title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Antimicrobial systems of the surgical wound. II. Detection of antimicrobial protein in cell-free wound fluid. | Human wound fluid contains heat-stable proteins with moderate antibacterial activity against Staphylococcus aureus and Escherichia coli, and different heat-labile proteins with antibacterial activity against E coli. Blood serum also contains heat-labile antibacterial substances, but little heat-stable activity against ... | 404,931 | [
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The influence of a history of a previous test on the prevalence and size of reactions to tuberculin. | Ten millimeters of more of induration to the Mantoux tuberculin test indicates present or past infection with Mycobacterium tuberculosis in the overwhelming majority of cases. Because a number of patients gave a history of a previous positive reaction that was not confirmed on retesting, we carefully evaluated, as part... | 404,946 | [
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Experimental pancreatic islet transplantation. | Transplantation of isolated islets of Langerhans has been suggested as a treatment of certain forms of diabetes mellitus. Injection of 200-400 syngeneic pancreatic islets isolated by collagenase digestion into the pancreas or submandibular gland of diabetic rats rendered most of the hosts nearly normoglycaemic. Blood g... | 404,949 | [
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Enzyme replacement therapy in Gaucher's and Fabry's disease. | Glucocerebrosidase and ceramidetrihexoside-alpha-galactosidase were obtained in a high degree of purity from human placental tissue. The enzymes were infused in Gaucher and Fabry patients, respectively. Following the administration of the proteins to supplement the genetically determined deficiencies, there resulted a ... | 404,951 | [
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[Action of neotelomycin derivatives on bacillus magaterium cells]. | The effect of neotelomycin derivatives on the cells of Bac. megaterium was studied. Derivatives with modification of one of the two active centers of the antibiotic molecule, i.e. the free alpha-amine group of the residue of asparaginic acid or hydrophobic triptophanic structure were studied. The derivative with modifi... | 404,956 | [
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Differential diagnosis between Streptococcus agalactiae and Listeria Monocytogenes in the clinical laboratory. | Streptococci of the group B (S. agalactiae) and Listeria monocytogenes resemble each other in many morphological and biochemical characteristics. Ten beta-hemolytic strains of each species were subjected to 26 tests commonly and easily performed in the clinical laboratory. Macroscopic and microscopic morphology on soli... | 404,952 | [
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Comparative trial of carbenicillin and ampicillin therapy for purulent meningitis. | A randomized therapeutic trial of carbenicillin (CB) or ampicillin (AMP) in purulent meningitis was performed in 86 pediatric and adult patients (41 Haemophilus influenzae, 22 Streptococcus pneumoniae, 13 Neisseria meningitidis, and 10 of unknown etiology). All isolates, incuding H. influenzae, were susceptible to CB a... | 404,962 | [
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Pirbenicillin: comparison with carbenicillin and BL-P1654, alone and with gentamicin, against Pseudomonas aeruginosa. | Minimum inhibitory concentrations (MIC) of pirbenicillin against 135 clinical isolates of Pseudomonas aeruginosa were one-fourth of those required for carbenicillin but two times higher than those for BL-P1654. Increasing the inoculum size produced an adverse effect on the bactericidal activity for all three antibiotic... | 404,963 | [
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Essential fatty acid deficiency in surgical patients. | Parenteral nutrition may protect patients unable to eat from malnutrition almost indefinitely. If fat is not also given EFAD will occur. This outlines a prospective study of 28 surgical patients on total intravenous fat-free nutrition to determine the developmental course of EFAD and the response to therapy. Twenty-eig... | 404,973 | [
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Mucopolysaccharidosis III A (Sanfilippo disease type A). Histochemical, electron microscopical and biochemical findings. | This is a report of two brothers iwth mucopolysaccharidosis. The 8- and 10-year-old boys presented the characteristic clinical symptoms of the syndrome in their entirety. Both had a highly increased excretion of heparan sulfate in urine. The elder boy died and was autopsied and diagnosed as having Sanfilippo disease Ty... | 405,006 | [
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Papular mucinosis with myopathy, arthritis, and eosinophilia. A histopathologic study. | A patient with biopsy-proven papular mucinosis, plus the characteristic IgG lambda light chain paraproteinemia, also developed a severe proximal myopathy, seronegative inflammatory polyarthritis, and marked eosinophilia. Muscle enzymes were elevated, EMG was compatible with polymositis, and muscle biopsy revealed an at... | 405,019 | [
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Histidine-200 alters inhibitor binding in human carbonic anhydrase B. A carbon-13 nuclear magnetic resonance identification. | We have previously prepared 13C-enriched NT-carboxymethylhistidine-200 human carbonic anhydrase B (CmHCAB) by reacting the native enzyme with 90% [1-13C]bromoacetate (Strader, D.J., and Khalifah, R.G. (1976), J. Am. Chem. Soc. 98, 5043). The 13C nuclear magnetic resonance signal of the enriched carboxylate of CmHCAB pr... | 405,036 | [
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Continuous-flow plasmapheresis in management of severe rhesus disease. | Eight patients with severe rhesus disease and expected fetal loss were treated by intensive plasmapheresis using a continuous-flow cell separator. Plasmapheresis was started at 16-27 weeks' gestation, and continued until planned intrauterine transfusion or until the infant was delivered or the rhesus disease became unc... | 405,071 | [
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[Lymphoid cells of the intestinal mucosa with double kappa and lambda specificity in normal man]. | The presence of lymphoid cells possessing both kappa and lambda specificities has been observed in the intestinal mucosa of normal subjects. The variability in the number of such cells in different sections of the same sample and in different subjects seems to be a characteristic of this cell population and may reflect... | 405,121 | [
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[Effect of DDT on the gonadal germ cell population of 5 successive generations of quail embryos]. | The gonadic germ deficit induced by DDT in Quail embryos issued from eggs only treated at the first generation, partially decreases at the second generation and completely at the third. When the DDT treatment is repeated for each generation, the reduced effect slightly increases. | 405,129 | [
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[Demonstration of high affinity binding of estradiol in adrenal cortex tissue]. | Evidence is presented demonstrating the presence of a high affinity (Ka10(8)M-1), limited capacity (3-4 pmoles/mg protein) estradiol binder in the soluble fraction of the Bovine, Rat and Human adrenal cortex. The binding appears specific to the estrogen structure whereas C19 and C21 steroids do not bind. Upon sucrose d... | 405,142 | [
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[Model of the effect of 4-aminopyridine at the level of potassium channels of the giant axon of the squid, Logigo forbesi L]. | Most of the effects of 4-aminopyridine on the potassium conductance of the giant axon of the Squid can be explained in terms of a simple model based on the physicochemical properties of the molecule and what is known about the structure of the potassium "channels". | 405,146 | [
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Low molecular weight (7S) IgM and free light chains in the sera of patients with the tropical splenomegaly syndrome. | The presence of naturally occurring LMW (7S) IgM was suspected on Sephadex G-200 filtration of a serum pool from patients with tropical splenomegaly syndrome (TSS). It was found in nineteen out of thirty-one sera from these patients using a polyacrylamide/agarose gel-diffusion method, and in fifteen of the sera after ... | 405,168 | [
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Blood lymphocytes in chronic lymphocytic leukaemia and Hodgkin's disease: Immunological features and enzymes of nucleoside metabolism. | Purified lymphocytes from venous blood of sixteen healthy adult subjects, eight patients with chronic lymphocytic leukaemia (CLL) and ten with Hodgkin's disease (HD), were examined for adenosine deaminase (ADA), cytidine deaminase (CDA), purine nucleoside phosphorylase (PNPase) and adenosine monophosphate deaminese (AM... | 405,169 | [
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A computer program for long term anticoagulation control. | A computer program is described which calculates suggested daily anticoagulant dose schedules for long term patients. This program is a part of the real-time Information System for Thrombosis Centres. The program requires only the most recent information on the patient from the Information System's data base. This info... | 405,176 | [
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[The phenomenon of synchronization in the status epilepticus produced by penicillin and its changes after Clonazepam (author's transl)]. | The purpose of this series of experiments was to understand how Clonazepam changes the mechanisms of synchronization in seizures. Penicillin was applied to the rabbits cortex. Interictal spikes and seizures were recorded with multiple electrodes from both the cortical surface and intracortically. The spatio-temporal re... | 405,196 | [
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[Prognostic value of the EEG in pre-term and full-term babies (author's transl)]. | Looking for long-term prognostic value of the neonatal EEG, 545 records from 125 children in the pre-term and full-term period have been checked for special criterias: 1. Periods of electrocerebral inactivity (with usual amplifier gain) 2. Relative amplitude reduction over one of the hemispheres or localized 3. Focal c... | 405,197 | [
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[Systematic follow up study of posttraumatic EEG-abnormalities in children (author's transl)]. | A systematic follow up study of EEG in 116 children, who after head injury were admitted to a surgical ward and examined within 3 days, the following day and the 30., 90., and 180. day after the trauma gave the following results; 1. EEG examinations indicate traumatic cerebral disturbances (foci 38%, general slowing 47... | 405,198 | [
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[Electrodiagnostic procedures: special problems in infants and children (author's transl)]. | Electrodiagnostic procedures like elektromyography, studies of nerve conduction velocity, neuromuscular transmission and special reflexes may be performed from the first day of life. The diagnostic value of these investigations in childhood depends especially on the consideration of technical, psychological and develop... | 405,199 | [
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[Analysis of action potentials of muscles by a small general purpose computer (author's transl)]. | To measure the duration of action potentials by a computer, the following steps are necessary: 1. automatic selection of suitable potentials from the EMG 2. identification of equal potentials (action potentials of the single motor unit) 3. measuring the durations of potentials, defined by the distance between first and... | 405,200 | [
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The distribution of luteinizing hormone-releasing hormone (LHRH) in the hypothalamus of the rhesus monkey. Light microscopic studies using immunoperoxidase technique. | Neural structures containing LHRH were characterized in the hypothalamus of the rhesus monkey by four different antisera to the hormone and an immunoperoxidase technique. Immunoreactive perikarya were present in a continuum from the septal-preoptic region anteriorly to the premammillary nucleus posteriorly. These cells... | 405,202 | [
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Synthesis of exported proteins by membrane-bound polysomes from Escherichia coli. | A membrane-bound fraction of polysomes of Escherichia coli has been isolated after lysis of cells without the use of lysozyme. Protein-synthesis studies in vitro show that membrane-bound and free polysomes are different in the following respects. 1. Membrane-bound polysomes synthesize proteins which are exported from t... | 405,218 | [
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Effect of in vivo stimulation of mice on the secretion of factor B of the alternate complement pathway by peritoneal macrophages. | After in vivo treatment of mice with thioglycollate medium, the amount of native factor B which could be detected in vitro in culture supernatants of peritoneal macrophages was much lower than that found in supernatants of macrophages taken from untreated mice. However, when the macrophages from thioglycollate medium-t... | 405,222 | [
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0.07118832,
0.01243457,
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0.02606014,
-0.1045039,
-0.1206531,
0.01854794,
-0.3423052,
-0.2837125,
-0.4237719,
0.4834886,
-0.04333802,
0.2643045,
-0.1140465... |
Pharmacology and function of the myoepithelial cell in the eccrine sweat gland. | Both acetylcholine and a Ca-ionophore, A23187, are comparatively strong stimulants of eccrine sweat secretion in vitro. Nevertheless, the contraction of the secretory coil was seen only after stimulation with acetylcholine but not with alpha or beta adrenergic drugs or with A23187. It was thus inferred that the myoepit... | 405,245 | [
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0.04716598,
... |
Androgenic control of epididymal function in rhesus monkey and rabbit. | The effects of castration and testosterone replacement therapy on the histology and biochemical composition (RNA, DNA, total protein, alkaline phosphatase, acid phosphatase, hyaluronidase, sialic acid, glycogen, phospholipids, and glycerylphosphorylcholine [GPC]) of the epididymis of the rabbit and rhesus monkey were i... | 405,258 | [
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0.02776049,
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0.05295717,
0.01426217,
0.07808606,
-0.1153831... |
Bacteriological studies in a patient with antibiotic-associated pseudomembranous colitis. | Detailed aerobic and anaerobic bacteriological studies on the operative specimen from a patient with antibiotic-associated pseudomembranous colitis revealed approximately 10(11) facultatively anaerobic bacteria, but less than 10(5) obligate anaerobes per g of involved colonic tissue. Fourteen isolates of Escherichia co... | 405,269 | [
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0.1083039,
0.1278748,
0.1091164,
0.07967058,
-0.25... |
Enzyme and chromosome polymorphisms in Japanese natural populations of Drosophila melanogaster. | Collections of D. melanogaster from Japanese populations were analyzed for enzyme and chromosomal polymorphisms. Allelic frequencies at the Adh and alphaGpd loci were compared with polymorphic inversion (In(2L)B, In(2R)C) frequencies in the second chromosome. There was a significant positive correlation between the fre... | 405,274 | [
0.04793312,
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0.3479425,
-0.3966773... |
Genus Aotus Q- and G-band karyotypes and and natural hybrids. | Q- and G-banding studies of Aotus trivigatus trivirgatus and Aotus trivirgatus griseimembra are presented. After the analysis of 8 specimens, 2 A.t. trivirgatus and 6 A.t. griseimembra and the review of the literature on the field we state the existence of two different karyotypes, 2n = 54 and 2n = 50, for A.t. trivir... | 405,286 | [
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0.022987,
0.4106651,
0.1158031,
-0.2674507,
-0.... |
Sequence of eruption of permanent teeth and epiphyseal union in three species of African monkeys. | Sequences of eruption of teeth and union of epiphyses determined for three species of African Cercopithecinae. These sequences are highly scalable and are highly comparable between among the species. Some sex differences in sequence were found within each species. The sequences of epiphyseal union in these species of O... | 405,287 | [
-0.04631101,
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0.06779258,
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Probable assignment of the serum cholinesterase (E1) and transferrin (Tf) loci to chromosome 1 in man. | Suggestions of linkage in males between the E1 and Rh loci (Z = + 1.849; THETA = 0.20) and between the Tf and Rh loci (Z = + 0.595; THETA = 0.35) are presented. The assignment of the E1 and Tf loci to chromosome 1 and the order Tf:E1:PGD:Rh:PGM1 are cautiously proposed. | 405,310 | [
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Isolation and identification of the Cmicron4-domain of IgM. | Intact Cmicron4-domain was isolated by molecular exclusion chromatography of reduced and alkylated Fc5 micron prepared by tryptic digestion at 60 degrees C of a monoclonal IgM. Two fragments were obtained of which one contained carbohydrate and the other none. These fragments were successfully separated by chromatograp... | 405,314 | [
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Assay of Escherichia coli heat-labile enterotoxin with vero cells. | The continuous cell line of African green monkey kidney, Vero, showed characteristic morphological changes in response to culture filtrates from toxigenic strains of Escherichia coli. The response compared favorably with that of Y-1 (mouse adrenal) and CHO (Chinese hamster ovary) cells. Vero cells were the simplest and... | 405,326 | [
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... |
A reappraisal of the forces involved in hemagglutination. | The underlying principles governing the second stage of hemagglutination, as described in 1965, have been reevaluated. This reappraisal reaffirms that red cell aggregation is dependent on the potential energy barrier (zota) between erythrocytes. This in turn is dependent on the ionic strength and dielectric constant of... | 405,333 | [
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0.00553285,
0.2736233,
0.02610358,
-0.179817,
... |
Stimulation of pig lymphocytes with anti-immunoglobulin serum and mitogens. | Mitogenic stimulation of pig lymphocytes by anti-immunoglobulin serum and by Con A, PHA, PWM and LPS has been measured by 3H-thymidine incorporation. Lymphocytes from blood, spleen and lymph node were readily stimulated by antiglobulin. Specific anti-micron serum was mitogenic for blood lymphocytes, indicating that tho... | 405,334 | [
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-... |
Pseudomonas protease. Purification, partial characterization, and its effect on collagen, proteoglycan, and rabbit corneas. | The extracellular protease of a virulent strain of Pseudomonas aeruginosa was purified by DEAE-cellulose chromatography in two steps. SDS-polyacrylamide gel electrophoresis of the purified enzyme revealed a single band, and the enzyme was shown to be the major component of the bacterial filtrate. The protease was fully... | 405,343 | [
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0.378... |
Retinal damage from long-term exposure to laser radiation. | The maculae of rhesus monkeys were exposed to an argon-ion lazer operated in the TEM00 continuous wave mode at a wavelength of 514.5 nm. Both ophthalmoscopic and histopathologic evaluations of exposure sites were obtained. Threshold (ED50) values were obtained for 0.5, 5, 30, 120, and 1,000 sec. exposure times. Presenc... | 405,344 | [
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0.01066497,
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0.2903296,
... |
Hyperviscosity syndrome associated with lymphocytic leukemia in three dogs. | Hyperviscosity syndrome was associated with increased plasma content of monoclonal immunoglobulin (IgA or IgM) in 3 dogs with lymphocytic leukemia. The diagnosis of lymphocytic leukemia was based on the finding of a large number of mature lymphocytes in the blood and bone marrow. The clinical signs included weakness, l... | 405,353 | [
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0.09796014,
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... |
Mode of action of the protein, SP127, which enhances the activity of macrolide antibiotics against Pseudomonas aeruginosa. | Antibiotics, the activity of which enhanced against Pseudomonas aeruginosa by SP127, were restricted to the basic macrolide antibiotics such as erythromycin, maridomycin and oleandomycin, the neutral macrolide antibiotics such as lankamycin and lankacidin C, vancomycin and enramycin. Synergistic activity of SP127 with ... | 405,356 | [
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0.07562233... |
Skin, preoptic, and core temperatures influence behavioral thermoregulation. | Squirrel monkeys (Saimiri sciureus) will learn to regulate their chamber air temperature (Ta) behaviorally by selecting between two air temperatures, 10 and 50 degrees C. When transient (10-min) displacements of local preoptic temperature (Tpo) are made around neutral, via water-perfused thermodes, changes in Ta select... | 405,366 | [
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0.1600181,
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0.1538653,
-0.04468749... |
Subfractionation of rat liver microsomes by immunoprecipitation and immunoadsorption methods. | Rabbit antisera were prepared against cytochrome b5 and NADPH-cytochrome c reductase [EC 1.6.2.4] purified from rat liver microsomes, and utilized in examining the distribution of these and other membrane-bound enzymes among the vesicles of rat liver microsomal preparations by immunoprecipitation and immunoadsorption m... | 405,382 | [
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0.07... |
Cellular localization of tyrosinase in human malignant melanoma cell lines. | Human malignant melanocytes show characteristic morphologic modifications which are particularly evident in their specific organelles: melanosomes. These modifications are conserved in cell culture. The ultrastructural localization of tyrosinase, the enzyme which converts tyrosine and dopa into melanin, was determined ... | 405,430 | [
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0.523999,
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-0.1485752,
0.2172... |
An in vitro measurement of bleeding time. | An in vitro method of measuring the bleeding time is described. The test, called the machine bleeding time (MBT), is not affected by heparin and detects the same types of hemostatic abnormalities as the template bleeding time. It is sensitive to thrombocytopenia, aspirin administration, and von Willebrand's disease. It... | 405,442 | [
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0.2505446,
0.5837945,
-0.2701852,
-0.03523274,
-0.... |
Long-term behavioral changes in the rhesus monkey after multiple daily injections of d-methylamphetamine. | The effects of multiple daily injections of d-methylamphetamine on spaced lever-press responding were investigated in the rhesus monkey. Responding was measured after single injections of d-mehtylamphetamine (0.0625-1.0 mg/kg) both before and after the monkeys were maintained on a multiple daily d-methylamphetamine inj... | 405,473 | [
-0.2482157,
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0.3195263,
0.2052991,
-0.09134125,
0.2562005,
... |
Regulation of ciliary pattern in ciliates. | The modes of pattern regulation found in the ciliates Dileptus and Paraurostyla are compared. These forms are systematically distant but both possess very extensive regenerative capacities. They are characterized by 2 types of ciliary patterns: the ciliature of Dileptus has largely a simple pattern composed of single k... | 405,481 | [
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0.2109009,
-0.06315128,
0.1040932... |
[Ormiersia carcini gen. n., sp. n., microsporidian of the Mediterranean crab, Carcinus mediterraneus Czerniavsky, 1844: developmental cycle and ultrastructural study]. | A microsporidan parasite, Ormieresia carcini gen. n., sp. n., was found in the crab, Carcinus mediterraneus Czerniavsky. Its development and fine structure are the subject are the subject of the present study. The life cycle begins with a schizont surrounded by a unit membrane and containing a diplokaryon. The entire p... | 405,486 | [
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0.1134792,
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0.7817006,
-0.04308332,
0.... |
Radioimmunoassay for myeloma idiotype. | Rabbit anti-idiotype antisera were prepared against four human myeloma proteins. These antisera demonstrated a capacity to bind the 125I-labeled autologous purified monoclonal IgG, but failed to demonstrate any binding to 125I-labeled normal IgG or to labeled myeloma IgG obtained from other myeloma patients. The anti-i... | 405,500 | [
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0.3645242,
0.000890974,
-0.05070584,
... |
[Clinical aspects of diabetic nephroangiopathy (author's transl)]. | Diabetic nephropathy is a dangerous and insidious complication of diabetes mellitus. The course is variable and from the statistical point of view usually unfavorable. The pathogenesis of the complaint is not fully known. Of the numerous hypotheses, the one most favored is a defective glucose metabolism with uncontroll... | 405,565 | [
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0.1743397,
-0.1487153,... |
Computed tomography or orbital lesions. A cooperative study of 210 cases. | Computed tomography (CT) has given us a new method for examining the orbit and its contents. The technique of examination is described, and the indications for the application of computed tomography in ophthalmology are considered: suspected orbital tumors, unilateral exophthalmos, pareses of the ocular muscles, trauma... | 405,623 | [
-0.1139803,
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0.04717945,
0.1032613,
-0.05405021,
0.1485446,
0.09893299,
-0.20191... |
Sensations of ocular movement in seizures originating in occipital lobe. | Two patients with structural lesions had illusions of eye movement as the earliest manifestation of their seizures. One patient had a right occipitoparietal arteriovenous malformation and the other had a tentorial meningioma encroaching on the left occipital lobe. Symptoms were controlled by anticonvulsants and subsequ... | 405,625 | [
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0.1051631,
0.02207998,
-0.3485678,
0.02804872,
-0.01260281,
-0.20469... |
Detection of orbital and intraocular foreign bodies by computerized tomography. | Localization of intraocular and orbital foreign bodies with computerized tomography (CT) was evaluated in eight patients and an experimental model. CT examination was particularly helpful in cases with multiple similar foreign bodies and in identifying foreign bodies too radiolucent to be seen by standard skull x-rays.... | 405,643 | [
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... |
Sequence analysis of the 3' non-coding region of mouse immunoglobulin light chain messenger RNA. | Using an oligonucleotide d(pT10-C-A) as primer, cDNA has been transcribed from the 3' non-coding region of mouse immunoglobulin light chain mRNA and sequenced by a modification1 of the 'plus-minus' gel method2. The sequence obtained has partially corrected and extended a previously obtained sequence3. The new data cont... | 405,661 | [
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Serum magnesium and irradiation. | Serum magnesium determinations were obtained on 10 dogs and 11 patients undergoing fractionated irradiation to the pelvis and lower abdomen. Five of dogs received oral prednisone during irradiation. There was no significant change in magnesium concentration in either the control dogs or the patients, but there was a si... | 405,709 | [
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Immunochemistry of prostaglandin endoperoxide-forming cyclooxygenases: the detection of the cyclooxygenases in rat, rabbit, and guinea pig kidneys by immunofluorescence. | Rabbit antiserum has been prepared against the prostaglandin endoperoxide-forming cyclooxygenase (EC 1.14.99.1) purified from sheep vesicular glands. Ouchterlony double diffusion and immunoelectrophoretic analyses indicate that the anti-cyclooxygenase serum is monospecific for the enzyme. The anti-cyclooxygenase serum ... | 405,716 | [
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Myocardial fibrinolytic activity in allogenic cardiac rejection. | The relationship between alterations in myocardial fibrinolytic activity and the degree of graft tolerance or rejection was studied in 22 nonimmunosuppressed heterotopic cardiac transplants in chacma baboons. Fibrinolysis was evaluated on tissue sections and tissue extracts. Fibrinolytic activity was compared with elec... | 405,762 | [
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[Structural organization of the prefrontal cortex in cats and differences between it and the same area in monkeys]. | It has been demonstrated that similar to that in monkeys, prefrontal dorso-lateral cortex in cats significantly differs from the medio-basal cortex not only in the structure and level of differentiation, but also in its thalamic projections. In cats, definite topography in the distribution of projections from the medio... | 405,824 | [
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Antifertility properties of bovine pineal extracts: reduction of ovulation and pre-ovulatory luteinizing hormone in the rat. | Bovine pineal glands were extracted with acetic acid and partially purified on Sephadex G-25. Three fractions, F3, F4 and F5, were each administered to cycling female rats for 4, 2 or 1 day prior to ovulation to determine their effects on fertility, ovulation and the pro-oestrous surge of luteinizing hormone (LH). The ... | 405,831 | [
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The thyrotrophin response to thyrotrophin releasing hormone during treatment in patients with Graves' disease. | Thyrotrophin releasing hormone (TRH) tests were performed at 4 or 8 weeks intervals, after the initiation of anti-thyroid treatment in 15 patients with Graves' disease. All TRH test were negative as long as the serum levels of thyroxine (T4) and triiodothyronine (T3) were elevated, and normalization of the serum levels... | 405,834 | [
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Xeroradiography in radiation therapy. | The xerographic technique has been introduced at Radiumhemmet for direct field control in therapy with high energy photon radiation (60Co-unit, 6 MV linear accelerator and 42 MeV betatron). The xerograms are of a sufficiently good quality for this purpose. The advantages and disadvantages connected with the xerographic... | 405,841 | [
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Arrangement of connective tissue components in the walls of seminiferous tubules of man and monkey. | In primates the membrane separating the seminiferous epithelium from the interstitial space is composed of one to three (monkey) or two to six layers (man) of myoid cells associated with one to two layers of fibrocyte-like adventitial cells. All these cells are separated from each other by irregular spaces filled with ... | 405,855 | [
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Thoracic dysplasia in spondyloepiphyseal dysplasia congenita. | Spondyloepiphyseal dysplasia congenita (SED congenita) can involve the ribs. The result is rib shortening, a dysplastic thorax that is not only short but also narrowed, and respiratory failure. This case involves an infant who died of respiratory failure 36 hours after birth. A dysplastic small volume thorax in infancy... | 405,862 | [
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New opportunities for the public to shape the nation's institutional health care services. | The author of this Comment describes how recent federal legislation (P.L. 93-641, signed into law in January, 1975)--and improved scientific techniques for integrating (1) community medical needs assessment, (2) institutional budgeting linked to regional/state health plans, and (3) budget ceilings--have given the publi... | 405,864 | [
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The influence of reserpine and ethylenediaminetetraacetic acid (EDTA) on serotonin storage organelles of blood platelets. | The present investigation has evaluated the influence of reserpine on the serotonin-rich organelles bodies) in platelets from dogs, rabbits, and humans. Reserpine markedly depresses the levels of stored serotonin in human and animal platelets, accompanied by a small decrease in platelet ATP but no change in platelet AD... | 405,872 | [
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Attempts to immunize monkeys against Plasmodium knowlesi by using heat-stable, serum-soluble antigens. | Thirty-six Macaca mulatta monkeys were immunized with different concentrations and regimens of heat-stable, serum-soluble (S-) antigens of Plasmodium knowlesi prior to challenge with the homologous parasite via sporozoite inoculation. Fewer deaths and reduced maximum parasitemias occurred in those animals inoculated wi... | 405,876 | [
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[Parenteral nutrition in management of sick low birth weight infant (under 2,000 g.) (author's transl)]. | A serie accounting for 32 newborn sick infants with a mean weight of 1,324 g. and gestational age of 30.6 weeks in whom parenteral nutrition was applied alone or as supplementation of oral alimentation is presented. The mean duration was of ten days, and mean weight increment of 14.6 g. Infectious complication were the... | 405,896 | [
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Present otologic status of subjects implanted with auditory prostheses. | Thirteen persons who had functioning cochlear prostheses underwent medical evaluation. The nine males and four females ranged in age from 26 to 67 years at the time of the evaluation. Their mean age was 48.1 years. The etiology of deafness had been determined prior to implant surgical procedures in 6 of the 13 subjects... | 405,907 | [
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Present neuropsychological status of subjects implanted with auditory prostheses. | To assess the subject's cognitive and conceptual function, an extensive battery of neuropsychological tests were administered to each subject. Of the 13 subjects, 11 showed normal to superior cognitive and conceptual abilities; however, two of the subjects presented evidence of impaired cognitive and conceptual functio... | 405,911 | [
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Simple, effective method for purifying the AS-1 cyanophage. | Highly infectious, purified AS-1 virus was obtained by treating virus-induced culture lysates with bentonite followed by rotary evaporation concentration and density gradient centrifugation. | 405,927 | [
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[The mitral apparatus and surgery of sub-valvular aortic stenosis]. | The authors present three eases of subvalvular aortic stenosis caused by an abnormality of the mitral valve mechanism which required placement of a prosthetic valve. They describe the types of mitral valve abnormality which are reported in the literature to have caused obstruction to the aortic outflow tract. They anal... | 405,940 | [
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[Value of dacron aortoplasty in the treatment of coarctation of the aorta during the 1st six months of life]. | Between September 1st 1974 and June 1st 1976, 12 infants under the age of 6 months have been operated on by a dacron patch aortoplasty for coarctation of the aorta. The associated lesions were a patent ductus arteriosus in each case, a VSD in 8 cases, and a trans-position of the great arteries in 5 cases. A pulmonary a... | 405,942 | [
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0.017... |
[Choice of surgical method in the child or adult (excluding infants) suffering from coarctation of the aorta and severe cardiopathy]. | A study of a serie of 45 cases of coarctation of the aorta associated with a severe cardiac lesion or malformation, and treated at a single operative session (18 cases) or in two consecutive stages (27 cases) has produced the following conclusions: --Treatment at a single operation is possible, usually at the cost of t... | 405,943 | [
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... |
[Right juxtaposition of the atria. Apropos of one case without associated trunco-conal abnormalities]. | A child of 7 had coarctation of the aorta and an atrial septal defect. In the course of surgery to close the septal defect, she was found to have a right-sided juxtaposition of the appendages. This is a very rare abnormality, with no symptoms of its own, but usually associated with severe cardiac malformations especial... | 405,949 | [
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Mapping of nucleoside phosphorylase (Np-1) and esterase 10 (Es-10) on mouse chromosome 14. | A method for detecting two alleles at Np-1 (nucleoside phosphorylase) and three alleles at Es-10 (esterase 10) from mouse blood by cellulose acetate electrophoresis is described. The allelic constitution at these loci for 44 inbred strains and stocks was determined. The location of Np-1 on chromosome 14 was established... | 405,970 | [
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Problems posed by potential gonococcal vaccines viewed from the vantage point of a control agency. | Progress in the characterisation of Neisseria gonorrhoeae and other bacterial pathogens has suggested that immunoprophylaxis for gonorrhoea may be possible despite the well-known propensity for reinfection. Pili, outer membrane proteins, a capsular polysaccharide, and the lipopolysaccharide may be important gonococcal ... | 406,011 | [
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Similar C-phycocyanins from two strains of thermotolerant cyanophyte Mastigocladus laminousus. | C-phycocyanin from two strains of the thermotolerant blue-green alga, Mastigocladus laminosus (NZ-DB2-m and I-30-m), that grow within different temperature ranges have been characterized with respect to aggregation, immunologic properties, subunit composition, and thermodenaturation. The critical thermal-denaturation t... | 406,021 | [
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The orthonitrophenyl-beta-D-galactoside hydrolase from Pseudomonas aeruginosa (0: 11 serotypes) is a superficial enzyme. | About 95% fo the 0: 11 strains of Pseudomonas aeruginosa was able to hydrolyze orthonitrophenyl-beta-D-galactopyranoside (ONPG), but was unable to use lactose. The ONPG-hydrolyzing enzyme was located essentially in the periplasm, as seen by biochemical and ultrastructural studies. | 406,028 | [
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[Fluorogenic amines in the notochords of chick embryos treated by cholinergics]. | The investigation of 3 day old notochords by the fluorescence method of Falck and Owman showed an increase of the fluorescence after treatment of the chick embryos at 48 hrs of incubation, with nicotine sulfate or carbachol. The addition of norepinephrine or L-Dopa emphasized the formaldehyde induced fluorescence. The... | 406,060 | [
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[Secretion of insulin and of glucagon by the perfused pancreas of newborn rats: effect of vasoactive intestinal peptide Vip]. | A method is described for perifusion of the splenic part of the pancreas from 48-64 hour-old rat. In different basal conditions, the secretion of insulin and glucagon is stable and reproducible for 90 mn. The addition of the vasoactive intestinal peptide (VIP) to these perifusion media, at a concentration as low as 2 n... | 406,070 | [
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0.1040288,
0.05... |
[Induction of the mesoderm and primordial germ cells by the endoderm of Pleurodeles waltlii (Amphibia, Urodele): development during gastrulation]. | Blastulae ectoderm is combined with dorsal or ventral endoderm from blastulae, gastrulae and early neurulae. In vitro culture reveals the presence of different mesodermal structures whose nature is connected with the endoderm origin site. Primordial germ cells differentiate essentially in the recombinates including ven... | 406,093 | [
0.091847,
-0.1897792,
-0.2020516,
-0.1575511,
0.1170596,
-0.3841012,
-0.3026398,
-0.01807477,
0.1339444,
0.1382429,
0.1080758,
0.1425269,
-0.04562445,
-0.2847576,
-0.381507,
-0.4463852,
-0.440667,
0.03252759,
-0.03656173,
0.1506927,
0.6650212,
0.1084213,
0.05088667,
-0.... |
Antigens in pigeon breeder's disease: the use of pigeon dropping antigens in detecting antibody activity. | Sera from patients with pigeon breeder's disease were analysed for precipitating antibodies by immunodiffusion and immunoelectrophoresis using whole pigeon dropping extract (PDE) and a purified fraction of PDE (PDE1) as antigens. For comparison, sera from asymptomatic pigeon breeders and normal individuals were also te... | 406,101 | [
-0.5106992,
-0.06010445,
-0.01721086,
-0.2776694,
0.1220121,
-0.04614203,
-0.2128629,
0.1788676,
-0.02443493,
-0.03120721,
0.4333145,
0.3798419,
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-0.1356559,
-0.1625844,
0.09913024,
-0.6339605,
0.1529468,
0.06852629,
0.202869,
0.001292434,
0.1045782,
-0.125368... |
Effect of sulpiride on serum growth hormone and prolactin concentrations following L-DOPA administration in man. | The effect of chronic administration of sulpiride on serum human growth hormone (hGH), prolactin and thyroid stimulating hormone (TSH) was examined in 6 normal subjects. Sulpiride was given orally at a dose of 300 mg (t.i.d.) for 30 days. Sulpiride raised serum prolactin levels in all subjects examined. In addition, su... | 406,134 | [
-0.2499083,
-0.2808939,
-0.1157082,
-0.1595535,
0.4291029,
-0.1297027,
-0.1227308,
-0.3276414,
-0.09138234,
0.1318462,
0.131299,
0.2215021,
-0.3356775,
0.4749291,
0.08390732,
0.001635314,
-0.3688264,
0.01460244,
0.06883152,
0.1142808,
0.04947425,
0.3258355,
-0.1076728,
... |
Peptide mapping of the lambda-like chains of the BASILEA rabbits. | The recently established mutant strain of rabbits, named BASILEA, lacks the k polypeptide L-chain which is replaced by a lambda-like type (bas). This is evident from the amino acid composition and peptide maps of the bas L-chain when compared to the L-chains of the rabbits suppressed for the expression of the b locus a... | 406,142 | [
0.09200376,
0.09525736,
-0.3229977,
0.1615925,
0.1059786,
-0.1084552,
-0.1610762,
0.04976501,
0.2406207,
0.2123677,
-0.04046792,
0.1305082,
0.2057403,
0.2051886,
-0.4462833,
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-0.3483683,
0.0982561,
0.5629394,
0.02832678,
0.3549587,
0.140717,
-0.0347698,
-0.31... |
Pathology in rabbits treated with leukocyte-degraded meningococci in combination with meningococcal endotoxin. | The effects of a preparative dose of the leukocyte egesta containing degraded meningococci and a provocative dose of the meningococcal lipopolysaccharide on development of pathological lesions associated with disseminated intravascular coagulation were studied in tissues of 32 rabbits. These effects were compared with ... | 406,202 | [
0.04831075,
-0.1210738,
-0.07914053,
-0.1591528,
-0.09142502,
-0.4590903,
-0.3330112,
0.03626873,
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0.01723246,
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0.07782017,
0.2184057,
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0.05094069,
-0.1114547,
-0.1471802,
0.09058955,
0.4610675,
0.4425072,
0.430755,
0.1037581,... |
Preparation and properties of a specific antiserum against human liver. | Immunization of rabbits with a soluble human liver fraction incorporated into Freund's adjuvants produced antibodies that reacted with human liver extracts as well as extracts of other human organs. Absorption of the antihuman liver sera (AHLS) with lyophilized human serum, heart, and kidney abolished the reactions wit... | 406,206 | [
-0.2707838,
-0.008171299,
-0.2635438,
0.001712464,
0.1173595,
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-0.3457653,
0.1482587,
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0.08095042,
0.179822,
0.1903799,
0.4175043,
-0.1757579,
-0.5791404,
-0.1957932,
-0.5161147,
-0.1823733,
-0.3740791,
0.3445252,
-0.07098716,
0.04875903,
-0.3552682... |
Decalcified bone as a substrate for osteogenesis. An appraisal of the interrelation of bone and marrow in combined grafts. | This paper examines the fate of decalcified allografts (homografts) of iliac cancellous bone impregnated with autologous red marrow and implanted intermuscularly into the anterior abdominal wall of rabbits. In contrast to the findings of Urist and other workers that cortical bone decalcified with hydrochloric acid (HCl... | 406,261 | [
-0.1644496,
-0.0767211,
0.06941636,
0.04978386,
0.04361219,
-0.3465224,
-0.05810839,
0.1896158,
0.1929868,
-0.002321509,
0.1011985,
-0.1413301,
0.1022338,
-0.2590849,
-0.7550297,
0.06659223,
-0.3501454,
-0.1885983,
-0.3700848,
0.05943365,
0.1233539,
0.2803596,
-0.00414296... |
Quantitative determination of nuclear pore complexes in cycling cells with differing DNA content. | The number of pore complexes per nucleus was determined for a wide variety of cultured cells selected for their variable DNA content over a range of 1-5,6000. The pore number was compared to DNA content, nuclear surface area, and nuclear volume. Values for pore frequency (pores/square micrometer) were relatively consta... | 406,262 | [
-0.03693717,
0.1744653,
0.1065737,
0.2365598,
0.1829269,
-0.1722648,
-0.2067771,
0.1752119,
0.4285547,
0.264443,
-0.09211411,
-0.2260984,
0.08501311,
-0.04490795,
-0.566431,
-0.2125075,
-0.5248671,
-0.08338568,
0.04263582,
0.07567736,
0.6167497,
0.04206686,
-0.2020178,
... |
Prostaglandin F2alpha binding sites in human corpora lutea. | The specific binding of 3H-prostaglandin (PG) F2alpha to homogenates of human corpora lutea of the cycle and ectopic pregnancy was examined. Corpora lutea of ectopic pregnancy bound significantly (P less than 0.01) higher amounts of added 3H-PGF2alpha than those of the luteal phase of the menstrual cycle. The 3H-PGF2al... | 406,267 | [
-0.054872,
0.01826267,
-0.4017845,
0.05722145,
-0.1920033,
0.02215447,
-0.1370916,
-0.0181818,
0.3072256,
0.05891391,
0.06515892,
0.6529533,
-0.05808735,
-0.02860626,
-0.3628428,
0.02024969,
-0.4217238,
-0.1730414,
0.229948,
0.3359415,
0.2618155,
0.6139273,
-0.3490654,
... |
The gray scale appearance of the normal pregnancy from 4 to 16 weeks of gestation. | Since the advent of gray scale, more detail is available on sonograms and the products of conception are more readily seen. The gestational sac can be seen at about the fifth week of gestation and the fetal parts can be recognized around the seventh week of gestation. The gestational sac, fetal parts, and the placenta ... | 406,289 | [
-0.07500707,
0.2663879,
-0.4449782,
0.1333523,
0.4104627,
-0.1335673,
-0.2027463,
-0.09516988,
0.2031644,
-0.08230992,
0.1619528,
-0.1652713,
0.1098878,
-0.1669016,
-0.4698934,
-0.1049289,
-0.3464753,
0.260721,
0.007741771,
-0.07791502,
0.3070186,
0.3129334,
-0.1397568,
... |
The structural basis of rabbit VH allotypes: serologic studies on a1 H chains with defined amino acid sequence. | The amino acid sequences for the VH regions of three homogeneous antibodies elicited by type III pneumococcal vaccine were determined. All three antibodies had the group a allotype a1. Two of the antibody H chains (3372, 3381) had identical amino acid sequences in all framework positions that are considered correlates ... | 406,325 | [
-0.2234934,
0.1123186,
-0.207022,
-0.3580818,
0.07876991,
-0.3060424,
-0.04737354,
0.004874676,
0.2616221,
0.3278512,
0.2497552,
-0.06482936,
0.05206027,
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-0.160816,
0.04637365,
-0.1743433,
0.007509886,
-0.1837456,
0.2041219,
0.3485268,
0.2143401,
-0.1729991,
... |
A solid phase fluorescent immunossay for the quantitation of the C4 component of human complement. | A non-competitive method for the determination of the C4 component of human complement in serum is described. This procedure involves use of a specific antibody covalently attached to derivatized polyacrylamide beads and a fluorescently labeled specific antibody. Reproducible results were achieved for C4 in serum in th... | 406,329 | [
-0.1545602,
0.2687933,
0.1080569,
0.09888031,
0.09510216,
0.1379551,
-0.09115106,
0.5061252,
0.07148527,
0.1257433,
0.1004143,
-0.05589746,
0.02076879,
-0.3180453,
-0.3188094,
-0.3072149,
-0.4538838,
0.06078549,
-0.2341314,
0.1648726,
0.1250211,
0.08958726,
0.0230788,
-... |
Phage receptor material in Lactobacillus casei. | In Lactobacillus casei S-I, D-galactosamine and L-rhamnose comprised a phage receptor for phage J-I. A mixture of D-galactosamine and L-rhamnose effectively inactivated phage J-I, and a J-I-resistant mutant strain, L. casei S-I/J-I, lacked D-galactosamine in its surface component. The phage-inactivating effects of D-ga... | 406,350 | [
0.1803957,
-0.2617533,
-0.09182939,
0.4348855,
0.4286914,
0.06477854,
-0.3205533,
0.05847525,
0.2866412,
0.00098204,
0.08535238,
0.2028191,
-0.2141935,
-0.03223425,
-0.3363124,
-0.05196725,
-0.526875,
0.04463283,
-0.00921409,
-0.108874,
0.3795313,
0.2453419,
-0.1160329,
... |
Transfer and expression of pseudomonas plasmid RP1 in Caulobacter. | This study demonstrates that the host range of Pseudomonas plasmid RP1 includes the genus Caulobacter. Caulobacter was shown to acquire three antibiotic resistance markers located in RP1. A fourth plasmid marker, susceptibility to an RNA bacteriophage, was not expressed, but could be transferred from Caulobacter to Esc... | 406,354 | [
-0.1703844,
0.01532898,
-0.04173598,
-0.2173796,
-0.2560262,
-0.6352658,
-0.3243564,
-0.03913437,
0.2041786,
0.03180681,
0.5149332,
0.3483105,
-0.3407216,
0.01701925,
-0.2712497,
0.005536147,
-0.2143251,
0.1867081,
0.254558,
-0.3321033,
0.02798563,
-0.1310318,
-0.2141629,... |
Urinary riboflavin metabolites in the rat. | Male rats were fed a riboflavin-deficient diet for 25 days and then fed [2-14C]riboflavin to replete their riboflavin pool(s). During a second depletion period, urine and feces were collected and 14C excretion monitored. The urine was chromatographed on R-15 resorcinol resin and 14C was measured in all fractions. The 1... | 406,370 | [
-0.1136135,
0.2862433,
0.09710544,
-0.2344999,
0.4363979,
-0.4094727,
-0.2194605,
0.2186949,
-0.1887872,
0.2471725,
0.2767973,
0.3492565,
-0.1575708,
0.4151372,
-0.4549432,
0.3868117,
-0.3437146,
0.1863584,
-0.08720674,
0.06924859,
0.2383416,
0.346889,
-0.04157261,
0.16... |
Metabolism of uracil-containing DNA: degradation of bacteriophage PBS2 DNA in Bacillus subtilis. | When Bacillus subtilis is infected by the uracil-containing DNA phage PBS2, the parental DNA labeled with radioactive uracil and cytosine remains acid insoluble. If the synthesis of the phage-induced uracil-DNA N-glycosidase inhibitor is prevented, the parental DNA is completely degraded to acid-soluble products beginn... | 406,424 | [
-0.1505937,
0.09521438,
-0.3300171,
-0.02443385,
0.2215853,
-0.2439066,
-0.2821496,
0.01039993,
0.1070573,
0.1613472,
0.2965619,
0.1468385,
-0.0926873,
0.09746048,
-0.4558089,
0.07368731,
-0.08118955,
-0.1676333,
0.1239791,
-0.03108807,
0.4801326,
0.1523572,
-0.4122379,
... |
Prophage F116: evidence for extrachromosomal location in Pseudomonas aeruginosa strain PAO. | F116 is a temperate-generalized transducing phage of Pseudomonas aeruginosa. Genetic evidence leads to the conclusion that F116 prophage DNA is maintained extrachromosomally as a plasmid. Preliminary physical evidence is presented to support this hypothesis. | 406,425 | [
-0.2292491,
-0.1723578,
-0.2267545,
0.1311381,
0.05188699,
-0.2102077,
-0.344918,
0.05581825,
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-0.2269974,
0.1530578,
0.03286401,
-0.003402056,
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-0.1331525,
-0.1246056,
0.1559223,
0.09205911,
-0.2638064,
-0.265181,
0.1460027,
-0.2860496,... |
Correlation of perineal detumescence and ovulation in the pigtail macaque (Macaca nemestrina). | A study was made of the relationship between ovulation and perineal detumescence in the pigtail macaque (Macaca nemestrina). Daily laparoscopic examation of both ovaries was made beginning on the 9th day of the menstrual cycle. The appearance of the ovaries was recorded and photographs were taken of the perineum and ov... | 406,480 | [
0.1249631,
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-0.1672407,
-0.1677295,
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-0.3489873,
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0.1738228,
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0.1283637,
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-0.1362424,
-0.4172684,
0.1014467,
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-0.5074281,
0.128471,
0.2236222,
-0.2620744,
-0.1992117,
0.1214941,
-0.06582145,
... |
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