title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Simple, rapid, and micro high-pressure liquid chromatographic determination of plasma griseofulvin levels. | A rapid high-pressure liquid chromatographic assay is described for the quantitative determination of griseofulvin in plasma. An aliquot (25--10 microliter) of plasma was deproteinized by a simple procedure involving the addition of 2.5 volumes of acetonitrile, vortex mixing for a few seconds, and centrifugation for 1 ... | 660,462 | [
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Solubilization of napthalene by sodium cholate and pattern of self-association of sodium cholate in 0.15 M sodium chloride. | Naphthalene solubility was determined in aqueous 0.15 M NaCl containing sodium cholate in the 0-0.05 M concentration range at 25 +/- 0.1 degrees. Sodium cholate tends to self-associate in aqueous solutions. Most often, the association pattern has been described in terms of a monomer-micellar model in which it is assume... | 660,475 | [
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Constituents of Cannabis sativa L. XIII: Stability of dosage form prepared by impregnating synthetic (--)-delta 9-trans-tetrahydrocannabinol on placebo Cannabis plant material. | Synthetic (--)-delta 9-trans-tetrahydrocannabinol impregnated on placebo Cannabis decomposed only 6.3% after being stored for 1 year at --18 degrees. Storage at 5 degrees and room temperature under various conditions led to severe decomposition. The amount of cannabinol observed when (--)-delta 9-trans-tetrahydrocannab... | 660,481 | [
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Assay of mercaptopurine in plasma using paired-ion high-performance liquid chromatography. | A sensitive, quantitative, and specific high-performance liquid chromatographic method for mercaptopurine in plasma is described. The analysis, in which mercaptopurine and the internal standard, 6-methylthio-2-hydroxypurine, are chromatographed as ion-pairs with heptane-sulfonic acid, employs a simple and rapid sample ... | 660,495 | [
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Perfluorooctyl bromide concentration in plasma and tissues of beagle dogs. | Plasma levels were determined frequently after single doses of perfluorooctyl bromide were administered to beagle dogs at doses of either 30.8 g/kg po or 3.9 g/kg intratracheally. The apparent first-order half-life during the terminal elimination phase was about 1 day after oral medication and about 7 days after intrat... | 660,500 | [
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Quantitative determination of prednisone and prednisolone in human plasma using GLC and chemical-ionization mass spectrometry. | A method for the quantitative determination of prednisolone and prednisone in human plasma utilizing GLC and chemical-ionization mass spectrometry is described. Corticosteroids are extracted from plasma into ether, and the extract is purified either by passing through a magnesium silicate column or by solvent partition... | 660,509 | [
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The effects of exercise and adrenaline infusion upon the blood levels of propranolol and antipyrine in the horse. | There are now several examples showing that experimentally induced changes in hepatic blood flow can have a marked effect upon the elimination of certain high clearance drugs. Changes in hepatic blood flow produced by exercise might therefore be expected to influence the clearance of these drugs. There was an increase ... | 660,540 | [
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Effects of methylglyoxal bis(ganylhydrazone) on trypanosomatid flagellates: inhibition of growth and nucleoside incorporation in Trypanosoma brucei. | Methyglyoxal bis (guanylhydrazone) (MGBG) at 0.5 mM had little effect in vitro on Blastocrithidia culicis, Crithidia oncopelti, and Leishmania spp., but completely inhibited growth of Trypanosoma brucei. Inhibition became irreversible after a 3-h exposure of T. brucei culture procyclics. Treated organisms remained moti... | 660,567 | [
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Analgesics and narcotic antagonists in the benzomorphan and 8-oxamorphinan series. 5. | 3-Methoxy-8-oxamorphinans 9 have been prepared from the corresponding 5-allyl-9alpha-hydroxy-2'-methoxy-2-methyl-6,7-benzomorphans 7. The former compounds were transformed to the 3-hydroxy-8-oxamorphinans 6, a class of potent analgesics and analgesic-antagonists. In ring C of the morphinan nucleus substitution of 8-CH2... | 660,584 | [
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3-Aryl- and 3-hydroxy-3-aryloctahydropyrido[2,1-c][1,4]oxazines. Synthesis, stereochemistry, and central nervous system pharmacological actions. | A series of substituted 3-aryl- and hydroxy-3-aryloctahydropyrido[2,1-c][1,4]oxazines has been synthesized for purposes of investigating potentially useful CNS pharmacological actions of this novel heterocyclic system. The preferred conformation of the bicyclic system of the parent compounds, 1 and 2, has been shown to... | 660,590 | [
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Benzomorphans. Structure of a position isomer. | May's benzomorphan synthesis leads not only to the alpha or cis isomer and the beta or trans isomer but also to a position isomer hereinafter called the gamma isomer. The structure and synthesis of this isomer are described. Biological activities of the alpha and gamma isomers are compared. | 660,593 | [
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Antiallergic 9-oxo-11-hydroxy-5H,9H-[2]benzopyrano[4,3-g][1]benzopyrans. | The synthesis and properties of the title compounds 1 are described. Several of these compounds, in addition to being potent inhibitors of the passive cutaneous anaphylaxis reaction of rats against egg albumin challenge, significantly block the effects of several mediators of anaphylaxis in isolated smooth muscle prepa... | 660,595 | [
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Membranous dysmenorrhea in the chimpanzee (Pan troglodytes). A report of four cases. | A macroscopic and histologic description of membranous dysmenorrhea in chimpanzees is given. The similarity of these cases to those in women make the chimpanzee an interesting model for studies on the presently unknown etiology of membranous dysmenorrhea. | 660,641 | [
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Ion transport by rabbit colon: II. Unidirectional sodium influx and the effects of amphotericin B and amiloride. | The unidirectional influx of Na from the mucosal solution into the epithelium of in vitro descending rabbit colon (JName) determined under short-circuit conditions, is comprised of two components: one represents entry of Na into transporting epithelial cells and is abolished by amiloride which also abolishes Na absorpt... | 660,645 | [
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Hyperglucagonemia and hepatic ketogenesis in burned swine. | A porcine burn model demonstrates hypoglycemia in spite of hyperglucagonemia. The ketone response to free fatty acids is defined for the normal and burned pig. Ketogenesis is augmented beyond that expected from free fatty acids during the postburn period. These metabolic changes may be related to the hyperglucagonemia ... | 660,669 | [
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Fracture of the distal radius with ulnar nerve palsy. | A patient with immediate palsy of the ulnar nerve secondary to a distal fracture of the radius and possibly a dislocation of the distal radio-ulnar joint (Galeazzi's fracture) is described. Surgery demonstrated a serious contusion of the nerve, scarring around the nerve, and thrombosis of the ulnar artery. Symptoms rap... | 660,675 | [
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Traumatic false aneurysm of the hand in hemophilia. | An unusual case of traumatic false aneurysm following a puncture wound in the hand of a hemophiliac, despite Factor VIII replacement, demonstrates the necessity for careful evaluation of such patients when there is profuse and continued bleeding. Following surgical repair of the false aneurysm and the ulnar proper digi... | 660,677 | [
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Oxygen consumption from fresh versus 21-day-old ACD whole blood. | The oxygen delivery capacity of fresh whole blood was compared with that of 21-day-old blood in an isolated, perfused canine hindlimb preparation. At the outset, 21-day-old blood was found to have depressed levels of 2,3 DPG and higher p50's relative to those of freshly procured blood, implying an increased oxygen affi... | 660,693 | [
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UV-induced mutation in bacteriophage T4. | Two late gene am mutants of bacteriophage T4 that can be induced to revert by UV were crossed to a temperature-sensitive ligase mutant. In the double mutants, UV-induced reversion was eliminated at a semirestrictive temperature. When the single am mutants were irradiated and then allowed a single passage in a permissiv... | 660,716 | [
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Bone marrow acid phosphatase in staging of prostatic cancer: how reliable is it? | To evaluate the reliability of bone marrow acid phosphatase in the staging of prostatic carcinoma we analyzed 50 bone marrow samples collected at random from the hematology service at this hospital. The samples were assayed for acid phosphatase content by a colorimetric method using sodium thymolphthalein monophosphate... | 660,763 | [
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The non-obstructive ectopic ureterocele. | We have seen 5 children with a non-obstructive ectopic ureterocele associated with an undilated upper pole collecting system. Thus the telltale signs of renal duplication found with obstruction of the upper pole were absent. Cystoscopy confirmed the diagnosis when retrograde injection of the ureterocele outlined a narr... | 660,768 | [
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Liquid protein diets and torsade de pointes. | Three women, aged 27, 33, and 35 years, experienced recurrent syncope five months after losing 36 to 41 kg using liquid protein diets. No abnormalities were noted during physical examination except in one who was hypothyroid. Serum potassium levels varied between 2.9 and 3.9 mEq/liter. The ECGs demonstrated prominent U... | 660,827 | [
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Further studies of periodic miniature response in squid giant axons. | Electric responses of extremely small amplitudes (1-30 muV peak-to-peak) repeating with more-or-less definite periodicity could be induced by a variety of chemical stimulants applied to squid giant axons either extracellularly or intracellularly. The chemical stimulants studied include allethrin, aminopyridines, N-brom... | 661,014 | [
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Signal monitor for audiometry. | Conventional volume unit (VU) and auditory monitors of signals generated by or fed through an audiometer do not allow monitoring of the signal after the attenuator or output selector. An amplifier-compressor circuit has been designed and constructed which allows auditory monitoring of the electrical signal at the trans... | 661,254 | [
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Effects of instructional set on the comfortable loudness range. | Ten normal-hearing young adult subjects measured their Comfortable Loudness Ranges (CLRs) using two instructional sets. The first instructional set (range tracking) was similar to the Bekesy Comfortable Loudness tracking method described by Jerger and Jerger (1974). The second instructional set (limit tracking) require... | 661,256 | [
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Assessment of parent-administered listening training for preschool children with articulation deficits. | Two studies concerning preschool misarticulating children are reported. The first study was concerned with direct effects of two varieties of parent-administered listening training. The second study focused on the influence of that same training on children's responses to sound-production training. Subjects were assign... | 661,262 | [
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Pulmonary gas exchange during venoarterial bypass with a membrane lung for acute respiratory failure. | In patients with fulminating pulmonary edema not responsive to conventional therapy, venoarterial membrane lung bypass can provide assistance if decreased systemic blood pressure prevents use of high-level positive end-expiratory pressure ventilation. In 10 patients with acute respiratory failure, partial venoarterial ... | 661,354 | [
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Protection of the ischemic myocardium. Ultrastructural, enzymatic, and functional assessment of the efficacy of various cardioplegic infusates. | The increasing use of cardioplegic protective infusates for reducing ischemic tissue injury requires that all infusates be carefully assessed for any protective or damaging properties. This study describes ultrastructural, enzymatic, and functional assessments of the efficacy of three infusates (Bretschneider, Kirsch, ... | 661,363 | [
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Fiberoptic bronchoscopy. Comparison of procedures used in the diagnosis of lung cancer. | We have compared the relative value of various techniques used in association with fiberoptic bronchoscopy for the diagnosis of lung cancer. We analyzed the results in 114 patients who underwent diagnostic fiberoptic bronchoscopy and in whom a definite histologic diagnosis of lung cancer was made. A comparison of the d... | 661,364 | [
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Left ventricular-coronary sinus fistula following repeated mitral valve replacements. | After mitral valve replacement, symptomatic deterioration and new murmurs characterstistic of atrioventricular valvular regurgitation are usually the result of periprosthetic leaks or prosthetic dysfunction with or without endocarditis. In the case which we are reporting, an iatrogenic fistula between the left ventricl... | 661,365 | [
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Comparative analysis of isolated aortic valve replacement with fascia lata and homograft valves. | Thirty-eight consecutive patients who underwent isolated replacement of the aortic valve with fascia lata in 1970 were compared with a similar series of patients undergoing homograft replacement of the aortic valve. These series were well matched in number, age sex of patients, symptomatology, valvular disease, electro... | 661,366 | [
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Repeat open intracardiac operation. Analysis of fifty operations. | Between December, 1972, and February, 1976, 50 open-heart operations were performed on 44 patients who had previously had open cardiotomies. Reasons for reoperation were failure of biological tissue valves (15 cases), failure of mechanical valves (12 cases), paraprosthetic reguritation (nine cases), recurrent or incomp... | 661,367 | [
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Continuous epicardial echocardiographic assessment of postoperative left ventricular function. | An ultrasound transducer which is sutured to the heart at operation and removal percutaneously has been developed and tested in 20 animals. The potential of this device to monitor cardiac function was measured by simultaneously recording 67 left ventricular angiograms and echograms over a wide range of hemodynamic func... | 661,369 | [
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Unusual echocardiographic findings in a patient with left atrial myxoma. | A 53-year-old patient is presented who had left atrial myxoma with unusual echocardiographic findings. The patient had been regarded for 10 years as having mitral stenosis. This error in diagnosis was due in part to misinterpretation of his echocardiograms. This report is presented to emphasize not only the unusual ech... | 661,386 | [
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Tension headache. | Headache is an extremely common symptom, and many headaches undoubtedly have a relationship to stressful situations. The clear definition, however, of a "tension headache" complex and its differentiation from migraine in some patients is difficult. The problems are in the identification of a specific headache pattern i... | 661,420 | [
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[Fibrous dysplasia of the facial bones (author's transl)]. | On the occasion of three cases of fibrous dysplasia (two of frontal sinus and the ethmoids and one of the upper jaw) the problem of fibrous dysplasia of the jaws is analysed. The clinical picture is characterized by a slow and gradual emergence of facial assymetric or exophathalmos. Histologically there is a variety of... | 661,466 | [
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[A rupture of the dorsal pharyngeal wall following a blunt neck trauma: 4th case in the world literature? (author's transl)]. | A report is given of a 22-year-old woman who suffered from an external non-penetrating injury to the ventral side of the neck resulting in a rupture of the dorsal pharyngeal wall. She was successfully treated with conservative therapy, i.e. intravenous fluids and conservative therapy, i.e. intravenous fluids and antibi... | 661,469 | [
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... |
Relationship between the plasma glucose level and glucose uptake in the conscious dog. | In the absence of a change in the pancreatic hormonal milieu, elevations in the normal fasting plasma glucose level have little effect on glucose clearance. In view of these data, and the previously established responsiveness of M to hormones, glucose clearance can be considered to represent a useful index of hormone a... | 661,564 | [
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0.127394... |
In vitro cytotoxicity of peritoneal macrophages activated with Mycobacterium smegmatis. | Incorporation of 3H-TdR into EL4 leukemic cells in vitro was inhibited by peritoneal exudate cells (PEC) harvested from syngeneic C57BL/6J mice given an intraperitoneal (i.p.) injection of 1x10(7) viable Mycobacterium smegmatis ATCC 607 (Smeg) 4 days before. This phenomenon was also observed in the following five syste... | 661,626 | [
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[Nucleotide makeup of the DNA of thermophilic bacteria of the genus Thermus]. | The nucleotide composition of DNA was determined in extreme thermophilic and obligate thermophilic nonsporeforming bacteria belonging to a new genus Thermus. The GC content (in mol%) in the DNA of exteme thermophilic bacteria varied from 65.3 to 70.8 per cent depending on the strain. The amount of GC (in mol% in the DN... | 661,633 | [
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Training health workers for primary care in a developing health service. | To provide primary health care in a thinly populated mountainous country with few doctors presents great difficulties. The Royal Government of Bhutan decided to base their primary medical care service on appropriately trained medical auxilliaries. The training programme is described, and the problems of assessing the f... | 661,662 | [
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Collusion of information on computerized patient management examinations. | In a computer presented examination the ratio of examinees to computer terminals is generally large. This implies that a computer presented test might span an entire day or several days with different groups of examinees taking the examination at different times. In such a situation, examinees who take the examination ... | 661,664 | [
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Coronavirus-like particles in Aboriginals and non-Aboriginals in Western Australia. | Pleomorphic virus-like particles which resemble coronaviruses in morphology were found in faecal specimens from Aboriginal and non-Aboriginal children in Western Australia. They were equally prevalent in those with or without symptoms of diarrhoea. A much greater proportion of Aboriginal than non-Aboriginal children we... | 661,689 | [
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Cardiological effects of nomifensine, a new antidepressant. | A cardiovascular study of a new antidepressant, nomifensine, revealed no significant cardiac effects in eight ambulant patients who received up to 200 mg of nomifensine per day for three weeks. In an electro-physiological study of cardiac conduction, nomifensine had significantly less effect on cardiac activity than am... | 661,706 | [
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[Reaction between synthetic fragment of histone F2al and the protamines iridine and salmine with DNA]. | The interaction of basic oligopeptides--F2aI histone, iridine and salmine protamines synthetic fragments with DNA has been studied by the methods of thermal denaturation, circular dichroism and equilibrium dialysis. All the peptides investigated are albe to stabilize the DNA helix and change its conformation. This abil... | 661,828 | [
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[Familial paroxysmal choreoathetosis. Clinical course, L-dopa-effect (author's transl)]. | The clinical course of two boys with familial paroxysmal choreoathetosis was traced. As far as the medical history could be retrieved, their family has been affected by this disease for three generations. Except for this disorder, the patients' development and psychophysical state are unremarkable. Both boys responded ... | 661,837 | [
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Role of cell shape in growth control. | Tissue culture plastic adhesivity was precisely varied by applying different concentrations of poly(2-hydroxyethyl methacrylate). The extent of cell spreading was thus accurately controlled so that cells cultured on these substrata could be held at any one of a graded series of quantitated cell shapes. Cell shape was f... | 661,946 | [
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Principles of the eradication or control of tsetse flies. | The success of attempts to control African trypanosomiasis afflicting both men and animals through the destruction of the tsetse vector depends on a realistic assessment of human and ecological factors in infested regions. The complete eradication of tsetse is at present possible only in limited areas, and elsewhere th... | 661,968 | [
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[Choledochal cysts. Clinico-radiological considerations and surgical technical notes]. | A successfully operated case of neonatal common bile duct cyst is described. Cystoduodenostomy was employed. Whether or not this condition is attributable to obstruction dysembryogenesis or aganglia is discussed. Assessment of the anatomopathological features leads to the establishment of three clinical types: cyst pro... | 662,107 | [
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[New method of simultaneous disobliteration of the visceral arteries and abdominal aorta]. | Simultaneous correction of abnormal blood flow is necessary in the presence of combined lesions of various branches of the abdominal aorta. The problem can be solved comparatively easily by using transaortic endoarteriectomy, a technique proposed here, which consists essentially of longitudinal incision of the aortic l... | 662,114 | [
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[Carcinoma fo the gallbladder. Experience and proposals]. | Poor survival observed in a series of 40 females and 44 males with cancer of the gallbladder treated over a period of about 16 years ar referred to in the formulation of three proposals designed to achieve better results: I) Earlier and more reliable diagnosis based on selective arteriography, echography and careful in... | 662,116 | [
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[Personal experience with vagotomy in the treatment of duodenal ulcer]. | Truncal vagotomy was employed in 120 cases of simple or complicated duodenal ulcer. Pyloroplasty was also performed in 98 cases, antroduodenostomy in 5, Billroth I or II in 12, and gastrojejunostomy in 5. No operative deaths were noted, even though the series included emergency situations and patients in poor condition... | 662,119 | [
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... |
[Surgical treatment of renvascular hypertension. Personal cases]. | Authors analyze a personal series of patients surgically treated for renal artery diseases (177 cases). Criteria of screening and diagnosis of stenosis are discussed and also are referred the clinical data. Authors describe their own personal reconstructive technique on renal arteries. Early and late results are widely... | 662,173 | [
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... |
The suspicious contraction stress test. | From a clinical service using the contraction stress test as an evaluator of fetal well-being, a 37-month review of the significance of the suspicious contraction stress test was performed. There were no antepartum losses in a group of 107 patients whose initial test was suspicious. Following each testing a number of p... | 662,222 | [
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0.02618523,
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In utero exposure to DES. Evaluation and followup of 199 women. | Among 199 women from 12 to 30 years of age who had been exposed to DES in utero, the colposcopic evaluation of the vagina and cervix was considered normal for only 13.6%. The incidence of colposcopically detected lesions was not related to the trimester of DES exposure, the patient's age, use of oral contraceptives, or... | 662,229 | [
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0.5390952,
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Pilocytic (juvenile) astrocytoma of the optic nerve. The influence of biopsy. | The biopsy and the decompression of a pilocytic (juvenile) astrocytoma of the optic nerve may caused increased mucoid formation and increased meningothelial reaction (meningioma formation) and therefore expansion of the tumour remnants. Experiences in the literature and our own clinical, histological and electrron micr... | 662,271 | [
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Surgical correction of far advanced otosclerosis. | The patient with far advanced otosclerosis (a nonmeasurable bone-air gap) may appear superficially to be suffering from profound or total sensorineural impairment. Only by a careful history and examination can a proper diagnosis be made. Stapedectomy has produced satisfactory results in 46 per cent of these cases in ou... | 662,339 | [
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Early developmental changes of the schistosomula of Schistosoma mansoni in vitro and in mouse lung. | Fresh (3 h) schistosomula of Schistosoma mansoni were obtained by the skin penetration method and injected intravenously into groups of mice either immediately or after 48 h incubation in tissue culture. Schistosomula were then recovered from the lungs 1 to 2 days after injection. The recovery results showed that the a... | 662,413 | [
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High performance liquid chromatography for the detection of homozygotes and heterozygotes of Niemann-Pick disease. | A method is developed for the detection of homozygotes and heterozygote carriers of Niemann-Pick disease type A by employing a high performance liquid chromatography (HPLC) technique for the measurement of sphingomyelin (SP) as well as for the assay of the enzyme sphingomyelinase (SPase) in skin fibroblasts and amnioti... | 662,470 | [
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Torsion of normal uterine adnexa in childhood: case report. | A case of torsion of a normal right ovary and tube in an 8-year-old child is presented. True infarction of the adnexa can be prevented only by considering this diagnosis early in the course of right lower quadrant pain. It is recommended that a routine exploration of the pelvis be carried out in any patient explored fo... | 662,481 | [
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Child-resistant locks in poison control. | Three child-resistant locks were incorporated into a medicine cabinet, an under-the-sink cabinet, and a vanity box. Three hundred 3- to 5-year-old children were tested against these locks. Only two were able to open the receptacles, whereas all 50 of a group of adults and teenagers similarly tested were able to open al... | 662,515 | [
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... |
Reinforcing effects of prerecorded words and delayed speech feedback on the verbal behavior of a neologistic schizophrenic. | The possibility of using prerecorded words and 2-sec. delayed speech feedback as reinforcement in the reconditioning of intelligible verbal responses in a chronic, neologistic schizophrenic patient was investigated. A test situation was devised which involved daily presentation of 100 stimulus word-picture cards to eli... | 662,530 | [
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Relation of dance skills to body cathexis and locus of control orientation. | 33 subjects provided measures on extent of dance training, dance performance, locus of control orientation, and three measures of body cathexis. Pearson product-moment correlations yielded significant, though modest, positive relations between three measures of body cathexis and performance, and between time dancing an... | 662,546 | [
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Creative thinking and interests of eleven- and twelve-year-olds. | Scores on What I Like To Do were not shown practical for predicting creative thinking in 100 11- and 12-year-olds from low-income backgrounds. Interests did account for a significant proportion of the variance (36%) in common with Torrance's total creative thinking score in the 50 girls. Suggestions for research are of... | 662,557 | [
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0.160... |
Cautionary note on the use of short state-anxiety measures. | The report noted that the use of high item-remainder coefficients as the sole criterion in the selection of items for short state-anxiety scales from full scales can lead to inaccurate interpretation of results. It was demonstrated that the use of a four-item state-anxiety scale from the State-Trait Anxiety Inventory A... | 662,566 | [
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0.052... |
Neuropsychological and MMPI correlates of patients' future employment characteristics. | Previous research has suggested that patients' neuropsychological test scores correlate not only with neurologic status but also with their success in coping with some of the demands of daily living. This study investigated the utility of such laboratory test scores in predicting several vocational variables. Patients ... | 662,567 | [
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[Why, when and how dietary fiber will be used in gastrointestinal disorders (author's transl)]. | This paper reviews the current status of knowledge with relation to the effects of dietary fiber on intestinal physiology and pathology. Vegetable dietary fiber is a physical complex acting principally in the colon. Fibers have water-holding, cation exchange and absorptive properties and important effects on bacterial ... | 662,644 | [
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[Leydig cell tumours of the testis. Two cases presenting opposing sexual features : gynaecomastia, precocious virilisation, and revealed by study in vitro of aromatisation activity]. | Two Leydig cell tumours presented with changes in sexual characteristics. The first patient was a child with precocious puberty whilst the second was that of an adult with recurrent gynaecomastia. Histochemical examination in vitro of tumour tissue from the second patient made it possible to explain the synthesis of oe... | 662,657 | [
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Properties of a double gradient model for retinotectal specificity. | The properties of a double gradient model for retinotectal specificity are discussed. The model utilizes only two complementary molecules, each located on both retina and tectum, to determine position along the dorsoventral axis. Two possible modes of interaction between these molecules are assumed. One of these allows... | 662,922 | [
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... |
The yale cervical orthosis: an evaluation of its effectiveness in restricting cervical motion in normal subjects and a comparison with other cervical orthoses. | The Yale cervical orthosis is a lightweight polyethylene foam Philadelphia collar with molded fiberglass extensions over the thorax. This orthosis was studied on 17 normal subjects in the extremes of the ranges of flexion, extension, rotation, and lateral bending using roentgenograms and axial photographs to assess how... | 662,928 | [
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0.317025,
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Event-related slow potential (ERSP) correlates of thyroid gland function level. | This study shows an association between thyroid gland function level and event-related slow brain potential (ERSP) parameters (peak amplitude and area under the curve), obtained during "classical" and "operant" reaction-time paradigms. A significant positive correlation between ERSP parameters and 24-hr I131 uptake and... | 663,052 | [
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0.029... |
The chest radiograph in legionnaires' disease. | The chest radiographs of 24 patients with documented Legionnaires' disease were evaluated. Twenty-two of the 24 patients had positive findings for the disease initially. There was unilateral involvement in 68% and the most common lung shadows were poorly marginated round opacities (46%), diffuse patchy (25%) and periph... | 663,140 | [
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Single dose oral cholecystography. | The routine use of single dose oral cholecystography is suggested for the examination of outpatients. A diagnosis is more quickly obtained for the great majority of patients and there is a lower incidence of side effects. An effective method of contrast administration and filming is discussed. The medical, personal, an... | 663,149 | [
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Extra-axial posterior fossa lesions simulating intra-axial lesions on computed tomography. | Differentiation of extra- from intra-axial posterior fossa lesions is sometimes not possible on computed tomography. Six cases are presented wherein the lesion appeared to be intra-axial on computed tomograms yet angiographically and surgically proved to be extra-axial. False localization on computed tomography occurs ... | 663,158 | [
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Congenital dilatation of the intrahepatic bile ducts (Caroli's disease). | Caroli's disease (congenital dilatation of the intrahepatic bile ducts) was diagnosed in an 11-year-old girl with the aid of intravenous cholangiography. Recurrent abdominal pain, fever, and intermittent obstructive jaundice are the most common symptoms and usually develop during childhood or young adulthood. Operative... | 663,169 | [
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Analysis of pattern of recurrence in non-seminomatous testicular tumor. | In non-seminomatous testicular tumor, 60% of failures are seen within the first three months after diagnosis. The most common site of metastasis is the lung. Occasionally, bone, liver and brain metastases are seen. In this series of 33 cases, the definitively treated Stage I patients are alive and well for an average o... | 663,177 | [
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Comparison of skin doses to large fields using tangential beams from cobalt-60 gamma rays and 4-MV x rays. | Excess radiation to the skin during external beam megavoltage radiation therapy has reportedly caused excessive erythema in patients treated with the Clinac 4 linear accelerator on sloping surfaces, but not for similar treatments with cobalt 60. Doses at the epidermal level were measured under geometries simulating slo... | 663,179 | [
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Ultrasonic enhancement of cancer radiotherapy. | Ultrasound treatment (1.5 W/cm2, 1.9 MHz, C.W.) for 15 minutes either before or after x irradiation reduced the TCD50 of sarcoma-180 by approximately 40% while similar ultrasound treatment for up to 30 minutes did not reduce the TCD50 of the C3HBA mammary adenocarcinoma. Water bath heating (44.5 degrees C for 15 minute... | 663,180 | [
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0.02718935,
... |
Tumor reoxygenation and postirradiation vascular changes. | Postirradiation reoxygenation kinetics of the Walker 256 carcinoma were examined and related to radiation-induced changes in tumor vascular functions. Changes in the hypoxic cell component of irradiated Walker tumors may occur by two mechanisms. Reoxygenation of previously hypoxic cells may be due to an increased rate ... | 663,181 | [
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The adult hip: an anatomic study. Part I: the bony landmarks. | A comprehensive anatomic, pathologic and radiographic study of the adult hip was undertaken to define bony landmarks which, when altered, are reliable indicators of disease. Methodology included radiography of cadaveric specimens and analysis of over 300 anteroposterior (AP) radiographs of "normal" adult hips. This inf... | 663,192 | [
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Spinal cord compression by extramedullary hematopoiesis in agnogenic myeloid metaplasia. | Extramedullary hematopoiesis presented as a diffuse mass causing almost complete obliteration of the spinal subarachnoid space in a patient with known agnogenic myeloid metaplasia. Pre- and post-radiation therapy films correlate well with significant clinical improvement in his neurological status. | 663,196 | [
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... |
Peridurography with metrizamide: animal and human studies. | Metrizamide (300 mg l/ml) was tested for spinal peridurography in conscious dogs and humans. Epidural metrizamide was non-irritating in volumes up to 12 ml. Larger volumes caused mild discomfort in two patients. Radiographic contrast was satisfactory, and there were no sequelae. Peridurography with metrizamide (300 mg ... | 663,198 | [
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0.2293... |
The effect of the urinary bladder in obstetrical sonography. | Observations of random obstetrical cases out of a large-volume practice are presented to demonstrate the often overlooked effects of filling the urinary bladder for obstetrical sonography. The effects, predominantly evident in the second trimester, include: perssure effects on the lower uterine segment, displacement of... | 663,205 | [
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0.2312856,
0.1872942,
0.04758034,
-... |
Lordosis induction in the rat by prostaglandin E2 systemically or intracranially in the absence of ovarian hormones. | Within 20 minutes of an intraperitoneal injection, PGE2 induced lordosis responding to manual stimulation in 6 of 9 rats that were ovariectomized-hysterectomized and hormonally untreated. Similarly, intracranial application of PGE2, through guide cannulae that were chronically-implanted in the basal hypothalamus, induc... | 663,284 | [
-0.07420041,
0.0949544,
-0.06727429,
-0.214827,
0.2349124,
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0.2996245,
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-0.03411144,
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0.1032276,
0.1760889,
-0.05090299,
... |
[Improvement of Cherenkov counting method (author's transl)]. | Cherenkov counting efficiency has been considerably improved by a specified measuring geometry. Radioactive sample and wavelength shifter are separately dispositioned, where a butyl-PBD has been employed as a wavelength shifter in the form of liquid and solid solutions. This technique can get rid of the shortcoming of ... | 663,306 | [
0.03139491,
0.01500027,
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0.04438123,
0.08929684,
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0.1499897,
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0.06453709,
0.2450272,
0.1076598,
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0.2488297,
0.05119299,
0.4755269,
0.4858013,
-0.1071707,
0.04770636,
0... |
[Non-specific abnormality (so called "hot spot") on 99mTc-phytate liver scintigraphy of patients associated with superior vena caval syndrome (author's transl)]. | We have recently observed two patients with superior vena caval syndrome who showed a unique abnormality, so called "Hot Spot", on the 99mTc-phytate liver scintigraphy. This phenomenon seems to be related to the collateral venous circulation. It is supposed that its manifestation depends on the degree of venous dilatat... | 663,317 | [
-0.04788213,
0.3121092,
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0.02595493,
0.01072018,
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0.005473844,
0.1320983,
0.1698666,
0.02774401,
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0.1392792,
0.3829148,
0.01855658,
0.1754448,
0.2408663,
-0.06858838,... |
[Computer analysis of the EEG as an aid in terminating diet therapy in phenylketonuria]. | In 6 patients with PKU, being on a low phenylalanine diet, the effect of reintroduction of phenylalanine on the E.E.G. was studied. The children, therefore, received daily loads of 100 or 150 mg phenylalanine/Kg bodyweight, equally divided over the meals. Computerized spectral analysis of the E.E.G's was performed duri... | 663,350 | [
-0.08448136,
0.2980708,
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0.04668293,
0.369157,
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0.006124379,
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0.4691341,
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0.4615649,
0.02544761,
0.1814071,
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... |
Erroneous classification of a pleural effusion. The role of a traumatic thoracentesis. | The separation of pleural effusions into exudates and transudates is based on the pleural fluid LDH and protein content compared to the simultaneous serum LDH and protein content. A patient in biventricular failure presented with a right pleural effusion that met the criteria of a transudate. After a traumatic thoracen... | 663,419 | [
-0.2528661,
0.1181825,
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0.2029755,
0.1284687,
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0.01799465,
0.05084446,
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-0.4124426,
-0.2486064,
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-0.56606,
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-0.04574087,
-0.1871712,... |
Evaluation of the distribution of air and blood in emphysema patients using radioisotopic tracers. | Continuous recording of the respiratory cycle with the simultaneous or sequential radionucleic exploration (gamma camera) of ventilation (133Xe) and perfusion (MAT-99) was performed to determine the V/Q index in regional areas (Polaroid photography, mini-computer, memory visualization system, Benson incremental tracer,... | 663,425 | [
-0.13007,
-0.06744699,
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0.3815192,
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0.04644352,
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0.4061081,
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0.00987278,
0.1289118,
0.5084149,
0.2581494,
0.4091674,
0.2836059,
0.04324465,
... |
Clinical aspects of cardio-respiratory homeostasis. | Starting from general assumptions on the clinical aspects of homeostasis and on the functional correlations lung-heart in physiological and pathological states, the difficulty to diagnose an individual pulmonary heart disease is stressed, as well as the necessity to differentiate it from the cases of coronary heart dis... | 663,538 | [
-0.06045178,
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0.04074034,
-0.1401235,
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0.06717414,
0.05306598,
0.03127748,
0.03858792,
0.1582245,
-0.... |
Plasma clot retraction assay with standard platelet count. | After classifying the phases of blood clot retraction within the mechanism of blood coagulation and the factors on which this phenomenon is depending, the authors briefly review the methods employed for its investigation. An improvement based on the determination of plasma clot retraction, performed in a plasma with a ... | 663,534 | [
-0.1690994,
0.164427,
-0.0739632,
-0.4276197,
-0.02900581,
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0.2615671,
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0.1288016,
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0.1196085,
0.0131489,
0.1037553,
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0.01142283,
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0.1997656,
0.2008058,
0.0834915,
0.1061089,
-0.0... |
Effects of beta-adrenergic receptor blockade on metabolic rate and mixed venous blood temperature during dynamic exercise. | Mixed venous blood temperature and energy exchange were measured in sixteen healthy male volunteers at rest and during bicycle exercise of 12 min duration performed before and after intravenous administration of propranolol. The rise in blood temperature induced by exercise was about 30% greater following propranolol. ... | 663,546 | [
-0.1093992,
0.003161262,
-0.4718712,
0.1593875,
0.30766,
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0.06069074,
0.1284003,
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-0.5715054,
-0.1944143,
-0.02023756,
0.3373951,
0.1254895,
0.3685169,
-0.1073317,... |
Heterogeneity of hereditary methaemoglobinaemia: a study of 4 Cuban families with NADH-Methaemoglobin reductase deficiency including a new variant (Santiago de Cuba variant). | NADH-methaemoglobin reductase deficiency has been found in 4 Cuban families; 3 subjects carried the mild form of the deficiency while in 2 sibs of the fourth family the deficiency was associated with neurological involvement. The parents in this family were consanguinous and the sibs were shown to be homozygous for a n... | 663,552 | [
-0.1973626,
-0.01558505,
0.246398,
-0.1057264,
-0.107444,
-0.2340686,
-0.1308947,
-0.4014255,
-0.2335483,
-0.2672837,
0.3346541,
0.3974848,
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0.06276285,
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-0.2002702,
0.2684006,
-0.1164977,
0.1159652,
0.2448931,
0.05882038,
0... |
Follow-up of patients operated on for axillary hyperhidrosis by subcutaneous curettage. | In 161 patients operated on for axillary hyperhidrosis by subcutaneous curettage (322 axillae), Lugol's test indicated re-operation in 24 patients (44 axillae). Recurrences were due to inferior surgical technique. Post-operative complications appeared in 18 cases out of 161 patients (322 operations). | 663,567 | [
0.3170352,
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0.05229459,
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0.2623812,
0.1895886,
-0.08687156,
... |
[Methodological problems on the preparation and realization of multicientric field studies on mouth and salivary gland neoplasms]. | The objectives of multicentric field trials are to provide a base for future revisions of the TNM system in order to ameliorate the existing classifications or to create new ones. The data are collected in a prospective and standardized manner and their evaluation is centralized. Therapy and follow-up in each case are ... | 663,573 | [
-0.211243,
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-0.004046874,
-0.06605009,
0.2571461,
0.4081857,
-0.1797874,
-0.063347... |
[Congenital chloride diarrhea]. | Two siblings aged 18 months and 3 1/2 years with congenital chloride diarrhea are presented. This disease was first described by Gamble et al. and Darrow in 1945 and has not been observed to date in Switzerland. So far, 43 cases have been reported, half of them from Finland. The disease appears to be caused by an inbor... | 663,592 | [
-0.1395263,
-0.2160429,
0.04648966,
-0.2341299,
0.2136826,
-0.2909025,
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0.3039395,
0.3688567,
-0.06747054,
0.197131,
-0.3128908,
-0.3407465,
-0.6504764,
-0.05263524,
-0.0520792,
-0.02148871,
0.5157782,
0.0007456403,
0.1474... |
[Behavior of gentamicin in the kidney parenchyma. Studies on rats during and after treatment with therapeutic doses]. | The injection in rats of 4 mg/kg gentamicin results in accumulation and continued presence of the antibiotic in the renal parenchyma compared with its rapid elimination from other tissues. With repeated injections at 24-hour intervals over a period of 3 weeks, gentamicin concentrations in the cortex reach 356 +/- 139 m... | 663,595 | [
0.1932272,
-0.03997693,
-0.1316248,
0.02681588,
0.2269295,
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0.03613254,
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0.08976547,
0.1790726,
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0.06830139,
-0.03111758,
0.2830869,
0.3936552,
0.2749865,
0.2759447,
... |
Human lateralization from head to foot: sex-related factors. | Sex differences in the pattern and maturation of lateral asymmetries of the human brain have been recently found by a number of investigators, suggesting that sex-related factors may differentially affect the two sides of the body. In this study, asymmetries in the size of the two feet were strongly related to sex and ... | 663,611 | [
-0.3073951,
0.1844624,
-0.08713303,
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0.09417956,
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0.01416512,
0.1654028,
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0.144895,
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0.06140502,
0.2082247,
-0.4627202,
-0.1615597,
-0.2479564,
0.0946212,
-0.2781114,... |
Loss of hippocampal theta rhythm results in spatial memory deficit in the rat. | Rats learned, using distal room cues, to run to a goal on an elevated, circular track starting from any position on the track. The goal was one of eight equidistant, recessed cups set around the track, the goal cup being distinguished from the others solely by its position in the room. After learning, electrolytic lesi... | 663,646 | [
-0.2512661,
0.4129785,
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-0.1683392,
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0.0527785,
0.1012017,
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0.0009041272,
-0.3646725,
-0.291148,
-0.06795266,
-0.1038644,
0.1883303,
... |
Brain edema: induction in cortical slices by polyunsaturated fatty acids. | The presence of polyunsaturated and saturated fatty acids in leukocytic membranes prompted study of their possible role in the induction of brain edema. Polyunsaturated fatty acids including sodium arachidonate, sodium linoleate, sodium linolenate, and docasahexaenoic acids induced edma in slices of rat brain cortex. T... | 663,662 | [
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0.05742506,
0.1004826,
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0.3426307,
-0.007610114,
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0.04449352,
0.1827873,
0.08480466,
-0.1851446,
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0.03000336,
-0.3698042,
0.08889996,
-0.04196705,
0.1650671,
0.2381083,
0.3707899,
-0.077744... |
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