title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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The relationship between stem cell seeding efficiency and position in cell cycle. | The seeding efficiency of colony-forming cells from normal, regenerating and velocity-sedimented cycling and non-cycling narrow preparations was compared. Colony-forming cells in cycle were found to exhibit a 50% reduction in splenic seeding when compared to normal marrow or sedimented non-cycling cells. The results of... | 427,876 | [
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Mode of action of formamidine pesticides: an evaluation of monoamine oxidase as the target. | The ability of formamidine pesticide, chlordimeform (N'-(4-chloro-o-toyl)-N,N-dimethylformamidine) (CDM), and several of its major metabolites to inhibit monoamine oxidase (MAO) in mouse tissues in vitro and in vivo was examined, and related to the hypothesis that inhibition of MAO is responsible for the lethal effects... | 428,001 | [
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Fate of juvenile hormone in mammalian cell culture. | The metabolism of juvenile hormone (JH) I has been examined in fetal mouse liver cells maintained in culture. Diffusion of the hormone into the cells appears to be passive. The hormone is metabolized essentially to organic-soluble metabolites (diol ester, diol acid and acid) by the action of epoxide hydrase and carboxy... | 428,008 | [
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The role of adenosine in prolonged vasodilation following flow-restricted exercise of canine skeletal muscle. | A period of prolonged vasodilation follows flow-restricted exercise of skeletal muscle. We tested the hypothesis that adenosine participates in mediating this vascular response. Vascularly isolated, anterior calf muscles of anesthetized dogs were stimulated to contract at a rate of 4 twitches/sec. Blood flow was held c... | 428,070 | [
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Acceleration of idioventricular rhythms by histamine in guinea pig heart: mediation by H2 receptors. | To evaluate the ability of histamine to induce ventricular arrhythmias, we studied the effects of histamine on ventricular rhythmicity in the isolated guinea pig heart with complete atrioventricular conduction block. As a function of dose (0.1-30 microgram), histamine enhanced the idioventricular rate by increasing the... | 428,077 | [
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Usefulness and limitations of thallium-201 myocardial scintigraphy in delineating location and size of prior myocardial infarction. | In order to evaluate the usefulness of thallium-201 (201TI) myocardial scintigraphy in delineating the location and size of prior myocardial infarction, 32 patients were evaluated at a mean of 7 +/- 2 months after infarction with a 12-lead ECG, resting 201TI myocardial scintigram, biplane left ventriculogram and corona... | 428,082 | [
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Congenital coronary arteriovenous fistula. Report of 13 patients, review of the literature and delineation of management. | Thirteen new patients and 174 patients previously reported with coronary arteriovenous fistula (CAVF) were reviewed to delineate the course and management of CAVF and to clarify the role of surgical ligation in the young asymptomatic patient. Patients were grouped according to age: 99 patients (four new and 95 reported... | 428,095 | [
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Antiarrhythmic drug therapy in survivors of prehospital cardiac arrest: comparison of effects on chronic ventricular arrhythmias and recurrent cardiac arrest. | We studied the long-term effects of membrane-active antiarrhythmic agents on chronic ventricular arrhythmias in patients who have survived prehospital cardiac arrest. Among 16 patients treated with a dose-adjusted, plasma level-monitored antiarrhythmic regimen, eight have survived for longer than 12 months and eight ha... | 428,096 | [
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The cardiac conduction system in situs ambiguus. | The cardiac specialized conduction tissue was studied by serial sectioning in 13 cases of situs ambiguus. In four cases of right isomerism, we found paired sinus nodes in relation to a crista terminalis, and in each case a sling of conduction tissue between two atrioventricular nodes was present regardless of the ventr... | 428,099 | [
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Autonomic dysfunction in women with mitral valve prolapse syndrome. | Autonomic cardiovascular regulation was evaluated in 35 women, 19 with mitral valve prolapse and 16 healthy controls. Heart rate responses to the diving reflex and to phenylephrine infusion were diminished in patients. Noninvasive measures of cardiac output, heart rate, blood pressure, forearm flow and leg volume durin... | 428,102 | [
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Circadian variation of exercise capacity in patients with Prinzmetal's variant angina: role of exercise-induced coronary arterial spasm. | Thirteen patients with Prinzmetal's variant angina performed treadmill exercise tests in the early morning and in the afternoon of the same day. The attacks with ST elevation were induced repeatedly in all 13 patients in the early morning, but in only two patients in the afternoon. Propranolol did not suppress the exer... | 428,106 | [
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Quantitative left ventricular wall motion analysis: a comparison of area, chord and radial methods. | We were interested in divising a relatively simple quantitative technique that could be used on a routine clinical basis for wall motion analysis. Three quantitative methods of left ventricular (LV) regional analysis were compared in the 30 degrees right anterior oblique and 60 degrees left anterior oblique projection.... | 428,111 | [
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Effect of age on plasma androstenedione concentration in oophorectomized women. | Plasma androstenedione concentration was measured in 92 oophorectomized women in the age range 33 to 76 years. Although this concentration was significantly inversely correlated with age, the data suggest a discrete change in the first half of the sixth decade rather than a continuous fall. | 428,117 | [
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Outcome of adopted Vietnamese children. Beneficial effects of a normal home environment on 36 children. | Thirty-six adopted Vietnamese children were evaluated physically and developmentally from four months to ten years after their adoption. All of the children had experienced early months of malnutrition, disease and deprivation. Many of the children were adopted before their first birthdays and received continuous, adeq... | 428,175 | [
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The prevalence of middle ear disease among learning impaired children. Does a higher prevalence indicate an association? | The prevalence of middle ear disease among children who are educationally classified as learning disabled as compared to that found in normal children is discussed. A higher incidence of middle ear pathology was found among the learning impaired children. The potentially hazardous effects that middle ear disease can ha... | 428,178 | [
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Combined and national experience of postmenstrual IUD insertions of Nova-T and Copper-T in a randomized study. | A randomized comparative study between Nova-T and Copper-T-200 was performed simultaneously in Denmark, Finland and Sweden. The results of 741 postmenstrual insertions with Nova-T and 780 with Copper-T are reported. The pregnancy rate of Nova-T was lower in every age and parity group. The pregnancy rate of Copper-T-200... | 428,220 | [
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Serum prolactin levels in short-term and long-term use of inert plastic and copper intrauterine devices. | Serum prolactin values were assessed in 59 normally menstruating parous women; groups were divided with respect to short-term (6 weeks) and long-term (4-60 months) use of either the inert plastic IUD (Saf-T-Coil or Lippes Loop) or copper IUD (Cu-7). Preinsertion values served as controls in the short-term study while a... | 428,221 | [
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Induction of mid-term abortion by trichosanthin in laboratory animals. | Trichosanthin, a protein purified from the extract of the root tuber of Trichosanthis Kirilowii, Maxim, given once only induced midterm abortion in the mice and rabbits. The effective I.P. dose for the induction of abortion in 10- or 11-day pregnant mouse was 50 micrograms. In the rabbit a dose and state of pregnancy-d... | 428,233 | [
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Indian experience with a single long-acting vaginal suppository for the termination of pregnancies. | The Indian Council of Medical Research conducted a multicentric trial with a single vaginal suppository containing 3 mg 15-Me-PGF2 alpha for terminating pregnancies. Success rate in the 290 women investigated was 79.2 per cent at 30 hours observation. The mean induction-abortion interval was 14.7 hours and the incidenc... | 428,234 | [
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Outward bound: a treatment modality unexplored by the social work profession. | The Outward Bound Experience has a strong yet time-limited impact on delinquent youths. Social workers could help maintain the impact by establishing community-based followup programs that would reinforce and sustain the positive attitudes and behaviors developed. | 428,259 | [
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Studies in heterochromatin DNA: accessibility of late replicating heterochromatin DNA in chromatin to micrococcal nuclease digestion. | Heterochromatin DNA in cactus mouse (Peromyscus eremicus) replicates in the late S phase of cell cycle. A method of obtaining cells which contain DNA preferentially labeled at heterochromatic areas by a pulse-labeling of late replicating DNA is described. When the nuclei of P. eremicus cells containing radioactively la... | 428,268 | [
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[Skateboards: a dangerous toy? (author's transl)]. | Eighteen persons (average age 12.4 years) with injuries from skateboard accidents were admitted between 1 March to 5 June, 1977--4.4% of all accidents and 7.5% of all sports accidents treated during this interval. These kinds of accidents are now in fourth place as to frequency, after accidents during play (81), bicycl... | 428,326 | [
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Endoscopic duct obstruction in chronic pancreatitis. | Ligation of Wirsung's duct or obstruction with a glue may be an alternative to pancreatectomy in patients with intractable pain due to chronic relapsing pancreatitis. In 10 patients obstruction of Wirsung's duct was performed via endoscopic retrograde instillation of an alcoholic aminoacid solution into the ductal syst... | 428,351 | [
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Body composition of the horse. | Seventeen horses were dissected and their organs and tissues weighed. The results of these dissections are presented together with comparisons of the data with that already available in the literature. Predictive equations for organs and tissue weights are also given which were derived by comparison of linear and allom... | 428,363 | [
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Singlet oxygen formation by a peroxidase, H2O2 and halide system. | Evidence for singlet oxygen formation has been obtained for the lactoperoxidase, H2O2 and bromide system by monitoring 2,3-diphenylfuran and diphenylisobenzofuran oxidation, O2 evolution, and chemiluminescence. This could provide an explanation for the cytotoxic and microbicidal activity of peroxidases and polymorphonu... | 428,384 | [
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Binding of oligonucleotides to the disk of tobacco-mosaic-virus protein. | The trinucleoside diphosphate A-A-G and the hexanucleotide fraction from a ribonuclease I digest of yeast RNA have been soaked into crystals of the disk aggregate of tobacco mosaic virus protein. At high concentrations these cause disruption of the crystal, probably by mimicking the normal nucleation of assembly. At lo... | 428,385 | [
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Metal ion/buffer interactions. Stability of binary and ternary complexes containing 2-amino-2(hydroxymethyl)-1,3-propanediol (Tris) and adenosine 5'-triphosphate (ATP). | The interaction of 2-amino-2(hydroxymethyl)-1,3-propanediol (Tris) with the metal ions (M2+) Mg2+, Ca2+, Ba2+, Mn2+, Co2+, Ni2+, Cu2+, Zn2+, Cd2+, and Pb2+ was studied by potentiometry and spectrophotometry in aqueous solution (I = 0.1 or 1.0 M, KNO3, 25 degrees C). Stability constants of the M(Tris)2+ complexes were d... | 428,398 | [
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Resorptive and absorptive hypercalciuria. Therapy with sodium cellulose phosphate or thiazides. | Patients with recurrent stone disease and hypercalciuria were cleared up according to Nordin's schedule. In cases of absorptive hypercalciuria, an ion exchanger operating in the intestine, sodium cellulose phosphate (SCP), is applied under strict control of oxalate, calcium and magnesium excretion as well as ionized ca... | 428,408 | [
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0.1555697,
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Effects of L-dopa on putrescine levels in the brain and the liver of the rat. | The pharmacological effects of several amino acid precursors of putative neurotransmitters on putrescine levels in the brain and the liver of the rat were studied. L-dopa increased brain and liver putrescine levels in a dose-dependent manner that reached its maximum effect in 4-6 h. The increase in liver putrescine was... | 428,424 | [
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Effects of baclofen on striatal 5-HT mediated by the nigrostriatal dopamine system. | In rats, baclofen injected unilaterally into the substantia nigra increased dopamine (DA) and serotonin (5-HT) levels in the ipsilateral striata. Homovanillic acid levels first decreased and then increased to a maximum after 4 h. The content of 3,4-dihydroxyphenylacetic acid also increased after a latency of about 1 h.... | 428,427 | [
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Enhancement of erythroid colony growth in culture by hemin. | Hemin was found to enhance the growth of murine erythroid colonies in culture. In the presence of 100 mU/ml erythropoietin (EPO), the addition of hemin (0.05-0.2 mM) resulted in the growth of twice as many colonies as were obtained with EPO alone. Hemin also significantly increased erythroid colony formation in culture... | 428,474 | [
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Biotransformation of drugs during aging. | Although the biological half-lives of many drugs appear to be longer in the elderly than in the young, the reasons for these longer half-lives are seldom clear, because the pharmacokinetic data obtained in humans are seldom sufficient to make a proper pharmacokinetic analysis. In the present paper are outlined the kind... | 428,574 | [
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Carbohydrate and lipid studies in women using the progesterone intrauterine device for one year. | Carbohydrate and lipid metabolism was evaluated in 31 women before and after 1 year's use of a progesterone-releasing intrauterine device. The studies involved measuring blood glucose and plasma insulin levels during a 3-hour oral glucose tolerance test and also measuring fasting cholesterol and triglyceride levels. Th... | 428,580 | [
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Steroid receptor levels and histology of endometriosis and adenomyosis. | Steroid receptors in endometriosis and adenomyosis were investigated to clarify their clinical significance. The receptor levels were determined by Scatchard plot analysis (4 degrees C, by dextran-coated charcoal). In the cytosols of both tissues, the 17 beta-estradiol-estrogen receptor (ER) complex demonstrated a diss... | 428,583 | [
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Pancreatic polypeptide. Metabolism and effect on pancreatic secretion in dogs. | In dogs with gastric and pancreatic fistulas, porcine pancreatic polypeptide (PP) was infused intravenously in doses of 50, 100, 200, 400, and 800 pmol kg-1 hr-1 in the basal state and in doses of 100, 200, and 400 pmol kg-1 hr-1 during stimulation with submaximal doses of secretin (125 ng kg-1 hr-1) plus caerulein (50... | 428,706 | [
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A new site-specific endonuclease from Streptomyces lavendulae (SlaI). | A new restriction-like endonuclease, SlaI, was found and partially purified from Streptomyces lavendulae ATCC8664. This endonuclease cleaved bacteriophage lambda DNA at only one site, and cytosine-substituted bacteriophage T4 DNA at 16 sites. The recognition sequence was determined by using SlaI fragments of cytosine-s... | 428,725 | [
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Influence of age and spironolactone on lysosomal enzyme activities, DNA and protein content of the rat liver after partial hepatectomy. | Measurements of DNA and protein content and determinations of lysosomal enzyme activities (beta-glucuronidase, beta-acetylglucosaminidase, cathepsin D) were performed in the rat liver following partial hepatectomy and spironolactone administration. The rats (SIV) were divided into three age-groups: 6 weeks old, 10 mont... | 428,739 | [
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Serum bilirubin: a prognostic factor in primary biliary cirrhosis. | We followed up 55 patients with proven primary biliary cirrhosis for several years or until death. A graph of the level of serum bilirubin versus time that was constructed for each patient shows an initial period of variable length in which the serum bilirubin level remained constant. This was followed by a period of r... | 428,825 | [
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Rectal IgE cells in inflammatory bowel disease. | Immunoglobulin-contained cells in the rectal mucosa of patients suffering from non-specific inflammatory bowel disease (IBD) were counted and compared with those in a control population. While the numbers of IgA, IgM, and IgG-containing cells in both ulcerative colitis and Crohn's disease did not differ from normal, bo... | 428,827 | [
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... |
[Long lasting psychotropic effects after long-term treatment with a hemoderivative]. | Up to now there has been scarcely any publication of precise tests on the duration (lasting effect) of psychotropical effects which have appeared in brain activity after conclusion of a longterm therapy with vasoactive or metabolical substances. In 32 patients with symptoms of arteriosclerosis (average 72 years) a six ... | 428,840 | [
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[Regeneration of the gastric and intestinal mucosas]. | The physiological cell renewal of gastrointestinal mucosa is regulated in man as in animal through certain mechanisms with measurable kinetic data. Pathologic mucosal alterations, metabolic disorders, pharmacological agents etc. clearly affect the regenerative processes of the gastrointestinal epithelium. Gastrin and p... | 428,851 | [
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... |
[Nystagmus as a diagnostic criterium in neurology]. | The most frequent seen nystagmus is jerk nustagmus. It is a versional eye movement comprising a quick and a slow phase. For diagnostic reasons it is very important to know the connections involved in vestibulo-oculomotor control. Besides peripheral, labyrinthine disturbances the observation of nystagmus is a very good ... | 428,874 | [
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[Measurement and evaluation of industrial noise]. | Different methods for measurement and assessment of industrial noise are discussed. It is shown, that momentary the best approach to stress caused by noise is the "Trakt-Maximalpegel-Verfahren" with a cycle time of 5 s. For more exact description of acoustic recording of sound level and harmonic analyzis are indispensa... | 428,875 | [
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The use of perfused rat intestine to characterise the glucagon-like immunoreactivity released into serosal secretions following stimulation by glucose. | Isolated perfused intestine of rat was used to demonstrate the glucose-stimulated release of glucagon-like immunoreactivity (GLI) into serosal secretions. The released GLI was characterised using immunoaffinity chromatography on columns of immobilised antibodies specific for the N (residues 1 to 18) and for the C (resi... | 428,905 | [
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NIH panels analyze issues on technology. | Experts at NIH's "consensus development" technology assessment conferences study a wide range of issues and make recommendations to help guide users of medical technologies. | 428,935 | [
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Buerger's disease involving the celiac artery. | A young male with Buerger's disease who had previously required a left leg amputation died in renal failure and sepsis. Postmortem examination revealed an obliterative lesion of the celiac artery, which resulted in hepatic, splenic, and pancreatic infarctions. Celiac artery involvement represents an unusual manifestati... | 428,990 | [
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Ultrastructure of benign cartilaginous tumors of intraosseous origin. | The ultrastructure of chondroblastoma, chondromyxoid fibroma, and enchondroma is described. In chondroblastoma the tumor cells often show nuclear indentations and a thick nuclear fibrous lamina, and have features indicative of poorly differentiated cartilaginous cells. Chondroblastoma is a tumor thought to arise from i... | 428,995 | [
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Langer type of mesomelic dwarfism as the possible homozygous expression of dyschondrosteosis. | A male newborn with the typical Langer type of mesomelic dwarfism is presented. The finding of a variable degree of Madelung's deformity and mesomelic shortening in both parents and in the maternal family tends to support the hypothesis that this type of mesomelic dwarfism may be the clinical manifestation of a homozyg... | 429,003 | [
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Comparison of Bungarus caeruleus venom with the venom from which a putative cholinergic ionophore marker was isolated. | Comparisons are described between Bungarus caeruleus venom and the actual venom from which a putative marker for the cholinergic ionophore, called ceruleotoxin, was isolated. The venoms are shown to be different by two procedures for ion exchange chromatography and by isoelectric focusing on polyacrylamide gel. The act... | 429,091 | [
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Spatial periodicities of periodic complex cells in the visual cortex cluster at one-half octave intervals. | Within individual penetrations in the visual cortex, spatial periodicities of periodic complex cells differ by either one-half or one octave. When data are pooled from neurons subserving the central visual area in many cats, the results indicate that spatial periodicities cluster at one-half octave intervals over a 2 1... | 429,116 | [
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Cryoprecipitate: its use and effects in canine coagulum pyelolithotomy. | A fibrin clot forming an extractable cast or "coagulum" of the pyelocalyceal system was developed and characterized using a blood product not previously described--single donor type specific cryoprecipitate. The physical properties of the cryoprecipitate coagulum were investigated and compared with other described form... | 429,117 | [
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The synthesis and release of prostaglandins by human urinary bladder muscle in vitro. | Using the technique of bioassay the presence, production, and importance of prostaglandins (PG) in human bladder muscle have been investigated in vitro. Low basal tissue levels of PG were shown. E series PGs were released by isolated bladder muscle strips in organ bath experiments. The spontaneous activity and PG relea... | 429,129 | [
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... |
The Nb rat: prostatic adenocarcinoma model. | The Noble rat prostatic adenocarcinoma is an animal model which is used to study human prostatic carcinoma. It mimics the human condition in histology, in biochemistry with the production of acid phosphatase, and in tumor growth which is relatively constant. Additionally, it is hormonally dependent and metastasizes. Th... | 429,131 | [
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The ultrastructural effect of distension on the neuromuscular apparatus of the urinary bladder. | The recent clinical success of distension therapy in the treatment of idiopathic detrusor hyperreflexia has prompted this ultrastructural study. The neuromuscular pathways of conduction in the rat and rabbit urinary bladder wall were examined using perfusion fixation techniques. The effects of short-term and prolonged ... | 429,133 | [
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Formation of cross-linked molecules during vaccinia DNA replication. | The appearance of cross-linked DNA molecules during the replication of vaccinia virus DNA was investigated. Conversion of full size DNA molecules to cross-linked molecules occurs several hours after completion of DNA synthesis. Inhibition of RNA synthesis by actinomycin D did not prevent this transition; however, inter... | 429,148 | [
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[Necrosis of the lesser curve of the stomach after proximal selective vagotomy]. | Necrosis of lesser curve of stomach after proximal selective vagotomy is a specific but rare hazard of this operation. Anatomical and pathophysiological findings speak in favour of ischaemic pathogenesis, even if a peptic factor may exceptionally play a role in some cases. Local tissue trauma enhances the risk of later... | 429,161 | [
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-0.1114033,
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0.2468029,
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0.008776827,
0.05605615,
0.2303155,
-0.2121283,
0.0629824,
-0.414158,
-0.14743,
-0.1764485,
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0.03108029,
0.1358075,
0.01134291,
0.510102,
0.2105115,
-0.1654675,
0.... |
[Superselective parathyroid hormone determination--a reliable diagnosis of the location of endocrinological active parathyroid neoplasms]. | The importance of superselective catheterization of the small jugular veins for PTH-radioimmunoassay is shown as an improvement of the preoperative localization technique. Since May 1976 in 20 patients the diagnosis of pHPT could be established. Our own experiences with the method of small vein sampling combined with t... | 429,177 | [
-0.01381363,
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0.2550912,
0.6566458,
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0.... |
[The combination of fractures of the lower extremity and lesion of the posterior cruciate ligament]. | In 400 fractures of the upper and lower leg, 7 patients had an additional lesion of the posterior cruciate ligament. This combination occurs in people, who had a high energy frontal impact in the sitting position. The ligamenteous injury is often overlooked because of multiple injuries and difficulty in examination of ... | 429,186 | [
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0.1524964,
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0.1360729,
... |
[Turning-point of the bowel preparation?]. | The whole-gut irrigation more and more carries through to be a favourite method for preoperative large bowel preparation. In 1975 it was used only by 3 hospitals in Switzerland, which resulted from our investigations about large bowel preparation. This new procedure brings advantages such as complete cleaning of the ga... | 429,190 | [
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0.2193739,
0.0308780... |
[Renal lesions in congenital syphilis. A case report]. | The authors describe a case of congenital syphilitic nephropathy in an infant. The review of the reports in the literature shows many similarities of this congenital disease with the syphilitic nephrotic syndrome in the adult. The prognosis is favorable provided the diagnosis is made sufficiently early. Histological st... | 429,197 | [
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0.3362744,
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Histochemical and atomic absorption demonstration of trace metal mobilization in the central nervous system and liver of the rat. | Histochemical and atomic absorption spectrophotometric analysis of trace metal mobilization caused by the action of ethanol in the central nervous system (CNS) and liver of the rat is described. Histochemically it has been shown that in all neurons examined (motoneurons, pyramidal and Purkinje cells) the trace metals (... | 429,206 | [
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0.1845044,
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0.4346296,
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Studies on the molecular arrangement of RNA in tissues with a selective topo-optical reaction of RNA. | Selective demonstration of RNA in tissues was achieved by treating tissue sections with potassium permanganate followed by bisulfite and toluidine blue at pH 1.0 (PBT reaction). It is suggested that this reaction is due to aldehyde groups which are formed by the oxidative cleavage of the pyrimidine rings of RNA which c... | 429,208 | [
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0.1290584,
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... |
[Aquamat--a proven bathing aid for the laryngectomee (author's transl)]. | A device to facilitate bathing by the laryngectomee is described. The Aquamat is made up of equipment routinely used in anaesthesia and underwater diving. An airway link is made between a watertight tracheostoma and the mouth such that the patient can breath between nose and trachea. Special precautions are necessary f... | 429,216 | [
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0.2961898,
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Comparative studies on actins from various sources. Fragments of actins from Ascaris muscle cleaved at cysteinyl residues in comparison with those of other actins. | Pure actins were obtained from various animal muscles: Vertebrata (skeletal, smooth, and cardiac muscles), Prochordata (smooth muscle), Nematoda (obliquely striated muscle), and Mollusca (striated, smooth and obliquely striated muscles). These actins were all identical in apparent molecular weight on sodium dodecyl sul... | 429,256 | [
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0.4675879,
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Purification and properties of cytochrome b-562.5 from Ulva pertusa. | Cytochrome b-562.5 (Ulva pertusa) was extracted from a green alga, U. pertusa, by homogenization of the thalli in phosphate buffer solution. Purification was carried out by acrinol treatment, ammonium sulfate fractionation, DEAE-cellulose and DEAE-Sephadex column chromatographies, and Sephadex gel filtration. Cytochrom... | 429,258 | [
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0... |
The export of glutathione from human diploid cells in culture. | The export of glutathione from cultured human diploid fibroblasts into the surrounding medium was found by isotopic labeling experiments using [35S]cystine and by enzymatic measurements. The major part of the glutathione exported from the cells was found in normal culture medium as mixed disulfide of glutathione and cy... | 429,361 | [
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Solution treatment behavior of Co-Cr-Mo alloy. | Current practice in the manufacture of Co-Cr-Mo alloy total hip prostheses is the use of a solution treatment to increase the ductility of the as-cast alloy. This study is concerned with the reactions encountered during solution treatment at temperatures between 1165-1270 degrees C. These reactions, including incipient... | 429,394 | [
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... |
Degenerative arthritis of the ankle secondary to long-standing lateral ligament instability. | Long-standing lateral ligament instability of the ankle results in unbalanced loading of the medial joint space and the possible development of degenerative arthritis. Thirty-six patients who had had lateral ankle instability for at least ten years and complaints of increasing ankle pain evidence degenerative changes o... | 429,402 | [
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Pressures generated in the thigh muscles and under the thigh cast of an uninjured subject wearing a cast-brace. | Intrinsic pressures within the thigh muscles of a normal subject were recorded with the subject in five different postures before and after application of a cast-brace. The extrinsic pressures between the plaster cast and the underlying skin also were recorded. The intrinsic muscle pressures were significantly increase... | 429,403 | [
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... |
Lipofibroma of the median nerve in the palm and digits of the hand. | Lipofibroma of the median nerve or its cutaneous branches is a rare benign tumor. The diagnosis is usually made at surgical exploration of a mass in the distal part of the forearm, the wrist, the palm, or the digits of the hand, which may be asymptomatic or associated with symptoms of carpal-tunnel syndrome. The diagno... | 429,410 | [
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Diastematomyelia in a geriatric patient. | The discovery of diastematomyelia in a geriatric patient is a rare occurrence. A 76-year-old woman with this entity was not diagnosed until she developed superimposed motor neuron disease. | 429,442 | [
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Variations in x-ray exposures to patients. | X-ray exposures to patients were measured in 30 rooms in Toronto hospitals. For a given procedure, the total exposure for a satisfactory examination differed from one room to another by as much as a factor of 30, skin exposures reaching 90 R and more for barium enemas and barium meals. The factors primarily responsible... | 429,443 | [
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... |
Osteoid osteoma in cancellous bone. | Osteoid osteoma in cancellous bone lacks the usual osteoblastic reaction that accompanies the classical cortical or juxtacortical osteoid osteoma. Familiarity with this type of presentation should instigate the appropriate diagnostic steps, including nuclear medicine studies using pin-hole collimation, and thin tomogra... | 429,444 | [
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0.249211,
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-0.0185... |
Coronary perfusion under general and selective cardiac hypothermia. | Experiments to assess left ventricular function in dogs during and after 2 hours of hypothermic cardioplegia are reported. During the experiment myocardial temperature was maintained between 15 degrees C and 18 degrees C by controlling the rate of flow of a cool cardioplegic solution into the coronary vessels. Before a... | 429,458 | [
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0.4765661,
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0.06196047... |
Effect of three serotonin antagonists on plasma prolactin response to suckling in puerperal women. | The effect of the acute administration of three serotonin antagonists on plasma PRL levels and on the PRL response to suckling was investigated in a group of puerperal women. A single oral dose of metergoline or methysergide induced a significant decrease of plasma PRL levels and abolished the PRL response to suckling.... | 429,487 | [
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0.08159766,
0.2631358,
0.1929041... |
Relationship of free and total calcium in hypercalcemic conditions. | An assessment of free and total calcium measurements was made in 691 patients with suspected hypercalcemia or disorders often associated with hypercalcemia. In 18.9% of the 1049 specimens analyzed from nine different patient groups, a different impression of hypercalcemia was obtained depending on whether the free or t... | 429,492 | [
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0.2... |
Comparison of physiological and pharmacological tests of growth hormone function in children with short stature. | We studied 30 short-statured children to investigate their 24-h integrated serum concentration of GH (ICGH) and its diurnal pattern and to compare this data with their responses to standard stimulation tests for GH release. Eight patients with normal stimulation tests had a mean (+/- SD) ICGH value of 8.0 +/- 3.8 ng/ml... | 429,525 | [
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0.407452,
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0.06288852,
-0.2120... |
Two forms of Staphylococcus aureus in blood of patients with staphylococcal sepsis. | Two distinctly different and stable forms of Staphylococcus aureus were isolated from the blood of each of two patients with staphylococcal sepsis. In each case, one form was hemolytic and the other nonhemolytic, although both had the same biochemical reactions, phage types, and antibiotic susceptibilities, and both we... | 429,538 | [
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Further studies of the frequency and significance of the Tgamma-chain of human fetal hemoglobin. | A further study of the Tgamma-chain in a variety of conditions has revealed its presence in the cord bloods of ethnic groups previously unstudied. Heterozygous newborn average 17-19% Tgamma-chain while the mean value in four presumed homozygotes was 31%. The Tgamma-chain is readily detectable in beta-thalassemia of var... | 429,552 | [
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0.2450728,
0.1493357,
0.2571709,
0.3614003,
-0.215313... |
Effect of atropine on vagal release of gastrin and pancreatic polypeptide. | We studied the effect of several doses of atropine on the serum gastrin and pancreatic polypeptide responses to vagal stimulation in healthy human subjects. Vagal stimulation was induced by sham feeding. To eliminate the effect of gastric acidity on gastrin release, gastric pH was held constant (pH 5) and acid secretio... | 429,555 | [
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0.2354288,
0.154379,
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-0.0796703,
0.06935325,
0.0713168,... |
Elevated 1,25-dihydroxyvitamin D plasma levels in normal human pregnancy and lactation. | Plasma 1,25-dihydroxyvitamin D levels are elevated in early pregnancy and continue to increase throughout pregnancy. They remain elevated postpartum in lactating women. The elevated levels probably represent a physiological response to increased calcium requirements. | 429,557 | [
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0.02678511,
0.0169089,
0.1972807,
0.5004618,
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Resting skeletal muscle membrane potential as an index of uremic toxicity. A proposed new method to assess adequacy of hemodialysis. | Electrochemical disturbances of skeletal muscle cells in untreated uremia are characterized by an increase in the intracellular sodium and chloride content, a decrease in intracellular potassium, and a low resting membrane potential. In this study, we have reexamined the foregoing and, in addition, have examined the ef... | 429,569 | [
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0.177898,
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0.3127677,
0.31567... |
Medical careers in pathology, 1977. | A survey has been made, mainly covering the second half of 1977, of career grade posts and senior training posts in pathology in the United Kingdom. The survey included all disciplines of pathology and all types of employment--National Health Service, medical school, and many others. The survey also examined the number... | 429,573 | [
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0.2440692,
0.3205964,
-0.06932263,... |
Cytohormonal patterns in mature and pre-term babies. | Comparison of cytohormonal patterns in full-term and pre-term babies of both sexes showed significant differences. At birth, irrespective of gestational age, both groups had high oestrogen levels, reflecting the maternal hormonal environment, but whereas the mature neonates were capable of metabolising and excreting th... | 429,578 | [
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0.2326333,
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0.08217898,
0.1359093,
0.1378644,
-0.4058371,
-0.2249179,
-0.1806619,
0.1875431,
-0.02704187,
-0.05041448,
0.2183738,
0.314699,
-0.01300054,
... |
Gas-liquid chromatographic measurement of lignocaine in small samples of canine myocardium after enzymatic digestion. | A method is described whereby lignocaine can be measured in small samples of canine myocardium. A proteolytic enzyme is used to digest the tissue, and the drug, together with an internal standard, is subsequently extracted into an organic solvent and measured by gas-liquid chromatography. The method is reproducible usi... | 429,588 | [
-0.3281392,
0.2839517,
-0.1746265,
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0.2233997,
0.2914785,
0.1162346,
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0.225287,
0.2919607,
0.2893175,
0.04537473,
0.08380932,
-0.2894456,
-... |
Plasma binding capacity for 25-hydroxy-vitamin D in the elderly. | Plasma 25-hydroxy-vitamin D (25-OHD) concentrations and 25-OHD binding capacities were measured in 14 elderly patients and in 14 young controls. Both 25-OHD concentrations and 25-OHD binding capacities were reduced in the elderly. In neither group, however, was there a significant correlation between 25-OHD binding cap... | 429,591 | [
-0.2169232,
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0.02764956,
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0.1057207,
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0.140846,
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0.005159658,
0.227321,
0.4469844,
0.05220672,
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0.01471366,
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0.3211116,
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0.4283858,
0.2393532,
0.4595277,
-0.1030356,
0.... |
Quality control trials of prothrombin time: an assessment of the performance in serial studies. | A series of collaborative exercises on the one-stage prothrombin time test involving hospitals in Britain and overseas was performed between 1972 and 1977. The British Comparative Thromboplastin (BCT) and the lyophilised test plasmas were issued from the National (UK) Reference Laboratory for Anticoagulant Reagents and... | 429,593 | [
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0.4496774,
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0.1448589,
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0.2336551,
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0.2252045,
0.185879,
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0.1104409,
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0.1461542,
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-0.1938409,
0.1447541,
-0.142593,
0.1553729,
-0.1338349,
-0... |
Language performance of stuttering and nonstuttering children. | This study investigated the syntactic and semantic language performance of typically dysfluent nonstuttering children, stuttering children, and highly dysfluent nonstuttering children. The three groups of children did not differ on Developmental Sentence Analysis scores. The stuttering and highly dysfluent nonstutterin... | 429,605 | [
-0.1994139,
0.08955069,
0.1394681,
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0.2271334,
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0.3419535,
0.18461,
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0.07828025,
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0.1351694,
-0.2075048,
-0.3485021,
0.1575041,
0.1438789,
-0.1383892,
-0.... |
Two modes of cutaneous reinnervation following peripheral nerve injury. | The return of sensation to the foot following sciatic nerve crush injury was analyzed behaviorally and electrophysiologically in the rat. Functional recovery begins within four days. Its early phase is accounted for by expansion of the functional distribution of intact neighboring fibers of the saphenous n. It occurs e... | 429,615 | [
0.05665283,
0.06012063,
-0.2495733,
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0.1240398,
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0.02291804,
0.08617942,
0.2039193,
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0.07892387,
-0.1262024,
0.07493883,
0.1874062,
0.188263,
0.1261438,
... |
The lateral cervical nucleus in the cat: anatomic organization of cervicothalamic neurons. | The morphology of the lateral cervical nucleus (LCN) and the organization of the cervicothalamic projection neurons were studied in cats which had received thalamic injections of horseradish peroxidase (HRP). The boundaries of the LCN were defined following very large thalamic (HRP injections. Roughly 92-97% of LCN cel... | 429,620 | [
0.01847393,
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0.009821655,
0.1768696,
0.2466216,
0.07124612,
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0.03658833,
0.1669073,
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0.2140662,
0.4624974,
-0.08812679,
0.008499717,
0.3682972,
0.064546... |
Gated cardiac scanning: canine studies. | Retrospective electrocardiograph gating of data from a rotating detector fan beam computed tomography system was employed to produce end systolic and end diastolic images of the beating heart in a series of normal and experimentally infarcted canines. The gating window was typically less than 20% of the cardiac cycle, ... | 429,623 | [
-0.3179333,
0.6067629,
-0.3535762,
-0.1816355,
-0.1877934,
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0.006462088,
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0.04247925,
-0.3270663,
-0.07798105,
-0.3658991,
0.00129257,
0.01821275,
-0.2544769,
0.02294598,
0.2336986,
-0.1573... |
Tartrazine and the prostaglandin system. | The effect of tartrazine on prostaglandin production was evaluated in several in vitro systems in order to elucidate the interrelationship between aspirin-sensitive asthma and tartrazine. Unlike the nonsteroidal anti-inflammatory drugs, tartrazine did not inhibit cyclooxygenase activity in sheep seminal vesicles, guine... | 429,706 | [
-0.003102045,
-0.04431597,
-0.3120188,
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0.07827962,
-0.03059318,
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0.1760664,
0.2251951,
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0.06707472,
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0.01950692,
0.0647479,
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0.1758679,
-0.4527212,
-0.05416869,
0.1345464,
0.1700554,
0.187295,
0.2525737,
-0.2001156,
... |
Simple primary tuberculosis in an elderly woman. | The diagnosis of primary tuberculous infection was made in a 78-year-old woman. The chest roentgenographic findings were remarkably similar to those often seen in children and adolescents with primary infection. Like the majority of adults with this entity, the patient was asymptomatic; the diagnosis was suspected epid... | 429,731 | [
-0.1562832,
-0.01680809,
0.03327264,
-0.09921889,
-0.05446809,
-0.1915548,
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0.1348716,
0.4515758,
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0.07194792,
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-0.1878956,
0.06256853,
-0.09695199,
0.01074036,
0.3236695,
0.2408792,
-0.0... |
Institutionalized older adults and their future orientation. | This study hypothesized: 1) that as the duration of institutional living increases, the future orientation of active older adults contracts; and 2) that this constriction in future temporal orientation means less opportunity for interaction in the institutional environment. To test the first hypothesis, 100 active fema... | 429,733 | [
-0.198292,
-0.00853663,
0.2501792,
0.1868909,
0.04937179,
-0.1500555,
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0.2060311,
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0.08347424,
-0.1932822,
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-0.3401003,
-0.1010753,
0.06495728,
-0.1369164,
0.1989552,
0.006529126,
-0.5434076,
-0.1157898,
0.2424905,
0.2985493,... |
The elderly patient in the coronary care unit. I. Acute myocardial infarction. | In a Coronary Care Unit (CCU) with no age barrier for admission, 21 percent of the patients admitted in 1976 were aged 70 or older. Myocardial infarction was documented in 55 of 130 elderly patients. The overall incidence of arrhythmias was similar to that for younger patients. The mean duration of stay in the unit an... | 429,735 | [
-0.1003346,
0.05954999,
-0.4435925,
-0.3806216,
0.02409591,
-0.06656319,
0.06966071,
-0.2652884,
-0.1443842,
-0.1081206,
0.1389276,
0.2034705,
-0.08122173,
0.103374,
-0.02919332,
-0.2667295,
-0.2614427,
0.3828723,
-0.1347758,
0.08440733,
0.391467,
-0.006208773,
0.1908078,... |
The elderly patient in the coronary care unit. II. Incidence and treatment of arrhythmias. | In 1976, 130 patients aged 70 or older were admitted to the Coronary Care Unit (CCU) at Toronto Western Hospital. Arrhythmias were noted in all but 24 percent. Digoxin was given to 53 patients, lidocaine to 24, propranolol to 28, and quinidine to 11. In 2 patients, cardioversion by direct current was required for supra... | 429,740 | [
-0.02522527,
0.2488711,
-0.6264622,
-0.08152933,
0.3339114,
-0.3776269,
0.1144231,
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-0.3064401,
-0.107013,
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0.4653622,
-0.1109852,
0.3580364,
0.08675931,
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-0.2608679,
0.2656911,
0.09494402,
-0.1420487,
0.2132949,
0.3431275,
0.07908229,
... |
Nosocomial klebsiellas. I. Colonization of hospitalized patients. | The colonization of patients by Klebsiella and several other gram-negative bacteria was studied in a hospital urological ward over a period of six months. Before and during the survey there was no evidence of an outbreak of nosocomial infection and multi-drug resistant strains of Klebsiella were not isolated. Klebsiell... | 429,785 | [
0.02656425,
0.04335563,
-0.3427835,
-0.06703632,
-0.1441596,
-0.4201498,
-0.3424651,
0.06247099,
-0.1341611,
0.1945631,
0.324384,
0.1172568,
-0.004755984,
0.2882379,
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-0.3715264,
0.2465237,
0.1371203,
0.02768909,
-0.05428408,
0.1049591,
0.262499,
... |
Laboratory induction and clinical occurrence of combined clindamycin and erythromycin resistance in Corynebacterium acnes. | Corynebacterium acnes strains cross-resistant to clindamycin and erythromycin were observed following long-term selection or mutagenic treatment in the laboratory. Similar strains were found among clinical isolates from patients using clindamycin or erythromycin topically in the treatment of acne vulgaris. Clindamycin ... | 429,800 | [
0.109863,
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-0.1417406,
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0.137607,
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0.07627624,
0.1781809,
0.1076236,
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0.2810443,
0.1093635,
0.1747344,
0.3218622,
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0.1501125,
-0.06920182,
0.08924381,
0.3736474,
0.379292,
0.05114738,
-0.1... |
[An experimental study on repair and restoration of gliding function of the injured flexor tendon of the finger. Part 6: A mode of vascularization of the grafted tendon within the pseudosheath (author's transl)]. | The so-called two-stage procedure has been used in the reconstructive surgery for the severely injured flexor tendon of the finger. However, only little has been known as to vascularity of the grafted tendon within the pseudosheath. In order to clarify this problem, a series of experimental studies were carried out usi... | 429,824 | [
-0.3170551,
0.3516428,
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0.1623992,
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0.04390769,
0.2308859,
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0.03652143,
0.1370344,
-0.5186557,
0.3305313,
0.311537,
0.08622611,
0.1413825,
... |
Spontaneous secretion from the dog small intestine in vivo. | Forty loops of small intestine in the dog were perfused under control conditions with a balanced electrolyte solution. Most of the loops absorbed sodium and water, but 10 loops were in a state of spontaneous intestinal secretion. Compared to absorbing loops, spontaneously secreting loops exhibited reduced values for lu... | 429,849 | [
-0.1617595,
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-0.2729678,
0.1698989,
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0.2545982,
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-0.6556219,
0.01572116,
-0.000124021,
-0.09783119,
0.05300708,
-0.03808868,
0.... |
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