title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Intrauterine diagnosis of renal anomalies by ultrasonography. | The diagnosis of renal disease was made antenatally in three patients by ultrasonographic examination. In two cases a multicystic kidney was detected in utero and removed shortly after delivery. In another case, a hydronephrotic kidney was detected in utero; repair was then performed early, before symptoms developed in... | 495,596 | [
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Demonstration of antigenemia in patients with invasive aspergillosis by solid phase (protein A-rich Staphylococcus aureus) radioimmunoassay. | A solid phase radioimmunoassay (RIA) was used to detect Aspergillus antigenemia in three patients, two with autopsy proved disseminated aspergillosis and one with a suspected infection. These RIA studies suggest that screening for antigenemia may be a specific and sensitive diagnostic test for disseminated aspergillosi... | 495,632 | [
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Assessing community attitudes toward mentally retarded persons. | Although many researchers have found evidence of discrimination toward retarded individuals in employment, education, and housing, attitude-survey researchers generally report acceptance of retarded people in the community (Gallup, 1976; Gottwald, 1967). To examine this discrepancy, we compared responses on a survey co... | 495,660 | [
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The role of anaerobic bacteria in postpartum endomyometritis. | To evaluate the role of anaerobic bacteria in postpartum endomyometritis, intravenous metronidazole was used as the sole initial therapy in 25 women with clinical signs of infection. This agent has not been shown to have activity against aerobic pathogens in soft tissue pelvic infections. A clinical cure was obtained i... | 495,683 | [
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Speckle motion in laser refraction. II. Experimental. | The validity of expressions for the position of the plane of stationarity, apparent speed of speckle movement, and estimated observer ametropia is examined for laser refraction, using a cylindrical drum. The agreement between theory and experiment is satisfactory. It appears unlikely, however, that methods of subjectiv... | 495,686 | [
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Complement fragments, alveolar macrophages, and alveolitis. | Mechanisms of neutrophil infiltration into the rabbit alveolus have been investigated. Complement activation in the circulation induced pulmonary vascular margination but not a significant level of alveolar infiltration. Instillation of C5 fragments into the airways, however, attracted neutrophils into the alveolar air... | 495,697 | [
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Psychiatric sequelae of surviving childhood cancer. | Increasing survival rates for children with cancer raise questions about the long-term psychosocial impact of the disease and its treatment. Psychiatric evaluations of 114 survivors of childhood malignancies suggest a high rate of adjustment problems, with 59% indicating at least mild psychiatric symptomology. Intervie... | 495,703 | [
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Effect of fasting on insulin removal by liver of perfused liver-pancreas. | Using in situ perfused rat liver-pancreas preparations, the hepatic clearance of biphasically released endogenous insulin was studied using livers of fed and fasted rats. Hepatic insulin extraction was determined by subtracting the mean endogenous insulin output found in the posthepatic vena cava effluent of liver panc... | 495,713 | [
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Glucose carriers at maternal and fetal sides of the trophoblast in guinea pig placenta. | Trophoblast uptake and unidirectional influx of 3H-labeled hexoses were measured relative to L-[14C]glucose (extracellular marker) using a single-circulation, paired-tracer dilution technique. Successive runs were performed in the fetal and maternal circulations of isolated dually perfused guinea pig placentas, obtaine... | 495,740 | [
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Hemodynamic and excretory response of the neonatal canine kidney to acute volume expansion. | It is generally recognized that developing animals retain sodium due to an enhanced reabsorption in distal tubule segements, even when the amount administered is in excess of their needs. This study was designed to test the relationship between this relative inability to dispose of a saline load and the functional char... | 495,755 | [
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Community support programs: program evaluation and public policy. | The plight of chronic psychiatric patients in the community has led to a major federal effort to resolve fragmented and disorganized care. The Community Support Programs (CSPs) recently funded by NIMH offer the promise of reducing these difficulties by creating comprehensive human service systems at the local and state... | 495,796 | [
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Self-disclosure in therapy: marriage of the therapist. | The author presents how his interest on the general subject of self-disclosures in therapy evolved. Literature on this subject is reviewed with particular attention to intercurrent events in the therapist's life that may affect ongoing psychotherapy. Six clinical vignettes of psychotherapy cases illustrate varying reac... | 495,835 | [
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Role of angiography in the diagnosis of pancreatic neoplasms. | The vascular architecture of the pancreas has been described, but few reports indicate preoperative accuracy. During the last 3 years, selective superior mesenteric and celiac angiography was performed in 471 patients. In 35 of these patients, additional selective angiography of the superior pancreaticoduodenal and inf... | 495,855 | [
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[Evaluation of brachial plexus block. Comparison between supraclavicular and interscalene approach (author's transl)]. | A scheme for evaluating brachial plexus block was developed, which is based on anatomical structures and which utilizes simple neurological examination techniques. It facilitates the localization of the tip of the cannula near the plexus, gives an idea of the spread of the local anesthetic in the region of the trunks a... | 495,925 | [
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Antacid pulmonary aspiration in the dog. | The amount of damage resulting from pulmonary aspiration of gastric contents is determined primarily by the acidity of the aspirate. Thus, it has been recommended that the pH of stomach contents of pregnant women be increased by the oral administration of antacids prior to anesthesia for delivery. This study was done t... | 496,051 | [
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Effects of morphine sulfate on dorsal-horn neuronal responses to graded noxious thermal stimulation in the decerebrate cat. | Effects of morphine sulfate upon activity of the neurons of dorsal-horn lamina V as evoked by graded noxious thermal stimuli applied on the receptive field were studied in spinal cord-transected, decerebrate cats utilizing an extracellular microelectrode recording technique. All single units studied (n = 30) responded ... | 496,055 | [
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[Morphometric evaluation of osteoclasts in non-decalcified bone sections. Its value in the diagnosis of hyperparathyroidism]. | The authors assessed the surface areas of osteocytic lacunae in non-decalcified bone sections using a histomorphometric method involving a device with an adaptable drawing on the microscope and a graduated sheet. In 7 cases of primary hyperparathyroidism proven surgically and in 8 cases of hyperparathyroidism secondary... | 496,082 | [
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[Foetal pulmonary maturity: estimation by the palmitic/stearic acids ratio and by the Clements' test in amniotic fluid (author's transl)]. | Two parameters have been used to estimate the foetal pulmonary maturity: Clements' test or bubble test and palmitic acid/stearic acid ration. The reliability and the limits of these tests have been studied in function of several pathological pregnancies and the gestations's age. A value greater than 5 for the P/S ratio... | 496,083 | [
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[Double malformation discovered during investigations for hypertension; single pelvic kidney and occipitovertebral joint malformation (author's transl)]. | A young Portuges eman with a spastic gait was found to have a kidney lying below the bladder. This was the only kidney present and its blood supply was derived from a renal artery which was also the only one present. This renal abnormality was associated with a major malformation of the occipitovertebral joint (occipit... | 496,139 | [
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Bullous retinal detachment associated with renal failure: case report. | A case of bilateral bullous retinal detachment in a patient with long-standing disseminated lupus erythematosus is presented. Although several authors have reported the presence of bullous retinal detachment in association with chronic renal disease, in no other case have the ocular findings preceded the onset of frank... | 496,185 | [
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Endophthalmitis in a pediatric population. | A study of 22 consecutive cases of suspected endophthalmitis in children disclosed that 68% (15/22) were male with a mean age of 7.4 years. In contrast to adult populations, 86% (19/22) followed trauma in this series. Cultures were performed in 18 cases yielding positive results in 8 cases. Anterior chamber paracentesi... | 496,186 | [
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Corneal retraction and intraocular lens implantation. | A corneal retractor has been developed which when used after intraocular lens insertion insures against endothelial intraocular lens touch during the maneuvers of clipping or suturing various intraocular lenses to or through the superior iris. | 496,190 | [
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Hearing and age: research challenges and the National Institute on Aging. | Just as the ear trumpet once symbolized the elderly, so do contemporary approaches to hearing loss in the aged reflect many of the major themes in geriatrics and gerontology today. This paper begins by describing the National Institute on Aging (NIA) with particular emphasis on activities relevant to hearing in the eld... | 496,199 | [
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Evaluation of dextran with local anaesthesia for short-stay inguinal herniorraphy. | A prospective randomised study of 40 patients undergoing unilateral inguinal herniorrhaphy under local anaesthesia was undertaken. Half the patients received the local anaesthetic (0.25% bupivacaine) mixed with dextran 40 solution. Subjective and objective assessments were made of the postoperative pain experienced in ... | 496,237 | [
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Genetic study of the Cuiva Indians of Venezuela. | Serum and red cell protein markers were investigated in Cuiva Indians. Our ethnologic studies indicate that the low degree of genetic variability in this population is probably due to genetic drift. | 496,385 | [
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An alternative model of recombination and interference. | A model of four-strand crossing-over is presented in which all non-randomness is attributed to the non-Poisson distribution of the number of exchanges. Nth order recombination fractions and the coefficient of coincidence are calculated in terms of the model. It is shown that coincidence may be greater or less than unit... | 496,395 | [
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[Comparative study of cephalexin and cephradine distribution in the body of rats]. | Distribution regularities of cephalexin and cephradine, 2 semisynthetic cephalospor in antibiotics for oral use were studied on rats. It was found that the cephalosporins had a capacity for satisfactory penetration through the histochematological barriers. The drugs were rather rapidly absorbed from the gastrointestina... | 496,419 | [
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Acute gouty bursitis: report of 15 cases. | Fifteen cases of acute gouty bursitis were seen among 136 crystal-proved cases of gout. Bursal aspirate yielded yellow or pink fluid in 10, chalky white fluid in 1, and a small amount of bloody fluid in 4. Monosodium urate crystals were present in all. Bursal fluid leucocyte counts averaged 2.9 X 10(9)/1 compared with ... | 496,446 | [
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An examination of the dietary constituents of the cattle-biting louse, Bovicola bovis. | Starved Bovicola bovis were confined until they died, with dried cow blood, dried cow serum, primary hair, secondary hair and calf skin scales stained with 1% toluidine blue. Feeding occurred readily on skin scales, as shown by dark staining of the intestine, and minimally on primary and secondary hair; lice confined w... | 496,470 | [
0.03782795,
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0.207385,
0.04706582,
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0.08220771,
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0.1196847,
0.07213688,
0.2424086,
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0.13... |
Effect of Freund's complete adjuvant on the immune response of vasectomized rats. | Rats were vasectomized, vasectomized and injected in the epididymis with Freund's complete adjuvant (FCA), or only injected with FCA without vasectomy. All were positive for sperm agglutinins, in contrast to sham-operated or untreated controls. Generally, the highest titers were found in vasectomized or unoperated anim... | 496,510 | [
0.2974709,
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0.2013896,
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-0.01565877,
-0.2046736,
... |
Effect of 2,6-cis-diphenylhexamethylcyclotetrasiloxane on the reproductive organs of male mice. | Mice treated with tetrasiloxane, 20 and 40 mg/kg/day, showed lesions in the reproductive organs, cytological changes in the pituitary glands, and changes in levels of cholesterol, phosphomonoesterases, transaminases, 5'-nucleotidase, lactic and isocitric dehydrogenases, and ATPase. | 496,515 | [
-0.2095425,
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0.2953464,
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0.1301385,
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0.003497511,
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0.1992025,
0.1464788,
0.342139,
-0... |
[The relative contribution of the upper and lower segments to growth in boys]. | In a longitudinal growth study of 64 boys, the contribution of the upper and lower segments was analysed. The results are compared to an earlier study in girls, and the difference between the sexes was related to the puberty growth spurt. This is later, more prolonged and of greater amplitude in the boys. Lower segment... | 496,529 | [
0.08677052,
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0.1505158,
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0.2446718,
0.6334132,
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-0.1... |
[Visual behavior of the premature infant]. | Ocular reflexes were studied at birth in neonates of varying gestational ages and then followed every two weeks. It is possible to distinguish reflexes that may be present at birth that are dependent on gestational age and those acquired later. Each reflex corresponds to the establishment of neuronal corrections and th... | 496,538 | [
0.1278778,
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0.1692987,
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0.07480474,
0.07288932,
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Diffuse abnormal electromyographic insertional activity: a preliminary report. | The authors observed 10 patients referred for electromyographic examination in whom EMG findings were normal except for the presence of provoked positive sharp waves in essentially every muscle tested. The positive sharp waves were present only following needle electrode insertion. No fibrillation or fasciculation pote... | 496,609 | [
-0.1346579,
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0.05248949,
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0.4304834,
0.164257,
0.01731568,... |
Visual reaction time as a function of locus, area, and complexity of stimulus. | Reaction time (RT) of normal subjects to square-wave gratings of two different frequencies were related to locus of presentation, area, and stimulus complexity. Each frequency was presented to either side of the horizontal meridian (half size stimulus) or both sides stimultaneously (full size stimulus). The two differe... | 496,617 | [
-0.004721409,
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0.3208239,
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0.2649392,
0.1045999,
0.1558425,
0.5401435,
0.2939469,
-0.1485964,
... |
Cerebral atrophy in Parkinson's disease--represented in CT. | To clarify the importance of brain atrophy in relation to the symptoms of Parkinson's disease, 173 patients were examined by computed tomography (CT). In 51.4% of the CT findings, brain atrophy was considered to be pathological. Statistically significant relations of age and sex were found with regard to the extent and... | 496,619 | [
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0.03984527,
0.1843271,
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0.3061622,
0.08534454,
-0.01417039,
-0.0284289,
0.2805587,
-0.15564... |
Influenza virus infection of a newborn rats: virulence of recombinant strains prepared from a cold-adapted, attenuated parent. | Infant rats were infected with one of a series of influenza A viruses. The growth of viruses in the turbinates or lungs, and the ability of virus infection to potentiate a subsequent bacterial infection by Haemophilus influenzae (HIb), were measured. The three virus strains known to be virulent for man grew to relative... | 496,643 | [
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0.3570151,
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0.02456166,
0.1943819,
0.2556419,
0.06445314,
-0.07761058,
-... |
[Sequence of RNA and protein synthesis in wound fibroblasts]. | RNA and protein synthesis was studied in the mouse granulation tissue fibroblasts on the 3d and 7th days after wound production. An electron-radioautographic modification of the double marker method, based on the supposition that the two biosynthetic processes investigated occur, mainly, in different parts of the cell,... | 496,672 | [
-0.03450713,
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0.058703,
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0.1029205,
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0.5183288,
0.3032451,
-0.04298238,
-0.2628784... |
[Case of Nelson syndrome]. | A clinical description of Nelson syndrome developing in a woman of 44 is presented. Histologically the tumour of the hypophysis was an adenoma of mixed structure, electron microscopically it was found to consist of corticotropocytes in various stages of the secretory cycle. Adenoma of the hypophysis was diagnosed 4 yea... | 496,687 | [
-0.1031773,
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0.0191338,
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0.008776242,
0.4355115,
0.08099456,
0.004457824,
... |
Cerebrovascular disease. | Cerebrovascular disorders producing transient or permanent symptoms and signs are very common, but they are not the only causes of a sudden neurologic deficit. Careful examination of the cardiovascular system may indicate the likely cause of the lesion, while accurate neurologic localization is also useful in establish... | 496,728 | [
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0.305221,
0.3073407,
0.1365754,
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0.2835029,
-0.07830607... |
An evaluation of biomicroscopy of the conjunctival vessels. | Human clinical biomicroscopy is an aid to the assessment of the microcirculation in health and disease. It has only limited diagnostic value but in some important conditions gives helpful clues and in a few conditions pathognomonic information. Features which can be evaluated include intravascular red cell aggregation,... | 496,855 | [
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0.0807921,
0.3298173,
0.05812879,
0.08084187,
-... |
Genetics of the mammalian phenylalanine hydroxylase system. Studies of human liver phenylalanine hydroxylase subunit structure and of mutations in phenylketonuria. | Phenylalanine hydroxylase was purified from crude extracts of human livers which show enzyme activity by usine two different methods: (a) affinity chromatography and (b) immunoprecipitation with an antiserum against highly purified monkey liver phenylalanine hydroxylase. Purified human liver phenylalanine hydroxylase h... | 496,890 | [
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0.3832908,
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0.1468786,
0.1462197,
0.1863938,
-0.2220793,
-... |
The effect of inhibitors on the oxygen kinetics of terminal oxidases of Acanthamoeba castellanii. | 1. Respiration of growing cultures of Acanthamoeba castellanii is inhibited less than 60% by azide (35 mM); the respiration of early-exponential-phase cultures differs from that of late-exponential-phase cultures in being stimulated by up to 120% by low concentrations (less than 1 mM) of this inhibitor. Azide (0.5 mM) ... | 496,900 | [
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0.07768279,
-0.1288251,
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0.04439792,
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0.2478931,
0.326411,
0.3592891,
0.103669,
0... |
Endocytosis of beta-N-acetylglucosaminidase from sections of mucolipidosis-II and-III fibroblasts by non-parenchymal rat liver cells. | beta-N-Acetylglucosaminidase isolated from the secretions of fibroblasts of mucolipidosis-II and -III patients is internalized by cultured non-parenchymal rat liver cells. The rate of endocytosis compared with that of beta-N-acetylglucosaminidase from control fibroblasts was 11 and 19% for the enzyme from mucolipidosis... | 496,912 | [
-0.1030059,
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0.03641778,
0.09471548,
0.2743608,
-0.23054... |
Haem transport to the liver by haemopexin. Receptor-mediated uptake with recycling of the protein. | Rat [(59)Fe]haem-(125)I-labelled haemopexin complexes (700pmol/rat) associate rapidly and exclusively with the liver after intravenous injection into anaesthetized rats. The two isotopes exhibit different patterns of accumulation. Liver (125)I-labelled haemopexin is maximum 10min after injection (20+/-4.9pmol/g of live... | 496,916 | [
-0.4532996,
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0.1232483,
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0.433661,
0.01183084... |
[Production of infarction model in dogs by several brain arteries occlusion. Part 1: Production of hemispheric non blood supply model (author's transl)]. | Experimental brain infarction in model animals should most ideally be constant in the site of occurrence, be of severity that is controllable by the occlusion time of blood flow and, moreover, be reproducible at a high rate to desired extent and severity. However, among infarction models elaborated in animals so far, o... | 497,053 | [
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0.1260467,
0.2086389,
0.02162046,
-0.05947466,
... |
Effect of maternal position on fetal heart rate during extradural analgesia. | Using continuous cardiotocography, the effect of maternal position on fetal heart rate (FHR) was studied during extradural analgesia (EA) with either 50 or 100 mg of etidocaine without adrenaline for labour and vaginal delivery. Of 70 healthy parturients, 39 were supine and 40 were in the lateral position. FHR was norm... | 497,074 | [
0.15702,
0.2912849,
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0.03475821,
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-0.3708034,
-0.1814801,
0.2976175,
0.06373904,
-... |
Cimetidine: effect on pancreatic and biliary function in man. | 1 Pancreatic and biliary function were studied in eight patients taking oral cimetidine (1.6 g/day for 6 weeks) for endoscopically confirmed active peptic ulcer disease. 2 Postprandial jejunal tryptic activity and bile acid concentration were unchanged during cimetidine given for 1 and 6 weeks. 3 Postprandial gallbladd... | 497,088 | [
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0.259951,
0.07085778,
0.08755711,
0.1162939,
0.02689967,
0.225486,
... |
Histopathological changes of the nasal mucosa in active and retired nickel workers. | Histological examinations were made on nasal biopsy specimens from the middle turbinate in 318 active and 15 retired nickel workers and in 57 controls, to study the prevalence of nasal carcinoma or possible precancerous mucosal changes in nickel-exposed individuals. The histopathological changes were evaluated accordin... | 497,107 | [
-0.1844599,
-0.06441924,
0.05969718,
-0.1133074,
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0.1719996,
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0.325457,
0.42193,
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0.05184966,
0.01436024,
0.4834968,
0.07509162,
-... |
Investigation of time-gap formulae on the CRE system using mouse tissue as a biological model. | The cumulative radiation effect (CRE) is one of several empirical scalar descriptions of biological effect which enable corrections to be made for gaps in radiotherapy treatment. Predictions of this theory were tested using mouse crypt regeneration and mouse skin as biological models. These experimental results are dis... | 497,112 | [
-0.01829132,
-0.5673282,
-0.5483602,
0.08110224,
0.3329057,
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0.1464778,
0.00426019,
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0.1264765,
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0.3370091,
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0.1806168,
0.5348313,
0.1787622,
0.141748,
... |
Serum gonadotrophins, prolactin and ovarian steroids in primary dysmenorrhoea. | Serum samples were collected from 27 women with incapacitating primary dysmenorrhoea and from 16 normal women in the early part of the cycle (between day 3 to 6), at midcycle (between days 13 to 16) and in the late part of the cycle (between days 23 to 26) for determination of FSH, LH, prolactin (PRL), 17 beta-oestradi... | 497,135 | [
-0.2053606,
0.1074715,
0.1353798,
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0.0008043314,
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-0.01401862,
0.09823757,
0.1280126,
0.2280646,
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0.002395599,
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-0.03609591,
0.2935174,
0.2038837,
-0.1330858,
0.2432919,
-0.14168... |
Fetal movements in small-for-dates babies. | Subjective assessment of daily fetal movement rates is a simple clinical guide to fetal well-being. Fetal death is unlikely to occur until rate falls below 10 movements/12 hours whilst a rate of less than 21 movements/12 hours is strongly associated with a small-to-dates fetus and indicates the necessity for further as... | 497,145 | [
-0.2790315,
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-0.4683796,
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0.08829657,
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0.198127,
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0.3273056,
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0.04141972,
0.2832422,
0.1639265,
-0.2008563,
... |
Abortion associated with intrauterine infection by candida albicans. Case report. | A 27-year-old patient who became pregnant whilst fitted with an intrauterine contraceptive device developed an intrauterine Candida albicans infection and aborted. The diagnostic (and other inconspicuous) features of C. Albicans infection in the fetus are described. The presence of the intrauterine contraceptive device... | 497,146 | [
-0.124503,
0.1833756,
0.0282052,
0.07537167,
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0.1322011,
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0.220852,
0.2028318,
0.1185477,
0.359... |
Planar bilayer membranes from pure lipids. | Planar lipid bilayer membranes are formed from mixtures of pure lipids in the absence of non-biological solvents. The solventless bilayers are characterized by a large specific capacitance (586-957 nF/cm2) comparable to that of cell membranes but considerably greater than that of conventional lipid/decane bilayers. Hyd... | 497,184 | [
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0.3445404,
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0.2416047,
0.369177,
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-0.0262726,
... |
A gel filtration approach to the study of ribosome-membrane interactions. | 1. Gel filtration on agarose can be used to investigate ribosome-membrane interactions without exposing the materials to the high, and possibly perturbing, hydrostatic pressures experienced during centrifugation procedures to separate free ribosomes from membrane vesicles. 2. After treatment of microsomes with degranul... | 497,200 | [
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0.1076925,
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0.21458,
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0.06785528,
-0.1729109,
0.5713688,
-0.07295895,
0.02780372,
... |
Kinetic studies on ribosomal proteins assembly in preribosomal particles and ribosomal subunits of mammalian cells. | Proteins were isolated from 80-S preribosomal particles and ribosomal subunits of murine L5178Y cells after short and longer periods of incubation with tritiated amino acids. The labeling patterns of ribosomal proteins were compared by two-dimensional polyacrylamide gel electrophoresis. The analysis of isotopic ratios ... | 497,202 | [
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0.1547474,
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-0.1560278,
-0.04825483,
0.220226,
0.3673566,
0.183988,
0.1143143,
... |
Dissociation of double-stranded poly(I) . poly(C) by cis-diammine-dichloro-Pt(II). | The covalent binding of cis-Pt(NH3)2Cl2 on the double stranded poly(I) . poly(C) induced an irreversible dissociation of the two strands. This dissociation was evidenced mainly by poly(I)-Agarose affinity chromatography which allowed to recover free strands of cis-Pt(NH3)2Cl2-poly(I) from a cis-Pt(NH3)2Cl2-poly(I) . po... | 497,222 | [
-0.13912,
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0.4351117,
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-0... |
Basic nuclear proteins in the aquatic fungus Achlya ambisexualis. | The complement of basic chromosomal proteins in the aquatic fungus Achlya ambisexualis has been characterized. Achlya nuclei contain proteins with electrophoretic mobilities on acetic acid/urea and dodecyl sulphate polyacrylamide gels which are comparable to rabbit kidney histones H3, H4 and H2A. In contrast, the behav... | 497,225 | [
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0.1927947,
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0.1896331,
0.1063303,
-0.415942,
-0.0... |
Density labelling studies of the photocontrol of L-phenylalanine ammonia-lyase in discs of potato (Solanum tuberosum) tuber parenchyme. | The photocontrol of L-phenylalanine ammonia-lyase (EC 4.3.1.5) activity in discs of potato (Solanum tuberosum) tuber parenchyme has been investigated by density labelling with 2H from 2H2O. Labelling of enzyme was measured by analysis of the equilibrium distribution of enzyme activity in CsCl density gradients as a fun... | 497,238 | [
0.381744,
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0.1536932,
0.4252548,
0.4399364,
-0.2967628,
0.12... |
Parvalbumins from the lungfish (Protopterus dolloi). | Five parvalbumins have been isolated from the white muscles of the lungfish. They can be divided into two sub families showing typical amino acid compositions, C-terminal amino acid residues, peptide maps and immuno-reactivity. The red muscles including the cardiac muscle also contain parvalbumins in amounts roughly in... | 497,249 | [
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0.3669685,
0.3302593,
0.02017974,
0.2168836,
0.3337863,
-0.2001217,
... |
The structure of two-dimensional scalar fields with applications to vision. | Two-dimensional scalar fields (e. g. pictures) are often described by way of a linear superposition of simple base functions. It is argued that such decompositions are often unnatural in the sense that the decomposition takes no regard of the structure of the field and it may happen that the parts are more complicated ... | 497,260 | [
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0.1120223,
0.4585236,
0.08707922,
-0.1940607... |
[Inhibitors of cathepsin R (ribosomal proteinase). Polyamines as natural inhibitors of the proteinase]. | The effects of potential inhibitors on the activity of neutral ribosomal proteinase--cathepsis R--were studied. It was found that cathepsin R belongs to the group of serine enzymes. The polyamines spermine and spermidine, which are inherently present in the ribosomes, are natural reversible inhibitors of cathepsin R. U... | 497,290 | [
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0.58775,
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0.1... |
Lithium-induced hypothyroidism and thyroiditis. | Patients with a preexisting thyroiditis may be particularly susceptible to a rapid onset of lithium-induced hypothyroidism. The evidence for this hypothesis is reviewed and a case report illustrating this phenomena is presented. | 497,306 | [
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0.09038649,
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0.... |
First passage times as environmental safety indicators: carboxyhemoglobin from cigarette smoke. | The concentration of carbon monoxide in the blood of a cigarette smoker varies in response to the frequency and dose of CO delivered by the cigarettes he smokes and by the rate at which CO washes out of his blood. Moments of first passage times or exit times above a nominal threshold can be calculated using a stochasti... | 497,340 | [
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0.1696757,
0.310776,
0.4285973,
0.08732209,
0.1... |
Simultaneous quantitative estimates of several isotopically labelled substances in the picogram range with selected ion monitoring. | The use of a model developed by the authors for the simultaneous quantitative determination of several isotopically labelled substances of the same chemical structure is described in detail for a two substance system. A computational flow chart is included. An example using natural estradiol and 4-[14C] labelled estrad... | 497,358 | [
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0.1714389,
0.4127626,
-0.1518163,
-0.172336,
0... |
Characterization of ethyl substituted fatty acids from lamb subcutaneous triacylglycerols by combined gas chromatography mass spectrometry. | Mid-chain ethyl substituted fatty acids with chain lengths ranging from 10 to 16 carbon atoms were identified in a concentrate of branched chain fatty acids isolated from the triacylglycerol fatty acids of the subcutaneous adipose tissue of barley-fed lambs. The acids were identified by gas chromatography in combinatio... | 497,360 | [
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0.3053689,
0.1773544,
0.3760258,
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-0.... |
A microprocessor controlled mass spectrometer for the fully automated purification and isotopic analysis of breath carbon dioxide. | Breath tests that measure the oxidative utilization of 13C labeled substrates have been shown to be clinically useful, but have failed to gain wide acceptance because of the slow and costly isotopic analysis of the breath samples. Therefore we have developed a fully automated, microprocessor controlled CO2 purification... | 497,361 | [
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0.06357066,
0.1065486,
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-0.175581... |
[Detection of heterogenicity of the lymphoid populations by measuring the diameter of the cells and cell nuclei]. | Some parameters of distribution according to the lymphoid cell and its nuclei size in the peripheral blood, bone marrow, thymus and spleen of healthy rats were studied. A comparative assay revealed population homogeneity for the thymus and bone marrow lymphocytes as well as their mean diameter differences. Mixing of th... | 497,388 | [
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0.5054952,
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0.2034489,
... |
[Electron-microscopic and electron-autoradiographic characteristics of embryonal lung cells in organ cultures]. | Cells of the mouse embryonal lung at early stages of organotypical cultivation were studied by electron microscopy and autoradiography. The electron autoradiography technique allowed the fate of poorly differentiated cells to be elucidated. | 497,390 | [
0.1051201,
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... |
Activated clotting factors in factor IX concentrates. | The precise quantitation of activated factors in human factor IX concentrates has been accomplished with the use of recently developed, specific assays for factors IXa, Xa, and thrombin. The assay for factor IXa, which measures the initial rate of 3H-factor-X activation, was shown to be specific for factor IXa in the c... | 497,395 | [
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0.551734,
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0.2372781,
-0.2202041,
0.... |
Dysphagia following selective vagotomy. | Progression of dysphagia after vagotomy to the stage of complete obstruction due to a peri-oesophageal fibrotic collar needing operation is a rare event. Review of the 4 such cases previously described, all needing further operation and all after truncal vagotomy, indicates that the oesophageal mucosa was normal on oes... | 497,642 | [
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0.2878541,
-0.05573... |
A 10-year survey of large bowel carcinoma at Groote Schuur Hospital with particular reference to patients under 30 years of age. | In a 10-year survey of large bowel carcinoma at Groote Schuur Hospital 926 cases were studied retrospectively. A marked difference was seen in both the age of presentation and histological differentiation in two different racial groups. All patients who were 29 years of age or less at the time of presentation have been... | 497,646 | [
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0.... |
Central core disease: clinical and pathological evidence of progression within a family. | A family is described whose members showed different clinical presentations of central core disease. In 4 members the myopathy was congenital and nonprogressive, but in 2, muscle weakness first developed in adult life. Two further members had raised CPK levels without muscle weakness. Muscle weakness in one of the late... | 497,805 | [
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0.3231101,
-0.014462... |
The effects of different photoperiods on circadian 5-HT rhythms in regional brain areas and their modulation by pinealectomy, melatonin and oestradiol. | Differential circadian rhythms in 5-HT levels were found in the hypothalamus and pineal (but not in the cortex, hippocampus or midbrain) in ferrets kept in either long (14 h light/10 h dark) or short (8 h light/16 h dark) photoperiods. 5-HT decreased during the first 6 h of illumination in all areas examined from anima... | 497,810 | [
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0.02871872,
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0.3322107,
0.3418308,
-0.007... |
Early changes in muscle glucose-6-phosphate dehydrogenase activity after denervation: locus and dependence on nerve stump length. | Glucose-6-phosphate dehydrogenase (G6PD) activity of rat diaphragm muscle increased significantly 12 h after intrathoracic ('distal') denervation. Since this change represented one of the earliest known events after loss of innervation, the mechanism of neuronal regulation and the nature of the muscle response were fur... | 497,818 | [
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0.2824016,
0.2611933,
... |
Retinal ganglion cell response to axotomy and nerve growth factor antiserum in the regenerating visual system of the newt (Notophthalmus viridescens): an ultrastructural morphometric analysis. | One 3.0 mg dose of the nerve growth factor antiserum (anti-NGF) injected into the vitreous chamber of the eye at the time of optic nerve transection elicits significant changes in the normal newt (Notophthalmus viridescens) retinal ganglion cell body response to axotomy at 7 and 14 days postaxotomy (DPA). Light microsc... | 497,824 | [
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Effects of storage conditions in vitro on the assay of chick liver glycogen. | 1. The reproducibility of an enzymic method for assaying chick liver glycogen was found to be +/- 1.6%. 2. Storage of liver at either -21 or -70 degrees C for up to 4 weeks, after freezing in liquid nitrogen, had no significant effect on glycogen concentration. However, the concentration of free glucose increased by ab... | 497,871 | [
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0.1898638,
-0.0498573,... |
Effect of deficiencies of single essential amino acids on nitrogen and energy utilisation in chicks. | 1. Diets 50% deficient in single essential amino acids were fed to chicks from day 8 to day 18 after hatching to evaluate body-weight gain, food consumption, body composition, nitrogen (N) and energy utilisation. 2. Body-weight gain was reduced most severely by deficiency of isoleucine followed in decreasing order by t... | 497,874 | [
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0.221117,
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0.4885545,
-0.01176392,
... |
The virus neutralizing activity of antibodies specific to the envelope and nucleocapsid of equine herpesvirus type 1. | Antibodies specific to the envelope or nucleocapsid of the Kentucky-D strain of equine herpesvirus type 1 were isolated from convalescent horse serum by immunoadsorption on cyanogen bromide-activated Sepharose conjugated with equine herpesvirus type 1 envelopes or nucleocapsids, with subsequent elution by glycine buffe... | 497,891 | [
-0.2974635,
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-0.02799904,
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0.1564752,
0.2839322,
-0.02943759,
-0.04346062,
... |
Calcium antagonists and contractile responses in rat vas deferens and guinea pig ileal smooth muscle. | The effect of depletion of extracellular Ca2+ (Ca2+ext) on the loss of responsiveness of the guinea pig ileal longitudinal muscle (g.p.i.l.m.) and the rat vas deferens (r.v.d.) to K+ and cis-2-methyl-4-dimethylaminomethyl-1,3-dioxolane methiodide (CD), and K+ and noradrenaline (NA), has been examined and compared with ... | 497,894 | [
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-0.1703597,
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0.083296,
0.05706493,
0.396834,
0.4518923,
0.1519682,
-0.01258162,
0.1860... |
Ketamine kinetics: decerebrate vs. intact cats. | Pharmacokinetic parameters of a ketamine (10 mg/kg, iv) bolus in decerebrate and intact cats were compared. A two-compartment open model best described the data in both groups. The apparent volume of distribution of the peripheral compartment, the apparent volume of distribution of the drug in the body, and the half-li... | 497,902 | [
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0.0461715,
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0.3222207,
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0.1630442,
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0.0375465,
0.08250222,
... |
The abdominal surgeon and the ureter. | Iatrogenic ureteral injuries are not common but may occur whenever the retroperitoneum is opened. The best time to treat these injuries is when they occur. The abdominal surgeon is responsible for the immediate treatment of ureteral injuries that he causes and should be able to take care of most of them. The author des... | 497,926 | [
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0.01373247,
-0.288571,
0.1600399,
0.1341052,
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0.05124334,
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0.06326228,
0.2398912,
-0.2368132,
0... |
Follicular carcinoma in a thyroglossal duct. | The case of a 24-year-old woman with follicular carcinoma arising de novo in a thyroglossal duct is reported. A review of the literature disclosed seven case reports of thyroglossal duct carcinoma with a mixed papillary-follicular pattern. There are three criteria for the diagnosis of follicular carcinoma of a thyroglo... | 497,935 | [
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-0.1601298,
-0.186856... |
Contributions of hemodynamic monitoring to the treatment of chronic congestive heart failure. | Optimal therapy for congestive cardiac failure requires identification of correctable factors that aggravate it as well as an understanding of its etiology. Increased sympathetic nervous system activity, reduced renal blood flow, and cardiac hypertrophy and dilation are the main compensatory processes that occur in res... | 497,982 | [
-0.1398946,
0.1965282,
-0.2777751,
-0.2352882,
0.2981275,
-0.431638,
0.2125786,
-0.2089947,
-0.3528796,
-0.1628326,
-0.112662,
-0.1423595,
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0.03138582,
-0.4243387,
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-0.2231942,
0.3148589,
0.2179009,
-0.01480254,
-0.06023174,
-0.06854342,
-0.1483882,
... |
Sarcomas in ovarian mucinous tumors: a report of two cases. | Two sarcomas that appeared as distinct solitary nodules in the walls of ovarian mucinous cystic tumors are described. One of the tumors was a fibrosarcoma associated with a mucinous cystadenoma; the other was an undifferentiated sarcoma in a mucinous cystadenocarcinoma. Both patients died within 1 1/2 years of their op... | 498,013 | [
-0.2630363,
-0.1581486,
-0.2892925,
-0.4945719,
-0.07469942,
-0.3549815,
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0.02613528,
0.3037349,
0.01341598,
0.08738651,
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-0.1433382,
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-0.3882848,
-0.101885,
0.1006564,
0.03700975,
0.2994948,
-0.05793873,
-0.1824... |
Cytophotometric studies of the nuclear DNA content in cartilaginous tumors. | The histopathological differentiation between chondromas and low-grade malignant chondrosarcomas can be difficult. For this reason we studied in 37 different cartilaginous tumors the mitotic index and the Feulgen DNA content using a scanning-integration cytophotometric technique. In 23 chondromas the Feulgen DNA conten... | 498,016 | [
-0.1484846,
0.2475582,
-0.2552204,
-0.1527964,
0.1948799,
-0.4981869,
-0.4167901,
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0.2103781,
0.1665805,
-0.005028277,
-0.05034728,
-0.3519757,
-0.1667643,
-0.7174722,
-0.09796287,
-0.05690514,
0.06575114,
-0.09624144,
-0.0621297,
0.4036099,
0.1769792,
-0.05203... |
Cis-diamminedichloride platinum II (DDP) in the treatment of penile carcinoma. | Cis-diamminedichloride platinum II (DDP) was administered to eight patients with epidermoid carcinoma of the penis. Three of six adequately treated patients had an objective response: one patient achieved complete remission of 7 months duration and 2 patients had partial remissions of 8 and 2 months, respectively. DDP ... | 498,030 | [
-0.04170671,
-0.001086835,
-0.1665405,
-0.2227363,
0.09589655,
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0.1122335,
0.2151329,
0.2411385,
0.2067605,
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0.1258254,
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-0.3475419,
0.2018837,
-0.1378729,
-0.01722887,
0.04930975,
0.001280715,
0.070173... |
Acute nonlymphocytic leukemia and acute myeloproliferative syndrome following radiation therapy for non-Hodgkin's lymphoma and chronic lymphocytic leukemia: clinical studies. | Seven cases of acute nonlymphocytic leukemia (ANLL) and one case of a malignant myeloproliferative syndrome have been seen after extensive radiation therapy for non-Hodgkin's lymphoma or chronic lymphocytic leukemia. A myeloproliferative syndrome with abnormalities in granulocytic, erythrocytic, and thrombocytic cell l... | 498,058 | [
-0.1619614,
-0.06951857,
-0.185868,
-0.3432242,
0.1007121,
-0.09049612,
0.04183551,
-0.1812944,
-0.258547,
0.3124918,
0.01698778,
0.3773606,
-0.005633262,
0.1192291,
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0.0193219,
0.1296343,
-0.3258921,
0.2025522,
0.2717011,
0.05652326,
0.03497193,
... |
Ontogeny of the rat hepatic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin and its endocrine indepence. | The ontogeny of the 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) receptor was studied in Sprague-Dawley rats by quantitation of the receptor in liver cytosol using isoelectric focusing in polyacrylamide gel. No differences by sex in the receptor concentration were seen at any of the ages studied. Newborn, 21-day-old, and... | 498,093 | [
0.3032436,
-0.0501199,
0.04121825,
0.002637133,
-0.1436857,
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-0.2329436,
0.06426352,
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0.1332601,
0.2048264,
0.07014178,
0.1060648,
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-0.2238165,
-0.02567819,
0.1955727,
-0.1261167,
0.1761423,
0.4861563,
0.02650825,
0... |
Correlation between glucocorticoid receptor and cytolytic response of murine lymphoid cell lines. | By fusion between murine thymoma lines which are either homozygous (r+/r+ or r-/r-) or hemizygous (r+/r-) for the glucocorticoid receptor structural gene r, hybrid clones have been obtained which carry one, two three, or four copies of the r+ allele. These hybrids contain different amounts of normal glucocorticoid rece... | 498,102 | [
0.1532564,
-0.002186162,
-0.1604485,
-0.1789863,
-0.02198381,
-0.06097779,
0.05315841,
0.1447143,
0.3104549,
0.2617975,
0.161747,
-0.1434831,
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0.2365882,
-0.504598,
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-0.1912373,
-0.06088883,
0.2453894,
0.268841,
0.5463169,
-0.02887319,
0.02210184,
... |
Inhibition of DNA synthesis in cultured lymphocytes and tumor cells by extracts of betel nut, tobacco, and miang leaf, plant substances associated with cancer of the ororespiratory epithelium. | The high incidence of oropharyngeal, esophageal, and laryngeal cancers in certain parts of the world has been ascribed to conjugated tannins found in certain folk medicinal herbs. We extracted miang leaf and betel nut with phosphate-buffered saline (0.14 M NaCl, 0.15 M potassium phosphate buffer, pH 7.4) and found that... | 498,109 | [
0.04824583,
-0.128902,
-0.4516919,
-0.06821359,
0.1475501,
0.07125393,
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0.07275835,
0.2201462,
0.2463982,
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0.1557859,
0.08623074,
-0.0535537,
-0.2520532,
0.7268388,
-0.2755649,
0.1481944,
-0.008863744,
0.6325763,
0.2907958,
0.3126575,
-0.1279128,
... |
Comparative antitumor effects of Corynebacterium parvum, Bordetella pertussis, Bacillus Calmette-Guérin, and levamisole alone or in combination with cyclophosphamide in the CaD2 murine mammary adenocarcinoma system. | The antitumor efficacy of various immune stimulants [Corynebacterium parvum, Bordetella pertussis, and Bacillus Calmette-Guérin (BCG)] and levamisole alone or in conjunction with cyclophosphamide (CY) was studied in the CaD2 mammary adenocarcinoma system using schedules developed previously with C. parvum and CY. Weekl... | 498,111 | [
-0.02993738,
-0.251279,
-0.257821,
-0.4618749,
-0.3525512,
-0.3456082,
-0.1188404,
0.293537,
-0.1374002,
0.3371957,
-0.3478141,
0.3672948,
0.09993444,
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0.07002749,
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-0.09222665,
0.2250603,
0.4919236,
0.4071114,
-0.01942697,
-0.03161558,
... |
Adaptation of Sinclair swine melanoma cells to long-term growth in vitro. | Sinclair swine melanoma usually regresses in vivo. In the present study, swine melanoma cells were adapted to long-term growth in culture. The morphology of cultured melanoma cells ranged from dendritic to cuboidal, similar to that described for human melanoma cells. Doubling times of the swine melanoma cells were also... | 498,121 | [
0.1820183,
-0.348322,
-0.04247566,
-0.02202703,
0.1822239,
-0.4951874,
0.02759976,
0.2162636,
0.1116621,
0.1216305,
-0.01685752,
-0.3352182,
-0.1682617,
-0.4095162,
-0.7770731,
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-0.2566201,
0.4088848,
0.173118,
0.1272541,
0.2067874,
0.1381369,
-0.1577374,
-0.... |
Kidney tumors induced in rats by the antischistosomal drug niridazole. | An increased incidence of kidney tumors was found in MRC rats fed the antischistosomal drug niridazole at four dose levels in the diet. Histologically, the adenomas and adenocarcinomas were solid papillary, clear cell, and tubular types, with the latter type predominating. Seven mesenchymal tumors were found among the ... | 498,126 | [
-0.003738199,
0.05140729,
-0.08220314,
-0.140015,
0.005202644,
-0.1844753,
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0.05920281,
0.1085352,
-0.123472,
-0.005396396,
0.07661299,
0.07092655,
0.2181877,
-0.430694,
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-0.6822932,
0.1372182,
0.2214603,
-0.001442636,
0.01853747,
0.1057401,
-0.1403... |
Effects of hormones on growth and alpha-lactalbumin activity in the transplantable rat mammary tumor MCCLX. | We have examined the growth and differentiation properties of the transplantable mammary tumor line of the A X C rat, MCCLX. The MCCLX tumor grows rapidly and exhibits high activity of the milk protein alpha-lactalbumin (alpha LA) (40% of the level in midlactating mammary gland) during serial passage in estrogen-supple... | 498,129 | [
0.1275712,
-0.1197945,
-0.01803624,
-0.3922629,
-0.02528994,
-0.4362774,
-0.3427067,
-0.1006459,
-0.01760727,
0.1498673,
-0.1499265,
0.5433893,
0.1661584,
0.02552098,
-0.437323,
0.08373708,
-0.4472676,
-0.4233995,
0.03099582,
0.04332418,
0.204981,
0.003095309,
-0.1496203,... |
Alteration in binding of dexamethasone to glucocorticoid receptors in regenerating rat liver after partial hepatectomy. | Changes in binding of dexamethasone (9 alpha-fluoro-11 beta, 17 alpha, 21-trihydroxy-16 alpha-methylpregna-1,4-diene-3,20-dione) to its receptors in regenerating rat liver after 70% hepatectomy were examined. Specific receptors for dexamethasone in the liver remnants of adrenalectomized rats decreased significantly dur... | 498,140 | [
0.01899462,
-0.08527215,
-0.006863188,
-0.2888225,
0.1193182,
-0.1741875,
-0.217102,
0.04605832,
0.08631143,
0.1557897,
0.2926545,
0.005326835,
-0.01697907,
0.05345529,
-0.6484283,
-0.05672755,
-0.4029024,
0.09274375,
0.1612978,
0.4187455,
0.2063556,
0.2102759,
-0.1493111... |
Pharmacokinetics of non-protein-bound platinum species following administration of cis-dichlorodiammineplatinum(II). | The pharmacokinetics of non-protein-bound platinum species derived from cis-dichlorodiammineplatinum(II) (cis-platinum) was studied under a variety of dosing conditions. Following rapid infusions (15-minute) of cis-platinum at 100 mg/m2, the unbound drug declined in a biphasic mode with a mean terminal half-life of 48 ... | 498,151 | [
-0.4269138,
-0.1776646,
-0.2381026,
0.01084253,
0.2319454,
-0.2508713,
-0.3394645,
-0.1568774,
-0.05505349,
0.2156689,
-0.04296661,
-0.1021755,
0.02689246,
0.3317196,
-0.07937951,
-0.1011545,
-0.07924815,
0.3667159,
-0.2770967,
-0.01965712,
0.1959627,
0.3674058,
0.162773,... |
cis-Dichlorodiammineplatinum(II) in non-small cell carcinoma of the lung. | The role of cis-dichlorodiammineplatinum(II) (cis-platinum) as a single agent in non-small cell lung cancer has not been clearly defined, and extensive phase II studies have not been conducted. However, objective responses were noted in several early clinical trials. A review of these reports, including combinations wi... | 498,158 | [
-0.4444039,
-0.2943011,
-0.06339195,
-0.3027683,
0.05755932,
-0.2821997,
-0.456798,
-0.161929,
-0.09708101,
0.1372553,
-0.09792072,
-0.09747183,
-0.1317227,
0.3359995,
-0.1188031,
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0.1587498,
0.3916093,
-0.0462114,
0.08266218,
0.0100296,
0.007979874,
0.01617919... |
Cyto- and synaptogenesis in the arcuate nucleus of the rat hypothalamus during fetal and early postnatal life. | Morphogenesis of the arcuate nucleus of the rat from the 15th fetal day to the 6th postnatal day was investigated light and electron microscopically. The arcuate neurons exhibit a gradual development after the 15th fetal day. All cytoplasmic constituents are present in these nerve cells already during the last days of ... | 498,250 | [
0.1643433,
0.07366063,
-0.1979248,
0.2121139,
0.0643838,
-0.4604438,
-0.3408464,
-0.3285153,
0.3146868,
0.2187328,
0.007688122,
0.2953114,
0.07731051,
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0.5140309,
0.1468938,
0.1342524,
0.2468958,
0.3980154,
0.02263221,
-0.... |
Observations on the origins of plasma membrane in rat deciduoma. | An NADH-ferricyanide reductase activity resistant to inactivation by cytochemical procedures was examined during decidualization of rat endometrium. Resistant activity was restricted to plasma membranes, distal elements of the Golgi apparatus, and discoid cisternae and cytoplasmic vesicles of decidual cells of endometr... | 498,252 | [
-0.1637572,
0.03663932,
-0.1494418,
0.2923297,
0.1883472,
-0.3689006,
0.320059,
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0.2340083,
0.532232,
0.03974035,
-0.03316592,
-0.0551004,
0.07407529,
-0.2971991,
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-0.3316594,
-0.0780678,
-0.08846851,
-0.2992942,
0.3235871,
0.3938871,
0.1349777,
... |
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