLa cells by sodium butyrate. | The induction of HeLa cell alkaline phosphatase activity by sodium butyrate could be inhibited by the coadministration of caffeine or theophylline. The inhibitions were dose dependent, and at any given concentration the potency was theophylline greater than caffeine. Although the induction by sodium butyrate was more s... | 232,057 | [
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A serological survey of St Lucia. | A serological survey of a random sample of 541 of the population of St Lucia was undertaken. The prevalence of antibodies to dengue, herpes virus, VZ, rotavirus, rubella and syphilis is described and compared with other communities. | 232,090 | [
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Molecular relationship of the DNA and RNA of intracytoplasmic A particles to mouse and mammary tumour virus genomes. | We have directly tested the hypothesis that single-stranded cytoplasmic A particle-associated DNA (ss CAP DNA) is a murine mammary tumour virus (MMTV) proviral intermediate by hybridizing 125I-labelled ss CAP DNA to MMTV RNA or to MMTV complementary DNA (cDNA). 125I-labelled CAP DNA did not form duplexes with either MM... | 232,129 | [
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Biodistribution and pharmacokinetics of S-35-labeled 5-thio-D-glucose in hamsters bearing pancreatic tumors. | 5-thio-D-glucose (5-TDG) exerts profound effects on rapidly metabolizing tissues. We have used liquid scintillation counting to study the tissue distribution and pharmacokinetics of S-35-labeled 5-TDG in hamster models of pancreatic tumors. In the normal hamster, initial uptake of S-35 activity into kidney, liver, and ... | 232,149 | [
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Dystrophic calcification in calcifying epithelial odontogenic tumor: an X-ray diffraction and electron spin resonance study. | X-ray diffraction and electron spin resonance (ESR) analyses were conducted on calcifying epithelial odontogenic tumor (CEOT) associated with abundant calcification in order to compare its mineral structure with that of surrounding cortical bone. The material under investigation was removed from the canine-premolar reg... | 232,157 | [
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Characterization of infectious oncornaviruses from MOPC-460 plasmacytomas: their relation to A-type particles. | MOPC-460 mouse plasmacytoma cells produce intracellular A-type particles and extracellular oncornavirus-like particles ("myeloma-associated virus," abbreviated MAV). The genomes of these two particles are closely related. During attempts to establish infections with MOPC-460 extracellular particles, we isolated ecotrop... | 232,165 | [
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Effects of phenylephrine and isoproterenol on the activity of cyclic AMP-dependent protein kinase of hypothyroid rat tissues. | The present study was designed to examine the properties of cyclic AMP-dependent protein kinase from normal and hypothyroid rat tissues. The activity of the liver enzyme decreased in hypothyroid rats and this reduced activity may be due to the decrease in synthesis of enzyme protein. The enzyme activity from the kidney... | 232,200 | [
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Sensitivity of chemically treated spores of Clostridium perfringens type A to an initiation protein. | Extraction of Clostridium perfringens type A spores with dithiothreitol (DTT), DTT plus sodium dodecyl sulphate (DTT-SDS), urea-mercaptoethanol (UME), or alkali, solubilized from 18.6 to 46.5 of the total dry weight of spores. The initiation of germination and lysis of such treated spores with lysozyme and an initiatio... | 232,233 | [
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0.175... |
[Worldwide eradication of smallpox or from Sarah Nelmes to Ali Maow Maalin]. | It cannot be disputed that the WHO plan for the eradication of smallpox has had considerable success. There is no endemic smallpox any longer in the world. Nevertheless caution is advised and continued supervision must not be neglected. There are still countries where supervision is not satisfactory, there is uncertain... | 232,247 | [
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Effect of serum and blood on Enterobacteriaceae grown in the presence of subminimal inhibitory concentrations of ampicillin and mecillinam. | Bacteria from the strains of five species of Enterobacteriaceae grown in the presence of subminimal inhibitory concentrations of ampicillin or mecillinam formed into filamentous or round cells. These filamentous and round cells as well as normal control bacteria were incubated with either fresh human serum or blood, th... | 232,297 | [
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The effect of sympathicomimetic agents on carbohydrate metabolism of planaria. | Epinephrine, ephedrine, dopamine and isoproterenol considerably influence carbohydrate utilization in planaria. Dopamine alone and in combination is the most potent, while ephedrine the least effective in this respect. The finding of increased responses to combined treatment supports the view of the existence of differ... | 232,357 | [
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Effect of acupuncture on adrenocortical hormone production: I. Variation in the ability for adrenocortical hormone production in relation to the duration of acupuncture stimulation. | The effect of acupuncture on adrenocortical hormone production in adult female albino rabbits of New Zealand strain was investigated. There was significant increase compared to the control cortisol and corticosterone following application of acupuncture at the locus Tsu-San-Li. In the non-locus group, such treatment re... | 232,372 | [
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Neurogenic tumors of the head and neck in children. | A retrospective analysis of deep-seated neurogenic tumors of the head and neck in children seen at the University of Michigan Medical Center was done. There were 22 patients--10 with plexiform neurofibromas, 3 with neurofibromas, 2 with esthesioneuroblastomas, 2 with neurilemmomas, 1 with neurogenous sarcoma, and 4 wi... | 232,389 | [
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... |
Preoperative estimation of operative risk in liver surgery, with special reference to functional reserve of the remnant liver following major hepatic resection. | Hepatic functional reserve was evaluated in 76 patients with known liver, biliary tract or pancreas diseases using kinetic analysis of removal of indocyanine green (ICG) with special reference to maximal removal rate (Rmax). In surgery other than hepatectomy, if ICG Rmax is below 0.4 mg/kg/min the operative risk should... | 232,519 | [
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Tumorigenicity of revertant from an SV40-transformed line. | A syndrome of in vitro properties correlates with the tumorigenicity of SV40-transformed rodent cells. These properties are: plasminogen activator production, loss of large actin cables, and anchorage-independent growth. An established rat fibroblast line, its SV40 transformant, several T-antigen negative revertants, a... | 232,523 | [
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Regulation of dome formation in differentiated epithelial cell cultures. | Rat mammary (Rama 25) and dog kidney (MDCK) epithelial cell cultures formed 'domes' of cells due to fluid accumulation in focal regions between the culture dish and the cell monolayer. Addition of ouabain caused collapse of domes, suggesting that transport functions were required for maintenance of domes. Dome formatio... | 232,529 | [
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[Angioimmunoblastic lymphadenopathy: ultrastructural study of lymph nodes. Possible relationship with Epstein-Barr Virus (EBV) (author's transl)]. | Angioimmunoblastic lymphadenopathy (AIL) has been clinically and histopathologically described by several authors since 1972, but only a few papers have analyzed the morphological aspects of the lymph nodes as observed by using electron microscopy. In the past three years, we happened to see in the Curie Institute two ... | 232,552 | [
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... |
Psychologic correlates of serum indicators of stress in man: a longitudinal study. | Correlations between serum uric acid, cortisol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol and psychometric indices of stress--namely, anxiety, hostility, and depression--were investigated in 20 students over a 2 1/2 month academic quarter. There were three peak periods of str... | 232,553 | [
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0.2395736,
0.06055168,
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0.1065803,
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0.169046,
0.1883149,
0.02604762,
0.146761,
-0.08858387,
... |
Sentence memory and sleep: a pilot study. | In four consecutive weekly sessions 12 subjects, aged 20--25 years, listened to a sentence stimulus before the onset of sleep and were asked to reproduce it after an awakening provoked during stage 2 or REM sleep of the first cycle. Recall of the sentence stimuli heard before sleep was affected by their semantic accept... | 232,564 | [
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0.08538083,
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0.2881669,
0.1238979,
0.090767... |
The preservation of medically important fungi. | Details are given of a method, first described in 1962, for preservation of fungi in anhydrous silica gel. It is shown that the procedure is suitable for use with dermatophytes, yeasts and other fungi of medical importance and that they may be preserved for periods of 5 years or more. | 232,575 | [
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0.1169215,
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0.2093832,
0.0981129,
0.3161403,
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Increased mutation rates in doubly viral transformed Chinese hamster cells. | An untransformed parental Chinese hamster cell line, one polyoma transformed clone, and two clones containing both SV40 and polyoma DNA were tested for the appearance of variants resistant to 6-thioguanine or oubain. The frequency of such variants was found to be highest in doubly transformed cells. The mutation rate a... | 232,576 | [
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0.3250545,
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... |
Studies on the substrate specificity of the DNA methylase activity from Escherichia coli K-12. | A partially purified extract of DNA methylases from E. coli K-12 containing DNA-adenine as well as DNA-cytosine methylase activities has been examined with respect to different DNA species as substrates. The results show that the natural content of 6-MAP) in the applied DNA represses the DNA-adenine methylase activity.... | 232,591 | [
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Expression of aspartokinase, dihydrodipicolinic acid synthase and homoserine dehydrogenase during growth of carrot cell suspension cultures on lysine- and threonine-supplemented media. | Reduction in the amounts of activity of the first enzyme, aspartokinase (EC 2.7.2.4) and two branch-point enzymes, dihydrodipicolinic acid synthase (EC 4.2.1.52) and homoserine dehydrogenase (EC 1.1.1.3), located in the pathway for the synthesis of aspartate-family amino acids, occurred when cell suspension cultures of... | 232,596 | [
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0.1398754,
0.1031775,
0.2682495,
0.2683551,
0.3121973,
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0.06313... |
On the action of diethyldithiocarbamate as inhibitor of copper-zinc superoxide dismutase. | The rate constants of the reactions between pulse radiolytically produced superoxide radicals and the Cu(II) chelate of diethyldithiocarbamate were determined at pH 7.0. It was found that diethyldithiocarbamate forms a copper complex, which as no dismutating activity. The removal of the protein bound copper in superoxi... | 232,599 | [
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0.2186368,
0.2782018,
0.150743,
0.03884776,
... |
Effect on renal function and renin secretion of noradrenaline infused into the renal artery. | Effect of noradrenaline on renal function and renin secretion was studied during infusion into the renal artery of anaesthetized dogs. Experiments were performed with or without alpha or beta receptor blockade. Noradrenaline infusion resulted in a significant elevation of renin secretion associated with marked vasocons... | 232,613 | [
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0.0771146,
0.1426241,
0.0403088,
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Thiourea derivatives as specific inhibitors of picorna viruses. | 30 compounds with antipicorna virus activity were selected from 173 N,N'-disubstituted thiourea derivatives. The spectrum of antiviral activity was determined in vitro using entero, FMD, rhino and EMC viruses. Structure-activity relationships were studied. Several compounds produced marked activity against coxsackie vi... | 232,663 | [
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Characterization of Immunosuppression in chickens by infectious bursal disease virus. | Chickens were infected with infectious bursal disease (IBD) virus in ovo or at different times posthatching to 6 weeks of age. The B- and T-cell responses in the lymphoid tissues and blood were examined sequentially to 8 weeks of age by using indirect immunofluorescence. The proportion of B-cells was consistently lower... | 232,660 | [
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0.0... |
1H NMR study on the interaction of cupric ion with ribonuclease A. | The reassignment of the 1H NMR C-2 histidine signals of the bovine pancreatic ribonuclease A has required a revision of the 1H NMR data on the role of the different histidines in their interaction with the Cu2+. The results of our measurements carried out at p2H 5.5 and 7.0 reduce the importance of His-12 as main site ... | 232,664 | [
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0.1855323,
0.2289458,
-0.07515... |
Interaction of infectious bursal disease and coccidiosis in layer replacement chickens. | During a floor-pen study on anticoccidial programs for layer-replacement pullets, there was a natural outbreak of infectious bursal disease (IBD). The interaction of coccidiosis and IBD was characterized by: excessive deaths from coccidiosis; and apparent failure of some anticoccidial drug treatments. Immunity to cocci... | 232,661 | [
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0.1660832,
0.303288,
0.006491859,
0.04381063... |
Purification of soluble hepatocellular carcinoma extracts. | When soluble hepatocellular carcinoma (HCC) extract prepared by 3 M KCl solution was passed through a column of Sephadex G-200, four fractions (designated as I, II, III, IV) could be obtained from the elution profile. By leukocyte migration inhibition assay, the active component of soluble HCC extract which represented... | 232,674 | [
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... |
[Diabetic polyneuropathy. 4. Synopsis of electroneurographic findings in diabetics]. | Sensory conduction velocity of the median nerve, motor conduction velocity of both median and tibial nerves, and corresponding distal laterncies are sufficient parameters to establish the diagnosis of polyneuropathy almost with certainty. Considering these six parameters yielded in detection of peripheral nerve dysfunc... | 232,678 | [
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0.3014722,
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0.1699764,
... |
Resistance of C58 mice to primary systemic herpes simplex virus infection: macrophage dependence and T-cell independence. | The relative contribution of thymus-derived lymphocytes (T-cells) and of macrophages to resistance to primary infection with herpes simplex virus type 1 (HSV-1) was studied in C58 mice. Resistance was dependent on macrophage competence, but was relatively independent of T-lymphocyte competence. Although aging mice beca... | 232,692 | [
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0.2505322,
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Urine analysis of platinum species derived from cis-dichlorodiammineplatinum(II) by high-performance liquid chromatography following derivatization with sodium diethyldithiocarbamate. | A clinically useful method is described for the quantitative analysis of platinum species derived from cis-dichlorodiammineplatinum(II) in urine. The drug and its biodegradation products are derivatized directly in urine by reaction with sodium diethyldithiocarbamate (DDTC) to form a common product, a 2:1 DDTC-platinum... | 232,706 | [
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... |
Clinical aspects of gut enzymology. | Enzymological alterations in functional disturbances and in diseases of the intestine are reviewed. Examples are given for diagnostic significance (e.g. in Hirschsprung's and Crohn's diseases), for pathogenetic considerations (e.g. in hypolactasia and in celiac disease), and for secondary involvement of the liver (e.g.... | 232,715 | [
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0.3117656,
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0... |
[Comparison of the effects of analgesia-producing peripheral and central stimulations in cats. Effect of nalorphine (author's transl)]. | The effects of weak intensity percutaneous peripheral stimulations (SPPc) on the transmission of nociceptive messages induced by stimulation of the dental pulp have been studied on anaesthetized cats. 1. The jaw opening reflex (ROG) and the evoked potentials in the thalamic center median (CM), by stimulation of the den... | 232,725 | [
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0.1066863,
... |
[Collagenase inhibition: an experiment in the treatment of scleromalacia perforans (author's transl)]. | Report on local application of Cystin eye drops in a case of scleromalacia perforans. This medication brought the necrotizing disease process to a standstill. There was even discrete neoformation of scleral tissue, which we attribute to the collagenase inhibiting action of this drug. | 232,732 | [
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0.... |
[Corneal deposits in children on dialysis and treatment with vitamin D3 and 1,25 DHCC (author's transl)]. | The corneas of 15 children on intermittent long-term dialysis for renal failure were studied, first during a period of treatment with high doses of vitamin D3 and subsequently during a study with the vitamin D metabolite 1,25 DHCC. Metastatic calcification of the limbus or increased limbic deposits only occurred during... | 232,733 | [
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0.4504442,
0.3894013,
0.2732561,
0.2033264,
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0.... |
DNA glycosylases of human lymphoblastoid cells. | Lymphoblastoid cell lines were established after transformation by Epstein-Barr virus of peripheral lymphocytes from xeroderma pigmentosum (XP) patients and normal donors. These lines expressed B-lymphocyte characteristics. Typical characteristics related to XP of these cell lines were not altered by transformation. Ex... | 232,757 | [
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0.4205955,
0.2112294,
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Photobinding of 8-methoxypsoralen and changes in nuclease digestability of replicating SV40 chromatin. | To analyze the structure of the replicating regions of simian virus 40 nucleoprotein complex (SV40 chromatin), photochemical binding of 8-methoxypsoralen (8-MOP) and changes in digestability with micrococcal nuclease were studied. 8-MOP bound preferentially to the linker DNA of nucleosomes and strongly inhibited nuclea... | 232,760 | [
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0.1765357,
0.3058015,
0.4644483,
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-0... |
Prostacyclin stimulation of dog arterial cyclic AMP levels. | Prostacyclin (PGI2) dose-dependently increases the adenosine 3',5'-cyclic monophosphate (cyclic AMP) levels in canine femoral, carotid, and canine and bovine coronary arteries. The prostacyclin-stimulation is enhanced by phosphodiesterase inhibitors, and is readily measurable after 60 sec incubation. The prostaglandin ... | 232,764 | [
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0.02108266,
... |
[Cancer of the alpha cells of the pancreas]. | Endocrine tumors of the pancreas are rare. One of them is the so called alpha cell carcinoma also called glucagonoma usually associated with diabetes and skin lesions somewhat typical. A case of a male patient fifty-three years of age with clinical diabetes mellitus and generalized dermatitis is presented. The pancreat... | 232,767 | [
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0.4011758,
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... |
[Acute thrombocytopenic purpura associated with fenoprofene (author's transl)]. | A 73-year-old woman, taking daily 3 to 4 tablets (900 to 1200 mg) of fenoprofene for 2 weeks, had a purpura related to an acute peripheric thrombocytopenia (platelet count of 24 000/mm3) with fast regression when we have stopped therapy. It is the second case of literature. This drug is also capable of causing acute ag... | 232,784 | [
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0.04885651,
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... |
Myofibrillar proteins, enzyme activity and fibre types in human skeletal muscle. | The myofibrillar proteins and relative LC-3 content of myofibrils prepared from five different, left and right muscles of the human forearm were studied by electrophoresis in 10% SDS-polyacrylamide gels followed by densitometry. The specific K-activated ATPase activity of the myofibrillar myosin of the myofibrils was d... | 232,809 | [
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0.06728626,
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0... |
[Adrenocortical function in hyperprolactinemia. The study of glucocorticoids, mineralocorticoids and androgens in chronic and acute hyperprolactinemias (author's transl)]. | Glucocorticoids, mineralocorticoids, and adrenal androgens were studied in 3 groups of patients: control subjects (group I), hyperprolactinemic subjects (group II) and miscellaneous patients including chromophobe adenomas and normalized hyperprolactinemic subjects treated with Bromocriptine (group III). All the patient... | 232,834 | [
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... |
[Studies of the regulation potential of glucose metabolism in the calf following infusion of fructose solution and using various hormones (ACTH, prednisolone, adrenaline and noradrenaline)]. | Infusion of fructose solution (25 g in 100 ml) in sugar rations of 0.5 g or 1.0 g per kilogram of body weight usually induced in calf temporary drop of glucose in the blood plasma. This was attributable to rise in insulin secretion and glucose conversion or insufficiently fast effectiveness of insulin antagonists (adre... | 232,842 | [
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0.03803756,
... |
Bovine fetal inoculations with calf rotavirus. | The serological and histopathological responses of bovine fetuses to in utero inoculation with virulent and attenuated strains of the calf rotavirus (reovirus-like agent of neonatal calf diarrhea) are described. Thirteen bovine fetuses, 63 to 190 days of gestation, were inoculated in utero with attenuated (three fetuse... | 232,853 | [
-0.2178369,
-0.2522252,
-0.00342048,
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0.04973187,
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0.04771823,
0.2637941,
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0.1124998,
0.3652161,
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0.1541777,
0.02299359,
-0.3905074,
0.47014,
0.0274628... |
[Cyto-immunochemical detection of gamma endorphin in swine adenohypophysis]. | An immunserum was prepared from gamma endorphin and its specifity was checked by the indirect method. It was tested on hypophysis which were taken from Pigs since birth till 3 months old. The anterior lobe as well as the intermediate lobe have reacted. The same cells were positive in the anterior lobe and recognized th... | 232,857 | [
-0.01885406,
-0.330574,
0.01374326,
0.3023078,
0.09578042,
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0.2148739,
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0.1181309,
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0.310855,
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0.1671074,
0.1691289,
0.4705762,
0.5802224,
0.1263815,
-0.1840636,
-0.3685... |
A family with massive acute vitamin D intoxication. | Acute massive vitamin D overdosage occurred in a family after eating food cooked in a nut oil containing 5 million units of vitamin D3/ml. The plasma vitamin D was 55 and 60 i.u./ml in the father and mother respectively, and 9.6 i.u./ml in their 11-month-old infant (normal range, 0--1.6 i.u/ml). All the family presente... | 232,912 | [
-0.3032796,
0.2897326,
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0.2988406,
0.602531,
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0.2482937,
0.1935859,
0.0402953,
0.3933927,
0.1685876,
-0.2020091,
... |
Renal osteopenia - an assessment of long-term therapy with vitamin D analogues. | Renal bone disease was assessed for an average of 5.5 years in 9 patients on maintenance haemodialysis. The investigative methods included serial biochemical estimations, radiographic skeletal surveys and quantitative bone histology. Repeated bone mineral analyses and neutron activation analyses of a hand were also per... | 232,916 | [
-0.1635601,
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0.04581439,
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0.03568102,
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0.1272051,
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0.2007166,
0.04743686,
0.1746794,
0.2077982,
0.4428204,
-0.340606,... |
A new function for ceruloplasmin as an acute-phase reactant in inflammation: a scavenger of superoxide anion radicals. | In summary, purified human ceruloplasmin inhibits several reactions mediated by superoxide anion in a fashion consistent with an ability to scavenge this free radical. It must be pointed out, however, that on a weight basis, the superoxide-scavenging activity of ceruloplasmin is substantially less than that of purified... | 232,945 | [
-0.2224371,
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0.02752341,
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0.2096301,
0.09312534,
0.1297583,
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0.07182847,
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... |
[Neurologic syndromes affecting the shoulder (author's transl)]. | A number of locally defined as well as generalised diseases of the peripheral nervous system is manifested in the shoulderarm region besides lesions of individual nerves through traumas or as a result of pressure. Radicular syndromes are particularly frequent. These are based on prolapsed disks or degenerative changes ... | 232,951 | [
-0.1976049,
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0.1074733,
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0.1102643,
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0.4523931,
0.1641308,
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0.118405,
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0.2208183,
0.114355,
0.0367713,
0.3076515,
-0.1217066,
0.06057309,
-0.0... |
[Influence of straw manuring on the biological activity of a lessivé chernozem (author's transl)]. | In a long-term experiment, the influence of straw manuring in spring and autumn on the biological activity of a lessive chernozem soil was examined. The quantity of carbon dioxide, evolved by the plots during May and June, showed an increase in soil respiration by straw manuring. Increasing amounts of nitrogen, given t... | 232,956 | [
-0.08346193,
0.3856976,
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0.1294167,
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0.1777396,
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-0.170866,
-0.01125832,
0.1300745,
0.1174366,
0.2354816,
0.1284371,
-0.123... |
Gel electrophoresis of rotavirus RNA derived from six different animal species. | Rotavirus RNA prepared from calf, pig, mouse, deer, foal and dog-adapted human isolates was compared using polyacrylamide gel electrophoresis. Reproducible differences in the RNA migration patterns were found between all isolates. There were 11 clearly resolved segments in the pig, mouse and foal samples. The calf rota... | 232,982 | [
-0.3970982,
-0.05949939,
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0.3015564,
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0.001987756,
0.07264528,
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0.09519358,
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0.4050912,
-0.1067077,
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-0.04310543,
-0.... |
Natural hypocholesterolemic agent: pectin plus ascorbic acid. | An addition of 5% citrus pectin and 0.5% ascorbic acid to high-fat diet of guinea pigs prevented total cholesterol accumulation in blood serum and the liver. Two groups of persons were given a preparation containing a daily dose of 15 g pectin and 450 mg ascorbic acid for 6 weeks. In 21 healthy persons with mild hyperc... | 233,013 | [
-0.007807011,
0.1807367,
-0.07926341,
0.04807857,
0.358806,
0.03729754,
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0.09702233,
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0.1771784,
0.443517,
0.06565795,
0.01782156,
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-0.7987088,
-0.003493201,
-0.03466148,
0.1185089,
0.1341799,
0.4307501,
-0.06309... |
Histochemistry of the post-resuscitation changes in the brain. | In 20 dogs, acid mucopolysaccharides, gangliosides, lysosomal enzymes and iontransport enzymes were investigated. Material was taken 2, 24 and 72 h after 15 min of clinical death due to electrotrauma. Changes in the post-resuscitation period indicated deterioration of transmembrane ion--metabolite transport in the brai... | 233,039 | [
-0.1468043,
-0.2654749,
0.00658218,
-0.2523885,
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0.3278707,
0.2635193,
0.3116161,
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-0.02408444,
0.06624229,
0.08775058,
-0.01559239,
0.03894101,
0.2865132,
-0.1745366... |
[Effect of chlorpropamide and of phenformin on isolated liver plasmatic membranes]. | Previous observations from this laboratory suggest that chlorpropamide and phenformin, two hypoglycemic drugs belonging to sulfonylureas and biguanides respectively, act on liver plasma membranes altering the activity of enzymes bound to plasma membrane as (Na+-K+)-ATPase. This enzyme, an integral membrane protein whic... | 233,070 | [
-0.1794162,
0.05489108,
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0.1183407,
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0.07778898,
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0.2251323,
0.2479566,
0.2836686,
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0.133834,
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0.1093768,
0.2829701,
-0.01754949,
-0.008241009,
-0.... |
[Eccrine poroma: its histogenesis and review of the literature]. | It has been done an analysis of a case of eccrine porome, based on the morphology, considering the actual tecnical publications on the matter. The morphogenesis of the formation of this nevoid tumor is established by the continuity between the main body of the tumor and the underneath eccrine sweat glands. These glands... | 233,110 | [
-0.2981014,
-0.4338786,
0.0460805,
0.04754857,
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0.001547279,
0.5003008,
0.5271987,
0.06993765,
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-0.2302476,
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-0.197973,
0.01421466,
-0.01855331,
-0.235056,
0.3431014,
-0.02802599,
-0.0869472... |
Role of intracellular Ca2+ sequestration in beta-adrenergic relaxation of a smooth muscle. | Various mechanisms have been proposed for beta-adrenergically mediated relaxation of smooth muscle. All theories suggest the involvement of cyclic AMP as a second messenger: beta-agonists stimulate adenylate cyclase which converts ATP to cyclic AMP and protein kinase, activated by cyclic AMP, is then thought to catalys... | 233,130 | [
-0.4322926,
-0.08417153,
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0.1157044,
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0.1247913,
0.1989345,
0.250792,
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-0.4335508,
-0.1381038,
-0.13287,
-0.07828291,
0.5377961,
0.2378078,
-0.1223608,
... |
Controlled synthesis of HBsAg in a differentiated human liver carcinoma-derived cell line. | A significant aspect of primary hepatic carcinoma in man is the high positive correlation of hepatocellular carcinoma with infection with hepatitis B virus (HBV)1. Analysis of the relationship between HBV infection and oncogenesis is difficult because natural infection with HBV is limited to man and experimental infect... | 233,137 | [
-0.04644698,
-0.3583485,
-0.3419579,
-0.06487417,
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0.0006234796,
0.3673781,
0.1021293,
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-0.2924103,
-0.003957699,
0.02098782,
-0.1308458,
0.2457892,
0.2608946,
0.1885217,
-0.... |
Isolation and characterization of antibodies to Clostridium perfringens epsilon toxin from hyperimmune horse serum. | Antibodies against epsilon toxin were isolated from hyperimmune horse serum by affinity chromatography. Purified epsilon prototoxin covalently bound to Affigel 202 was used as immunosorbent, and antibodies were eluted with 6.0 M guanidine chloride. In a single run 80 mg of antibody could be recovered from a 20 microlit... | 233,148 | [
-0.5088795,
0.09765874,
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0.1254201,
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0.1888804,
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0.1781649,
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0.5343077,
0.358655,
0.3227999,
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0.1841291,
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-0.05476385,
0.2998906,
0.301396,
-0.3194416,
0... |
Muscarinic supersensitivity: a possible model for the sleep disturbance of primary depression? | The sleep changes induced in normal volunteers following the administration of scopolamine on 3 consecutive mornings resemble many of the abnormalities observed in the sleep of patients with primary depression: increased sleep latency and reduced rapid eye movement (REM) latency, total sleep time, and sleep efficiency.... | 233,154 | [
0.09168432,
-0.1676415,
-0.3059016,
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0.2222134,
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0.1163181,
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0.1957048,
0.3041816,
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0.2566105,
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0.0140317,
-0.5526316,
0.1285888,
0.08040087,
-0.02981754,
-0.03601777,
-0.01176768,
-0.00842501... |
EEG sleep and affective psychoses: I. Schizoaffective disorders. | The sleep electroencephalogram (EEG) was studied in 41 depressed inpatients. EEG sleep records were compared for two diagnostic subgroups; patients with psychotic depression (n = 29) or with schizoaffective disorders (n = 12). As was true in the previous pilot study, no major EEG sleep variables distinguished the patie... | 233,156 | [
-0.1584555,
-0.02536271,
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0.2515888,
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0.4075317,
0.3318547,
-0.2289003,
-0.06797551,
0.006857883,
0.05023157... |
Dopamine-mediated behavior produced by the enkephalin analogue FK 33-824. | Intraperitoneal injection of FK 33-824 produced apomorphine-like stereotyped behavior in rats. Antagonism of this stereotypy by naloxone and neuroleptics suggests that FK 33-824 can activate opiate and dopamine receptors in the brain. Because increased dopaminergic neuronal activity is thought to be involved in schizop... | 233,159 | [
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-0.5259588,
-0.05284733,
0.1094961,
0.08854457,
-0.2109776,
0.1119053,
-0.191... |
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