title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Ultrasonic backscatter from human liver tissue: its dependence on frequency and protein/lipid composition. | Ultrasonic volume backscatter by postmortem human liver was investigated in the 1 to 5 MHz frequency range. Representative values of the backscatter coefficient, its range, and frequency dependence were determined. The backscatter level correlated significantly with protein content in normal livers and with lipid con... | 410,833 | [
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Unusual echographic appearance of a Courvoisier gall bladder. | A patient who had been jaundice for more than four months was examined with diagnostic ultrasound. Ultrasound examination revealed that the patient had a solid-appearing mass in the region of the gall bladder, in addition to findings diagnostic of obstructive jaundice. A probable mass was also noted in the head of the ... | 410,841 | [
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Epidemiological information from active and passive pyocine typing of Pseudomonas aeruginosa. | An investigation was carried out to determine the value of active and passive pyocine typing in the study of Pseudomonas aeruginosa infections acquired in hospital. Active typing was a more reliable and reproducible method than passive typing. Both methods were used in studies of nine outbreaks of infection. In six of ... | 410,935 | [
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The mutational spectrum of procarbazine in Drosophila melanogaster. | The antineoplastic agent Procarbazine was tested for the induction of genetic damage in Drosophila melanogaster. The compound was administered to adult males by oral application. The following types of genetic damage were measured: (1) sex-linked recessive lethals; (2) dominant lethals; (3) total and partial sex-chromo... | 411,030 | [
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Preclinical effects: unlearned behavior. | The cannabinoids produce a variety of effects on unlearned behavior in different animal species. The voluminous literature pertaining to cannabis and unlearned behavior has been reviewed in the five previous Marihuana and Health Reports (1971 through 1975). The present chapter relies heavily on these previous reports f... | 411,045 | [
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Endodontic morphology. III. Canal preparation. | Three hundred nine root canals in 164 extracted human teeth were prepared with endodontic instruments for obturation by the lateral condensation technique. Variations in tooth lengths for each group of teeth were marked, pointing up the need for adequate control of instruments through careful assessment of tooth length... | 411,080 | [
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[The occurrence of Bacillus cereus in dairy products (authors transl)]. | During one year 1390 samples of pasteurized milk products from five different dairies were examined for content of B. cereus. The examination was done on the day of packaging and after incubation at 17 degrees C for 24 hrs. as well. On examination on the day of packaging 8.1 % were positive. No difference could be demo... | 411,110 | [
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[Parenteral nutrition. Experience of 2 years]. | Total parenteral nutrition is a new method, in our media, that permits the direct administration to the blood stream of all the necesary elements for cellular synthesis. Total parenteral nutrition finds in the field of gastroenterology a wide range of indications to correct and prevent malnutrition in a patient who can... | 411,123 | [
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Increasing the incidence and the size of successful experimental composite ear grafts by advance preparation of the recipient bed. | Composite grafts were transferred from one ear to the other in adult macaque monkeys. Evidence was found that preparation of the recipient bed (cutting a wedge-shaped hole from the rim inward, 10 or 11 days ahead of transfer) would increase the incidence of complete takes and would also increase the size of grafts that... | 411,148 | [
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[Economic aspects of diseases and dairy herd health programs in the Netherlands with special reference to mastitis (author's transl)]. | Animal diseases cause considerable losses among dairy cattle in the Netherlands. Model calculations show that the loss on farm level from animal diseases is approximately Dfl 440.--per cow per annum. Increasing attention is being paid to one of them e.g. mastitis. This disease causing an annual loss on farm level of ap... | 411,196 | [
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On the pathogenesis of simple renal cysts in the adult. A microdissection study. | The simple cyst in the adult seems to be mainly an acquired disorder. Microdissection of the nephron in the adult kidney points to the presence of diverticula on the distal tubule as the starting point of the affection. A degree of obstruction in the urinary tract together with normal involutional phenomena of the basa... | 411,204 | [
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[Isolation of influenza strains identical to influenza virus A/Anglia/42/72 from semisynanthropic bird species in Rovno Province, the Ukrainian SSR]. | Two strains of influenza virus, A/wagtail/Ukraina/107/74 and A/dove/Ukraina/111/74, were isolated in virological studies of semisynanthropic species of birds shot near villages in the Rovno region (Western Ukraine). Both strains were found to be antigenically identical with influenza A/England/42/72 virus. | 411,259 | [
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[Insulin in mollusks and its role in regulating carbohydrate metabolism]. | Some experiments including glucose loading, insulin or antiinsulin serum injection and in vitro investigations on bivalve freshwater molluscs Anodonta cygnea and Unio pectorum were carried out. All the treatments used were found to cause shifts in glycaemic level, glycogen content in muscles and glycogen-synthetase act... | 411,281 | [
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Infusion thrombophlebitis in a surgical department. | In hospitals where 5% glucose is the solution most often infused, the incidence of thrombophlebitis has been found to be 27-43%. In an attempt to reduce this incidence, the following principles for the administration of intravenous solutions were established in a surgical department: (1) No cannula to be placed in the ... | 411,297 | [
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Failure of luteinizing hormone-releasing hormone and insulin to further augment thyrotrophin release in primary hypothyroidism. | The effect of luteinizing hormone-releasing hormone (LH-RH) and insulin-induced hypoglycaemia on the release of thyrotrophin (TSH) was studied in five patients with primary hypothyroidism. All five patients had elevated TSH levels with an exaggerated rise in response to thyrotrophin-releasing hormone (TRH). No rise ove... | 411,302 | [
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[The fixation of intracellular carbohydrates in the chondrocytes (author's transl)]. | The chondrocytes of the epiphysis contain several polysaccharides, not only glycogen, but also proteoglycans (MPS). Therefore the fixation of chondrocytes is difficult. In regard of fixation we must consider, that macromolecules of proteoglycans have a considerable water content (the effective hydrodynamic volume), fur... | 411,311 | [
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Ontogenetical and histochemical studies on the translator apparatus in Calotropis procera R. Br. I. The retinaculum. | Translator apparatus consists of 2 parts--the corpusculum, which is attached to the margin of the stigmatic head between the anthers, and a pair of arms by which the corpusculum is attached to the pollinia of the adjacent anther halves. Retinaculum spans the lateral blade of the corpusculum to the acellular beak of the... | 411,312 | [
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Staining of human pituitary glands with lead hematoxylin in comparison with other histochemical procedures, including the immunoenzyme technique. | Human pituitary glands and pituitary adenomas, obtained by surgery or at autopsy, have been stained with lead hematoxylin and the results were compared with those of other histochemical procedures, including the immunoperoxidase technique. Lead hematoxylin positivity was found in the cytoplasm of melanocorticotroph, th... | 411,317 | [
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Serologic studies of the diagnosis and nosology of human leukemia. | Nonhuman primate antisera to human leukemia-associated antigens and to normal T- and B-lymphocyte antigens are useful reagents for detecting and classifying leukemic cells in a microcytotoxicity assay. These antisera are able to distinguish lymphocytic from myeloid leukemia cells, and can also identify acute myelomonoc... | 411,368 | [
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[Sarcosporidias of cloven-hoofed wild animals. Sarcosporidias in wild deer]. | 500 adult roes and 100 fawns were examined microscopically for the presence of Sarcocystis gracilis von Ratz, 1901. 95.80 per cent of the roes examined had Sarcosporidias. The parasites were noticed macroscopically in less than a third of them. The abdominal muscles were affected most frequently and most strongly. The ... | 411,394 | [
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Refractometry as a measure of the immunoglobulin status of the newborn dairy calf: comparison with the zinc sulfate turbidity test and single radial immunodiffusion. | Immunoglobulins were quantitated by single radial immunodiffusion in 34 female Holstein-Friesian calves which had been kept with their dams for the first 24 hours of life. The mean immunoglobulin G1 (IgG1) concentration was 1.063 g/dl; IgG2, 0.093 g/dl; IgM, 0.171 g/dl; and IgA, 0.125 g/dl. Both serum total protein as ... | 411,400 | [
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Comparison of cardiorenal functions between women and female rhesus macaques. | Selected cardiorenal functions for conscious and chaired rhesus macaques were compared directly and indirectly with corrections for body weights and surface areas to well-established base-line values for human subjects. Certain functional differences between species and conditions of measurement do not allow all experi... | 411,401 | [
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Drug resistant tuberculosis in a large southern California hospital. | Rates of in vitro resistance to antituberculous drugs were examined for all patients hospitalized with active tuberculosis between January 1969 and December 1972, and between March 1975 and September 1976. During the former period, in 31.5 per cent of patients, tuberculosis was resistant to one or more drugs, and in 12... | 411,406 | [
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Gender and environment as determinants of behavior in infant common baboons (Papio cynocephalus). | Two groups of infant baboons were observed. The breast-fed group was housed in a gang cage with nursing mothers (n = 13) and the other motherless group was in a wire-cage nursery habitat (n = 20). Differences in behavior due to gender and environment were tested by analysis of variance. The results do not support the h... | 411,455 | [
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Vascular clearance of venezuelan equine encephalomyelitis viruses as a correlate to virulence for rhesus monkeys. | The epizootic Trinidad donkey strain of Venezuelan equime encephalomyelitis virus (VEE) was cleared slowly from the circulation of rhesus monkeys following intravenous inoculation, while the live, attenuated vaccine strain, TC-83, was cleared rapidly. The efficent clearance of TC-83 vaccine may be a factor in the lower... | 411,457 | [
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Café-au-lait spots of the fundus in neurofibromatosis. | Mild pigmentary changes found in the fundi of two patients with neurofibromatosis, resembled café-au-lait spots homologous with skin manifestations of the disease. In one, associated retinal hamartomas were present. The café-au-lait lesions were clinically distinct from previously reported uveal melanomas and may repre... | 411,462 | [
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Fragments produced by digestion of human immunoglobulin G subclasses with pepsin in urea. | It was previously shown that digestion of human IgG1/kappa myeloma proteins with pepsin in the presence of 8 M-urea produces fragments which differ from other proteolytic fragments of IgG, including those produced by peptic digestion in aqueous buffers. The two large urea/pepsin fragments each consist of three peptides... | 411,484 | [
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Thermostability at ultrahigh temperatures of thermolysin and a protease from a psychrotrophic Pseudomonas. | Thermal inactivation at 110-150 degrees C of thermolysin (EC 3.4.24.4), produced by the thermophile Bacillus thermoproteolyticus, and the extracellular protease of Pseudomonas sp. MC60 a psychotroph, were investigated at 130 degrees C, both enzymes had approximately the same deltaH (22 kcal/mol) and deltaS (-13.5 cal/m... | 411,519 | [
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0.2896442,
0.1562506,
-0.3137183,
-0.02293513,
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0.3045685,
-0.02623999,
0.1688081,
0.3689608,
0.1169062,
0.4239452,
-0.09844606,... |
Some properties of the extracellular protease produced by the psychotrophic bacterium Pseudomonas fluorescens strain AR-11. | The major extracellular protease from Pseudomonas fluorescens strain AR-11 has been partially purified by a factor of 300 by a combination of DEAE-cellulose ion-exchange chromatography and gel filtration. The enzyme had a molecular weight of 38 400 and exhibited optimum activity with isoelectrically precipitated casein... | 411,520 | [
-0.1559038,
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Uptake studies of taurine in vivo and its effects on the course of experimental focal epilepsy in rats. | The passage of orally administered taurine across the intestinal wall to the blood plasma and target sites of neuromuscular excitability has been studied. This has been correlated with the effect of repeated oral dosing on the manifestations of cobalt-induced epilepsy in the rat. The blood-brain barrier and the organ d... | 411,544 | [
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0.4115904,
0.1588563,... |
Physiological control of alkylsulfatase synthesis in Pseudomonas aeruginosa: effects of glucose, glucose analogs, and sulfur. | Pseudomonas aeruginosa (isolated from soil) synthesizes an alkylsufatase allowing this bacterium to utilize sodium hexan-1-yl sulfate as a source of carbon and sulfur for growth. The formation of the enzyme was induced by this and by other (C4-C16) primary alkylsulfate esters as well as by some (C-8 and C-9) primary al... | 411,561 | [
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0.2704599,
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... |
The effect of Waring Blendor treatment on transformation in Bacillus subtilis. | Treatment of competent Bacillus subtilis in a Waring Blendor for 10 s increases transformability of the culture about twofold while reducing the attachment of DNA to competent cells by 80%. The effectiveness of attached DNA in producing transformants is increased 10-fold by this treatment. The uptake of transforming DN... | 411,563 | [
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Alterations in fecal microflora enzymes related to diet, age, lactobacillus supplements, and dimethylhydrazine. | The bacterial enzymes, beta-glucuronidase, azoreductase, and nitroreductase, have been measured in the fecal microflora of rats. The effects of diet, advanced age, Lactobacillus acidophilus supplements, and dimethylhydrazine on these microbial enzymes activities have been determined. The shift from a grain to a meat di... | 411,567 | [
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0.2... |
Pharmacologic disposition of DL-alanosine in mice, rats, dogs, and monkeys. | The pharmacologic disposition of DL-alanosine was studied in mice, rats, dogs, and monkeys. The major portion of the parenterally administered drug was excreted in the urine by all of the species studied; however, in rodents an important fraction of the dose was expired as CO2. Organs in which DL-alanosine accumulates ... | 411,570 | [
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0.133... |
[Inhibition of biological methylations by t,t-farnesylacetone, a constituant of the androgenic gland of the male crab, Carcinus maenas]. | t, t-farnesylacetone 1 and hexahydrofarnesylacetone 2 have been previously identified in extracts from the androgenic gland of the male Crab Carcinus maenas. These compounds inhibit in vitro the methylation of E. coli B tRNA and of Calf thymus histones with S-adenosylmethionine methyl-14C as methyl donor and methylases... | 411,588 | [
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0... |
Serum gentamicin assay by high-performance liquid chromatography. | We describe a high-performance liquid chromatographic method for the quantitative determination of gentamicin in serum. The antibiotic was separated from serum by passage through a silicic acid column, derivatized with o-phthalaldehyde, and eluted with ethanol. The derivatized gentamicin was then separated into all thr... | 411,610 | [
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Immunological studies on beef-heart ubiquinol--cytochrome c reductase (complex III) | Antibodies against isolated beef-heart ubiquinol--cytochrome c reductase (complex III) have been characterized. Antibodies to complex III react strongly with isolated beef heart complex III and intact beef heart mitochondria, as shown by immunodiffusion and rocket electrophoresis experiments. The complex III content of... | 411,653 | [
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0.07... |
Comparative studies of lactate dehydrogenases in lactic acid bacteria. Amino-acid composition of an active-site region and chemical properties of the L-lactate dehydrogenase of Lactobacillus casei, Lactobacillus curvatus, Lactobacillus plantarum, and Lactobacillus acidophilus. | The molecular weight, the amino acid composition and the N-terminal and C-terminal amino acids of two allosteric (Lactobacillus casei, L. curvatus) and two non-allosteric (L. plantarum, L. acidophilus) L-lactate dehydrogenases, purified to homogeneity by affinity chromatography, were determined. The amino acid composit... | 411,654 | [
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-0.1... |
The preparation of ligandin with glutathione-S-transferase activity from porcine liver cytosol affinity chromatography on bromosulphophthalein-Sepharose. | A simple and rapid method for the purification of porcine ligandin with glutathione-S-transferase activity is presented. After ion-exchange chromatography on DEAE-Sephadex, ligandin is isolated from porcine liver cytosol by affinity chromatography on bromosulphophthalein-Sepharose and gel filtration of Sephadex G-100. ... | 411,659 | [
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-... |
Hereditary deficiency of phosphoglycerate kinase: a new variant in erythrocytes and leucocytes, not associated with haemolytic anaemia. | An X-chromosome linked phosphoglycerate kinase deficiency in erythrocytes and leucocytes was discovered in a large German kindred. Seven males of two generations were found to have only 21% of the normal enzyme activity in their erythrocytes, and twelve females of three generations showed various degrees of this defect... | 411,673 | [
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... |
Electrophoretic variation in esterases in 3 wild-type and respective mutant strains of Aspergillus flavus. | Wild-type strains and auxotrophic mutants of Aspergillus flavus, differing regarding aflatoxin production, were tested for esterases isozymes. Esterases variation was found in all strains used, and a possible correlation between the pattern of esterase bands and aflatoxin production is suggested. | 411,683 | [
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Purification and immobilization of human carbonic anhydrase B by using polyacrylamide gel. | Human erythrocyte carbonic anhydrase B was purified and immobilized in polyacrylamide gel. As compared to the soluble enzyme, the immobilized enzyme was considerably more resistant to heat and sulphanilamide action. | 411,684 | [
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Studies on the control and dynamics of thyrotropin secretion from isolated adenohypophyseal cells. | Thyrotropin (TSH) secretion from isolated anterior pituitary cells has been studied using the technique of cell column perifusion. The consistency in secretory rate and temporal profiles of TSH output in response to stimulation illustrated that the system is suitable for studying the kinetics of stimulation and inhibit... | 411,704 | [
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An endemic focus of Trypanosoma cruzi infection in a subhuman primate research colony. | Leishmanial forms of Trypanosoma cruzi with multifocal pseudocysts were identified in a deceased adult female rhesus monkey (Macaca mulatta) that had been maintained in an outdoor primate colony in southern Texas. Subsequent clinical investigation of the remainder of the colony identified 20 additional monkeys seroposi... | 411,770 | [
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Simplified micro perchlorination method for polychlorinated biphenyls in biological samples. | Simplified methodology is presented for the micro determination of polychlorinated biphenyls (PCBs) in biological samples, by conversion to the decachlorobiphenyl (DCB) derivative. Beef adipose tissue and human milk extracts were fortified with PCB standards at 0.1--5.0 ppm, and perchlorinated with antimony pentachlori... | 411,780 | [
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Ferredoxin and formyltetrahydrofolate synthetase: comparative studies with Clostridium acidiurici, Clostridium cylindrosporum, and newly isolated anaerobic uric acid-fermenting strains. | Six strains of Clostridium acidiurici and three strains of C. cylindrosporum were isolated from soil samples by enrichment culture with uric acid as the source of carbon, nitrogen, and energy. The newly isolated strains were characterized by their spore morphology and the amounts of glycine and formate formed by the fe... | 411,781 | [
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... |
Inhibition of thyrotrophin-releasing hormone responsiveness by physiological concentrations of thyroid hormones in the cultured rat pituitary gland. | Diced quarter anterior pituitaries from mature females Wistar rats were cultured in synthetic medium with or without added serum. Using each culture as its own control, the thyrotrophin-releasing hormone (TRH) dose-thyrotrophin (TSH) response characteristics of both media were similar; significant TSH secretion being s... | 411,865 | [
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Cross reactivity of rabbit antibodies against purified animal enzymes. Comparison of enzymes of human and animal origin, II. | Enzyme preparations used for quality control of enzyme activity determinations in clinical chemistry should be very similar to human enzymes. Antibodies against e.g. porcine enzymes show cross reactivity with the corresponding human enzymes, indicating partial identity of the enzyme proteins. As the enzyme-antibody pre... | 411,881 | [
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Low-dose intravenous insulin: treatment of diabetic ketoacidosis in children (suitability for use in community hospitals). | A regimen is described to simplify current methods of ketoacidosis therapy by using only standard intravenous equipment and without requiring albumin administration. After an initial intravenous insulin bolus of 2 units, a dose of up to 3 units per hour was sufficient to bring patients out of ketoacidosis. No hypoglyce... | 411,882 | [
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Comparative metabolism of 17alpha-ethynyl steroids used in oral contraceptives. | The metabolism of mestranol, ethynylestradiol, norethynodrel, norethindrone, ethynodiol diacetate, lynestrenol, and norgestrel is reviewed. The estrogenic components of the oral contraceptives, mestranol or ethynylestradiol, have nearly identical metabolic pathways since mestranol is rapidly and almost completely conve... | 411,940 | [
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... |
Lead intoxication among demolition workers: the effect of lead on the hepatic cytochrome P-450 system in humans. | Overt clinical disease from undue lead exposure has become a relatively rare phenomenon in adult populations. However, exposure situations that may result in subclinical disease are not uncommon in various occupational settings. Five demolition workers, dismantling an old iron structure covered with lead-content paint,... | 411,946 | [
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0.01815456,
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0.33... |
Vivalan, a new anti-depressant-report on an out-patient trial. | The study on 20 patients referred from the psychiatric out-patients of the Jinnah Postgraduate Medical Centre, who were given Vivalan showed marked improvement in 14 patients (70%). Three showed mild improvement while three did not respond. The drug appears to be an advance in the range of anti-depressants presently av... | 411,955 | [
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Serotyping of Pseudomonas aeruginosa from patients with cystic fibrosis of the pancreas. | Serotyping of 30 mucoid strains isolated from cystic fibrosis patients was carried out by slide agglutination tests with both live and heat-killed cells and by tube agglutination test with heat-killed cells. Comparison of the results obtained by these 2 methods revealed that tube agglutination with heat-killed cells wa... | 411,970 | [
-0.2508764,
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0.03624981,
0... |
Evaluation of computer-aided monitoring of patients after heart surgery. | The medical and economic benefits of a computer-aided monitoring system were evaluated in a prospective, randomized study of 810 patients after open-heart surgery. The design of the study separated benefits of systematized postoperative care from benefits unique to the computer system and established measurable criter... | 412,015 | [
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Neutron spectral measurements in an intense photon field associated with a high-energy x-ray radiotherapy machine. | High-energy x-ray radiotherapy machines in the supermegavoltage region generate complex neutron energy spectra which make an exact evaluation of neutron shielding difficult. Fast neutrons resulting from photonuclear reactions in the x-ray target and collimators undergo successive collisions in the surrounding materials... | 412,048 | [
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0.284488,
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0.01874851,
-0.02949451,
0.07911303,
0.09737183,
0.6928606,
0.3604198,
0.05564997,
... |
[Studies on the risk of complications in transfemoral arteriography in infancy (author's transl)]. | Four cases of restricted circulation were found during follow-up examination of 42 infants after arteriography. In 3 of the 4 patients with restricted circulation, arteriotomy with vascular suture had preceded or had been performed in direct association with the arteriography. This strengthened the suspicion that such ... | 412,066 | [
0.04196202,
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0.4471886,
0.3386416,
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Anterograde transneuronal degeneration in the limbic system: clinical-anatomic correlation. | A 64-year-old man with diffuse atherosclerosis developed an organic mental syndrome, followed by hypothalamic symptoms. Autopsy showed an old large cystic infarct involving the left temporal lobe including the hippocampus, and atrophy of the ipsilateral fornix, mammillary body, hypothalamus, mammillothalamic tract, and... | 412,120 | [
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0.1379655,
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Sequence of the 3'-terminal 21 nucleotides of yeast 17S ribosomal RNA. | The sequence of the 3'-terminal 21 nucleotides of 17S ribosomal RNA from the yeast Saccharomyces carlsbergensis has been determined to be (Y)G-m62A-m62A-C-U-C-G-C-G-G-A-A-G-G-A-U-C-A-U-U-AOH. This sequence shows extensive homology with the 3'-terminal sequence of 16S rRNA from Escherichia coli including the presence of... | 412,171 | [
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0.2946292,
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0.13... |
Diagnosis of Chagas' cardiomyopathy. Non-invasive techniques. | The natural history of Chagas' disease and its manifestations when the heart is involved are detailed clinically and pathologically. Three phases are recognized: the acute phase, lasting from 1-3 months, the latent phase, which may last from 10-20 years, and the chronic phase, which has the most serious manifestations.... | 412,174 | [
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0.1852085,
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[Paths of corticosteroid biosynthesis in the adrenal glands of rhesus monkeys]. | In experiments in vitro corticosteroid formation from radioactive cholesterol in tha adrenal glands of monkeys (Macaca rhesus) was studied. A conclusion was drawn that pregnenolone and its hydroxy-derivatives were of the leading significance in the cortizol and corticosterone synthesis in the adrenal glands of monkeys.... | 412,183 | [
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0.3115476,
0.4839341,
0.01547284,
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... |
Deficits in passive-avoidance learning following atropine in the developing rat. | The maturation of cholinergic inhibitory mechanisms that may be involved in passive-avoidance learning was studied in rats 14, 17, 21, 25, 28, and 34 days of age. Acquisition and extinction of the conditioned response were examined under saline and atropine sulfate (5 mg/kg). Learning was also tested following scopolam... | 412,208 | [
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0.05365569,
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[Evolution of urinary tract tuberculosis in Switzerland during the last 18 years: respective diagnostic importance of radiology and bacteriology]. | In Switzerland as in other European countries, the incidence of urinary tuberculosis remained stable during the period 1957-1974, whereas a sharp fall in pulmonary tuberculosis was observable. The radiologic and bacteriologic findings in 125 cases personally observed over the last 18 years are presented. | 412,249 | [
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... |
Serum estradiol and progesterone during pregnancy and the status of the corpus luteum at delivery in cynomolgus monkeys (Macaca fascicularis). | Levels of estradiol and progesterone in peripheral serum of seven cynomolgus monkeys (Macaca fascicularis) were measured from about the 30th day of pregnancy until parturition. Although the pattern of each steroid in circulation differed somewhat from the respective patterns in rhesus monkeys (Macaca mulatta), there we... | 412,283 | [
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Gynecologic pathology in the rhesus monkey (Macaca mulatta). II. Findings in laboratory and free-ranging monkeys. | The most prevalent findings in reproductive tracts of 38 laboratory and 17 free-ranging Rhesus female monkeys were vaginitis, cervicitis, metritis, pelvic endometriosis and uterine adenomyosis. Several monkeys had cervical dysplasia and one had a serous cystadenoma. The findings in the two groups were similar although ... | 412,291 | [
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0... |
Epidermal intercellular relationships during carcinogenesis and cocarcinogenesis as revealed by scanning electron microscopy. | Investigations with the scanning electron microscope were carried out on the skin of 80 NMRI mice after treating them with small doses of the carcinogenic substance DMBA and the cocarcinogenic agent TPA, respectively. The results were correlated with histologic, transmission electron microscope and autoradiographic obs... | 412,299 | [
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The proliferation of chondrocytes and pannus in adjuvant arthritis. | Cell proliferation in the pannus formation of adjuvant arthritis was studied by autoradiography. It was found that after day 9 an increased cell proliferation starts in the joint capsule recessus and synovial villi on the injected side. From these proliferating cells a pannus, which during the first phase frequently co... | 412,302 | [
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The effect of cadmium administration in vivo on plasma testosterone and the ultrastructure of rat lateral prostate. | Electron microscope microanalysis, atomic absorption analysis and ultrastructural survey were used to investigate the effects of parenteral cadmium administration on the lateral prostate of rats. Early fine structural changes in the epithelial cells of the prostatic tissue were associated with the detection of cadmium ... | 412,304 | [
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[Titration of the antibodies to the Crimean hemorrhagic fever virus in a drop of the cell suspension from infected tissue cultures by means of indirect immunofluorescence]. | A comparatively simple method has been developed and tested for the detection and titration of antibody to Crimean hemorrhagic fever virus (CHF) by indirect immunofluorescence on slides with previously prepared acetone-inactivated virus in drops of cell suspension from infected BHK-21 and 6619 cell cultures. The antibo... | 412,325 | [
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... |
Reactivation of the EDTA-treated arginase from rat and calf liver. | 1. The anionic calf liver arginase, like the cationic rat liver enzyme, is inactivated by EDTA-treatment. The activity is fully restored by Mn2+. A smaller effect is observed with Cd2+, Ni2+ and Co2+. 2. The EDTA-inactivated calf liver arginase, unlike the rat liver enzyme, does not dissociate into subunits, and its mo... | 412,382 | [
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... |
[Fluorometric determination of the quality of FITC-anti influenza conjugates (author's transl)]. | A fluorometric method for the evaluation of FITC-anti influenza conjugates is described. The titre and that dilution required for the complete detection of antigens can be determined. It is possible to verify the probability of detection in per cent for any dilution stage and to compare objectively different batches. F... | 412,390 | [
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Degradation of the plant flavonoid phellamurin by Aspergillus niger. | We have previously described the structure of phellamurin, a plant flavonoid, as 3,4',5,7-tetrahydroxy-8-isoprenylflavanone-7-O-glucoside (17). Degradation of phellamurin by Aspergillus niger using modified Czapek-Dox medium as well as phellamurin or one of its degradation products as a sole carbon source, is reported ... | 412,468 | [
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0.2279887,
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Influence of modifications of physicochemical and biological properties of haptoglobin. VII. Immunochemical reactivity of haptoglobin with modified tyrosine residues. | Tyrosine residues in human haptoglobin (Hp) type 2-1 were modified by treatment with various amounts of N-acetylimidazole, iodine or tetranitromethane. Rabbit antisera directed against native Hp, Ac-Hp, 1-Hp and NO2-Hp in cross-reactions by immunoprecipitation showed serologic identify of native Hp and most of the modi... | 412,487 | [
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0.3497016,
0.06391824,
0.2473228,
-0.2596009,
... |
Cromolyn effects on vernal keratoconjunctivitis in children. | A double-masked, coded trial was undertaken to evaluate the effect of the topical administration of 2% cromolyn sodium eye drops on vernal keratoconjunctivitis in 14 children. One eye of each patient was treated for one year with cromoly, the other eye with placebo. Cromolyn reduced the characteristic vernal keratitis,... | 412,489 | [
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0.3018521,
0.004284504,
... |
The B-vitamin content of baboon (Papio cynocephalus) milk. | 1. The B-vitamins in milk from baboons (Papio cynocephalus) at various stages of lactation were measured microbiologically. 2. Mature milk contained, on average (microgram/ml): thiamin 0.18 riboflavin 0.74, nicotinic acid 3.2, folate 0.03, vitamin B6 0.70 vitamin B12 0.002, pantothenic acid 2.63, biotin 0.0065. 3. Colo... | 412,516 | [
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0.004660314,
-... |
Distribution and metabolism of prednisone in mice, dogs, and monkeys. | A chromatographic procedure that allows measurement of [3H]prednisone and [3H]prednisolone in biologic fluids and tissues was developed and used to determine some of the biochemical properties of prednisone and its distribution and metabolism in mice, dogs, and monkeys. When prednisone was added to mouse serum in vitro... | 412,589 | [
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0.06859046,
0.171148,
0.06783282,
-0.5... |
Evaluation of radiotherapay for localized inflammatory skin and perianal lesions in adult leukemia: A porspectively randomized double blind study. | Thirty-five episodes of localized infection among 20 patients with acute leukemia and granulocytopenia (less than 1000 cells/microliter) were treated with intensive supportive care including systemic antibiotics. In a double blind randomization, 17 of the episodes also received 400 rads of megavoltage irradiation to th... | 412,590 | [
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0.1301963,
0.0922538,
0.2144604,
0.23... |
Results for serum and plasma compared in 15 selected radioassays. | We evaluated the results for serum vs. plasma samples for 15 selected radioassay procedures, using 19 manufacturers' kits. Blood samples were collected with heparin, oxalate-fluoride, or ethylenediaminetetraacetate anticoagulants and compared with serum samples. Differences were demonstrated between serum and plasma wh... | 412,616 | [
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0.05509448,
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0.... |
Studies on excretion of renal antigens in normal and pathological urine. | The report deals with attempts to identify and quantitate renal antigens excreted into the urine of normal subjects and patients with renal disease. Although no useful information was obtained on the possible excretion of glomerular basement membrane antigens, renal tubular epithelial antigen (RTE) proved to be interes... | 412,624 | [
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0.196974,
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0.1384801,
-0.1043981,... |
Inhibition of bovine cerebral cortex prostaglandin synthetase by phenoxybenzamine and cyproheptadine in vitro. | 1. Bovine cerebral cortex (BCC) microsomes were isolated from fresh brain using standard techniques. 2. Two a-adrenoceptor antagonists (phenoxybenzamine and phentolamine) and two anti-serotonin compounds (cyproheptadine and cinanserine) were compared with the anti-inflammatory drugs indomethacin and keptoprofene for in... | 412,631 | [
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0.1318311,
0.7481053,
0.09315381,
0.3050296,
-0.1110001,
0.037... |
Viability of Leptospira interrogans serotype grippotyphosa in swine urine and blood. | Normal swine urine, devoid of its microbial flora, diminished the viability and virulence of Leptospira interrogans serotype grippotyphosa. Bovine serum albumin diluent effectively offset the urine's deleterious effects. Membrane filtration (0.45 micrometer) rendered urine free of bacteria, but permitted passage of lim... | 412,643 | [
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-0.09600485,
0.2147111,
0.1237783,
-0.21026... |
The effect of tablet formulation on the haemodynamic properties of glyceryl trinitrate. | A non-invasive haemodynamic study was carried out in 13 normal subjects to compare the pharmacodynamics of glyceryl trinitrate when formulated as a moulded tablet ('Nitrostat') rather than as a generic compressed tablet. The glyceryl trinitrate moulded tablet, with a much more rapid and predictable dissolution time, pr... | 412,646 | [
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0.4410254,
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0.00190883,
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0.008453161,
0.06887434,
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0.1802531,
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0.2727205,
0.3286256,
0.1181373,
0.03228157,
... |
Antimicrobial synergism in the therapy of gram-negative rod bacteremia. | To determine if antimicrobial synergism might affect the results of treatment of gram-negative rod infections, 444 bacteremias from 1972 through 1974 were studied. On these, 173 were treated with two antibiotics to which the infecting organisms were sensitive. Clinical responses were observed in 80% of 83 cases where a... | 412,648 | [
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0.409668,
... |
Epilepsy and folic acid. | With 15 cases of epilepsy as the subject, studies were made of the therapeutic effects of folic acid on psychiatric symptoms and clinical seizures. Folic acid proved effective for a part of chronic and prolonged psychiatric symptoms shown by epileptic patients and brought on slight improvement in hyperexcitability, agg... | 412,749 | [
-0.1999689,
0.2772586,
-0.1176651,
-0.3768941,
0.1923632,
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-0.1195555,
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0.1070425,
0.3386904,
0.2099938,
0.349584,
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0.06793079,
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0.08293016,
0.3898059,
0.03858589,
0.258259,
0.2783733,
-0.1023339,
-0.... |
Polygraphic study on the clinical seizures induced during nocturnal sleep. | The subjects of this study consisted of 17 epileptic patients with clinical seizures during all-night sleep recording (the seizure group) and another 17 epileptic patients without clinical seizures (the control group). The results obtained were as follows: 1) The 50-90% out of total clinical seizures were induced in no... | 412,751 | [
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0.01393375,
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0.02308686,
0.1708986,
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0.3298908,
0.001686332,
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0.09957965,
0.5078839,
0.4521387,
-0.08830069,
0.119227,
0.450759,
-0.05138966,
... |
[The behavior of prealbumin, retinol binding protein and the immunoglobulins during 3 weeks of nutritional rehabilitation]. | A significant improvement in the protein status of twelve malnourished geriatric patients was achieved during a three-week daily supplementation of the hospital diet by 9 g essential amino acids (eight classical essential amino acids plus histidine). This was especially evident in the doubled serum concentration of pre... | 412,785 | [
0.00809463,
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0.004491245,
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0.3033693,
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0.2964209,
0.005181828,
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0.06115232,
-0.3867786,
0.09615128,
-0.02279774,
0.04252133,
0.1578... |
Cellular immunity to bacteria: impairment of in vitro lymphocyte responses to Pseudomonas aeruginosa in cystic fibrosis patients. | Lymphocyte responses to the mitogens phytohemagglutinin and concanavalin A and to Streptococcus pyogenes, Staphylococcus aureus, Haemophilus influenzae, and Pseudomonas aeruginosa were evaluated in patients with cystic fibrosis and in normal individuals. Lymphocyte proliferation in vitro was stimulated by gentamicin-ki... | 412,789 | [
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0.2864922,
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0.1077168,
0.2549627,
0.08478772,
0.1815682,
-0... |
A precipitate adsorption on surface technique: a combination of immunodiffusion and thin-layer immunoassay. | A new technique--precipitate adsorption on surface--is described. The technique implies a combination of immunoprecipitation in gel and diffusion-in-gel-thin-layer immunoassay. The principles of the technique are illustrated by a series of model experiments. | 412,796 | [
-0.01629492,
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0.2210793,
0.408204,
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-0.09438436,... |
Postoperative jaw pain--floctafenine versus dihydrocodeine. | A double-blind single dose trial was made of floctafenine 200 mg versus dihydrocodeine 30 mg in 100 patients complaining of jaw pain following oral surgery under general anaesthesia. There was no statistical difference between the two analgesics for the whole group, but dihydrocodeine was better for the relief of more ... | 412,800 | [
-0.2842415,
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0.2379303,
0.1282652,
0.06850884,
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0.2323131,
-0.05218086,
... |
A simplified model for teaching minor oral surgery. | A teaching model, specially constructed for the purpose of training senior dental students in the use of surgical instruments, is described. The advantages of this model are inexpensiveness and reproducible simulated surgical situations securing a uniform teaching objective. | 412,805 | [
-0.1287248,
-0.07514913,
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-0.1701731,
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0.4463646,
-0.1373035,
-0.01... |
Radioimmunoassay for antigliadin-antibodies using 14C-labelled gliadin. | A sensitive radioimmunoassay for antibodies to gliadin has been developed. Gliadin from wheat gluten was labelled with [1-14C]acetic anhydride to a specific activity of 2.6 X 10(6) dpm/mg. Immunological evidence is presented that the antigen was not essentially altered by the labelling procedure. Experimentally-induced... | 412,899 | [
-0.2980073,
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0.3711759,
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0.193266,
0.265474,
0.132689,
-0.2398478,
-0.02300... |
The relation of lipids to the mineral components in salivary calculi. | Using lipid histochemical and microradiographic methods, the distribution of lipids and the inorganic component in different areas of salivary calculi was investigated. Two main groups of lipids were found, i.e. hydrophilic phospholipids and hydrophobic lipids. The hydrophilic phospholipids were shown to be composed ma... | 412,930 | [
0.03996873,
0.2806411,
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0.3717706,
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0.1564354,
0.1973187,
0.1780445,
0.4374007,
0.1425097,
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0... |
Plasma somatomedin and growth hormone values in children with protein-calorie malnutrition. | This study was undertaken to define the interrelationships of somatomedin, growth hormone, and an inhibitor of SM in protein-calorie malnutrition. Twenty-seven patients, eight to 60 months of age, were studied. Twenty-one well-nourished children acted as controls. SM was significantly depressed at Days 2 and 8 (p less ... | 412,936 | [
-0.231607,
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0.1053616,
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0.354817,
0.0990119,
0.1652449,
-0.1671194,
... |
Potential inhibitors of collagen biosynthesis. 5,5-Difluoro-DL-lysine and 5,5-dimethyl-DL-lysine and their activation by lysyl-tRNA ligase. | The synthesis of lysine analogues wherein blocking groups are substituted at position 5, the site of hydroxylation by peptidyl lysine hydroxylase, is described. Thus, 5,5-difluorolysine (1) and 5,5-dimethylysine (2) were synthesized via a four- and six-step sequence, respectively, starting from ketone precursors. The p... | 412,965 | [
-0.3202677,
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0.09285296,
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0.01045154,
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0.2013517,
0.4190951,
0.06679656,
-0.0689129,
... |
Variant of iduronidase deficient mucopolysaccharidoses: further evidence for genetic heterogeneity. | An alpha-L-iduronidase deficiency syndrome has been described in adult male twins, which was phenotypically distinct from that of the Hurler and Scheie syndromes or the chondroitinsulphaturias. Multiple dysostosis and stiff joints were present without cloudy corneae, cardiac involvement and mental or physical retardati... | 412,969 | [
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0.335921,
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0.2779262,
0.4346464,
0.4114704,
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0.05638337,
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-0.5578223,
-0.1898419,
-0.08743264,
-0.2359672,
0.1594427,
0.02070674,
-0.135070... |
The unique kidney of the spider monkey (Ateles geoffroyi). | Among nonhuman primates, the renal anatomy of the spider monkey (Ateles geoffroyi) is unique, as it is multipyramidal and multipapillary. Renal function parameters (glomerular filtration rate, renal plasma flow, and concentrating ability) are compared to man and other primates. The kidneys of the spider monkey are simi... | 412,972 | [
0.1285629,
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-0.3343357,
0.05159687,
0.06670476,
-0.311734,
-0.4530793,
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-0.05899237,
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-0.07068197,
-0.01305113,
0.113904,
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0.2888204,
-0.08095769,
-0.1753879,
0.1387615,
0.2061026,
-0.0469113... |
[Hospital infections from a bacteriological viewpoint]. | In spite of the successful treatment of bacteriological infections combined with progress in hospital hygiene there remain still problems of infective hospitalism in certain sections of the hospital. Generally, the causative bacteria are nosoparasites not being dangerous to human beings in good condition. From this poi... | 412,996 | [
0.087406,
-0.1473705,
-0.07440668,
0.1794527,
0.119865,
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0.1306851,
0.09681814,
0.1884087,
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0.0119273,
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0.05403505,
0.2021587,
0.001092068,
-0.05042782,
0.02926396,
0.2241831,
... |
The duration of gestation in the squirrel monkey (Saimiri sciureus). | A restricted mating period was used to determine the duration of gestation in the squirrel monkey (Saimiri sciureus) of Colombian-Brazilian origin. Ten pregnancies were observed. The length of the gestation period was found to range from 141 to 154 days with a mean of 146.9 +/- 3.28 SD, a median of 146.5, and a modal l... | 413,002 | [
0.1318887,
-0.1109293,
-0.1061639,
0.02785304,
0.1970483,
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0.2029743,
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0.03960907,
0.09405814,
-0.1057016,
-0.1446318,
0.05571035,
0.145403... |
The olive babbon (Papio anubis) as an animal model for research in affective disorders of man. | Efforts were made to develop an animal model for studies of the role of biogenic amines in a group of human "mood" diseases including mania and depression. Subadult, male olive baboons (Papio anubis), both normal and psychologically disturbed individuals, were anesthetized and administered 18O-enriched air for 60-130 m... | 413,003 | [
-0.1607466,
-0.04356547,
-0.2423234,
0.03219151,
0.01561582,
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0.03328993,
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0.03669199,
-0.06981961,
0.2563087,
0.234484,
0.4762302,
-0.1066208,
... |
Plantar ulcers with osteomyelitis underneath. A bacteriological study. | 39 consecutive cases of plantar ulcers with underlying chronic osteomyelitis admitted in the Sacred Heart Hospital during 1975/1976 were studied for the infecting organisms and their sensitivity to easily available antibiotics. Single organism was iasolated in only 10 cases, the infection in the rest being a mixed one.... | 413,005 | [
0.05046648,
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0.05497526,
0.2573407,
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0.2145107,
0.1806844,
0.06773085,
0.136334,
0.2... |
Cytological analysis of X-ray-induced aberrations in spermatocytes I and the somatic ganglia of male Drosophila melanogaster. | The correlation between damage induced in somatic cells and that induced in germinal cells of the same genetic pool of individuals is important in establishing the possibility of extrapolation of this damage to the offspring. We have used Drosophila melanogaster to compare cytologically the frequency of aberrations ind... | 413,031 | [
0.1849501,
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0.1639951,
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0.2557012,
0.221969,
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0.02422446,
0.1853194,
0.1577188,
0.2779726,
0.159953,
0.009272374,
-0.17... |
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