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Reoperation after abdominal trauma.
A five year experience with 782 patients requiring laparotomy for trauma is reviewed. Specifically, the 70 patients requiring unplanned reexploration have been studied to delineate the indications for and implications of such repeat laparotomies. The major indications for such reoperation were intraabdominal abscess (4...
665,894
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Primary neoplasms of the small bowel.
The treatment of thirty-one malignant and eleven benign neoplasms of the small intestine is reported. The most common symptom was abdominal pain followed by vomiting, diarrhea, weight loss, constipation, and gastrointestinal bleeding. In four cases small bowel perforated. Intestinal obstruction occurred in 31 per cent ...
665,896
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Giant duodenal ulcer: a dangerous variant of a common illness.
Giant duodenal ulcers are large posterior penetrations of the duodenum which, when undiagnosed, have a high mortality. Radiographic and endoscopic diagnosis, although not always feasible, enables prompt appropriate management with improved results. Nonoperative treatment is dangerous. Preoperative diagnosis permits pla...
665,897
[ -0.1889659, -0.0477526, -0.03058532, -0.273896, 0.330559, -0.2523502, 0.09333133, 0.01123844, 0.269518, -0.07589765, 0.2785441, -0.2687032, 0.03683681, -0.2455838, -0.1316688, -0.05306503, -0.316863, 0.05440263, 0.1461232, -0.2505032, 0.02908781, 0.06252623, -0.0790785, ...
Carcinoma of the papilla of Vater. A review of fifty-seven cases.
Fifty-seven cases of carcinoma of the papilla of Vater are reviewed. Clinical and pathologic features as well as results of various surgical treatments are summarized. The Whipple operation may be the operation of choice for cancer of the papilla of Vater, offering a chance for cure and obviating further surgery.
665,898
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A technic for freezing an extremity in preparation for amputation.
Freezing of an extremity permits delay in amputation, and the time gained can be devoted to such intensive therapy as may be indicated. A safe, efficient, and convenient technic is described.
665,915
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Radial artery cannulation: influence of catheter size and material on arterial occlusion.
A randomized, prospective trial of four different cannulae used for percutaneous radial artery cannulation was carried out in one hundred and forty-eight patients undergoing cardiopulmonary bypass surgery. Arterial occlusion was assessed using a modified Allen's test and an ultrasonic flow monitor. The incidence of com...
665,977
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Foetal hypoxia--an anaesthetist's approach to classification and prevention.
Nearly one third of perinatal deaths are due to hypoxia occurring during pregnancy and labour. Many factors contribute to foetal hypoxia and in order to group these into orderly categories a classification of hypoxia, which is familiar to anaesthetists, has been applied to the maternal and foetal circulations. This the...
665,978
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An oxygen failure warning and patient protection system. The Howison Unit.
A device is described which sounds an alarm to warn of oxygen supply failure. A the same time the nitrous oxide flow is cut off, and a reservoir in the device provides a continuing oxygen flow to the patient for about a minute. This results in increased inspired oxygen levels temporarily, reducing the risk to the patie...
665,982
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Anaphylaxis to alcuronium.
Five cases of severe anaphylactic reactions to alcuronium are described. Investigation suggested that these are probably true anaphylaxis to the drug. The cases illustrate the value of intradermal testing in detecting the drug involved and the necessity of using colloidal solutions and adrenaline in the management of h...
665,988
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Clinical evaluation of etomidate as an induction agent.
A comparative study between Etomidate and Thiopentone was carried out on 100 healthy female patients scheduled for post-partum abdominal sterilization under epidural analgesia. Our results show Etomidate to be a safe and effective induction agent, comparable to Thiopentone in having a rapid onset of action and rapid re...
665,989
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Naloxone has no effect on nitrous oxide anesthesia.
It has been reported that naloxone antagonizes general anesthesia in rats when the tail clamp is used as a painful stimulus to assess anesthesia. The authors' hypothesis is that this antagonism is to the analgesic component of anesthesia only, and that anesthesia assessed by a non-painful stimulus would not be antagoni...
666,051
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Comparison of ketamine and pentobarbital anesthesia in the Mongolian gerbil.
The clinical course of pentobarbital and ketamine anesthesia are compared following a single injection of each and as anesthesia for carotid ligation in the Mongolian gerbil. Induction time to pinprick insensitivity was found to be the same for each agent; however, ketamine allowed earlier emergence and, moreover, obse...
666,083
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Nitrogen inhalation as a method of euthanasia in dogs.
Thirty-four dogs were euthanatized in a chamber flushed with pure nitrogen. Electroencephalograms and arterial blood pressure, recorded during euthanasia, showed the dogs to be unconscious in an average time of 40 s and to be dead in 204 s. The dogs displayed no detectable signs of pain before unconsciousness occurred....
666,097
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[Infantile brucellosis (author's transl)].
Some aspects concerning brucellosis are revised. This is a disease with a high incidental rate among the children's population in Salamanca and bordering provinces. The local prevailing epidemiologic conditions are reviewed, as well as the most outstanding clinical features, which are in children, according to the auth...
666,126
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[Infantile cushing's disease with paradoxical response to dexamethasona due to a probable periodic hormogenesis (author's transl)].
A case of Cushing's disease in a ten year old girl with bilateral diffuse hyperplasia of the adrenal cortex and postoperative enlargment of the sella turcica is presented. The administration of dexamethasone elicited a paradoxical response with a clear elevation of the already high excretion of 17-hydroxycorticoids. Th...
666,127
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Skin involvement in generalized amyloidosis. A study of clinically involved and uninvolved skin in 50 patients with primary and secondary amyloidosis.
A punch or excisional biopsy of the skin was done in 50 patients with generalized amyloidosis: In 46, clinically normal skin, usually the forearm, was biopsied and in four, only cutaneous lesions. Amyloid was seen in the skin of 21 of 38 patients with primary and multiple myeloma-associated amyloidosis. Sixteen of 34 b...
666,134
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Limitations of continuous ambulatory electrocardiogram monitoring for detecting coronary artery disease.
To assess the value of continuous ambulatory electrocardiogram (ECG) monitoring for detecting coronary artery disease in symptomatic patients, we evaluated 70 patients with chest pain and normal resting ECGs prospectively by calibrated ambulatory monitoring, graded treadmill exercise, and selective coronary cineangiogr...
666,154
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Septic bursitis in the prepatellar and olecranon bursae: an analysis of 25 cases.
Five cases of septic prepatellar and 20 cases of septic olecranon bursitis are reported. All were men, with a mean age of 47 years. Seventeen had a history of recent trauma to the affected limb or sustained pressure on knees or elbows, or both, required by certain occupations. Septic bursitis was not associated with se...
666,181
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Aneurysm formation on the small pancreatic arteries in assoication with coeliac axis compression.
The coeliac axis compression syndrome has been recognized for 12 years. More recently an association between this syndrome and the occurrence of aneurysms on the collateral circulation has been described. A review of the coeliac axis compression syndrome is presented and the management of associated aneurysms discussed...
666,233
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Metabolic response to hypertonic glucose administration in Reye syndrome.
Blood substrate and hormone concentration were determined in 16 children with Reye syndrome prior to and following administration of hypertonic glucose. Baseline concentrations of lactate, pyruvate, alanine, glutamine, glutamate, proline, hydroxyproline, lysine, and aspartate were elevated (p less than 0.01), whereas c...
666,261
[ -0.1036509, -0.09004024, -0.1160521, -0.1600926, 0.02529206, -0.3932374, 0.1992827, -0.0179452, -0.3486212, 0.5796463, -0.04784069, 0.001051046, -0.3049138, 0.08599386, -0.1334241, 0.1659054, -0.2347231, -0.05153561, -0.2767215, 0.05163287, 0.1695241, 0.1071855, 0.209232,...
Accumulation pharmacokinetics of tobramycin.
Tobramycin pharmacokinetics is usually described by a one-compartment model, but this model fails to account for both the incomplete urinary recovery and prolonged post-treatment persistence noted with this drug. We examined the multiple-dose behavior of tobramycin in 35 treated patients with stable renal function, usi...
666,293
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Fungal toxicity of phosfon D and its reversion by lipids.
The growth retardant Phosfon D inhibits the growth of some yeasts and human pathogenic filamentous fungi. The toxic effects of the compound on the dermatophyte Microsporum cookei were completely reversed by adding ergosterol and oleic acid to the medium. The significance of these findings is discussed.
666,296
[ -0.04657124, -0.1095411, 0.1275697, 0.07559955, 0.3657549, 0.07690294, -0.1687661, 0.07124218, 0.1385821, -0.231557, 0.09739721, 0.03492932, 0.05997383, 0.2751225, -0.5513384, 0.01739124, -0.258807, 0.1099685, 0.2462392, 0.2662165, 0.2243085, 0.3184044, -0.3503412, 0.07...
Salabrasion of tattoos. A correlation of the clinical and histological results.
Twenty-six tattoos were treated by salabrasion. The salt was left on the abraded surface from zero to 24 hours. The percentage of residual pigment varied from 50%, when the salt was removed immediately after salabrasion, to 5%, when the salt was left in place for over 12 hours. When the salt was left on for variable pe...
666,323
[ 0.05457123, 0.1050356, -0.2453017, -0.3099524, -0.1529056, -0.2010039, -0.1203018, -0.2645092, 0.3012691, 0.03028133, 0.3094312, -0.01058852, -0.1573798, -0.1788496, 0.4967213, -0.4316519, 0.1281824, -0.2059518, 0.1775408, -0.1146461, 0.01714619, 0.138641, -0.130577, -0...
Columnar epidermal necrosis. A special form of toxic epidermal reaction?
A bizzare erythematosquamous, partially verrucose, crustly or eroded eruption developed in a 6-year-old boy one week after his first measles vaccination. The eruption regressed completely after a two-year clinical course. Histologically, the epidermis showed unique columnar eosinophilic degeneration. There was a dense,...
666,329
[ -0.2403383, -0.285042, 0.04767454, -0.07464997, -0.1240489, -0.5629495, -0.1058616, 0.1446756, -0.2780144, 0.2435426, 0.06364318, 0.1891145, 0.1186594, -0.2825931, -0.4807383, -0.032072, 0.002552137, 0.1576676, 0.06345391, -0.1483018, 0.6198141, 0.3007592, 0.01745986, -...
Peripheral pulmonary artery stenosis.
A term infant, born by caesarean section for fetal distress, developed grunting and cyanosis by 15 minutes of age. Ventilation at low pressures was achieved without difficulty but did not improve blood gas levels, and he died at 26 hours. Necropsy examination showed large heart and small lungs; histologically the lungs...
666,361
[ -0.02783555, 0.01642253, -0.08459084, 0.05649841, 0.1514348, -0.01892556, -0.2417645, -0.2721235, -0.02024219, -0.1375307, 0.3085213, 0.1031056, -0.1108328, 0.1293839, 0.2153331, -0.1448921, -0.2709163, 0.02369382, 0.2757168, -0.0490423, -0.07181605, 0.1542082, -0.0301313...
Metabolism of trans-nonachlor and related chlordane components in rat and man.
The metabolic fate of trans-nonachlor and heptachlor in rats was studied in vivo and in vitro by using microsomal preparations of the liver. During in vivo studies the rate of excretion into urine and feces was monitored. The major metabolic products were collected from the feces and their chemical structures were dete...
666,363
[ -0.3962202, 0.2872997, -0.3029652, 0.001459391, 0.02606783, -0.3329076, -0.6314016, -0.0200646, -0.1213139, 0.1188679, 0.2269212, 0.1728782, 0.2941277, 0.2550873, -0.2181319, -0.2079109, -0.3277871, 0.1685001, 0.2775405, 0.1455716, -0.09073821, 0.5315059, -0.0786664, -0...
Esophagogastrectomy: data favoring end-to-side anastomosis.
Review of the literature since 1968 disclosed that the average mortality following esophagogastrectomy in 13 major institutions was 20%. Approximately half of the deaths were attributed to leaks from the esophagogastric anastomosis. Further analysis of the literature revealed that both the rate of anastomotic leakage a...
666,372
[ -0.2398759, -0.3947183, -0.4026333, -0.3711435, 0.07151639, 0.08779333, 0.1857654, -0.2741872, -0.01562148, 0.151834, 0.1717943, -0.1337558, 0.03860852, -0.1182265, -0.1722729, -0.2220345, -0.07493473, 0.1834838, 0.2629474, 0.09073211, 0.3645963, 0.3281042, 0.005111489, ...
Results of esophagocardioplasty with gastric patch in the treatment of esophageal achalasia.
Since 1968 esophagocardioplasty with gastric patch was employed in 57 patients as a primary operation for achalasia of the esophagus and eight patients with previous operations for achalasia. Satisfactory results were obtained in follow-up studies up to eight years. The results indicate that this procedure is successfu...
666,375
[ 0.0456343, -0.185499, -0.2842876, -0.1807611, 0.1670619, 0.05296458, -0.2205555, -0.1890252, 0.09413003, 0.2451021, 0.4360681, -0.06955279, 0.08791173, -0.1857365, -0.1589717, -0.005919498, -0.3610807, 0.002256019, -0.3735813, -0.04468687, 0.3882763, 0.1448636, 0.02513499...
Femoropopliteal vein grafts for claudication. Analysis of 100 consecutive cases.
One hundred consecutive femoropopliteal venous grafts in 85 patients with claudication were followed for five years. At this time, three limbs had been amputated, approximately one quarter of the patients had expired, and 70% of the grafts in surviving patients remained patent. It is concluded that this operation does ...
666,381
[ 0.008746933, 0.03253645, -0.34688, 0.01765289, -0.006976817, -0.1926913, -0.01529036, -0.1155201, -0.2435063, -0.2634542, 0.2008825, 0.07427061, -0.2142009, -0.07821818, -0.06108311, -0.289101, -0.02353683, 0.1499538, -0.1892209, 0.4561255, 0.1656722, 0.3299787, 0.1225058...
Effects of pulsatile assistance and nonpulsatile flow on subendocardial perfusion during cardiopulmonary bypass.
We compared the effects of pulsatile and nonpulsatile perfusion in 12 dogs on extracorporeal circulation. In beating empty and fibrillating hearts at 37 degrees and 28 degrees C, coronary blood flow was measured by flowmeter and microspheres at diastolic pressures ranging between 50 and 130 mm Hg. At fixed systemic flo...
666,423
[ -0.3531592, 0.3430968, -0.2324811, -0.08014084, -0.3299734, -0.4378935, 0.1526626, -0.1200996, -0.1070926, 0.113341, 0.2012905, 0.08243455, -0.1746843, -0.3545892, -0.04846329, -0.1499507, -0.1857078, 0.1254041, -0.1402676, 0.181773, 0.03920324, -0.2785367, 0.01309032, ...
Intraoperative pacemaker electrical testing.
To determine the clinical value of intraoperative pacemaker system electrical testing, the results of 200 consecutive pacemaker procedures (95 ventricular and 6 atrial primary implantations, 88 generator replacements, and 11 system revisions) were reviewed. The rationale and technique of testing maneuvers are described...
666,427
[ -0.1056163, 0.06264552, -0.3829202, -0.1917934, -0.06068026, -0.2416457, -0.165031, -0.04462534, 0.02974299, -0.2046169, 0.1991848, 0.1571429, 0.002848193, 0.01784735, -0.240726, -0.2889664, -0.5477114, -0.0663211, -0.08974254, -0.07036374, 0.2118241, 0.05080549, -0.01101...
Left axillary incision (minithoracotomy) for PDA division.
From 1955 to 1975, 417 patent ductus arteriosus (PDA) operations were performed at Sapporo Medical University. The last 118 operations (28.3%) were done by division through the left axillary incision without mortality. Forty patients were less than 2 years old and 14 were less than 1 year old. The ratio of girls to boy...
666,429
[ 0.01877449, -0.04068816, -0.3788025, -0.2441416, -0.1947441, -0.1308833, -0.3074518, -0.2127352, 0.2385513, 0.08994816, 0.1224618, -0.1813959, -0.1570266, -0.1673847, -0.2662137, -0.2046611, 0.01893401, 0.4419195, 0.3481165, -0.2344081, 0.5330569, -0.001533965, -0.1700249...
Streptococcus bovis bacteremia and underlying gastrointestinal disease.
Twenty-six adults with Streptococcus bovis endocarditis and ten with bacteremia alone were studied to determine possible portals of entry. Of 36 patients (17 with endocarditis, eight with bacteremia alone), 25 had gastrointestinal lesions or manipulation. In 22, the gastrointestinal tract appeared to be the source of S...
666,468
[ -0.3394827, 0.03432704, -0.2276119, -0.1730644, -0.1276487, -0.236327, -0.1796169, -0.0598065, 0.009901674, -0.1000595, 0.1066387, 0.08892365, -0.2475447, -0.4958086, 0.2559538, 0.2423081, -0.5081577, -0.2176558, 0.2892444, -0.2770395, 0.1104339, 0.2459831, 0.08107515, ...
[Quantifiable morphokinesis in members of the hypothalamo-adenohypophyseogonadal axis of hormonally castrated boars. 2. Studies on norgestrel treated boars].
Norgestrel treatment of boars differed from analogous chloromandinone acetate treatment in that no significant morphokinetic effect was recordable from all parts of the hypothalamic-adenohypophyseal-gonadal axis. The morphometric parameters as well as the histological pattern obtained of the anterior lobe of the pituit...
666,515
[ -0.1060208, 0.2921536, 0.252226, -0.03415504, 0.2075866, -0.3169762, -0.3647737, 0.0825053, -0.04288782, -0.06680961, 0.1383726, 0.08160979, 0.4028137, -0.1901248, -0.2501658, -0.0175171, -0.1139467, 0.527767, -0.0005093327, 0.2365514, 0.6341445, 0.01891773, 0.09038824, ...
[The fixation of the flail chest with tension band wires (author's transl)].
A new technique of internal fixation of the flail chest was tested successfully in sheep. After reduction a 0.8 mm wire is passed twice intramedullary across the fracture and twisted under tension with two loops on the external side of the rib. This wire neutralizes bending and rotational forces and produces axial inte...
666,548
[ -0.2065555, 0.4616584, 0.2066156, -0.4500811, -0.1356094, -0.1263768, -0.1661085, -0.1761802, 0.006584137, 0.0461346, 0.03382214, -0.2265137, -0.04145984, -0.1553654, -0.003709092, -0.2250028, -0.362856, 0.165291, -0.3361416, -0.03795514, 0.4474245, -0.04892268, -0.015431...
[The therapy for pyogenic coxitis and its stabilisation with the fixateur externe (tubular system) (author's transl)].
The treatment of the destructive, unstable state of infection on the hip often takes an unfavourable course, because alloarthroplastic techniques are ruled out on principle, while the hip arthrodesis itself creates biomechanical problems under the incomparably more favourable aseptic conditions. The protracted trimming...
666,550
[ -0.04734704, 0.2417505, 0.01735799, 0.5354276, -0.01862072, -0.5595562, -0.2227502, 0.2046095, 0.1093616, 0.05041463, -0.2378242, -0.2835778, 0.165612, -0.0964394, -0.1056943, -0.002421731, -0.4350297, 0.09053273, -0.263063, 0.01564933, 0.4357785, -0.2041281, -0.1872611, ...
Electromyographic feedback and physical therapy for neuromuscular retraining in hemiplegia.
Electromyographic feedback was compared with physical therapy for its relative effectiveness in training motor activity in patients with hemiplegia. A cross over design was used, so that each patient served as his own control. Strong reinforcement for attentional direction and for successful response to established cri...
666,557
[ -0.3489582, 0.3196854, -0.333615, -0.2087855, 0.02790584, -0.4828045, -0.1337014, -0.007205182, 0.05150205, -0.162635, -0.1509996, 0.106694, -0.232839, -0.395494, -0.005831867, 0.002489509, -0.6032645, 0.1868691, -0.7514822, -0.01605105, 0.2770373, -0.02844873, 0.09044151...
Serum testosterone and sexual activity and interest in men.
There is considerable interest in the relationship between testosterone and sexual behavior in men, but the few available data bearing on this issue are inconclusive. This study is an attempt to clarify the relationships among various components of sexuality and serum testosterone concentration through examination of t...
666,569
[ 0.008905833, 0.296307, -0.148901, -0.2340241, 0.03785935, -0.3059116, -0.2544659, 0.2134102, -0.2758872, -0.2213676, 0.2364654, -0.051893, -0.2636721, -0.04824647, -0.3694566, -0.1596682, -0.311211, -0.1492987, 0.1645215, 0.2314213, 0.2394795, 0.1025917, -0.02013541, -0...
Adult sexual orientation and attraction to underage persons.
A random sample of 175 males convicted of sexual assault against children was screened with reference to their adult sexual orientation and the sex of their victims. The sample divided fairly evenly into two groups based on whether they were sexually fixated exclusively on children or had regressed from peer relationsh...
666,571
[ -0.1188513, 0.3390201, -0.1112591, 0.1724274, 0.4541865, -0.1529956, -0.5321845, -0.005782118, -0.3016114, -0.0120682, 0.1833538, -0.04470941, -0.08102395, -0.1172819, -0.04146438, -0.09015114, -0.4832476, 0.2236403, -0.09371216, -0.2594472, 0.1589856, -0.02857867, -0.101...
Hemifacial spasm. A vascular cause.
A review of the literature as well as recent surgical observations indicate that hemifacial spasm may be caused by normal or pathological vascular structures that cross-compress the facial nerve. The critical area of compression is invariably found at the brain stem exit zone of the seventh cranial nerve. In this area ...
666,603
[ -0.09101877, -0.1393695, -0.2150051, -0.5528625, 0.1557522, -0.234771, 0.05905099, -0.1394358, 0.1674938, 0.07256056, -0.04166177, -0.2329314, -0.3174562, -0.1566298, -0.1981219, -0.007621766, -0.1844581, -0.04455477, -0.1218197, -0.2099443, 0.2126177, 0.3221701, 0.155043...
Subacute demyelinating polyneuropathy responding to corticosteroid treatment.
Ten patients with subacute demyelinating neuropathy responded satisfactorily to corticosteroid treatment. The most prominent features in these cases were (1) subacute progression of diffuse polyneuropathy over weeks and months, (2) high spinal fluid protein level, (3) marked nerve conduction abnormalities, and (4) high...
666,609
[ 0.03751347, -0.228069, 0.0858478, -0.37003, -0.1588888, -0.4454197, -0.2541245, 0.07805018, -0.09998801, -0.09651149, 0.06846953, -0.03919187, 0.2623691, 0.3633656, 0.07390939, -0.2341219, -0.02322298, -0.1458025, -0.1156022, 0.02398789, -0.08607052, 0.009748919, 0.13605,...
Hemifacial spasm due to aneurysmal compression of the facial nerve.
Hemifacial spasm developed in a woman as the only symptom of an aneurysm of the posterior inferior cerebellar artery. Using microdissecting techniques, the aneurysm was clipped and moved from its distorting position at the brain stem exit zone of the seventh nerve. After surgery, she experienced immediate relief of her...
666,617
[ -0.2755293, -0.08456802, -0.304332, -0.4121014, 0.1381176, -0.1759018, -0.2753326, -0.0785956, 0.293339, 0.1517265, -0.02601833, 0.02211817, -0.2744969, -0.5642136, -0.08433839, 0.1046859, -0.04039194, 0.05764815, -0.1296073, -0.1860653, 0.3117068, 0.05589889, 0.09571327,...
Effect of long-term wear of hard contact lenses on corneal sensitivity.
The effect of years of wear of hard contact lenses on corneal sensitivity has been evaluated. By testing 91 subjects who had worn lenses for up to 22 years and a control group of 42 people, it was found that corneal sensitivity diminished exponetially. However, in five subjects who had abandoned use of their lenses, re...
666,631
[ -0.01219925, -0.03762663, 0.05798474, 0.01591901, -0.04778351, -0.154438, -0.3456533, 0.008704056, 0.2492047, 0.009970427, 0.08466433, 0.1567079, 0.07157062, 0.04879668, -0.1812885, -0.2425203, -0.5420749, 0.0566554, -0.3211648, 0.1159071, -0.1706708, 0.07372808, 0.152331...
Pediatric intraocular knife.
An intraocular knife was developed that is of fine sharpness and small size to permit easy use in the eyes of young children.
666,636
[ -0.2053382, 0.05427248, -0.3069114, -0.05197382, 0.02236214, -0.2573857, -0.4218026, 0.2401872, 0.2366472, -0.1127979, 0.4600687, 0.07763904, -0.06153412, -0.177413, -0.06727424, -0.1087097, -0.2644246, 0.2376873, 0.1293017, -0.2078388, 0.3170056, -0.1732027, -0.1017821, ...
Indications for radical neck dissection following radiation therapy.
The recent trend has been away from elective neck dissection in the management of patients with cancer of the head and neck. In addition, improved techniques of radiation therapy have demonstrated their capacity to eliminate and sterilize occult and even frank neck metastases. An unselected series of 409 radical neck d...
666,640
[ -0.1935883, 0.07797385, -0.3220191, -0.3057321, -0.2170454, -0.5423809, -0.01529755, -0.07980983, 0.1917883, 0.1283073, 0.1279955, 0.04471807, 0.04686938, -0.2604109, -0.2062953, -0.1467331, 0.09138034, -0.1658614, 0.1712302, 0.1159296, 0.2752165, 0.1970323, -0.06066188, ...
Primary tumors of the external and middle ear. III. A clinicopathologic study of embryonal rhabdomyosarcoma.
Embryonal rhabdomyosarcoma of the middle ear-mastoid is a highly lethal neoplasm of childhood in most cases, which clinically simulates a chronic infection. Extensive hemorrhage and necrosis in the biopsy specimen may obscure and often delay the diagnosis. Two of the six embryonal rhabdomyosarcomas in this study showed...
666,648
[ -0.2615066, 0.008729132, -0.3962417, -0.3282289, -0.1210211, -0.2912072, -0.2829373, 0.06338543, 0.01529892, 0.1229342, 0.1614525, 0.6122239, -0.3212157, 0.01346753, -0.163107, -0.04236975, 0.009895079, 0.1339841, -0.1812617, -0.01905165, 0.6335135, 0.1642816, -0.01941232...
Voluntary vacation attachments to rural general practitioners: experience with pre-clinical medical students.
In view of the continuing maldistribution of medical manpower away from rural practice, a voluntary vacation rural general practitioner attachment scheme was established for pre-clinical students. The responses of the students and preceptors to these attachments are discussed.
666,667
[ -0.1323803, -0.05154661, -0.2173659, 0.2495925, 0.3297464, -0.2261157, -0.1149056, -0.1895517, -0.0147228, 0.2575598, -0.03127243, 0.4026246, -0.1756949, -0.001500851, -0.5405385, -0.1567064, -0.5798612, 0.1771724, -0.2512837, -0.451515, -0.2900333, 0.2964127, 0.02726511,...
Concorde: ride quality and passenger reactions.
On four Concorde flights, recordings of environmental characteristics during flight were made and questionnaires were distributed to passengers to assess their reactions during and 24 h after their flight. The Concorde users were mostly traveling for business reasons. Most respondents were flying the Concorde for the f...
666,685
[ -0.1954272, 0.03077655, -0.08631085, 0.1738865, -0.09881268, -0.3840728, -0.3152931, -0.1760629, -0.0894189, -0.003095554, 0.05579713, -0.5667961, 0.2011518, 0.1339914, -0.07253247, -0.1192495, -0.1935394, 0.1018883, 0.1849471, 0.06928901, 0.1305226, 0.5373579, 0.00399045...
Affinity chromatography of bacterial lactate dehydrogenases.
The affinity system used was the immobilized oxamate derivative previously used to purify mammalian lactate dehydrogenases. The bacterial dehydrogenases specific for the L-stereoisomer of lactate behaved in the same way as the mammalian enzymes, binding strongly in the presence of NADH. The D-lactate-specific enzymes, ...
666,726
[ -0.1473315, 0.08243641, -0.04456284, 0.3943178, -0.1592043, -0.3132001, -0.2385361, -0.02472535, -0.185638, 0.09495907, 0.1679464, -0.07430755, -0.08181955, 0.07065508, -0.6934211, 0.04045103, -0.4679061, 0.1033426, -0.1358613, 0.1199745, 0.629427, 0.2959031, -0.4003823, ...
Properties of potato lectin and the nature of its glycoprotein linkages.
1. Potato lectin is a glycoprotein that contains about 47% (by weight) l-arabinose, 3% d-galactose and 11% hydroxyproline. It has a monomeric molecular weight of about 50000 and probably exists as a monomer-dimer system in aqueous solution, with the monomer predominating. It has a very high viscosity, which would indic...
666,730
[ 0.09659849, 0.06637315, -0.2672706, 0.1104104, 0.1049934, -0.2619043, 0.03969535, 0.03508009, 0.2344921, 0.2466821, -0.1313379, -0.02774288, 0.142785, -0.3093877, -0.1572388, 0.2539394, -0.3859873, 0.169425, -0.1087388, 0.1401293, 0.3335643, 0.09815162, -0.1106878, -0.2...
A comparative study of the proteoglycan of growth cartilage of normal and rachitic chicks.
1. Proteoglycan was isolated from growth cartilage of normal and rachitic chicks. 2. The proteoglycan from normal cartilage showed differences in chemical composition and physical properties from a comparable fraction isolated from bovine nasal cartilage. 3. The proteoglycan from rachitic-chick cartilage was of smaller...
666,731
[ -0.1795441, 0.02051776, -0.2900783, -0.1247082, -0.05779459, -0.3231517, -0.2024959, 0.1601125, 0.1542154, 0.1259329, -0.02072421, -0.1452262, -0.2912572, -0.4883779, 0.08690656, 0.3898994, -0.277225, 0.2837179, 0.1707672, 0.1151856, 0.2561687, 0.2876879, -0.1177066, -0...
The availability of inorganic sulphate in blood for sulphate conjugation of drugs in rat liver in vivo. (35S)Sulphate incorporation into harmol sulphate.
1. When Na235SO4 is injected intravenously in rats, it is immediately available for sulphate conjugation of the phenolic drug harmol (7-hydroxyl-1-methyl-9H-pyrido[3,4-b]indole) in the liver. This was established by following the time course of the biliary excretion of the sulphate conjugate of harmol, and the incorpor...
666,743
[ -0.120825, 0.2415417, -0.4456278, 0.01397401, -0.03334371, -0.3224556, -0.3417986, 0.1809328, -0.241784, -0.05910141, 0.1977671, 0.2909913, -0.07793643, 0.3106547, -0.4716156, 0.1046514, 0.005073538, 0.1475905, 0.2200826, 0.1170032, 0.2836964, 0.1954679, -0.04878928, -0...
Evidence that the coproporphyrinogen oxidase activity of rat liver is situated in the intermembrane space of mitochondria.
Preferential rupture of the outer membrane of mitochondria from rat liver releases coproporphyrinogen oxidase in parallel with components of the intermembrane space. Coproporphyrinogen III enters the mitochondrion through the freely-permeable outer membrane. Either protoporphyrinogen IX or protoporphyrin IX must then c...
666,752
[ -0.3697918, -0.1351831, -0.2873204, 0.1845403, -0.004272202, -0.1808733, -0.07142586, -0.1335471, 0.1450541, 0.05857218, 0.04497963, -0.2912203, 0.05087491, 0.01688762, -0.56462, 0.04694382, -0.4533048, -0.05109784, -0.160389, -0.06901499, 0.08508173, 0.123753, 0.1839608,...
A subgroup of ankylosing spondylitis associated with HLA-B7 in American blacks.
In a study of 34 American black patients with primary ankylosing spondylitis, 18 were found to be HLA-B27-negative. Of these, 10 possessed HLA-B7 (55.6%) compared to 23.7% of 59 B27-negative black controls (P less than 0.025, relative risk = 4). On comparing these 10 B7-positive patients (group I) with 16 B27-positive ...
666,873
[ -0.009152082, 0.2712823, 0.05820147, -0.1536565, 0.04185821, -0.2717409, -0.03349322, 0.03875925, -0.1391144, -0.3259415, 0.005265926, 0.0001124968, 0.1721999, -0.1016478, 0.1208527, -0.2954751, -0.1336098, 0.2706272, 0.1729681, -0.187741, 0.1992514, 0.3544231, -0.2530283...
Protective effects of clofibrate on isoproterenol-induced myocardial infarction in arteriosclerotic and non-arteriosclerotic rats.
Male and female, arteriosclerotic and non-arteriosclerotic rats were treated with the anti-lipemic agent, clofibrate, for 8 days and then subjected to an acute myocardial infarction by injecting them with two large doses of isoproterenol spaced 24 hours apart. The animals were killed at sequential time intervals during...
666,886
[ -0.01409789, 0.2820685, -0.2293995, -0.3170137, 0.1837682, -0.2245238, -0.2058455, -0.160567, 0.05451802, -0.2847353, 0.07057205, 0.05522768, 0.0103766, 0.2344938, -0.3357203, 0.07389733, -0.00527444, -0.152022, 0.2699268, 0.3946504, -0.1222844, -0.1173518, -0.2209525, ...
Effect of anaesthesia for delivery on the weight of infants during the first 5 days of life.
Two hundred and forty-one neonates who had been delivered vaginally were selected randomly. The control group consisted of infants delivered without anaesthesia. In the study groups either extradural (mepivacaine, lignocaine or bupivacaine), spinal or general anaesthesia was administered. Each of the six groups was div...
666,931
[ 0.08710039, 0.2004014, -0.1551941, -0.0287143, -0.01952441, -0.4091525, -0.1659823, -0.5696776, -0.1583658, -0.1011626, 0.2255471, 0.1588002, -0.03257812, 0.2388625, -0.1614648, -0.3747858, -0.3999181, 0.2495477, -0.1635311, -0.2062162, 0.423608, 0.4071163, 0.1799704, 0...
Heparin pharmacokinetics: increased requirements in pulmonary embolism.
Heparin disappearance after injection and plasma levels during continuous infusion were studied in normal subjects and patients with thrombophlebitis, pulmonary embolism, renal failure, and liver failure. Heparin removal in normal subjects after 75 u/kg was nearly linear with a clearance of 0.64 ml/min/kg, SD +/- 0.11....
666,973
[ -0.09102618, 0.06579383, -0.3905703, -0.04975833, 0.4798066, -0.2884246, -0.09757423, 0.2378135, -0.4622207, -0.1362905, 0.3124029, 0.2791433, 0.01402821, 0.1541159, 0.0491514, -0.1116592, -0.1537589, 0.1236566, 0.1546677, -0.1153051, 0.3938614, 0.1607276, -0.03834466, ...
Erythrocyte populations in pyruvate kinase deficiency anaemia following splenectomy. I. Cell morphology.
Light and scanning electron microscopic examination of fresh erythrocytes from the blood of four patients splenectomized for severe pyruvate kinase (PK) deficiency haemolytic anaemia has revealed three morphologically different cell populations. Most striking in these patients was the presence of crenated red cells (30...
666,977
[ 0.1794689, -0.2564149, 0.1165106, -0.08414205, -0.1964279, -0.2433385, 0.3631894, 0.0950904, 0.1243028, 0.04034707, 0.06802809, 0.1712622, -0.3109512, 0.2952371, 0.04036755, -0.2318155, -0.5793283, -0.206339, 0.2575416, 0.1835884, 0.08087824, 0.2902406, 0.004908062, 0.1...
The estimation of whole-body zinc and Zn turnover in rheumatoid and osteoarthritis using 65Zn tracer.
1. A method of estimating whole-body zinc, and Zn balances using a two-compartment model in combination with whole-body counting of 65Zn, is described. The method is applied to patients with rheumatoid and osteoarthritis. 2. The results suggested that there was not a wide variation in whole-body Zn and Zn turnover in i...
666,994
[ -0.1297468, -0.1311892, -0.2982528, -0.2357152, -0.2156457, -0.1763629, 0.01442298, 0.2171489, -0.04344715, -0.09539665, -0.006725532, 0.06936616, -0.002562651, 0.2339564, -0.3187774, 0.05416949, -0.08793352, 0.3647343, -0.1529254, 0.1057559, -0.0061053, 0.2347595, 0.0816...
Nuclear magnetic relaxation by the manganese in aqueous suspensions of chloroplasts.
Proton and oxygen-17 NMR relaxation rate (T1-1 and T2-1) data are presented for aqueous suspensions of dark-adapted chloroplasts. It is concluded from the dependence of the proton relaxation rates (PRR) upon Mn concentration that T1-1 and T2-1 are determined largely by the loosely bound Mn present in the chloroplast me...
667,017
[ 0.04769273, -0.2614016, -0.479197, -0.1940357, -0.2323356, -0.2605703, 0.03951982, -0.2151902, 0.06596276, 0.08026911, -0.2380047, 0.2708283, -0.0707841, -0.006112554, -0.5110567, -0.3669537, -0.4742121, 0.1291544, -0.01316592, 0.3701361, 0.3224422, 0.416886, -0.01842962,...
Association of the major coat protein of fd bacteriophage with phospholipid vesicles.
The association of the major coat protein of fd bacteriophage with a phospholipid bilayer was investigated by analyzing the protein's susceptibility to proteolysis and its circular dichroism spectrum when incorporated into single-walled phospholipid vesicles. In the limits tested, this association appeared to be indepe...
667,034
[ -0.3183388, -0.02983678, -0.1395179, -0.07418812, 0.0203051, -0.3005551, -0.0138508, 0.220651, 0.2079229, 0.1596925, 0.08168272, 0.0279265, 0.05260661, -0.09894586, -0.2174386, -0.03315034, -0.3912455, 0.0222053, 0.02933971, 0.01410088, 0.1820185, 0.0252077, -0.02612888, ...
Protein methylation in animal cells. II. Inhibition of S-adenosyl-L-methionine:protein(arginine) N-methyltransferase by analogs of S-adenosyl-L-homocysteine.
1. Protein methylase I (S-adenosyl-L-methionine: protein (arginine) N-methyltransferase, EC 2.1.1.23) has recently been purified in our laboratory from Krebs II ascites cells (Casellas, P. and Jeanteur, P. (1978) Biochim. Biophys. Acta 519, 243--254). In order to probe its binding site for S-adenosyl-L-methionine, thre...
667,065
[ -0.05292838, -0.1165282, -0.1236148, -0.3783846, 0.1125426, 0.001076606, 0.01894538, 0.09011761, 0.2171674, -0.05560599, 0.07354103, 0.1225105, 0.1447182, 0.3892042, -0.6258153, 0.2195741, -0.5249227, -0.05816288, -0.2428781, 0.2810931, 0.202553, 0.2003057, -0.185045, 0...
Inhibition of pancreatic lipase by mixed micelles of diethyl p-nitrophenyl phosphate and bile salts.
Solubility and Sephadex filtration assays have shown that dissolved diethyl p-nitrophenyl phosphate can be included into bile salt micelles with a partition coefficient of 32 : 1. This inclusion is probably a prerequisite for the organophosphate to inhibit lipase. The essential role played by colipase confirms that the...
667,092
[ -0.1600134, 0.2143624, -0.05129864, 0.0336666, -0.04648973, -0.2011727, -0.2862552, -0.1731618, -0.08401555, 0.2441015, 0.05056418, -0.05800345, -0.06353492, 0.2245069, -0.5513668, 0.06229183, -0.4865597, 0.1339809, -0.2800392, 0.4609419, 0.1548399, -0.1044976, 0.2942146,...
Studies on the F-actin.tropomyosin.troponin complex. II. Partial reconstitution of thin filament by F-actin, tropomyosin and the tropomyosin binding component of troponin (TN-T).
It was found that thin filaments are reconstituted from F-actin, tropomyosin and the tropomyosin binding component of troponin (TN-T) in vitro according to a self-assembly mechanism. Although a gel structure is formed when the three proteins are mixed in the order F-actin, TN-T and tropomyosin, it is in a metastable s...
667,108
[ -0.2882133, -0.01220904, -0.3909004, -0.2284703, 0.08384894, -0.2433026, -0.1133357, 0.3240522, 0.1040071, -0.03263389, 0.003458598, 0.1190369, 0.01625825, 0.0927203, -0.4410861, 0.02105683, -0.3977355, 0.0311149, 0.006055542, 0.3830017, 0.3971093, 0.08461466, -0.1457561,...
Relationship between polyamine contents and protease activity in the rat submaxillary gland.
The effect of polyamines on the protease activity in the submaxillary gland of castrated rats has been investigated in vivo. The protease activity, which is increased by testosterone, is also increased to a lesser degree by the subcutaneous administration of spermidine. The administration of putrescine was less effecti...
667,123
[ 0.04373649, 0.1100906, 0.05426317, -0.1501755, -0.1927069, -0.1659278, -0.03152779, -0.113706, -0.1225125, 0.13514, 0.3100318, 0.2995776, 0.1482277, 0.2699252, -0.1945353, 0.6326272, -0.3032428, -0.0661934, -0.1635703, 0.276375, 0.5734519, -0.1078785, 0.009626018, 0.107...
Choice of an aqueous polymer two-phase system for cell partition.
Partition of human erythrocytes in aqueous two-phase polymer systems produced by Ficoll and different molecular weight fractions of dextran and polyethylene glycol and the influence of the ionic composition on the cells' partition in the systems was studied. It is found that the Ficoll-dextran-40 system is characterize...
667,135
[ 0.01087179, 0.1418488, -0.2337061, 0.1822766, 0.08046852, -0.2315979, -0.04471919, 0.1660449, -0.004853942, 0.4158269, 0.03034057, -0.1230757, -0.1944013, -0.02988634, -0.3859374, -0.3177193, -0.08949059, 0.2799161, -0.07007514, 0.1242398, 0.689222, 0.1970371, 0.01547843,...
Collagen synthesis by human glomerular cells in culture.
Collagen synthesis was studied in three subcultured human glomerular cell types, by radiolabeled incorporation of [14C]proline and [3H]lysine. The epithelioid circular glomerular cells secrete a collagen with a single size of chain (possibly type IV) with a high ratio of hydroxyproline to proline, hydroxylysine to lysi...
667,136
[ -0.2149233, 0.04665361, -0.4591891, -0.06683291, 0.1208399, -0.3144141, -0.03094105, 0.1300111, 0.1739327, 0.4245574, -0.004017198, 0.1682999, -0.249314, -0.1126321, -0.4533902, -0.00367893, -0.3510013, 0.239326, -0.2635309, -0.03323705, 0.2276082, 0.2348945, 0.01292861, ...
Change of the protein composition of the thyroid colloid during treatment with propylthiouracil and thyroxine: a microgel electrophoretic study of single rat thyroid follicles.
Prophylthiouracil and thyroxine were given daily to rats for 4 weeks. Samples of colloid were collected in vivo from the superficial thyroid follicles during this period and their protein composition was analysed by gel electrophoresis. It was observed that the aggregates of thyroglobulin, i.e., the 27-S thyroid iodopr...
667,141
[ 0.1108681, 0.1944367, -0.2891837, -0.3697165, 0.1895897, -0.2731047, 0.07034021, 0.006334945, 0.1499697, 0.1651625, 0.08947247, 0.1888783, 0.02969972, -0.09408003, 0.1175405, 0.2854766, -0.01943311, -0.09202071, 0.05799432, 0.3339411, 0.08805451, 0.1485696, 0.001137243, ...
[Theory of the hypochromic effect in DNA].
A method for theoretical studies of hypochromism of natural DNA is presented. The DNA hypochromism changed in structural transitions of the helix-coil type is examined using the method developed. It is shown on E. coli DNA that the main cause of the DNA hypochromism increase during transitions from coil to helix is the...
667,145
[ -0.3624675, -0.07272502, -0.08826537, 0.1449321, 0.2510903, 0.07321426, -0.3180454, -0.08057801, 0.3490272, 0.2299595, 0.04624061, 0.302234, -0.2128865, -0.190239, -0.5648717, -0.1333821, -0.4787779, 0.05624655, -0.3933205, -0.1739447, 0.3349072, -0.0262768, -0.03160506, ...
[Resolution of the fluorescence and absorption spectra of chlorophyll a in the cell into its components].
The total number, band widths, absorption and fluorescence peak positions of universal forms of chlorophyll a in vivo were identified by means of computer curve analysis, Stepanov's relation and low temperature derivative spectroscopy. The identified pigment forms are as follows: Chl669(661), Chl676(674), Chl686(680), ...
667,148
[ -0.06048018, -0.1620126, -0.4253902, -0.168152, 0.1991803, -0.118814, -0.191641, 0.07731636, 0.2003992, -0.05329726, 0.1700298, -0.1198592, 0.06489641, 0.0743082, -0.146522, -0.2371095, -0.7834783, 0.2188644, -0.1527228, 0.2929946, 0.2280473, 0.3672068, -0.1708471, 0.30...
[Modeling the process of excitatory transmission from the mechanical portion of the auditory system to the nerve endings of the auditory nerve].
Sharpening of frequency selectivity of the mechanical part of the hearing system due to the transformation of the signals in the receptor system is investigated. It is proposed that excitation of neuron endings is proportional to the amplitude of the current which was produced by the difference of microphonic potential...
667,157
[ 0.01635993, -0.316814, -0.1946104, 0.08442108, 0.1181942, -0.43026, -0.3388976, 0.199916, 0.02884828, 0.2393707, -0.06127974, -0.03489684, 0.08615602, 0.01083191, -0.2283626, -0.283854, -0.6156942, 0.2067206, -0.1479106, -0.1174484, 0.4887985, -0.07887571, 0.1828552, 0....
[Model of the light intensity analyzer].
The paper deals with coding the light intensity in visual analyzer. The single "neurons" of the proposed model have the properties of B-, D-neurons (primary detectors) [1] or the properties of so-called detectors of the light intensity [2]. Such "psychophysical" characteristics of the model as Stevens law, Weber fracti...
667,155
[ 0.04592304, -0.07570916, -0.1241099, 0.19965, 0.3556045, -0.4058953, -0.2511272, -0.07568514, 0.1400615, -0.07707947, 0.08586578, 0.07152992, 0.1474091, -0.1294764, -0.5101797, -0.2970777, -0.3345595, 0.2729185, 0.2277942, 0.4026174, 0.08237943, 0.08713517, -0.09260419, ...
[Relationship between the phase sensitivity of inferior colliculus neurons and the frequency of the acoustic signal].
With tone frequency (F) lower than the neuron characteristic frequency (F0), the neuron OFF-response is maximal at the signal end-phase (phi) of about 90 and 270 degrees and is minimal at about 0 and 180 degrees. On the contrary, with F less than F0 the OFF-response is maximal at phi-values of about 0 and 180 degrees a...
667,156
[ 0.03394995, -0.1457743, 0.01974221, 0.01896487, 0.03064381, -0.3926255, -0.5123511, 0.2006825, 0.2924525, 0.04980412, -0.01915186, -0.3123069, 0.1016408, -0.2086238, -0.4908282, -0.7672049, -0.644917, 0.3740039, -0.3356274, 0.1104418, 0.6277102, -0.03982881, -0.05354882, ...
RNA metabolism in M1 adrenergic neuroblastoma cells.
RNA metabolism of M1 adrenergic neuroblastoma cells was investigated in logarithmic proliferating, stationary and differentiated states. [3h] uridine labelling experiments showed that in the stationary phase (10 days of culture) the cells incorporated less radioactive precursors into RNA than in the logarithmic phase (...
667,167
[ -0.284095, 0.003137944, -0.5233328, -0.4012805, 0.322955, -0.4924127, -0.3410216, 0.05353125, 0.06999415, 0.06823436, -0.1283147, -0.05269041, -0.07325756, 0.3569314, -0.5693021, 0.006547363, -0.210163, 0.08467004, -0.2122789, 0.0443597, 0.5223616, -0.05555928, -0.1027834...
[Effect of redox properties of the medium on the thermoluminescence of the chloroplasts of higher plants].
The dependence of thermoluminescence characteristics of higher plants chloroplasts on the state of the electron transfer chain (ETC) was studied. The state of the ETC was changed with variation of the the redox state of the medium with different additions (mixture of ferri- and ferrocianide, DPIP, and DPIP in the prese...
667,163
[ -0.225519, -0.08566137, 0.09564961, 0.2502491, 0.09284606, -0.04716689, -0.1265003, -0.09160379, -0.01502567, 0.05285247, -0.09722266, 0.2613274, -0.02368754, -0.2567194, -0.558329, -0.2194443, -0.4633478, 0.01812328, -0.1743648, 0.4213755, 0.3598232, 0.3944502, 0.1063175...
Nitrogenase--hydrogenase interrelationships in Rhizobia.
A review is given of the properties of the hydrogenase present in Rhizobium bacteriods together with a discussion and evidence of the function of the enzyme in relationship to nitrogen fixation. The efficiency with which nodules fix nitrogen i.e. the amount of hydrogen evolved as a ratio of the total electron flow thro...
667,179
[ -0.2365989, -0.1897675, 0.1533627, 0.2400998, -0.2776216, -0.4270449, 0.119529, -0.1708028, -0.06319686, -0.006874096, 0.03896713, -0.09236971, -0.2022376, 0.01835127, -0.5030869, -0.5075603, -0.2878927, 0.221001, 0.2387189, -0.09653693, 0.01435447, 0.3073544, -0.05401032...
Membrane energization in relation with nitrogen fixation in Azotobacter vinelandii and Rhizobium leguminosarum bacteroids.
Nitrogen fixation in A. vinelandii and R. leguminosarum bacteroides shows identical characteristics with respect to the dependence on membrane energization, the sensitivity to uncouplers, the ATP/ADP-ratio, and the dependences on flavodoxinhydroquinone as electrondonor. Although we have been successful in preparing ins...
667,180
[ -0.245706, 0.04825462, 0.01303486, 0.03362641, 0.07742497, -0.3161584, -0.03552183, 0.09008549, 0.2171978, 0.04429065, 0.1872852, 0.1816615, -0.04179907, -0.008655069, -0.5482684, -0.2192007, -0.5755557, -0.1201318, 0.01906014, -0.08696467, 0.1978127, 0.01386133, -0.13227...
Behavioral analysis of chronic cocaine intoxication in the cat.
Modification of cocaine's stimulant and local anesthetic behavioral effects as a function of chronic treatment was evaluated in seven female cats. Video tape of behavior pre- and post-cocaine (iv) on days 1, 4, 7, 10, and 13 in seven cats, and in addition, on days 21, 28, and 35 for s subset of four cats, was rated for...
667,228
[ -0.1245385, 0.2527905, -0.1801089, -0.2624908, -0.01580558, -0.2361079, 0.02065668, -0.2239211, -0.01845533, -0.09582555, 0.09582894, 0.03681138, -0.2260169, 0.5501065, -0.3065195, 0.05605535, -0.3574989, 0.2126474, 0.04884394, 0.2271902, -0.2344739, 0.1618008, -0.0543887...
The impact of stress experience on heart rate and task performance in the presence of a novel stressor.
The impact of prior stress experience on heart rate and task performance in the presence of a novel stressor was studied. During a training phase 42 female students were required to solve arithmetical problems under conditions of either no stressor, delayed auditory feedback, or distraction. Subsequently in a testing p...
667,242
[ -0.4738021, -0.1013587, -0.3677977, 0.06202662, 0.07637113, -0.3886094, -0.0721171, -0.06057258, 0.08506067, 0.148638, 0.007000259, -0.1073093, -0.07563919, -0.4560349, -0.3231893, -0.04187218, -0.3219944, 0.1990116, -0.4812543, -0.1133071, 0.1182984, -0.1448104, -0.12873...
Reproducibility of plasma renin activity (PRA) profile in essential hypertension patients.
Whether the same patient with essential hypertension (EH) has the same PRA profile at different occasions, is still uncertain. The validity of the classification of these patients into low or normal renin hypertension depends upon the reproducibility of this profile. A nomogram based on PRA and 24 hr urine sodium in no...
667,286
[ -0.06540383, 0.201817, -0.3934313, -0.4376042, 0.1233347, -0.6094154, -0.2134565, -0.1181242, -0.1473727, -0.07419424, 0.1398068, 0.02027804, 0.1781773, 0.09819636, -0.06518155, 0.1005866, -0.31001, 0.4395376, 0.001339662, 0.07449631, -0.3185302, 0.1161776, 0.2714723, 0...
The pumping mechanism of the nematode esophagus.
The radial orientation of the myofilaments in the nematode esophagus raises interesting questions as to how such a structure can function as a pump. A physical model of the esophagus of Ascaris lumbricoides was developed and the membrane theory of shells applied in order to relate the observed dimensional changes to my...
667,292
[ -0.2912287, -0.211125, -0.1777699, -0.139223, 0.2186545, -0.2067769, 0.08994602, -0.03028299, 0.319282, 0.185933, 0.0494974, -0.1992914, 0.07349141, 0.1701311, -0.325396, 0.1760189, -0.3916495, -0.1478155, -0.4267229, 0.1433192, 0.4556604, -0.08339325, 0.1285135, 0.0301...
Shear deformation effects in enzyme catalysis. Metal ion effect in the shear inactivation of urease.
The mechanism of the inactivation of the enzyme urease produced by subjecting its dilute solutions to hydrodynamic shear stresses in the range 0.5-2.5 Pa has been determined. By studying the kinetics of urease-catalyzed urea hydrolysis during application of hydrodynamic shear under varying chemical environments, we dem...
667,301
[ -0.3305976, -0.1376412, -0.1995866, 0.1489264, 0.05514192, -0.2316922, -0.1540145, 0.1722077, 0.2952549, 0.09002323, 0.009570877, 0.02880752, -0.1648647, -0.03498244, -0.1857855, 0.1814415, -0.09636284, -0.2647205, -0.493214, 0.08506522, 0.2307595, 0.04980718, -0.1693577,...
Effect of ultrasound on a bilayer lipid membrane.
The effects of continuous wave ultrasound at a frequency of 1 MHz in the intensity range of 0-1.4 W/cm2 on an oxidized cholesterol bilayer lipid membrane (BLM) were observed. Ultrasound at 1.5 W/cm2 broke the membrane; in the range from 0.5 to 1.4 W/cm2, it accelerated the draining of the bulk lipid solution from the a...
667,305
[ 0.002098141, 0.08591808, -0.2647941, -0.1762862, -0.05971911, -0.4668349, -0.08394992, -0.02607513, 0.129844, 0.01212544, 0.08734646, -0.3862037, 0.1088066, -0.0638843, -0.2333118, -0.2315321, -0.5028198, -0.1708508, -0.3370385, -0.02192875, 0.5195205, -0.06767132, 0.0811...
Temperature dependence of the survival of human erythrocytes frozen slowly in various concentrations of glycerol.
One widely accepted explanation of injury from slow freezing is that damage results when the concentration of electrolyte reaches a critical level in partly frozen solutions during freezing. We have conducted experiments on human red cells to further test this hypothesis. Cells were suspended in phosphate-buffered sali...
667,309
[ -0.3513368, -0.1574671, -0.4523197, -0.2339667, -0.1054968, 0.1172933, 0.06691636, 0.03637698, 0.1412333, -0.2001938, 0.1479236, 0.1872293, -0.1178021, 0.1755543, -0.1720538, -0.5081584, 0.0008295589, -0.01645692, -0.02681501, 0.5306811, 0.13616, 0.1866619, 0.07748308, ...
Consecutive immobilized enzymatic reactions in continuous stirred tank reactor systems.
The performance characteristics of two-enzyme reaction in a continuous stirred tank reactor (CSTR) are analytical investigated in this work. A model is formulated to describe the substrate concentration variations by taking into account the external and internal diffusion resistances. It is found that the reaction syst...
667,310
[ -0.05422387, -0.1683643, 0.130447, -0.1097085, 0.05700295, -0.236946, -0.06012568, 0.09291217, 0.214406, 0.1601203, 0.25249, -0.04506888, -0.1165037, 0.1804795, -0.1992433, 0.1752321, -0.7837832, -0.2106205, -0.03906701, 0.0645286, 0.1987151, 0.1780266, -0.06386665, 0.1...
Thermoosmosis through charged membranes. Theoretical analysis of concentration dependence.
A theoretical equation for thermoosmosis through charged membranes in electrolyte solutions is derived from nonequilibrium thermodynamics. The theory shows that the volume flux through the membrane is proportional to the temperature difference across the membrane. The proportionality constant, i.e., the thermoosmotic c...
667,311
[ -0.2767041, -0.244184, -0.2969927, 0.1847634, 0.06957958, 0.03177497, -0.2132203, -0.01360092, 0.02346233, -0.05929717, -0.01744566, -0.1266594, -0.01107415, 0.2147153, -0.1775381, -0.1971207, -0.3561509, 0.1087449, -0.3403322, 0.01867398, 0.3998555, -0.05168797, -0.02864...
[Changes of various indicators of brain metabolism in excessive stimulation of the body and the effect of etimizol on these changes].
In case of an excessive irritation (a 3-hour electrical stimulation) of the organism there were observed marked changes in the brain metabolism in rats. These changes were expressed in the exhaustion of noradrenaline stores and disturbances of energy metabolism, leading to reduction of the creatinphosphate level. Preli...
667,324
[ -0.01186039, 0.1291694, 0.2280511, -0.07680883, -0.08768946, -0.4086036, -0.4240432, -0.1448546, -0.2734242, 0.006408719, -0.01066759, 0.1361597, 0.1634802, 0.3353809, -0.6860231, 0.0840616, -0.3795532, -0.1703867, 0.0551082, 0.2256786, -0.1039527, 0.2083017, 0.08979531, ...
[Genetics and human cancers: methods of study (author's transl)].
The role of hereditary factors in the etiology of cancer is difficult to prove. However, one may precise a hereditary relationship in those cancers which are either transmitted as a monofactorial trait, or secondary to a hereditary disease, or linked to a genetic marker. Most often, it is necessary to fall back on fami...
667,375
[ 0.03174407, -0.3772161, 0.01458244, 0.07948783, -0.08624873, -0.3813927, -0.2552941, 0.1471559, -0.05373164, 0.2355948, 0.1930324, 0.1533861, 0.2218933, -0.2020403, -0.5751328, -0.2095596, -0.04956261, 0.01104419, -0.02606941, 0.4082642, 0.4156176, 0.1775608, -0.09520888,...
[HLA system and malignant diseases (author's transl)].
Since ten years, there is an extensive search for association between antigens of the major histocompatibility system HLA and malignant diseases. Data show only weak associations with Hodgkin disease and acute lymphocyte leukemia. For studies of a variety of solid tumours the difference between patients and controls do...
667,376
[ 0.1010763, -0.5092504, 0.06088483, 0.09434493, -0.1059195, -0.5804219, -0.1769819, -0.003497378, 0.07601845, 0.1981936, 0.2796622, 0.01049179, 0.1681872, -0.1586037, -0.2572599, -0.4900686, -0.3448588, 0.1325394, -0.05866123, 0.02775339, 0.2656314, -0.04280208, -0.3568743...
Ecology and health.
Health is commonly conceived as having fixed and universal aims, while conditions interposed by environmental and cultural conditions are often ignored or at least shunted to one side. Rejecting this point of view, the author asserts that health in any society should be defined in terms of ecological reality--that is, ...
667,410
[ -0.08961712, -0.03450421, 0.1757203, 0.1416153, -0.04941949, -0.1485611, -0.1857488, 0.07629211, 0.2021548, -0.2734454, -0.02999863, -0.1071422, -0.2166163, 0.02591822, -0.3916394, -0.09621227, -0.4267442, 0.02581584, -0.2540894, -0.1066543, -0.3588483, 0.3524413, 0.03407...
On the conductance pathway traversed by strontium in mediating the asynchronous release of acetylcholine by motor nerve impulses.
A study was made to determine whether the Sr2+ dependent asynchronous release of acetylcholine by nerve impulses is mediated by the conventional Ca2+ conductance channel or, as has been suggested recently, through an alternative ion pathway. Experiments were performed on the frog neuromuscular junction by the use of st...
667,415
[ -0.108532, -0.08201152, -0.2889414, -0.5135971, -0.08307419, -0.3016709, -0.1046604, -0.03483608, -0.01495144, 0.0002676081, 0.06061463, 0.2145758, -0.0200076, -0.02121336, -0.6237784, -0.2470357, -0.4316081, -0.07136723, 0.2057076, 0.1985679, 0.4908249, 0.04744252, 0.207...
Effects of droperidol on activity of carotid body chemoreceptors in cat.
1 The effect of droperidol on the spontaneous activity of carotid body chemoreceptors and on their response to various stimuli was studied in 21 anaesthetized, paralyzed and artificially ventilated cats. Carotid body blood flow was controlled with a perfusion pump, and drugs were injected into the perfusion circuit. 2 ...
667,417
[ -0.4823584, -0.09740911, -0.01380747, 0.09126979, 0.1619702, -0.05907595, -0.4881023, -0.2962602, -0.2117176, 0.2194366, 0.284624, 0.3790696, -0.1729147, -0.077665, -0.1308219, 0.01716352, -0.7228139, 0.183935, -0.0459213, 0.1542615, 0.03575634, 0.1264042, 0.07139272, 0...
Vasodilatation by prostaglandin F2alpha in the canine tongue through a parasympathetic mechanism.
1 The vascular bed of the tongue in situ was perfused with blood through the lingual arteries at a constant pressure in anaesthetized dogs. All drugs except for SQ 14,225 were administered intra-arterially.2 Prostaglandin F(2alpha) (PGF(2alpha)) produced a dose-dependent increase in blood flow through the lingual arter...
667,501
[ -0.05260456, -0.4254256, -0.2209854, -0.4072039, 0.1065452, -0.3553644, 0.08861499, -0.2684481, -0.01232403, -0.1006227, 0.3755614, -0.0620881, 0.1896829, -0.713584, -0.3736959, -0.1109802, -0.3906803, 0.01942703, 0.07087669, -0.07089297, -0.1544463, 0.0751069, -0.0233552...
Classification of suicide attempters by cluster analysis.
Cluster analytic procedures for classification were carried out on a sample of 236 suicide attempters. Rating variables concerned previous suicidal behaviour, details of the recent attempt and its motivation, mental state, and demographic characteristics. Results suggested the existence of three groups of attempters. T...
667,507
[ -0.1857486, 0.4445892, 0.008940037, -0.1147519, 0.4950065, -0.3355867, -0.4705488, -0.3637559, -0.01671774, -0.1617586, 0.01370819, 0.08716672, -0.2967151, -0.07264627, -0.2702366, 0.3121508, -0.1407618, 0.2696647, 0.3427467, 0.06020437, 0.2266264, 0.11279, -0.03200778, ...
Results of Heller's operation for achalasia of the cardia.
A survey of 102 patients with achalasia of the cardia treated by cardiomyotomy is reported. The technique of operation was unchanged throughout and the patients were followed up for a maximum of 22 years. Only 6 patients (5.8 per cent) developed renewed symptoms of reflux and 7 patients (6.8 per cent) had peptic strict...
667,543
[ 0.07890314, -0.1117726, -0.4496763, -0.1658152, 0.06594844, -0.1213626, -0.3461708, 0.06747401, 0.2291835, 0.1268326, 0.45895, -0.09240502, 0.2088601, -0.6223222, -0.1210687, 0.04750266, -0.03925754, 0.2601885, -0.04560395, -0.2497202, 0.5189046, -0.1127796, -0.09122381, ...
Thyroglossal cysts in children.
Of 69 cases of midline cervical swelling in children, the correct diagnosis was made in only 38 (55 per cent). Fifty cases of thyroglossal cyst or abscess were treated and 38 per cent suffered recurrence. Apart from failures in diagnosis, the main reasons for preventable recurrence were delay in surgery, failure to res...
667,547
[ -0.158483, -0.05278904, -0.2003706, -0.3401367, -0.04751411, -0.4078324, -0.484419, -0.2981986, 0.03216822, 0.01943059, 0.3101845, -0.1149844, -0.1968738, -0.1560334, -0.1682772, -0.2178275, 0.04110701, -0.028191, -0.03126008, -0.0140901, 0.4112726, -0.02032856, -0.186616...
Multiple congenital aneurysms in childhood: report of a case.
This paper reports the case of a girl who, at the age of 7 years, presented with a saccular aneurysm of a brachial artery. Over the following 8 years a further 15 aneurysm appeared, involving limb and visceral arteries and the aorta. Some, but not all, of these aneurysms have been operated upon. Complications included ...
667,548
[ -0.1855677, -0.01644051, -0.3259366, -0.2085207, 0.2561074, -0.2040396, -0.2114504, -0.1802035, -0.146693, 0.321907, 0.3689063, 0.2561373, -0.2649079, -0.3118197, -0.2305003, -0.1989553, -0.4441096, 0.2395967, -0.05223437, -0.1931503, 0.07980566, 0.03374939, -0.2495587, ...
Proctocolectomy without ileostomy for ulcerative colitis.
An operation has been developed that permits total removal of all disease-prone mucosa in ulcerative colitis but avoids the need for a permanent ileostomy. The colon and upper half of the rectum are excised and the remaining inflamed mucosa is stripped from the rectal stump down to the dentate line of the anal canal. A...
667,572
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Frontal 'oculomotor' area in alert cat. II. Unit discharges associated with eye movements and neck muscle activity.
(1) Unit activity in front 'oculomotor' cortex was recorded extracellularly from sites where subsequent electrical stimulation, using threshold current (50 microamperes), could elicit both eye movements and simultaneous neck EMG acitivity. (2) Of 103 cells, 19% were related to either eye movements or neck EMG activity....
667,604
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The dorsal and medial raphe projections to the substantia nigra in the rat: electrophysiological, biochemical and behavioural observations.
Electrophysiological experiments have been performed in urethane anaesthetized rats to investigate the projections from the dorsal (DRN) and medial raphe nuclei (MRN) to the substantia nigra. The biochemical and behavioural effects following discrete electrolytic lesions in the dorsal and medial raphe have also been in...
667,623
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