title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Distribution of indigenous Lactobacilli in the digestive tract of conventional and gnotobiotic rats. | Distribution of indigenous lactobacilli in the gastrointestinal tracts of rats was investigated at the species level. The indigenous lactobacilli isolated from conventional rats were divided into three groups, Lactobacillus acidophilus and its related strains, L. fermentum, and L. murini. Localization of the Lactobacil... | 406,500 | [
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Peripheral uveitis in the owl monkey. Experimental model. | Primary intravitreous HA injections cause a great variation in ocular inflammatory response, ranging from slight Tyndall effect (LI-HA) to severe inflammation (HI-HA). Both slight and severe inflammation are transient and subside completely within 10-30 days (early inflammatory response), whereas multiple injections ( ... | 406,519 | [
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[Traffic accidents in childhood--an analysis of 4100 cases (author's transl)]. | Every hour a child dies as a result of an accident. Most accidents to children occur between 10.00 and 12.00 in the morning and between 15.00 and 17.00 in the afternoon. 2-6 year-old children are particularly liable to accidents. They make up 50% of all accidents to children. 20% of all accidents occur in traffic; in t... | 406,530 | [
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[Operation for draining the stomach by subtotal pyloro-myectomy with and without dilatation of the mucous membrane (author's transl)]. | According to our experiences a pyloroplasty adequate in shape and function can be formed by a separate plastic surgical treatment of the serosa muscularis and mucosa, which can not only be carried out in a very simple way, but if strict attention is paid to its indications and the technical details are adhered to exact... | 406,532 | [
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[Therapy of malignant tumors of the thyroid]. | Early detection is still the most urgent concern for the successful treatment of carcinoma of the thyroid. A considerable obstruction to early tumor recognition in Germany is the still much too frequently recorded "endemic goiter". A consistent general goiter prophylaxis by iodization of the domestic salt may also have... | 406,538 | [
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[Treatment of breast cancer (author's transl)]. | Controlled trials and long term studies in patients with breast cancer of stage I and II have shown, that this disease in the majority of cases is no longer localized when first noticed clinically. Surgical therapy is therefore only a part of the complete management of these patients and must be thought over concerning... | 406,539 | [
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[The hemophiliac as a surgical patient (author's transl)]. | In the Surgical Clinic of the University of Munich, 23 surgical interventions were performed on 20 hemophiliac patients between 1967 and 1976. There were 13 emergency and 10 elective operations. The spectrum ranged from removal of atheroma to subtotal gastric resection. For adequate substitution of factors a comprehens... | 406,551 | [
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Effect of maternal protein deprivation on the development of neonatal intestinal function in rats. | The developmental pattern of in vitro intracellular accumulation (IA) was studied in the small intestine of the offspring of females fed a 27% protein diet (normal) (NPD animals) and the offspring of females fed an 8% protein diet (low) (LPD animals). At 2 days of age, the IA of L-leucine (Leu) and D-galactose (Gal) wa... | 406,591 | [
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Pattern structure and relational discrimination learning. | McGonigle and Jones take exception to Dodwell's explanation of anomalous transfer (AT) as the outcome of relational discriminations among a set of stimulus patterns which vary along a single dimension of orientational salience, from 'horizontal' to 'vertical'. In particular they do not think that the continuum is gener... | 406,595 | [
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Effects of cigarette smoking on incidental memory. | The effects of cigarette-smoking in an immediate memory task were studied in two groups of 25 female students (habitual smokers) tested either under a control (no smoking) condition or after smoking one cigarette. The memory task, requiring immediate serial recall of eight words, showed no differences between the two g... | 406,623 | [
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Effects of exposure to lead on social behaviour in the laboratory mouse. | Ethological analysis has been employed to study the behavioural effects produced by exposure of mice to lead salts from infancy. Mother mice of the treated group received 0.1% lead acetate as their sole drinking fluid within 24 h after the birth of their litters and the offspring received this fluid from weaning. At 8 ... | 406,631 | [
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Prenatal alcohol consumption and open-field behaviour in rats: effects of age at time of testing. | Throughout gestation pregnant Wistar rats consumed a nutritious liquid diet containing 35% ethanol-derived calories. Control mothers were fed lab-chow. Subsequently, the offspring of the ethanol-fed mothers displayed significantly greater activity (ambulation) in an open-field test at 28 and at 56 days of age, but not ... | 406,636 | [
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Physical aspects of electron-beam arc therapy. | The effect of different parameters on dose distribution in electron-beam arc therapy was studied in order to develop a technique for routine clinical use. A special diaphragm was designed to facilitate telecentric rotation. Dosimetry was performed with an ion chamber, film, and LiF powder in cylindrical polystyrene pha... | 406,643 | [
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Neurohistological observations on the tongue of the tufted capuchin, Cebus apella Linnaeus, 1758. | Neurohistological observations of the tongues of the adult monkeys Cebus apella are described. It was noted that the Cebus tongue presents few vallate papilae situated mainly in the posterior and lateral parts; fungi and filiforms are spread all over the dorsal surface. Histologically there was evidence that numerous n... | 406,648 | [
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Further studies on the ridge at the internal edge of the cataract incision. | A pathologic and experimental study of the etiology and morphology of the ridge, visible gonioscopically in the region of the internal lips of the cataract incision during and after the cataract operation, is described. The ridge observed clinically cannot be reproduced in human eye-banks eyes but can be reproduced in ... | 406,708 | [
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The use of echocardiography in determination of reversible posterior wall asynergy. | Recent studies have indicated that nitroglycerin can be delineate potentially reversible asynergic zones depicted ventriculographically. To assess the ability of the echocardiogram to detect reversible asynergy, posterior wall motion was assessed in 19 patients both echocardiographically and ventriculographically befor... | 406,768 | [
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The lack of specificity of the sheep erythrocyte-T lymphocyte rosetting phenomenon. | One subpopulation of lymphocytes, thymus-derived (T) cells, is identified by its characteristic ability to form spontaneous rosettes with sheep erythrocytes (SRBC). However, the mechanism by which the rosettes form remains unknown. To gain more insight into the specificity of this phenomenon, the ability of SRBC to ros... | 406,792 | [
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Activities of various 4-aminoquinolines against infections with chloroquine-resistant strains of Plasmodium falciparum. | The studies reported here stemmed from a personal report by Geiman on the capacity of the 4-aminoquinoline amodiaquin to inhibit in vitro maturation of ring stages of the chloroquine-resistant Monterey strain of Plasmodium falciparum. This observation, confirmed in owl monkeys infected with this strain, led to a compar... | 406,829 | [
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Five-hour minimal inhibitory concentration test of four antimicrobial agents for Pseudomonas aeruginosa. | A rapid 5-h minimal inhibitory concentration procedure and a minimal bactericidal concentration procedure are described for testing Pseudomonas aeruginosa against gentamicin, tobramycin, amikacin, and carbenicillin. The rapid test results were demonstrated to correlate with the conventional tube dilution procedure. | 406,835 | [
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Pharmacological prophylaxis in the kindling model of epilepsy. | Review of antiepileptic drug assessment to date by means of the kindling model of epilepsy suggests that it fills a gap that is evident in standard screening methods such as maximum electroshock or pentylenetetrazol screening tests. However, in order to obtain a comprehensive profile of antiepileptic drugs regarding pr... | 406,881 | [
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Transcriptional changes in pupal hypoderm in Drosophia melanogaster. | Transcriptional changes with development of the imaginal thoracic hypoderm of Drosophila melanogaster were evaluated by studies on pulse labeling and total composition with respect to protein. Evidence presented indicates that certain glycoproteins produced by prepupal salivary glands are important for bristle developm... | 406,897 | [
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High-sensitivity sequence analysis of peptides and proteins by 4-NN-dimethylaminoazobenzene 4'-isothiocyanate. | A manual high-sensitivity sequencing method is described, in which 4-NN-dimethylaminoazobenzene 4'-isothiocyanate is used for the stepwise degradation of amino acid residues from the peptides. The 4-NN-dimethylaminoazobenzene 4'-thiazolinones of amino acids that were released, after conversion into their thiohydantoin ... | 406,900 | [
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Separation and properties of two arylamidases from rat cardiac-muscle extracts. | Two main arylamidase activities were separated from a particle-free supernatant of rat heart by chromatography on DEAE-Sephadex. Although both enzymes hydrolysed L-leucine 4-nitroanilide, only peak-II enzyme hydrolysed L-lysine 4-nitroanilide. A third minor peak (Ia) contained an enzyme that was active mainly on the L-... | 406,901 | [
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Vitamin A receptors. I. Comparison of retinol binding to serum retinol-binding protein and to tissue receptors in chick retina and pigment epithelium. | 1. A simple, efficient three-step method for purification of serum retinol-binding-protein is described with homogeneity obtained after chromatography on DEAE-Sephadex, CM-Sephadex and Sephadex G-100. 2. Evidence is presented indicating that retinol receptors present in the cytosol fraction of chick retina and pigment ... | 406,937 | [
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Oxidant effect of acetylphenylhydrazine: a comparative study with erythrocytes of several animal species. | Red cells from several animal species were treated with acetylphenylhydrazine and a comparative study of the oxidation of hemoglobin (Hb) and glutathione (GSH) made. Wide interspecies differences were observed but the oxidation of GSH paralleled that of Hb. Added glucose protected both Hb and GSH from oxidation; GSH by... | 406,973 | [
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Detection and microbiologic assays of antimetabolites. | The biochemical considerations applicable in the detection of new antimetabolites are very similar to those used in developing microbiologic assays for these drugs. An in vitro system for detection of antimetabolites was developed based on different sensitivities to such drugs of bacteria cultivated in complex versus c... | 406,992 | [
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Strand breaks of mammalian mitochondrial DNA induced by carcinogens. | Closed circular mitochondrial DNA in mammalian cells was degradated to the open circular form by exposure of the cells to the carcinogens N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and 4-nitroquinoline 1-oxide (4NQO). MNNG caused more strand scission of mitochondrial DNA than 4NQO at the same concentration. The action... | 407,011 | [
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Analogues of hexamethylmelamine. The anti-neoplastic activity of derivatives with enhanced water solubility. | The preparation of some water soluble analogues of the tumour growth inhibitory hexamethylmelamine is described. The ultra-violet absorption characteristics, solubility and n-octanol/water partition coefficients of these new derivatives and some related compounds have been determined. Rates of demethylation by a liver ... | 407,012 | [
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0.35923,
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0.20066,
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0.0... |
[Study of marine microvibrios of Roscoff (Microvibrio marinus roscoffensis)]. | Marine microvibrios, predators of E. coli, have been detected worldwide, from equatorial waters to the polar regions. The morphology and behavior of two microvibrios have been studied. Their multiplication and aggressiveness in regard to their bacterial prevy are not impeded by dialysis membranes and manifest themselve... | 407,028 | [
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Determination of plasma 3-methoxy-4-hydroxyphenyl-glycol by pulsed electron capture gas chromatography. | An improved method is described for determining picogram quantities of 3-methoxy-4-hydroxyphenylglycol (MHPG) in plasma of humans and of other species. The method makes use of gas-liquid chromatography and electron capture detection. Low level nonlinearity of detector response was corrected by operating the detector in... | 407,037 | [
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The action of lysozyme on peptidoglycan with N-unsubstituted glucosamine residues. Isolation of glycan fragments and their susceptibility to lysozyme. | 1. A peptidoglycan preparation N-acetylated at about 30% of glucosamine residues was obtained by the treatment of the lysozyme-resistant cell wall paptidoglycan of Bacillus cereus with acetic anhydride at pH 7. Fractionation of dialyzable material resulting from lysozyme digestion of the glycan component of this peptid... | 407,083 | [
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[Inferotemporal cortex and short term visual memory in monkeys. New data]. | The effects of bilateral electrical stimulation of inferotemporal cotex on matching to sample were studied in four monkeys. Each session was defined by four different factors. 1. Number of stimuli: the same pair of stimuli (one-pair condition, OP) or a different pair of stimuli (multi-pair condition, MP) was used, from... | 407,096 | [
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0.2945603,
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Linkage disequilibrium in natural populations of Drosophila melanogaster Seasonal variation. | Linkage disequilibrium among ten polymorphic allozyme loci and polymorphic inversions on chromosomes 2 and 3 in a natural population of Drosophila melanogaster was examined early and late in the annual season. Similar to previous studies, little linkage disequilibrium was observed among allozymes. The two significant c... | 407,131 | [
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Ontogeny of the ectotympanic-petrosal plate relationship in strepsirhine prosimians. | The two major groups of living strepsirhine prosimians (the lorises and lemurs) display two different forms of the ectotympanic-petrosal plate relationship (EPPR). Ontogenetically, the factors producing this difference primarily relate to (1) the degree of elaboration of the sutural tissues at the ectotympanic-petrosal... | 407,138 | [
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[Long-term treatment with anticonvulsants in childhood. Guidelines for the practice]. | Long-term treatment with antiepileptic drugs is based on a differentiated diagnosis. Medication appropriate for a special type of seizures has to be chosen. Treatment must be controlled carefully to avoid side effects. Total blood count, urinalysis and determination of enzymes (alkaline phosphatase etc.) are necessary ... | 407,140 | [
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Appearance of a variant of MOPC 104E which does not react with dextran B-1355s. | MOPC 104E is a mouse plasmacytoma which produces an IgM (lambda) myeloma protein. This IgM protein has a binding specificity for dextran B-135s. This report describes a variant of the MOPC 104E tumor which secretes a myeloma protein which does not react with the dextran. The apparent variant of MOPC 104E arose spontane... | 407,151 | [
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A putatively new antigen (CSAp) associated with gastrointestinal and ovarian neoplasia. | CSAp is an antigen originally identified in the GW-39 human colonic carcinoma xenograft, and also found in gastric and colonic cancers, fetal colon, normal and inflammatory adult colon, and in some ovarian tumors. However, it appears to be increased primarily in inflammatory, benign , malignant, and fetal human intesti... | 407,152 | [
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Production of copper coproporphyrin III by Bacillus cereus. II. Regulation of the biosynthesis of coproporphyrin III and its copper complex by oxygen and heavy metal ions. | The effects of oxygen and heavy metal ions on the production of copper coproporphyrin III were studied in Bacillus cereus strain 2. The formation of copper coproporphyrin III was found to be maximum when the cells were cultivated in G-medium at a low level of oxygen supply, but it was suppressed at extremely low oxygen... | 407,222 | [
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Separation of pathogenic from apathogenic Listeria monocytogenes by three in vitro reactions. | One-hundred-twelve isolants of Listeria monocytogenes cultured from clinical and nonclinical sources were examined for hemolytic activity by means of the CAMP phenomenon and tested for acidification of xylose and rhamnose. The reactions of the isolants were noted and correlated with the pathogenicity of the organisms. ... | 407,244 | [
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Automated, rapid identification of bacteria by pattern analysis of growth inhibition profiles obtained with Autobac 1. | A scheme for identifying bacteria has been devised which utilizes the inhibition patterns obtained by Autobac 1 with routine and unusual antimicrobial agents and with other differentially inhibitory chemical compounds. Over 600 compounds were initially identified from the literature, and over 125 of these were selected... | 407,248 | [
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Ultrasonographic assessment of neck masses. | Fourteen patients are presented to illustrate the usefulness of ultrasonography in assessing masses of the neck. Included are five patients with primary tumors, two with metastasis to a cervical node, three with cervical adenitis, two with simple cysts, and two with hematoma related to endarterectomy for occlusive dise... | 407,254 | [
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Aspects of the humoral response to laboratory white mice infected with the metacestodes of Taenia crassiceps. | Two strains of laboratory white mice, CFLP and LACA, were infected with the metacestodes of Taenia crassiceps. The serum from each infected mouse was tested for antibodies on double-diffusion gel plates and the number of antigen-antibody precipitin lines formed related (a) to the duration of the infection and (b) to th... | 407,275 | [
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Developmental effects of X-irradiation of early Drosophila embryos. | Drosophila embryos were treated at specific stages during early embryogenesis with various doses of X-irradiation. The lethality at various times during development was established and pattern defects in the adults noted. It was observed that the most sensitive stages of embryogenesis to X-ray-induced lethality were al... | 407,324 | [
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Action of vasopressin, ouabain, and cyanide on the volume of isolated toad bladder epithelial cells. | Toad bladder epithelial cells were isolated under mild conditions in a calcium-free medium; they were found to exclude trypan blue, to consume oxygen, and to respond to vasopressin with an increased rate of oxygen consumption. Since isolated toad bladder epithelial cells are mostly spherical in shape, the cell diameter... | 407,362 | [
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Distribution of Mason-Pfizer virus-specific sequences in the DNA of primates. | Iodinated Mason-Pfizer virus (MPV) 60-70S RNA has been used in molecular hybridization experiments to determine the distribution of MPV-specific proviral sequences in the DNAs of primates. Approximately 20% of the MPV genome is present as endogenous provirus in rhesus monkeys. Competitive hybridization experiments show... | 407,372 | [
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Respiratory pathogens in non-human primates with special reference to Corynebacterium ulcerans. | An investigation of 272 non-human primates (75 Macacca cynomolgus, 97 Macacca mulatta and 100 Cercopithecus aethiops) revealed a high incidence of respiratory disease caused by Corynebacterium ulcerans, Staphylococci, Diplococci and Streptococci. Escherichia coli was also found as a secondary invader. Most of the infec... | 407,395 | [
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The anticonvulsant action of sodium valproate (Epilim) in 100 patients with various forms of epilepsy. | Sodium valproate (Epilim) has been used in the management of 100 patients with previously uncontrolled epilepsy for periods up to 2 years. If all manifestations of epilepsy are considered together, 75% to 100% control of seizures was achieved in 43% of patients, 25% to 74% control in 26%, and no improvement occurred in... | 407,431 | [
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DNA repair in Bacillus subtilis. I. The presence of an inducible system. | Following UV irradiation of Bacillus subtilis there is a coordinate induction of: 1) a new protein, 2) a W-reactivation system, 3) a DNA modification system, and 4) prophages. These functions are induced following UV irradiation of repair proficient bacteria and mutants deficient in excision repair (UVR-1) and DNA poly... | 407,445 | [
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Patient care and family counseling. Social work considerations in audits of hyperkinetic reaction of childhood. | To assure optimal patient care, a multidisciplinary audit of hyperkinetic reaction of childhood should involve the social work department. Specific process criteria can be established to assess the psychosocial evaluation of the patient, inpatient social work treatment, and follow-up care. Collectively, these criteria ... | 407,536 | [
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Maternal behavior: a determinant of amphetamine toxicity in rats. | At 130 days of age, 31 female rats that had been subjected in infancy to handling, mother-separation, both, or neither, were injected with d-amphetamine (100 mg/kg, 50 mg/ml, i.p.). The subjects form handled, mother-present litters were the only group that showed increased latency to death. This finding indicated that ... | 407,601 | [
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Sensitization to cocaine stimulation in mice. | Repeated administration of cocaine to B6AF1/J mice increased their running response to 20 mg/kg cocaine as much as four-fold over the response to the first injection. After four daily injections, the extent of the increase was proportional to the dose of cocaine that was used for pretreatment. Sensitization persisted f... | 407,604 | [
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Antibiotic resistance transfer from nonpathogenic to pathogenic bacteria. | Alcaligenes species is a common contaminant of "wet" environmental areas on the surgical ward. Although thought to be a nonpathogenic organism, recent clinical experience on the burn and trauma service has led us to believe that antibiotic resistance transfer may occur between Alcaligenes and Pseudomonas aeruginosa. To... | 407,662 | [
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[Radiographic findings in Rhesus monkeys experimentally infected with African lung flukes (Paragonimus africanus and P. uterobilateralis) (author's transl)]. | The radiographic pattern in the course of experimentally infected Rhesus monkeys with the two African fluke species Paragonimus africanus and P. uterobilateralis consist of hilar dilatation, streaky, patchy or diffuse shadows, cavities, atelectases and pleural reactions. All animals develop changes in both lungs, those... | 407,680 | [
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[Chromosomes of 3 lymphoblastoid suspension cell lines obtained from baboons with malignant lymphoma]. | Three suspension cell lines from bone marrow (BMPH-1) and spleens (SPH-2 and SPH-3) of hamadryas baboons with haematosarcoma were presented by analogous lymphoid type cells of a high proliferative activity. The modal class of cells in all the three lines was presented by diploids and pseudodiploids, though there was a ... | 407,685 | [
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An epizootic among knots (Calidris canutus) in Florida. II. Ultrastructure of the causative agent, a Besnoitia-like organism. | Multinucleated cysts near the luminal surface of the thoracic aortas of diseased knots (Calidris canutus) were similar to besnoitia cysts. Ultrastructurally, the cyst had four distinct layers. The central area included a vacuole that contained a sporozoan with a conoid, polar ring, micronemes, rhoptries, nucleus, mitoc... | 407,700 | [
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-0.06503341,
... |
Further observations on the preparation of antiglobulin reagents reacting with c3d and c4d on red cells. | A simplified method was developed for preparing rabbit red cells coated only with human C3d by the alternative pathway; these cells were injected into the donor rabbit to prepare an anti-C3d serum. Monkey red cells were sucessfully coated with human C4d, using a low-ionic-strength method, and these cells were injected ... | 407,724 | [
-0.2493902,
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0.0390099,
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0.1528777,
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... |
Circadian variations in microsomal drug-metabolizing enzyme activities in rat and rabbit tissues. | 1. The circadian variations in drug-metabolizing enzyme activities have been measured in microsomal fractions from the livers, lungs, and intestines of rabbits and in the livers and intestines of rats. 2. Circadian rhythms in enzyme activities in the rat intestine show 2 peaks in activity (around 0500 and 1900 h) with ... | 407,730 | [
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0.1396131,
0.1143621,
0.2085385,
0.1251248,
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Effect of prolonged oral administration of TRH on plasma levels of thyrotrophin and prolactin in normal individuals and in patients with primary hypothyroidism. | Forty mg TRH/day was given orally for 3 weeks to 10 euthyroid women and 10 women with primary hypothyroidism on low replacement doses of thyroxine. Once weekly oral TRH was replaced by an iv TRH-test (0.4 mg) with measurement of serum concentration of TSH, prolactin (PRL), thyroxine (T4), triiodothyronine (T3) and chol... | 407,759 | [
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0.2260635,
0.0110534,
0.6462613,
0.0839118,
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Glycogen synthetase and phosphorylase activity in slow and fast twitch skeletal muscle fibres in man. | Glycogen synthetase (I + D) and phosphorylase (à + b) activity was determined in human skeletal muscle biopsies with different muscle fibre composition and in dissected an pooled batches of the two main muscle fibre types: slow twitch (ST) and fast twitch (FT), respectively. Glycogen synthetase (I + D) activity remain... | 407,776 | [
0.06154682,
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0.31705,
0.2701556,
0.2608451,
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... |
Condylar translation and the function of the superficial masseter muscle in the rhesus monkey (M. mulatta). | The relationship between translation of the mandibular condyle during symmetrical mandibular rotation, i.e., symmetrical jaw depression and elevation, and the function of the superficial masseter muscle was examined in light of relative torque and the length-tension relationship for muscle. Lateral cephalograms of live... | 407,804 | [
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Demonstration of organ-characteristic glycoproteins in human semen. | Tridacnin M, a galactosyl-specific reagent prepared from the bivalve clam Tridacna maxima (Röding) was used for the demonstration of 2 different glycosubstances with terminal galactosido units in human semen. The results obtained by immunodiffusion tests indicate that the seminal plasma contains a water-soluble glycopr... | 407,814 | [
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0... |
[Lysis of bacterial protoplasts and spheroplasts and suppression of their dehydrogenase activity by neotehomycin]. | Neotelomycin induced lysis of the protoplasts of Bac. megaterium and inhibited their succinate dehydrogenase activity. Direct correlation between the lytic activity of the antibiotic and its effect on succinate dehydrogenase was found. Neotelomycin had no effect on the dehydrogenase activity of the protoplast lysates. ... | 407,837 | [
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Postoperative nutritional support using needle catheter feeding jejunostomy. | Needle catheter jejunostomy was used as an adjunctive surgical procedure in 110 patients. In 19 patients (or 17%) the jejunostomy was of value for the administration of post-operative nutritional support using an elemental diet and it may serve as an alternative route for the administration of supplementing fluids and ... | 407,853 | [
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... |
[Spontaneous and post-surgical outcome of incomplete forms of atrio-ventricular canal]. | 125 patients with an incomplete type of atrioventricular canal defect (AVC) were followed up over a very long period. A study of the changes in parameters which are not open to great variability has allowed a more precise approach to the spontaneous and postoperative course of this congenital cardiac defect. The fact t... | 407,867 | [
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0.4... |
Sensitivity of various human lymphoblastoid cells to the antiviral and anticellular activity of human leukocyte interferon. | Of eight lymphoblastoid cell lines studied five were insensitive to both the anticellular and antiviral activities of human leukocyte interferon, and two were sensitive to both activities. One line could not be fully evaluated since it was not possible to study its sensitivity to the antiviral activity. | 407,887 | [
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The biosynthesis of tyramine glucuronide by liver microsomal fractions. | Labelled tyramine glucuronide was synthesized in vitro from UDP-[14C]glucuronic acid, [14C]tyramine or [3H]tyramine. The glucuronidation was carried out at pH9.2 in the presence of a monoamine oxidase inhibitor, trans-2-phenylcyclopropylamine. The Km values for tyramine were 69 and 125 micrometer and those for UDP-gluc... | 407,904 | [
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0.3329899,
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[Petit mal status]. | The historical evolution of P.M.S. nosography is pointed out, and his clinical features are exposed, mainly on the ground of the study performed by Lob and Coll., for the Tenth Marseilled Colloquium. Stress is laid upon the onset age of P.M.S., making reference to a review of 133 cases previously reported in the litera... | 407,912 | [
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0.037791,
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Pulsating enophthalmos and choroidal hamartomas: two rare stigmata of neurofibromatosis. | A young girl with neurofibromatosis demonstrated two rare stigmata of this disease--pulsating enophthalmos and multiple pigmented choroidal hamartomata. Fundus photographs of the latter are believed to be the first of their kind to be published. | 407,919 | [
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Haloperidol-induced dyskinesias in the monkey. | Haloperidol (0.25 mg/kg i.m.) was injected daily for 6 months in six normal monkeys. Over a 24 hour period, the following symptoms could be observed: akathisia, circling, akinesia, choreoathetoid and dystonic movements, oro-facial dyskinesias and postural tremor with or without harmaline. Six months after cessation of ... | 407,996 | [
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Ribonuclease activity in plasma and leucocytes of malnourished children. | RNAase activity was measured in plasma and leucocytes of manourished children. In subjects suffering from kwashiorkor, alk. RNAase levels in plasma and leucocytes were markedly raised and they returned to normal after therapy. However, the enzyme activity was not altered in undernourished children. These data indicate ... | 408,059 | [
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0.2466657,
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-0.091... |
Thyrotrophin releasing hormone--TSH. | The major determinant of serum TSH and its response to TRH is the interaction of TRH and the thyroid hormones (principally T3) at the level of the thyrotroph. Small changes in thyroid hormone levels within the normal range can produce marked alteration in thyrotroph sensitivity to TRH. Elevated serum TSH is of great di... | 408,066 | [
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... |
Positive inotropic action of glyceryl trinitrate as observed in the blood-perfused papillary muscle preparation of the dog heart. | 1. The effects of glyceryl trinitrate on the coronary vasculature and on the contractility of the ventricular myocardium were investigated by the use of papillary muscle preparations of the dog, and that on the sino-atrial node activity by the use of sino-atrial node preparations of the dog. The papillary muscle prepar... | 408,068 | [
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[Oral iron treatment: intestinal absorption and the influence of a meal (author's transl)]. | Intestinal iron absorption after a single dose of a special galenic preparation (50 and 100 mg iron as ferrous glycocoll sulphate in micropellets) was investigated in 105 persons with normal iron stores (42), latent (40) or manifest iron deficiency (23). Absorption rate rate on fasting as well as after breakfast was me... | 408,116 | [
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[Automatic analysis of long-term EEG in epilepsy. First experiences with a new part-automatic analytic system (author's transl)]. | A new equipment for automatic analysis of prolonged EEG derivations is demonstrated. Spikes, waves and SW-combinations are detected and counted separate; counted EEG signals are written with paper speed of 25 mm per sec. Results of a 3-channel-derivation with 1-channel-analysis are shown in a time compressed graphic de... | 408,119 | [
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Separation of functional and non-functional beta subunits of thyrotropin preparations by polyacrylamide gel electrophoresis. | Electrophoretic patterns of intact human and bovine TSH and bovine LH can be clearly distinguished from those of their subunits in 12% polyacrylamide gels, thus providing an easy method of examining subunit recombination. Two distinct components of both bovine and human TSH-beta subunits are observed, of which only one... | 408,127 | [
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Plasma secretin concentration in man: effect of intraduodenal glucose, fat, amino acids, ethanol, HCl, or ingestion of a meal. | The effect of infusing isotonic saline, isotonic and hypertonic glucose, fat emulsion, amino acids. ethanol, and hydrochloric acid into the duodenum on the plasma concentration of immunoreactive secretin was studied in seven normal subjects. Only hydrochloric acid showed any effect. After acidification of the duodenum ... | 408,145 | [
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0.04791902,
0.1497542,
0.02434559,
0.0890965... |
Cortical cells projecting to the dorsal column nuclei of rhesus monkeys. | Corticals cells projecting to the dorsal column nuclei (DCN) of Rhesus monkeys have been identified after unilateral or bilateral injection of horseradish peroxidase (HRP) into the dorsal medulla. HRP-positive neurons identifiable as the source of cortico-DCN projections were pyramidal cells in layer V whose largest di... | 408,162 | [
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0.572759,
0.041990... |
A tissue-selective prostaglandin E2 analog with potent antifertility effects. | N-methanesulfonyl 16-phenoxy-omega-tetranor PGE2 is a prostaglandin analog which is markedly more tissue selective than PGE2. This compound is 10-30 times more potent than PGE2 in animal models which are considered relevant to antifertility effects in humans. In pharmacological tests which are believed to be predictive... | 408,180 | [
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0.4266247,
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0.2369193,
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... |
Activation of complement by opportunist pathogens and chemotypes of Salmonella minnesota. | Washed cells of Staphylococcus aureus, Escherichia coli, Proteus mirabilis, Pseudomonas aeruginosa, and Salmonella minnesota chemotypes (S, Rb, and Re) were tested for their ability to activate the alternative complement pathway (ACP). Parameters of ACP activation were (i) conversion of C3 in 10 mM ethyleneglycol-bis-(... | 408,268 | [
-0.08499981,
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0.2610135,
0.0255227... |
Effect of anti-mu-chain-specific immunosuppression on Chikungunya virus encephalitis of mice. | Mice neonatally immunosuppressed with anti-mu antiserum failed to produce circulating antibodies to sheep erythrocytes and showed a marked decrease in circulating immunoglobulins. However, when they were intracerebrally infected with Chikungunya virus (a group A togavirus), they showed a mortality rate consistently low... | 408,271 | [
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0.325615,
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... |
Biological properties of Rickettsia prowazekii strains isolated from flying squirrels. | Four strains of Rickettsia prowazekii, isolated from flying squirrels (Glaucomys volans volans) from Florida and Virginia, were compared with other strains of the typhus biotype, two previously established strains each of R. prowazekii and R. typhi and one strain of R. canada, for similarities in a number of unrelated ... | 408,272 | [
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0.1605674,
0.00243667,
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... |
Condylar fractures of the mandible. III. positional changes of the chin. | Positional changes of the chin (symphysion = sy) following unilateral condylar fractures of the mandible were studied in 21 children and 20 adults by means of repeated radiographic examinations. On each occasion and for each individual the actual position of the sy was related to an estimated normal position. In those ... | 408,285 | [
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-0.0... |
Treatment of mandibular fractures by means of stable internal wire fixation. | Treatment according to the principles of stable internal fixation offers great advantages for fractures of the mandibular body. Most authors believe that a stable internal fixation can be achieved only by means of bone plating or screw fixation. At Groningen a wire connection was designed by BRONS which could be consid... | 408,286 | [
-0.2260878,
0.6273956,
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0.3444205,
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0.1218584,
0.1395749,
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0.07479572,
0.1590319,
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0.... |
Peroxidase permeability of the cryogenic chorioretinal adhesion. | Under normal conditions the retinal pigment epithelium does not permit passage of peroxidase tracers. Photocoagulation disrupts this barrier. Rhesus monkeys which received transconjunctival cryotheropy showed a similar disruption, with leakage of horseradish peroxidase into the retina. This leakage persisted for the 6-... | 408,292 | [
-0.04171438,
-0.1560845,
-0.310446,
0.01604486,
-0.08246037,
-0.2914982,
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0.04474101,
0.3976926,
0.1122061,
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0.04371759,
0.1108368,
-0.5463797,
0.140466,
0.0657984,
-0.1846188,
0.05538507,
0.07788721,
0.0961808,
... |
A quantitative assay to study cell movement in the myxobacteria. | A simple quantitative assay has been developed to test the rate of cell movement of myxobacteria. The assay employs an agar surface and at no time are the cells cultured in a liquid environment. Isolation of a rate-increasing substance(s) from fruiting Myxococcus xanthus is reported. The understanding of the aggregativ... | 408,365 | [
-0.02381263,
-0.09614926,
-0.1332037,
0.001199798,
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0.4392982,
0.1091604,
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0.1138979,
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0.2371291,
0.5681646,
-0.1768208,
-0.1715113,
... |
Some effects of calcium on the activation of human factor VIII/Von Willebrand factor protein by thrombin. | When Factor VIII/von Willebrand factor (FVIII/vWF) protein is rechromatographed on 4% agarose in 0.25 M CaCl(2), the protein and vWF activity appear in the void volume, but most of the FVIII procoagulant activity elutes later. Recent evidence suggests that the delayed FVIII procoagulant activity is a proteolytically mo... | 408,379 | [
-0.1253584,
0.178801,
-0.3291363,
-0.05157135,
0.08575491,
-0.3053922,
0.08032037,
0.1976917,
-0.07315177,
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0.1224332,
0.2561167,
0.03968163,
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0.005842133,
-0.2556346,
0.0413724,
-0.08292439,
0.2832288,
0.2392733,
0.1654432,
-0.1667746,
... |
Immunologic classification of Neisseria gonorrhoeae with micro-immunofluorescence. | A reproducible immunologic classification of Neisseria gonorrhoeae strains has been achieved by the micro-immunofluorescence (Micro-IF)3 method by using formalinized whole organisms as test antigens and mouse antisera prepared by i.v. immunization with the whole organisms as antibody. Immunologic differences among Neis... | 408,415 | [
0.2059704,
0.01797315,
0.07480112,
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0.2351812,
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0.0575981,
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0.02748878,
0.2633798,
0.06320735,
0.005629222,
0.2395861,
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0.1646642,
0.09005074,
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0.06856073,
0.2071676,
0.1184215,
-0.2546339,
... |
[Occurrence of purine deoxyribosides in urine (author's transl)]. | It was shown that purine deoxyribosides are normal constituents of human urine. Healthy probands excrete about 25 microgram (41% of the total urinary deoxyribosides) per 24 h. Purine deoxyribosides were determined as the acid-labile fraction of the total deoxyribosides by the microbiological assay with Lactobacillus ac... | 408,460 | [
-0.005555408,
0.01824227,
-0.2459541,
0.1306517,
0.3503145,
-0.3910899,
-0.4438378,
0.1377218,
0.05109191,
-0.2373115,
0.1434179,
0.2661566,
0.2569668,
0.1635831,
-0.8802706,
-0.0436815,
-0.251475,
0.1932072,
0.008443226,
0.1437439,
0.4013973,
-0.01044348,
-0.1928372,
-... |
Kerosene absorption in primates. | Kerosene, labeled with 3H-toluene or 14C-hexadecane, was given to baboons by nasogastric tube after a tracheostomy had been performed. Six hours later the animals were killed and samples of tissues taken for analysis. The radioactive label was recovered from all the tissues analyzed. 3H-toluene appeared to be absorbed ... | 408,472 | [
-0.03824188,
-0.1926822,
-0.1609203,
-0.1666424,
-0.0956003,
-0.1318336,
-0.3264775,
-0.4593674,
0.02839021,
-0.1507329,
0.4053944,
-0.1433897,
0.05186075,
-0.003193228,
-0.25561,
-0.001228936,
-0.5644354,
0.4163682,
-0.006684509,
0.2110117,
0.2720032,
0.4932874,
0.363483... |
Pyrrole esters of tropanols and related structures as analgesics. | 2,4,5-Trimethylpyrrole-3-carboxylic acid esters of tropanols and related monocyclic amino alcohols were synthesized and evaluated for analgesic activity by the mouse hot-plate and Nilsen methods. 1-Methyl-4-piperidinol 4-(2,4,5-trimethylpyrrole-3-carboxylate) (7) exhibited activity in the morphine--codeine range (mouse... | 408,488 | [
-0.1119661,
0.2470315,
-0.3323719,
-0.03492016,
0.1464329,
0.008674772,
-0.2366035,
-0.07158916,
0.2584389,
-0.02290407,
0.03527695,
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0.3105893,
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0.1122422,
-0.442923,
0.2734173,
-0.01147973,
0.4441828,
0.03100643,
0.06212393,
-0.023610... |
Inhibition of different serotypes of Listeria monocytogenes by enterocins in solid and liquid media. | Twenty-one enterocinogenic strains of enterococci were examined for their ability to inhibit 51 strains of Listeria monocytogenes belonging to eight different serotypes; 50 strains of L. monocytogenes were uniformly inhibited on solid media and in broth cultures by strains of Streptococcus faecium. However, only four s... | 408,493 | [
0.03967804,
0.04313076,
-0.2826461,
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0.09829183,
-0.3120298,
0.04711517,
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0.1716376,
0.05424861,
0.01043184,
0.2642361,
0.01007379,
0.1016308,
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-0.5701654,
-0.1074868,
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0.0556522,
0.402692,
0.06900511,
-0.261997,
... |
Oncornavirus-like particles in squirrel monkey (Saimiri sciureus) placenta and placenta culture. | Oncornavirus-like particles similar in morphology to type D particles were observed in 1 of 2 squirrel monkey (Saimiri sciureus) placentas. Intracytoplasmic type A particles, immature virus particles, and mature viruses with eccentric or occasionally centric nucleoids were associated with placental syncytiotrophoblasts... | 408,507 | [
0.1289948,
0.2297685,
0.006345695,
0.07524441,
0.3604935,
-0.03352131,
-0.4166475,
0.1620243,
0.2637102,
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0.166095,
-0.1838904,
0.1228823,
0.0831034,
-0.2594461,
-0.2155621,
-0.3812385,
-0.1097999,
0.2898781,
-0.07645861,
0.4068565,
0.3277561,
-0.1357588,
-0.... |
[Mechanism of nitroglycerin action]. | Data are presented on the effect of nitroglycerin upon the intracardiac haemodynamics studied by means of echocardiography in normal individuals and in patients with ischaemic heart disease. Three types of changes in the intracardiac haemodynamics under the effect of the drug were revealed. The possible mechanism of ac... | 408,554 | [
-0.2352138,
0.06010365,
-0.342888,
-0.09947561,
0.2539973,
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0.03927762,
-0.05435198,
0.1078772,
0.09979627,
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-0.3616303,
0.1115571,
-0.1547185,
0.29355,
0.3188411,
0.0733205,
-0.02361173,
... |
[Epiphase carotenoids of the blue-green alga Anabaena variabilia]. | Epiphase carotenoids were studied in the cells of the obligate phototrophous blue-green alga Anabaena variabilis. Ten pigment zones were detected by column chromatography on alumina and by TLC on cellulose and Silufol UV-254 plates. TLC in the B layer and paper chromatography did not reveal all pigment zones obtained o... | 408,584 | [
0.1206092,
0.1393738,
0.2119165,
-0.1337947,
0.08338954,
-0.3174219,
-0.4239663,
0.001770175,
0.1297952,
-0.03059682,
0.1073846,
0.1786476,
-0.2848734,
-0.2102898,
-0.364183,
0.08113566,
-0.4745583,
0.2348077,
0.1614549,
0.4581287,
0.6699665,
0.2289829,
-0.4185724,
0.21... |
The genetic organization of arginine biosynthesis in Pseudomonas aeruginosa. | Six loci coding for arginine biosynthetic enzymes in Pseudomonas aeruginosa strain PAO were identified by enzyme assay: argA (N-acetylglutamate synthase), argB (N-acetylglutamate 5-phosphotransferase), argC (N-acetylglutamate 5-semialdehyde dehydrogenase), argF (anabolic ornithine carbamoyl-transferase), argG (arginino... | 408,599 | [
0.06252772,
0.06066045,
-0.1861705,
0.2875715,
-0.1409198,
0.06062641,
-0.07094432,
0.1179182,
0.1031798,
0.3062162,
-0.06163434,
0.3245372,
-0.2734682,
0.1456316,
-0.2267519,
0.1096254,
-0.151179,
0.07884274,
0.06177794,
0.1337567,
0.1454258,
0.3436889,
-0.3839728,
-0.... |
[Hypertrophic cardiomyopathies (author's transl)]. | Because of their rapidly changing hemodynamic inconstancy depending on many, sometimes competing, processes, hypertrophic cardiomyopathies present a clinical picture extraordinary among the cardiac diseases, with severely altered diastolic compliance of the left ventricle and a functional stenosis in the obstructive fo... | 408,613 | [
-0.225584,
0.2218562,
0.04808248,
-0.07845262,
0.1123107,
-0.2300363,
-0.1088729,
-0.1835473,
0.03820143,
0.04644134,
0.1580659,
0.4515065,
-0.1379124,
-0.00469063,
-0.6132568,
-0.1558502,
-0.3753797,
0.09973177,
0.06075539,
0.0135053,
0.1871597,
-0.1141764,
-0.2122291,
... |
[Rheocardiography in the orthostatic test (author's transl)]. | Cardiac output and peripheral flow resistance were determined rheocardiographically under resting conditions and in orthostasis in 175 patients who came for examination to clarify circulatory disturbances with suspected orthostatic dysregulation. The method was examined critically and compared with other procedures. Di... | 408,615 | [
-0.02045764,
-0.1348003,
-0.2209,
-0.2775929,
-0.03738807,
-0.2831215,
-0.4129383,
-0.2048095,
-0.09109907,
0.07067284,
0.1385842,
0.06112098,
-0.321271,
-0.2002675,
-0.487191,
-0.06855034,
-0.4813352,
0.2756248,
-0.3008754,
0.3611431,
0.1858674,
-0.01420174,
0.173076,
... |
[Viruses as causal agents of gastroenteritis in infants and young children (author's transl)]. | Electron microscopic examination of stool samples from 195 infants and young children with acute gastroenteritis revealed rota virus in 31 samples (= 16%), corona virus in 44 samples (= 23%) and adenovirus in 13 samples (= 7%). Viruses were excreted for between 4 and 8 days in patients infected with rota virus and coro... | 408,644 | [
-0.1341535,
-0.2042412,
-0.06978323,
0.2310623,
0.1779039,
0.005918449,
-0.358694,
-0.1245654,
-0.2269443,
0.1327706,
0.2403949,
0.3575452,
0.05727515,
0.0164187,
-0.4078779,
-0.02570857,
-0.3349153,
0.17173,
0.4198589,
0.1603055,
0.2465858,
0.01821886,
-0.1250933,
0.07... |
[Pentazocine--an addiction problem? (author's transl)]. | Pentazocine dependencies are rare. In a period of 5 years, 60 were notified. The majority of these were not dependent. Of 46 utilizable notifications, 38 were false, 5 had taken pentazocine only temporarily or not at all. 19 received it for chronic or recurrent pains, 13 were polytoxicomaniacs, and 1 patient could not ... | 408,653 | [
-0.2524814,
-0.1794138,
-0.2492345,
0.05295453,
0.2248251,
-0.08814465,
-0.259974,
-0.02607469,
-0.07134693,
-0.1776114,
0.1604241,
0.1214719,
0.09681053,
0.2246163,
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0.2238868,
-0.06296917,
0.2301213,
0.2644069,
-0.1192027,
-0.08056963,
... |
[Clinical trial of a combination preparation of clonidine and cyclothiazide (author's transl)]. | Three dosage combinations of clonidine and cyclothiazide were tested in at least 20 patients each, under clinical (4 weeks) and oupatients (longterm) conditions, in order to find a suitable combination with fewer side effects than the single drugs with at least equal efficacy for the longterm treatment of hypertension.... | 408,656 | [
0.003966015,
0.1841093,
0.1618008,
0.1208007,
0.2373812,
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-0.4717757,
0.04490302,
0.2583451,
-0.1200851,
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-0.08018319,
0.0001754617,
0.1898536,
-0.7034736,
-0.0682849,
-0.7091665,
0.1630745,
-0.2735817,
0.2719045,
0.3421501,
-0.03479315,
-0.1577269,... |
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