title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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[Toxoplasmosis and contact with animals: study of 390 cases]. | Three hundred and ninety patients with suspected toxoplasmosis due to their contact with animales--they owned them, or work with them--are studied. The great significance of this way of acquiring the disease is stated. Every patient had a complement fixation test and an intradermal reaction test with toxoplasmine. An 8... | 354,648 | [
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A possible combination of hypoxic cell sensitizer with an oxic protector: implications for radiotherapy. | This paper discusses the results of experiments using γ-rays and a hypoxic sensitizer metronidazole (MET) and also a well-known protector, mercaptoethylamine (MEA), individually and in combination, on the survival of the yeast S. cerevisiae BZ 34. MET (5mM) gave a hypoxic enhancement ratio (ER) of 1·3. MEA (5mM, 10mM) ... | 354,671 | [
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Escherichia coli infection in mice and impaired fetal development. | Investigations were undertaken, using the mouse as an animal model, to study the effect of Escherichia coli on fetal development. The i.v. injection of 7.5 X 10(6) bacteria, originally obtained from a suspected case of human pyelonephritis, caused only a mild and transient disturbance of maternal health but caused seve... | 354,680 | [
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Group B streptococcal infection in a maternity unit. | Neonatal infection due to Group B streptococci is described in a maternity unit. Six babies were affected and two died. Three of the babies were born at term, and weighed more than 2.5 kg. Tachypnoea was the earliest clinical sign in each case, and we suggest that newborn infants with persistent tachypnoea and evidence... | 354,686 | [
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Initiation of enzymatic DNA synthesis by yeast RNA polymerase I. | In vitro DNA synthesis by yeast DNA polymerase I can be initiated by partially purified yeast RNA polymerases in the presence or absence of rNTPs. Homogeneous yeast RNA polymerase I initiates DNA synthesis by yeast DNA polymerase I on single-stranded DNA templates only in the presence of all four rNTPs. A protein capab... | 354,689 | [
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Cytogenetic evidence for recurrence of acute myelogenous leukemia after allogeneic bone marrow transplantation in donor hematopoietic cells. | A 22-yr-old man with acute myelocytic leukemia received a bone marrow transplant from a genotypically HLA-identical female sibling after cyclophosphamide preparation. He remained in complete remission for 18 mo, when he developed a chloroma in the perineum. The chloroma was treated with local radiotherapy. The chloroma... | 354,703 | [
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Treatment of acute leukaemia in adults. | Although progress in the treatment of adult acute leukaemia has been much less dramatic than that which has occurred in the management of children with ALL, it should be clear from this progress report that significant strides have recently been made in the treatment of both adult ANLL and ALL that are of real benefit ... | 354,832 | [
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Effect of benzopyranoperidine, a delta-9-THC congener, on pain. | In a double-blind, 5-way crossover designed study, single doses of placebo, 2 doses of codeine sulfate (60 and 120 mg), and 2 doses of benzopyranoperidine (2 and 4 mg) were administered orally to 35 patients who required analgesics for chronic pain due to malignancies. Benzopyranopyridine is an analogue of delta-9-tetr... | 354,840 | [
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Neonatal assessment procedures: a historical review. | A historical review of neonatal assessment procedures is presented to demonstrate the trends in advancement of the field and attempts toward collaboration of medicine and psychology in contributions to the area. The literature suggests that the medically oriented neurological examinations have continued to be altered ... | 354,897 | [
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[Cardiotoxicity of mianserin, an antidepressant (author's transl)]. | The effect of mianserin on cardiac function was investigated on 60 adults with known heart disease, the drug previously having been shown not to influence the action of phenprocoumon. After satisfactory anticoagulation had been established, all patients were given additionally two different dosage regimens of mianserin... | 354,916 | [
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Effects of central cortical EEG feedback training on incidence of poorly controlled seizures. | This study examined the clinical effects of central cortical EEG feedback training in 8 patients with poorly controlled seizures. After base-line recordings, patients were trained in the laboratory and then initiated on a double or triple crossover design using portable equipment at home, with bimonthly laboratory test... | 354,919 | [
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Effects of slow intravenous administration of endotoxin on blood cells and coagulation in dogs. | Endotoxin shock was induced in dogs by slow administration of a lethal dose of Escherichia coli endotoxin. During the 3-hour infusion period a state of disseminated intravascular coagulation (DIC) was noted. The drop in platelets and leukocytes was the most rapid and pronounced effect of the infusion, while consumption... | 354,940 | [
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Roentgen manifestations of radiation injury to the gastrointestinal tract. | Radiation injury of the gastrointestinal tract requires a minimum dose of 4200 to 4500 rads. The symptoms and signs of radiation injury usually appear within 6 to 24 months following therapy. The radiation induced changes include mucosal atrophy and ulceration associated with an obliterative endarteritis in the support... | 355,048 | [
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[Gene relA function in the expression of amino acid operons. I. Effect of the allelic state of gene relA on phenotypic manifestations of auxotrophic threonine and isoleucine mutations in Escherichia coli K-12]. | The substitution of the relA gene mutant allele with wild type allele of this gene in strictly auxotrophic strain of Escherichia coli K-12 GT25, carrying thr B1007 mitation, results in the appearance of the partial dependence of the bacterial growth upon threonine. On the other hand, the introduction of relA mutation i... | 355,056 | [
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Alpha-1-antitrypsin deficiency: a biological enigma. | The association of certain forms of liver disease and a deficiency of alpha-1-antitrypsin is an observation which raises the possibility that other forms of liver disease ultimately will be found to have as their proximate cause a defined metabolic aberration, which may in turn be inherited. Although alpha-1-antitrypsi... | 355,063 | [
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Regulation of the immune response in autoimmune NZB/NZW F1 mice. II. Age dependent release of suppressive factors from spleen cells. | Supressor cells in the spleens of overtly autoimmune NZB X NZW (B/W) mice, but not age matched normal strain mice, were shown to release a small, less than 20,000 Dalton factor which inhibited early events in the anti-SRBC PFC response and the mitogenic response. This splenic inhibitory factor (SIF) was (i) stable on h... | 355,117 | [
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Casein-induced experimental amyloidosis. IX. Alterations in marrow dependent function. | CBA/J mice receiving multiple injections of sodium caseinate (CAS) or bovine serum albumin (BSA) were assayed for marrow dependent functions by measuring their ability (i) to reject bone marrow allografts and (ii) to resist Friend virus (FV)-induced suppression of lymphocyte mitogenesis. Mice that developed amyloidosis... | 355,124 | [
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Autonomic function in hemodialyzed patients. | The authors have studied the autonomic function in a group of 34 regular hemodialyzed patients and in a group of 24 normal volunteers with simple, non-invasive and repeteable techniques. To evaluate autonomic function Valsalva manoeuvre, cold pressor test, mental stress test, tilt test, diving reflex test, systolic-tim... | 355,149 | [
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Ex-vivo removal of mammalian immunoglobulin G: method and immunological alterations. | We have described a clinically feasible method capable of rapidly and repeatedly removing mammalian IgG extracorporeally by adsorption onto heat-killed, formalin-stabilized Staphylococcus aureus Cowan-I. In dogs, 2-13 grams of IgG were removed in 60-70 minutes, lowering the serum concentration of IgG by 30-70 percent. ... | 355,150 | [
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Pituitary insufficiency following head injury. | A 32-year-old man developed panhypopituitarism and diabetes insipidus shortly after sustaining a head injury. Hormonal investigation showed that basal prolactin levels were moderately elevated the first two years after the accident, but later returned to normal. There was no rise in prolactin after administration on ch... | 355,206 | [
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Evaluation of an office method of detecting bacteriuria. | Although catheter-associated UTI continues to be the leading cause of nosocomial infection, epidemiological investigation of catheter use in many hospitals may be precluded by the reluctance of the laboratory to process the large number of urine cultures. We have evaluated the use by Nurse Epidemiologists of Bacturcult... | 355,210 | [
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Pathways of mutagenesis and repair in Escherichia coli exposed to low levels of simple alkylating agents. | Mutagenesis by simple alkylating agents is thought to occur by either a lexA+-dependent process called error-prone repair or a lex-independent process often attributed to mispairing during replication. We show here that error-prone repair is responsible for the majority of mutants formed after a large dose of alkylatin... | 355,228 | [
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Tri-calcium phosphate as a bone substitute. | Strong porous tri-calcium phosphate ceramic has been fabricated, and investigated as a bone implant material. No foreign body reaction was observed, while osteoclastic activity was shown to be involved in biodegradation. Bone mineral was deposited directly onto the surface of the ceramic implant. | 355,245 | [
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Localization of actin in Dictyostelium amebas by immunofluorescence. | Antibody prepared against avian smooth muscle actin has been used to localize actin in the slime mold, Dictyostelium discoideum. The distribution of actin in migrating cells is different from that in feeding cells. Migrating amebas display fluorescence primarily in advancing regions whereas feeding amebas show uniform ... | 355,262 | [
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A flexural method for evaluation of metal-ceramic bond strengths. | A test technique is presented for evaluating metal-ceramic bond strengths. The test piece consists of a four-point loaded metal beam with porcelain bonded to the central tension side of the beam. The test produced failures at predictable locations and was able to differentiate between metal surface treatments. | 355,275 | [
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Maternal smoking and congenital malformations: an epidemiological study. | In a case-control study undertaken in several hospitals in Connecticut, it was found that women who reported smoking more than 20 cigarettes a day during pregnancy had a relative risk of about 1.6 for congenital malformations in the offspring of that pregnancy compared with women who said they had not smoked at all dur... | 355,285 | [
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Stress management training for the elderly: a psychoeducational approach. | A procedure is described for teaching elderly persons the use of relaxation as a coping skill. The procedure, called Stress Management Training, seeks to provide the client with: 1) a cognitive understanding of stress and relaxation, 2) the ability to relax by controlling muscle tension and sympathetic-nervous-system a... | 355,296 | [
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[A study of two proteins associated with pregnancy. HPL and SPI glycoprotein, in the serum of 692 pregnant women (author's transl)]. | The authors study the evolution of the levels of two proteins found in pregnancy (HPL and SP1 glycoprotein) in the serum of 692 pregnant women. They establish normal and pathological zones. They study particular cases (twins, hydramnios and kidney pathologies). The relationships between fetal distress, maturity, and th... | 355,301 | [
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0.1012793,
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Multiple volar carpometacarpal joint dislocation. Case report of traumatic volar dislocation of the medial four carpometacarpal joint in a child and review of the literature. | Traumatic dislocation of the medial four carpometacarpal joints in a child is an unusual injury. Descriptions of this injury in the literature have been reviewed and a case is presented to illustrate the pertinent anatomy, biomechanical aspects, and details of management. Specifically, the importance of collateral circ... | 355,303 | [
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A model for the autosensitization autoantibody production associated with xenogeneic thymic RNA. | Normal C57BL/6 bone marrow cells cultured for 3 weeks with xenogeneic thymic RNA and syngeneic C57BL/6 antigens (immunoglobulin G or red blood cells) produced anti-immunoglobulin antibody or anti-mouse red blood cell antibody (hemolysin). Addition of both xenogeneic thymic RNA and autoantigens to bone marrow cultures w... | 355,551 | [
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Escherichia coli in bacteremia: K and O antigens and serum sensitivity of strains from adults and neonates. | Comparisons of O- and K-antigenic types and serum sensitivity were carried out with 149 strains of Escherichia coli isolated from adults with bacteremia and 46 strains from neonates with bacteremia. O-antigenic types O6, O4, O2, O16, O18, and O7 were observed most frequently, but their relative prevalence did not diffe... | 355,575 | [
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Effects of progesterone on chemosensitivity in normal men. | Progesterone administration increase VE in man, but its effects on ventilatory response to hypercapnia and hypoxia have not been well documented. Accordingly, VE, HVR, and HCVR were measured during placebo and MPA administration in 11 normal men. The effect of MPA (20 mg orally q 8 hr for 32 hr) on T degrees, metabolic... | 355,585 | [
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Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial. | A controlled, prospective, randomized study evaluated the use of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and/or radiotherapy in the treatment of patients who were operated on and had histological confirmation of anaplastic glioma. A total of 303 patients were randomized into this study, of whom 222 (73%) were withi... | 355,604 | [
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Failure of silastin chin implant four years postoperatively. | Failure of a preformed Silastic chin implant nearly four years after insertion is reported. It is the obligation of all clinicians to report failures as well as successes to provide data for comprehensive evaluation of various techniques and materials. | 355,608 | [
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Correction of the atrophic alveolar ridge by interpositional bone grafting: a progress report. | A retrospective study of postoperative stability and osseous changes was made on nine patients with maxillary or mandibular atrophy who were treated with interpositional bone grafting techniques. There was minimal discernible positional change or resorption of the portion of the maxilla or mandible that was moved by in... | 355,610 | [
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0.043057,
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0.04471823,
0.0946... |
A method of decontamination of ultrasonic scalers and high speed handpieces. | The use of contaminated water in high speed handpieces and ultrasonic handpieces presents potential hazards to both dentist and patient. This study has shown that after waterline sterilization, the use of a sterile, disposable membrane filter can eliminate the microflora from the water of an ultrasonic scaler for up to... | 355,619 | [
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0.0372176... |
Detection of mutagenicity of the colon carcinogen 1,2-dimethylhydrazine by the host-mediated assay and its correlation to carcinogenicity. | Mutagenic potential of 1,2-dimethylhydrazine (DMH) was investigated in the host-mediated assay with mice used as hosts. This assay revealed potent mutagenicity of this colon carcinogen for Salmonella typhimurium G46. The mutagenicity of DMH was inhibited by pretreatment of mice with disulfiram. In addition, mouse strai... | 355,648 | [
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-0.1353552... |
The effect of oral bethanechol chloride on the cystometrogram of the normal male adult. | A double-blind study of the effects of placebo and oral bethanechol chloride (25, 50 and 100 mg.) on the carbon dioxide cystometrogram of the normal male adult was done. Statistical analysis of the data showed no significant dose-response relationship for any of the parameters measured. | 355,661 | [
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[Chromosomal abnormalities in human neoplasia (author's transl)]. | Multiple connections exist between chromosomal aberrations and malignant tumors. It is the aim of the present article to summarize the data known so far in view of i) cancer-prone chromosome abnormalities, ii) chromosome abnormalities related to tumors and iii) chromosome abnormalities related to carcinogens. In some i... | 355,713 | [
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The spread of chloroquine-resistant falciparum malaria in Papua New Guinea. | Two cases of chloroquine-resistant Plasmodium falciparum malaria have been reported from eastern Papua New Guinea in order to alert the medical profession about the spread of resistant strains throughout that territory. | 355,814 | [
-0.09372706,
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-0.061049... |
Restriction enzyme analysis of mitochondrial DNAs of petite mutants of yeast: classification of petites, and deletion mapping of mitochondrial genes. | We have analyzed the restriction digest patterns of the mitochondrial DNA from 41 cytoplasmic petite strains of Saccharomyces cerevisiae, that have been extensively characterized with respect to genetic markers. Each mitochondrial DNA was digested with seven restriction endonucleases (EcoRI, HPaI, HindIII, BamHI, HhaI,... | 355,853 | [
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[X-ray structural analysis of pepsin. V. Conformation of the main chain of the enzyme]. | A detailed description of structural investigations of pepsin from 3.5 to 2.7 A resolution are given. The main attention is drawn to the conformation of the polypeptide backbone of the enzyme. The numbers of amino acid residues involved in the formation of various structural elements are listed. The structure of pepsin... | 355,868 | [
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... |
[Comparison of EMG tracings obtained by means of computer analysis and by routine quantitative method]. | The purpose of the present work was to compare EMG tracings obtained by the automatic method using the computer ANOPS and by the method of quantitative electromyography. The measurements of the automatic method were found to be reliable and reproducible permitting to distinguish normal from pathological tracing, and in... | 355,908 | [
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0.0500088... |
Pituitary gonadotropin response to LHRH in human pregnancy. | The effect of synthetic LHRH on serum levels of FSH, LH, and hCG was determined during early and midgestation. Eight healthy volunteers were studied during the first (8--9 weeks) and second (15--20 weeks) trimesters of pregnancy with 4 patients in each group. Serum samples, obtained before and 15, 30, 45, 90, 120, 150,... | 355,962 | [
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The longevity of Clonorchis sinensis. | The persistence of Clonorchis sinensis infestation of the bile duct for a period of at least 26 years without neoplasia supervening is reported in a Chinese immigrant to Australia. | 355,989 | [
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A micromethod for measuring neutrophil candidacidal activity in neonates. | We developed a micromethod, requiring but a few drops of blood, for measuring the ability of neutrophils to kill ingested Candida albicans. The neutrophils of 10 normal adults killed 26.2 +/- 9.5% of ingested C. albicans in 2.5 hr in a standard fungicidal assay, and 21.4 +/- 6.5% in our new micromodification. Neutrophi... | 355,993 | [
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The stimulus secretion coupling of glucose-induced insulin release. XXVII. Effect of glucose on K+ fluxes in isolated islets. | The effect of glucose upon the handling of K+ by islets of Langerhans removed from normal rats was investigated by measuring both the net uptake of 86Rb+ and its efflux from prelabelled islets. The inflow of K+ into islet cells is mediated, in part at least, by an ouabain-sensitive pump. Glucose fails to affect the inf... | 355,997 | [
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... |
Pretransplant assays of alloimmunity in predicting renal graft outcome. | Forty-one renal allograft recipients were studied for evidence of specific antidonor alloimmunity prior to transplantation. Pretransplant evidence of antibody to the donor as detected by ADCC correlated with the occurrence of early graft loss. This suggests that the ADCC may serve as a useful pretransplant corssmatchin... | 356,029 | [
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0.0418... |
Direct demonstration of duplicate tuf genes in enteric bacteria. | Radioactive tuf mRNA was used to detect the tuf gene in bacterial DNA that had been digested by various restriction endonucleases. Both the K-12 and the B strains of Escherichia coli contain two tuf genes, but no more than two. Salmonella typhimurium also contains duplicate tuf genes. | 356,046 | [
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Visualization of the intracellular development of bacteriophage lambda, with special reference to DNA packaging. | To reveal intermediates in lambda DNA packaging, infected cells were osmotically ruptured and the cell lysates were deposited on electron microscope grids by sedimentation through a sucrose/formalin cushion. A fixation procedure that crosslinks head-related structures to DNA allowed us to study successive stages in the... | 356,048 | [
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Patient compliance: practical implications for physical therapists. A review of the literature. | Patients do not always follow medical advice. This literature review describes the extent to which patients fail to comply, methods of measuring compliance, factors affecting compliance, and programs to obtain maximal compliance. Although most of the literature on patient compliance stems from drug studies, physical th... | 356,066 | [
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Echocardiographic evaluation of pericardial diseases. | This review has attempted to summarize the usefulness of echocardiography in pericardial effusion and other pericardial diseases. As stated before, it is an extremely useful technique for the detection and following of patients with pericardial effusion. The usefulness in other forms of pericardial disease is less well... | 356,121 | [
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The transseptal approach to the pituitary gland. | Transseptal, transsphenoidal pituitary surgery is safe and effective in the management of various problems associated with the region of the sella turcica. This series include 285 operations on 272 patients treated from Sept. 1, 1972, to Sept. 1, 1976. The operative mortality was 1.75%. In every patient, the anatomy sh... | 356,161 | [
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A radioimmunoassay of the pregnancy-specific beta1-glycoprotein (SP1). | A radioimmunological method for determination of the pregnancy specific beta1-glycoprotein (SP1) is described. Antigen specificity of rabbit anti-human SP1 serum (Behringwerke) was investigated against human placental and pituitary hormones. The sensitivity was about 10 microgram/l. The concentration ranges of SP1 in u... | 356,177 | [
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... |
beta-lactamase production by strains of Escherichia coli of intermediate susceptibility to beta-lactam antibiotics. A study of their clinical significance in urinary tract infection. | In a prospective study of patients treated with cephalexin or co-trimoxazole, almost all isolated E. coli strains of intermediate susceptibility to ampicillin or cephalosporin (MIC 2-16 microgram/ml) were shown to produce beta-lactamase detectable with a chromogenic cephalosporin substrate, or by the clover-leaf test o... | 356,181 | [
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0.056... |
Diabetic nephropathy. Experiences through seven years. Survival curves and causes of death. | A 7-year material is presented comprising 38 diabetic nephropathy patients who were treated by dialysis and transplantation. The cumulative patient survival rate after one year is 39%. The survival rate of the transplanted diabetic patient is poorer than that of the transplanted non-diabetic patient. However, no differ... | 356,187 | [
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0.1975767,
0.2889541,
-0.0736481,
0.2390516,
0.2551644,
0.407344,
-0.0294886... |
Kidney transplantation in diabetic nephropathy: four years experience. | Since 1972 65 patients with diabetic nephropathy have been evaluated for renal transplantation. Twenty one were not accepted, 6 died before transplantation and 10 are still under observation. Of 28 transplanted patients 13 are alive with functioning graft, and 3 are treated with hospital dialysis. Patient survival at o... | 356,189 | [
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0.4259929,
0.052644... |
Hyperparathyroidism in uremia and after kidney transplantation. | From 1969 until the end of 1976, 376 patients have had kidney transplants in our department. Fourteen patients have had subtotal parathyroidectomy done, either in their uremic phase or after a successfull kidney transplantation. All patients, except one, who had an adenoma, had varying degrees of hyperplasia of the gla... | 356,194 | [
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... |
Kidney preservation with Collins' and Sachs' solution. | We suggest that the flush-out and short-term-storage solution (Brunius-Gelin) solution so far used in Scandinavia prior to continuous hypothermic perfusion, be replaced by Collins' C2 solution or Sachs' II solution. The question of which one of these should be preferred will need further elucidation. The advantages to ... | 356,213 | [
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0.1959096,
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0.07689254,
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-0... |
A long-term double-blind comparative study on proquazone (Biarison) and ibuprofen in rheumatoid arthritis. | The efficacy and tolerance of proquazone, 900 mg, and ibuprofen, 1200 mg, were compared in a randomized, double-blind clinical trial of 6 months' duration, with 44 patients, 21 on proquazone and 23 on ibuprofen. Comparison of proquazone-treated patients with patients treated with iburofen showed a significantly better ... | 356,239 | [
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0.05166019,
0.03403108,
0.09814933,
-0.133046... |
Diclofenac sodium (Voltaren) and naproxen in the treatment of rheumatoid arthritis: a comparative double-blind study. | In a double-blind, between-patient trial the efficacy and tolerability of two new non-steroid anti-inflammatory analgesics-diclofenac sodium (Voltaren) 50 mg b.i.d. and naproxen 250 mg b.i.d.-were compared in hospitalised patients with rheumatoid arthritis. Both drugs had a clearly positive effect on the duration of mo... | 356,247 | [
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-0... |
Bone marrow origin of hepatic macrophages (Kupffer cells) in humans. | Hepatic macrophages (Kupffer cells) from two male recipients of bone marrow transplants from females were studied for fluorescent Y body staining and sex chromatin (Barr body). After the transplant, macrophages had the sex karyotype of the donor, indicating that human hepatic macrophages originate in bone marrow. | 356,266 | [
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... |
Sir John Harington, Thomas Crapper, and the flush toilet. | With the population explosion of the last century, major changes in sewage removal and sanitation were necessary. Two men offered important designs for the modern flush toilet. Sir John Harington was a poet in 16th Century England, while Thomas Crapper was a plumber and businessman in the same country 300 years later. ... | 356,276 | [
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0... |
Protective effect of propranolol in the treatment of ischemically damaged canine kidneys prior to transplantation. | Warm ischemia is a potential problem during the harvesting of cadaveric kidneys for transplantation purposes. This ischemia can cause impaired renal function following transplantation. The purpose of our study was to determine whether the beta-adrenergic blocking agent propranolol was effective in improving renal funct... | 356,313 | [
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0.2782753,
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[Genetic nature of neoplastic transformation]. | The necessity is substantiated to discriminate between the two notions: the oncogenic potency of cell genome and the conditions which either favour or prevent its realization. Both epigenetic alterations and mutations may cause neoplastic transformation of the cell but the expression of the tumor phenotype, composed of... | 356,361 | [
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0.1652549,
0.5104449,
0.1347953,
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0.... |
Mortality and morbidity in pretransplant bilateral nephrectomy: analysis of 305 cases. | The surgical riks were analyzed in 305 patients with end stage renal failure who underwent bilateral nephrectomy through midabdominal approach in preparation for kidney transplantation. The over-all mortality rate was 3.6 per cent. Age was the most significant risk factor in the mortality. Patients less than fifty year... | 356,390 | [
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0.2550246,
0.3185167,
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... |
Scanning electron microscopy of the small intestine of a normal unsuckled calf and a calf with enteric colibacillosis. | Sections of the small intestine were taken under general anaesthesia from a normal calf and from a calf with enteric colibacillosis and examined by scanning electron and light microscopy. In the normal calf villi were long and oval throughout the intestine and in the challenged calf there was villous stunting and fusio... | 356,408 | [
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0.1039141,
0.1698066,
0.08518328,
... |
The effect of Gn-RH on the pregnancy rate of artificially inseminated cows. | One hundred and nine pure bred Holstein Friesians were injected intramuscularly with 0.125 mg of a synthetic Gn-RH analogue at the time of the first service to study the effect of Gn-RH on the fertility of inseminated cows. Sixty-four cows or 58.7 per cent were diagnosed as pregnant after one insemination compared to 5... | 356,409 | [
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0.2013403,
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0.4312077,
0.3108282,
-0.20... |
[Distribution and characteristics of the R factors in E. coli isolated from poultry]. | It has been demonstrated that Escherichia coli organisms isolated from birds in the district of Haskovo are up to 65 per cent resistant to drugs. It has been experimentally shown that the genetic determinants of resistance to chemotherapeutics are transferred via conjugation. The possibility of transferring R-factors f... | 356,413 | [
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Neurological syndromes produced by some toxic metals encountered industrially or environmentally. | Toxic metals encountered industrially or environmentally may produce the following syndromes: 1) Peripheral neuropathy: which is mainly sensory in arsenic and entirely motor with inorganic lead, organophosphorus compounds and tallium produce a mixed form of peripheral neuropathy. 2) Encephalopathy: usually with lead po... | 356,438 | [
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0.03721029,
... |
C-peptide in juvenile diabetes. | C-peptide can be used as a measure of endogenous insulin secretion in insulin treated diabetics with insulin antibodies. At the onset of juvenile diabetes insulin production is thought to be absent or minimal, but we have found rather high levels of C-peptide, even in ketoacidotic patients. The ketoacidosis does not me... | 356,517 | [
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0.1941794,
0.2765281,
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-0.01787104... |
Prophylactic treatment with miconazole in patients highly predisposed to fungal infection. A placebo-controlled double-blind study. | In a placebo-controlled double-blind study the prophylactic value of oral systemic treatment with the antimycotic agent miconazole was assessed in 30 highly predisposed patients receiving intensive cytostatic chemotherapy because of haematological malignancies. Patients colonized with Candida before treatment were not ... | 356,523 | [
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0.1146805,
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0.2... |
Animal models: importance in research on hemorrhage and thrombosis. | Despite some sentiments against animal research, animal models continue to be important in studying hemorrhage and thrombosis. Examples of genetic models are dogs and pigs with von Willebrand's disease. The homozygous von Willebrand pig appears to be resistant to arteriosclerosis, presumably due to impairment of the pl... | 356,556 | [
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0.0689267,
-0.292728... |
A comparison of two indirect methods for localizing the site of urinary infection: beta glucuronidase levels and the presence of antibody-coated bacteria. | A comparison of two of the indirect methods used for localization of the site of urinary tract infection was made for 218 obstetric patients. There was no correlation between urinary beta glucuronidase activity and the presence of a positive fluorescent antibody test. The ranges of beta glucuronidase activity were so v... | 356,602 | [
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0.3951882,
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0.02513488,
0.3... |
Immunocytochemical diagnosis of alpha-1-antitrypsin deficiency. | Eight cases of liver disease associated with alpha-1-antitrypsin deficiency are described. Six of the cases, including the only childhood case, showed no evidence of lung disease. An occult but variable clinical course is defined in this disorder. A spectrum in the severity of tissue change was noted, and in some insta... | 356,632 | [
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... |
Effects of acute alcohol administration on reproductive endocrinology in the male rat. | The results of the current studies further document that acute alcohol administration markedly disrupts the function of the HPG in the male. Our results indicate that alcohol depresses serum testosterone levels and, thereby, produces clinical symptoms associated with hypoandrogenization. Moreover, our studies suggest t... | 356,645 | [
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Effects of alcohol on plasma testosterone and luteinizing hormone levels. | The findings obtained in this study indicate that the major effect of ethanol on plasma testosterone levels is occurring at a peripheral (testicular) rather than central (hypothalamic-pituitary) site. | 356,646 | [
0.01655729,
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Ethanol increases rate of isolated atria. | Ethanol has a positive chronotropic and negative inotropic effect on isolated spontaneously beating rabbit atria. Both effects increased with increasing ethanol concentrations in the bathing medium. This response is apparently a direct action of ethanol on the myocardium and is not due to the release of catecholamines,... | 356,648 | [
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0.1793566,
0.04533087,
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Effect of an acute dose of ethanol on rat liver microsomal mixed function oxygenase components and membrane lipid composition. | The lipid composition of rat liver microsomes was not altered in response to a single acute dose of ethanol relative to isocaloric glycerol-treated controls. Microsomal cytochrome P-450 was transiently elevated, the elevation paralleling blood ethanol levels. Microsomal NADPH oxidase was transiently elevated relative t... | 356,656 | [
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0.03234667,... |
Antihypertensive drug combinations: prazosin, hydrochlorothiazide and clonidine. | Fourty-six men and 6 women aged 45 years and having arterial hypertension newly diagnosed at routine medical examinations were given out-patient antihypertensive treatment with prazosin, prazosin + hydrochlorothiazide, or prazosin + hydrochlorothiazide + clonidine. The mean values of blood pressure after the 3-week pla... | 356,719 | [
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0.1398626,
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... |
Bactericidal activity of cephalosporins in an in vitro model simulating serum levels. | The bactericidal activity of cefazolin, cephaloridine, and cephalothin in a simulated intramuscular study (500 mg) and a simulated intravenous drip infusion study (2 g/2 h) is reported. In both model systems, the bactericidal activity of cefazolin surpassed that of cephalothin, and there were certain differences betwee... | 356,725 | [
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0.2673908,
0.342328,
0.06947514,
0.3797656,
-0.... |
[Morphological and structural variations of the human inguinal region (author's transl)]. | In the inguinal region, numerous muscular and fibrous alterations are described. They are related to the unconstant position of the pubic tubercle in relation io the interspinous diameter (linea bi-spinalis). The pubic tubercle can be observed in two different locations: either high or low. The high location is charact... | 356,729 | [
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0.09976312,
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... |
Development of pineal complex in Calotes versicolor. | The general plan of the development of the organ in Calotes versicolor in no way differs from that of Sphenodon and Lacerta. The lens of the parietal eye of Calotes appears at a comparatively later state of development than in Sphenodon and Lacerta. The papaphysis in the embryos of Calotes versicolor is a simple struct... | 356,730 | [
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0.1259644,
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[Action of DDT on colonization of the chick embryonic genital ridges, by primordial germ cells (author's transl)]. | Colonization of the genital ridges by primordial germ cells was quantitatively studied, at stages 18-24, in Chick embryos issued from eggs treated with commercial DDT before incubation. The pesticide provokes, dating from the 4th day of development (stage 24), a significant reduction in the gonadal germ population. Thi... | 356,732 | [
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0.2293871,
0.2803875,
0.3512173,
0.3792509,
0.1323613,
-0.09286748,
... |
[Request for sampling and acquisition of biological samples for microbiological investigation (author's transl)]. | On the grounds of published data and of those resulting from an investigation carried out in the Italian hospitals, the writers propose to standardize the requests for microbiological exams and the sampling procedures and the acquisition of the materials to be subjected to bacteriological examination. | 356,766 | [
-0.1182413,
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0.08979283,
0.09992027,
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0.2476817,
0.3219737,
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... |
[Evaluation of survival of bacteria on dry swabs and transport systems (author's transl)]. | The survival of bacteria on dry swabs varied from twenty pro cent of organisms alive to no viability at four hours after the inoculation. Cotton-wool swabs highly reduced survival of bacteria; alginate or albumin swabs were less toxic for Gram-positive bacteria, charcoal swabs for Gram-negative bacteria. Transport syst... | 356,768 | [
0.0363823,
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0.1261377,
0.08609869,
0.2181942,
0.3978328,
0.3431509,
-0.1228158,
0... |
[Neutrophil function in children with acute lyphoblastic leukemia]. | Neutrophil function has been studied in 12 patients with acute lymphoblastic leukemia by means of the NBT test and bactericidal assay against E. coli. Tests have been performed before and during treatment. In untreated patients the bactericidal activity of neutrophils was normal, in spite of the decreased number of cel... | 356,784 | [
0.1115879,
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0.09157273,
... |
[A system of automatic image processing and possibilities of its usage (author's transl)]. | Prior to the description of the hardware and the developmental possibilities of the hardware, general principles of image processing systems are explanated and the properties for the utilizing of this measuring method are outlined and delimites. Actual problems, being worked at, and hitherto existing results are report... | 356,800 | [
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0.3070094,
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0.0689208,
0.4825467,
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The characteristics of a new glucose sensor for use in an artificial pancreatic beta cell. | A new glucose sensor has been developed for the continuous extracorporeal monitoring of blood glucose concentrations in conjunction with an artificial pancreatic beta cell simulator. This sensor has a rapid ninety percent response time (less than 1 min), is stable for periods of up to 140 hours of accumulated use and c... | 356,828 | [
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0.2211408,
0.102447,
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0.1446237,
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0.02783686,
0.2630971,
0.1180729,
0.2237805,
... |
Factors in the spread of salmonellas in meatworks with special reference to contamination of knives. | Immersion of knives momentarily in hot water (82 degrees C) was ineffective in destroying salmonellas on knives used in a meatworks to carry out the bung dropping operation. Laboratory experiments confirmed that knives covered with meat products required 10 or more seconds to be effectively decontaminated at this tempe... | 356,840 | [
0.0341077,
0.05602264,
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0.04898518,
0.1584718,
0.306297,
0.3433665,
-0.004455345,... |
Comparative trial of atenolol and propranolol in hyperthyroidism. | 1 The use of atenolol, a cardioselective beta-adrenoceptor antagonist, in the management of hyperthyroidism has been studied by comparing it with propranolol. 2 In a double-blind cross-over trial, atenolol (50 mg), propranolol (40 mg) and placebo 4 times daily for 1 week were compared in twenty-one hyperthyroid patient... | 356,867 | [
-0.007866499,
0.03910096,
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0.06768505,
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0.016429,
-0.04802236,
0.08317761,
-0.08064243,
0.2359043,
-0.123401... |
Purification and properties of trehalase from the thermophilic fungus Humicola lanuginosa. | Trehalase (alpha,alpha-Trehalose glucohydrolase, EC 3.2.1.28) was partially solubilized from the thermophilic fungus Humicola lanuginosa RM-B, and purified 184-fold. The purified enzyme was optimally active at 50 degrees C in acetate buffer at pH 5.5. It was highly specific for alpha,alpha-trehalose and had an apparent... | 356,886 | [
0.05329818,
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0.0835349,
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0.1122994,
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-0.127616,
0.2413673,
0.09211238,
0.4450808,
0.2619517,
-0.2732187,... |
Ultrastructural localization of beta-D-galactan in the nuclei of the myxomycete Physarum polycephalum. | The acellular slime mold Physarum polycephalum produces an extracellular sulfated and phosphorylated beta-D-galactan which was recently isolated from the nuclei of this organism. This polysaccharide has now been localized in the nuclei of P. polycephalum by electron microscopy using a specific "sandwich" technique: thi... | 356,891 | [
0.1028401,
-0.1790553,
0.1758566,
0.2475083,
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0.2334094,
0.02850664,
0.5794634,
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0.104135,
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0.1211943,
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0.2489082,
-0.226159,
0.7483436,
0.3055386,
0.0337579,
-0.1... |
Biphasic saturations of binding proteins can be the result of a competitive inhibition of substrate fixation. | A mathematical model is proposed which explains some biphasic saturations of Binding Proteins by their substrates through an effect of a competitive inhibition. The inhibitor can be the substrate itself especially when the retention phenomenon is occuring. This model has been verified with two periplasmic Binding Prote... | 356,896 | [
0.03443304,
0.03232741,
-0.072675,
0.03461985,
0.1785975,
-0.3121573,
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0.1208962,
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0.2073499,
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0.1955366,
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-0.5919489,
-0.08825925,
-0.1877631,
0.08960831,
0.07598305,
0.2077716,
0.05151885,... |
A contrast variation study of Escherichia coli ribosomes reassembled from protonated and deuterated subunits. | Neutron low angle scattering studies on E. coli ribosomes reassembled from protonated and deuterated subunits indicate that the association of the two subunits occurs without major distortion of their shape or modification of the distribution of the protein and RNA components. | 356,907 | [
-0.08250021,
0.1830605,
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0.08029387,
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0.3041059,
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-0.0... |
[Common antigens of stable group A streptococcal L forms and muscle fibers of human myocardium]. | The immunofluorescence method was used to demonstrate that the antigens of stable streptococcus L-forms and of the cytoplasmic membrane of human myocardium muscle fibers were common. The common antigen was included into the composition of the surface membrane of the muscle cell adjacent to the sarcolemma, and of the tr... | 356,911 | [
0.08333606,
0.08523676,
0.160607,
0.04822705,
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0.1991019,
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0.1428393,
0.7220799,
0.04354721,
-0.2631938,
0.0... |
Clinical trial of rubidazone in solid tumors and malignant lymphomas. | Rubidazone, a semisynthetic daunorubicin derivative, was administered to 33 patients with advanced solid tumors or malignant lymphomas. The doses used were 200, 150, or 100 mg/m2 repeated at 3-week intervals. The antitumor effect was very modest. Partial remission was obtained in only one patient and stable disease was... | 356,967 | [
-0.2322342,
-0.2748841,
0.0186098,
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0.1886453,
-0.1851787,
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0.009392264,
0.05503359,
0.1483597,
0.3501129,
0.31629,
0.005794891,
0.1332657,
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-0.7131738,
0.1193733,
-0.134889,
0.22883,
0.350884,
0.2865318,
0.02205276,
0.1457... |
Ultrastructure of rat pituitary LH gonadotrophs in relation to serum and pituitary LH levels following repeated LH-RH stimulation. | The effects of single and repeated LH-RH injections at 120 min intervals on female rat LH gonadotrophs and on pituitary and serum LH levels were investigated using electronmicroscopy and radioimmunoassay. A temporary stimulation of granule release, of protein and new granule synthesis and of the accumulation of lysosom... | 356,999 | [
0.1519974,
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0.3420579,
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0.0688016,
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0.3219755,
0.08843496,
0.06625213,
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0.05788756,
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0.2241152,
-0.03259146,
0.3082471,
0.4252724,
0.0356254... |
Steady-state kinetics of valproic acid in epileptic patients. | Pharmacokinetic evaluation and prediction were carried out in 20 epileptic patients. Using conventional pharmacokinetic techniques and a one-compartment model, predicted and observed valproic acid plasma concentrations were compared. Valproic acid assay was performed by gas-liquid chromatography. There was good agreeme... | 357,068 | [
-0.1359663,
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0.39624,
0.03792304,
0.0584763,
0.1618865,
0.2740457,
-0.05762321,
... |
Children of depressed and schizophrenic mothers. | A sample of psychotic mothers and their children who were five years or younger when first recruited for our study of high risk children was followed up five years later. The current sample, obtained from our previous work, consisted of 18 schizophrenic, 12 depressed and psychotic, and 22 well mothers and their six to ... | 357,099 | [
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0.2622862,
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0.2221043,
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0.1950095,
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0.03345278,
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-0.363367,
0.4741641,
-0.2770175,
0.1257959,
0.2938724,
0.2967046,
-0.02963456,... |
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