title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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[Immunosuppressive treatment of multiple sclerosis. 4. Results of treatment with azathioprine and antilymphocyte globulin (author's transl)]. | During the long-term treatment with azathioprine of 79 patients suffering from MS there was a significant reduction in the relapse rate; the course of the disease was also favorabley influenced. In about one third of the patiens afflicted with the chronic progressive form of MS, there was no further progression. After ... | 408,666 | [
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Sensitivity of wild type and recombination-deficient strains of Drosophila melanogaster to ultraviolet radiation. | The sensitivity of Drosophila melanogaster to ultraviolet light has been studied in wild type and recombination-deficient strains. Survival was measured as the proportion of irradiated embryos or larvae which developed to adult flies. In view of the fact that males of this species do not participate in meiotic recombin... | 408,677 | [
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Chronic intravenous dosing and blood collection in the unanesthetized monkey. | A procedure is described which allows chronic dosing and blood collection from awake monkeys. The procedure involves only minor surgical anesthesia and allows the same vein of the animal to be used several different times with home-cage recuperation periods intervening between sequential chronic catheterizations. | 408,826 | [
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Comparative study of retrograde amnesia in rats on active and passive avoidance tasks and spontaneous recovery of memory. | Naive and pretrained rats were trained in two active avoidance paradigms using a pole-climbing box and in a single-trial passive avoidance task using a T-maze. They were then subjected to amnestic treatments with electroshock, leptazol, pentobarbitone, or ether anesthesia. Single retention tests were given at 20-24, 44... | 408,859 | [
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Uptake inhibition of biogenic amines by newer antidepressant drugs: relevance to the dopamine hypothesis of depression. | The dopamine theory of depression was studied by assessing the effect of antidepressant drugs on uptake of dopamine, noradrenaline, and serotonin in synaptosomes from rat brain. Five newer drugs--butriptyline, maprotiline, trimipramine, iprindole, and mianserine--exhibited rather potent inhibition of 3H-dopamine uptake... | 408,861 | [
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The effects of amphetamine on maze learning by goldfish. | Goldfish performed a simple left-right discrimination in a Y-maze under the influence of amphetamine. The subjects showed facilitation of learning at a low dose (1.25 mg/l) but not at 2.0 mg/l. | 408,863 | [
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[Multiple and familial meningiomatosis. A syndrome bordering on Recklinghausen's neurofibromatosis]. | The authors present three cases of multiple, intra-cranial meningiomatosis with contact hyperostosis affecting the grandmother, mother and daughter, in a very stereotypic manner. No other sign of von Recklinghausen's disease was noted, except for two tiny neurofibromas on the left hand in the mother. Only the latter su... | 408,890 | [
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A study of the variable heavy chain (VH) regions in human polyclonal IgM rheumatoid factors. | Ten IgM polyclonal rheumatoid factor (RF) preparations isolated from sera from various patients with rheumatoid arthritis (RA) were investigated with respect to their variable heavy chain (VH) subgroups. They were tested in a haemagglutination inhibition system using red cells sensitized with myeloma proteins with know... | 408,921 | [
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[Contribution to the radiation therapy of cerebral tumors (author's transl)]. | Postoperative radiation therapy chiefly has to be regarded under the aspects of prevention or delay of recurrences. Primary radiation therapy without surgical extirpation of the principal mass of the tumor generally represents a palliative measure. As the radiosensitivity of a cerebral tumor is not exclusively dependen... | 408,946 | [
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[Effectiveness of fenbendazole (Panacur) in cattle invaded by gastrointestinal and pulmonary nematodes]. | The effectiveness of the new anthelmintic fenbendazole (Panacur) produced by Hoechst, W. Germany, was tested in cattle naturally invaded by gastro-intestinal and pulmonary nematodes. The single dose of 5.7 mg per kg or 7.5 mg per kg body weight administered either in the form of a 10% suspension or in pellets containin... | 408,961 | [
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[Comparative characteristics of corticosteroid metabolism in lower simians and man]. | Corticosteroid metabolism has been investigated in Macaca mulatta, Papio hamadryas, Cercopithecus aethiops, Erithrocebus patas and man. Similar character of corticosteroid metabolism in monkeys and man was found. Significant interspecific differences with respect to quatitative and qualitative parameters of the metabol... | 409,003 | [
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Sensitization of stabilized fibrin to urea dispersion by undiluted plasma and serum. | Clots obtained from normal native platelet-poor plasma are dispersed by the addition of 5 M urea. Clots from plasma diluted greater than 1/4 and clots from undiluted plasma, thoroughly washed, are not dispersed by urea, but are rendered susceptible to its dispersing action by prior incubation in normal undiluted plasma... | 409,022 | [
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Binding of deoxyribonucleic acid to the surface of human platelets. | It was demonstrated that washed human platelets can bind minute amounts of 14C-DNA on their surface during short-term incubation. The binding was specific and firm in the described experimental conditions. Washed platelets bound also 14C-DNA anti-DNA antibody complexes, although to a lesser amount than 14C-DNA alone. T... | 409,023 | [
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Classic hemophilia A in a female. | A 53-year-old woman with a history of recurrent bleeding complications since childhood and a positive family bleeding history, previously diagnosed as von Willebrand's disease, was investigated. She was found to have a markedly reduced level of antihemophilic factor (AHF) activity, a low AHF activity/AHF antigen ratio,... | 409,025 | [
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Oral contraceptives, anti-thrombin III and fibrinolytic activity in Africans. | A comparison of the effects of progestogen-only and combined progestogen-oestrogen types of oral contraceptives on anti-thrombin III activity and fibrinolysis in African subjects in South Africa is reported. The changes in anti-thrombin III activity are similar to those reported in other races, but the augmentation of ... | 409,028 | [
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[Evolution of the adipose tissue during the postembryonic development in Coleoptera Catopidae. I. Studies in Choleva fagniezi and Speophyes lucidulus (author's transl)]. | Cytological studies of the fat body have been performed during the postembryonic development of 2 Coleoptera Catopidae: Choleva fagniezi and Speophyes lucidulus. As in other insects, the cells store large amounts of glycogen, lipids and proteins during the larval life; these reserves would be lysed and used during the ... | 409,039 | [
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X-ray microanalytical study of Mn and Fe compartmentation in maize chloroplasts. | X-ray microanalysis of mesophyll and bundle sheath maize chloroplasts showed that bound manganese is located within thylakoids, whereas bound iron is equally present in thylakoids and stroma. A simple correlation between manganese content and oxygen evolution capacity (Photosystem II activity) is unlikely since Mn is a... | 409,045 | [
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Tracheopathia chondro-osteoplastica. A clinical study of thirty cases. | During the last 12 years, 30 cases of tracheopathia chondro-osteoplastica have been diagnosed at the Department of Otolaryngology of Kuopio University. Ten of these were accidentally revealed by bronchoscopy, 2 by autopsy, but 18 were revealed through a systematic examination. Ten of these 18 were preliminarily diagnos... | 409,093 | [
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Severe radiation injuries of the lung. | The lung is a radiosensitive organ whose limited tolerance must be treated with great respect in the radiation management of malignant tumors in the thorax. Severe radiation pneumonopathy can cripple and kill as the outcome of faulty judgment, error, accident, or calculated risk in an effort to control a locally advanc... | 409,123 | [
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CT demonstration of the splenic vein-pancreatic relationship: the pseudodilated pancreatic duct. | Cross-sectional anatomy of the splenic vein-pancreatic relationship is reviewed and correlated with findings on computed tomography. A layer of fat which is normally present between the splenic vein and the pancreas may simulate a dilated pancreatic duct. Distinct demonstration of the splenic vein as a structure separa... | 409,134 | [
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Injuries of the medial epicondylar ossification center of the humerus. | The complex nature of the ossification centers makes elbow injuries in a child or adolescent difficult to evaluate. The medial epicondylar ossification center is involved in a significant proportion. Injuries vary from simple avulsions to wide displacement with entrapment in the elbow. When entrapment occurs, it may be... | 409,142 | [
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Utilization, reliability, and cost effectiveness of cranial computed tomography in evaluating pseudotumor cerebri. | Cranial computed tomography (CT) has reduced the frequency of cerebral angiography from 95% to 32% and pneumoencephalography from 71% to 11% in patients with pseudotumor cerebri. Total hospital stay has been significantly reduced from a mean of 19.6 to 13.3 days and the hospital days required for diagnosis from a mean ... | 409,161 | [
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Radiologic aspects of Beck gastric tube in esophageal reconstruction. | Over a 28 month period, 19 patients underwent esophageal reconstruction using the Beck tube fashioned from the greater curvature of the stomach. Eighteen had unresectable carcinoma of the esophagus and one had a benign stricture secondary to reflux esophagitis. The degree of palliation was considered good in 13 cases. ... | 409,195 | [
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Metrizamide myelography. | Complete myelography using metrizamide and a lumbar puncture is described with special emphasis on the cervical region. Good visualization of the cervical region was obtained in 19 of 20 patients using 10-12 ml and iodine concentrations of 250 mg/ml without special techniques or precautions. Possible explanations of fa... | 409,203 | [
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Avulsion of nerve rootlets with the Cuatico needle during Pantopaque removal after myelography. | Three cases of histologically proven nerve root avulsion during Pantopaque removal with a Cuatico needle are described. While use of such multihole needles poses some risk to patients, we feel the advantages outweigh the disadvantages, particularly when a large volume of Pantopaque has to be removed. To minimize the po... | 409,204 | [
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The practical use of thyroid function tests. | The diagnosis of thyroid disorders can usually be established by two tests: the serum T4 and the resin T3 uptake (RT3U). The T4 test measures both free and bound thyroxine; the RT3U reflects the number of binding sites available on thyroid-binding globulin. The values of these two tests can be used to calculate a free ... | 409,266 | [
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Pediatric nurse associates in a large official health agency: their education, training, productivity, and cost. | During 1974, 29 pediatric nurse associates and 15 pediatric nurse associate trainees worked in the child health care system of the New York City Department of Health. All of these nurse associates, formerly public health nurses from the Department of Health, were trained in a one-year, intensive, closely supervised did... | 409,303 | [
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The use of fluorescein angiography to study oxygen toxicity. | This study was designed to test whether oxygen toxicity results in retinal damage that could be documented by the technique of fluorescein angiography. Three squirrel monkeys lived in 100% oxygen environments for periods ranging from 50 to 117 hours. Two of the monkeys incurred damage as evidenced by early multifocal l... | 409,325 | [
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0.3140551,
0.002758717,
0.2376373,
-0.004436502,
0.4039179,
0.166677... |
In vitro activity of rosamicin against Neisseria and Haemophilus, including penicillinase-producing strains. | Rosamicin was significantly more active against Haemophilus and Neisseria than are many antibiotics currently used to treat or prevent infection caused by these organisms. This enhanced activity was also observed against penicillinase-producing strains. | 409,345 | [
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[Valve replacement in case of a partial atrioventricular canal. A propos of 17 cases]. | In 17 patients with a partial form of atrioventricular canal, at least one valve was replaced. The mitral valve was the most commonly affected (16 cases), sometimes in association with the tricuspid valve (5 cases) or the aortic valve (1 case); the tricuspid valve alone was replaced in one case. 7 cases were ranked as ... | 409,367 | [
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Optic disc edema in raised intracranial pressure. VI. Associated visual disturbances and their pathogenesis. | The pattern and pathogenesis of nonlocalizing visual disturbances, associated with optic disc edema (ODE). raised cerebrospinal fluid pressure, and intracranial space-taking lesions were investigated experimentally in rhesus monkeys with simulated progressive brain tumor and clinically in patients with benign intracran... | 409,382 | [
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[Characteristics of the interaction of 9,10-dimethyl-1,2-benzanthracene with the hairy cells in the central nervous system]. | The implantation of a pill containing carcinogen DMBA into the right hemisphere of the rat brain induces the formation of a capsule, the innermost layer of which is composed of "hairy" cells. Two principally different mechanisms of carcinogen penetration into the "hairy" cell were distinguished: ordinary phagocytosis a... | 409,443 | [
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0.0032... |
[Demonstration of 2 enzymes with beta-galactosidase activity in Rhizobium meliloti]. | The beta-galactosidase (EC 3.2.1.23) activities of wild-type Rhizobium meliloti and its lactose slow-hydrolyzing mutant have been compared. The properties of the enzyme are very different in each strain. These differences allow us to prove that two enzymes with a beta-galactosidase activity can be found in the wild-typ... | 409,467 | [
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Effect of somatostatin on thyrotropin, prolactin, growth hormone and insulin responses to thyrotropin releasing hormone and arginine in healthy, hypothyroid and acromegalic subjects. | The effect of somatostatin on the thyrotropin (TSH), prolactin, growth hormone (GH) and insulin responses to the combined administration of thyrotropin releasing hormone (TRH) and arginine was studied in six healthy subjects, three hypothyroid patients and three acromegalic patients. Similar inhibition by somatostatin ... | 409,475 | [
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Acute nonlymphocytic leukemia: a delayed complication of Hodgkin's disease therapy: analysis of 109 cases. | The use of combined modality therapy (irradiation and combinations of drugs) in the treatment of Hodgkin's disease has produced a significant improvement in survival, during which most patients lead an active and productive life. The estimated 1% incidence of leukemia in treated Hodgkin's disease patients, however, is ... | 409,479 | [
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Purification of some glycoside hydrolases by affinity chromatography. | Two glycoproteins have been isolated from the cell walls of baker's yeast. One is a glucan-protein complex which has been partially characterised as having a branched carbohydrate structure composed of chains of (1 leads to 3)-linked beta-D-glucosyl residues, some of which are attached by (1 leads to 6)-linkages to the... | 409,497 | [
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[Variation in the number and size of myelinated nerve fibers regenerated after repeated localized freezing of the sciatic nerve of rats]. | The number and size of myelinated fibres have been determined in the nerve to medial head of the gastrocnemius muscle of Rats in which the sciatic nerve had been frozen locally 1 to 5 times at monthly intervals. The contralateral nerve was used as a control. When the measurements were made one month after the last free... | 409,512 | [
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0.04... |
[Chronic hyperesthesia in rats caused by lesions in the dorsal roots of the branchial plexus]. | Traumatic avulsions of the brachial plexus in Man is followed by development of hyperesthesia which is known to be reistant to pharmacological medication. We have been able to reproduce this syndrome in the Rat and have used this disturbed animal as a model. This model will give us the possibility of studying nervous m... | 409,515 | [
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[The maternal protection reaction against a mother's rejection of her own larva in Salamandra salamandra L]. | In vitro experiments have shown that maternal spleen cells from Salamandra salamandra are cytotoxic to cells from their embryos. This reaction can be inhibited by maternal serum. In this paper, we show that maternal serum protection acts through two effects: by inactivating spleen cells and by protecting embryonic cell... | 409,525 | [
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[Morphologic alterations induced by aflatoxin B1 in Bacillus thuringiensis (Berliner)]. | Significative ultrastructural alterations shown in aflatoxin B1, treated cells of Bacillus thuringiensis are: increase of number of mesosomes which are hypertrophied, decrease of ribosomes and formation of imperfect cell septa. | 409,554 | [
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[5-hydroxytryptamine-sensitive adenylate cyclase activity in brain synaptosomal membrane preparations]. | A serotonine-sensitive adenylate cyclase system has been observed in horse brain membrane preparations. In crude mitochondrial fraction two types of activation sites were characterized, the Ka being = 2 nM and 1 micrometer. In purified synaptosomal membranes, a single adenylate cyclase activation was observed correspon... | 409,565 | [
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The combined clinical and hemodynamic effects of trinitrin and propranolol. | The clinical and hemodynamic effects of trinitrin (nitroglycerin) have been studied in 5 patients with long-established coronary artery disease who had been receiving long-term beta blockade therapy (propranolol). 5 similar patients not on propranolol acted as controls. Patients on propranolol reported as effective rel... | 409,604 | [
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[Metabolically adapted nutrition following the concept of clinical nutrition therapy--success and prospects]. | Modern dietetics abandon the traditional, mainly hypothetically based special types of nutrition. A better knowledge of the physiological and pathological metabolic reactions and the technical possibilities to produce defined, tailor-made dietetics products require a new way of thinking. It is attempted to establish a ... | 409,671 | [
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Bacterial adherence to nasal mucosal cells. | The ability of several bacterial species to adhere to human nasal mucosal cells and their distribution on nasal mucosal surfaces was studied. Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pyogenes, and Pseudomonas aeruginosa adhered to scraped nasal mucosal cells. In contrast, viridans streptococci a... | 409,676 | [
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Radiometric detection of carbohydrate catabolism by pathogenic Neisseria. | A liquid scintillation procedure for the catabolism of D-[1-14C]glucose and [U-14C]maltose by pathogenic Neisseria was tested. Definitive results were obtained within a 30-min incubation period. | 409,731 | [
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Hereditary C7 deficiency. Diagnosis and HLA studies in a French-Canadian family. | The serum of a 44-yr-old woman of French-Canadian descent having a B-27 positive ankylosing spondylitis was deficient in the seventh component of complement (C7) as determined by hemolytic and immunochemical methods. No inhibitor against C7 was detected, and the levels of all other complement components were normal. No... | 409,732 | [
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Complementary laminar terminations of afferents to area 17 originating in area 18 and in the lateral geniculate nucleus in squirrel monkey. | The projections from area 18 and the lateral geniculate nucleus onto area 17 of the squirrel monkey (Saimiri) were investigated with retrograde (horseradish peroxidase) and anterograde (tritiated proline) labelling techniques, and the (Fink-Heimer) silver impregnation method for degenerating axons and their terminals. ... | 409,740 | [
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Indium-111-labeled autologous leukocytes in man. | Autologous leukocytes have been isolated, labeled with indium-111, and administered to 15 patients suspected of inflammatory disease. The stability of the label has been demonstrated and the in vivo kinetics and distribution of the labeled cells studied. The distribution is influenced by the type and viability of the c... | 409,745 | [
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Incidence of IgG short-term sensitizing antibodies in an allergic population. | Heat-stable, immunoglobulin G, short-term sensitizing antibodies (IgG S-T S) were sought in serum from 149 allergic patients who had strongly positive immediate skin tests to inhalant allergens. The sera were tested by passive cutaneous anaphylaxis (PCA) in monkeys. No IgG S-T S antibodies were demonstrated in 169 test... | 409,752 | [
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Immunization with Shigella dysenteriae type 1: evaluation of antitoxic immunity in prevention of experimental disease in rhesus monkeys (Macaca mulatta). | The role of serum antitoxic antibody in protection against the dysentery caused by Shigella dysenteriae type 1 (Shiga's bacillus) was studied in monkeys fed 10(10) virulent organisms after parenteral immunization with a formalin-inactivated Shiga toxoid preparation standardized in mice. Two 125-microgram doses of toxoi... | 409,782 | [
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Application of the indirect enzyme-labeled antibody microtest to the detection and surveillance of animal diseases. | The rapid, indirect enzyme-labeled antibody (ELA) microplate test has been developed as a diagnostic and surveillance tool to aid in the control of animal disease. The test has been applied to viral (hog cholera), parasitic (trichinosis), and bacterial (brucellosis) diseases of animals. A correlation of greater than 95... | 409,789 | [
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... |
The ultrastructure of oral neuromas in multiple mucosal neuromas, pheochromocytoma, medullary thyroid carcinoma syndrome. | The ultrastructure of oral neuromas from 2 patients with multiple mucosal neuromas, pheochromocytoma, medullary thyroid carcinoma syndrome reveals numerous hypertrophic unmyelinated and myelinated axons, hyperplastic neurilemmal cells and associated collagen fiber formation. These tumors are described and compared ultr... | 409,817 | [
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0.038... |
Studies on the biology of the periodontium of marmosets. XIII. Histopathology of niacin deficiency stomatitis in the marmoset. | Adult cotton top marmosets made niacin deficient by long-term dietary deprivation, developed a syndrome characterized by anorexia, weight loss, weakness, diarrhea, dermatitis, enterocolitis and stomatitis. The stomatitis was highlighted by a necrotizing gingivitis and periodontitis and by an ulcerative and atrophic glo... | 409,831 | [
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Effect of colloidal association on the measured activity of alkylbenzyldimethylammonium chlorides against Pseudomonas aeruginosa. | The antibacterial activities of a homologous series (C8-C18) of alkylbenzyldimethylammonium cholorides (ABDAC) against Pseudomonas aeruginosa have been measured using both a minimum inhibitory concentration (MIC) procedure and a sterilization kinetics test carried out in deionized water. There was a log-linear relation... | 409,841 | [
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... |
Morphogenesis of bacteriophage phi 29 of Bacillus subtilis: mapping and functional analysis of the head fiber gene. | A set of mutants of Bacillus subtilis bacteriophage phi29 unable to synthesize the head fiber protein has been identified by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and autoradiography. Infectious phage are produced during restrictive infection. We have focused on mutant sus 8.5(900) because the mutat... | 409,854 | [
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... |
Breeding the owl monkey (Aotus trivirgatus) in a laboratory environment. | A breeding colony of owl monkeys (Aotus trivirgatus) established in 1972 produced 35 live infants during the first 3 years from an average daily population of 30 monogamous pairs. Initial productivity was poor, but once the breeding pairs were set up by karyotypes, reproductive performance improved. No seasonal influen... | 409,879 | [
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Behavioral research in breeding colonies of Old World monkeys. | The existence of an active behavioral research program using animals in primate breeding colonies was considered to be not only a compatable multiple use of animals, but a way of materially improving the management and efficiency of the breeding colonies. In colonies of monkeys specifically established for behavioral r... | 409,882 | [
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Factors influencing aggressive behavior and risk of trauma in the pigtail macaque (Macaca nemestrina). | Several experiments and surveys were conducted in a large colony of pigtail macaques (Macaca nemestrina) to determine some of the influences of spatial and social factors on aggressive behavior and risk of trauma. Female subjects exhibited more aggression when they had access to two-room suites than when they had acces... | 409,883 | [
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Antimicrobial lipids: natural and synthetic fatty acids and monoglycerides. | Over 40 natural or synthetic lipophilic compounds were screened for antimicrobial activity. Gram (+) bacteria and yeasts but not Gram (-) bacteria were affected by these agents. Epimino and selena fatty acids are more active than their corresponding straight chain unsubstituted fatty acids. The position of selenium inf... | 409,896 | [
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Use of a dynamic rangeshifter for modifying the depth-dose distributions of negative pions. | In order to use negative pions for the treatment of large deep-seated tumors in radiotherapy, it is necessary to produce depth-dose distributions tailored to specific shapes. We present here a method of beam shaping which utilizes a fluid-filled piston having a programmable, computer-controlled, time-dependent thicknes... | 409,920 | [
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0.035... |
[Recurrent retroperitoneal giant lipoma (author's transl)]. | A giant lipoma weighing 9.1 kg situated retroperitoneally which was removed by operation from a 74-year-old woman is reported. The diagnosis of tumors is discussed. The characteristics of this primary benign tumor such as the rapid growth, tendency to malignant degeneration and recurrence make radical surgical removal ... | 409,938 | [
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[Treatment of severe Rhesus erythroblastosis]. | Report about the management of cases of severe Rhesus erythroblastosis. One case is specially discussed because of it's actuality. This was a patient with severe Rh-sensitization (OOD at 450 mm from the beginning of the 30th week of gestation in zone III according to Liley). Because of the haemolytic disease and the ch... | 409,979 | [
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... |
Protein deprivation in primates: XII. food preferences of juvenile rhesus monkeys. | 21 male and 18 female juvenile rhesus monkeys whose mothers' prenatal diets varied according to protein content (either 1-, 2-, or 4-gm protein/kg body weight/day) were given a food-preference task. 20 monkeys were between 3 and 4 yr. old; 19 were between 1 1/2 and 2 1/2 yr. old. For each trial small pieces of the same... | 409,989 | [
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Further structural studies of the heavy chain of HLA antigens and its similarity to immunoglobulins. | The papain-solubilized fragment of the heavy chain of HLA-B7, which is the NH2-terminal part of the whole polypeptide chain, can be divided into three regions by mild acid and cyanogen bromide cleavages. The first 100 amino acids terminating in a methionine residue contain the carbohydrate moiety; this segment is follo... | 410,030 | [
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Reduced renal calcium excretion during lithium therapy. | The renal excretion of calcium was determined in ten subjects before and at intervals during 3 months of lithium treatment. The calcium excretion fell by more than 40% within the first week of treatment and remained low throughout the treatment period. The reduction in urinary calcium excretion could be accounted for b... | 410,054 | [
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... |
Effects on retention of posttraining amphetamine injections in mice: interaction with pretraining experience. | These experiments examined the effects of d-amphethamine on retention of one-trial inhibitory (passive) avoidance training in mice. Water-deprived mice were pretrained to lick from a water spout at the end of a darkened compartment. Footshock was administered during licking after 4, 6, or 7 days of pretraining. Retenti... | 410,056 | [
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The effects of methaqualone on the seizure susceptibility of mice. | Methaqualone produces dose- and time-dependent decreases in susceptibility to electrically, chemically, and sound-induced seizures. The antagonism of methaqualone to electroconvulsive shock can be dissociated from its effects on temperature regulation and plasma corticosterone. Studies with SKF525A, a drug known to blo... | 410,059 | [
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0... |
[Immunological defence mechanisms and inflammation (author's transl)]. | The interaction of immunological defence mechanisms and inflammation is reviewed. To begin with, those cells are discussed, which play a role in the immunological response, viz. the cells by which antigen is recognized (macrophages, B and T lymphocytes) and the effector cells (macrophages, plasma cells and sensitized T... | 410,115 | [
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Studies on Theileriidae (Sporozoa) in Tanzania. VIII. Experiments with African buffalo (Syncerus caffer). | It has been found that African buffalo may remain infective carriers of Theileria parva lawrencei for at least 5 years. This infection is now known to exist in buffalo in 3 sites in northern Tanzania. It was shown that buffalo can be infected with Haematoxenus veliferus and Theileria mutans of cattle and retransmission... | 410,128 | [
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[Clinical dosimetric studies of lung tissue heterogenetiy in irradiation on the Rokus and B5M-25 machines]. | As a result of measurements of radiation doses in the esophagus and of the emerging beam, which were made immediately during radiotherapy, the coefficients of heterogeneity and values of the effective lung density were determined. In mobile telegamma therapy of esophageal tumors the correction for heterogeneity was 1.2... | 410,160 | [
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... |
Experimental chemotherapy of schistosomiasis mansoni. XIII. Activity of praziquantel, an isoquinoline-pyrazino derivative, on mice, hamsters and Cebus monkeys. | In mice experimentally infected with Schistosoma mansoni, praziquantel (2-cyclohexylcarbonyl-1,3,4,6,7,11b-hexahydro-2H-pyrazino[2,1-a]isoquinoline-4-one), administered orally at the levels of 100 and 50 mg/kg, for 5 consecutive days, produces oogram changes in all animals and a pronounced hepatic shift of schistosomes... | 410,179 | [
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... |
Haemoglobin H disease and pregnancy in a Malaysian woman. | A case of haemoglobin H (HbH) disease associated with pregnancy is presented and discussed in the light of reports in the literature. The variable symptomatology is commented upon, although mild to moderate chronic haemolytic anaemia seems to be a constant feature. The roles of folic acid supplements and of splenectomy... | 410,224 | [
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Radiographic findings of immunoblastic lymphadenopathy and related immunoblastic proliferations. | Immunoblastic lymphadenopathy is a recently recognized disorder of unknown etiology accompanied by clinical manifestations similar to lymphoma. Radiographic examinations of nine patients revealed multisystemic involvement and findings similar to those of lymphomatous processes. The diagnosis of immunoblastic lymphadeno... | 410,254 | [
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... |
Strontium-87m lung scans in pulmonary aspergillosis. | Experimental observations have indicated that radioactive strontium localizes in lesions infected with Aspergillus species. Preliminary clinical studies have recommended use of strontium lung scanning to evaluate patients thought to have pulmonary manifestations of aspergillosis. In view of the difficulty in accurately... | 410,255 | [
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Acute erythroid hypoplasia in malnourished infant squirrel monkeys fed isolated soy protein. | Infant squirrel monkeys fed low protein diets using an isolated soy protein develop an acute anemia. To investigate this syndrome, four groups of animals fed diets containing adequate or restricted amounts of casein or soy protein were studied from 1 through 16 weeks of age. The low protein groups, in which growth was ... | 410,292 | [
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Histopathologic study of experimental Sarcocystis hemionilatrantis infection in fawns. | Mule deer fawns (Odocoileus hemionus hemionus) inoculated with sporocysts of Sarcocystis hemionilatrantis became infected, developed clinical signs of disease, and died, due to the infection itself or from intercurrent pneumonia. Clinical signs were first noticed 18 days after infection and fawns died from postinfectio... | 410,334 | [
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[2 new species of gregarines parasites of annelides: Pleurocystis eiseniellae of Eiseniella tetraedra Sav.)Oligochaeta), Pterospora petaloprocti of Petaloproctus terricola Quatr. (Polychaeta)]. | The first species belongs to the genus Pleurocystis (in the Oligocheta host, Eiseniella tetraedra). It is characterized by early syzygies with lateral connection and navicular sporocysts with similar poles. It differs from the only species already described of the genus and is named Pleurocystis eiseniellae n. sp. The ... | 410,353 | [
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Parathion utilization by bacterial symbionts in a chemostat. | A continuous-culture device was used to select and enrich for microorganisms, from sewage and agricultural runoff, that were capable of using the organophosphorus insecticide parathion as a sole growth substrate. Parathion was dissimilated by the highly acclimated symbiotic activities of Pseudomonas stutzeri, which non... | 410,368 | [
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... |
Effect of some bacterial products on platelet electrophoretic mobility (PEM). | Bacterial LPS, used in our experiments, are able to decrease PEM at concentration of 100 microgram/ml after incubation with 1 X 10(7) platelets/ml for 30 min at 37 degrees C. Such effect is statistically significant for Bacteroides fragilis LPS, S. enteritidis and S. typhi. E. coli LPS 026:B6 W and E. coli 055:B5 W are... | 410,424 | [
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0.3082711,
0.1888886,
0.04569558... |
[Effects of mutations in Bacillus subtilis genome decreasing the protease activity on the formation of subtilisin molecular forms]. | Multiple molecular forms of subtilisin--extracellular serine protease produced by the wild strain Bac. subtilis A-50 and its mutant strains with the protease activity decreased two-fold and more were studied. Six molecular forms of subtilisin were found on the whole when 33 mutant strains have been investigated under t... | 410,457 | [
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-... |
Histological observations on thymic development in fetal and newborn mammals subject to intrauterine growth retardation. | Fetal growth retardation resulting from maternal dietary protein deprivation (rats) or Coxsackie virus B3 infection in mid-pregnancy (mice) was associated with delayed thymic development. Histological examination revealed that less darkly staining small lymphocytes were present and that the thymus was not well organise... | 410,462 | [
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0.1250428,
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Development and significance of antibodies to salmon calcitonin in patients with Paget's disease on long-term treatment. | Sixteen consecutive patients in one unit were studied during long-term treatment of Paget's disease of bone with salmon calcitonin. Eleven patients developed detectable antibody titres at some time during treatment. In one patient with a high antibody titre evidence of resistance to treatment emerged two years after th... | 410,477 | [
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0.1522639,
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The stereochemistry of the addition of glycerol to D-galactal, catalyzed by beta-D-galactosidase. | On incubation with beta-D-galactosidase, D-galactal-2-d (1) plus glycerol yielded 1-deoxyglycerol-1-yl 2-deoxy-beta-D-lyxo-hexopyranoside-2(S)-d. By 1H-n.m.r. analysis, it was shown that the hydrogen atom introduced on C-2 is trans-related to the aglycon moiety. In contrast to this stereospecific, enzyme-catalyzed addi... | 410,500 | [
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0.1001085,
0.01233813,
0.2515953,
0.4568087,
0.205252,
-0.3460723,... |
[Presence of "pancreatic polypeptide" cells, and gastrin immunoreactivity in immuno-induced exocrine pancreas carcinoma]. | 1) In electively immuno-induced carcinomas of the exocrine pancrease in Mice, where A (glucagon) and B (insulin) endocrine cells persist, cells with a pancreatic polypeptide immunoreactivity are also detected, even in late evolution stages. These cells, like D cells, containing somatostatin, are localized only in the p... | 410,528 | [
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0.7615953,
0.1785838,
0.4281209,
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... |
[Development of plasma cortisol in calves from birth to 14 days of age]. | Plasma cortisol was recorded in 15 calves from birth to 14 days of age by a radio-immunoassay technique. At birth mean cortisol value is 67.3 ng/ml; 6 hrs. later it decreases by 58.4% then it gradually diminishes and about 14 days after, it reaches adult levels (5.1 ng/ml). | 410,536 | [
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0.1785996,
0.4193863,
0.36055,
0.07025929,
-0.07385467... |
[Kinetic study of carcinogenesis. The immune barrier and the stability of microcancer states]. | We show that cancerisation presents some similarities with first order phase transitions. We analyze the barrier opposed by cytoxic cells against the proliferation of cancer cells. | 410,554 | [
-0.05636887,
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[Isolation and description of a new species of Eimeria in rabbits (Orychtolagus cuniculus) : Eimeria pellerdyi P. Coudert, 1977 (Sporozoa, Coccidia)]. | Several pure isolates of Coccidia have been obtained in coccidia-free Rabbits by methods taking advantage of differences in the duration of their life-cycle and their site of development, as well as by the inoculation of experimentally immunized animals. Among these isolates one has been shown to represent a new specie... | 410,555 | [
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0.2977758,
0.2992195,
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0.1300004,
0.1042394,
... |
Experience with a low volume ultrafiltration cell in small children*. | A low volume (16 ml) ultrafiltration cell was used ten times in two small, fluid overloaded children to remove plasma water. The device was simple to use and, at slow blood flow rates (25-50 ml/minutes) and low transmembrane pressures (10-30 mm Hg), provided controlled removal of excess fluid. Although no major complic... | 410,570 | [
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0.087027,
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... |
Effect of thyrotropin releasing hormone on heart rate and visual evoked potentials in rats. | The effect of injection of 0.3 microgram of thyrotropin releasing hormone (TRH) into the third ventricle on heart rate and photically evoked potentials in the midbrain reticular formation in urethane-anesthetized rats was studied. TRH increased the heart rate and amplitude of the visual evoked potentials within a few m... | 410,635 | [
0.1148799,
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0.2590022,
0.3178951,
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... |
The shift-effect in the lateral geniculate body of the rhesus monkey. | Responses to sudden shifts of a pattern far away from the receptive field (shift-effect) were found in 73 out of 81 cells of the ventral, magnocellular LGN layers, but in only 26 out of 85 cells of the dorsal, parvocellular layers. Most of the former responses were clear and excitatory, and most of the latter were we... | 410,653 | [
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0.01614065,
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0.01551554,
0.2620707,
0.3961772,
0.1085747... |
Flexor tendon repair in "No Man's Land" an experimental study. | Twenty-five fingers of seven monkeys were used for an experimental study of a new concept of flexor tendon repair in "No Man's Land". Microsurgical aids were used to shift distally a sleeve of healthy flexor tendon sheath to cover the site of the repaired flexor tendon. There was a low success rate due to technical dif... | 410,703 | [
-0.2602037,
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0.1817674,
0.2976786,... |
Cranial and dental anomalies in three species of platyrrhine monkeys from Nicaragua. | This paper presents information on the cranial and dental anomalies observed in the crania of three species of platyrrhine monkeys collected in Nicaragua. Cranial anomalies that are discussed include plagiocephaly, bregmatic fontanelle bones, Wormian bones, cranial trauma, and heterotopic bones. Among the dental anomal... | 410,706 | [
-0.02992641,
0.1141621,
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0.004717393,
-0.2384053,
-0.1361444,
0.3492075,
0.01966326... |
You are dangerous to your health: the ideology and politics of victim blaming. | This article describes the emergence of an ideology which blames the individual for her or his illness and proposes that, instead of relying on costly and inefficient medical services, the individual should take more responsibility for her or his health. At-risk behavior is seen as the problem and changing life-style, ... | 410,739 | [
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0.1736624,
0.3856035,
-0.0686... |
Use of argA-lac fusions to generate lambda argA-lac bacteriophages and to determine the direction of argA transcription in Escherichia coli. | Fusions of lac genes to the argA operator were constructed, and lambda phages carrying these fusions were isolated and characterized. With the aid of a lambda phage carrying an argA-lac fusion, the direction of argA transcription on the Escherichia coli chromosome was determined to be clockwise. | 410,785 | [
-0.01143759,
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-0.2810104,
0.5157386,
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-0.01629... |
Chemotaxis by Bdellovibrio bacteriovorus toward prey. | A chemotaxis assay system that uses a modified Boyden chamber was characterized and used for measurements of chemotaxis by Bdellovibrio bacteriovorus strain UKi2 toward several bacterial species. Bacteria tested included both susceptible and nonsusceptible cells (Escherichia coli, Pseudomonas fluorescens, Bacillus mega... | 410,796 | [
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0.4220754,
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0.2664434,
... |
Hydroxylaminolysis of penicillin binding componenets is enzymatically catalyzed. | The hydroxylaminolysis of the penicilloyl moiety from [14C]penicillin G binding component (PBC) complexes of the Bacillus subtilis D-alanine carboxypeptidase and of the mixture of PBC's of Staphylococcus aureus was inhibited by denaturation of the complexes by heat (55 degrees), detergent (1% sodium dodecyl sulfate), o... | 410,805 | [
0.3074298,
0.061217,
0.05232117,
0.3597099,
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0.2395925,
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0.04200015,
0.04824286,
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0.3499084,
0.4854725,
0.4597053,
0.04585844,
-0.06798668,
-0.096... |
Preliminary crystallographic investigations of two phycobiliproteins. | Single crystal x-ray diffraction investigations are in progress on two phycobiliproteins. C-phycocyanin from Anabaena variabilis crystallizes in space group P63 with a = b = 154 A and c = 40 A. The crystallographic asymmetric unit is (alphabeta)2 with a total molecular mass of 7.0-10(4) daltons. B-phycoerythrin from Po... | 410,813 | [
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0.1188351,
0.00756223,
0.3162488,
0.2925507,
-0.0991... |
Effects of CNS dopamine augmentation on stimulated prolactin secretion. | The site, hypothalamic and/or pituitary, for dopaminergic inhibition of prolactin (PRL) secretion is unknown. Consequently, the effect of central dopamine (DA) augmentation on stimulated PRL release was determined in 5 healthy men. Regular insulin (o.1 U/kg i.v.), a potent central stimulus for PRL secretion, and TRH, a... | 410,827 | [
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0.08287014,
-0.2188942,
0.2301692,
-0.04244486,
0.143516,
0.08622605... |
Isolation of Streptococcus equinus from non-respiratory sources in children. | Streptococcus equinus, a non-enterococcal streptococcus, was isolated with increased frequency in a pediatric population. | 410,829 | [
-0.1819228,
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Generation of the combined prothrombin activation peptide (F1-2) during the clotting of blood and plasma. | We have investigated the pathway of prothrombin activation in blood and plasma. By means of a rapid purification procedure involving chromatography on DEAE-cellulose and hydroxyapatite, we demonstrated that the major prothrombin fragment in serum is that representing the amino-terminal half of prothrombin (i.e. F1-2). ... | 410,831 | [
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0.02390269,
0.1079343,
0.2141302,
0.6083118,
0.1517138,
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-0.... |
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