title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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[Methods of treating the Itsenko-Cushing hypothalamo-hypophyseal syndrome]. | Studies of a group of patients with the Icenko-Cushing syndrome during the period of 6 months to 6 years permitted to establish that the treatment of the disease, irrespective of the etiology, is most effective when using preparations of gamma-amino-butyric acid, vegetotropic preparations and antidepressive drugs in co... | 325,970 | [
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Minerals in human teeth: differences between preindustrial and contemporary Hopi Indians. | Mineral elements in dentin from 17th century Hopis were compared with samples from contemporary Hopis living in the same geographic area. Less lead, zinc, and copper, and more strontium were found in the preindustrial teeth. Trace element levels in the contemporary Hopi teeth were similar to those in suburban Californi... | 326,020 | [
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Microscopic evaluation of enamel after debonding: clinical application. | Enamel surfaces were debonded by methods recommended in the literature and found to be problematic. A new method, not previously recommended, involving the use of a green rubber wheel followed by pumice or composite finishing paste was similarly examined and found to come closest to restoring the original, natural enam... | 326,060 | [
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T and B rosetting lymphocytes in the blood of smallpox patients. | The proportion of T and B cells in the peripheral blood of smallpox patients was determined. The average initial percentage of T cells was depressed (41 +/- 8.4%) in comparison with uninfected controls (65 +/- 7.6%), while the initial B cell counts averaged 26 +/- 11.4% and 28 +/- 5.1%, respectively. However, initial B... | 326,070 | [
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Minimally invasive technic for construction of a cervical esophageal conduit. | Most technics of cervical esophageal reconstruction involve extensive surgical dissection with its attendant hazards. The present report describes a simplified technic that causes minimal trauma to the patient. A partially deepithelialized, superficial skin tube is created without elevation of flaps and joined to the e... | 326,081 | [
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Treatment of a flail injury of the chest. A case report with consideration of the evolution of therapy. | A patient with flail-chest injury, and associated abdominal and musculo-skeletal trauma, required several modes of mechanical ventilation in the Surgical Intensive Care Unit Ventilator modalities included mechanical ventilation with positive end-expiratory pressure (PEEP) and intermittent mandatory ventilation (IMV) wi... | 326,088 | [
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Epidemic diarrhea at Crater Lake from enterotoxigenic Escherichia coli. A large waterborne outbreak. | In June and July 1975, Gastrointestinal illness occurred in more than 200 staff members and 2000 visitors to an American national park. In was characterized by prolonged diarrhea, cramps, nausea, and vomiting, lasted a median duration of 8 days, and was significantly associated with consumption of park water (P less th... | 326,116 | [
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Succession of Streptococcus bovis strains with differing bacteriophage sensitivities in the rumens of two fistulated sheep. | The bacteriophage sensitivity of the Streptococcus bovis population resident in the rumens of two fistulated sheep was monitored for 112 days. During this time, three changes in the bacteriophage sensitivity of S. bovis occurred in the absence of detectable bacteriophages. Identical changes in bacteriophage sensitivity... | 326,185 | [
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Ambient-temperature primary nonselective enrichment for isolation of Salmonella spp. from an estuarine environment. | A primary, nonselective, ambient-temperature enrichment procedure for isolation of Salmonella spp. is described. The procedure was superior to elevated-temperature selective enrichment for Salmonella when estuarine water samples were examined. Five Chesapeake Bay stations were monitored, over an 8-month period, for the... | 326,187 | [
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Amino acid profiles and presumptive nutritional assessment of single-cell protein from certain lactobacilli. | The amino acid profiles, modified essential amino acid (MEAA) indexes, and in vitro pepsin digestibilities were determined for single-cell protein (SCP) from certain industrially important lactobacilli. For the three parameters examined, substantial differences were seen between different Lactobacillus species and betw... | 326,190 | [
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Controlled trial of continuous positive airway pressure given by face mask for hyaline membrane disease. | A controlled trial of elective intervention with continuous positive airway pressure (CPAP) was performed on 24 infants with hyaline membrane disease whose arterial oxygen tension (Pao2) fell below 8kPa (60 mmHg) while they were breathing a fractional inspired oxygen concentration (F1O2) greater than 0.60. A face mask ... | 326,199 | [
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Trypanosomal antigen on macrophages cultivated in vitro with Trypanosoma (Schizotrypanum) dionisii. | The indirect fluorescent antibody test has demonstrated the presence of trypanosomal antigen on the surface of mouse peritoneal macrophages cultivated in vitro in the presence of Trypanosoma (Schizotrypanum) dionisii. | 326,206 | [
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Hypersensititivity of rats to anorectic agents after lesions in the ventromedial hypothalamus. | Anorectic agents such as d-amphetamine and fenfluramine showed a remarkably higher effect in rats with hyperphagia after lesioning the ventromedial hypothalamus. A persistence and even a further increase of the hypersensitivity to anorectics was observed in animals which, eight months after ventromedial hypothalamus-le... | 326,210 | [
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Bone marrow transplantation in patients with gold-induced marrow aplasia. | Aplastic anemia is a rare but usually fatal complication of gold salt therapy for rheumatoid arthritis. This report describes 3 patients who developed aplastic anemia while receiving gold salts, and a fourth patient who developed aplastic anemia after receiving gold and then cytotoxic agents. These patients failed to r... | 326,260 | [
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[Piprozoline in clinical trials (author's transl)]. | The tolerance and efficacy of ethyl (Z)-(3-ethyl-4-oxo-5-piperidino-thiazolidin-2-ylidene) acetate (piprozoline, Gö 919, Problin) were investigated in open and controlled clinical trials involving a total of 1545 patients and 1807 courses of therapy. The objective of this paper is to compare the experimental findings, ... | 326,261 | [
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The isolation and characterization of a bile ductule cell population from normal and bile-duct ligated rat livers. | The separation of bile ductule cells from Kupffer and sinusoidal endothelial cells in a suspension of non-parenchymal cells has been attempted. Bile duct ligation was performed so that a four-fold increase in the total number of non-parenchymal cells isolated from rat liver was attained and the proportions of both Kupf... | 326,290 | [
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Betamethasone valerate aerosol in the treatment of oral lichen planus. | Betamethasone valerate aerosol, given in doses of up to 800 microgram per day, was compared with placebo in a double-blind trial involving 23 patients with oral lichen planus. The majority of patients receiving the active aerosol noted improvement within the first 2 weeks of treatment and at 8 weeks the lesions had alm... | 326,295 | [
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The measurement of granulocyte kinetics. | Studies using 3H-TdR, DF32P or 51Cr have all contributed important information concerning neutrophil kinetics in normal and abnormal conditions. Recent evidence, however, suggests that DF32P underestimates, and 51Cr overestimates, the blood neutrophil T1/2 and that both isotopes overestimate the TBNP, compared with 3H-... | 326,297 | [
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Comparison of ocular hypotensive effects of acetazolamide and atenolol. | The ocular hypotensive effect of single oral doses of (a) atenolol (50 mg), (b) acetazolamide (500 mg), (c) atenolol (50 mg) and acetazolamide (500 mg) in combination, and (d) vehicle (inert tablets) were compared in 8 patients with glaucoma. In this single-dose, double-masked trial the combination was observed as most... | 326,302 | [
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Atenolol eye drops in glaucoma: a double-masked, controlled study. | Guttae atenolol 4% (Tenormin), a pure beta1-blocking (i.e., cardioselective) drug, produced a median overall fall of 5-6 mmHg (range 3-2 to 13-2 mmHg) in the first tonometrised eyes of 7 patients with open-angle glaucoma or ocular hypertension and 1 with closed-angle glaucoma (off any treatment for the whole of the day... | 326,303 | [
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A rapid fluorescent focus-inhibition test for determining the neutralizing-antibody response to lymphocytic choriomeningitis virus. | Levels of neutralizing antibody to lymphocytic choriomeningitis (LCM) virus in the sera of 66 infected persons were assayed by a rapid fluorescent focus-inhibition test (RFFIT). The test was more sensitive than the mouse-neutralization (MN) test and could be completed in less than 24 h. The RFFIT titers were compared w... | 326,357 | [
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Management of cardiac arrest: seven steps to survival. | Cardiac arrest is a common medical emergency. It usually occurs suddenly and results in irreversible brain damage unless prompt, effective treatment is instituted. One plan for dealing effectively with this emergency consists of seven steps of cardiopulmonary resuscitation: (1) establishing the diagnosis and deciding w... | 326,369 | [
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Prevention of congenital rubella. | The vaccine of choice for rubella vaccination is considered to be RA 27/3, based on frequency of side effects, duration of immunity, antigenic potential and rate of reinfection by wild virus. The most appropriate individuals to be vaccinated are prepubertal schoolgirls and susceptible members of other high-risk groups,... | 326,368 | [
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Conservative treatment of breast cancer. A trial in progress at the Cancer Institute of Milan. | The report describes a clinical trial on conservative surgery in progress at the National Cancer Institute of Milan, Italy. The randomized clinical trial compares radical mastectomy with a more conservative procedure consisting of mammary resection plus axillary dissection plus radiotherapy. The resection comprises an ... | 326,380 | [
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The pathogenesis of experimental bladder cancer. | The pathogenesis of signal morphological lesions of the urinary bladder induced in several species following administration of N-butyl-N-(4-hydroxybutyl)nitrosamine, bracken fern, or N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide is presented. Incidences of bladder neoplasia exceeding 80% were generated in the rat by eac... | 326,392 | [
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Some immunological considerations relevant to the study of human bladder cancer. | The likelihood that immunosurveillance, concomitant immunity, and immunodepression play a role in the development and spread of neoplasms of the urinary bladder is discussed. The circumstantial evidence for the existence of concomitant immunity to bladder cancer-associated antigens is briefly reviewed, and the implicat... | 326,394 | [
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Studies on the prostate and testis as immunologically privileged sites. | The immunology of the prostate and testis was studied by observing allograft survival in rats and by measuring humoral antibody and delayed hypersensitivity responses to tissue antigens in the rabbit. The delayed hypersensitivity response to tissue antigen(s) was definitely diminished in those organs without demonstrab... | 326,398 | [
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A historical review of the concept of the left ventricle as a pump. | Although the concept of the left ventricle as pump has gradually evolved over the past 2000 years, the "modern era" of our understanding began in the 1880's. Studies by Howell and Donaldson, using an isolated heart-lung preparation, provided insight into the inter-relationship between preload, afterload and contractili... | 326,412 | [
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0.06464287,
-0.1968185,
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-0.1198901,
-0.28117... |
Anomalous synthesis of ppGpp in growing cells. | In E. coli cells, accumulation of ppGpp is normally triggered by conditions that restrict the aminoacylation of tRNA or interfere with carbon/energy source metabolism; in both cases, the nucleotide's accumulation is associated with control of stable RNA synthesis and is generally believed to bring it about. We have fou... | 326,415 | [
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... |
Rheumatoid factor plaque-forming cells in rheumatoid synovial tissue. | Cells producing rheumatoid factor (RF) were readily detected in vitro by means of a haemolytic plaque assay system employing sheep erythrocytes (SRBC) sensitized with reduced and alkylated rabbit IgG anti-SRBC antibody as target cells. Rheumatoid factor-producing, plaque-forming cells (RF-PFC) were observed in all of t... | 326,444 | [
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0.06577486,
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Comparison of sodium meclofenamate and indomethacin in rheumatoid arthritis. | A double-blind crossover study was conducted in 15 patients with classical definite rheumatoid arthritis to compare the effect of sodium meclofenamate (300 mg daily) with placebo and indomethacin (100 mg daily). Each treatment was administered for 1 week to patients assigned at random to treatment sequences. The active... | 326,493 | [
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Sulpiride: evaluation of antipsychotic activity in schizophrenic patients. | Sulpiride is a new antipsychotic agent chemically different from recognized psychotropic compounds. The animal profile and the rapid urinary excretion without metabolism also distinguishes this drug from other neuroleptics. Previous studies have indicated therapeutic efficacy and few side effects. Sulpiride was evaluat... | 326,504 | [
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[Needle implantations--clinical report]. | In the last four years 27 patients with edentulous lower jaw were treated with implantation of rows of tantalum needles; 25 of them were followed up clinically and radiologically. After an average of two years and seven months where the success rate was found to be 72%. Reasons for failure were thought to be mistakes i... | 326,539 | [
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0.2294497... |
Ontogeny of the antibody-forming cell line in mice. III. The generation of mature anti-sheep red blood cell-specific B cells is antigen-dependent. | A role for antigen in the generation of fully mature splenic type B cells has been shown. In adoptive transfer experiments, cells from bone marrow or fetal liver required a longer period to give an anti-sheep red blood cell plaque-forming cell (PFC) response than those from spleen. This delay was not overcome by allowi... | 326,562 | [
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... |
The symbolic drawing of the family life space. | Several innovative techniques have been developed in the last ten years for facilitating meaningful communication and interaction among family members. These techniques serve the purpose of highlighting relatively stable patterns of verbal and nonverbal communication among family members and bring to the surface variou... | 326,575 | [
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0.1877285,
0.0418219... |
The management vf essential hypertension with once daily administration of timolol maleate and bendrofluazide. | A placebo controlled-blind study performed on new patients presenting with mild to moderate essential hypertension. A once daily combined dose of timolol maleate and bendrofluazide in a 4:1 ratio was administered ot each patient after a four week placebo period. The starting dose was timolol 10 mg and bendrofluazide 2-... | 326,593 | [
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0.3386407,
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0.1797885,
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Effect of cutaneous stimulation on the development of misdirected wiping reflexes in skin-grafted Discoglossus pictus. | The frog, Discoglossus pictus, has been studied with respect to wiping reflex behavior developing after skin rotations performed at larval stages. Misdirected wiping reflexes were obtained only from belly skin-grafts placed on the animals' back; back skin-grafts on the belly failed to elicit any misdirected limb moveme... | 326,603 | [
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0.3142101,
0.3773648,
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... |
C-peptide response to glucagon. A test for the residual beta-cell function in diabetes mellitus. | Pancreatic beta-cell secretory activity was measured in 17 patients with insulin-dependent diabetes mellitus of less than 19 months' duration and in 10 nondiabetic subjects by means of the peripheral plasma C-peptide response to 1 mg. of glucagon I.V. The C-peptide response to a meal was also measured in the diabetic p... | 326,604 | [
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0.2042973,
0.2598694,
0.2399765,
0.2399929,
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Immunohistochemical identification of lysozyme in intestinal lesions in ulcerative colitis and Crohn's disease. | Lysozyme (LZM) was identified in ulcerative colitis in granulocytes, monocytes, and macrophages of the intestinal lamina propria. In contrast with findings in normal colon or rectum, in ulcerative colitis LZM was also detected in some mucosal crypt cells and metaplastic Paneth cells. In both ulcerative colitis and Croh... | 326,636 | [
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0.2735052,
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0... |
Double-blind placebo-controlled study of loperamide (Imodium) in chronic diarrhoea caused by ileocolic disease or resection. | Loperamide (R 18 553) was compared with placebo in a double-blind crossover study of 21 patients with chronic diarrhoea caused by ileocolic disease or resection. Eighteen patients completed the trial. At a median daily dose of 6 mg the new antidiarrhoeal preparation was found to be superior to placebo in controlling ch... | 326,642 | [
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0.03011656,
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0.3687183,
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Split-dose and liquid-holding recovery after X-irradiation on diploid yeast Saccharomyces cerevisiae. I. Dependence on growth-phase. | Liquid-holding recovery (LHR) and the sparing effect of dose fractionation were investigated with 100 kVp-X-rays in diploid yeast from exponential and stationary phase. Exponential cells showed prompt and complete split-dose recovery. The ability to undergo LHR remained constant during 2-5 hours incubation after the fi... | 326,710 | [
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0.1582996,
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0.2346438,
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... |
Significance of catheter tip cultures. | Sixty-three patients were studied after renal transplantation to determine whether infection associated with use of the urethral catheter could be diagnosed reliably with catheter tip cultures. Catheter tip cultures correlated poorly with urine cultures aspirated from the catheter and follow-up voided urine cultures. P... | 326,720 | [
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0.1376455,
... |
Serologic study of specimens with borderline FTA-ABS test reactivity. | The treponemal group-specific absorbed fluorescent antibody test (FTA-ABS) does not yield clearly positive or negative results in all instances. This study was designed to analyze those sera showing borderline reactivity, in order to determine whether additional tests may help to resolve serodiagnostic problem cases. F... | 326,729 | [
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Molecular events associated with induction of arginase in Saccharomyces cerevisiae. | Arginase, the enzyme responsible for arginine degradation in Saccharomyces cerevisiae, is an inducible protein whose inhibition of ornithine carbamoyl-transferase has been studied extensively. Mutant strains defective in the normal regulation of arginase production have also been isolated. However, in spite of these st... | 326,758 | [
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Studies of the lipid phase transitions of Escherichia coli by high sensitivity differential scanning calorimetry. | High sensitivity adiabatic differential scanning calorimetry was performed on lipids, membrane vesicles, and whole cells of Escherichia coli enriched in particular unsaturated fatty acids by genetic means. Information concerning the shape of the transition is discussed. Transitions with an asymmetric shape reminiscient... | 326,779 | [
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Gas-liquid chromatography of fecal neutral steriods. | A method is described for the analysis of fecal neutral steriods with a dual-column gas-liquid chromatography (GLC) system. After saponification of the fecal slurry, the neutral steroids were extracted with hexane. The GLC separation of the compounds and quantitation were achieved by simultaneous injection of the deriv... | 326,802 | [
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... |
Template method for the fluorescent-antibody technique. | An easily constructed and inexpensive template has been developed, which enables the fluorescent-antibody technique to be applied to serial dilutions and allows 18 assays on a single microscope slide. | 326,808 | [
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0.3541086,
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... |
The role of activated accessory cells in preventing immunosuppression by hydrocortisone. | The generation of humoral immunity in vitro by normal and antigen-primed mouse spleen cells was suppressed by in vitro treatment with hydrocortisone. Functions of normal and antigen-activated helper T lymphocytes and of accessory cells were inhibited by the corticosteroids. Spleen cells cultured overnight in medium con... | 326,953 | [
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0.3278351,
0.06515255,
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-0.08876555... |
Erythrocyte membrane-associated immunoglobulins during malaria infection of mice. | Immunoglobulin (Ig) is associated with erythrocyte membranes during infection of A/J mice with Plasmodium berghei. It was detected by agglutination of the cells with rabbit antibodies to mouse IgG and by a radioimmunoassay with 125I-labelled rabbit antibodies to mouse IgG. As shown by the degree of agglutination and of... | 326,956 | [
-0.2138117,
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0.141979,
0.1318581,
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-0.250... |
Radioimmunoassay of IgG and IgM rheumatoid factors reacting with human IgG. | Although IgG rheumatoid factor may play a central role in the pathogenesis of rheumatoid arthritis, previously there have been no precise methods for its specific measurement in serum and synovial fluid. This paper describes a solid phase radioimmunoassay for the independent quantification of IgM and IgG rheumatoid fac... | 326,961 | [
0.03915944,
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Problems with radiolabelling egg albumin for the Farr ammonium sulphate technique for antibody estimation. | High concentrations of passive haemagglutinating antibodies were raised in sheep immunised with egg albumin (Ea) in Feund's adjuvant. Further attempts to study the antigen binding capacities and avidities of these antisera by the Farr ammonium sulphate technique were hindered by unsuccessful attempts to label Ea with 1... | 326,967 | [
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0.04385446,
0.03696403,
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... |
The detection of platelet isoantibodies by membrane immunofluorescence. | A membrane ummunofluorescence test for the detection of platelet isoantibodies is described. Gel filtration of the incubation mixture was incorporated in the procedure and proved effective for the removal of serum proteins from the platelet suspension. With this technique isoantibodies were found in the serum of 13 out... | 326,998 | [
-0.07085507,
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0.3834731,
0.6042834,
0.1766945,
0.0207791... |
Pathogenesis of Shigella diarrhea. VII. Evidence for a cell membrane toxin receptor involving beta1 leads to 4-linked N-acetyl-D-glucosamine oligomers. | The binding of ShigeUa dysenteriae 1 cytotoxin to HeLa cells in culture and to isolated rat liver cell membranes was studied by means of an indirect consumption assay of toxicity from the medium, or by determination of cytotoxicity to the HeLa cell monolayer. Both liver cell membranes and HeLa cells removed toxicity fr... | 327,017 | [
0.1027318,
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0.1558167,
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0.04927091,
0.007040014,
0.2485979,
0.1942385,
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0... |
Rosetting and other reactions of the Reed-Sternberg cell. | Clustering of lymphocytes around Reed-Sternberg cells was noticed in single cell suspensions made from viable Hodgkin's lymphoid tissue. Cytocentrifugation of the suspension showed that clustering also occurred around a smaller cell type, thought to be the precursor of the classical Reed-Sternberg cell. Time-lapse cine... | 327,044 | [
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0.2145231,
0.5171587,
0.3036475,
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0.2... |
Group B beta-hemolytic streptococci analysis of 242 isolations. | Group B beta-hemolytic streptococci (GBS) were isolated from 242 patients at Howard University Hospital during a seven-month period. The source of the majority, 236, was the genital tract of women. In six instances, the organism was cultured from various sites in neonates born of mothers harboring GBS in their birth ca... | 327,083 | [
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0.3735037,
0.4142464,
0.103617... |
Adult respiratory distress syndrome (ARDS), sepsis, and extracorporeal membrane oxygenation (ECMO). | This report presents data obtained in the care of 830 patients requiring assisted ventilation. When these patients were divided into groups by the severity of their respiratory failure as defined by the duration of ventilatory assistance (greater than 48 hours, less than 48 hours) and level of positive end expiratory p... | 327,084 | [
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0.1747599,
0.01421568,
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0.04081786,
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0.... |
Commentary on the immunobiology of bladder cancer. | This review is an attempt to integrate the conflicting studies that constitute the literature on immunobiology of bladder cancer and to indicate areas that need further investigation. It is clear that immune reactivity directed at antigens expressed on bladder cancer cells and general host immunologic competence declin... | 327,096 | [
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Urinary fistulas after renal transplantation. | Urinary fistulas developed in 18 of 200 renal transplants (9 per cent). Twelve fistulas healed after conservative treatment and 6 were repaired by an operation. Our repair technique included constructing a bladder flap for patching, incorporating the fistula into the bladder and suturing the bladder directly to the ren... | 327,097 | [
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T lymphocyte rosette formation after major burns. | The ability of lymphocytes to form rosettes with sheep erythrocytes was studied in the acute burn period to quantitate T lymphocytes. Seventeen adult patients with burns of greater than 15% body surface area were studied serially and compared to normal controls. The absolute number of total rosette-forming cells (RFC) ... | 327,110 | [
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[Concentration of C-peptide in correlation to kidney function (author's transl)]. | Recently, the radioimmunological determination of C-peptide came into interest because of the jugdement of the remaining function of the islet apparatus in insulin-dependent diabetics. As the degradation of C-peptide preferably takes place in the kidney we performed an intravenous glucose load in 32 patients with kidne... | 327,148 | [
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Investigation of the histocompatibility of the NYA:NYLAR mouse colony by skin grafting. | The histocompatibility status of the Nya:NYLAR mouse colony was studied by exchange of skin grafts between female mice. The colony had been divided into two portions since 1962, a larger, outbred stock (Nya:NYLAR), and a smaller, inbred strain (NYLR/Nya). The results of skin graft exchanges between mice of the inbred s... | 327,154 | [
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Faculty of Anaesthetists, Royal Australasian College of Surgeons. Foundation and progress. | The Faculty of Anaesthetists, Royal Australasian College of Surgeons, was inaugurated in 1952. Events leading to its foundation are described, together with the steps of evolution. An evaluation of its present-day relations with the Australian Society of Anaesthetists and the Royal Australasian College of Surgeons is m... | 327,233 | [
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A specialized transducing lambda phage carrying the Escherichia coli genes for phenylalanyl-tRNA synthetase. | A lambda phage has been isolated which specifically transduces the Escherichia coli pheS and pheT genes coding for the alpha and beta subunits of the phenylalanyl-tRNA synthetase (PRS). This phage transduces with high frequency (i) several temperature-sensitive PRS mutants to thermoresistance and (ii) a p-fluorophenyla... | 327,276 | [
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Mapping of mutation tsm-8 with respect to transfer RNA genes on the mitochondrial DNA of Saccharomyces cerevisiae. | A precise localization of the tsm-8 mutation in relation to the transfer RNA genes has been attempted by rho- deletion analysis. The data show that the tsm-8 mutation is in close proximity to the isoleucyl transfer RNA gene. However, it is not yet possible to decide whether the tsm-8 mutation is within this transfer RN... | 327,285 | [
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[Do modern surgical methods in the treatment of retinal detachment represent progress?]. | The results of plombage and encircling procedures in 417 eyes operated on for retinal detachment are compared with the rate of success obtained by lamellar or penetrating scleral resection in the past. | 327,290 | [
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The use of rec-bacteria for testing of carcinogenic substances. | A series of rec-Escherichia coli strains were tested for their sensitivity to four known carcinogenic compounds by examination of a zone of inhibited bacterial growth around a central well containing the test chemical. The mutants recA-, recB-, recC-, and recA- recB- recC- were all more sensitive to the mutagens than t... | 327,303 | [
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Mutagenicity of anti-cancer nitrobenzofuroxans. | Anti-leukaemically active benzofuroxans were tested for mutagenicity in Salmonella typhimurium. Mutagenicity was not found to be correlated to the previously established anti-leukaemic activity. One anti-leukaemically inactive compound after exposure to liver microsomal enzymes proved the most mutagenic of the derivati... | 327,305 | [
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[Psychiatry and mental health in the Institutp de Seguridad Social para los Trabajadores del Estado. Philosophy of its development]. | In 1972, prepaid medical care for government employees provided by their social security institute, ISSSTE, was reorganized. A division of planning and technical standards was established, within which a Department of Psychiatry was included. Psychiatric care was restructured at three levels: psychiatric hospital, psyc... | 327,343 | [
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Licensure of foreign medical graduates: an historical perspective. | Today, one out of five practicing physicians in the U.S. is a graduate of a foreign medical school. The sixfold growth in their number over the past two decades results from national policy; but the place and conditions of practice have been controlled by state governments. The several states have used their jurisdicti... | 327,346 | [
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Staged excision and reconstruction of extensive facial-orbital tumors. | Extensive facial-orbital tumors are basal cell carcinomas which are exceptionally difficult to treat by conventional therapy because of: (1) skin involvement of more than one square inch of the eyelids of face; (2) fixation to bone or periosteum at the orbital rim; and (3) extension onto the inner surface of the eyelid... | 327,373 | [
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Adaptive training and individual differences in perception. | Four types of training techniques were compared in the training of a perceptual concept-formation task. Adaptive training, a technique in which one parameter in the learning situation is varied so that the difficulty of a learning task remains constant for that individual, was compared to three intermediate approaches ... | 327,433 | [
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The illness of Ludwig II of Bavaria. | It has been argued by many biographers of King Ludwig II that he was not mentally ill but simply labelled mad as part of a conspiracy to remove him from the throne. The evidence for his mental disorder is reviewed and the conclusion drawn that he was probably suffering from a schizophrenic illness of some twenty years ... | 327,496 | [
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The serological relationship of a British Theileria with other Theileria species using the indirect fluorescent antibody test. | Antisera and antigens of a Theileria species isolated from British cattle were compared with those of six strains of Theileria mutans from geographically separated areas in East and South Africa, using the indirect fluorescent antibody (IFA) test. It was found that the British Theileria species did not react in the IFA... | 327,522 | [
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Mechanism of carbon isotope fractionation associated with lipid synthesis. | The low carbon-13/carbon-12 ratio of lipids is shown to result from isotopic fractionation during the oxidation of pyruvate to acetyl coenzyme A. In vitro analysis of the kinetic isotope effects of this reaction indicates that there will be a large, temperature-dependent difference in the carbon-13/carbon-12 ratio betw... | 327,543 | [
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Mutagenic activity of quercetin and related compounds. | The mutagenic activities of several flavonoids and flavonoid metabolites were examined by means of Salmonella typhimurium mutants that reveal base-pair substitution and frameshift mutagens. Of the compounds tested (naringin, rutin, neohesperetin, hesperetin, dihydroquercetin, quercetin, quercetin pentaacetate, permethy... | 327,550 | [
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... |
[Pathology of the malignant ovarian tumours (author's transl)]. | A review of the principles of histological classification of the malignant ovarian tumours is given. In the center of the discussion figure the tumours originating from the surface epithelium, which make up the majority of ovarian tumours. In dependence on the tumour type they differ in tendency to spread and in progno... | 327,624 | [
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... |
[Extravesical antirefluxplasty (author's transl)]. | The indications and the detailed technique of extravesical antirefluxplasty are presented. Realized on 409 ureters (247 cases), extravesical antirefluxplasty has been successful in 95% of these cases. The failures, i.e., obstructions (1,5%) and persistent reflux (3%), are analized. | 327,648 | [
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[Intraluminal balloon occlusion of the renal artery: clinical applications and observations (author's transl)]. | A method permitting percutaneous catheterization and temporary balloon occlusion of the human renal artery with a 5-F-Swan-Ganz-Catheter is presented. When properly performed, the arterial occlusion is reliable, low in complications, and less traumatizing to the vessel than external clamp occlusion. The technique was e... | 327,649 | [
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0.6... |
Action of oral and parenteral bethanechol on decompensated bladder. | A double blind balanced Latin-square study was conducted on 20 adult patients with decompensated bladders to determine the relative effectiveness of oral and parenteral bethanechol chloride (Urecholine) on the stretch response of bladder muscle. Detrusor reaction was measured by modified cystometry. Five mg. of subcuta... | 327,652 | [
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0.3132... |
Evaluation of the indirect fluorescent antibody test for Babesia major and Theileria mutans in Britain. | Use of the indirect fluorescent antibody (IFA) tests is described to detect antibodies to Theileria mutans and Babesia major in the sera of infected cattle. When antisera against T mutans and B major were tested against homologous antigens high antibody titres were recorded: when they were tested against each other or ... | 327,676 | [
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... |
[Early symptoms of hyperparathyroidism in nephropathies]. | The development of an autonomous (tertiary) hyperparathyroidism in patients with renal diseases must clinically be taken into consideration, when by therapeutic measures the causes of a compensatory overfunction of the parathyroid glands were excluded, but the symptoms of a hyperparathyroidism continue or even increase... | 327,710 | [
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-0.2461... |
A comparison between placebo, pizotifen and 1-isopropyl-3-hydroxy-5-semicarbazono-6-oxo-2.3.5.6-tetrahydroindol (Divascan) in migraine prophylaxis. | The effects and side-effects in migraine prophylaxis of placebo, Divascan (1-isopropylnoradrenochrome--5--monosemicarbazone) and pizotifen were compared in a double-blind cross-over study. The dosage was for Divascan 15 mg a day and for pizotifen 3 mg a day. Data from the last 6 weeks of each test period of 8 weeks wer... | 327,746 | [
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0.... |
A modification of the Guiot-Gillingham stereotaxic frame to allow of angular insertion. | A method of modification of the Guior-Gillingham Stereotaxic frame is described, which will allow of angular insertion of a leucotome or electrode. In our experience, this has prevented the complication of radiation damage and hemianopia and it also permits greater flexibility in the operative approach to structures at... | 327,759 | [
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0.... |
Location of food consumption and travelers' diarrhea. | Daily food histories for one month were obtained in summer, 1975, from students attending a Mexican university to determine the influence of food consumption on the development and etiology of diarrhea. In newly-arrived students from the U.S. who ate half or more of their meals in the school cafeteria and public restau... | 327,798 | [
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-0.4527358,
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-0.1225218,
-0.03113365,
-0.1583944,
-0.3023731,
-0.4380513,
0.231516,
-0.0912473... |
Echocardiography in congenital heart disease. | The utility of echocardiography in the evaluation of congenital cardiac disease is well established. The following discussion will be devoted to the application of single dimensional equipment in the assessment of selected congenital defects which will include secundum atrial defects, endocardial cushion defects, tetra... | 327,804 | [
-0.2906725,
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0.3798361,
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0.04418353,
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Collection of a clean voided urine specimen: a comparison among spoken, written, and computer-based instructions. | In an effort to compare different methods of instructing patients, 99 women 18-25 years of age were given computer, spoken, weitten, or no instructions for the collection of a clean voided urine specimen. The group who received computer instructions was the most uniform in its performance (P less than 0.002, F-test) an... | 327,837 | [
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0.3402119,
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0.1267429,
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-0.4139732,
... |
Flow rates from an intermittent positive pressure breathing-anesthetic delivery apparatus for horses. | Inspiratory flow rates were measured and compared in an equine intermittent positive pressure breathing-anesthesia delivery apparatus powered by a positive phase ventilator, a positive-negative phase ventilator, and a modified positive phase ventilator with automatic flow acceleration at driving pressures of 2,600, 4,4... | 327,874 | [
-0.2492702,
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0.2228449,
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0.058164... |
[The relationship between the degree of dissemination of pharyngolaryngeal tumours and immunological changes (author's transl)]. | An investigation was carried out on 34 patients with malignant pharyngolaryngeal tumours which had been operated on, microscopic changes in the regional ganglia (sinusal histocytosis, hypertrophy of the germinal centres, the paracortical area, the number of pyroninophilic plasmocytes, the behaviour of the mastocytes) a... | 327,897 | [
-0.07898493,
-0.5580192,
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-0.0270132,
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0.1506315,
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0.03601978,
0.04890536,
0.05239106,
0.493412,
0.3926944,
0.1269308,
0.2563111... |
[Action of tetracyclines on the pseudotuberculosis microbe in vitro experiments and their effectiveness in experimental pseudotuberculosis in white mice]. | 227 out of 228 strains of pseudotuberculosis microbes studied in vitro proved to be sensitive to tetracyclines. The MIC of tetracycline and morphocycline ranged within 0.25--25 gamma/ml. The MIC of chlortetracycline and oxytetracycline was somewhat lower, i. e. 1--50 gamma/ml. When administered intramuscularly all the ... | 327,916 | [
0.004531645,
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0.02254527,
-0.2682656,
0.08241781,
0.04767071,
-0.5708605,
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0.3000718,
0.4099161,
0.3270322,
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0.2886463,
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0.3668146,
0.2561074,
0.1200661,
0.07399753,
... |
First-rank symptoms of schizophrenia in Schneider-oriented German centers. | First-rank symptoms of schizophrenia, such as thought insertion, thought broadcasting, "made" volition, and delusional perception, were introduced for purposes of diagnosis into a German university clinic. Such "Schneiderian" criteria were evaluated in 210 case records. Ratings employed formal definitions. Of 210 recor... | 327,966 | [
-0.2384752,
0.1386244,
0.1357006,
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0.03020713,
0.2963221,
0.05445923,
-0.05384717,
0.198256,
0.6031436,
0.01431522,
0.... |
Cell-mediated immunity in experimental syphilis in rabbits. | The development of cell-mediated immunity was studied in rabbits: a) experimentally injected with T. pallidum, and b) artificially immunized with nonviable T. pallidum. The macrophage migration inhibition test (MMI test) using ultrasonicate of T. pallidum as antigen was employed to demonstrate this type of immunologic ... | 327,968 | [
-0.1100037,
0.01087057,
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0.2817182,
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-0.1267141,
0.07033467,
0.1431769,
-0.3646061,
0.2322513,
0.140379,
-0.05794754,
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-0.04399994,
-0.30514,
0.2996395,
-0.5682121,
0.1433344,
0.3699845,
0.04472612,
0.1465993,
-... |
Characterization of lymphocyte E rosette inhibitory factor in sera from tuberculous patients. | Rosette inhibitory factor (RIF) in serum of patients suffering from active pulmonary tuberculosis, after in vitro contact with lymphocytes from healthy subjects, inhibits spontaneous rosette formation of these lymphocytes with sheep red blood cells (SRBC). RIF is not a C-reactive protein. By the use of chromatography o... | 327,969 | [
-0.05055494,
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0.1103502,
0.5007094,
0.1476894,
0.1392751,
-0.05786738,
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John and William Hunter on aneurysms. | John and William Hunter made important contributions to vascular surgery that have prevailed until today. Their studies of aneurysm formation, pathology, and treatment laid the foundation for many modern surgical concepts. In the Great Wind mill School of Anatomy, and subsequently at St George's Hospital, London, the H... | 327,974 | [
0.07013237,
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0.09859997,
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0.07044201,
0.08519747,
0.2585302,
0.3567072,
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0.2079228,
0.3091588,
0.1117298,
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0.0826138,
0.04647674,
-0.2482596,... |
Baclofen, a new antispastic drug. A controlled, multicenter trial in patients with multiple sclerosis. | A double-blind, five-week, multicenter trial was conducted to compare the effect of baclofen, a unique amino acid derivative, with that of placebo in the treatment of 106 patients with spasticity secondary to multiple sclerosis. A spasticity assessment method that included a neurological examination, physicians' clinic... | 327,987 | [
0.07036161,
0.1280406,
0.125289,
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0.01028772,
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0.1000787,
0.1055517,
0.2515135,
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0.1263918,
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0.183183,
-0.3828014,
0.08359898,
-0.06821299,
0.1523213,
0.02151473,
0.0... |
Proplast in the middle ear and oval window of cats. | Poly(tetrafluoroethylene) carbon fiber implant material (Proplast), an all-plastic material, was evaluated for use in otologic surgery. Response to the implant was studied in the middle ear and vestibule of 14 cats by placing the Proplast in the oval window after stapedectomy. After a one year follow-up, it appears tha... | 327,990 | [
-0.3036853,
0.09306822,
0.05773209,
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0.467337,
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0.4599492,
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-0.1097798,
0.1060172,
0.1192439,
0.06043144,
... |
Activation of selenate by adenosine 5'-triphosphate sulphurylase from Saccharomyces cerevisiae. | In the presence of ATP and Mg2+, ATP sulphurylase from Saccharomyces cerevisiae catalysed the conversion of selenate into a compound with the electrophoretic and acid-lability properties of adenosine 5'-sulphatophosphate. Structural characterization, involving extensive purification of adenosine 5'-selenophosphate, pro... | 328,009 | [
-0.2900804,
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0.2577668,
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0.1827978,
0.4624552,
0.07417043,
-0.07488123,
0... |
Haemodynamic effects of salbutamol and nitroprusside after cardiac surgery. | The haemodynamic effects of a continuous intravenous infusion of salbutamol (15 to 30 microgram/min) and nitroprusside (50 to 100 microgram/min) were compared in 9 patients after cardiac surgical operations. The mean falls in left atrial pressure and systemic vascular resistance were similar with the two drugs but salb... | 328,027 | [
-0.2686231,
-0.1475509,
-0.8217832,
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0.002026591,
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-0.329074,
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0.03058446,
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0.2621896,
0.2334314,
0.1829451,
0.05301088... |
The effect of temperature on concanavalin A-mediated agglutination of cells with rigid receptors. | The agglutination of a yeast, Candida albicans, by concanavalin A has been described. The agglutination was cell-number dependent. Prolonged incubation (60 min) was needed to reach maximum agglutination at 37 degrees C. The rate but not the extent of agglutination was temperature dependent. The dimeric forms of concana... | 328,040 | [
0.3453468,
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0.2648176,
0.1270422,
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0.1918039,
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0.05310798,
0.1411408,
0.3310733,
0.4049088,
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0... |
An NMR approach to tRNA tertiary structure in solution. | Atomic coordinates of E. Coli tRNA1Val have been generated from the X-ray crystal structure of Yeast tRNAPhe by base substitution followed by idealization... | 328,065 | [
-0.09388822,
0.1508199,
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0.1572259,
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-0.06136468,
0.2120391,
0.1976487,
-0.1084... |
Determination of continuing medical education needs of clinicians from a literature search study. Part II. Questionnaire results. | Part II of this study of the needs of clinicians for continuing medical education (CME) examines the results of a questionnaire sent of Oklahoma physicians to determine if they would request formal CME courses in the same subject areas in which they had previously requested in formation from librarians. The degree of c... | 328,093 | [
-0.008657936,
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0.1870787,
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-0.1711134,
-0.07112531,
-0.1922163,
0.2035381,
0.192498,
-0.0914482,
0.1401722,
... |
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