title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Cation transport in Escherichia coli. IX. Regulation of K transport. | Kinetics of K exchange in the steady state and of net K uptake after osmotic upshock are reported for the four K transport systems of Escherichia coli: Kdp, TrkA, TrkD, and TrkF. Energy requirements for K exchange are reported for the Kdp and TrkA systems. For each system, kinetics of these two modes of K transport di... | 359,759 | [
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A new metal-ceramic crown. | A new method of attaching porcelain to precious metals using tin oxide coatings is described. Platinum foil is bonded to aluminous porcelain and forms an inner protective skin, thereby reducing the formation of microcracks and increasing the strength of the crown. An improvement in translucency of the crown is obtained... | 359,783 | [
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A technique for restoring abutments for removable partial dentures. | A technique was presented to restore a removable partial denture abutment so that the removable denture can continue to be used. The technique uses cold-curing acrylic resin in a rubber base impression form. The technique can be adapted to both direct and indirect procedures. | 359,790 | [
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[Role of computer technology and mathematical modelling in the treatment of patients after operations on the heart]. | On the basis of ten-year experience in theoretical studies and experimental tests mathematical models of hemodynamics were built for the follow-up of parameters of the cardiovascular system which cannot be determined by means of any other modern methods. Three years of clinical studies of the Hewlett-Pachard monitoring... | 359,892 | [
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Properties of human malignant glioma cells in vitro. | The properties of human glia and glioma cells in culture are reviewed. Glia-like cells from non-neoplastic brain show all accepted hallmarks of normalcy: limited life span, low terminal cell density, strong density dependent inhibition of proliferation, diploidy and contact inhibition of membrane mobility. Twenty five ... | 359,950 | [
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[Comparative study of the physiological and biochemical characteristics of the varying ploidy of Saccharomyces cerevisiae strains in the process of their growth]. | The growth of Saccharomyces cerevisiae strains having different ploidy was compared in the conditions of periodic cultivation, and was found to consist of two stages: (1) at the account of glucose utilization and (2) due to assimilation of cellular metabolites following a period of adaptation. The secondary growth was ... | 360,014 | [
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Atrial electrogram monitoring in a cardiac care unit. | Routine monitoring of a bipolar atrial electrogram (AEG) simultaneously with the electrocardiogram is a useful and safe clinical technique for the diagnosis of complex cardiac dysrhythmias. The large-amplitude A waves of the AEG can be more reliably identified than the corresponding low-amplitude p waves of the electro... | 360,019 | [
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Analysis of the regulatory mechanisms controlling the synthesis of the hexitol transport systems in Escherichia coli K12. | The synthesis of the transport systems (enzymeII-complexes) coded for in the mtl and in the gut (srl) operon was found to be induced by unphosphorylated D-mannitol and D-glucitol respectively. Induction from the outside however is only possible if these polyols are taken up into the cells. Induction of the D-mannitol s... | 360,044 | [
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Basis for slow growth on the non-fermentable substrates by a Saccharomyces cerevisiae mutant UV-sensitive for rho- production. | The mutant uvsrho 72 of Saccharomyces cerevisiae UV-sensitive for rho- production displays slower growth on media containing non-fermentable carbon sources such as glycerol or lactate. The slower growth on glycerol is not due to any deficiency in glycerol catabolism or mitochondrial oxidative phosphorylation. No modifi... | 360,046 | [
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H2B nucleohistone-phospholipid interactions. Thermal denaturation and ultrastructural analysis. | Sphingomyelin, phosphatidylserine, bovine lecithin and phosphatidylethanolamine modify the thermal stabilization of H2B-DNA complexes, by inducing stabilization at 0.3 and 0.6 H2B : DNA weight ratios and destabilify the arrangement of nucleohistone is confirmed by ultrastructural analysis which indicates a competitive ... | 360,047 | [
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An evaluation of cytogenetic analysis as a primary tool in the assessment of recurrent pregnancy wastage. | Cytogenetic evaluation of couples with recurrent pregnancy wastage is frequently performed only after other possible etiologic factors have been excluded. Previous reports of studies using conventional and G-banding chromosome techniques in these couples have shown a higher frequency of translocations than that found i... | 360,121 | [
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3'End labelling of RNA with 32P suitable for rapid gel sequencing. | A new general method of labelling the 2',3'-diol end of RNA with 32P has been devised suitable for gel sequencing. Poly(A) polymerase (E. coli) is incubated with the RNA and limiting amounts of alpha-32P-ATP. The mono-addition product is then cleaved with periodate and beta-eliminated with aniline, leaving the RNA term... | 360,168 | [
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Physiochemical studies on interactions between DNA and RNA polymerase. Ultraviolet absorption measurements. | The interaction between Escherichia coli RNA polymerase and a restriction fragment of coliphage T7 DNA containing four promoter sites for the coli enzyme has been studied by difference uv absorption spectroscopy in a low ionic strength buffer containing 10 mm MgCl2 and 50 mM KCl. The binding of the enzyme to the DNA is... | 360,169 | [
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A photoaffinity labelling study of the messenger RNA-binding region of Escherichia coli ribosomes. | A photoaffinity labelling study of the messenger RNA-binding region of E. coli ribosomes has been made, using oligoadenylic acids as mRNA analogs. The oligonucleotides, of chain length 6 to 8 and thus several nucleotides longer than oligonucleotides previously employed for this purpose, carried a radioactive photolabil... | 360,171 | [
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[LH-RH content in different parts of the hypothalamus and blood of rats with an altered level of thyroid hormones]. | Luliberin (LH-RH) in the preioptic region of the hypothalamus, the region of the arcuate nuclei, and of the medial eminence, the region of the dorsomedial nuclei and in the blood serum was studied in intact female rats with a stable 4-day cycle, and also in thyroidectomized female animals. LH-RH content rose significan... | 360,203 | [
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Isolation and characterization of colonic tissue-bound antibodies from patients with idiopathic ulcerative colitis. | To determine if specific anticolon antibodies bound to colonic mucosa occur in ulcerative colitis, we obtained surgical specimens of colon from five patients with ulcerative colitis, one patient with diverticulitis, and three control subjects with carcinoma. Two specimens of ileum and cecum were also obtained from pati... | 360,223 | [
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Three double-blind comparative trials of mianserine (ORG GB 94) and amitriptyline in the treatment of depressive illness. | The results of double-blind comparative trials carried out simultaneously in three Finnish hospitals are presented. The antidepressant activity and side-effects of mianserine (ORG GB 94) and amitriptyline were compared. No statistically significant differences were found between the two treatments. It was found, howeve... | 360,231 | [
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[Interaction between antihypertensive agents and psychotropic drugs (author's transl)]. | The present review paper is dealing with the interaction between antihypertensive agents and various psychotropic drugs. Various psychotropic drugs enhance certain-side-effects of the antihypertensive substances, like sedation, extrapyramidal disorders and orthostatic hypotension. On the other hand, the blood-pressure ... | 360,243 | [
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Prediction of response to chlordiazepoxide and placebo in anxious outpatients: an attempt at replication. | The present study seeks to determine the extent to which a set of non-specific factors can stably predict response to either chlordiazepoxide (CDZ) or placebo (PBO) and the extent to which such prediction is specific to or distinctive for each treatment agent. For this purpose data were assembled for 447 primarily anxi... | 360,247 | [
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Rapid germination of Aspergillus fumigatus conidia in mouse kidneys and a kidney extract. | Intravenously injected conidia of Aspergillus fumigatus germinated rapidly in the kidneys of untreated and cortisone-treated specific-pathogen-free (SPF) mice and in the livers of cortisone-treated SPF mice. Extracts of kidneys from untreated and cortisone-treated mice stimulated germination of A. fumigatus conidia in ... | 360,442 | [
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Preliminary investigation of the use of the enzyme linked immunosorbent assay (ELISA) in the serodiagnosis of mycetoma. | Antibody levels in a small group of Sudanese patients with clinically diagnosed mycetoma, and control groups were measured by countercurrent immunoelectrophoresis (CIE) and enzyme linked immunosorbent assay (ELISA). Antigens were prepared from the following organisms: Streptomyces somaliensis, Actinomadura madurae, A. ... | 360,443 | [
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Enzyme immunoassay for cortisol in serum using cortisol 21-amine. | Cortisol 21-amine (21-amino-11beta,17-dihydroxy-4-pregnene-3,20-dione) was prepared and an enzyme immunoassay for cortisol in serum was established using cortisol 21-amine conjugated with alkaline phosphatase. The minimal amount of cortisol detected was 1ng/tube and the measurable range was from 1 to 80 microgram/d1, u... | 360,490 | [
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Evaluation of urodynamic studies by computer. | In an attempt to simplify urodynamic evaluation, the data obtained from cystometry, urethral profile and flowmetry were analysed using the ICS recommendations for standardization and terminology. All studies were compiled from check lists feasible for computation. The aim was to establish standards and "typical" change... | 360,555 | [
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[In vitro lysis of schizophrenic patients' erythrocytes in an autologous system]. | Using the Erne method in N.N. Klemparskaya's modification the author studied peripheral blood of 59 schizophrenic patients with different types of the course and 23 normals. It is shown that in the peripheral blood preparations of schizophrenic patients there is a reliably greater number of zones of local hemolysis of ... | 360,728 | [
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Experimental heterotopic pancreas segment transplantation. | Autologous and allogenic transplantations of the caudal part of the pancreas into the omentum and the spleen were performed in 18 dogs. The fate of the transplants was followed histologically. In the grafts the Langerhans-islands preserved their integrity longer than in the other parts of the organ, but in 4 to 6 weeks... | 360,740 | [
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Plaque-inhibiting effect of dentifrices containing stannous fluoride. | The present study showed that the plaque inhibiting effect of aqueous solutions of stannous fluoride can be maintained in toothpastes. A commercial toothpaste containing 0.4 per cent of water soluble tin was effective whereas one containing 0.03 per cent showed no effect. The plaque inhibiting effect was shown in one s... | 360,762 | [
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Comparative investigation between thiethylperazine and meclizine in vertigo of different genesis. | Forty patients suffering from vertigo of different genesis received thiethylperazine 6.5 mg or meclizine 25 mg, 2 capsules a day for 5 days, according to double-blind, cross-over methodology in randomized order. It appeared that the effect on the symptoms vertigo, gait disturbance and nausea does not differ significant... | 360,766 | [
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Centenary of the first correct antemortem diagnosis of coronary thrombosis by Adam Hammer (1818--1878): English translation of the original report. | William Heberden (1710--1801), in 1768, described angina pectoris, the classic symptom of ischemic heart disease, 150 years after the discovery of the coronary circulation by William Harvey (1578-1657). Another 110 years had elapsed before the first antemortem diagnosis (confirmed at autopsy) of coronary thrombosis was... | 360,811 | [
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0.2058444,
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0.3455687,
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0.38511... |
Pyridoxine inhibition of a symbiotic streptococcus. | A symbiotic, alpha-hemolytic streptococcus that showed satellitism about a Staphylococcus aureus was recovered from blood cultures of a patient with endocarditis. Previously reported as being required for growth of symbiotic streptococci, pyridoxine hydrochloride was found to inhibit the growth of this organism. | 360,828 | [
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Evidence for a prostaglandin-independent defect in chloride reabsorption in the loop of Henle as a proximal cause of Bartter's syncrome. | Maximal free-water clearance was measured in five patients with Bartter's syndrome and in five patients with the hypokalemic alkalosis of persistent psychogenic vomiting. Hypokalemic alkalosis, hyperreninemia, hyperaldosteronism and excessive renal production of prostaglandin E2 were present in the patients with both d... | 360,836 | [
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Stapling technic for esophagogastrostomy after esophagogastric resection. | A technic of esophagogastrostomy is described for constructing an end-to-side, back-to-front anastomosis using stapling devices. Twelve consecutive cases are reported with no deaths and no anastomotic leaks. | 360,850 | [
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... |
"Paratransplant" hernia. Three patients with a new variant of internal hernia. | Three cases of bowel obstruction due to internal hernia caused by entrapment of bowel or omentum through a defect in the peritoneum covering the transplanted kidney are described. All three patients survived due to early surgical intervention and reduction of the hernia and/or resection of necrotic bowel or omentum. In... | 360,862 | [
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Evaluation of drug treatment in mild hypertension: VA-NHLBI feasibility trial. Plan and preliminary results of a two-year feasibility trial for a multicenter intervention study to evaluate the benefits versus the disadvantages of treating mild hypertension. Prepared for the Veterans Administration-National Heart, Lung,... | A feasibility trial to investigate the practicality of determining the advantages and disadvantages of prompt pharmacologic treatment for mild hypertension was jointly funded by the Veterans Administration and the National Heart, Lung and Blood Institute. Its clinical phase has been completed, and it demonstrated 1. th... | 360,921 | [
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[Ultra-flash sterilization of fluid food by friction]. | The ATAD process without heat exchange nor steam mixing allows the sterilization in a very short time. With milk, the sterility has been attained regularly at 140 degrees C/0,54 seconds. Only small changes occurred in nitrogen distribution. An homogeneizing effect upon fat emulsion is noticeable. The amino-acid composi... | 360,952 | [
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0.04011255,
0.4142042,
0.1429579,
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A clinical evaluation of benzydamine hydrochloride. | A double-blind clinical trial of the effects of the use of benzydamine hydrochloride for patients undergoing the surgical removal of impacted lower third molar teeth showed no significant effects on swelling and trismus between control and experimental groups, although a significant reduction in the post-operative cons... | 361,026 | [
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0.1024647,
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0.4917166,
0... |
The temporomandibular joint: some biological considerations. | The physiological mechanisms operating through the temporomandibular joint in the perception of changes in the position of the mandible can determine extremely small discrepancies in the final occlusal position. Some observations on the pathways of neural control and reflexes are discussed and their importance in clini... | 361,031 | [
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0.02143851,
0.110491... |
Plasma cortisol values after topical application of diflucortolone valerate (0.3%) or clobetasol propionate (0.05%) in psoriatic patients. | A double-blind randomized study to compare the plasma cortisol values at both 9.00 a.m. and 12 midnight following topical application fo 10 g daily for 7 days of either diflucortolone valerate 0.3% (Nerisone Forte) ointment or clobetasol propionate 0.05% (Dermovate) ointment in 20 hospital inpatients suffering from sev... | 361,060 | [
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0.7286786,
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0.152849,
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The adverse effect of iron repletion on the course of certain infections. | The incidence of infections was studied in 137 iron-deficient Somali nomads, 67 of whom were treated with placebo and 71 with iron. Seven episodes of infection occurred in the placebo group and 36 in the group treated with iron; these 36 episodes included activation of pre-existing malaria, brucellosis, and tuberculosi... | 361,162 | [
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0.348181,
0.0630427,
... |
Influence of genital herpes on results of fluorescent treponemal antibody absorption test. | Both the fluorescent treponemal antibody absorption (FTS-ABS) test and Venereal Disease Laboratory (VDRL) test for syphilis were performed routinely on 113 men with histories of genital ulcerations. The difference in negative VDRL and borderline FTS-ABS results between patients with and without herpes simplex virus in ... | 361,167 | [
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Combination chemotherapy of diffuse histiocytic lymphoma with cyclophosphamide, adriamycin, vincristine and prednisone (CHOP). | Twenty-three patients with diffuse histiocytic lymphoma who had not had prior chemotherapy were treated with CHOP (cyclophosphamide, adriamycin, vincristine, and prednisone). Sixteen of these patients had previously been treated with radiation therapy. Nine of these 23 patients had a pathologically documented complete ... | 361,209 | [
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Ultrastructure of cerebellar hemangioblastoma. | Light and ultrastructural features of a cerebellar hemangioblastoma in a 56-year-old man are described in detail. The neoplasm was composed of three major cell types: endothelial cells, pericytes, and stromal cells. The endothelial cells lined the fenestrated vascular channels. The pericytes were ensheathed by their ow... | 361,212 | [
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Squamous cell carcinoma of the cecum: a case report. | Squamous cell carcinoma of the colon is a distinctly rare entity. Squamous cell carcinoma and adenoacanthoma occur in the colon and upper rectum 0.05% as frequently as adenocarcinoma. Squamous cell carcinoma of the cecum is an even rarer entity, this case appearing to be the seventh recorded case. A review of the liter... | 361,214 | [
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0... |
Primary hyperparathyroidism and chronic lymphocytic leukemia. | Although hypercalcemia is a frequent event during the course of many malignancies it has only rarely been described with patients with chronic lymphocytic leukemia. Review of the literature revealed only eleven such case reports. The mechanism of the hypercalcemia in these patients was generally unclear although one pa... | 361,217 | [
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Demonstration of the display of components of the endoplasmic reticulum system by indirect immunofluorescence microscopy using antibodies against cytochrome b(5) from rat liver microsomes. | Antibodies against the purified fragment of cytochrome b(5) released by trypsin treatment from rat liver microsomes were raised in rabbits and used for the demonstration of membranes rich in cytochrome b(5), in particular the endoplasmic reticulum (ER) system, by indirect immunofluorescence microscopy. The method allow... | 361,257 | [
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Induction of canine autoantibody to prostatic neoantigen. | Electrodesiccation surgery of the prostate glands was completed on a total of seventy-one dogs. Disc electrophoresis, thin layer gel electrofocus and agar double diffusion studies demonstrated unique changes in the extracts of convalescent prostatic tissue that had persisted for at least 6 months when compared with pre... | 361,315 | [
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Effects of oxprenolol and propranolol on systolic time intervals. | Twenty patients with coronary heart disease participated in a double-blind, randomized, crossover study on three study mornings to evaluate the effect of oral oxprenolol 80 mg, oral propranolol 80 mg, and placebo on left ventricular contractility. Systolic time intervals were performed in the control period and at 60, ... | 361,333 | [
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Vitamin D and the syndromes of azotaemic osteodystrophy. | Intestinal malabsorption of calcium and the development of osteomalacia in conservatively treated renal failure is explained by a quantitative deficiency of 1,25-dihydroxycholecalciferol, which also contributes to the development of hypocalcaemia. Excess of 25-hydroxycholecalciferol can substitute for this deficiency. ... | 361,340 | [
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[Interrelationships between the enzymatic functions of the pancreas and small intestine during adaptive processes]. | In rats fed for 4, 15, and 30 days with increased amount of proteins, lipids, and carbohydrates, considerable shifts occurred in activity of enzymes of the pancreas (amylase, protease, and lipase) and small intestine (gamma--amylase, maltase group, invertase, peptidhydrolase, monoglyceriflipase). Mathematical analysis ... | 361,444 | [
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... |
Management of lost finger tips in children. | A trial was run in the Hand Unit of the Royal Victoria Infirmary, Newcastle upon Tyne, involving sixty consecutive children who has sustained finger tip injuries with tissue loss over a period of three years. The three forms of treatment used in different groups of children were split skin grafting, local flap repair, ... | 361,515 | [
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0.04316711,
0.07207724,
0.2898587,
-0.0188682... |
Association of elevated levels of extracellular neuraminidase with clinical isolates of type III group B streptococci. | The level of total extracellular neuraminidase produced by 74 clinical isolates of group B streptococci isolated from diseased or asymptomatically colonized infants was assayed. Extracellular neuraminidase was obtained from concentrated filtrates of exponentially growing cultures of group B streptococci grown in a chem... | 361,576 | [
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0.03539215,
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0.04944399,
0.3360267,
0.3452947,
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... |
Distribution of fenfluramine in normal and obese mice. | Concentrations of fenfluramine and its metabolite, norfenfluramine, were measured in blood, brain and parametrial adipose tissues 15, 30, 60 and 120 min after intraperitoneal (i.p.) administration of fenfluramine hydrochloride (10 mg/kg) to normal and gold-thioglucose obese mice. Concentrations of fenfluramine were hig... | 361,587 | [
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0.4060669,
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... |
[Mediastinoscopy or thoracotomy? A prospective randomized study]. | A prospective, controlled, randomized trial on the value of mediastinoscopy was performed during a 12-month period (1969-1970) on 130 patients with a bronchogenic carcinoma. Patients to be admitted to the study had to meet the criteria of being clinically operable. 126 patients could be followed up for the following 5 ... | 361,645 | [
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0.1340702,
0.6309779,
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0.04048347,
0.17... |
[Surgical and apparative treatment of patients with meningomyelocele with special reference to their hip problems]. | Children with thoracic lesions should have hip surgery done only if this is necessary for the child to be able to walk with braces. In lumbar lesions hip surgery and especially SHARRARD'S procedure of iliopsoas transfer is done to establish muscular balance. The amount of braces for walking can thus be reduced. In sacr... | 361,648 | [
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0.2467287,
-0.3006853,
0.08527119... |
Control of vacuole permeability and protein degradation by the cell cycle arrest signal in Saccharomyces cerevisiae. | Saccharomyces cerevisiae responds to deperivation of nutrients by arresting cell division at the unbudded G1 stage. Cells situated outside of G1 at the time of deperivation complete the cell cycle before arresting. This prompted an investigation of the source of nutrients used by these cells to complete division and th... | 361,691 | [
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0.100622,
0.5680413,
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6-cyanopurine, a color indicator useful for isolating mutations in the nif (nitrogen fixation) genes of Klebsiella pneumoniae. | 6-Cyanopurine (6-CP) can be used as a color indicator for certain classes of nif (N2 fixation) mutations in Klebsiella pneumoniae. Under N2-fixing conditions, Nif+ colonies and most Nif- colonies are purple on media containing 6-CP. Twenty-two Nif- mutants with altered color on medium containing 6-CP were isolated. All... | 361,692 | [
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0.... |
Fine-structure mapping and complementation analysis of nif (nitrogen fixation) genes in Klebsiella pneumoniae. | Four hundred and eighty-nine independent Nif- strains containing 260 point, 130 millimicron-induced, and 99 deletion mutations in nif in the Klebsiella pneumoniae chromosome were isolated. Three hundred and ninety insertion and point mutations were mapped with millimicron-induced deletions carried on 44 plasmids derive... | 361,693 | [
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Cloned DNA fragment specifying major outer membrane protein a in Escherichia coli K-12. | Plasmid pMC44 is a recombinant plasmid that contains a 2-megadalton EcoRI fragment of Escherichia coli K-12 DNA joined to the cloning vehicle, pSC101. The polypeptides specified by plasmid pMC44 were identified and compared with those specified by pSC101 to determine those that are unique to pMC44. Three polypeptides s... | 361,698 | [
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Interactions between uv radiation of different energies in the inactivation of bacteria. | A strong lethal interaction was observed between various monochromatic wavelengths (254, 334, 365, and 405 nm) in the repair-proficient E. coli K-12 strain AB 1157, except in the case of preexposure to 405-nm radiation which resulted in a protection against the inactivation resulting from subsequent exposure to 365-or ... | 361,702 | [
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Analysis of sequences transposed by complementation of two classes of transposition-deficient mutants of Tn3. | The Tn1 and Tn3 elements are closely related transposons which carry the structural gene for ampicillin resistance. Two classes of deletion mutants of the plasmid pMB8::Tn3 (RSF1050) are unable to transpose ampicillin resistance but can be complemented in trans by a coresident Tn1 or Tn3 element. The analysis of the se... | 361,721 | [
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Specific inhibition of in vitro Candida-induced lymphocyte proliferation by polysaccharidic antigens present in the serum of patients with chronic mucocutaneous candidiasis. | A specific inhibitory activity of in vitro proliferative responses of normal human lymphocytes to Candida metabolic antigen was found in the serum of 6 out of 23 children with chronic mucocutaneous candidiasis. In each of the six patients, the presence of an inhibitory activity was associated with Candida-specific cell... | 361,754 | [
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Distribution of enterobacteriaceae in recycled manure bedding on California dairies. | The distribution of coliform organisms on three California dairies which use a system of automatic flushing of alley ways and composted, recycled manure solids as free stall bedding for utilization of waste was studied. There was a wide distribution of Escherichia coli, Klebsiella, and Enterobacter and to less extent C... | 361,769 | [
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Inhibition of the immune response by membrane-bound antibody. | Cells from the spleens of "normal" swine, which were pretreated with pronase to remove surface membrane-bound immunoglobulin, gave an enhanced hemolytic plaque-forming cell response to sheep red blood cells in vitro in comparison with untreated controls. The enhancement could be abrogated by preincubating pronase-treat... | 361,889 | [
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Influence of pili on the virulence of Proteus mirabilis in experimental hematogenous pyelonephritis. | The ability of heavily and lightly piliated Proteus mirabilis to infect the renal parenchyma was compared in a model of hematogenous pyelonephritis. Cortical abscesses occurred in 13 of 24 rats injected with lightly piliated P. mirabilis but in none of 24 rats challenged with heavily piliated organisms (P less than 0.0... | 361,900 | [
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Endotoxin-induced interruption of early pregnancy in the rabbit. | Endotoxin derived from Salmonella enteritidis (Boivin) completely interrupted pregnancy in the rabbit when given as a single dose (10 or 20 microgram/kg) intravenously on Day 4 or Day 8 of pregnancy. Indomethacin (2 or 10 mg/kg) was unable to prevent this effect. | 361,951 | [
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Extraction of glycoproteins during tissue preparation for electron microscopy. | The extraction of glycoproteins labelled with 3H or 14C precursors: fucose and glucosamine, has been compared during processing of rat liver for transmission electron microscopy. Using 14C labelled fucose, approximately 6% of labelled macromolecules were extracted during processing including 3% during glutaraldehyde fi... | 361,960 | [
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Drug resistance of Escherichia coli isolated in Nepal. | We collected Escherichia coli strains from 59 Nepalese porters in 1971 and surveyed for their drug resistance. Drug-resistant E. coli strains were isolated from four porters. (TC. CM. SM. SA. APC.)-resistant strains were isolated from two porters and SA- or APC-resistant strains were isolated from each of the others. T... | 362,028 | [
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... |
Radioimmunoassay for urinary renal tubular antigen: a potential marker of tubular injury. | A human proximal renal tubular epithelial antigen (designated HRTE-1) was isolated and purified from a crude tubular preparation (Fx1A) by a process of salt fractionation, DEAE anion-exchange chromatography, and Sephadex G-200 gel filtration. Utilizing 125I-HRTE-1 and a rabbit antiserum specific for the proximal tubula... | 362,038 | [
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[The agar culture of the leucopoietic stem cell (CFU-C) and its stimulation (author's transl)]. | This review summarizes the different in vitro culture techniques of the leukopoietic stem cell. Mainly the results obtained by the system of Pluznik and Sachs and Bradley and Metcalf are described apply with semisolid agar and its modification by Iscove using methylcellulose. Furthermore, recently published modificatio... | 362,052 | [
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A procedure for obtaining thin sections of undercalcified bone biopsies embedded in methyl methacrylate. | A complex of techniques is described, including a specially designed mould and a method for flat mounting of the sections, enabling to obtain well-stretched and undamaged thin sections of undecalcified bone biopsies. Apart from a gain in polymerisation time, a clear advantage of the special mould is a more favorable te... | 362,134 | [
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Rubella vaccination in Australia: 2. Experience with the RA27/3 rubella vaccine and results of a double-blind trial in schoolgirls. | RA27/3 rubella vaccine (Almevax) was used for the first time in Australia. The seroconversion rate was similar to that seen with Cendehill vaccine (Cedevax), but there were fewer subjects with low antibody titres after Almevax vaccine. Although Almevax vaccine was associated with a significantly higher incidence of sor... | 362,141 | [
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Genetic control of invertase formation in Saccharomyces cerevisiae. II. Isolation and characterization of mutants conferring invertase hyperproduction in strain EK-6B carrying the SUC3 gene. | Invertase formation in the yeast Saccharomyces cerevisiae is subject to repression by hexoses in the growth medium. Mutagen-induced (ethyl methanesulfonate or N-methyl-N-nitro-nitrosoguanidine) invertase hyperproducer mutants have been derived from the SUC3 MAL3 strain EK-6B by selecting for their ability to grow on me... | 362,157 | [
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[Methods for the demonstration of the basal membrane of the glomerular capillaries]. | Author for the demonstration of the basal membrane of the glomerular capillaries recommends oxidation with periodic-acid followed by treatment with potassium-metabisulfite and staining with resorcin-fuchsin, or impregnation with silver-nitrate solution in sodium borat. | 362,174 | [
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The relationship between mutagenicity and carcinogenicity of some nitrosamines. | The carcinogenicity and mutagenicity of 26 nitrosamines were compared to help validate the predictability of a short-term in vitro test. 80% of the compounds showed agreement between the two characteristics, while 20% did not. Of the latter group, 8% were false positives and 12% were false negatives. | 362,177 | [
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Induction of gene conversion in Saccharomyces cerevisiae by the nitrofuran derivative furylfuramide (AF-2). | The nitrofuran derivative furylfuramide (AF-2) is known to be both mutagenic and carcinogenic in a number of test systems. In this report we show that AF-2 can also induce gene conversion in diploid yeast in a manner dependent on both duration and concentration of treatment. | 362,196 | [
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0.02620278,... |
Treatment of chronic oral candidiasis with clotrimazole troches. A controlled clinical trial. | Twenty patients with chronic oral candidiasis were assigned by random allocation to a two-week course of either 10-mg clotrimazole buccal troches or placebo taken five times daily in a double-blind clinical trial. Each of the 10 recipients of clotrimazole had marked regression of symptoms and mucosal lesions, and in ni... | 362,197 | [
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... |
Baclofen for spasticity in multiple sclerosis. Double-blind crossover and three-year study. | Baclofen is a safe and effective means for treating spasticity associated with multiple sclerosis. We found no toxic effects on hepatologic, hematopoietic, or renal function, acutely or for over 3 years of follow-up. A statistically significant reduction was noted in frequency of spasms, and clonus, and there was impro... | 362,234 | [
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0.3121442,
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[Efficacy of diagnostic measures in colonic carcinoma]. | It has been tried to ascertain the comparative value of the different diagnostic measures with regard to colorectal cancer. On the basis of the results achieved, the addition of the Hämoccult test (if this has not yet been done), of the rectoscopy and of endoscopic polypectomy to the programme of preventive medicine is... | 362,285 | [
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0.0435613,
0.05810135,... |
[Clinical and immunological studies with OK-432 (Streptococcus pyogenes) on immunotherapy in cancer patients]. | In a phase I study, the bacterial vaccine OK-432 (streptococcus pyogenes) was investigated in eight patients with advanced malignant tumors. Besides a fever reaction after i.v. application no toxic side effects were observed. Additionally, its therapeutic effectiveness could be demonstrated by i.v. and local therapy. T... | 362,287 | [
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0.5771428,
0.2449173,
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Immunopathogenesis of chronic periapical lesions. A review. | The pathogenesis of periapical lesions has not been fully elucidated. Currently, the possibility of its being an immunologic phenomenon is receiving much attention. This article presents a review of the literature concerning immunologic reactions which may involve periapical lesions. It appears that antigen-antibody co... | 362,319 | [
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[B-streptococci infection in the newborn (author's transl)]. | The authors describe their experiences with the treatment of 3 newborns with meningitis due to B-streptococci,, and give a review of the problems of etiology, clinical symptoms, diagnosis and therapy of infections with B-streptococci in newborns. Furthermore, the article deals withthe frequency of the ocurrence of thes... | 362,350 | [
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0.2668703,
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0.058... |
Urinary tract infection presenting with jaundice. | Jaundice was the presenting feature in an 8-year-old girl suffering from urinary tract infection (UTI) due to Escherichia coli. The jaundice cleared with the cure of the infection. The mechanisms of jaundice complicating UTI are discussed, and the importance of urine culture in infants and children with jaundice is str... | 362,366 | [
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... |
[Generalised cortical hyperostosis. One case (author's transl)]. | Generalised cortical hyperostosis, a case of which is reported here, was distinguished from other condensing osteopathies by Van Buchem in 1955. It is characterised by a fairly special facial dysmorphia, associated with osteocondensation of the skull, spine, flat bones and the cortex of the long bones of the limbs. The... | 362,376 | [
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0.03398832,
0.... |
Treatment of total loss of the Achilles tendon by skin flap cover without tendon repair. | We present two cases of conservative treatment of total loss of the Achilles tendon. In our opinion the functional result is acceptable, without tendon grafting. The action of the sural muscles is transmitted through scar underlying the pedicled flaps used to resurface the wounds. | 362,438 | [
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0.0092894,
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0.03396785,
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-0.04551214,
-0.3051969,
-0.3609253,
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0.005533759,
0.1400145,
-... |
The effects of pre-admission antibiotics on the bacteriological diagnosis of pyogenic meningitis. | To assess the effects of pre-admission antibiotics on the accuracy of bacterial diagnosis in pyogenic meningitis, the case records of 154 patients admitted to an infectious diseases unit during a 10-year period (1966-1975) were reviewed. The causative organism was identified in 140 patients (91%). Although 63 patients ... | 362,513 | [
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0.0151043,
0.08998... |
Typing of group B streptococci from the throat and urogenital tract of females. | Group B streptococci were isolated from the urogenital tract of 54 of 168 patients (32%) examined at a gynecological outpatient department. 11 (7%) of the patients were group B throat carriers. In contrast to the frequency of type III group B steptococci in the urogenital tract (41% of group B streptococcal carriers) o... | 362,515 | [
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Plasma cortisol levels in normal volunteers receiving either betamethasone valerate or desoximetasone by topical application. | Desoximetasone (Topisolon; Hoechst), a new topical steroid, and betamethasone 17-valerate were compared with respect to their effects on hypothalamic-pituitary-adrenal function as evidenced by plasma cortisol concentrations. Three grams of each test preparation were applied daily for 21 days to intact skin of the ventr... | 362,568 | [
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[Utilization of clinical biochemical examination methods with obese children for establishing the use and assessment of the effectiveness of comprehensive therapy]. | A broadened procedure to be used in examining abese children are described. These include an analysis of the history data according to specially worked out schemes, the determination of the basal metabolism and energy expenditures of the naturt of fat deposition, characteristics of the lipids metabolism and the coeffic... | 362,709 | [
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Fermentation, isolation, and biological activity of maduramycin: a new antibiotic from Actinomadura rubra. | In a continuing search for new antibiotics, the species Actinomadura rubra (Sveshnikova et al.) J. Meyer et M. Sveshnikova 1974 (strain IMET 13001) was found to produce a red pigment with indicator properties, designated maduramycin. The pigment (C28H22O10; m.w. 518 m/e-; m.p. 305--310 degrees C (dec.); UVmax 225.307 n... | 362,738 | [
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0.3115291,
0.7069783,
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The pathophysiology and clinical aspects of hypercalcemic disorders. | FOR THE PURPOSES OF THIS REVIEW, THE VAST AND INCREASINGLY COMPLEX SUBJECT OF HYPERCALCEMIC DISORDERS CAN BE BROKEN DOWN INTO THE FOLLOWING CATEGORIES: (1) Physiochemical state of calcium in circulation. (2) Pathophysiological basis of hypercalcemia. (3) Causes of hypercalcemia encountered in clinical practice: causes ... | 362,722 | [
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0.07877383,
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0.1647272,
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0.1955309,
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... |
[Balzac and the limits of psychology]. | In contradiction to the general meaning that Balzac belongs to one of the first representative authors, who described their figures according to the assumptions of motivational psychology--including psychoanalytic, i. e. subconscious motivation--the Ref. gives proof, that Balzac has overcome these limited premises of a... | 362,746 | [
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0.3670293,
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[On the usefulness of bone scintigraphy for detecting loosening of articular prostheses (author's transl)]. | The most important complication of articular substitution is the loosening of the prostheses as a result of permanent overstraining, trauma, chemical or infectious noxae. The value of bone scintigraphy in the diagnosis of loosening of the endoprothesis was examined in 53 articular prostheses (49 hip joints and 4 knee j... | 362,752 | [
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0.04063146,
0.1906193,
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0.1313569,
... |
[Allogenic transplantation of sterilised bones and halfjoints (author's transl)]. | The bones and halfjoints were gained under non-sterile conditions. They were sterilised using 1% formaldehyde solution and preserved with 2% formaldehyde--sugar solution or 50% honey solution. 102 allogenic transplants were performed in 100 patients. The results are very satisfying. The method described is effective, o... | 362,764 | [
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0.2086796,
0.2997454,
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0.10727... |
[Acute arterial obstructions and emergencies in vascular surgery (author's transl)]. | Acute arterial obstruction due to embolism or thrombosis require surgery within 6 hours in case of complete ischaemia. The removing of the occluding material can be done in every hospital under local anaesthesia using a Fogarty-catheter. Reconstruction of injured arteries must be accomplished immediately after prelimin... | 362,765 | [
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... |
Plasma concentrations of diazepam and N-desmethyldiazepam in newborn infants after intravenous, intramuscular, rectal and oral administration. | Five newborn infants (birth weight 2900--3600 g) were given diazepam (Valium, LaRoche) for convulsive disorders in 4 equal doses intravenously, intramuscularly, rectally and orally with at least 24 hours intervals. Three infants were given doses of 1 mg diazepam/kg body weight, and 2 0.5 mg/kg. The parenteral solution ... | 362,801 | [
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0.1943122,
0.3213211,
0.5148639,
0.1944667,
-... |
Structural changes in kidneys of patients with oliguric extracapillary glomerulonephritis during immunosuppressive therapy. | Structural changes in kidney biopsies were investigated from five patients with primary oliguric extracapillary glomerulonephritis in whom the renal function was adequately maintained during extended combined immunosuppressive treatment. The most important structural change was a pronounced decrease in the number of cr... | 362,806 | [
0.1610422,
0.3268952,
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0.07056456,
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0.07060001,
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0.112212,
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0.1355309,
0.1161042,
0.179883,
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0.1505139,
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... |
Evidence for non-specifically bound IgG in human tumours. | Heat eluates of homogenized human malignant and normal tissues were prepared using the continuous flow elution technique. IgG antibodies to rabbit erythrocytes served as marker antibodies for non-specifically bound IgG. Eluates of all of the 13 malignant tumours tested contained IgG. Most were eluted at 56C, but consid... | 362,816 | [
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0.3286088,
0.2569243,
0.2107209,
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... |
Plasma vasopressin in ethanol intoxication and hangover. | The effect of ethanol intoxication and hangover on immunoreactive plasma arginine vasopressin (AVP) concentration was studied in 7 healthy supine men in controlled clinical conditions. In 6 subjects plasma AVP increased above control values at the time of maximal blood ethanol concentration. The highest AVP values were... | 362,827 | [
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0.24057,
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0.431955,
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0.006282452,
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0.2736025,
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-0... |
Results of a clinical trial with a Dermatophagoides pteronyssinus tyrosine adsorbed vaccine. | Twenty-eight patients were included in a double-blind placebo-controlled study of a vaccine containing tyrosine-adsorbed Dermatophagoides pteronyssinus antigen (Migen(R)). The aim of the trial was to show the efficacy and safety of Migen as a 6-injection course, with or without a follow-up course of 6 maintenance doses... | 362,875 | [
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0.1294221,
0.4220038,
0.04435097,
0.3123383,
0.3805124,
0.02577952,
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... |
The pathogenesis of respiratory syncytial virus infection in cotton rats. | The cotton rat is susceptible to respiratory synctial virus infection in both the upper and lower portions of the respiratory tract. Virus replicates to high titer in the nose and lungs and to relatively low titer in the trachea. Immunofluorescence studies demonstrated viral antigen in the nasal epithelium and the bron... | 362,946 | [
0.1266284,
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0.1238186,
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... |
Immunologic studies in Holstein-Friesian cattle: an immunocompetence profile. | An immunocompetence profile has been developed for Holstein-Friesian cattle. In vitro and in vivo immunoassays were used to determine (1) the percentage of peripheral blood lymphocyte (PBL) subpopulations bearing surface-membrane receptors for sheep erythrocytes, complement, or surface immunoglobulin; (2) the PBL blast... | 362,996 | [
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0.2684285,
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0.1226809,
-0.06165204,
... |
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