title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Distribution of mental health professionals in the South: a research project. | The Southern Regional Education Board is carrying out a project to determine what factors influence the distribution of mental health professionals in the South and to develop recommendations for improving distribution. The project is concerned with four major aspects of distribution: alleviating geographic maldistribu... | 488,934 | [
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A state perspective on psychiatric manpower development. | When the shortage of qualified psychiatrists and other physicians in Ohio's mental institutions reached the critical point in 1975, a number of measures were implemented to upgrade medical manpower. Salaries were increased, and the leadership of the medical and psychiatric community was enlisted to help encourage physi... | 488,935 | [
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Forum sparks creative energy. | Human support committee provides a forum where staff, patients, and administration can become involved in the planning, implementation, and evaluation of patient services. | 488,958 | [
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Needed: model law on the charitable corporation. | Nearly a dozen years ago, the McGrath Thesis stimulated controversy about Catholic corporations as property owners. Though no court has ever ruled that a charitable corporation's control is vested in the general public, institutions should understand state and federal laws that affect both property ownership and its di... | 488,989 | [
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X-linked mental retardation with macro-orchidism and marker X chromosomes. | A family with X-linked mental retardation and a marker X chromosome was ascertained by the presence of macro-orchidism in the three institutionalized probands. Verbal evaluation revealed a generalized language disability with commonly occurring articulation errors. The heterozygous females in this family exhibited some... | 489,008 | [
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Concordant congenital malformations in twins with inherited translocation: t(9p--;13q+). | Several members of a family with a translocation between the short arm of chromosome 9 and the long arm of chromosome 13(9p--;13q+) are presented. Although the translocation found in various members of the family looked alike and appeared to be balanced, the clinical features were different. The like-sex twins displaye... | 489,011 | [
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Sister chromatid exchange in peripheral lymphocytes of subjects vaccinated against measles. | The SCE frequency was studied in cultures of peripheral lymphocytes from three subjects before and after vaccination against measles. The immunological vaccination reactions were monitored by antibody titration and by measurement of DNA synthesis in peripheral lymphocytes. In two of the subjects, on the 14th day after ... | 489,014 | [
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Association between Duffy blood groups and serum level of the pregnancy zone protein. | In a previous study of psoriatic patients we found increased serum levels of the pregnancy zone protein (PZ) in individuals of blood groups O and Fy(a-). In this study we found an association between the PZ serum level and the Fy(a-) blood group also in young healthy males. Thus the association between the PZ serum lev... | 489,024 | [
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Thin-layer chromatographic method for estimation of gamma-aminobutyric acid from brain. | The present method describes the estimation of gamma-aminobutyric acid (GABA) from adult rat brain by thin layer chromatography (TLC). The major advantage of this TLC method is the sensitivity and repidity of estimation. About 93 to 98 percent recovery is possible by this procedure and this shows linearity up to 9 micr... | 489,090 | [
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Capacity of anaerobic bacteria from necrotic dental pulps to induce purulent infections. | Combinations of bacteria isolated from the root canals of teeth with necrotic pulps and periapical bone destruction were tested for their capacity to induce abscess formation and transmissible infections when inoculated subcutaneously into guinea pigs. Transmissible infections could be induced with combinations obtaine... | 489,126 | [
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Colored gift wrapping papers as a potential source of toxic metals. | Sanitary land fills are the alternate to waste incineration in New Jersey. While industrial waste disposal is controlled, few restrictions apply to the disposal of domestic solid waste. Among the materials of concern from domestic sources are colored gift wrapping papers. Cadmium, chromium, copper, iron, manganese, mol... | 489,218 | [
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The prevalence of diabetes mellitus in a rural community in Iraq. | A survey was undertaken to estimate the prevalence of diabetes mellitus in a rural community in Iraq. Blood-sugar estimations after glucose-loading were performed on a sample of a village population 15 + years. 4.8% had diabetes and a majority of them had symptoms referable to their diabetic state. Diabetes was totally... | 489,227 | [
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Empirical torsional potential functions from protein structure data. Phi- and psi-potentials for non-glycyl amino acid residues. | The torsional potential functions Vt(phi) and Vt(psi) around single bonds N--C alpha and C alpha--C, which can be used in conformational studies of oligopeptides, polypeptides and proteins, have been derived, using crystal structure data of 22 globular proteins, fitting the observed distribution in the (phi, psi)-plane... | 489,256 | [
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Serioangiographic study of renal cortical necrosis induced by administration of estrin and vasopressin in rats. | We report a serioangiographic method in rats which permits assessment of the course and dimensions of the renal arteries, the durations of the arterial and venous phases, and the intensity and uniformity of the renal parenchymal filling. The procedure was employed to study the mechanism by which administration of vasop... | 489,269 | [
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Cardiovascular effects induced by the injection of a new nonionic contrast medium (Iopamidol): experimental study in dogs. | The hemodynamic effects induced by the injection in the pulmonary artery of the new nonionic water soluble contrast medium Iopamidol were compared with those obtained by the injection of two other currently used contrast media (meglumine diatrizoate and sodium iothalamate). The experiments were carried out in nine mong... | 489,271 | [
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[Indications for surgery in adrenocortical disease]. | The surgical treatment of adrenocortical diseases indicated for hormone-secreting neoplasms and for definite cases of Cushing's disease. The surgical indication will be discussed. Since primary hyperaldosteronism caused by nodular hyperplasia of the adrenals needs a medical rather than a surgical treatment, a preoperat... | 489,396 | [
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[Medical support in surgery for pheochromocytoma]. | The occurrence of hypertensive crises, arrhythmias and hypotensive crises during surgery for pheochromocytoma can be prevented both preoperatively and intraoperatively by adequate alpha-adrenergic blockade and volume replacement. Only in a few cases is additional beta-adrenergic blockade necessary. Preoperatively the a... | 489,398 | [
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[Surveillance of 110 patients after ureterolithotomy]. | Between 1971 and 1975 we controlled 110 patients after ureterolithotomy. Early complications were one nephrectomy and two wound-infections. As late complications we saw one partial stenosis of the ureter. Our results show that ureterolithotomy is a low risk intervention. | 489,407 | [
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[Clinical considerations on posttraumatic osteitis]. | Posttraumatic bone infection very often signifies a life threatening complication. However, it must no longer be accepted that amputation of the afflicted limb be the logical treatment of such a complication. A surgeon who offers the advantages of operative treatment of a fracture to his patient must also be able to co... | 489,417 | [
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Two types of congenital hydrocephalus induced in rats by X-irradiation in utero: electron microscopic study on the telencephalic wall. | Stage-specific incidences of congenital hydrocephalus induced by X-irradiation of pregnant rats showed a bimodal distribution. At a dose level of 200 R, 100% hydrocephalic offspring were obtained by irradiation at embryonic days 11 and 14. When pregnant rats were subjected to 200 R X-irradiation at embryonic day 11, nu... | 489,463 | [
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Total fibre numbers in cross sections of the semitendinosus in athletic and non-athletic horses and dogs. | The numbers of fibres in the complete cross section of the semitendinosus were estimated in 58 equines and 59 canines of differing types. Animals selected for swiftness--thoroughbred horses and greyhounds--have a greater number of fibres in a cross section of their semitendinosus than other members of their species, wh... | 489,469 | [
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Anatomical closure of the ductus arteriosus: a study in 35 specimens. | The process of anatomical ductal obliteration appears to be gradual and to involve proliferation of intima and media (mainly the latter) producing mounds, mucoid-filled spaces and fragmentation of the internal elastic membrane. Dissociation of the inner media may also be involved. The persistent ductus can be recognize... | 489,470 | [
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Effects of self-instructional training on second- and third-grade hyperactive children: a failure to replicate. | Bornstein and Quevillon (1976) demonstrated generalization from a 2-hour self-instructional training session to on-task behavior in the classroom with 4-year-old overactive children. In an attempt to replicate this work with older children, eight 7- and 8-year-old hyperactive children were assigned to either a self-ins... | 489,479 | [
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Multiple-baseline analysis of a token economy for psychiatric inpatients. | Twelve behaviors selected for reinforcement among 16 chronic psychiatric inpatients were divided into four classes: (a) personal hygiene, (b) personal management, (c) ward work, and (d) social skills. A token economy program was introduced for each class in a sequential, cumulative, multiple-baseline format. Correction... | 489,481 | [
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Personal pronouns and the autistic child. | The long-recognized difficulties of the speaking autistic child with the use and nonuse of personal pronouns ["reversals" and "avoidance"] have been generally attributed either to the nondifferentiation of the self or to the frequently coexisting symptom of echolalia. These explanations are reconsidered in this eclecti... | 489,511 | [
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Childhood psychosis in the preschool child. | Six cases of childhood psychosis in children 3 to 5 years of age are summarized in order to alert clinicians to include this clinical entity in the differential diagnosis of children with major developmental difficulties. They represent children treated in a day, nonresidential treatment facility in a suburb of New Yor... | 489,513 | [
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Double-blind study of thioridazine and haloperidol in geriatric patients with a psychosis associated with organic brain syndrome. | Forty geriatric patients from the psychiatric ward of a state hospital were enrolled in a 12 week double-blind comparative study of the concentrate forms of thioridazine and haloperidol. The objective of the study was to assess the efficacy and safety of these drugs in the treatment of psychosis associated with organic... | 489,517 | [
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Case studies in neuropsychiaatry. II: Conversion pseudodementia. | A patient is described who experienced pseudodementia as a conversion reaction. The patient was considered to be demented originally because of the evidence for profound cognitive impairment elicited on mental state examination. Careful analysis of the patient's verbal production in unstructured situations and of her ... | 489,525 | [
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The significance of the serum levels of vitamin B-1 and magnesium in delirium tremens and alcoholism. | The relation between serum levels of vitamin B-1 and magnesium at admission, and the clinical state was studied in hospitalized patients with either alcoholism or delirium tremens. Vitamin B-1 was deficient in the delirium group, magnesium in both groups. There was no correlation between vitamin B-1 and magnesium level... | 489,530 | [
-0.2841246,
0.00512321,
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0.1135166,
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0.1749367,
0.2996992,
0.3439439,
-0.07272881,
... |
Effect of thyroid hormone on the turnover of rat liver pyruvate carboxylase and pyruvate dehydrogenase. | Immunochemical techniques have been utilized to study the effect of thyroid status on the content and rates of synthesis and degradation of pyruvate carboxylase and pyruvate dehydrogenase in rat liver. Liver from hyperthyroid rats had twice the pyruvate carboxylase activity of normal rats while thyroidectomized rats ha... | 489,548 | [
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0.1370329,
0.09177607,
0.2470497,
0.05634005,
0.489687,
-0.1149804... |
Measurement of phenylalanine hydroxylase turnover in cultured hepatoma cells. | A substantially new method has been developed to measure protein turnover. Its basis is the notion that in labeling experiments a secreted protein can be used to determine the specific radioactivity of the intracellular amino acid precursor pool. To measure protein turnover in the Reuber hepatoma H4 cell line, cultures... | 489,556 | [
-0.05204073,
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0.3119906,
-0.1383445,
0.4460198,
0.1561673,
0.4823265,
-0.05632621,... |
Enkephalin generating activity of rat brain endopeptidases. | An amphiphilic substrate was used as the basis of a specific assay for peptidases which generate the opioid peptide methionine enkephalin. The substrate [Homoarg-14C]Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Homoarg is prepared by guanidination of the lysine analogue (which is beta-lipotropin 61-69) with O-methyl-[14C]isourea an... | 489,604 | [
0.06638162,
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0.1429307,
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0.06584228,
0.3765683,
0.3135785,
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0.2958548,
0.3442234,
0.3179908,
0.3531973,
0.08523761,
-0.105211,
... |
Insulin and glucagon stimulation of amino acid transport in isolated rat hepatocytes. Synthesis of a high affinity component of transport. | Insulin and glucagon stimulate amino acid transport in freshly prepared suspensions of isolated rat hepatocytes. The kinetic properties of alpha-amino[1-14C]isobutyric acid (AIB) transport were investigated in isolated hepatocytes following stimulation by either hormone in vitro. In nonhormonally treated cells (i.e. ba... | 489,605 | [
-0.2376709,
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0.1209196,
0.2081424,
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0.2921489,
0.008697225,
0.04268266,
-0.07082877,
-0.2150145,
-0.120689,
0.07006323,
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0.02898242,
-0.2847947,
0.01722207,
0.269641,
0.09246007,
0.1239096,
... |
Rabbit tubular basement membrane. Isolation and analysis of polypeptides. | Renal tubules from rabbit kidneys were isolated from thin shavings of the kidney surface. Basement membrane was then prepared following sonication of the isolated tubules. To insure preservation of the integrity of the basement membrane polypeptides, the protease inhibitors, diisopropyl fluorophosphate, ethylenediamine... | 489,609 | [
-0.07925727,
0.1832019,
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0.02861956,
0.1812957,
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0.338807,
0.2339473,
0.2967066,
0.2139832,
0.03746861,
-0.0988964,
0.04714953,
-0.1028533,
-0.1636653,
0.3554087,
-0.3767335,
0.2281207,
-0.0004270362,
0.07367209,
0.1617547,
0.09394136,
-0.2253971,
... |
Pulmonary emboli followed total hip arthroplasty: incidence study. | We compared twenty-five total hip-arthroplasty patients with twenty-five patients who underwent other operations on the lower extremity, with regard to evidence of pulmonary embolism as determined preoperatively and postoperatively from lung perfusion scans, ventilation scans, and pulmonary angiography. Blood gases and... | 489,652 | [
-0.02874426,
0.1188549,
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-0.2084167,
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0.00359469,
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0.1350901,
0.4277649,
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0.3712059,
0.1639998,
-0.01283684,
0.1913737,
0.2977178,
-0.1413191,
... |
The three syndromes of iliac osteomyelitis in children. | Iliac osteomyelitis was diagnosed, in many cases after considerable delay, in twenty (2.3 per cent) of 867 children with hematogenous osteomyelitis. In ten patients coagulase-positive Staphylococcus aureus was identified. The symptoms and signs of iliac osteomyelitis depend on the direction of spread of the inflammatio... | 489,653 | [
-0.08038068,
0.2363628,
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-0.02835556,
0.1588142,
0.1670166,
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0.2072308,
-0.08927247,
0.04060652,
0.3493778,
0.1521816,
-0.114093,... |
Inhibition by aphidicolin of cell cycle progression and DNA replication in sea urchin embryos. | We have recently found that aphidicolin, a tetracyclic diterpene-tetraol produced by several fungi, blocks DNA synthesis of sea urchin embryos by interfering with the activity of DNA polyermase alpha. These cells fail to proliferate in the presence of aphidicolin. In continuation of these studies, we determined the dru... | 489,668 | [
-0.1743967,
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0.3433686,
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0.293009,
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0.0968096,
0.1926383,
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0.1122873,
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0.09859491,
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0.2309037,
0.3413957,
0.06401262,
-0.2662602,... |
Growth and G1 arrest of sarcoma virus trnasformed cells in serum free media. | Rous-sarcoma transformed BHK cells can be continuously cultured in a medium containing Eagle's Minimal Essential Medium, iron and biotin. The rate of cell multiplication increased when serine, or serine plus other non-essential amino-acids were added to the medium. With biotin deleted from the medium there is a reducti... | 489,675 | [
-0.3678007,
-0.377491,
-0.4067456,
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0.1035221,
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0.1509474,
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0.1322831,
0.1799359,
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0.366017,
-0.1958212,
0.3050681,
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0.1228284,
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-0.3024473,
-0.1431576,
0.3511732,
0.3904471,
-0.121498,
-0.232436,
0.01... |
A comparison of plasma protein changes induced by danazol, pregnancy, and estrogens. | Analysis of 25 plasma proteins was performed on blood drawn from 7 females before and during treatment with danazol. This steroid was found to induce a pattern of plasma protein changes similar to but not identical with that of other 17 alpha-alkylated anabolic steroids. For comparison, the same 25 plasma proteins were... | 489,712 | [
-0.005985001,
0.3263113,
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0.1409055,
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0.1136476,
0.2885169,
-0.1781448,
0.06805634,
-0.01672399,
0.06818137,
-0.5128083,
-0.08212043,
-0.3559346,
-0.07981288,
-0.238341,
0.4803315,
-0.1859487,
0.4145889,
-0.316992... |
Assimilation of protocatechuic acid and p-hydroxybenzoic acid as an aid to laboratory identification of Candida parapsilosis and other medically important yeasts. | Test for the ability of yeasts isolated from clinical specimens to utilize protocatechuic acid and p-hydroxybenzoic acid were carried out by using techniques that are commonly employed to test assimilation of carbon sources. A total of 60 isolates of Candida parapsilosis and 5 isolates of Candida humicola readily assim... | 489,723 | [
-0.08805668,
0.0239526,
0.4617698,
-0.1004348,
0.2839478,
-0.2003833,
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0.02265218,
-0.04253196,
-0.1487781,
0.4006212,
0.2714258,
-0.3494326,
-0.2108673,
-0.1150995,
-0.1195493,
-0.3963686,
0.4243683,
0.03853671,
-0.3718001,
0.3768691,
0.2268592,
-0.06834305,
... |
Self-concept and identified problem differences between pre- and postmenarcheal adolescents. | Examined differences in the number and types of problems as well as in self-reported self-concept between 232 middle and low SES pre- and postmenarcheal adolescents. The study also examined differences in these variables across four developmental levels of menarcheal status: Initial, Intermediate, Middle, and Establish... | 489,736 | [
-0.1154412,
0.3211676,
0.005642142,
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0.3247947,
-0.3695269,
-0.3102521,
-0.1192151,
-0.08715767,
-0.07345025,
0.2482751,
0.02382778,
-0.593683,
-0.4175896,
-0.9685361,
-0.07859777,
0.08157491,
0.3129826,
-0.2057337,
0.03697373,
0.1398647,
0.1888989,
0.03258729,... |
The relationship of sex role and levels of defensiveness to self-reports of fear and anxiety. | Examined the conclusions of previous research that found that femine Ss perceive themselves as experiencing greater fear and anxiety than Ss with a masculine sex-role orientation. The current study hypothesizes that these results may be confounded by the amount of expressive defensiveness exhibited by Ss (N = 99), inde... | 489,741 | [
-0.1791782,
0.02186376,
-0.1066808,
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0.07363235,
-0.3446599,
-0.14919,
-0.2982033,
-0.1370275,
-0.1454172,
0.06022727,
0.1506818,
-0.09724756,
-0.4590988,
-0.1649349,
-0.5224841,
-0.2183129,
0.09495015,
-0.08292477,
0.1062254,
0.1436688,
-0.132692,
-0.2126018,
... |
Clinical pharmacology of sodium cellulose phosphate. | The safety and effectiveness of sodium cellulose phosphate (SCP) in the treatment of calcium urolithiasis of absorptive hypercalciuria was explored. Eighteen patients with absorptive hypercalciuria with intestinal hyperabsorption of calcium, normal or suppressed parathyroid function, and active stone disease received 1... | 489,764 | [
-0.2713786,
-0.01531846,
-0.1237096,
-0.3617359,
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-0.22687,
-0.2072393,
0.04566044,
-0.1602741,
0.1037759,
0.07453837,
0.1225192,
-0.1841461,
0.1954606,
-0.7558377,
0.01821104,
-0.06148368,
-0.04493275,
-0.2911583,
0.2233655,
0.5478871,
0.2326049,
-0.1105303,
... |
An analgesic comparison study of indoprofen versus aspirin and placebo in surgical pain. | Single oral doses of 100 and 200 mg indoprofen were compared with 600 mg aspirin and placebo in a double-blind, completely randomized study of hospitalized patients with postoperative, post-fracture, or musculoskeletal pain. The patients evaluated their pain for 5 hours after administration of the study drug. Each of t... | 489,767 | [
-0.08899725,
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-0.0006229813,
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0.1246736,
0.2302637,
-0.375654,
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0.005097266,
-0.04824647,
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-0.3227855,
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0.1605683,
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0.2141591,
-0.08597407,
0.0001937636,
-0... |
Spinal projections from the mesencephalic and pontine reticular formation in the North American Opossum: a study using axonal transport techniques. | The results from several experimental approaches lead to the following conclusions. The nucleus cuneiformis projects to at least lumbar levels of the spinal cord. Its axons course through the ipsilateral sulcomarginal and ventral funiculi to distribute within lamina VIII and adjacent portions of lamina VII. Neurons wit... | 489,785 | [
0.0841986,
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0.1552224,
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0.272686,
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0.03431781,
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0.04898155,
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0.350227,
0.2114769,
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0.1262271,
0.06892011,
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0.05594245,
0.3147748,
-0.04473575,
0... |
Topological analysis of the brain stem of the crossopterygian fish Latimeria chalumnae. | The ventricular sulcal pattern and the cellular structure of the brain stem of the single surviving crossopterygian species Latimeria chalumnae have been studied in transversely cut Nissl, Klüver-Barrera and Bodian stained serial sections. Five longitudinal sulci, the sulcus medianus inferior, the sulcus medianus super... | 489,795 | [
0.2015091,
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0.2127468,
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0.2656498,
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0.3290977,
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0.252266,
0.08585777,
0.04564353,
0.0809425,
... |
Narrow-band AP latencies in normal and recruiting human ears. | Derived narrow-band action potential latencies increase monotonically with decreasing central frequency, and can be interpreted as reflecting the traveling wave delay in the cochlea. It was found that, for recruiting human ears with average flat hearing losses around 40 dB, this accumulating latency increase was smalle... | 489,815 | [
0.03912549,
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0.3820706,
0.05694583,
0.05471557,
... |
Automatic speech recognition using psychoacoustic models. | An approach to automatic speech recognition is described, which, in a straightforward way, follows the concept of (1) preprocessing in terms of auditory parameters and (2) subsequent classification and recognition. The preprocessing system has been realized in analog hardware, while recognition is carried out on a digi... | 489,818 | [
-0.1663768,
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0.07397317,
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0.1002969,
0.1014097,
-0.4133202,
0.4967619,
-0.009481573,
-0.223928... |
Gender-deviant boys compared with normal and clinical control boys. | The physical movement and social characteristics of effeminate behavior-problem, referred boys (N = 13) were compared with those of normal boys (N = 25) and boys (N = 12) referred for nongender problems. Parent reports, observer ratings, and videotapes were collected in a series of structured tasks. As expected, mother... | 489,847 | [
-0.3516277,
0.7317266,
-0.3409311,
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0.1285715,
0.0126933,
-0.1251477,
... |
[Lymphangiomatous hyperplasia with eosinophilia; Kimura's disease (author's transl)]. | Kimura's disease is a benign affection of young people in which there are non-specific subcutaneous nodules, mainly found in the region of the head. They can be identified by their particular histological appearance which includes vascular and inflammatory components, and by local and sometimes blood eosinophilia. The ... | 489,888 | [
-0.2205033,
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0.3971848,
0.2206667,
0.01135933,
0.09624699,
0.1734694,
-0.104008... |
[Conjunctival biopsies in diffuse amyloid (author's transl)]. | Amyloid well known as a homogeneous eosinophilic material deposited in various body tissues. Conjunctival biopsies in four patients distributed among the different classical type of diffuse amyloidosis demonstrate the diagnostic value of this simple procedure. In all cases, by optic microscopy amyloid deposits were see... | 489,893 | [
-0.1202544,
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0.07592903,
0.1795516,
0.2846589,
0.1736454,
0.03383277,
... |
[For or contra Crédé's method? (author's transl)]. | We no longer see newborn gonococcal endophtalmia. In France, it was the direct consequence of practical obligations. As gonococcic infection is growing up all over the world, is it wise to give up every prophylactic procedure? That is the question. | 489,897 | [
0.0589039,
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0.5923201,
0.08095172,
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0.... |
[Venous pressure in the expulsive hemorrhages and loss of the vitreous (author's transl)]. | It is insisted in the importance of the rising venous pressure as a cause of concause of the loss of the vitreous and the expulsive hemorrhages. We remind a simple way of measuring the venous pressure clinically and we recommend the inclined position of the patient as a prophylactic way to avoid the venous hyperpressur... | 489,902 | [
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0.1358114,
0.178521,
0.08147871,
0.2590362,
0.01881998,
-0.15883... |
Effects of estrogen on the release of gonadotropins and prolactin in male pseudohermaphrodites. | Three adult patients with male pseudohermaphroditism were given 15 microgram/kg body weight of 17 beta-estradiol im daily (at 08:00 hours) for 12-15 days and circulating levels of gonadotropins, prolactin and estradiol were determined by radioimmunoassay before and during the steriod course. All patients had elevated g... | 489,915 | [
-0.4949134,
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0.1027003,
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0.1646112,
0.3719591,
0.1844959,
0.08582319,
... |
Distribution of sexes in cattle. | Data were obtained from records of 1,046 Holstein dams included in the dairy herd at Cornell University during the years 1940 through 1977. Sex by order of parity was determined for the offspring of each dam. The overall sex ratio for 4,245 single parities was 52.74 percent males. Sex ratios for different parities were... | 489,956 | [
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0.111426,
0.1888939,
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-0.07666336,
0.1441169,
-0.02692991,... |
Linkage group IV in the Syrian hamster: spontaneous seizure and jute. | It was shown that sz and J are closely linked and that the recombination frequency between these two genes is 7.41 +/- 2.91. It was also shown that J is not linked with markers in linkage groups I and III, and that sz is not linked with a marker in linkage group II. Therefore, linkage between sz and J is a new linkage ... | 489,957 | [
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-0.2290883,
0.09635314,
0.02610667,
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... |
Solid-phase radioimmunoassay techniques for the detection of African swine fever antigen and antibody. | A solid phase radioimmunoassay (RIA) has been successfully developed to measure both African swine fever virus (ASFV) antigen and antibody. Studies show that the assay is reproducible and will detect limiting antigen concentrations equivalent to 50--500 HAD50/ml. Both direct and indirect antibody RIA have been develope... | 489,964 | [
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... |
In vitro killing of S. mansoni schistosomula by eosinophils from infected rats: role of cytophilic antibodies. | The cytotoxic effect of peritoneal cells from Schistosoma mansoni-infected rats against antibody-opsonized or nonopsonized schistosomula in vitro has been studied during the course of infection. Eosinophil-enriched cell preparations were shown to have a high cytotoxic effect on schistosomula in the absence of antibody.... | 489,980 | [
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0.1303769,
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0.154624,
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Isolation of the fourth component (C4) of rat complement. | The fourth component of rat complement was purified to homogeneity by sequential chromatography of rat plasma in benzamidine on QAE-A50, SP-C50, hydroxyapatite, and gel filtration on Bio-Gel A 1.5. The final material was homogeneous on SDS-PAGE analysis and had a calculated m.w. of 198,000. A monospecific antibody agai... | 489,981 | [
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0.013... |
Macrophages/monocytes require cell-to-cell contact in order to regulate the growth of a murine lymphoma cell line. | The mechanism of the macrophage-regulated proliferation of the murine lymphoma cell line FIO 30 has been further investigated. It appears that the macrophage is alone in its ability to support FIO 30 growth; a macrophage-like cell line, however, is unable to provide the stimulus required by the FIO 30 cells for their p... | 489,982 | [
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Enzyme-linked immunosorbent microassay for quantification of specific antibodies to collagen type I, II, III. | An enzyme-liked immunosorbent assay (ELISA) is described for determination of antibodies to collagen type I, II, III in serum or other body fluids. Polystyrene microplates are coated with either collagen I, II or III, and samples of body fluids being tested are incubated in the plates. Antibodies which attach specifica... | 489,989 | [
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Quantitation of immune complexes by nephelometry. | Laser nephelometry was used to quantitate immune complexes and IgG aggregates in native sera. Sensitivity limits and calibration curves were in good agreement with the C1q binding assay frequently used for measuring immune complexes. Distinction between sera containing lipids or immune complexes was achieved by polyeth... | 489,992 | [
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The ceruminous glands in chronic suppurative otitis media. A histological and histochemical study. | The ceruminous glands have been studied histologically and histochemically in twenty patients suffering from chronic suppurative otitis media with discharging ears, and in ten patients with dry central perforations, in comparison with normal ears. The present study revealed hyperactivity of the glands initially; later ... | 490,031 | [
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Malignant tumours of the nasal septum. | (1) Primary malignant tumours of the nasal septum are rare. (2) Forty-three cases of primary malignant septal tumours are presented and analyzed. (3) This present series is compared with the 97 previously reported cases. (4) The commonest primary malignant tumour at this site is squamous cell carcinoma. (5) The aid of ... | 490,033 | [
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A convenient synthesis of phosphatidylcholines: acylation of sn-glycero-3-phosphocholine with fatty acid anhydride and 4-pyrrolidinopyridine. | A high-yield synthesis of saturated, unsaturated, and short chain phosphatidylcholines from sn-glycero-3-phosphocholine is described. The procedure offers advantages over other reported procedures for the synthesis of phosphatidylcholine in that the large-scale synthesis and purification can be achieved in a minimum ti... | 490,045 | [
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Lipid structure and the behavior of cholesteryl esters in monolayer and bulk phases. | The behavior of cholesteryl esters at the air-buffer interface was studied as a function of molecular area and the presence of noncholesterol-containing lipids (colipids). The data obtained indicate that cholesteryl esters with other than long, saturated acyl groups can be present in surface phases up to packing densit... | 490,053 | [
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... |
Self-reported morbidity data as an indicator of regional resource requirement. | In this paper five variables are taken from the General Household Survey and the statistical technique of multidimensional scaling is used to estimate the relationships between the standard economic regions of England and Wales in terms of their self-reported morbidity. An estimate is then made of the proportion of res... | 490,093 | [
-0.007784589,
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0.1392827,... |
The impact of training traditional birth attendants on the utilisation of maternal health services. | The impact of training traditional birth attendants (TBAs) on the utilisation of maternal health services at a rural health training centre in India has been studied. Records of the utilisation of the services for two periods of six months each (one before training and one after) have been analysed. A marked improvemen... | 490,094 | [
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Light-induced acceleration of retina development in a mouth-brooding teleost. | Rearing animals in the dark had been shown to be either without effect on the development of the retina or to result in a reduction or a delay of retinal maturation. In the present study, the influence of light on a retina which normally develops under conditions of very dim light has been investigated. When 3-day-old ... | 490,119 | [
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Specificity of inhibition by steroids of porcine oocyte maturation in vitro. | In order to examine the influence of several steroids on the process of oocyte maturation, denuded (adherent cumulus granulosa cells mechanically removed) and intact (cumulus granulosa cells left attached) porcine oocytes were cultured in the presence or absence of estradiol-17 beta, estradiol-17 alpha, testosterone, c... | 490,131 | [
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0.2320078,
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Ultrastructure of Aplysia neurons having different degrees of light sensitivity. | The relationship between ultrastructure and photosensitivity of pigmented neurons of the abdominal ganglion of Aplysia californica was investigated using electron microscopy and electrophysiological methods. Four identified neurons of similar light microscopic appearance were examined; two are photoresponsive and two a... | 490,156 | [
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Lobster claw motorneurons respond to contralateral sensory stimuli. | Unilateral sensory stimuli in an isolated lobster claw--ganglion preparation elicits soma and axon spikes in homologous motorneurons in the ipsilateral as well as the contralateral hemiganglion. This cross excitation of the motorneurons provides a basis for bilateral reflexes in the claw and is likely mediated through ... | 490,157 | [
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Conditioning of the H reflex by stimulation of the posterior tibial nerve in Parkinson's disease. | The excitability curve of the H reflex conditioned by stimulation of a mixed nerve was studied in eight Parkinsonism patients, before and after L-dopa therapy. There was no significant variation between the two curves. However, there was a reduction of the normal early inhibition of the H reflex conditioned by exteroce... | 490,175 | [
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Interictal acute psychoses in temporal lobe epilepsy during withdrawal of anticonvulsant therapy. | Acute interictal psychotic attacks during withdrawal of medication are described in two patients with temporal lobe epilepsy submitted to depth EEG study with a view to surgical treatment. The patients were on chronic treatment with clonazepam associated in one with phenobarbitone and in the other with phenobarbitone p... | 490,178 | [
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Concept of neuron types in gustation in the rat. | 1. In taste neurophysiology, from Pfaffmann's (49, 50) pioneering work until the present, the possibility of types of neurons corresponding in some sense with the "primary" taste qualities of Henning (33) has been entertained: recently types of gustatory neurons in peripheral nerves have been established according to w... | 490,200 | [
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Hepatic-portal glucose and insulin levels: relationship to glucose-induced satiety and hunger. | The hepatic-portal infusions of both smaller and larger glucose loads, which had no significant effect on food intake in chronic feeding experiments, produced only a brief dose-dependent peak-like elevation in glucose and insulin levels. In contrast, metabolic changes produced by duodenal infusions were greater and con... | 490,204 | [
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Influence of dietary zinc on lead toxicity during gestation and lactation in the female rat. | Confirmed pregnant female albino rats received a purified diet containing either 12 or 120 ppm zinc with or without lead (0 to 500 ppm) from day 0 gestation through day 16 of lactation. An 11% reduction in dam weight gain during gestation and a 12% reduction in average pup weight in rats fed the low zinc plus lead diet... | 490,208 | [
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Mortality among workers employed in the pharmaceutical industry: a preliminary investigation. | The cause-specific mortality experience of 826 plant employees and 249 sales representatives employed by a large U.S. pharmaceutical firm was examined to determine if there were unusual patterns of fatal disease that might relate to factors in the work environment. Deaths that occurred between 1954 and 1976 among activ... | 490,223 | [
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Fluoride concentrations in urine of delivery ward personnel following exposure to low concentrations of methoxyflurane. | Midwives and other delivery ward personnel exposed to methoxyflurane do not have measurable traces of the agent in expired air when examined soon after exposure. This may imply a rapid uptake of the anesthetic. If this is the case, then the products of the metabolism of methoxyflurane, such as fluoride, may appear in t... | 490,224 | [
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Is a healthier person less susceptible to noise-induced hearing loss? | Several studies in the literature suggest that poor health is related to hearing loss. One hundred subjects claiming occupational hearing loss were chosen randomly for this study. Information was obtained on employment, noise exposure, medical history, family history, and use of cigarettes, alcohol, and medication. Phy... | 490,225 | [
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The nutritional therapy of histidinemia. | Control of the plasma histidine level in histidinemia is possible with the use of an amino acid mixture free of histidine and a carefully monitored intake of histidine. This regimen is compatible with good physical growth and normal mental development. If further clinical experience demonstrates that widespread nutriti... | 490,237 | [
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Who pays the bill for neonatal intensive care? | The Children's Hospital Newborn Emergency Service conducted 174 transports to the Newborn Center during a four-month period in 1976. The transport charge directly related to the distance between the referring hospital and the NBC. Two years after the NBC discharged the last study infant, 150 of 174 accounts have been p... | 490,247 | [
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Hemithyroid agenesis associated with a cervical thymic cyst. | A case is presented of a 7-yr-old boy with left hemithyroid agenesis associated with cervical thymic cyst. No left parathyroid glands were found. The diagnosis was established after surgical excision and histologic examination. Clinical and embryological implications of this condition are briefly discussed. No similar ... | 490,296 | [
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Pseudomonas septicemia; necrotizing bowel lesions (NEC) and skin lesions in a 5-mo-old child. | Necrotizing enterocolitis (NEC) that occurs in the high risk neonate is not usually associated with pathogenic organism. In older children the presence of NEC is often due to infection with a specific pathogen. A case of a five month old child with pseudomonas aeruginosa septicemia presented with typical NEC. in the co... | 490,302 | [
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0.1723296,
0.3147564,
-0.05428064,
... |
Focus of attention, chronic expectancy, and responses to a feared stimulus. | An attentional model of fear-based behavior is proposed and a study that tested the model is reported. It was predicted that among subjects with moderate fear of snakes, heightened self-attention during an approach attempt would cause increased awareness of existing anxiety, followed by one of two courses of events: Su... | 490,310 | [
-0.187307,
0.09354068,
-0.511323,
0.1803284,
0.3474603,
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0.4108873,
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0.3091432,
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0.2111972,
0.2934321,
0.1413459,
-0.05004846,
0.075... |
Studies on the N-demethylation and O-de-ethylation of ethylmorphine[6-3H] by male rat hepatic microsomes. | A sensitive and convenient radioassay for the in vitro determination of ethylmorphine N-demethylase and O-de-ethylase activity has been developed. Ethylmorphine[6-3H] was prepared by reduction of the corresponding morphinone in nearly quantitative yield. After incubation with hepatic microsomes from male rats, the reac... | 490,320 | [
-0.1540542,
0.1044078,
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0.0173185,
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0.1697418,
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0.240084,
0.2086796,
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0.211058,
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0.3585423,
0.5304881,
0.3805715,
0.1345214,
-0.01948023,
-0.144231,
0.1145... |
Procaine as an acetylcholine agonist in snail neuron. | Low concentrations of procaine (10(-5) M) are capable of provoking changes in the membrane potential of snail neurons. This effect is produced by direct application to the membrane and is characterized by a short response time and rapid reversibility. The resulting potential change has the same properties as that which... | 490,329 | [
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0.2562066,
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0.2340265,
0.2868085,
0.04637989,
0.09689836,
0.... |
Propagation of electrical spiking activity along the small intestine: intrinsic versus extrinsic neural influences. | 1. The electrical activity of the small intestine of conscious dog, recorded by means of chronically implanted electrodes, was related to the transit time estimated by phenol red infusion and its propagation observed after a single or double transection and following either isolation or removal of a 50 cm jejunal loop.... | 490,338 | [
0.02177549,
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0.07723243,
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0.01712367,
0.02373004,
-0.01144939,
0.04679276,
0.1003908,
0.1587... |
A comparison between the discharges of human nociceptive nerve fibres and the subject's ratings of his sensations. | 1. Impulses in cutaneous nerve fibres were recorded percutaneously with tungsten micro-electrodes from the superficial radial nerve of adult human subjects. 2. Eight units studied had conduction velocities below 1.5 m/sec, and thus belong to the class of C fibres. On the basis of their responsiveness to mechanical and ... | 490,345 | [
0.3394334,
0.0700352,
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0.2057095,
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0.0453079,
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0.2161434,
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-0.197251,
-0.176201,
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0.2756701,
0.3150314,
0.1715533,
0.1052978,
0.2882... |
Responses in the diagonal band of Broca evoked by stimulation of the fornix in the cat. | 1. Field potentials were recorded within the boundaries of the septal component of the diagonal band of Broca following stimulation of the fornix. The position of the recording electrode was marked by pressure injection of Alcian blue dye. 2. Stimulation of the medial aspect of the ipsilateral fornix produced a simple ... | 490,352 | [
0.008500744,
0.3141087,
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0.1813904,
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-0.09358475,
0.1242471,
-0.3095988,
0.03888108,
0.09342784,
0.2774827,
0.1145145,
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0.2452556,
0.1538979,
-0.1117738,
0.1422133,
0.06571089,
0.1390095,
0... |
Influence of potassium, sodium, perfusion pressure, and isoprenaline on renin release induced by acute calcium deprivation. | 1. These studies were conducted in isolated perfused rat kidneys to determine the influence of perfusion pressure, isoprenaline, K, and Na on renin release stimulated by acute Ca deprivation.2. Removing Ca from the perfusion medium for 10 min stimulated renin release and reintroducing Ca returned it toward control valu... | 490,364 | [
-0.3683957,
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0.1899458,
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0.1287692,
0.112203,
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0.02456423,
0.1105172,
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0.07741943,
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-0.3117371,
0.1162076,
-0.06740715,
0.07620814,
0.1678281,
0.06008464,
0.1560673,
... |
Subject instruction and long latency reflex responses to muscle stretch. | 1. Surface electromyographic recordings were made in eight normal subjects from the isometrically contracting elbow flexors before and during forcible extension of the elbow through 7 degrees in 50-150 msec. 2. Weh the subjects were instructed prior (2-5 sec) to a forthcoming stretch to 'resist' or to 'let go', they co... | 490,387 | [
0.04910861,
0.182243,
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-0.01811455,
-0.2189506,
-0.08937844,
-0.1020436,
0.3788666,
-0.1493309,
-0.3254958,
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-0.7346621,
0.2388517,
-0.3730721,
0.1489357,
0.406087,
0.146043,
0.1217038,
... |
[Osteo-onychodysostosis. One more report about a family case (author's transl)]. | A 9 year-old boy takes medical advice because of underdevelopment and intellectual insufficiency. The diagnosis of osteo-onychodysostosis (nail-patella syndrome) clinically expected is confirmed by X-ray examination. The main radiological signs of this disease are reminded of. You can also find a few remarks about fami... | 490,463 | [
-0.005034383,
0.007717042,
0.4968672,
0.03302729,
-0.03278291,
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-0.4839875,
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-0.1577666,
-0.008093334,
0.2167094,
0.3856899,
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0.1394142,
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-0.358505,
0.1414531,
-0.123501,
0.1640358,
0.3542741,
0.01832921,
-0.0438985... |
[Diagnostic value of arteriography in a case of splenomegaly of unknown origin (author's transl)]. | A 32 year-old patient was found to have a tender enlarged spleen with hardly any other signs apart from transient fever and moderate hepatomegaly. Coeliac arteriography was performed to eliminate the possibility of a splenic tumor. The splenic arteriography showed the presence of a great number of lacuna dispersed thro... | 490,479 | [
0.1362155,
-0.2466129,
-0.1234381,
0.06575075,
0.1714397,
-0.2195912,
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-0.1215347,
0.02068872,
-0.03275861,
0.1503759,
0.05838897,
0.1104174,
-0.2486256,
-0.5147396,
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-0.5057338,
-0.1212241,
0.2166314,
0.2611667,
0.2358293,
0.01186423,
-0.1468873,
... |
Cytotoxic activity of cerebrospinal fluids (CSF's) against lymphocytes and phagocytes: comparison of normal and systemic lupus erythematosus CSF's. | Fifty cerebrospinal fluids (CSF), 24 normal, 26 from systemic lupus erythematosus (SLE) patients were tested for cytotoxic activity against human lymphocytes, granulocytes and monocytes. Normal and SLE CSF's frequently killed all 3 cell types. Lympho- and granulocytotoxins often reacted at both 4 degrees/24 degrees C, ... | 490,521 | [
-0.2400657,
0.04084507,
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0.06864053,
0.1825064,
-0.08278174,
-0.06723794,
-0.09267576,
-0.1299468,
0.2637382,
-0.1063635,
0.3696811,
0.1067081,
0.1545403,
-0.08658911,
-0.05649692,
-0.1788978,
0.02665676,
-0.0550818,
0.7054743,
-0.1119572,
-0.1116376,
-0.020750... |
Antimycotic imidazoles. part 4. Synthesis and antifungal activity of ketoconazole, a new potent orally active broad-spectrum antifungal agent. | The preparation and antifungal properties of cis-1-acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl-methyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine (I) are described. Ketoconazole has, at low oral doses, a high in vivi activity against vaginal candidosis in rats and against cutaneous candidosis in guinea pi... | 490,531 | [
-0.0606347,
-0.09104979,
-0.05081346,
-0.05582008,
0.2576041,
0.2030195,
-0.4245118,
0.06758447,
-0.01423527,
-0.3520549,
0.1872571,
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0.04931021,
0.2079795,
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-0.945971,
0.1482989,
0.01717886,
-0.1127441,
0.3693461,
0.4517096,
-0.0367847,
... |
Adamantylthiourea derivatives as antiviral agents. | A series of nine 3-substituted 1-adamantylthioureas was prepared and tested for antiviral activity against influenza A2/Asian/J305 virus in vivo and in vitro. Protective dose 50 values were calculated for three of the compounds. One of these compounds, 7, has antiviral activity which compares favorably with that of ama... | 490,532 | [
-0.4124499,
-0.08667698,
-0.3757735,
-0.267447,
0.09494577,
0.01505479,
-0.3834373,
0.08282194,
0.1308458,
-0.1821623,
-0.07301997,
-0.1025136,
0.3152326,
-0.04781685,
-0.5088245,
0.07586231,
-0.1459011,
0.2629462,
-0.05413549,
0.3707961,
0.1278385,
-0.04212305,
-0.144369... |
Synthesis of fused [1,2,6]thiadiazine 1,1-dioxides as potential transition-state analogue inhibitors of xanthine oxidase and guanase. | Ring closure of ethyl 3-aminopyrazole-4-carboxylate with sulfamoyl chloride gave 1,7-dihydropyrazolo[3,4-c][1,2,6]thiadiazine-4(3H)-one 2,2-dioxide. The corresponding 4-amino analogue of this new heterocyclic ring system was similarly prepared from 3-aminopyrazole-4-carbonitrile. Treatment of 4,5,6-triamino-2H-1,2,6-th... | 490,539 | [
-0.3089579,
0.3059582,
-0.3044522,
-0.01432132,
0.2291962,
0.1176106,
-0.2397836,
-0.1560165,
0.07035858,
-0.2004208,
0.001825335,
-0.003425865,
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-0.7097638,
0.1423121,
-0.0503699,
0.2833508,
0.1361004,
0.2470695,
-0.06933556,
... |
Synthesis of some carbon-3 substituted 1,4-benzodiazepin-2-ones and their central nervous system effects. | Starting from 3-hydroxy-1,4-benzodiazepin-2-ones 1--3, via 3-chloro derivatives 4--6, 13 new C(3)-substituted 1,4-benzodiazepin-2-ones were synthesized. Reaction of 4--6 with ethylene glycol yielded 3-(beta-hydroxyethyl) derivatives 7--9. Similar reaction with the isopropylidene derivative of glycerol afforded 10--12, ... | 490,555 | [
0.0249057,
0.08654246,
-0.2454179,
-0.08142606,
-0.02209996,
-0.3442343,
-0.3453476,
0.05157341,
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0.06836861,
0.364027,
0.4317754,
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0.4010242,
-0.08791968,
0.481703,
0.07031709,
0.09480119,
-0.012985... |
Nitrosoureidonucleosides. | 3-Deoxyl-1,2-O-isopropylidine-3-(3-methylureido)-alpha-D-ribofuranose (2) was converted to 1,2,5-tri-O-acetyl-3-deoxy-3-(3-acetyl-3-methylureido)-D-ribofuranose (4) and the corresponding glycosyl chloride (7). These sugars were converted to the 3-deoxy-3-(3-methylureido)-beta-D-ribofuranosyl derivatives of adenine (6c)... | 490,557 | [
-0.2819332,
0.2609838,
-0.3667439,
0.06208885,
0.2181284,
0.09744401,
-0.1554514,
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0.03402101,
0.1296312,
0.2092596,
0.2219409,
0.1238486,
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-0.5212457,
0.1160239,
-0.09307062,
0.1004415,
0.4879741,
0.1076018,
-0.09980654,
... |
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