title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Repetitive sequences in protein A from Staphylococcus aureus. Arrangement of five regions within the protein, four being highly homologous and Fc-binding. | After tryptic digestion of intact Staphylococcus aureus the residual portion of protein A that was still bound to the cell wall was cleaved off with lysostaphin. From the two digests Fc-binding fragments were isolated and the following characteristics observed. (a) There are four Fc-binding, highly homologous regions, ... | 557,409 | [
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Action of bull seminal vesicle ribonuclease on mouse leukaemic cells BP-8 and EL-4. | Bull seminal vesicle ribonuclease, when added in vitro to the suspension of ascitic leukaemic cells EL-4 and BP-8 for 2 hours at 37 degrees C and then transplanted to the abdominal cavities of mice, inhibitied the proliferation of these cells in vivo. When the temperature of the medium was decreased to 25 degrees C, AS... | 557,422 | [
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Melanosomes of pigmented basal cell epithelioma. | Electron microscopic examination of a pigmented basal cell epithelioma of scrotal skin revealed many tumor cells and melanocytes which were laden with large packages of melanosomes. In tumor cells these packages were delimited by either single- or double-limiting membranes or were not membrane bound. The matrix of thes... | 557,423 | [
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Dominance and environmental variances: their effect on heritabilities estimated from twin data. | A method for partitioning genetic variance estimated from twin data into additive and dominance variances was presented using Falconer's variance component model. The effects of dominance and environmental variances on a number of heritability estimates were also reviewed. A heritability estimate, based on the analysis... | 557,450 | [
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[Preoperative infusion therapy in childhood. I. Initial conditions and principles]. | Infusion therapy for purposes of surgery differs significantly from the infusion requirements for "conservative" purposes, in adults as well as in infants and children. The preoperative situation of infants and children undergoing usual surgical procedures is particularly characterized by 1. the physiological condition... | 557,453 | [
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Determination of serum proteins in the presence of dextran by means of the biuret reaction. | 264 biuret reagents for total protein determination in serum containing dextran were investigated. The usefulness of the method is dependent on proper ratio of the components of the reagent: concentrations of NaOH and copper sulphate, and the ratio of sodium-potassium tartrate to copper sulphate. | 557,456 | [
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Zinc protoporphyrin level in blood determined by a portable hematofluorometer: a screening device for lead poisoning. | An inexpensive portable fluorometer has been designed which can be used to determine the concentration of zinc protoporphyrin (ZPP) in a drop of unprocessed blood deposited on a disposable glass slide. No volume measurement of the blood sample need be made. The instrument displays the ZPP level in micrograms per decili... | 557,519 | [
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Nitrones. 7. alpha-Quinoxalinyl-N-substituted nitrone 1,4-dioxides. | A series of alpha-quinoxalinyl-N-substitute nitrone 1,4-dioxides has been synthesize and evaluated as antibacterial and antiprotozoal agents. Structure-activity relationships are discussed. Of the compounds tested, alpha-(3-methyl-2-quinoxalinyl)-N-methylnitrone 1,4-dioxide (2) was the most active agent in vivo against... | 557,559 | [
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4-Halovinyl- and 4-ethynyl-4-deformylpyridoxal derivatives and related analogues as potentially irreversible antagonists of vitamin B6. | Analogues of pyridoxal bearing alpha- and beta-chlorovinyl, beta-bromovinyl, butadienyl, acetyl, and 1-butenyl groups in place of the formyl group have been synthesized by subjecting 3,alpha5-di-O-benzylpyridoxal to appropriate Wittig or Grignard reactions. Similar methods yielded one-carbon homologues of pyridoxal and... | 557,561 | [
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The nonpolar egg wax lipids of the cattle tick, Boophilus microplus (canestrini). | About 40% of the lipids of the egg wax of Boophilus microplus are nonpolar and comprise hydrocarbons (10%) and wax esters (90%). The hydrocarbon fraction is 87% unbranched alkanes, the major components being n-nonadecane (10.8%), n-eicosane (12.1%), and n-heneicosane (9.8%). This fraction also contains 2,4,6-cholestatr... | 557,717 | [
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[Simplfied technique of lumbar subarachnoid-peritoneal shunt (author's transl)]. | The authors have developed a simplified technique of lumbar subarachnoid peritoneal shunt in which the spinal tube is easily introduced through a puncture needle without doing a laminectomy. Seventeen cases of communicating hydrocephalus of various orgin have been treated by this procedure. In this paper, we reported o... | 557,743 | [
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Brain lesions that produce delta waves in the EEG. | Localized delta activity appears in cortex overlying a circumscribed white matter lesion. Less commonly, localized delta activity may result from a localized thalamic lesion. Unilateral diffuse delta activity appears on the side of thalamic or hypothalamic lesions. Bilateral delta activity results from bilateral lesion... | 557,774 | [
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Alcohol drinking: abnormal intake caused by tetrahydropapaveroline in brain. | Tetrahydropapaveroline (THP), a dopamine-dopaldehyde condensation product, was delivered directly into the cerebral ventricle of rats automatically every 15 minutes for 12 days. The animals were given access to both water and ethylalcohol, the latter being presented in 12 concentrations from 3 to 30 percent. Within 3 t... | 557,839 | [
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Cerebral necrosis following irradiation and chemotherapy for metastatic choriocarcinoma. | A case of cerebral necrosis following radiation and chemotherapy in a patient with metastatic cerebral choriocarcinoma is reported. Computed tomography (EMI Scan) demonstrated evolution and enlargement of the necrotic lesion. This focus was surgically excised and histology is presented. The possible enhancement of radi... | 557,845 | [
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Acyclicity and dyscyclicity in mares. | Two trotter stud farms were visited on Mondays, Wednesdays, and Fridays during 1972 and 1973. A total of 356 mares were bored on these farms during these breeding seasons. There were 194 nursing, 113 barren, and 49 maiden mares. Of the 356 mares, 78 (21.9%) had functional disorders of the ovaries at one time or another... | 557,851 | [
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Clinical results of lumbar sympathectomy alone or as a complement of direct arterial surgery. | Six hundred and eighty patients underwent conservative surgery for chronic obliterative arterial disease of the lower limbs during a 15 year period ranging from 1960 to 1974. Two hundred and fifty-three lumbar sympathectomy were performed in 240 patients, 339 patients had direct surgery and in 133 cases lumbar sympathe... | 557,864 | [
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Pathogenesis of developmental defects induced in the rat by amniotic sac puncture. | The morphogenesis of developmental defects induced by aminotic sac puncture was studied at the gross and microscopic levels. In fetuses recovered from 15 min to 48 h after amniocentesis, a pattern of hemorrhagic lesions, excessive accumulation of interstitial fluid, followed by tissue necrosis and leading ultimately t... | 557,867 | [
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Comparative sensitivities of viruses to cell cultures and transport media. | The relative sensitivities and temporal permissivenesses of human embryonic kidney, baboon kidney, and human fibroblast (WI-38) cells for primary isolation of viruses were compared. Of 405 viruses isolated, 83% (335) were cultivated in human embryonic kidney cells, and 49% (198) in baboon kidney cells. WI-38 cells supp... | 557,895 | [
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Foodborne disease outbreaks of chemical etiology in the United States, 1970-1974. | In the United States between 1970 and 1974 there was an increase each year both in the absolute number of foodborne diseases outbreaks of chemical etiology reported to the Center for Disease Control and in the proportion of these outbreaks in the total reported foodborne disease outbreaks. Nearly half (48.9%) of these ... | 557,897 | [
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Plasma beta-subunit human chorionic gonadotropin assay in molar pregnancy and choriocarcinoma. | Serum plasma levels of the beta-subunit of human chorionic gonadotropin (HCG-beta) were measured by radioimmunoassay in 24 women with molar pregnancies and five with choriocarcinoma. In the patients with molar pregnancy, plasma HCG-beta concentrations became undetectable within 8 to 173 days. In the patients with chori... | 557,901 | [
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A comparison of general anesthesia and lumbar epidural analgesia for elective cesarean section. | Controversy exists concerning the choice of anesthetic technic for elective cesarean section. Several maternal and newborn parameters were compared during general anesthesia (GA) and lumbar epidural analgesia (LEA). High inspired maternal O2 levels were achieved with both technics. Vigorous, well-oxygenated infants wit... | 557,920 | [
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Elective splenectomy in the elderly patient. | This report reviews 10 years' experience with elective splenectomy in patients over 55 years of age. Of 55 patients, 25 were over the age of 65. The majority of splenectomies (41) were performed for hematological disorders exclusive of lymphoma, but including ITP, hypersplenism (both primary and secondary), Felty's syn... | 557,944 | [
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Compartmentation of free amino acids for protein biosynthesis. Influence of diurnal changes in hepatic amino acid concentrations of the composition of the precursor pool charging aminoacyl-transfer ribonucleic acid. | To investigate further the mechanisms by which amino acids are segregated for protein biosynthesis, the distribution of a pulse of [3H]valine was monitored in hepatic amino acid pools at seven intervals in the diurnal cycle of meal-fed rats. Although each condition was characterized by a unique balance between intracel... | 557,977 | [
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Fluorescence properties of the copper enzyme galactose oxidase and its tryptophan-modified derivatives. | Galactose oxidase contains a single nonblue Cu(II) atom and 18 tryptophan residues per molecule. Removal of the copper atom reveals that it has an approximately 29% quenching effect on the relative quantum yield of fluorescence. While saturating concentrations of the sugar substrate of galactose oxidase also reduce the... | 557,987 | [
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Calorimetric measurements of the transition enthalpy of DNA in aqueous urea solutions. | The helix-coil equilibrium of DNA is delicately affected by the nature of the solvent. In this investigation the helical secondary structure was destabilized by an increasing concentration of urea. We found a linear dependence of the transition enthalpy deltaH on the urea concentration for calf thymus DNA as well as fo... | 557,993 | [
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Characterisation of a highly hydrophobically modified lactate dehydrogenase. | 1. Lysine residues of porcine H4 lactate dehydrogenase (L-lactate:NAD+ oxidoreductase EC 1.1.1.27) were modified with methyl-epsilon-(N-2,4-dinitrophenyl)aminocaproimidate - HCl. With increasing incorporation of the reagent a linear decrease of enzymatic activity was noticed. No essential lysyl group with an extraordin... | 557,996 | [
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[Study of lysosomal enzymes in chick embryo fibroblasts infected with microorganisms of family Halprowiaceae (Chlamydiaceae)]. | It is shown that infection of chick embryo fibroblasts with agents of paratrachoma and meningopneumonia Halprowiaceae (Chlamydiaceae) causes a sharp decrease of the activities of lysosomal enzymes, e.g. acidic alpha-glucosidase, beta-glucuronidase, beta-galactosidase, alpha-mannosidase, acid phosphatase, etc. The activ... | 557,998 | [
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[Fractionation of "tricholysine" by isoelectric focusing]. | A possibility to fractionate fibrinolytically and thrombolytically active complex "tricholysin" into five components, differing in iso-points and in enzymatic activity, is demonstrated by means of isoelectric focusing using ampholine solution within pH range 3.0-10.0. Homogenous fraction IV (isopoint 6.8-7.0) has a low... | 557,999 | [
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0.09942684,
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0.... |
Ultracentrifugation of hydrated egg lecithin in benzene solution. | Estimations of molecular weights from sedimentation equilibrium experiments indicate that the degree of aggregation of egg lecithin in benzene solutions increases with increasing addition of water. The molecular weight rises monotopically from about 14,000 in the anhydrous state to about 57,000 at a water/lecithin rati... | 558,059 | [
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Septicemia and meningoencephalitis in pastured cattle caused by a Haemophilus-like organism ("Haemophilus somnus"). | Septicemia and meningoencephalitis developed in 10 pastured cattle 7 months to 3 years of age. Two unrelated herds were involved. Necropsy findings were similar to those previously reported in cattle infected with a Haemophilus-like organism, including multifocal intramuscular hemorrhages, suppurative polyarthritis, an... | 558,084 | [
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The structure of mesokaryote chromosome. | Condensed and dispersed forms of the chromosomes of the dinoflagellate, Prorocentrum micans, deposited on grids by the microcentrifugation technique were studied by electron microscopy. In the normally condensed form, the chromosomes appear as banded rods surrounded by a peripheral cloud of partially dispersed fibers. ... | 558,086 | [
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0.15198... |
Effect of iron and protein deficiency on the expulsion of Nippostrongylus brasiliensis from the small intestine of the rat. | The relationship between iron deficiency and protein deficiency and infestation of the rat with the nematode Nippostrongylus brasiliensis was investigated. There was a significant delay in the expulsion of N. brasiliensis from the small intestine of both iron deficient and protein deficient animals and those with a com... | 558,135 | [
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[The use of human albumin in infusion therapy]. | A survey on physiologic functions of albumin is given. Furthermore the two main-indications of albumin, the treatment of blood-volume-deficiency, including the use of albumin for the iso-volemic-hemodilution and the substitution in hyproteinemia are discussed. A comparison of albumin and plasmaproteinsolution follows. ... | 558,157 | [
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[The manufacture and transfusion of deep frozen preserved blood]. | For the past ten years we have been evaluating the preservation of human red cells by freezing. A comparative study of several techniques revealed no major differences as far as clinical effectiveness is concerned. The recovery percentage varies from 90-95%. Due to the washing procedure, necessary for removing the intr... | 558,164 | [
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[Transfusion problems relative to the HL-A system]. | The importance of the HL-A system for blood transfusions (febrile reactions, substitution of leukocytes and platelets, prevention of anti-HL-A immunisation) is described. Furthermore, the problem of finding an HL-A identical donor for a given recipient which arises from the polymorphism of the HL-A system is discussed. | 558,167 | [
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Synthesis of myelin glycosphingolipids (galactosylceramide and galactosyl(3-O-sulfate)ceramide (sulfatide)) by cloned cell lines derived from mouse neurotumors. | Clonal cell lines derived from both spontaneous and chemically induced rat and mouse brain tumors were screened for their ability to incorporate H232SO4 into galactosyl(3-O-sulfate)ceramide (sulfatide). High levels of 35SO4 incorporation into sulfatide were found only in two of the mouse cell lines studied (G26-20 and ... | 558,188 | [
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Plasma tryptophan levels and brain serotonin metabolism in chronically uremic rats. | Plasma tryptophan (Trp) levels and brain concentrations of Trp, serotonin, and 5-hydroxyindoleacetic acid (5-HIAA) were measured in chronically uremic rats fed either 11% or 18% casein diets for 8 to 12 weeks. Uremic rats had increased levels of plasma urea nitrogen and 5-HIAA when compared with sham-operated pair-fed ... | 558,284 | [
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Clinical pharmacology of methicillin in neonates. | The pharmacokinetic properties of methicillin were investigated in 59 newborn infants. Concentrations of methicillin in serum were approximately 58 and 80 microng/ml at one hour after 25 and 50 mg/kg doses, respectively. The average serum half-life values ranged from one to three hours and were inversely correlated wit... | 558,302 | [
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A guide to research on the Rorschach prognostic rating scale. | Research on the Rorschach Prognostic Rating Scale done in the last 25 years is summarized. The study results are organized into six topics: ability to predict outcome, numerical correlations, populations differentiated, populations not differentiated, specific therapies. The scale significantly predicts outcome and is ... | 558,308 | [
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Comparison of the effects of morphine on locomotor activity, analgesia and primary and protracted physical dependence in six mouse strains. | Mice of the DBA/2J, A/J, C3H, C57BL/L, ICR and Swiss strains were studied with respect to acute and chronic morphine administration. The acute administration of morphine resulted in a dose-dependent running response in C57BL/6, C3H, ICR and Swiss strains, but no running response in DBA/2J and A/J strains. Strain differ... | 558,328 | [
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Hysterography and Hysteroscopy in the infertile patient. | Hysterography and hysteroscopy are diagnostic techniques currently utilized in searching for intrauterine defects that can cause infertility. The purpose of this paper is to describe the basic procedures, discuss their indications and compare results obtained in the infertile patient. | 558,334 | [
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A suggested schema for utilization review for a Community Mental Health Center. | Three record-keeping models were examined by an interdisciplinary committee at the Rochester Mental Health Center to see which would best meet the needs for a standardized record format that could be used by an outpatient comprehensive community mental health center. The systems examined were: (1) Model Criteria Set, (... | 558,336 | [
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Control of protein synthesis in Semliki forest virus-infected cells. | Protein synthesis in Semliki forest virus-infected chicken embryo cells was studied by labeling them with [35S]methionine for short periods at different times after infection, with or without synchronization of protein synthesis by the hypertonic block technique. The rate of host-cell protein synthesis declined almost ... | 558,342 | [
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[Acrocephalopolysyndactyly (type II (McKusick) acrocephalosyndactyly or Carpenter's syndrome. Report on 4 cases and an observation of the syndrome of Marshall-Smith (author's transl)]. | Four observations of Carpenter's Syndrome, two siblings and two unrelated children, and a case of Marshall-Smith's Syndrome are reported, all sharing duplication of the terminal phalanx of the big toe and a dyskephaly. Carpenter's Syndrome has been noted in at least 27 cases inheritance; is autosomalcessive. Main featu... | 558,466 | [
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Field estimation of VO2 max in children eight years of age. | The purpose of the investigation was to explore the validity of using timed distance runs as predictorr of cardiorespiratory fitness in young untrained children. Maximal oxygen consumption and performance in runs of 549, 1207, and 1609 meters (600 yards, 3/4 mile, and 1 mile) were compared in 38 children eight years of... | 558,493 | [
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Quantitative assessment of tolerance to and dependence on morphine in mice. | 1. Tolerance to morphine-induced analgesia (hot plate and acetic acid whrithing test), hypothermia and lethality can be quantified in mice by measuring the degree of parallel shifts of semilog. dose-response relationships induced by repeated opioid administration. 2. A similar procedure can be used for the quantificati... | 558,528 | [
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... |
The in vivo development of plasma cells: a morphologic study of human cerebrospinal fluid. | This is a case study of a patient with the clinical diagnosis of meningoencephalitis. It demonstrates the in vivo development of plasma cells in the central nervous system. All the stages of in vitro mitogen-induced lymphocyte transformation previously described by light and electron microscopy are recapitulated in thi... | 558,550 | [
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Neurologic complications of cardiac catheterization. | A retrospective survey was made of neurologic complications of cardiac catheterization. Of 10 patients, only one had a diffuse disorder, with seizures of a type associated with reaction to contrast agents. Disorders in the other nine patients appeared to be embolic in nature. Five of these nine involved deficits indica... | 558,558 | [
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A simple method for beveling micropipettes for intracellular recording and current injection. | A simple equipment for beveling intracellular microelectrodes has been made by modifying a conventional turntable. An agar disc containing ceric oxide polishing compound which was put on a flat glass disc was found to be suitable for beveling of Pyrex single- and double-barreled micropipette electrodes with a tip diame... | 558,588 | [
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... |
Stress relaxation compared with relaxation after contraction in smooth muscles. | The time courses of relaxation after contraction and of stress relaxation were found to be different. In the first case, but not in the latter, the time curves have a sigmoid shape. Furthermore, stress relaxation is characterized by a remaining higher resting tension. The differences can be explained by different funct... | 558,592 | [
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The influence of the position of the oxygen dissociation curve on oxygen-dependent functions of the isolated perfused rat liver. III. Studies at different levels of anaemic hypoxia. | The influence of a 2,3-diphosphoglycerate (2,3-DPG)-induced displacement of the oxygen dissociation curve (O.D.C.) on the isolated perfused rat liver was studied at different levels of anaemic hypoxia. Rat livers were perfused either with fresh or with 2,3-DPG-depleted human erythrocytes at different haematocrit values... | 558,600 | [
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Deficits in food and water intake after knife cuts that deplete striatal DA or hypothalamic NE in rats. | Knife cuts ventral or medial to the striatum were used to interrupt some of the principal connections of this structure. All of the cuts depleted striatal dopamine and produced aphagia and adipsia but there was no indication that the two classes of effects were always correlated. Cuts medial to the striatum produced th... | 558,621 | [
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A study of agoraphobic housewives. | Thirty married agoraphobic women referred to out-patient clinics in Edinburgh were compared with 'normal' controls (selected from GP records and screened for the absence of psychiatric symptoms) matched on age, sex social class and marital status. The agoraphobics' husbands were similarly compared with the husbands of ... | 558,626 | [
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0.06827845,
-0.075269... |
Hypothalamic self-stimulation under the chronic morphine treatment in the rat. | The influence of morphine on self-stimulation (SS) under chronic morphine administration (30 injections for 15 days) in increasing doses (from 20 to 20 mg/kg/injection) has been studied. Initial doses had a depressive effect varying in degree in different animals. Subsequent injections activated "reward" behavior. This... | 558,644 | [
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0.02466691,
0.05320326,
0.0112297,
0.205679... |
The use of multivariable standard curves in the radioimmunoassay of testosterone and 5alpha-dihydrotestosterone. | Multivariable calibration curves have been used to enable testosterone and 5alpha-dihydrotestosterone to be assayed directly in plasma extracts without further pre-purification of the sample. Two antisera were used, both with relatively high, but different affinities for the substances measured, and with relatively low... | 558,665 | [
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[Participation of the hippocampus in regulating a pathologic inactive motor reaction in dogs]. | A local pathological inert motor reaction, involving a forced flexion of the forepaw, was formed after simultaneous stimulation with NaCl solution of a part of the tongue brought out to the cheek and electrical stimulation of the forepaw. The reaction decreased (by 70 to 80%) after electrical stimulation of the dorsal ... | 558,694 | [
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[Biological properties of 1,2-benzisothiazole compounds. Spasmolytic effect of N-(cyclohexylaminoethyl)-1,2-benzisothiazole-3-carboxyamides benzene-substituted on segments of human myometrium in virto]. | A report is given on the spasmolytic effect of two benzisothiazolcarboxyamides (compound A and compound B). These drugs were able to inhibit the stimulant action of histamine on human isolated myometrium. The potency of the two compounds exceeded by ten times that of ritodrine (a beta adrenergic stimulant), the efficac... | 558,765 | [
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Radioimmunoassay of vinblastine and vincristine. | 1 The cytotoxic agent, vinblastine, was conjugated to albumin, using the Mannich reaction. Rabbits immunized with two conjugates, containing differing amounts of hapten, produce antibodies which bound [3H]-vinblastine. 2 Antisera from one rabbit cross-reacted with both vinblastine and vincristine and were used to devel... | 558,786 | [
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Interaction of DNA with poly(L-Lys-L-Ala-Gly) and poly(L-Lys-L-Ala-L-Pro). Circular dichroism and thermal denaturation studies. | Complexes of DNA with polypeptides composed of Lys, Ala, and Gly in both a sequential order, poly(L-lysine-L-alanine-glycine), and a statistical distribution, poly(L-lysine36-L-alanine28-glycine), were prepared using gradient dialysis. These polypeptide-DNA complexes were studied using ultraviolet absorption (UV) and c... | 558,795 | [
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Reconstitution of bovine procarboxypeptidase A-S6 from the free subunits. | The three subunits I, II, and III of bovine procarboxypeptidase A separated by reversible dimethylmaleylation can reassociate to form the reconstituted complexes I + II, I + III, and I + II + III. Since the association II + III is not possible, subunit I appears to play a central role in the formation of the complex. I... | 558,800 | [
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Distinct properties of uridine transport systems in growing, quiescent and serum-stimulated hamster embryo cells. | The kinetics of uridine uptake in growing, quiescent and serum-activated hamster embryo cells are investigated. The maximum velocity of uridine uptake in growing hamster embryo cells, is lower than in the methylcholanthrene transformed hamster cell line (MCT). This kinetic constant is further reduced in quiescent cells... | 558,801 | [
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Ultrasound scanning in the radiotherapy department. | Apart from its use by diagnostic radiologists in the detection and staging of tumours, ultrasound scanning appears to offer particular advantages to the radiotherapist in treatment field planning. The following merits are almost self-evident: tumour, organ and body outlines are visualised, with the patient usually in t... | 558,861 | [
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Comparison of the production rates of bacteria in the rumen estimated by using labelled live and formaldehyde treated mixed bacterial cells. | The bacteria production rates in the rumen have been estimated by injecting 14C- and 35S-labelled mixed rumen bacteria, either live or killed by treatment with formaldehyde, into the rumen and applying isotope dilution technique. The rate of bacteria production when estimated by using either live- or dead-(protected-)l... | 558,908 | [
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Genetic analysis of a strain of mice plateaued for litter size. | A strain of mice (S1) was successfully selected for large litter size for 31 generations, increasing the mean by 4.2 young per litter. After generation 31, there was no further progress and it was concluded that a selection plateau had been reached. Realized heritability decreased during the course of the experiment fr... | 558,934 | [
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Influence of flow velocity and cell concentration on dynamic adhesion of erythrocytes to glass surface. | Comparative studies were carried out on dynamic adhesion of 51Cr-labelled erythrocytes to the surface of glass beads in the presence of serum in the medium (50 microng of protein/ml) and in protein-free medium. The influence of cell concentration (within the range 4 X 10(5) to 8 X 10(6)/ml) and of cellular flow velocit... | 558,991 | [
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Some effects of mating in female tsetse, Glossina austeni Newst. | Virgin females of G. austeni were mated at carefully chosen physiological states to determine the effect of mating on ovulation, neurosecretion and blood meal size. The results suggest that ovulation and larviposition are controlled by neurosecretion, and that the release of neurosecretion requires both a mating stimul... | 559,060 | [
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The applicability of inescapable shock as a source of animal depression. | Male rats (N = 27) were given initial experience with escapable shock, equivalent amounts of inescapable shock, or no shock. Measures were then obtained in the ensuing 15 hours on food intake, water intake, number of cage crossings, and weight change for all groups. Following this, animals were tested on an escape task... | 559,062 | [
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0.1279238,
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0.1502923... |
Revision of Mediorhynchus van cleave 1916 (acanthocephala) with a key to species. | Species characters in Mediorhynchus are discussed, and a consistent method of describing hook arrangement, longitudinal rows, is proposed. Mediorhynchus papillosus Van Cleave 1916, and M. orientalis Belopol'skaya 1953 are redescribed, and M. edmondsi sp. n. is described from Palawan. The new species is most similar to ... | 559,066 | [
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0.0313... |
The breeding system of Polysphondylium pallidum, a cellular slime mold. | A mating type analysis was performed on 231 isolates of the cellular slime mold, Polysphondylium pallidum found in 61 samples collected in eastern North America between northern Florida and sourthern Canada. Seventy-eight percent of the isolates belonged to one of 2 mating types; 18% were incapable of mating with any p... | 559,083 | [
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[Online CRT visual masking system]. | To analyse the human visual perception process by backward masking, thousands of TS's and MS's must be exposed even in an experiment. If a mechanical tachistoscope should be used, labors for making such stimuli, for changing them at each exposure and for arranging data of the S's reaction would be exceedingly great. In... | 559,191 | [
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PSRO and the dissolution of the malpractice suit. | The effect of PSRO on the practice of defensive medicine and the effect of the civil immunity provision on the numbers of malpractice suits may well be substantial. Cost savings in terms of control of overutilization and of the potential for patient injury engendered by that overutilization will ensue. While substantia... | 559,227 | [
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Evidence against mutational "hot-spots" at aggregation loci in Dictyostelium discoideum. | Complementation tests were performed on 10 strains of Dictyostelium discoideum which carry developmental mutations representing aggregation loci identified previously in two independent studies. When the 5 aggregation-deficient strains representing loci CGI-5 were fused with the 5 strains carrying mutations at loci ago... | 559,242 | [
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Nonhypoxemic hazards of prolonged myoclonus. | Hyperkalemia, hyperthermia, and systemic hypotension developed in a patient with generalized myoclonus. These disorders reached life-threatening proportions but were rapidly and completely corrected after the patient was paralyzed with pharmacologic agents. Induced neuromuscular blockade may be indicated when the syste... | 559,261 | [
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Retrobulbar neuritis. In vitro evidence of sensitization to myelin basic protein in patients without multiple sclerosis. | Thirty-six normal subjects and 34 patients with retrobulbar neuritis were studied with use of the technique of macrophage migration inhibition factor assay and myelin basic protein as antigen. Serial studies were carried out when possible. Normal subjects gave a mean migration index of 100.9+/-9. Eleven patients with r... | 559,264 | [
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Normal cerebral arteriography in patients with spontaneous subarachnoid hemorrhage. | Previous studies have reported that 18 to 27% of patients with spontaneous subarachnoid hemorrhage have normal cerebral arteriograms. Our series of 220 patients from three hospitals demonstrated normal arteriograms in only 16 (7%). Recent improvements in neuroradiologic techniques, such as femoral catheterization, magn... | 559,271 | [
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Studies on the lithium transport across the red cell membrane. III. Factors contributing to the intraindividual variability of the in vitro Li+ distribution across the human red cell membrane. | 1. Extracellular potassium bicarbonate, ouabain, dipyridamole and the Na+ distribution between red cells and plasma influence Li+ transport across the human red cell membrane. The significance of these parameters for the intraindividual variability of the steady-state ratio of external to internal Li+ was studied in vi... | 559,291 | [
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Effects of verapamil on excitation-contraction coupling in single crab muscle fibers. | The effects of verapamil and its optical isomers on the electrical and mechanical characteristics of single muscle fibers of Callinectes danae were studied. Verapamil (10-20 microng/ml) blocked the procaine- and TEA-induced spikes; the blockade was preceded by reduction in the rate of rise of the upstroke and increase ... | 559,294 | [
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[Treatment of arterial hypertension with propranolol in pregnant women. 10 cases]. | Ten hypertensive patients were treated with propranolol throughout pregnancy. Propranolol had a favorable effect on blood pressure and perhaps on other signs of pre-eclampsia too. No increase in uterine contractility, causing premature delivery, was noted. Weight at birth and APGAR index in infants was apparently not u... | 559,299 | [
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[Quantitative characteristics of serum antitryptic activity]. | The method suggested includes incubation of trypsin with native blood serum and subsequent quantitative determination of trypsin, that did not react with inhibitor, by means of the antitryptic precipitating serum. The method is based on the principle of radial immunodiffusion. In native serum that was not subjected to ... | 559,362 | [
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Germ cell tumors of the testes. | Most malignant testicular neoplasms are of germ cell origin. They are divided into five basic types: seminomas, embryonal carcinomas, teratocarcinomas, adult teratomas and choriocarcinomas. Clinically they may present as an enlarging testicular mass, or with symptoms resulting from metastases or hormonal secretions. Th... | 559,372 | [
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0.1930903,
0.1657238,
-0.249984... |
[Effect of prolonged alcoholization on the cerebral electical activity and emotional behavior of rats]. | Two stages of alcohol intoxication were detected in an experiment on 21 rats during formation of addiction to alcohol. It has been shown that the emotiogenic hypothalamic zones may play the part of trigger mechanisms with infolvement of limbic and neocortical apparatuses. At the same time a different type of integratio... | 559,380 | [
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Diagnosis of intestinal parasitic infestation. Study of two methods for collection of specimens. | Two methods for collecting fecal specimens for parasitologic examination were compared: the usual samples from different days to be studied separately ("triads") and the alternate procedure of mixing three daily specimens in a single flask with thimerosal-iodine-formaldehyde as preservative ("blend"), in order to save ... | 559,409 | [
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0.3482823,
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0.2437378,
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... |
Faulty anesthesia circuits: a source of environmental pollution in the operating room. | Commonly used disposable anesthesia circuits were studied for leak and gas spillage. Trace anesthetic gas concentrations produced by these circuits in the anesthesiologist's breathing zone were analyzed by a Hewlett-Packard Gas Chromatograph. These measurements demonstrated ambient halothane (3.29 +/- 0.1 ppm) and N2O ... | 559,434 | [
0.03381952,
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0.007477025,
0.1104924,
-0.1433382,
0.2005754,
0.07047062,
-0.06321581,
-0.1134631,
-0.02044055,
-0.06962273,
-0.4963674,
-0.1403853,
0.2133079,
-0.3869155,
-0.1141114,
0.09515461,
-0.062... |
Some characteristics of an exceptionally potent inhaled anesthetic: thiomethoxyflurane. | The authors sought to test whether a deviation existed for the correlation between anesthetic potency and the oil/gas partition coefficient at an extreme of lipid solubility. For thiomethoxyflurane, the sulfur analog of methoxyflurane, the oil/gas partition coefficient was 7230 +/- 50 SEM, and MAC (minimum alveolar con... | 559,438 | [
-0.1937443,
0.1841994,
-0.1293786,
-0.7120758,
0.06800622,
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0.2058951,
0.04419475,
0.2611995,
0.01580839,
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0.08360334,
0.3403443,
0.6456383,
-0.02287303,
0.100049,
-0.07397894,
... |
Eversion of upper eyelids. | Tarsorrhaphy was effective in correcting a case of bilateral total eversion of the upper eyelids in a newborn infant. | 559,466 | [
-0.194176,
-0.1249658,
-0.3264095,
-0.1720241,
0.2208643,
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0.1502539,
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0.3015645,
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0.07798489,
-0.02430077,
0.0486895,
... |
Primary cutaneous phaeohyphomycosis caused by Drechslera spicifera. | A primary cutaneous lesion in a 5-year-old boy who had recently received chemotherapy for acute lymphocytic leukemia was found to be caused by a dematiaceous fungus, Drechslera spicifera. The lesion was an erythematous macule that rapidly developed necrotic ulcerations. The fungus, which is commonly found in soil and a... | 559,473 | [
-0.03294387,
-0.6467883,
0.1078191,
-0.25867,
0.3525448,
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0.1150047,
0.07635063,
0.1887054,
0.03226014,
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0.094826,
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-0.06763972,
-0.03633628,
0.003326532,
0.4653514,
0.2704228,
-0.2202356,
... |
Studies of the aetiology of neonatal hepatitis and biliary atresia. | Aetiological factors were sought prospectively in 55 babies with extrahepatic biliary atresia, in 105 with neonatal hepatitis, and in 11 with intrahepatic biliary atresia, seen as a result of nearly complete ascertainment of these conditions in the State of Victoria between 1963 and 1974. In neonatal hepatitis infectiv... | 559,475 | [
0.1090149,
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0.1599212,
0.1813234,
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0.05560107,
0.3191898,
0.1681184,
0.1880593,
0.0406145,
0.1622735,
0.03608099,
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0.02856401,
0.1117637,
-0.09629678,
0.3044863,
0.2193247,
-0.06037991,
0.... |
Physarum polycephalum malate dehydrogenase: inhibitor analyses of the mitochondrial and supernatant isozymes. | The effects of naturally occurring metabolites were tested on the malate dehydrogenase (L-malate: NAD+oxidoreductase, EC 1.1.1.37) isozymes from the eucaryotic protist Physarum polycephalum. Several of the Krebs cycle intermediates were inhibitors for each isozyme indicating that a similar catalytic process was involve... | 559,534 | [
-0.3135785,
0.194361,
0.1225812,
0.1905697,
0.1150906,
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0.02110323,
0.1477236,
0.063762,
0.1502042,
0.2200687,
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0.1246756,
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0.2810332,
-0.2829046,
0.1654388,
-0.4475082,
0.2559338,
0.1759896,
0.2415471,
-0.03092753,
-0.12465... |
Sucrose density differences of Chlamydia psittaci 6BC in relation to its host. | Previous studies on Chlamydia psittaci 6BC propagated in different hosts have shown differences in cytotoxicity but no differences in the ultrastructure of the individual particles. It is shown here that the 6BC strain derived from yolk sac of infected chick embryo sedimented in sucrose gradients at lower densities tha... | 559,537 | [
0.0763282,
0.2126613,
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0.01013724,
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0.04315139,
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0.0219998,
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-0.207179,
0.2319896,
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-0.4647652,
-0.1387819,
0.003139258,
0.3611294,
0.4801549,
0.3465998,
0.007268733,
... |
Induction of persistent estrus by electrolytic lesions placed neonatally in the hypothalamus of the female rat. | Electrolytic lesions were placed in the hypothalamus of two-day-old female rats. Destruction of the mediobasal part of the preoptic area resulted in persistent vaginal estrus starting on the day of vaginal opening, while lesions placed laterally in the preoptic-anterior hypothalamic area did not interfere with normal c... | 559,574 | [
-0.1289559,
0.1723632,
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0.1279895,
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0.1078635,
0.04524924,
0.0889574,
0.1974478,
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0.04238373,
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-0.2657344,
0.1659573,
-0.03739141,
-0.4215902,
0.09156575,
0.3227372,
-0.003644675,
... |
Interactive effects of parity and pup stress on the maternal behavior of Rattus norvegicus. | Litters of primiparous and multiparous rat mothers received 0,2, or 5 min of cold stress for the 1st 5 days postpartum. Primiparae showed increasing maternal responsiveness over the treatment period. Multiparae were initially maternally responsive to moderate stress cues from pups, but habituated to them over days. Fro... | 559,607 | [
0.1261701,
0.216919,
0.1061826,
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0.3239979,
-0.02801293,
0.2119616,
0.1653561,
-0.2017888,
-0.1525761,
-0.01628502,
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-0.4745796,
0.3078774,
-0.2666864,
-0.01262038,
-0.06471758,
0.08803886,
0.2601544,
... |
Changes in fine structure of rat skeletal muscle related to cold acclimation. | Mitochondria became larger and some numerous in the internal red fibers of M. quadriceps femoris and neck muscle in cold-acclimated rats than in warm-acclimated ones, while they became less in number in spite of remarkable increase of size in the external white fibers of the former muscle. Mitochondrial cristae and sar... | 559,631 | [
-0.02958659,
0.2030118,
0.03276094,
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0.09228205,
0.1010799,
0.1425457,
0.2541851,
0.0436735,
0.02471945,
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-0.5619251,
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-0.4946344,
0.01012874,
0.2206036,
-0.3169948,
0.02535134,
0.09446145,
-0.0812431,
-... |
Practical mastitis control in the field. | Research has shown the effectiveness of teat dipping and medically treating all nonlactating cows to control mastitis. However, there is a problem of getting dairy-men to accept the program. Improved educational programs might be helpful. Some means of visual evaluation is essential to acceptance. Use of indirect tests... | 559,664 | [
-0.07668678,
0.3478106,
0.1006663,
-0.2689655,
-0.1600177,
-0.3629367,
0.1049948,
-0.2221754,
0.09479327,
-0.2083028,
0.07061365,
-0.06008063,
-0.2048019,
0.309728,
-0.5277245,
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-0.303552,
0.09764114,
-0.3125294,
-0.1672074,
-0.07146911,
0.1655249,
0.1539033,
... |
A mutation (gad) linked to mt and affecting asexual plasmodium formation in Physarum polycephalum. | Amoebae of the acellular slime mold Physarum polycephalum convert to plasmodia both asexually and sexually. Genetic analysis of a mutant that exhibits enhanced asexual plasmodium formation is reported. The mutant carries a single lesion (gad-11) located 12.3 map units from mt, a gene that controls mating specificity in... | 559,671 | [
-0.401197,
-0.1657514,
-0.2651812,
-0.1628234,
-0.3733538,
-0.2232098,
-0.1976551,
-0.2204973,
0.125841,
-0.03513973,
0.06660837,
0.7465592,
-0.1477111,
-0.07815902,
-0.6864709,
0.05538071,
-0.5282943,
0.326822,
0.06026456,
0.1697648,
0.330732,
0.3563093,
-0.07241434,
0... |
New prospects for a prolonged functional life-span of artificial hip joints by using the material combination polyethylene/aluminium oxide ceramin/metal. | Investigations over the years have shown that the mirror-finished Al2O3 ceramic is a much more suitable frictional counterpart to ultrahigh molecular weight (UHMW) polyethylene than metal. Despite the extremely gread hardness difference between polyethylene and Al2O3 ceramic, a considerable lower wear rate is obtained ... | 559,675 | [
-0.1437703,
0.5635496,
-0.01193146,
0.04130004,
-0.3096664,
0.06061123,
-0.04302591,
0.205079,
0.02675681,
0.1370826,
-0.09322279,
-0.223806,
0.4882222,
-0.04103664,
-0.360426,
-0.1724348,
0.04516676,
-0.01501964,
-0.1016576,
-0.02101639,
-0.0370946,
-0.2447293,
0.1462862... |
Burrows of wild and albino rats: effects of domestication, outdoor raising, age, experience, and maternal state. | Burrows dug by albino rats were compared with those of wild Norway rats in an outdoor pen and in observation chambers in the laboratory. Burrows, in terms of measurements, configurations, or sequential development, were indistinguishable in wild and domestic rats. Burrowing for both wild and domestic rats was unaffecte... | 559,696 | [
0.1814059,
0.2682889,
-0.1512973,
0.0660867,
0.3805922,
-0.4909414,
-0.147855,
-0.3400642,
-0.02472708,
-0.1358841,
0.0001571695,
0.2259545,
-0.1174336,
-0.03147895,
0.06643663,
-0.09115824,
-0.406732,
0.09601061,
0.01731329,
0.03822527,
-0.01403223,
0.5459773,
-0.0792038... |
A possible baculovirus in the insect-parasitic fungus, Strongwellsea magna. | Particles similar in appearance to the virions of the invertebrate baculoviruses have been found in large numbers in hyphae of the insect-parasitic fungus, Strongwellsea magna, growing in the fly, Fannia canicularis. The particles (100 X 390 nm) consisted to a densely staining core (50 X 340 nm) within a poorly stainin... | 559,724 | [
-0.1010677,
0.2734045,
-0.1535986,
0.1387892,
0.0352519,
-0.1469009,
-0.285075,
-0.07409342,
0.01542069,
0.1279899,
0.1295578,
-0.6454587,
0.02534344,
-0.02677359,
-0.6641307,
-0.1486249,
-0.3687389,
0.02739904,
0.6581725,
-0.1586791,
0.3918236,
0.6310752,
-0.157494,
0.... |
Aminophylline therapy in children: guidelines for dosage. | The oral dosage of aminophylline required for therapeutic "trough" serum theophylline levels was studied in 150 children, 16 months to 19 years old (mean 8.28 years). Dosage requirements tended to be higher for children under 10 years, but marked person-to-person variability in the relation of dose to serum level was s... | 559,735 | [
-0.4449552,
-0.08613645,
-0.405771,
-0.2680603,
0.1844391,
-0.2538741,
-0.34877,
-0.008525852,
0.08878711,
-0.2449262,
0.04726896,
0.1696625,
-0.1111785,
0.2811353,
-0.2816159,
0.02957968,
-0.4922706,
0.05242446,
-0.3961168,
0.1832035,
0.3256526,
0.2633043,
0.03817498,
... |
GLC-mass spectral analysis of psilocin and psilocybin. | With the combined technique of GLC-mass spectrometry, psilocin and psilocybin, two hallucinogenic indoles, were analyzed as their trimethylsilyl derivatives. The method was applied to these two components in an extract of Psilocybe cubensis (Earle) Sing. | 559,753 | [
-0.1484094,
0.2001461,
-0.2247495,
-0.08882928,
0.2524751,
-0.01966395,
-0.4133916,
-0.3988231,
0.08465782,
-0.1082158,
-0.06898648,
0.3754342,
-0.06174355,
0.1391196,
-0.1419261,
0.2982882,
-0.3944969,
0.2581744,
0.1444694,
0.1016031,
0.4112806,
0.01183093,
-0.01521335,
... |
Ionic currents through the membrane of the mammalian oocyte and their comparison with those in the tunicate and sea urchin. | 1. The action potential and the membrane current of the mouse oocyte were analysed by current-clamp and voltage-clamp techniques and they were compared with those of other animal oocytes. 2. The matured and unfertilized oocyte of the mouse in standard medium with 6 mM-K showed the resting potential of -23-1+/-2-9 mV. T... | 559,759 | [
-0.09187738,
-0.009722299,
-0.4940751,
-0.4457537,
0.02806774,
-0.03850336,
-0.02858858,
-0.003863317,
0.1594368,
0.007429557,
-0.08154995,
0.2429096,
0.2126494,
0.1004184,
-0.4208381,
-0.1020525,
-0.3319233,
0.2738302,
-0.2870005,
0.127489,
0.3705719,
0.06115053,
0.19725... |
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