title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Comparison of oral sucrose and glucose electrolyte solutions in the out-patient management of acute gastroenteritis in infancy. | Seventy-three children under the age of 18 months presenting with acute gastroenteritis were given an electrolyte mixture with added sucrose or glucose in a randomized double-blind trial. The time taken to recovery in those sucessfully treated as out-patients was identical. However, of the 34 who received glucose, 11 (... | 368,231 | [
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The in vitro suppression of spontaneous erythrocyte autoimmune responses with lymphocytes activated with concanavalin A. | When normal mouse spleen cells are cultured in vitro, large numbers of cells develop that produce antibody toward antigens found on bromelain-treated mouse erythrocytes (BrMRBC). The in vitro culture also generates T cells that mediate DTH toward these antigens. We have suggested that under in vivo conditions, suppress... | 368,237 | [
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Immunological properties of hyaluronidases associated with temperate bacteriophages of group A streptococci. | The antigenic relationships of hyaluronidases, bound and free, associated with temperate bacteriophages of group A streptococci were examined with antibody against purified whole phage and with antibody against phage-bound enzyme released by urea and purified to homogeneity. Studies performed by double diffusion in aga... | 368,286 | [
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Extracellular cytolysis by activated macrophages and granulocytes. I. Pharmacologic triggering of effector cells and the release of hydrogen peroxide. | Lymphoma cells were rapidly lysed by activated macrophages and granulocytes in the presence of PMA. Release of 51Cr from lymphoma cells correlated closely with their destruction as viewed by scanning electron microscopy, and with reduction in the number of trypan blue-excluding cells. The standard assay involved 51 Cr ... | 368,287 | [
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Comparison of light-microscopic methods for visualizing horseradish peroxidase granules in stained and unstained tissue. | This study was directed toward a comparison of the effectiveness of three different light-microscopical methods for identifying and studying the features of cells that contain horseradish peroxidase (HRP) granules. The cells studied were located in the trigeminal ganglia and were labeled after the injection of HRP solu... | 368,347 | [
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Foreign body perforation of the esophagus initiating traumatic pericarditis in an Australian fur seal. | Postmortem examination of a juvenile Australian fur seal, Arctocephalus pusillus doriferus, washed ashore on Philip Island, Victoria, revealed traumatic fibrinous pericarditis and hemothorax. A foreign body lodged in the right ventricle was identified as the barbed spine of the ray Urolophus paucimaculatus. A small pun... | 368,351 | [
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Hypertension following renal transplantation. Causative factors and therapeutic implications. | During a five-year period, we studied 21 of 319 renal transplant recipients who were admitted for evaluation of refractory hypertension. For comparison we examined 93 consecutive patients in the renal transplant clinic. Hypertension, which was noted in 47% of the outpatients, occurred with greater frequency following r... | 368,359 | [
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Maternal positions for childbirth: a historical review of nursing care practices. | The basis of maternity care practices related to maternal position for childbirth is analyzed historically in a review of the American periodical nursing literature from the early 1900's to the present and of contemporary maternity nursing texts. The factors of 1) concomitant obstetrical practices, 2) the prerogative o... | 368,407 | [
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Immunohistologic demonstration of hepatitis B viral antigens in liver with reference to its significance in liver injury. | Indirect immunoperoxidase stainings for hepatitis B core and surface antigens (HBc&s Ag) were applied to formalin-fixed paraffin sections in 113 liver specimens from 56 patients. Many cytomorphologic staining characteristics of HBc&s Ag were illustrated, and the percentages of the cellular population positive f... | 368,433 | [
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[A new method of endonasal postoperative care (author's transl)]. | Aerosol therapy was tested in 27 patients postoperatively instead of nasal packing. The advantage of early ventilation and drainage prevents secondary infections. The constant decongestion embolishes band-formation. | 368,470 | [
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The cytoskeleton in cultured cells: coordinate in vitro regulation of cell growth and shape. | Adenopolyposis of the colon and rectum (ACR) links the well-characterized phenomena of murine oncogenic virus transformation with the progression of a human cancer. The same syndrome links defects in fibroblast growth control and cytoskeletal organization to a tumor of epithelial origin. Since skin fibroblasts are invo... | 368,517 | [
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Studies with prazosin--a new effective hypotensive agent. III. An acute double-blind cross-over study comparing the effects of single doses of prazosin and hydrallazine in combination with propranolol and a diuretic. | The duration of action of a single dose of prazosin and hydrallazine on blood pressure and heart rate was studied in 16 hypertensive patients whose blood pressure was not adequately controlled by a combination of a thiazide diuretic and a beta-adrenergic blocking agent, and had required the addition of either prazosin ... | 368,538 | [
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[Role of the lysine residues in the phenylalanyl-tRNA synthetase substrates interaction]. | The effect of 2,4-pentandione on the activity of phenylalanyl-tRNA synthetase (Phe-RSase) from E. coli MRE-600 was investigated. It was shown that modification of Phe-RSase with 2,4-pentandione leads to decrease of the aminoacylation rate without an influence on the ATP--[32P]pyrophosphate exchange reaction rate. tRNAP... | 368,601 | [
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In vitro breakage of plasmid DNA by mutagens and pesticides. | Covalently closed circular molecules of the colicinogenic plasmid E1 can serve as sensitive indicators for detecting in vitro breakage of DNA. After these molecules are radioactively labeled and purified by cesium chloride density-gradient centrifugation, they are incubated with the compounds to be tested. Samples are ... | 368,611 | [
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The E. coli gene encoding heat stable toxin is a bacterial transposon flanked by inverted repeats of IS1. | Restriction endonuclease subclones of the Escherichia coli gene encoding the heat stable (ST) toxin exhibit a stem and loop structure similar to those seen in many procaryotic transposons. An EcoRI DNA fragment encoding tetracycline (Tc) resistance but no transposition functions was spliced into the ST gene in one of t... | 368,646 | [
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Escherichia coli mutants accumulating the precursor of a secreted protein in the cytoplasm. | The maltose binding protein of Escherichia coli is secreted into the external periplasmic compartment of the cell. This article describes a selection procedure for the isolation of mutants which fail to export this protein. These mutants probably result from alterations in the amino terminal 'signal sequence', causing ... | 368,649 | [
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[Computer-assisted 201Tl myocardial scintigraphy in the routine diagnosis of coronary heart disease (author's transl)]. | The aim of the study was to evaluate the validity of 201Tl scanning for clinical routine use in the diagnosis of coronary heart disease. A computer-aided matrix with very high resolution displaying subtle color nuances was used. For semi-quantitative assessment a scale with 16 colors was applied. This permitted to diff... | 368,719 | [
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Androgen trial in renal anaemia. | A double blind cross-over trial of Nandrolone decanoate (Decadurabolin) was carried out in 27 patients with anaemia due to end stage renal disease, stabilised on regular haemodialysis. Sixteen patients completed the study, the other patients being excluded from the final analysis for a variety of reasons including side... | 368,770 | [
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An Escherichia coli mutant with an amino acid alteration within the signal sequence of outer membrane prolipoprotein. | Lipoprotein has been purified from an Escherichia coli strain carrying a mutation in the structural gene for murein lipoprotein (mlpA). Amino acid analysis of the purified mutant lipoprotein indicates that the mutant lipoprotein corresponds to the uncleaved prolipoprotein with a single amino acid replacement of glycine... | 368,803 | [
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Computer-aided classification and assessment of patients in multicenter trials. | The automated diagnostic procedure appears to be particularly suitable for clinical psychopharmacological trials since it provides a diagnostic definition and a psychopathological profile of patients assessed by various investigators of different centers where a different kind of psychopathology as well as different cu... | 368,818 | [
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[Errors of the placebo test]. | The difficulties inherent in clinical experimentation in phlebology, stem from the fact that they concern highly subjective functional problems, and are thus difficult to measure. The answer to these difficulties seems to be found in the use of the double blind method. This method, however, contains numerous causes of ... | 368,823 | [
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One-stage repair of a cervical esophagostome with two myocutaneous flaps from the neck and shoulder. | A large esophagostome in a heavily radiated neck was reconstructed in one stage, using a sternocleidomastoid myocutaneous flap for lining and a trapezius myocutaneous flap for covering. The patient began eating on the seventh day and was discharged on the tenth day following the repair. Barium swallow studies demonstra... | 368,843 | [
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Reconstruction of the oral mucocutaneous junction. | An inset free skin graft from the postauricular area was used to create a natural appearing "white roll" mucocutaneous junction in a lip repair. | 368,844 | [
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Muscle activity during chest wall restriction and positive pressure breathing in man. | The effects of sustained constriction of the rib cage (RCC), constriction of the abdomen (AC) and of breathing against a positive pressure of 10 cms of water (PPB) were studied in four normal subjects with moderate constant hypercapnia. Intercostal electrical activity (Eic) was measured by implanted wire electrodes and... | 368,929 | [
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[Antimicrobial properties of extracts from Rhizophora mangle L]. | Aqueous and alcoholic extracts are obtained from the roots, leaves and stems of ruddy mangrove-tree (Rhizophora mangle L.), a very common plant in Cuban coasts and to which different curative properties are attributed in our popular medicine. The inhibitory activity of these extracts on the growth of different human pa... | 368,923 | [
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Immunoelectrophoretic studies on human small intestinal brush border proteins. A qualitative study of the protein composition. | The human small intestinal brush border proteins were studied qualitatively by crossed immunoelectrophoresis. Brush border membranes were purified from human jejunum and the proteins released by Triton X-100. Rabbits were immunized with the released proteins and by using a double layer immunofluorescence technique the ... | 368,959 | [
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[Clinical and microbiological studies on the effect of locally applied aminofluorides on bacterial plaque and gingiva condition of Soviet school children]. | In a short-term (over 4 weeks) clinico-microbiological study on 18 Soviet school children, 12 years of age, it was found that a supervised oral hygiene action with the amine fluoride-containing caries-preventing agents Silca and Elmex fluid (produced in the GDR) had resulted in a marked reduction in plaque formation, a... | 369,049 | [
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A computer-assisted filing system for urologic information. | Our increasingly inefficient, cumbersome, often ineffective and time-consuming manual mental cataloguing and retrieving system indicated to us that there must be a better technique available. However, our search of existing systems failed to reveal any matching our needs. Therefore, we developed a 4-category system for... | 369,093 | [
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0.03295224,
-0.4374927,
0.36... |
[Reconstructive-restorative operations of the skin after amputation of the limbs]. | Up to 70% of cases admitted for primary prosthetics after amputation of the extremities suffer from some defects aod diseases of the stumps requiring surgical treatment. The experience of the Leningrad Scientific Research Institute of Prosthetics with 593 reconstructive-restorative operations on the stumps of the extre... | 369,102 | [
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[Methods and value of an immunofluorescence-optical determination of IgM, IgG and IgA rheumatoid factors]. | Today the immuno-fluorescence technique is the simplest method to detect rheumatoid factors of all immuno-globulin classes. When applying sheep erythrocytes, standard sera may be used without exception. The airdried smear of the cells is to be incubated with rabbit anti-human-erythrocyte serum. The rheumatoid factors o... | 369,226 | [
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[Modern concept of the makeup of intestinal microflora in healthy adults]. | Analysis of the literature data on the significance of normal intestinal microbial population in the vital activity of the organism, and also on the sequelae of unfavourable shifts in the intestinal microecology is presented. The results of personal studies on the composition of normal microbial population in healthy a... | 369,243 | [
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The general pharmacology of prostacyclin PGI2, (PGX): a new prostaglandin especially active on the cardivascular system. | Prostacyclin is a new prostaglandin first demonstrated as a product of arterial microsomes and prostaglandin endoperoxide intermediates. The potential to form prostacyclin has now been demonstrated in many organs. It inhibits platelet aggregation, inhibits gastric acid secretion, stimulates the monkey but not the rat u... | 369,253 | [
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... |
Respiratory and circulatory responses to sustained positive-pressure breathing and exercise in man. | To investigate the effects of sustained positive-pressure breathing (PPB) on the adaptation of respiratory and circulatory functions to exercise, 8 healthy volunteers were exposed to PPB of air at 15 and 30 cm H2O in the supine position at rest and while performing leg exercise at 50% of individual maximal working capa... | 369,297 | [
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0.1860... |
Prevention of bacterial infections of mucosal surfaces by immune secretory IgA. | 1) Colonization and diarrhea in the rabbit due to RDEC-1 strain E. coli elicits an immune response that prevents subsequent infection with the same bacterium. 2) RDEC-1 and InvEC strain colonization of the gut of pregnant rabbits is followed by the appearance, post-delivery, of anti-InvEC or RDEC-1 strain s-IgA in the ... | 369,313 | [
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0.2576561,
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Epidemiology of Guillain-Barré syndrome. | The only measures of morbidity for Guillain-Barré syndrome in well-defined populations in the continental United States come from Olmsted County, Minnesota, and San Joaquin County, California. The estimated incidence rates are between 1 and 2 cases per 100,000 population per year. Despite the hazards of generalizing fr... | 369,322 | [
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Empiric therapy of febrile granulocytopenic patients. | Antibiotic therapy in granulocytopenic cancer patients, the risk factors predisposing these patients to infection, and the signs, symptoms and types of infections occurring in these patients are reviewed. The four most commonly isolated organism at most cancer treatment centers are Escherichia coli, Klebsiella spp., Ps... | 369,364 | [
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Group B streptococcal colonization and antibody status in lower socioeconomic parturient women. | This investigation was undertaken to determine the prevalence of group B streptococcal vaginal and throat colonization among lower socioeconomic pregnant women and the antibody concentration to the capsular polysaccharide antigen of type III group B streptococcus in their sera. Group B streptococci were recovered from ... | 369,376 | [
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Treatments of premature ejaculation and psychogenic impotence: a critical review of the literature. | Research on the treatments of premature ejaculation and psychogenic impotence is reviewed. Problems with the existing definitions of these disorders are discussed. The studies are reviewed under seven major headings: depth therapies, behavior therapies, hypnosis, drug therapy, mechanotherapy, reeducative and supportive... | 369,478 | [
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HLA antigens in ocular cicatricial pemphigoid. | HLA antigen frequencies were studied in 45 patients with ocular cicatricial pemphigoid. HLA-B12 was found to have an increased frequency of 44.4% in patients with ocular cicatricial pemphigoid, which was statistically significant when compared with a frequency of 19.6% in the control population (P less than .001 or P l... | 369,492 | [
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... |
Magnetodontics. The use of magnetic forces in dentistry. | A recently discovered alloy of cobalt and samarium (CO5Sm) has exceptional magnetic properties. A laboratory evaluation was made of the grip force of samples of this alloy of a size suitable for dental use. A review of both dental and general literature points to the need for establishing, prior to widespread usage, th... | 369,500 | [
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Serological response to intracaecal injections of antigenic mouse tumour cells. | Immunofluorescence studies of sera from mice with induced enhancement of tumour growth demonstrated that these sera contained factors ("interfering factors") which in an apparently competitive manner interfered with the subsequent binding of specific antibodies to antigenic sites on the tumour-cell membrane. The factor... | 369,587 | [
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An essential arginyl residue in yeast hexokinase. | The inactivation of yeast hexokinase A (ATP:D-hexose 6-phosphotransferase, EC 2.7.1.1) by phenylglyoxal obeys pseudo first-order kinetics. Formation of a reversible enzyme-reagent complex prior to modification is suggested by the observed saturation kinetics. Loss of activity correlates with the incorporation of 1 mol ... | 369,611 | [
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Regulation of glucosamine-6-phosphate deaminase synthesis in yeast. | A basal level of glucosamine-6-phosphate deaminase is detected in yeast cells grown on glucose. However, a burst of enzyme production occurs in the presence of N-acetylglucosamine in pathogenic Candida albicans and non-pathogenic Saccharomyces cervisiae. The enzyme synthesis stops and its concentration in the cells dec... | 369,615 | [
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[T- and B-lymphocytes in patients with chronic renal failure and in recipients of cadaveric allokidneys during the immediate posttransplant period]. | Investigations of the thymus-dependent and thymus-independent lymphocytes populations of patients with chronic renal failure showed the activity of the T-lymphocytes system to be depressed in these cases. Both the lymphocyte populations took part in the rejection, but the degree of their participation differed. There w... | 369,635 | [
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The stripping of varicose veins: a clinical trial of intermittent compression dressings. | This study compares a standard method of care for patients following excision and ligation of varicose veins with a new regimen which involves intermittent compression dressings. In a fully randomized between-patient prospective trial it has been found that the use of such dressings results in a significant reduction i... | 369,643 | [
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Improved metabolic profiles in insulin-treated diabetic patients given an alpha-glucosidehydrolase inhibitor. | An alpha-glucosidehydrolase inhibitor (acarbose; BAY g 5421) taken with food was compared with dummy tablets in seven insulin-treated diabetic patients over eight-hour periods that included breakfast, lunch, and two snacks. Acarbose diminished the postprandial increases in blood glucose, lactate, and pyruvate concentra... | 369,651 | [
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Comparison of natriuretic, uricosuric, and antihypertensive properties of tienilic acid, bendrofluazide, and spironolactone. | The antihypertensive properties of the new diuretic tienilic acid were investigated. Thirteen previously untreated hypertensive patients took part in a double-blind crossover study in which 30 days' treatment with tienilic acid 250 mg, bendrofluazide 5 mg, and spironolactone 100 mg were compared. Bendrofluazide caused ... | 369,652 | [
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A corneal model for studying the interaction between the endothelium and sensitized lymphocytes. | We wished to develop a simple model for morphological studies on the interaction between the corneal endothelium and specifically sensitized lymphocytes. Rabbits were transplanted with orthotopic allogeneic skin or corneal grafts. After the onset of the transplantation reaction, lymphoid cells from the recipient's sple... | 369,666 | [
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Phase II study of ICRF-159 in refractory metastatic breast cancer. | ICRF-159, at a dose of 300 mg/m2, was given orally every 8 hours for nine doses every 21 days to 40 patients with metastatic breast cancer refractory to hormonal therapy and cyclophosphamide, methotrexate, 5-fluorouracil, and adriamycin chemotherapy. Two patients with soft tissue disease had short-lived partial respons... | 369,681 | [
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Antibodies against chromosomal HMG proteins stain the cytoplasm of mammalian cells. | Antibodies specific to protein HMG-1 were purified by affinity chromatography on Sepharose columns to which HMG-1 was covalently bound. Immunofluorescence studies with these antibodies reveal that HMG-1 or components which immunologically cross-react with HMG-1 are present in the cytoplasm of Chinese hamster V-79, rat ... | 369,705 | [
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Phorbol myristate acetate: effect of a tumor promoter on insulin release from isolated rat islets of Langerhans. | Phorbol myristate acetate (PMA), a tumor-promoter capable of influencing biologic functions of many cell systems, has been demonstrated to augment glucose-initiated insulin release from isolated rat islets of Langerhans. PMA caused a 2-fold increase in insulin release. This effect of PMA did not alter the sigmoidal rel... | 369,826 | [
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Changes in plasma luteinizing hormone-releasing hormone and gonadotropin concentrations during constant rate intravenous infusion of luteinizing hormone-releasing hormone in cyclic rats. | Further analysis has been made of the response of the rat pituitary gland to LHRH during the 4-day estrous cycle. LHRH was infused iv at a constant rate (50 ng/h) into phenobarbital-treated rats at different times during the estrous cycle. Infusion at this rate in proestrous rats simulates the rising and plateau phases... | 369,828 | [
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Further studies on the role of calcium in glucocorticoid-induced lymphocytolysis. | In a previous study comparing the effects of triamcinolone acetonide (TA) and a divalent cation ionophore (A23187) on rat thymocytes, we proposed an important contributory role for Ca2+ in glucocorticoid-induced cytolysis. The plausibility of this hypothesis was tested further in thymic lymphocytes (thymocytes) and lym... | 369,844 | [
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0.4374847,
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32P-labeling patterns in rat pancreatic islets: tissue source of the radiophosphate released after glucose stimulation. | Immediately after stimulation with glucose in vitro, isolated rat pancreatic islets prelabeled with [32P]orthophosphate release a pulse of [32P]orthophosphate into the media (the "phosphate flush"). Islets have been rapidly frozen before, during, and after this pulse to assess the concurrent changes in the distribution... | 369,845 | [
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Effect of acetylsalicylate on surgical bleeding, postoperative mortality and allograft survival in rats undergoing heart transplantation. | 18 rats were treated with L-ASA before heart transplantation and daily thereafter until death or rejection. 22 animals acted as controls. A significantly higher post-operative mortality rate, without any significant modification of the transplant survival time, was found in L-ASA-treated group. | 369,874 | [
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Effect of suppression of endocrine or exocrine pancreatic function in hemorrhagic shock. | Somatostatin did not influence the pathologic consequences of hemorrhagic shock, but pancreatic duct ligation prevented the post-oligemic decline of arterial pressure and formation of toxic factors. These results indicate that pancreatic acinar cells release myocardial depressant factor and are important in the pathoph... | 369,876 | [
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0.08466182,
0.04743551,
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-0.1452593,
-0.4256557,
0.1117283,
0.2679136,
0.07417975,
0.150937,
0.2431687,
0.03735935,
-0.07824974,
-0.02646577... |
[S-Acyl derivatives of thiosalicylamides having antifungal activity. II]. | Some S-acyl derivatives of N-alkylthiosalicylamides [Table I: substances (I leads to XXXI)] were prepared and tested for antifungal activity. The substances, most of which had not been previously reported, were prepared by condensation of 2-mercapto-N-alkylbenzamides with suitable acylating agents. The antifungal activ... | 369,885 | [
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0.2660729,
0.4223114,
0.06376423,
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0.22738... |
A comparison of indoprofen and indomethacin in the supportive treatment of soft-tissue injuries in football players: a pilot study. | Twenty-four professional footballers suffering from recent soft-tissue injuries were included in a double-blind pilot trial comparing the efficacy and tolerability of indoprofen 800 mg/day and indomethacin 80 mg/day. Twelve subjects were allocated at random to each of the two drugs. Mean reduction of pain and swelling ... | 369,924 | [
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0.01127879,
0.03409241,
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0.4483612,
-0.0582631,
0.01465131,
-0.2698704,... |
Insulin administration in the frog Rana tigrina: studies on the blood glucose and the histology of the endocrine pancreas. | The effect of various doses of insulin (25-, 50-, and 150 U/kg body weight) on the blood glucose level and islet-cytology of the frog Rana tigrina was studied until 96 h. Following the hormonal administration the frogs exhibited hypoglycemia, abnormal neuromuscular activity and degranulation of both the insulin secreti... | 369,939 | [
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0.05453303,
0.2489858,
0.2222567,
0.02794538,
-0... |
[Regulation of the activity of Escherichia coli deo-operon structural genes: the mutation mapped within the operon boundaries and affecting drm and pup gene activity]. | The mutant AIR38 is isolated from Escherichia coli K-12 strain deficient in thymidilate synthetase and deoxyriboaldolase (HfrH, thy, dra)--by selection for low thymine requirement on the medium containing inosine as the carbon source. Under the conditions mentioned the mutant AIR38 (thy, dra) grows at low thymine conce... | 369,945 | [
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0.06539587,
-0.0039074,
0.4345545,
0.3632937,
-0.4939408... |
Isolation of IgE from normal mouse serum. | Mouse IgE was isolated from reaginic ascitic fluid and an antiserum to it was produced in rabbits. An immunoadsorbent, prepared with this antiserum, was used to isolate IgE from normal mouse serum. Mouse serum proteins, isolated by (NH4)2SO4 (40--60%) precipitation, were applied to the anti-IgE immunoadsorbent and elu... | 369,992 | [
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0.3938554,
0.06732899,
0.1604402,
-0.07107688,
0.1... |
Cultivation of Ureaplasma urealyticum in continuous culture. | Continuous culture of Ureaplasma urealyticum is reported with a steady-state cell biomass of greater than 10(6) cells per ml. Thus, large cell numbers can be easily obtained; in addition, the system provides a powerful means for exploring what nutrients(s) limits the growth yield of this organism. Urea is shown not to ... | 370,008 | [
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0.4661825,
0.2048301,
0.05393444,
0... |
Relationship between enterotoxin production and serotype in enterotoxigenic Escherichia coli. | We examined the relationship between serotype and enterotoxin production in 109 enterotoxigenic Escherichia coli strains isolated from 109 patients with severe cholera-like diarrhea in Dacca, Bangladesh. Of 69 strains producing both heat-labile and heat-stable toxins, 59 (86%) belonged to the one of four O serogroups, ... | 370,013 | [
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0.4445228,
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0.3262802,
0.4319357,
-0.292912,... |
Capacity of virulent Treponema pallidum (Nichols) for deoxyribonucleic acid synthesis. | Treponema pallidum (Nichols) was extracted from infected rabbit tissue, and cell lysates were prepared for monitoring thymidine kinase and deoxyribonucleic acid polymerase activities. No thymidine kinase could be demonstrated in preparations of T. pallidum or the cultivable T. phagedenis biotype Reiter. Significant lev... | 370,016 | [
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0.1640879,
0.1733263,
0.4591592,
0.08138105,
-0.2005... |
Characteristics of lipid A-protein complex from endotoxin of Shigella dysenteriae type 1 (S and R strains). | Mild acetic acid hydrolysis of endotoxin (lipopolysaccharide-protein complex) of Shigella dysenteriae type 1 (S and R forms) yielded a lipid A-protein complex that consisted of amino acids, fatty acids, and sugar and, in terms of chemical composition, displayed no marked differences between the S and R forms. Its prote... | 370,018 | [
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0.03930194,
0.2606121,
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0.2020092,
0.06036664,
0.07168... |
Influence of carbonyl iron treatment on lymphocyte subpopulations. | The influence of carbonyl iron treatment on different human mononuclear cell subsets was investigated. There is evidence that, in addition to removal of phagocytic cells, lymphocytes are depleted, B cells being more affected than other subpopulations. | 370,025 | [
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0.1692727,
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0.1035329,
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0.08617186,
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0.4163153,
0.1016255,
0.440401,
-0.06179721... |
Model-fitting approaches to the analysis of human behaviour. | Model-fitting methods are now prominent in the analysis of human behavioural variation. Various ways of specifying models have been proposed. These are identical in their simplest form but differ in the emphasis given to more subtle sources of variation. The biometrical genetical approach allows flexibility in the spec... | 370,072 | [
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0.3095403,
0.26668,
0.07543672,
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... |
Effect of growth medium on the relative polypeptide composition of cellular outer membrane and released outer membrane material in Escherichia coli. | When ratios of the major polypeptides of the outer membrane isolated from cells of Escherichia coli B grown in minimal medium containing either a single amino acid or several amino acids were compared, no difference was observed. However, the ratio of these polypeptides in outer membrane material released into the medi... | 370,090 | [
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0.1213836,
0.5067474,
0.1283927,
-0.01487694,
... |
Regulation of N-acetylglutamate synthesis in Salmonella typhimurium. | N-Acetylglutamate synthase was purified to homogeneity from Salmonella typhimurium. The enzyme is subject to repression and feedback inhibition by arginine. Inhibition studies indicated that arginine exerts its effect primarily by reducing the affinity of the enzyme for glutamate. | 370,091 | [
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0.06064012,
0.2216792,
0.004107095,
-0.... |
Synthesis of ribosomal proteins during the cell cycle of the yeast Saccharomyces cerevisiae. | Centrifugal elutriation was used to separate yeast cells by their cell cycle position. The rate of synthesis of ribosomal proteins showed a constant exponential increase through the cell cycle. | 370,092 | [
-0.006293063,
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0.1177722,
0.08240062,
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0.2707212,
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0.5585742,
0.2260309,
-0.05449468,
... |
Amber suppressor mutations in Pseudomonas acidovorans. | Almost 50% of the clones of Pseudomonas acidovorans(pLM2) selected for resistance to tetracycline supported the growth of an amber mutant of bacteriophage PRD1. | 370,094 | [
0.178336,
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0.06207956,
0.5329826,
-0.02443795,
0.2028978,
0.006263072,
-0.15932... |
The relA locus specifies a positive effector in branched-chain amino acid transport regulation. | The regulation of branched-chain amino acid transport and periplasmic binding proteins was studied in Escherichia coli strains which were isogenic except for the relA locus, the gene for the "stringent factor," which is responsible for guanosine tetraphosphate synthesis. The strain containing the relA mutation could no... | 370,095 | [
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0.1178012,
-0.05627311,
0.5582998,
0.2592381,
0.20382... |
Acetohydroxy acid synthase I of Escherichia coli: purification and properties. | Several properties of the three acetohydroxy acid synthases of Escherichia coli have been compared in crude extracts. The three enzymes can be readily distinguished from each other. Acetohydroxy acid synthase I, the product of the ilvB gene, has been purified to near homogeneity. The purification was made possible by t... | 370,104 | [
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0.1150108,
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0.2713303,
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0.6310896,
0.2688749,
0.4344566,
-0.3469635,
... |
Cell differentiation during fruiting body formation in polysphondylium pallidum. | The spatial pattern of cellular differentiation was studied during fruiting body formation in Polysphondylium pallidum using 3 different staining methods: Calcofluor fluorescence (cellulose accumulation), neutral red (prestalk cells) and immunofluorescence (prespore cells). Neutral-red staining revealed the existence o... | 370,128 | [
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0.3138388,
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0.1999933,
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0.2036351,
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0.3344203,
0.5632918,
0.4924721,
-0.01846704... |
Electron microscopy of spermatocytes previously studied in life: methods and some observations on micromanipulated chromosomes. | A new method is offered for combined living cell and electron-microscopic studies of spermatocytes (or other cells) which normally do not adhere to glass. The key step is micro-injection of glutaraldehyde near the target cell whenever desired during observation in life. Fixation begins and simultaneously the cell is st... | 370,131 | [
0.1478064,
0.2079882,
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0.0295073,
0.0316293,
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0.1151505,
0.3779813,
0.1523505,
-0.02083363,
... |
Metabolically deficient dwarf-colony mutants of Escherichia coli: deficiency and resistance to antibiotics of strains isolated from urine culture. | Sixteen metabolically deficient dwarf-colony mutants of Escherichia coli were isolated from urine culture and represented about 2% of all E. coli isolated during the same period. In 14 cases, mutants were isolated from debilitated patients: elderly persons or patients in the terminal stages of a chronic disease. In 15 ... | 370,140 | [
0.09718786,
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-0.06210814,
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0.8499944,
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0.09805388,
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0.07972328,
0.04103752,
0.1799028,
-0.05928601,
... |
Esterase activity in Candida species. | The purpose of this investigation was to ascertain the lipolytic activities (specifically, esterase) of those species of Candida that are most commonly isolated from human infections. Eight species of Candida were surveyed for their ability to hydrolyze various polyoxyethylene sorbitan compounds (Tweens). Of the 64 iso... | 370,150 | [
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0.08410262,
-0.07771198,
-0.06999414,
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0.1105827,
0.09612708,
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0.1312626,
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0.02507995,
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-0.4266371,
0.261638,
0.2108995,
0.378306,
0.2710407,
0.3831779,
0.0154256... |
Acute hemodynamic effects of tocainide in patients undergoing cardiac catheterization. | To characterize the acute hemodynamic effects of tocainide hydrochloride, a new antiarrhythmic agent, 11 patients undergoing diagnostic cardiac catheterization were given intravenous infusions of the drug for 15 minutes at rates of 0.50 (six patients) or 0.75 (five patients) mg/kg/min. The hemodynamic status of these s... | 370,155 | [
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0.04575565,
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0.09741747,
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0.7286424,
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0.08414339,
-0.01375343,
0.3512274,
0.005174209,
0.1859377,
-0.29216... |
Cell contacts and sorting out in vivo: the behaviour of some embryonic tissues implanted into the developing chick wing. | The interaction of cells from embryonic liver, neural retina and mesonephros with cells from limb-bud mesenchyme has been investigated in vivo by grafting these tissues into the developing chick wing-bud. The implanted cells were in all cases from quail tissue which can be recognized histologically. As embryonic liver ... | 370,329 | [
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0.1640541,
0.4642769,
0.05988267,
0.1748691,
... |
[Calorimetric study of the effect of salicylate in man during heat exposure and exercise (author's transl)]. | 1. The effect of sodium acetylo-salicylate (2 g per os) on the thermoregulatory responses of 10 male subjects was studied by direct and indirect calorimetry during two tests : heat exposure at 37 degrees C and exercise (50 W) at 25 degrees C. Both test were performed twice : with salicylate treatment and with a placebo... | 370,367 | [
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0.1354549,
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0.06024858,
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0.01913792,
-0.3276903,
0.6355682,
0.2332735,
-0.0190985,
-0.2239936,
0... |
Personal identification using dental prostheses. | A personal identity mark may be added to a metal or an acrylic resin prosthesis. The importance of this technique, particularly in terms of forensic investigation and identification, should make it a compulsory dental procedure. Where metal is involved, engraving is the most desirable method of marking. The heat resist... | 370,370 | [
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0.4527235,
0.1215173,
0.235523,
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0.06619493,
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0.2812873,
0.1489929,
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0.3795235,
0.003342356,
-0.1744432,
0.188381,
0.0083957,
-0.04727402,
0.3545... |
Maxillary segmental osteotomies for mandibular removable partial denture patients. | The posterior maxillary osteotomy is a versatile and useful treatment alternative for a variety of dentofacial conditions. Its place in the management of bilateral distal-extension removable partial denture construction has been described along with a report of treatment of a patient. | 370,371 | [
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0.1956848,
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0.080256... |
An unusual case of lymphocele after renal transplantation. Case report. | A patient who developed a lymphocele five years after renal transplantation is presented and discussed. | 370,463 | [
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0.1329593,
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0.01980256,
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-0.1148595,
0.1426305,
0.3192413,
0.1485012,
... |
[Use of a pyrimidine-dependent mutant for effective labeling of the DNA OF Aspergillus nidulans]. | Incorporation of the radioactive label from pyrimidines into RNA and DNA of an Aspergillus nidulans pyrimidine-dependent mutant was studied. The label from [14C2]uridine was incorporated at the highest rate into both fractions of nucleic acids from A. nidulans of the wild type and pyr-mutant. The content of the label i... | 370,508 | [
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0.2786623,
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0.007504174,
-0.06836291,
-0.006271522,
-0.06275751,
0.2440969,
0.448924,
0.2026379,
-0.1696534,
... |
[Effect of cell reserve carbohydrates on an increase in the keeping qualities of baker's yeast]. | Synthesis of reserve carbohydrates (trehalose and metabolically active glycogen) can be intensified in the cells of Saccharomyces cerevisiae by adding glycerol and magnesium or phosphorus salts to the cultural broth. An increase in the content of reserve carbohydrates in the cells increases their preservation after sep... | 370,515 | [
0.05538997,
-0.1902881,
-0.1467198,
-0.09215577,
-0.04844246,
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-0.05731136,
0.1612775,
-0.01371632,
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-0.1112458,
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0.1575755,
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-0.08862614,
-0.008810014,
-0.03938607,
-0.06745367,
0.4082517,
0.6319662,
0.2284574,
-0.0... |
The effect of norharman on the metabolism of benzo[alpha]pyrene by rat-liver microsomes in vitro in relation to its enhancement of the mutagenicity of benzo[alpha]pyrene. | The effect of norharman on the metabolism of benzo[alpha]pyrene by rat-liver microsomes was studied. Separation of the metabolites into hydrophilic and hydrophobic fractions showed that norharman inhibited the conversion of hydrophobic metabolites to hydrophilic ones. Analysis of the hydrophobic metabolites by high-pre... | 370,567 | [
-0.1613748,
0.2845257,
-0.2660943,
-0.001468136,
0.2740527,
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-0.04209203,
0.2480955,
0.3260766,
0.06828661,
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0.3318162,
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0.1499599,
0.1199904,
-0.0545691,
0.1448201,
0.1469582,
0.0161655,
-... |
Mutagenicity to Salmonella typhimurium of some Aspergillus and Penicillium mycotoxins. | 17 mycotoxins produced by various Aspergillus and Penicillium species were screened for their mutagenic activity to Salmonella typhimurium strains TA98, TA100, TA1535 and TA1537, both with and without metabolic activation. Austdiol, austocystins A and D, kojic acid and viridicatumtoxin were found to be mutagenic after ... | 370,570 | [
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0.1172311,
0.3728712,
0.2349153,
0.2081168,
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-0.1975403,
0.... |
Mutagenicity tests of diflubenzuron in the micronucleus test in mice, the L5178Y mouse lymphoma forward mutation assay, and the Ames Salmonella reverse mutation test. | Diflubenzuron, one of a new class of pesticides believed to act via inhibition of chitin synthesis in the developing insect cuticle, was tested for possible mutagenic activity using the micronucleus test in mice, the L5178Y mouse lymphoma forward mutation test at the thymidine kinase locus, and the Ames Salmonella/micr... | 370,584 | [
0.04891405,
-0.2779966,
-0.076306,
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0.3607975,
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0.2877904,
-0.04704522,
0.01231201,
0.09195716,
0.192082,
0.1090478,
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0.4660011,
-0.625871,
0.09207193,
-0.0132514,
-0.0007441149,
0.07532268,
-0.2081875,
-0.0644586... |
Hypertrophic cardiomyopathy and human leukocyte antigen linkage: differentiation of two forms of hypertrophic cardiomyopathy. | To determine whether hypertrophic cardiomyopathy is associated with a human leukocyte antigen (HLA) phenotype, we tissue-typed 70 unrelated afflicted patients and 86 of their asymptomatic family members (from nine separate kindreds). Forty-five per cent of the white patients had B-12 antigen as compared to 23 per cent ... | 370,596 | [
-0.06967151,
0.1237678,
-0.1241027,
0.03642473,
-0.03570028,
-0.320277,
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0.0008804053,
0.1139578,
0.03740104,
-0.0852218,
0.2685077,
0.01522976,
0.02790806,
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-0.05610545,
0.1732185,
0.04391907,
-0.01057737,
0.4400846,
-0.3837... |
High Rates of controlled ultrafiltration combined with optimal diffusion: recent advances in hemodialysis technique. | A system which permits high rates of middle molecule removal while preserving the removal of low molecular weight substances is described. It consists of a high fluid flux hollow fiber artificial kidney and an ultrafiltration controller. When used in combination, high rates of convective transport can be achieved throu... | 370,625 | [
-0.1409973,
0.2376405,
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0.2196084,
0.1014079,
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0.2068598,
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0.04650048,
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0.2000943,
0.2843051,
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0.01227015,
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0.04128535,
-0.1954596,
-0.06024243,
0.13053,
-0.09967554,
... |
Interrelationship of time of dialysis-dependent uremia and pretransplant blood transfusions. | In a consecutive series of 167 renal allotransplants, a statistically significant correlation was found between the number of pretransplant blood transfusions and the time of dialysis-dependent uremia. This correlation suggests that one possible explanation for the association of a beneficial effect of pretransplant bl... | 370,626 | [
0.1097028,
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-0.2689525,
0.01850276,
0.2589848,
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0.1873671,
0.08672162,
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0.09373146,
-0.03647019,
0.1419918,
0.04966033,
0.024473,
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0.2498873,
0.1162385,
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0.2509451,
0.3842508,
0.3521902,
0.0381139,
0.0613... |
Effects of valproate and ethosuximide on thalamocortical excitability. | Sodium valproate and ethosuximide are anticonvulsants employed in the treatment of petit mal epilepsy; both drugs are considered to be thalamically active. Valproate and ethosuximide both decreased the average evoked response following the second of two stimuli delivered to the ventrolateral thalamus at stimulus freque... | 370,687 | [
-0.1531778,
0.1207736,
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0.2650503,
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0.4297567,
0.01179744,
0.04328353,
-0.1074494,
0.155689,
0.1440948,
... |
The interaction of RNA polymerase and lac repressor with the lac control region. | We have examined the interactions of lac repressor and RNA polymerase with the DNA of the lac control region, using a method for direct visualization of the regions of DNA protected by proteins from DNAase attack. The repressor protects the operator essentially as reported by Gilbert and Maxam (1) with some small modif... | 370,784 | [
-0.1371769,
-0.07921346,
-0.1006447,
0.1399768,
-0.04110578,
-0.1977207,
-0.4962774,
0.1989402,
0.2966958,
-0.05846886,
0.02299405,
-0.1961237,
0.1089978,
0.130683,
-0.3873805,
0.2192254,
-0.2358913,
-0.06852024,
-0.08361181,
0.02775455,
0.6658965,
-0.09015968,
-0.328945,... |
The DNA sequence at the T7 C promoter. | Restriction fragments of T7 DNA which selectively bind E. coli RNA polymerase have been identified. These include fragments located close to the beginning of gene 1 where according to Minkley and Pribnow (1973) there is a promoter called C. The smallest fragment from this region which binds RNA polymerase has been sequ... | 370,790 | [
0.2363669,
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0.06223694,
0.1788005,
-0.5378723,
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0.09665396,
0.1773686,
-0.008181899,
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0.2716545,
-0.1232458,
-0.4223081,
-0.1036097,
-0.2076162,
-0.1268463,
0.2047149,
0.0169013,
0.7328963,
-0.1731412,
-0.2272385,... |
Viral causes of psychiatric disease. | Current evidence on the role of viruses in the causation of psychiatric illness is reviewed. Herpes simplex encephalitis is relatively well defined but a wider role for this virus, particularly in relation to affective disorders, is suggested by some Scandinavian surveys of antibody titres in psychiatric populations. T... | 370,811 | [
-0.1974604,
-0.1361058,
0.06525036,
-0.234162,
0.07532953,
-0.2764944,
-0.4442864,
-0.07438378,
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0.2438972,
0.1890744,
0.01087424,
0.2748041,
0.2966476,
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0.1901568,
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0.2569047,
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0.008500068,
0.2513901,
0.04096305,
-0.1524852,
... |
The clinical evaluation of obsessionality: a development of the Leyton Obsessional Inventory. | The Leyton Obessional Inventory gives both an indication of the range of obsessional symptoms present and the degree of resistance and interference associated with each symptom. A new method is described in which the covariation of resistance and interference is represented in the form of a matrix. The results, using t... | 370,862 | [
0.04485677,
0.3231009,
0.1057778,
-0.03053953,
0.1723785,
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0.06233323,
-0.09241305,
0.0338266,
0.01169688,
-0.1307858,
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-0.402176,
0.08961003,
-0.06400215,
0.3239519,
-0.09556727,
0.04416661,
-0.09425352,
-0.1787276,
-0.0945635... |
Knowledge-based computer-assisted diagnosis of chest radiographs. | The computer can produce structured radiologic content which can potentially keep the radiologists current in radiology literature. As the radiologist continues to make observations and uses the available information, he has at his fingertips with the computer the current information to offer appropriate differential d... | 370,892 | [
-0.3080671,
0.04379995,
-0.2415763,
-0.1700411,
0.1030213,
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-0.1842486,
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0.1746592,
0.08952021,
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-0.04512377,
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-0.09846427,
0.08392699,
-0.01126404,
-0.1056634,
0.05723846,
0.2172297,
-0.2... |
Radiobiological considerations in the use of total-body irradiation for bone-marrow transplantation. | On radiobiological grounds, a therapeutic advantage should result when total body irradiation (TBI) in preparation for bone-marrow engraftment is given as a fractionated course, rather than as a single exposure at logistically reasonable dose rates. This is because cells of hemopoietic origin in general show less capac... | 370,902 | [
-0.05162308,
-0.1469758,
-0.217752,
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0.1784733,
-0.3558902,
-0.234393,
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0.02566521,
0.1254029,
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0.4047138,
0.03747313,
0.1674209,
0.200189,
... |
[Security at work in terms of risk factors (author's transl)]. | Accident epidemiology aims at determining those factors which are associated with an increased risk. Here accidents at work are considered in which any given situation involves: one or many individuals (I); one or many tasks (T); one or many machines or production tools (M); an environment (E). Eight factors are propos... | 370,924 | [
-0.2650892,
-0.1093724,
0.4443832,
0.101895,
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-0.4299934,
-0.05712726,
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0.1636323,
0.2010557,
0.1563315,
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0.1412658,
0.06889839,
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-0.04300101,
-0.07824964,
0.3014607,
-0.02525737,
0.06791139,
-0.2440189,... |
Preliminary results of chemoradiotherapy followed (or not ) by active immunotherapy of stage III and IV lymphosarcoma and reticulosarcoma: correlation of the results with WHO categorization. | One hundred and one patients with advanced (stage III and IV) LS and RS at the first presentation of the disease or on relapse were treated with a regimen combining initial chemotherapy, complementary radiotherapy on "icebergs," supplementary chemotherapy, and finally, active immunotherapy. The overall complete remissi... | 370,939 | [
-0.1603047,
0.2408507,
0.213862,
-0.2291312,
0.0374139,
-0.3330588,
0.1128165,
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-0.1983942,
0.4722153,
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0.1435524,
0.06825966,
0.1884825,
-0.3985456,
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0.3742048,
-0.1270676,
-0.04422583,
0.3718318,
0.2570203,
0.2897967,
-0.2270358,
-0.0... |
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