title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Starvation diabetes in the rat: onset, recovery, and specificity of reduced responsiveness of pancreatic beta-cells. | A 24-h starvation markedly diminished the stimulant action of 8 mM glucose on insulin secretion from isolated perifused rat islets of Langerhans. The response to a supramaximal glucose stimulus (27.5 mM) remained normal, but prolonged fasting (48 or more) also reduced its efficacy. Refeeding of 24-h fasted animals resu... | 374,069 | [
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An evaluation of some theories of the mechanism of aging. | Two theories of aging are considered in this review. Although there exists substantial experimental evidence in support of the somatic mutation and error catastrophe hypotheses, several experiments have been published which are extremely difficult to reconcile with these models, at least in their simplest forms. These ... | 374,185 | [
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Effectiveness of etamsylate in intrauterine-device menorrhagia. | 107 parous women wearing Szontágh-type IUDs were treated with either etamsylate or placebo tablets by a double-blind technique with random allocation. The length of the cycles, the duration of menstrual bleeding and the amount of bleeding were analyzed. Etamsylate treatment favourably influenced menstrual bleeding in I... | 374,202 | [
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Modification of kidney immunogenicity with standard Concanavalin A and its subfractions. | Pretreatment of kidneys with purified Concanavalin A (25 mg/L) allowed for a significant prolongation of survival after allotransplantation in minimally immunosuppressed mongrel dogs. Kidneys pretreated with standard Concanavalin A, impure fraction or the lipopolysaccharide had no prolongation of survival. In fact, the... | 374,243 | [
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Lymphocyte binding of fluid phase mouse C3b. | Isolated fluid phase mouse C3b adhered to human and to mouse lymphocytes. On human, but not on mouse cells it could be stained by fluoresceinated F(ab')2 anti-mouse C3. Binding to mouse cells was, however, shown by inhibition of C3-dependent rosette formation and by direct staining with fluorescein-conjugated C3b (FITC... | 374,253 | [
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Preserved foods as possible cancer hazards: WA rats fed salted fish have mutagenic urine. | Six batches of food traditionally and commonly consumed by southern Chinese, including two samples of dried shrimps and four samples of different species of salted fish, were tested for mutagenic properties using Salmonella typhimurium TA98 and TA1000. Mutagenic activities toward both tester strains were found in all p... | 374,286 | [
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[Swellings of the cheek from sialosis (author's transl)]. | The term sialosis was introduced by Rauch (1956) and was associated with a symmetrical, painless, recurrent enlargement of the salivary glands. Included among the sialoses were non-inflammatory and inflammatory diseases of the salivary glands. A more recent definition still in use today was made by Seifert (1960) and i... | 374,314 | [
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Occurrence of 1-methyladenosine and absence of ribothymidine in transfer ribonucleic acid of Mycobacterium smegmatis. | The minor base composition of Mycobacterium smegmatis tRNA has been studied. Thin-layer chromatographic patterns of a ribonuclease T2 digest of mycobacterial tRNA indicated the presence of appreciable amounts of 1-methyladenosine (which is commonly present only in eucaryotic tRNA), dihydrouridine, and 7-methylguanosine... | 374,335 | [
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Effect of dna mutations on the replication of plasmid pSC101 in Escherichia coli K-12. | Escherichia coli strains with mutations in genes dnaB, dnaC, and dnaG were tested for their capacity to replicate pSC101 deoxyribonucleic acid (DNA) at a nonpermissive temperature. Only a small amount of radioactive thymine was incorporated into pSC101 DNA in the dna mutants at 42 degrees C, whereas active incorporatio... | 374,337 | [
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Mapping of ilvO loci of Escherichia coli K-12 with bacteriophage lambda dilv. | A set of lambda dilv phage have been used in a deletion mapping procedure to determine the location of two previously characterized ilvO alleles. In contrast to earlier conclusions derived from three-factor crosses and episome-shortening techniques with phage P1, the order found is ilvG-ilvO-ilvEDA. A three-factor cros... | 374,344 | [
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Alteration of the fatty acid composition of Escherichia coli by growth in the presence of normal alcohols. | The addition of normal alcohols in the series n-butanol to n-octanol to cultures of Escherichia coli ML308 grown on defined or lipid-free medium (at 17, 27, and 37 degrees C) caused an alteration in the fatty acid composition of this organism: the ratio of saturated to unsaturated fatty acids increased. Changes in the ... | 374,359 | [
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Length growth of two Escherichia coli B/r substrains. | Length growth of synchronized Escherichia coli B/r substrain A (ATCC 12407) and B/r substrain F26 (Thy his) was followed with an electron microscope. Cells were grown with doubling times (tau) of 60 min (B/rA) and of 82 and 165 min (B/rF26). Different length growth patterns were found for the two substrains. In B/rF, t... | 374,363 | [
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Relationship between deoxyribonucleoside triphosphate pools and deoxyribonucleic acid synthesis in an nrdA mutant of Escherichia coli. | A shift to 42 degrees C in an nrdA mutant causes a decrease in deoxyribonucleic acid synthesis without a concomitant decrease in deoxynucleotide triphosphate pools. | 374,367 | [
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Gene copy number effects in the mer operon of plasmid NR1. | The level of resistance to Hg2+ determined by the inducible mer operon of plasmid NR1 was essentially the same for three gene copy number variants in Escherichia coli, less in Proteus mirabilis, and intermediate in P. mirabilis "transitioned" to a high r-determinant gene copy number. Cell-free volatilization rates of r... | 374,374 | [
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The purification of orotidine-5'-phosphate decarboxylase from yeast by affinity chromatography. | We have prepared an affinity column for the purification of orotidine-5'-phosphate decarboxylase from yeast. The column effects a 3200-fold purification from yeast homogenate in one pass; simple additional steps produce enzyme that has been purified 6700-fold and is not contaminated by any other protein that can be det... | 374,408 | [
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Purification of the o-dianisidine peroxidase from Escherichia coli B. Physicochemical characterization and analysis of its dual catalatic and peroxidatic activities. | Extracts of aerobically grown Escherichia coli B exhibit both catalase and dianisidine peroxidase activities. Polyacrylamide gel electrophoresis demonstrates two distinct catalases which have been designated hydroperoxidases I and II (HP-I and HP-II) in order of increasing anodic mobility. HP-I has been purified to ess... | 374,409 | [
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A comparison of thiomersal and 50% alcohol as preservatives in urinary cytology. | The efficacy of 50% ethyl alcohol and of thiomersal as preservatives in urinary cytology were compared. In both methods over 80% of the cells were sufficiently well preserved after three days to allow cytomorphological evaluation, and over 50% on the seventh day. In the specimens without preservative, only 54% and 28% ... | 374,426 | [
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Effect of autogenous marrow and calcitonin on reactions to a ceramic. | The effect of autogenous marrow and calcitonin on reactions to a tricalcium phosphate ceramic was studied by subcutaneous implantation in rats. No bone formation was evident in association with uncoated and calcitonin-coated ceramic. At four weeks and thereafter bone formation was evident in association with all marrow... | 374,436 | [
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An automated microscope for quantitative cytology combining television image analysis and stage scanning microphotometry. | This paper describes an automated microscope developed for operation in conjunction with the Leyden Television Analysis System. It features automated control of magnification, illumination, movement of scanning stages, and fine focus. These functions are controlled by means of a microcomputer. This enables a flexible d... | 374,568 | [
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A practical application of computer pattern recognition research: the Abbott ADC-500 differential classifier. | The ADC-500 is a new blood cell differential classifier manufactured by Abbott Laboratories. It performs 500-cell leukocyte differentials on both normal and abnormal cells, evaluates red cell morphology and estimates platelet sufficiency at a rate of 40 to 50 samples per hour in stand-alone operation. The ADC-500 syste... | 374,571 | [
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Automated quantitative analysis of single and double label autoradiographs. | A method for the analysis of silver grain content in both single and double label autoradiographs is presented. The total grain area is calculated by counting the number of pixels at which the recorded light intensity in transmission dark field illumination exceeds a selected threshold. The calibration tests included a... | 374,578 | [
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Light scattering with stream-in-air flow systems. | Both forward angle and 90 degrees light-scattering measurements have been used for cell sizing with stream-in-air flow systems with very little theoretical base for the measurements. Mie theory calculations are compared with measurements on plastic microspheres. Detector response for homogeneous spheres is shown to be ... | 374,583 | [
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Dual-laser flow cytometry of single mammalian cells. | An improved dual-laser flow cytometric system for quantitative analysis and sorting of mammalian cells has been developed using a low-power argon and high-power krypton laser as illumination sources, thus permitting the excitation of fluorescent dyes having absorption regions ranging from the ultraviolet to infrared. C... | 374,585 | [
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Cell differentiation based on absorption and scattering. | Improvements of the flow system allow calibrated cell length measurements down to less than 2 micron at a very high rate. An optical index match to plane viewing windows perpendicular to the optical axis in the flow system keeps the axial symmetry for forward scattered light. Cell size, axial light loss and scattering ... | 374,602 | [
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Flowcytometric evaluation of the DNA distribution in isolated pancreatic islets from normal and diabetic mice. | Pancreatic islets from C57BL/KsJ-db/db, and +/+ mice were isolated by collagenase. After isolation the islets were transferred to a hypotonic ethidiumbromide solution with 0.3% of the detergent Nonidet P40. After vortexing, the samples were analyzed in a BioPhysics Cytofluorograf 4802A. The DNA histograms were divided ... | 374,603 | [
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Efficient interaction for automated chromosome analysis using asynchronous parallel processes. | It is likely that any practical automated chromosome analysis system will be interactive. To prevent long pauses in the stream of operator interactions, it is necessary, if using standard computer hardware, to configure for asynchronous and parallel operation. A system is presented which uses several computer processor... | 374,606 | [
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Flow cytometry of human gynecologic specimens using log chromomycin A3 fluorescence and log 90 degrees light scatter. | Flow cytometry and electronic cell sorting are being investigated to screen gynecologic specimens for cervical neoplasia. Cellular DNA content is quantitated by Chromomycin A3 fluorescence and cell size is quantitated by 90 degrees light scatter; the logarithms of the measured intensities are used to produce a two para... | 374,623 | [
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The study of Escherichia coli proteases. Intracellular serine protease of E. coli-an analogue of bacillus proteases. | Two serine proteases in extracts of Escherichia coli grown to stationary phase were purified to homogeneity using affinity chromatography on gramicidin S-Sepharose 4B. One enzyme was closely related to, if not identical with, the 'trypsin-like' protease II of E. coli. The other was capable of cleaving the subtilisin ch... | 374,683 | [
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0.09225165,
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0.02368812,
0.116492,
0.013909,
0.4508898,
0.2859813,
-0.0764005,
... |
Cellular hypersensitivity to brain antigen in children of a family with hereditary ataxia. | Sensitisation to brain antigen was demonstrated in eight of 24 clinically normal first generation children in a family with hereditary ataxia. This ratio is consistent with that expected in a dominantly inherited condition. It suggests that immunological reactivity may precede the clinical expression of disease, with i... | 374,687 | [
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0.1105151,
0.02173999,
... |
The prosthodontic rehabilitation of selected adults class III malocclusions. | In a previous paper (Murray 1978) some of the problems associated with currently employed preoperative assessment aids were discussed. Techniques were described for establishing the occlusal vertical dimension of occlusion, and support for the upper lip. The incorporation of these treatment planning aids in the prostho... | 374,697 | [
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0.0714833... |
Periodontal status of patients with reduced immunocapacity. | The periodontal status of patients with reduced immunocapacity was assessed. Gingival inflammation, periodontal destruction, and plaque accumulation were compared in three groups--renal transplant patients, dialysis patients, and normal individuals. The levels of all parameters were similar in the three groups indicati... | 374,705 | [
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... |
Tooth staining effects of an alexidine mouthwash. | The primary purpose of this study was to determine the amount of tooth staining produced by an alexidine mouthrinse. One hundred and eighty subjects rinsed twice daily for 1 month with either 15 ml of alexidine (0.035%) or a placebo solution. Prior to the study, the subjects were classified according to their smoking, ... | 374,706 | [
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0.3528044,
0.01929854... |
Repair of porcelain-fused-to-metal restorations. | Three techniques have been described which may be used to repair many porcelain-fused-to-metal restorations. These techniques provide an avenue of repair for extensive porcelain-fused-to-metal restorations without remaking the entire prosthesis. The success of the overlay and pin-retained ceramo-metal repairs should be... | 374,722 | [
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0.01219002,
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0.195486,
0.03210576,
... |
Examination of living Sertoli cells in normal and hypospermatogenic men. | The functional state of living Sertoli cells can be assessed by using transillumination and phase-contrast microscopy. In tissue from hypospermatogenic men the Sertoli cells contained more lipid droplets than in normal cases and sometimes whole degenerative cells. | 374,728 | [
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0... |
[Language of physicians' ECG conclusions]. | The elaboration of a standardized language for expressing the ECG diagnosis is of great practical importance and is necessary for the creation of a system of automatic treatment of the electrocardiosignal. A language is suggested for the ECG findings according to the changes in the ECG contour and disorders of the card... | 374,825 | [
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... |
[Alpha 1 antitrypsin deficiency in childhood]. | The author deals with the clinical importance of the alpha-1-antitrypsin deficiency in form of a survey with tabular representation of own cases. Alpha-1-antitrypsin as an inactivator of proteolytically effective enzymes essentially participates in the localised effect of proteinases. A genetically determined decreased... | 374,827 | [
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0.4400795,
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... |
[Pilocarpin eye drops with a novel Pilocarpin polymeric salt (author's transl)]. | A new pilocarpin salt was obtained by chemically linking pilocarpin to a polymere substance. By galenic processing to the respective emulsion, eye drops containing this pilocarpin salt were produced, which enable a retarded pilocarpin delivery in vitro. With respect to glaucoma therapy, clinical tests showed that frequ... | 374,847 | [
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0.1277481,
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0.2345827,
0.01298437,
0.0266938... |
Reversal of protection by light of the ethidium bromide induced petite mutation in yeast. | An intermediate in the ethidium bromide (EB) induced petite mutation pathway may be destabilized by daylight light to cause a reversion to the normal grande phenotype. Starved cells preincubated in the dark for up to 6 h with 100 microgram/ml EB could be reverted to grandes after one hour of light exposure, whereas sim... | 374,999 | [
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0.3316945,
0.2096505,
0.615963,
0.01167716,
0.004... |
The DNA repair capability of cdc9, the Saccharomyces cerevisiae mutant defective in DNA ligase. | The cell cycle mutant, cdc9, in the yeast Saccharomyces cerevisiae is defective in DNA ligase be deficient in the repair of DNA damaged by methyl methane sulphonate. On the other hand survival of cdc9 after irradiation by gamma-rays is little different from that of the wild-type, even after a period of stress at the re... | 375,019 | [
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Evaluation of a modified dye pour-plate auxanographic method for the rapid identification of clinically significant yeasts. Comparison with two commercial systems. | A modified dye pour-plate auxanographic (DPPA) method for the presumptive identification of medically important yeasts was evaluated, in a comparative study with a conventional procedure, the API 20C clinical yeast system (Analytab Products Inc.), and the Uni-Yeast-Tek (UYT) system. The 174 coded clinical isolates were... | 375,051 | [
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0.02319913,
... |
Fungal peritonitis and malignancy: report of two patients and review of the literature. | Two patients developed isolated Candida albicans peritonitis in association with intraabdominal malignancy. Although additional factors predisposing to the development of fungal peritonitis were present, we postulate that tumor-related local factors permitted fungi to cross the gut wall and to enter the peritoneum, whe... | 375,052 | [
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0.346661,
-0.0... |
Origins and control of stereotyped movements. | A large number of retarded individuals exhibit repetitive and rhythmical movements of a highly stereotyped character. Common forms of these behaviors include body rocking, head nodding, hand waving, head banging and so on. Such behaviors are distinguished by their apparently maladaptive and excessive nature. The freque... | 375,065 | [
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-0.1410528,
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Autoantibodies to gastrin-producing cells in antral (type B) chronic gastritis. | Autoantibodies that react exclusively with the gastrin-secreting cell of human antrum have been detected by immunofluorescence in eight of 106 patients with histologic evidence of chronic atrophic gastritis, Type B, involving mainly the antrum. These antibodies were of the IgG class and of low titer. However, follow-up... | 375,090 | [
-0.02698614,
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0.04621331,
-0.1070892,
... |
A seven-day volumetric spore trap for use within buildings. | The Burkard Volumetric spore trap, designed to operate for seven days continuously in the field, was modified to sample still air within buildings. The efficiency with which spores of Lycopodium clavatum and Agaricus bisporus were trapped at two rates of suction was determined. Spore distribution within traces and depo... | 375,094 | [
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0.07768175,... |
Guidelines for supervised wound care by emergency nurse practitioners. | Nearly 10 million patients with traumatic lacerations are treated annually in Emergency Departments in the United States. Since these wounds do not usually pose a threat to the patient's life, they assume a lower level of priority than emergent conditions. Consequently, treatment of patients with lacerations is often d... | 375,130 | [
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0.20... |
2'-Deoxy-2'-fluorouridine-5'-triphosphates: a possible substrate for E. coli RNA polymerase. | dUflTP was tested as substrate in the E. coli RNA polymerase system using poly(dAT) as template. dUflTP could replace UTP when Mn++ was utilized as divalent cation instead of Mg++. The level of transcription with the fluoro analog was then 55% of that with UTP. | 375,193 | [
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0.075... |
In vitro methylation of yeast tRNAAsp by rat brain cortical tRNA-(adenine-1) methyltransferase. | Rat brain cortices from young animals contain large amounts of tRNA (adenine-1)methyltransferase(s). The enzyme(s) can methylate E. coli tRNA and to a lower degree yeast tRNA. Among yeast tRNA species which can be methylated we have selected tRNAAsp as a substrate for the brain enzyme. The digestions of in vitro methyl... | 375,195 | [
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Cloning, mapping and expression of the genetic determinant that encodes for the K88ab antigen. | The K88 antigen, a plasmid-specified virulence factor of E. coli involved in porcine neonatal diarrhoea, is often found to be associated with the ability to metabolize raffinose (Raf). Plasmid pRI8801 (51 megadalton) was used to clone the determinants of K88 and Raf with the vector pBR322. K88 was found to be encoded b... | 375,197 | [
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0.05510287,
-0.2556844... |
Localization of the decoding region on the 30S Escherichia coli ribosomal subunit by affinity immunoelectron microscopy. | The decoding region of the Escherichia coli ribosome has been localized by affinity immunoelectron microscopy. Valyl-tRNA1Val, derivatized at the alpha-amino end with the dinitrophenyl group, was bound to the ribosomal P site of 70S ribosomes and crosslinked specifically to 16S RNA by 310- to 325-nm irradiation. Previo... | 375,223 | [
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0.2605011,
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0.2514133,
0.4249683,
0.1906673,
-0.01679056... |
Bacteriophage f1 infection of Escherichia coli: identification and possible processing of f1-specific mRNAs in vivo. | [3H]Uracil-pulse-labeled RNA from Escherichia coli infected with f1 bacteriophage was fractionated on polyacrylamide gels containing urea. Eight phage-specific RNA species were present with approximate lengths ranging from 2100 to 400 nucleotides. The amount of the seven largest species was increased when the infected ... | 375,228 | [
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0.3446254,
0.0007262205,
-0.2243... |
Soluble precursor of an integral membrane protein: synthesis of procoat protein in Escherichia coli infected with bacteriophage M13. | Prior to virus assembly, the major coat protein of coliphage M13 is an integral protein of the host cytoplasmic membrane. Coat protein synthesized in vitro is initially made with an NH2-terminal "leader peptide" of 23 amino acids and is termed "procoat." We now report that procoat is a biosynthetic precursor of coat pr... | 375,229 | [
-0.1191398,
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0.4876867,
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Complicated neck contracture treated with a pectoralis major myocutaneous flap. | A case is presented which demonstrates the use of a pectoralis major myocutaneous flap for repair in a heavily radiated neck and chest, with neck contracture and a tracheocutaneous fistula. | 375,273 | [
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0.3791718,
0.03168674,
0.13475... |
[Diagnosis and therapy of neurotic depressions]. | The causes of depressive syndroms differ from case to case. Frequently, the cause of disease cannot be reliably determined from the cross-sectional picture alone. Rather, it is necessary to give careful consideration to heredity, longitudinal analyses, and psychodynamics. The etiopathogenesis of neurotic depressions is... | 375,275 | [
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0.2116097,
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-0.1948474,
-0... |
Primary IgA glomerulonephritis and Schönlein-Henoch purpura nephritis: Clinicopathological and immunohistological characteristics. | A comparative analysis on clinicopathological and immunohistological characteristics was performed of 205 cases with primary IgA nephritis and 35 with Schönlein-Henoch purpura nephritis (purpura nephritis). Diagnostic criteria for primary IgA nephritis were set out so that IgA was either the most prominent immunoglobul... | 375,278 | [
0.3152187,
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0.1551683,
0.1520644,
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... |
Properties of antinuclear antibodies that cross-react with plasma membranes. | Certain human antinuclear antibodies (ANA) cross-react specifically with the surface membrane of human leucocytes. In the present work these cross-reacting (X) ANA could be eluted directly from viable leucocytes isolated from three patients. The plasma membrane antigen recognized by X-ANA appeared phylogenetically high... | 375,379 | [
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... |
Extrapituitary action of gonadotropin-releasing hormone: direct inhibition ovarian steroidogenesis. | Gonadotropin-releasing hormone (GnRH) and its agonistic analogs inhibited the follicle-stimulating hormone (FSH)-induced increase of estrogen and progesterone production in vitro by rat ovarian granulosa cells. Likewise, GnRH analogs inhibited FSH-induced changes in ovarian function in hypophysectomized rats in vivo. T... | 375,393 | [
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0.2459699,
0.01670542,
0.086903,
0.05633168,
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-0.4622237,
-0.0283509,
-0.4533461,
-0.02235478,
0.03671378,
-0.06113245,
-0.07644571,
0.1483238,
-0.054249... |
Preventing disruption of abdominal wounds. | The use of silver wire retention sutures requires added operating room time and expense, and it incurs the potential hazards of caught viscera, the possibility of more adhesions, leakage of intraperitoneal fluid through the exit wound, mild infection of exit wounds, and, on removal of the sutures, pain despite sedation... | 375,400 | [
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0.1734913,
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Transmission and scanning electron microscope preparations of the same cell culture. | A technique has been developed which allows transmission electron microscopy and scanning electron microscopy to be performed on the same cell culture sample. The technique uses the Costar 3,393 Leighton Tube containing a plastic insert, which does not stick to epoxy, for transmission electron microscopy. A cut piece o... | 375,470 | [
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0.2597959,
0.6152364,
0.2651142,
0.1711686,
... |
Relationship of B cell alloantibodies to renal allograft survival. | To define the relationship of donor-specific B lymphocyte alloantibodies to renal allograft survival, longitudinal serum samples obtained pre- and post-transplantation were examined for antibodies cytotoxic to donor B lymphocytes. Ten of 17 renal allograft recipients had antibodies to donor B lymphocytes but not T lymp... | 375,503 | [
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0.3678534,
0.2997195,
0.2403517,
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-... |
Full thickness skin graft urethroplasty for anterior urethral strictures. | Thirty-two free full thickness skin graft urethroplasties were performed over a thirty-nine-month period. Follow-up of more than six months was available in 27 patients. Results were good or fair in 26 patients (96 per cent). Only 1 patient has been classified as a failure and required reoperation. | 375,535 | [
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[Theoretical basis for and the results of using bone marrow-devoid spongy allografts in the surgery of tuberculous spondylitis in adults]. | Experimental studies over 189 animals have proved that spongy allografts, devoid of the bone marrow, possess high plastic properties, get very soon replaced with a newly formed bone tissue and reconstruct. Experimental and clinical findings advocate, the rationality of their use of antero-lateral spondylodesis in tuber... | 375,551 | [
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0.1870189,
0.4005089,
0.1910839,
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[Organ-preserving procedure and blood retransfusion in children with splenic ruptures]. | An analysis of anesthesiologic and surgical tactics in the treatment of children with spleen traumas proves the reliability and effectiveness of the blood retransfusion and of the principle of the organ-preserving interventions, according to the amount of the blood loss and the character of the spleen ruptures. In auth... | 375,553 | [
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0.4389059,
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0.02139165,
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[Results of modern syphilis serology in blood donors, at the same time a contribution to spontaneous healing of syphilis]. | 261 out of 336 845 blood donors have been shown to had undergone a syphilitic infection. About 52 per cent of these donors have had knowledge of their infection and of specific treatment of the disease. In about 43 per cent of the investigated cases the T. pallidum infection has had probably an inapparent course and he... | 375,603 | [
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0.4457538,
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... |
[Surgical obstetrics in past and presence (author's transl)]. | The history of surgical obstetrics is highlighted by discussing the historical development of forceps delivery, vacuum extraction, forceps vectis (application of a single blade only), embryotomy, and caesarean section operations. Finally present status of operative obstetrics is outlined from a modern point of view. | 375,621 | [
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0.2349097,
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Neonatal septicemia and perinatal risk factors. | Many methods for screening and prediction of neonatal septicemia have been tried. In this study a score, related to both perinatal risk factors and neonatal diseases, was tested upon healthy newborn infants, infants with septicemia and infants with other diseases. Statistical differences were found between infants with... | 375,667 | [
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0.3936733,
0.08967204,
0.03358686... |
Genetic transformation in Streptococcus sanguis. Distribution of competence and competence factors in a collection of strains. | Forty-one strains of Streptococcus sanguis (37 of serogroup H and four of the newly-described serogroup W) were examined semiquantitatively for genetic transformation with streptomycin as marker. The material comprised eight reference laboratory strains and 33 recent isolates. Eighteen strains (16 of serogroup H and tw... | 375,671 | [
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0.8392444,
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... |
Influence of O and K antigens on the surface properties of Escherichia coli in relation to phagocytosis. | Strains of Escherichia coli with different O and K antigens were investigated with respect to physicochemical surface characteristics and liability to phagocytosis. Using two-phase partitioning analysis for the surface characterization, three main groups of strains emerged: Group I (O1:K1, O2:K1, O3:K2ab) showing both ... | 375,674 | [
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0.4714677,
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0... |
Zinc supplementation in alcoholic cirrhosis. A double-blind clinical trial. | A double-blind clinical trial with zinc sulfate, 0.2 g three times daily, and a placebo was performed in 30 patients with biopsy-proven alcoholic liver cirrhosis. The disease was in a stable phase, and none of the patients showed evidence of a decompensated liver function. Parameters of liver function, taste acuity, da... | 375,690 | [
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0.288093,
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The antidepressant properties of mianserin and its effect on sleep. | Patients diagnosed as suffering from manic-depressive psychosis-depressed (ICD 296.2) were retained and randomly assigned to two groups, one receiving mianserin, the other placebo. For the pre-trial period and throughout the trial, patients' sleep was estimated by themselves and by nurses. Patients rated themselves on ... | 375,685 | [
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0.2441959,
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0.2034952,
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Influence of pharmacologic intervention and valvular heart disease on left ventricular ejection phase indices: a review. | Echocardiography represents an established noninvasive technique to evaluate left ventricular (LV) performance. The LV ejection phase indices may be divided into three categories: (1) volume-dependent, (2) circumferential, and (3) wall thickening. Since the latter two are not volume dependent, they are clinically more ... | 375,692 | [
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Peritubular capillary control of proximal tubule reabsorption in the rat. | Changes in peritubular capillary hydrostatic and oncotic pressures, which probably affect net interstitial pressure and, thus, the force on fluid movement across the tubule basement membrane, can modulate absolute proximal reabsorption rate (APR). To examine the relationship between APR and net interstitial pressure, w... | 375,749 | [
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From Clover to computer. Towards programmed anaesthesia? | The control of depth of anaesthesia has been viewed as a control-system problem the solution of which can involve both feedback and feedforward techniques. The nature of the problem in Clover's day and the solutions he found have been examined. A similar analysis has been made in respect of the modern anaesthetist. Fin... | 375,770 | [
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Cefazolin prophylaxis in head and neck cancer surgery. | This study evaluated the prophylactic use of cefazolin in reducing the incidence of infection in patients undetgoing cancer surgery where the upper aerodigestive tract was entered from the neck. A prospective, randomized, double-blind design was conducted in a single hospital. The patient was given placebo or cefazolin... | 375,802 | [
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0.0913... |
[Idiopathic hemochromatosis and gonadotropin secretion (author's transl)]. | 18 patients suffering from idiopathic hemochromatosis were studied. Plasma testosterone was stimulated by HCG. Basal plasma LH and FSH were significantly lower for the male group compared to healthy men. Lack of reponse of plasma LH and FSH after IV LHRH (100 microgram) was observed in 10 cases; among the patients with... | 375,805 | [
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0.06695606,
0.08492637,
0.4064544,
0.07332769,
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... |
[Plasmid-determined streptococcal resistance to antibiotics]. | The analysis of the genetic organization of the determinant ERLI by means of obtaining and studying the antibiotic sensitive mutants from the strain resistant to erythromycin and lincomycin provided experiment data in favour of the fact that inducable resistance to erythromycin and lincomycin determined by the plasmid ... | 375,817 | [
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0.2899942,
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0.3761166,
0.6592991,
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... |
[Experimental characteristics of the antileishmaniasis action of amphotericin B]. | The efficacy of amphotericin B powder of the Soviet production was studied as a therapeutic agent in experimental zoonotic leishmaniosis of the skin form of mice and hamsters. Amphotericin B was administered per os and its action was compared with that of monomycin injected subcutaneously (50 mg/kg). Amphotericin B in ... | 375,822 | [
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0.4513162,
0.1993089,
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... |
Presidential address: the woman in the case. Jane Todd Crawford, 1763--1842. | The 1978 Presidential Address of the Southern Surgical Association is dedicated to the wives of the members, past and present, in acknowledgment and appreciation of the enduring contribution that they have made to the quality and character of this association. | 375,854 | [
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0.2325552,
0.1588089,
-0.13649... |
Oropharyngeal candidiasis treated with a troche form of clotrimazole. | A randomized double-blind trial was conducted to assess the local effectiveness and safety of a troche form of clotrimazole in the treatment of oropharyngeal candidiasis in cancer patients. One half of the patients received one 10-mg troche and the other half received one 50-mg troche, five times a day for two weeks. C... | 375,858 | [
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0.08633561,
0.2894434,
0.1740578,
0.4288505,
-0.0025257... |
Mass culture of human corneal endothelial cells. | Human corneal endothelial cells have been grown in mass culture for the first time to our knowledge. Cultures from donors who were under 20 years of age grew well. Cells from older donors were difficult to grow or did not grow at all. Initial outgrowth usually began one week after explantation. After an initial lag pha... | 375,894 | [
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0.3167878,
0.4957727,
0.3454736,
0.04128841,
-... |
Modification of the immunogenicity and antigenicity of rat hepatoma cells. II. Mild heat treatment. | I.p. immunization with gamma-irradiated hepatoma cells induces resistance to s.c. tumour-cell challenge in syngeneic WAB/Not rats. Mild heat treatment of these cells (greater than 41 degrees C for 30 min) destroyed this immunoprotective effect, but did not abolish tumour-specific antibody production in treated rats. Th... | 375,964 | [
-0.09407603,
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0.3134049,
0.02143472,
0.1387365,
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0.1... |
Predominance of T lymphocytes in the dermal infiltrate of atopic dermatitis. | Tissue sections from diseased skin of sixteen patients with atopic dermatitis were investigated with haematoxylin-eosin and toluidine-blue staining, with direct immunofluorescence staining using FITC-conjugated antisera against IgG F(ab')2 and IgM, and with the indirect immunofluorescence method utilizing specific rabb... | 375,967 | [
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-... |
A mechanism for the hydroperoxide-mediated inactivation of prostacyclin synthetase. | Hydroxyl radical generation was demonstrated during heme-catalyzed decomposition of 15-hydroperoxy arachidonic acid. The hydroperoxide-mediated inactivation of prostacyclin synthetase seems to be related to the generation of this highly reactive species. A relationship between hydroperoxides and the hydroxyl radical ma... | 376,000 | [
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0.455923,
0.1907712,
0.2962726,
-0.14332... |
Aluminium foil as a wound dressing. | Aluminium foil has been found to be an extremely useful and painless way of dressing wounds prior to delayed skin grafting. However, it is not recommended for use on skin-graft donor sites as it delays epithelial healing. | 376,020 | [
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0.05572868,
-0.0092757... |
Value of bromocriptine in unexplained primary infertility: a double-blind controlled trial. | In a double-blind controlled study, 47 women with unexplained primary infertility were allocated at random to treatment with either bromocriptine 2.5 mg twice daily (24 patients) or placebo (23). Both groups showed a fall in serum prolactin concentrations but the reduction was much greater in the bromocriptine-treated ... | 376,036 | [
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0.1024961,
0.4013314,
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0.2058757,
-0.02337054,
-0.439724,
0.02795809,
-0.001005357,
-0.2547126,
0.0537259,
0.04106168,
0.3831797,
-0.1035858,... |
Restrictive antibiotherapy after renal transplantation. | Forty-two patients were followed up after 44 renal transplantations in an effort to evaluate possible benefits from the following protocol: systematic microbiologic and clinical surveillance, early and aggressive research for the cause of suspected infections, refusal to use prophylactic antibiotherapy, and selection o... | 376,078 | [
0.03324054,
-0.004973211,
-0.2427943,
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-0.1802998,
0.135041,
-0.2472564,
0.2741509,
0.2655205,
0.4069851,
-0.1293958,... |
Differentiation between benign and malignant human lymph nodes by means of immunologic markers. | A surface-marker assay combining immunofluorescence with anti-human immunoglobulin or anti-human brain serum (AHBS) and the formation of rosettes with untreated (E), antibody-sensitized (EA) and complement-coated (EAC) sheep erythrocytes was used to study mononuclear cell suspensions of human lymph nodes. The frequency... | 376,086 | [
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0.2114174,
0.1529272,
0.4639351,
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... |
Mechanism of action of diet as a carcinogen. | Stomach cancer in the United States has decreased over the last 50 years. It is still a major type of neoplasm in Japan, Eastern and Northern Europe, and parts of Latin America. Current concepts suggest that the reduction of gastric cancer in the U. S. stems from an increased consumption of foods with vitamin C on a ye... | 376,103 | [
-0.2060395,
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0.2907679,
0.2669135,
-0.2121734,
... |
Antibody-induced movement of common melanoma membrane antigens on the surface of unfixed human melanoma cells. | Antisera to common human melanoma antigens were obtained from melanoma patients receiving autologous immunization with their own irradiated cultured melanoma cells and Bacillus Calmette-Guérin. The antibody thus derived was used to detect common antigens on the plasma membrane of three different human melanoma cell lin... | 376,115 | [
-0.1309749,
-0.0834286,
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-0.06893425,
0.3343044,
0.6415628,
0.1363887,
-0.1236933,... |
Kinetics of cell kill by hyperthermia. | A review of published reports showed that there was surprisingly good agreement between different authors on the heat sensitivity of a particular cell line. For several cell lines, there was a marked difference in the heat of inactivation above 43 degrees (deltaH = 148 kcal/mol) and below 43 degrees (deltaH = 365 kcal/... | 376,117 | [
-0.3081542,
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0.1168975,
-0.2221588,
0.6603934,
0.6139334,
0.1596947,
-0.05787041,... |
Physical and biological aspects of fracture healing with special reference to internal fixation. | Fracture healing is a repair process of a mechanical discontinuity loss of force transmission, and pathological mobility of bone. Through a sequence of changes of tissue development and geometry, the original structural integrity is restored. The recovery of rigidity and strength is related to tissue differentiation. I... | 376,198 | [
-0.2380981,
0.07705767,
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0.1266703,
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0.30209,
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0.1219517,
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-0.009831972,
0.07455204,
-0.1808565,
-0.2531235,
... |
[Organ tolerance and incomplete bone marrow chimera in dogs]. | Cyclophosphamide-induced chimeras develop organ tolerance as do radiation chimeras, as long as hemopoietic cells of donor origin are detectable, independent of the degree of chimerism (n = 7). 4 of 7 dogs with reversion of chimerism rejected their kidney grafts within 11 to 29 days. Three of them, however, retained the... | 376,244 | [
-0.0466036,
0.05915014,
0.1071802,
0.00529512,
0.3080248,
-0.2360225,
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0.0008130861,
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0.1089078,
-0.1287983,
0.05520127,
0.08132251,
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0.1500469,
0.2347471,
-0.07240798,
0.07083768,
0.005340835,
0.073380... |
Topical anesthesia in preendoscopic medication: spray versus lozenges. | Patients' acceptance of upper fiberpanendoscopy was significantly (p less than 0.001) better when topical anesthesia with oxybuprocaine was performed with a spray than with a lozenge. | 376,306 | [
0.2443108,
0.005418436,
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0.09396677,
0.1237333,
-0.1150893,
0.2771912,
0.4255638,
0.01475535,
... |
Post-transplantation ureteral stricture: controlateral pyelocalicostomy. | An extensive ureteral stricture developed in a patient 10 years after a renal transplantation. A normal controlateral collecting system has been used for a pyelocalicostomy with excellent postoperative result. | 376,315 | [
0.03789819,
0.007237901,
-0.355137,
-0.1346913,
0.1142586,
-0.2971776,
-0.05278953,
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0.06895866,
0.08621101,
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0.08552271,
0.04363773,
-0.1787549,
-0.4267469,
0.2839001,
0.2979779,
-0.08561634,... |
Proteolytic enzymes in the Rhodnius prolixus midgut. | Sequential chromatographic fractionation of Rhodnius prolixus midgut homogenate yielded only one endopeptidase, but revealed the presence of carboxypeptidase-A and B-like enzyme, di- and tripeptidases, as well as aminopeptidase activities. | 376,330 | [
-0.1422296,
-0.3942753,
-0.2435122,
0.1215897,
0.09783696,
-0.3450552,
-0.2527273,
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0.2695054,
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-0.588812,
-0.02177367,
0.06945651,
-0.02452149,
0.08568307,
0.1939643,
-0.04936... |
Protective effects of supplemental vitamin E against infection. | Vitamin E supplementation (dl-alpha-tocopheryl acetate except where noted) in excess of requirement significantly increased humoral immune response or disease resistance. Mice immunized with sheep red blood cells or tetanus toxoid and fed the supplemental vitamin demonstrated increased plaque-forming cells (PFC) and he... | 376,353 | [
-0.4005423,
-0.2404744,
-0.1578263,
-0.1884182,
0.2612449,
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0.3463921,
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0.2205792,
0.07781383,
0.5414141,
0.2835266,
0.1564825,
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0.04873028,
-0.160588,
0.5824848,
0.2844416,
-0.07045553,
0.06364488,
-0.06... |
Chlamydial serology in infertile women by immunofluorescence. | The chlamydial serum immunoglobulin G antibodies of 128 infertile women were determined by a single-antigen (L2) immunofluorescence test. The antibody titers were compared with those of female contacts of men with nonspecific urethritis and with those of "normal" pregnant women. Among infertile women, 43% lacked chlamy... | 376,359 | [
0.3431421,
-0.2592848,
0.05058624,
0.1230682,
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-0.3183013,
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0.1010524,
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0.09498891,
0.2518923,
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0.08637832,
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-0.5332673,
0.1112728,
-0.2984329,
-0.1528877,
-0.05636532,
0.2919402,
-0.1534936... |
Cimetidine in anastomotic ulceration after partial gastrectomy. | In order to assess the efficacy of cimetidine in patients with endoscopically anastomotic ulcer after partial gastrectomy, 21 such patients entered a double-blind prospective clinical trial. At endoscopy after 4 wk of treatment, 8 of 12 patients treated with 1 g of cimetidine daily compared with 1 of 9 patients who rec... | 376,390 | [
0.0492536,
-0.04043746,
-0.2776282,
-0.4609099,
0.03929038,
-0.06784214,
0.08733918,
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0.3537412,
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0.1545679,
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0.02978841,
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0.1848765,
-0.08844789,
0.2514671,
0.1121505,
0.1509144,
0.056797... |
Relationship between membrane-bound immunoglobulin and viral antigens in liver cells from patients with hepatitis B virus infection. | In an attempt to define further the significance of immunoglobulin G (IgG) fixed in vivo to the hepatocyte membrane in hepatitis B virus (HBV) infection, we have studied the relationship between presence of membrane-bound IgG and that of intracellular hepatitis B surface (HBsAg) and core (HBcAg) antigens in hepatocytes... | 376,391 | [
0.1113039,
-0.1198857,
-0.2127742,
0.2155841,
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0.06889228,
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0.07137243,
0.2802834,
0.08813522,
0.08521988,
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-0.3084841,
0.1476915,
0.127252,
0.05996127,
-0.09105635,
... |
Functional interactions beween the DNA ligase of Escherichia coli and components of the DNA metabolic apparatus of T4 bacteriophage. | T4 phage completely defective in both gene 30 (DNA ligase) and the rII gene (function unknown) require at least normal levels of host-derived DNA ligase (E. coli lig gene) for growth. Viable E. coli mutant strains that harbor less than 5% of the wild-type level of bacterial ligase do not support growth of T4 doubly def... | 376,399 | [
0.1187855,
0.2273145,
-0.1285311,
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0.1770168,
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0.04327408,
0.1962672,
0.09192053,
0.1080804,
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0.06676473,
0.04243393,
0.2336025,
-0.09065425,
-0.... |
Mapping of restriction sites in the argF gene of Escherichia coli by partial endonuclease digestion of end-labeled DNA. | A detailed physical map depicting the cleavage sites generated by ten different restriction endonucleases was prepared for the argF region of the Escherichia coli K-12 genome carried on a 1650 base pair fragment capable of directing the in vitro synthesis of ornithine transcarbamylase (OTCase; ec 2.1.3.3) under the con... | 376,404 | [
-0.09566882,
0.07835615,
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0.0425865,
-0.344882,
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-0.372194,
0.1194152,
0.1140805,
0.004993638,
0.0110596,
0.1594181,
0.1362209,
0.302976,
-0.8586438,
0.3125271,
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-0.04797611,
0.2290638,
-0.07065545,
0.6046403,
0.3360103,
-0.4019534,
0.15... |
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