title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Alpha-methyldopa and drug fever. A study of the metabolism of alpha-methyldopa in patients and normal subjects. | The metabolism of alpha-methyldopa was studied in 5 patients with febrile reactions to the drug, and compared with the metabolism in 5 patients without such reactions and in 4 normal subjects. A depression of the drug metabolism was found in drug fever patients, which may affect either the intestinal mucosal conjugatio... | 685,725 | [
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The pericranium flap operation. A new operation for the treatment of progressive infantile hydrocephalus. A preliminary report of 20 cases. | A new operation is described for the treatment of progressive infantile hydrocephalus. A pericranial flap with intact blood supply is introduced into the right lateral ventricle and fixed in place by suture to the dura or the skull. Twenty cases were subjected to the new operation with four deaths. The operation was su... | 685,741 | [
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Contribution to the surgical treatment of acute supratentorial subdural haematomas. | Acute traumatic subdural haematoma suspected of extending over an entire hemisphere must be treated with all speed. To obviate unnecessary skin incisions and subsequent craniectomies and craniotomies during the operation, we think it advantageous to plan a series of burrholes at set points in order to; a) begin to clea... | 685,742 | [
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Characterization of potential indoor sources of ozone. | Ozone emission factors were developed for domestic electrostatic air cleaners and photocopying machines. The air cleaners had emission rates from 0-546 microgram/min. These rates will ordinarily not produce air concentrations which are greater than 60 microgram/m3 (0.030 ppm) above background. The emission rate for pho... | 685,826 | [
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Enhancement of air filtration using electric fields. | Although polarized electrostatic air filters are efficient air filtrating devices, their main disadvantages are difficulty in collecting conductive particles or in operating at relative humidities above 70%. We describe here a new filter design that eliminates these problems. A nonconductive media, normally a glass fib... | 685,827 | [
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Effect of propranolol on fetal tachycardia in diabetic pregnancy. | Propranolol was administered during the last 20 days of pregnancy to a diabetic woman because of fetal tachycardia (heart rate approximately 200 beats/min). With a daily dose of 160 mg of propranolol, a fetal heart rat of 120 to 160 beats/min could be achieved. Blood concentration of propranolol was measured in the mot... | 685,844 | [
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Progressive transmural electrographic, myocardial potassium ion/sodium ion ratio and ultrastructural changes as a function of time after acute coronary occlusion. | The progressive transmural electrographic, biochemical and ultrastructural changes as a function of time after acute coronary occlusion were systematically assessed in eight dogs. Transmural plunge electrodes with poles 1 mm apart were placed in the ischemic and nonischemic zones, and coronary occlusion was maintained ... | 685,853 | [
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Potent reduction of basal acid output produced by meperidine. | Meperidine is a potent narcotic related chemically and pharmacologically to morphine and atropine. To examine its gastric antisecretory activity a study designed to test the effect of meperidine on basal acid secretion was carried out: 100 mg of meperidine given intramuscularly reduced basal acid output (BAO) by 66.3% ... | 685,937 | [
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Vibriocidal antibody titer rise after rectal or anal administration of Vibrio cholerae in dogs. | In many developing countries and ablution with surface water is a daily habit. This water is heavily contaminated with microbes, raising the possibility that and contamination may lead to immune responses. This hypothesis was experimentally tested in 21 dogs by anal or rectal application of Vibrio cholerae suspension V... | 685,952 | [
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An outbreak of histoplasmosis at an Arkansas courthouse with five cases of probable reinfection. | An outbreak of histoplasmosis occurred at a county courthouse in Arkansas in July, 1975. Fifty cases were identified by symptoms and positive complement fixation (CF) tests and 18 others by the clinical findings alone. Only three positive CF tests (greater than or equal to 1:8) were found in a control group of 55 unexp... | 685,975 | [
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Hospital treatment of congestive heart failure. Management according to hemodynamic profile. | Selection of therapy for subjects with acute congestive dardiac failure usually involves a choice among a diuretic, a vasodilator and an inotropic agent. Three principal questions are involved in the decision: (1) Is cardiac out normal or depressed? (2) Is blood pressure normal or depressed? (3) is regional myocardial ... | 685,990 | [
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Primary amenorrhea associated with hirsutism, acanthosis nigricans, dermoid cysts of the ovaries and a new type of insulin resistance. | We describe a 15 1/2 year old presenting with primary amenorrhea, hirsutism, acanthosis nigricans and insulin resistance. Ovarian vein catheterization studies revealed bilateral excess plasma testosterone and androstenedione secretion, and at surgery multiple dermoid cysts of both ovaries were found in association with... | 686,026 | [
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Hairy cell leukemia: diagnosis and management. | Long-term follow-up of 18 patients with hairy cell leukemia seen at a single institution is reported: diagnostic and therapeutic modalities are described. Although the clinical features of this disease are homogeneous, it is frequently misdiagnosed initially. Bone marrow biopsy was diagnostic in all 17 patients studied... | 686,039 | [
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Pasteurella multocida infectious arthritis. | Pasteurella multocida, a small gram-negative rod, is a domestic animal saprophyte that occasionally causes disease in humans. Infectious arthritis may develop from a superficial animal bite or scratch. Nine previous cases of infectious arthritis due to this organism have been documented in the literature, and a tenth c... | 686,043 | [
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Tissue concentrations of free amino acids in term human placentas. | Five human term placentas were analyzed for total free amino acid concentrations. Calculation of tissue fluid distribution via 14C-inulin space enabled an estimation of placental intracellular amino acid concentrations based upon cord and maternal plasma concentrations. Maximum and minimum estimates for amino acid conc... | 686,088 | [
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How does maternal smoking affect birth weight and maternal weight gain? Evidence from the Ontario Perinatal Mortality Study. | A large data set was used to examine the possibility that maternal smoking during pregnancy causes low birth weights by reducing maternal appetite, eating, and weight gain. As always, birth weight distributions shifted downward as maternal smoking level increased. Maternal weight gain distributions, on the other hand, ... | 686,089 | [
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Intermittent breathing before death in fetal lambs. | The presence of fetal breathing, even if episodic in character, may not indicate fetal well being. In a study of fetal lambs with long-term implantation of catheters and electrodes, five of six lambs which died before the onset of labor had terminal episodes of continuous breathing, preceded by 4 1/4 to 45 1/2 hours of... | 686,090 | [
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The relationship between fixation disparity and heterophoria. | Twenty-five asymptomatic subjects with normal binocular vision underwent determination of the magnitude and direction of their heterophoria and their fixation disparity. Fixation disparity was measured at a 2-m fixation distance with the phase-difference haploscope under conditions simulating those of casual seeing. Wh... | 686,118 | [
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Therapy of scleritis with cytotoxic agents. | Four patients with severe anterior scleritis that had not responded to conventional therapy were treated with cytotoxic immunosuppressive alkylating agents alone (one case) or in combination with prednisone (three cases). Two of the patients had Wegener's granulomatosis, one pyoderma gangrenosum, and one rheumatoid vas... | 686,129 | [
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Line copy presentation slides with Kodalith. | Line copy presentation slides with white letters on a blue background can be produced with a two-step process. The slides are more permanent than diazo slides, and the process is faster and less expensive. | 686,132 | [
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Corneal effects of high plus hydrogel lenses. | Five aphakic patients and five phakic patients were fitted with high plus Bausch & Lomb Soflenses. We evaluated corneal edema, staining, vertical striae, and corneal thickness before and after a 5-hr wearing period. The high plus lenses produced average corneal-thickness changes of 9.6% and 7.1% for the phakic and ... | 686,137 | [
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Relation between high energy phosphate and lethal injury in myocardial ischemia in the dog. | The relationship between progressive depletion of high energy phosphate and the onset of lethal cell injury in ischemic myocardium following coronary occlusion has been evaluated. Myocardial ischemia was induced by proximal occlusion of the circumflex coronary artery for 15, 30, 40, or 60 minutes. Cell injury in the se... | 686,146 | [
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Focal glomerular sclerosis in the fawn-hooded rat. | We have examined the nature of focal glomerular sclerosis (FGS) in fawn-hooded (FH) rats. The fawn-hooded rat develops pathologic features similar to those observed in steroid-resistant focal glomerular sclerosis, ie, by light microscopy some of the glomeruli appear normal but others show areas of solidification confin... | 686,152 | [
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Irreversible ischemic cell injury. Prevention by chlorpromazine of the aggregation of the intramembranous particles of rat liver plasma membranes. | Ischemic rat liver tissue has been shown previously to exhibit a markedly accelerated rate of phospholipid degradation, producing a loss of almost one half the total cellular phospholipid with 3 hours of ischemia. Pretreatment of the rats with chlorpromazine completely prevented the disturbed phospholipid metabolism at... | 686,154 | [
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Turnover of kidney beta-glucuronidase in normal and Chédiak-Higashi (beige) mice. | Kidney beta-glucuronidase turnover has been examined by specific antibody methods in normal C57BL/6J mice and in coisogenic C57BL/6J beige mice, an animal model for the human Chédiak-Higashi syndrome. No effect of the beige gene on the rate of glucuronidase synthesis was detected in either untreated or testosterone-tre... | 686,157 | [
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Protein turnover in man measured with 15N: comparison of end products and dose regimes. | Whole-body protein synthesis was measured with [15N]glycine in malnourished and recovered infants and in obese patients. Comparisons were made: 1) between results obtained with single (S) and repeated (R) oral dosage of tracer; and 2) between urea and ammonia as end products. In the infants S and R gave similar values ... | 686,164 | [
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Chylomicron composition during duodenal triglyceride and lecithin infusion. | In lymph fistula rats infused intraduodenally with trioleoylglycerol emulsions, the secretion of triglyceride was enhanced and that of total and esterified cholesterol in chylomicrons was strikingly reduced when lecithin was added at 4-5 times the biliary lecithin secretion rate. During continued triglyceride secretion... | 686,165 | [
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Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves. | Physiological and pharmacological studies of hormones, drugs, and neurotransmitters often generate families of sigmoidal dose-response curves. Optimally efficient data analysis should involve simultaneous description of all curves, rather than fitting each one individually. We have developed a general computerized meth... | 686,171 | [
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-0.156679,
0.4981855,
0.3916273,
0.02285991,
0.05757278,
-0... |
Regulation of cerebral blood flow in the ovine fetus. | The effects on fetal cerebral blood flow (Qc) of changes in the carotid arterial and sagittal sinus venous PO2, PCO2, and oxygen content were studied in the chronically catheterized ovine fetus in utero at 130-140 days of gestation. Forty-seven measurements of Qc were made in 20 fetuses with radioactive microspheres. I... | 686,183 | [
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0.0750239... |
Preferential distribution of inhbititory cardiac receptors in left ventricle of the dog. | The purpose of this study was to determine the relative magnitudes of the reflex effects mediated by sensory endings in the left ventricle activated by intracoronary injection of nicotine or veratridine into left anterior descending (LAD) or circumflex (Cx) coronary arteries in the dog. Injection of nicotine or veratri... | 686,186 | [
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0.3566445,
0.1781077,
-... |
Left and right ventricular dimensions during ventricular fibrillation in the dog. | Ventricular dimensions by surface echocardiography and intraventricular pressures were monitored in 27 dogs before and during ventricular fibrillation (VF) induced by coronary embolization (nine dogs), potassium infusion (nine dogs) and calcium infusion (nine dogs). Left ventricular diameter (LVD) fell by an average of... | 686,190 | [
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Ewing's sarcoma. A light- and electron-microscopic study of 21 cases. | Twenty-one cases of Ewing's sarcoma were analyzed by light- and electron-microscopy and the fine structure compared to that described in previous publications. In the predominant "primary" tumor cells, glycogen was abundant in 53% of cases, infrequent in 33%, and rare in 14%. In three cases, microtubules, in associatio... | 686,232 | [
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Extensive cutaneous burn complicated by severe necrotizing amebic enterocolitis. Pathogenic factors resulting in severe amebic disease. | A 59-yr-old Mexican-American man developed fatal necrotizing amebic enterocolitis following an extensive cutaneous thermal injury. Those factors in the severely burned patient which predispose to amebic disease are discussed. | 686,242 | [
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0.1855282,
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Paracoccidioidomycosis (South American blastomycosis): treatment with miconazole. | Six patients with multisystem paracoccidioidomycosis proven by serology and culture or smear were treated with relatively brief courses of intravenous miconazole. Two had relapsed following prior therapy; 6 had active pulmonary, 4 laryngeal, 2 oropharyngeal, 2 lymphoid, and 1 abdominal disease. Paracoccidioides brasili... | 686,247 | [
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0.07548725,
-0.... |
"Ghost" forms of Giardia lamblia cysts initially misdiagnosed as Isospora. | Because of their distinctive morphology the cysts of Giardia lamblia usually are not mistaken for cysts or eggs of other intestinal parasites. At a hospital laboratory in Kentucky a case of giardiasis was encountered in which the initial fecal examination revealed only degenerated cysts of Giardia which were mistaken f... | 686,251 | [
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0.1620068,
0.3666319,
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... |
A thirty year study of breast cancer in a consecutive series of private patients. Is axillary nodal study a valuable index in prognosis? | A consecutive series of 435 patients with breast cancer followed from six to thirty years is presented. Radical mastectomy was the surgical procedure of choice and our experience indicated that the degree of axillary nodal involvement is a most important guide in establishing prognosis in this disease. The majority of ... | 686,271 | [
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Heart disease in pregnancy. The anaesthetic management of a patient with prosthetic heart valves. | The management of pregnant woman with a double heart valve replacement is described. The aspects of particular relevance to the anaesthetist are discussed. | 686,312 | [
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0.2208868,
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Gaisböck's syndrome: its hematologic, biochemical and hormonal parameters. | The syndrome of plethora without splenomegaly, leukocytosis, or thrombocytosis was described by Gaisböck in 1905. It was reevaluated in 25 patients through the study of numerous hematologic and biochemical parameters. Statistically significant findings included mild obesity; elevation of blood pressure (especially dias... | 686,487 | [
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0.2195988,
0.1838532,
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-0.006394009,
-0.3216... |
Circulatory effect of respiratory maneuvers. | The circulatory effects of three kinds of respiratory maneuvers--maximum breathing, voluntary hyperventilation, and the Valsalva maneuver--on cerebral blood flow, brachial blood flow, heart rate, and systolic blood pressure were investigated by means of the on-line Doppler ultrasonic technique in 20 men. Arterial gas c... | 686,489 | [
-0.07953505,
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0.06955032,
0.03041251,
-0.0014... |
Achalasia secondary to carcinoma: manometric and clinical features. | The clinical and diagnostic features of a secondary type of achalasia of the esophagus are described in seven patients with various types of malignancies. Patients with secondary achalasia presented with dysphagia of short duration and marked weight loss; mean age was 64 years. Esophageal manometry showed features iden... | 686,541 | [
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0.03967134,
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... |
A behavioral treatment of alcoholic methadone patients. | Alcoholism is a frequent complication of methadone treatment and is one of the few behaviors found to correlate with methadone treatment failure. To eliminate drinking among severely alcoholic patients, we tested the efficacy of incorporating methadone into a behavioral contingency to reinforce disulfiram ingestion. Me... | 686,545 | [
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0.4241694,
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0.1303273,
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0.008932921,
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0.1259257,
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-0.03918... |
Vascularized hyoid interposition for subglottic and upper tracheal stenosis. | Chronic subglottic and upper tracheal stenosis can be treated successfully with lumenal augmentation using a vascularized hyoid-sternohyoid muscle interposition into the stenotic area. Successful decannulation was achieved in eight of nine patients. Follow-up periods varied from 6 months to 36 months. Concomitant laryn... | 686,592 | [
-0.3927321,
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0.3397416,
0.4609519,
0.03300265,
... |
[Sialic acid content of human thyroglobulins iodinated at different levels (author's transl)]. | Sialic acid and iodine content were measured on 53 thyroglobulins from normal and pathological tissues. Sialic acid is significantly decreased in isolated cold nodules, and highly reduced in hot nodules and toxic adenomas. In these pathological situations, sialic acid defect could interfere with the iodination of the m... | 686,652 | [
-0.1640194,
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0.1844022,
0.298548,
0.2568498,
0.2785457,
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0... |
Variation in blood pressure in a New Guinea population. | The contributions of age and anthropometric, biochemical and socio-economic variables to blood pressure variation in the population of Karkar Island, Papua New Guinea are examined. Blood pressure does not change with age in males; in females there is a decline from ages 21 to 40 and an increase (in systolic pressure) t... | 686,671 | [
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0.003694227,
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... |
Search for heterozygosis in quantitative characters. | A method is described of searching for heterozygotes in a quantitative character, based on the idea that heterozygotes have more variable children than homozygotes. The variability in a set of sibs is therefore partitioned into components from the mother and father, using a least squares technique; a large component in... | 686,679 | [
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0.0360968,
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0.0111123,
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... |
[Biological method of identifying antibiotic substances at an early screening stage]. | A biological method was used in addition to the chemical methods of identification in the screening programme of new antibiotics. The method consists of evaluation of the effect of the crude antibiotic preparations on microbial forms resistant to various antibiotics. The efficiency of the biological method is shown. It... | 686,689 | [
0.05421851,
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0.1948249,
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0.1111598,
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0.00... |
In vitro activity and beta-lactamase stability of BL-S786 compared with those of other cephalosporins. | In vitro activity of BL-S786, a new parenterally semisynthetic cephalosporin, was investigated against 570 bacterial isolates. BL-S786 inhibited most Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Salmonella. It inhibited some Enterobacter and indole-positive Proteus, but it was less active against the... | 686,701 | [
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0.2500103,
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0.393777,
0.018... |
Mode of action of a structurally novel beta-lactam. | CP-35,587 {6-[d-2-amino-2-(p-hydroxyphenyl)acetamido]-2,2-dimethyl-3- (5-tetrazolyl)-penam} is a member of a new family of beta-lactam antibacterial agents. Because the biospectrum of CP-35,587 has features similar to both penicillins and cephalosporins, experiments were carried out to explore its mode of action. CP-35... | 686,705 | [
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0.3547162,
0.2029483,
0.3816317,
0.1025896,
-0.... |
A diffuse pustular eruption associated with ulcerative colitis. | Two patients each with a two-year history of chronic ulcerative colitis developed, over a 24- to 48-hour period, painful pustules involving the skin and oral mucosa. The pustular eruption was associated with a severe exacerbation of the colitis. Culture of the lesions and of the blood failed to reveal an infectious cau... | 686,728 | [
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0.2235738,
0.1263594,
0.3005336,
0.292523,
0.1552314,
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Spindle cell lipoma. An unusual dermatologic presentation. | A 30-year-old woman had nontender subcutaneous mass over the left temple that histologically demonstrated a mixed pattern of mature lipocytes and spindle cells, many in a palisading and fascicular pattern, separated by fibrous trabeculations. No cellular atypia or increased mitotic activity was seen, and a predominance... | 686,729 | [
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0.230079,
-0.1741463,
... |
Renin and aldosterone response in human newborns to acute change in blood volume. | Increased activity of the renin/aldosterone system in the neonatal period is now well established in both animals and man but the control mechanisms are poorly understood. We have monitored the plasma renin activity (PRA) and plasma aldosterone concentration (PAldo) in 14 infants undergoing 21 exchange transfusions. PR... | 686,771 | [
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-0.5406215,
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0.3657657,
0.288867,
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... |
At what age do bronchodilator drugs work? | Using a modification of the forced oscillation technique we have measured respiratory resistance before and after nebulised salbutamol therapy in 32 wheezing children aged 7 months to 3 years 7 monts. 12 of the children were also studied in a total body plethysmograph. No child under 18 months of aged showed a greater ... | 686,789 | [
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0.03189431,
-0.5100435,
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0.194373,
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0.09944781,
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0.2946045,
0.1223672,
-0.1828021,
-0.08722702,
... |
Erythrocyte glucose-6-phosphate dehydrogenase in lichen planus. | Cotton et al [1] comparing glucose-6-phosphate dehydrogenase (G-6-PD) activity in biopsies from patients with lichen planus (LP) with that in normal skin suggested that LP might be associated with a congenital abnormality of the enzyme in the skin. Ryan et al. [7] were unable to confirm these results. It is known that ... | 686,815 | [
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-0.3217466,
-0.3578709,
-0.06177666,
0.07782593,
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-0.03169054,
0.04910308,
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-0.0758719,
0.1647703,
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0.3517836,
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-0.3068069,
0.05568245,
0.1421619,
0.2237043,
0.3800162,
0.4087409,
-0.2343... |
Decrease in neutrophils observed in vivo in psoriatics after PUVA therapy. | In 56 patients leucocyte and differential counts were done before and at weekly intervals during PUVA treatment of chronic recalcitrant psoriasis. A statistical significant (P less than 0.01) decrease in the percentage of neutrophils was observed during the first week of the PUVA therapy. This observation could be clos... | 686,817 | [
0.2590503,
0.008136025,
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0.2087288,
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0.009629003,
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0.08831912,
0.1765584,
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0.1811107,
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0.3280509,
-0.06378837,
0.3004473,
-0.04133... |
[Maturation and aging of elastic fibers (authors transl)]. | The non-sunexposed skin of 12 healthy individuals was investigated under the electron microscope and the fine structure of normal elastic fibers was compared by different methods in 3 groups of age: 1--10 years, 30--50 years, and 60 years. 1. The elastic fibers of human skin may be semiselectively stained with silver t... | 686,823 | [
0.1947439,
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0.3855879,
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0.09845081,
0.4120478,
0.314913,
-0.2991921,
0.0... |
[Oxygen consumption of the spontaneous and artificially induced skincycle at different times of day (author's transl)]. | In the "clean" rat skin purified from the panniculus carnosus the oxygen consumption of the spontaneous and artificially induced skincycle was measured at different times of day. The level of oxygen consumption correlated to diurnal and nocturnal periods. During the skincycle the oxygen consumption showed fluctuations.... | 686,827 | [
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0.4011021,
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0.06274112,
0.255862,
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... |
Metal sensitivity in patients with a hinge arthroplasty of the knee. | Fifty patients who had received a hinge arthroplasty of the knee were investigated for possible metal sensitivity. Patients were patch tested against all the metal constituents of the prosthesis. Positive patch tests were found in 32% of patients. Seventeen patients had either lossening or a persistent sterile discharg... | 686,871 | [
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Endorectal mucosal resection without proctectomy as an adjunct to abdominoperineal resection for nonmalignant conditions: clinical experience with five patients. | Five patients with chronic ulcerative colitis underwent endorectal excision of the rectal mucosa without removing the rectal muscle in combination with total colectomy and cutaneous ileostomy. This operative technique will cure the patient of the primary disease and obviates many of the usual unpleasant complications f... | 686,892 | [
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The Zollinger-Ellison syndrome--23 years later. | The effects of recent diagnostic and therapeutic advances were assessed in 65 patients with the Zollinger-Ellison syndrome (ZES). Twenty-seven patients seen between 1955 and 1970 were compared with 38 patients seen between 1971 and 1977. The earlier patients had a higher incidence of virulent ulcer disease (56% vs. 24%... | 686,901 | [
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0.255... |
Tension development and associated calcium influx of control and reserpine pretreated rabbit aortae in response to norepinephrine, isoproterenol and acetylcholine. | The influence of reserpine (3mg/kg) pretreatment on phasic and tonic components of the contractile responses of rabbit aortae to maximally effective concentrations of norepinephrine, acetylcholine, and isoproterenol and on agonists-induced movements of 45Ca during these responses were studied. Four hours after reserpin... | 686,906 | [
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Urinary methylhistamine as an index of histamine formation during histidine decarboxylase inhibition in the rat. | A new method is described for the evaluation in vivo of histidine decarboxylase inhibitors. Urinary methylhistamine excretion is approximately trebled in rats treated simultaneously with the histaminase inhibitor aminoguanidine and the monoamine oxidase inhibitor pargyline, thus providing a high base-line against which... | 686,917 | [
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Chemotherapy of acute leukemia: a comparison of vincristine, cytarabine, and prednisone alone and in combination with cyclophosphamide or daunorubicin. | Adults (274) with acute leukemia (AML) were randomly assigned to one of three treatment regimens: vincristine, prednisone, cytarabine--(1) 100 mg/sq m/day with cyclophosphamide (COAP); (2) 100 mg/sq m/day with daunorubicin (DOAP); and 200 mg/sq m/day (OAP). Cytarabine was infused continuously for five days. Patients en... | 686,922 | [
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An automated verbal medical history system. | Computer-based automated medical history acquisition systems have not been as widely utilized as originally anticipated. The high cost, limited accessibility and alien nature of the computer terminal equipment have all been cited as important factors in the limited acceptance. A system has been developed that makes it ... | 686,925 | [
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Prostatic abscesses involving anaerobic bacteria. | Anaerobic bacteria have seldom been reported in prostatic abscesses. The present study concerns four cases in which the exudate was cultured with optimal microbiological techniques. Our results showed a complex aerobic-anaerobic flora in each instance, with a total of 21 isolates, including seven aerobes and 14 anaerob... | 686,927 | [
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Red blood cell casts in acute interstitial nephritis. | A 45-year-old woman receiving hydralazine and hydrochlorothiazide therapy was found to have a reduced glomerular filtration rate, a positive antinuclear antibody reaction, and RBC casts in the urinary sediment. Glomeruli with normal morphology (light, immunofluorescence, electron microscopy) were found on renal biopsy;... | 686,935 | [
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... |
Treatment of ruptured interventricular septum with afterload reduction. | Two patients with a ruptured interventricular septum complicating acute myocardial infarction were treated with isosorbide dinitrate. The first patient recovered from cardiogenic shock after sublingual administration of 5 mg of isosorbide dinitrate every two hours and was successfully operated on. The second patient re... | 686,938 | [
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... |
[Cytopathology of bronchial tree secretions in bronchial asthma patients]. | The methods of clinical cytology were used for examination of 64 patients with bronchial asthma (42 men and 22 women). Six patients were found to have an atopic form of asthma, 58--the infectiousallergic form. The material for a cytological examination was obtained by bronchoscopy. Early in the exacerbation stage and i... | 686,987 | [
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[Morphologic features of erythrocytes in normal subjects and in anemia caused by lead poisoning (electron microscopic study)]. | The methods of scanning and transmission electron microscopy were used to study erythrocytes from normal subjects and those suffering from anemia of lead poisoning genesis. Erythrocytes from normal subjects were shown to have predominantly convex-concave and biconcave shapes. An insignificant portion of ageing erythroc... | 686,988 | [
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[Use of semipermeable membranes in several histochemical reactions]. | A method for using semi-impermeable membranes in histochemical reactions is described by the example of studying the activity of acid phosphatase in white mouse kidneys. The advantage of this method over the classical histochemical methods of detection of the acid phosphatase activity in the kidney is that it does not ... | 686,995 | [
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0.0... |
[Pathological aspects of acute suppurative infections of different etiology and localization]. | In the past decade the rate of purulent infectious complications caused by staphylococci and gram-negative bacteria of the genera Pseudomonas and Enterobacteriaceae which are highly resistant to antibiotics has increased. In therapeutic institutions these microbes cause group contageous diseases which are called "hospi... | 687,010 | [
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[Principles of growth in the acetabulum. Consequences for the shelf operations (author's transl)]. | Not unlike a Mercedesstar the arms of the Y-growthzone divide the cup of the acetabulum into three equal segments. The three branches of the Y-zone are spheroid. So the socket can expand evenly and conform to the head by feed back. Otherwise the socket would fill up. For the cartilage of the concave acetabulum prolifer... | 687,025 | [
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... |
Idiopathic scoliosis: an electromyographic study. | Thirty-one patients from 12 to 19 years of age having idiopathic scoliosis underwent electromyography of the paraspinal musculature using a Teflon-coated monopolar electrode. The studies conducted with the patients both prone and standing revealed no abnormalities on electrode insertion suggestive of a neuropathic proc... | 687,038 | [
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0.3374956,... |
[The symptom of EEG-flattening accompanying psychomotor attacks, their frequency, duration, form and significance. A video-band analysis of 78 patients with 187 attacks (author's transl)]. | A total of 187 psychomotor attacks in 78 epileptic patients were recorded on video band; 48 patients (61.5%) and 100 attacks (55.5%) showed signs of EEG flattening. This flattening became manifest before the clinical onset of the fit in 11.88% of patients, simultaneously with the fit in 30.5%, during the fit in 17.1%, ... | 687,067 | [
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0... |
[Changes in lactate dehydrogenase levels in acute articular rheumatism, chorea minor and the Schönlein-Henoch syndrome in childhood]. | Changes in serum LDH in AAR, Sydenham's chorea and purpura rheumatica and their significance were investigated in 103 cases observed at the 1st Paediatrics Clinic, University of Turin. A search was made for relation between such changes and the laboratory parameters in rheumatism. The data showed that blood LDH can be ... | 687,068 | [
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Intestinal obstruction due to phytobezoars. Observations in two patients with hypothyroidism and previous gastric surgery. | Two patients had small-bowel obstruction due to phytobezoars. Both patients were hypothyroid. One patient had undergone a previous pyloroplasty for pyloric stenosis and the other a truncal vagotomy and a pyloroplasty for a duodenal ulcer. Similarities and differences between the two cases and the possible predisposing ... | 687,078 | [
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... |
Left-sided colectomy with retroileal colorectal anastomosis. | Following resection of the sigmoid and descending colon for cancer or extensive diverticular disease, it may be impossible to make a colorectal anastomosis due to inadequate length of the residual transverse colon. To correct this problem, the remaining transverse colon may be pulled into the pelvis by making a "window... | 687,079 | [
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0.1556669,
... |
[From the analysis of the inadequacies of a 200-bed zonal hospital to an alternative proposal of a single general hospital to be used by the whole territory]. | The adequacy of the hospital to meet patients' needs was analysed on the basis of patients admitted to the Medicine Division over a 6 month period. Critical discussion of the numerous deficiencies encountered shows: 1) that the small zonal hospital of 200 beds is inadequate to perform the tasks and function of modern m... | 687,076 | [
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Rational management of the asymptomatic carotid bruit. | A noninvasive cerebrovascular evaluation has been devised that combines three separate but complimentary procedures: ocular pneumoplethysmography (OPPG), carotid audiofrequency analysis (CAA), and cerebral Doppler analysis. This evaluation has proven particularly useful in examination of the asymptomatic carotid bruit,... | 687,087 | [
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0.02413796,
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0.08082163,... |
Doppler ankle systolic blood pressure. Prognostic value in vein bypass grafts of the lower extremity. | The prognostic value of Doppler-derived ankle systolic pressure indices for predicting the patency of vein bypass grafts in the lower extremity was analyzed in 126 vein bypass grafts performed for limb salvage. Early or late graft failure was not found to correlate with the preoperative ankle systolic pressure index (A... | 687,088 | [
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Role of portal venous blood supply from the pancreas in maintaining hepatic functional reserve. Appraisal of Warren's shunt operation. | Mitochondrial phosphorylative activity was measured in the livers of various shunted or pancreatectomized dogs. In simple portal vein branch-ligated dogs, the mitochondrial phosphorylative activity in the nonligated lobe, which was supplied with excess portal blood, increased to approximately 150% of control values. In... | 687,095 | [
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0.02864897,
0.04403149,... |
[Effect of general vertical vibration and polychlorocamphene on the kidneys of inbred rats]. | During two months, effects of general vertical vibration, polychlorcamphen and combination of these two factors were studied in the kidneys of 60 immature male rats of August and Wistar strains. Twenty animals were used as controls (10 per each strain). Under experimental conditions, decrease in body weight, in kidney ... | 687,123 | [
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0.09859566,
-0.2087... |
Clinical experience with continuously monitored fluid balance in automatic hemofiltration. | Automatic fluid balancing, as obtained with the hemofiltration machines from Sartorius (Göttingen, West Germany) and Dialysetechnik (Karlsruhe, West Germany), is accurate enough to replace bed scales, which have been necessary in conventional hemodialysis for patients who are confined to beds. Side effects such as hypo... | 687,171 | [
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... |
Hemodiafiltration: a new alternative to hemofiltration and conventional hemodialysis. | A new dialysis method, termed hemodiafiltration, is proposed. The procedure consists of the combination of hemofiltration and conventional hemodialysis using high flux membranes with a transmembrane pressure (TMP) of 300--500 mmHg and a dialysate flow of 900 ml/min. Due to the combination of convective mass transfer an... | 687,172 | [
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0.099... |
Scanning electron microscopic evaluation of the surfaces of artificial hearts. | This report summarizes the surface changes seen in artificial hearts implanted in calves for periods up to four months. Fabrication defects as well as degradation resulting from wear are identified. SEM evaluation of the blood contacting surface as well as the surface of the diaphragm associated with the drive mechanis... | 687,174 | [
-0.1740058,
0.2104821,
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0.1982212,
0.01178005,
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-0.05647838,
-0.07902446,
0.05300776,
-0.03921354,
0.1496917,
-0.1198166,
0.06086502,
0.04665764,
-0.5017257,
0.1127193,
-0.419394,
-0.1506583,
-0.1934125,
-0.1189235,
-0.04931182,
0.2512439,
-0.0048472... |
Use of discriminant analysis. II. Identification of persons with glaucomatous visual field defects. | Thirty-three ocular, systemic, and laboratory variables were used in a discriminant analysis to separate 219 patients suffering from chronic open-angle glaucoma from 100 people who did not have the disease. The analysis used seven of the variables to separate 93% of the patients correctly. Without intraocular pressure,... | 687,196 | [
-0.07945658,
0.08047079,
-0.1554861,
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0.2425987,
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0.09085268,
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0.2284961,
0.05449416,
0.2615008,
-0.0926689,
0.0241818,
-0.06803... |
Small melanomas of the choroid. | We reviewed 38 cases of small choroidal melanomas on file in the Eye Pathology Laboratory of Bascom Palmer Eye Institute, Miami. Clinical and histopathological features of these cases were noted, and clinical follow-up information was obtained for 36 (95%) of the patients. Two tumor deaths occurred among the 18 patient... | 687,198 | [
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0.2917313,
0.1590263,
0.2366244,
0.1686607,
0.3151042,
0.005875176,
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0.... |
The iris sphincter in aberrant regeneration of the third nerve. | Fourteen patients with aberrant regeneration of the third cranial nerve were examined using self-developing photographs, motion pictures, and pupillography. These pupillary phenomena were noted: (1) sector contractions of the iris sphincter in response to light, (2) sector contractions of the iris sphincter associated ... | 687,202 | [
-0.07417109,
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0.2772219,
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-0.383377,
0.3144972,
0.0206423,
-0.0550410... |
The effects of middle ear muscle contraction on auditory and overload thresholds. | The present investigation examined psychophysically the frequency-specific and nonlinear attenuation of sound energy provided by middle ear muscle contraction in normal hearers. Aural overload and absolute auditory thresholds were measured at 500, 1 000 and 2 000 Hz prior to and during acoustic stapedial reflex contrac... | 687,241 | [
0.01894774,
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0.05076849,
0.1721859,
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0.01700833,
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0.06612202,
0.03571196,
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-0.5487555,
0.2121852,
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0.2213922,
-0.04280502,
0.12980... |
Urolithiasis in animals. | Urolithiasis is a disease of multifactorial origin. Prominent amongst the causes of disease outbreaks are nutritional factors. Alteration of diet is probably one of the most effective means of prevention, depending of course on the nature of the uroliths formed. In this regard analysis of the stones formed is an essent... | 687,293 | [
-0.1249951,
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0.004894347,
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0.06144453,
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0.1142207,
0.2050987,
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0.1197658,
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0.1193809,
0.1305721,
0.006946775,
0.02997959,
0.1655059,
-0.2507522,
... |
Some transport properties of resealed washed human erythrocyte membranes. | A comparison was made between the phosphate- and glucose-transport systems of intact erythrocytes and resealed washed membranes. Glucose transport exhibits identical properties in both cases, but the phosphate-transport system does not appear to have survived the membrane isolation procedure unaltered. Evidence is pres... | 687,362 | [
-0.09747761,
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0.158156,
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0.2695171,
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0.07485157,
0.2430262,
0.192964,
-0.08763812... |
Childhood Hodgkin's disease in Uganda: a ten year experience. | Between 1967 and 1977, 48 patients with Hodgkin's disease under 16-years-old were treated with MOPP chemotherapy alone at the Uganda Cancer Institute because radiotherapy facilities are not available. Thirty-eight percent had early stage disease (stages I-IIIA). Prolonged first remissions were achieved in 74% of 42 com... | 687,386 | [
0.075142,
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0.08318829,
0.2744517,
0.1711655,
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0.1971468,
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0.0420567,
0.1742273,
0.265416,
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0.297408,
0.2250622,
-0.173747,
0.11965... |
[Progressive fibrodysplasia assificans]. | A five years old patient with myositis ossificans progressiva is presented. This very rare disease is inherited as an autosomal dominant and it is characterized by an abnormality of the connective tissue, specifically, aponeurosis, fascias, tendons and ligaments; the muscle are secondarly affected. | 687,403 | [
-0.2951225,
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0.2472322,
0.008388663,
0.07721265,
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0.03913005,
0.1831279,
0.3247191,
0.1201499,
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-0.5186942,
-0.2338479,
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0.08821684,
0.5283855,
-0.03188226,
-0.1746505... |
[Normal pressure hydrocephalus. Part 2. The evaluation of severity of cerebral dysfunction by measurement of "barrier ratio" and regional cerebral blood flow (author's transl)]. | In the previous study, quantitative analysis of RI ventriculography was reported in fifty-three cases with chronic communicating hydrocephalus. In this study, according to the same criteria as that of previous report, fifty-three cases were divided into two groups, namely NPH group (twenty-seven cases) and control grou... | 687,459 | [
-0.1051919,
0.1313754,
0.03584507,
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0.3185031,
0.07191298,
0.172369,
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0.03673408,
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0.2823405,
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0.04622271,
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0.2393147,
0.3857809,... |
[Convexity cavernous hemangioma, its angiographic and CT findings. Report of a case (author's transl)]. | A case of cavernous hemangioma which developed in the parietal convexity is reported. Angiography reveals that the mass is located extra-axially in the parietal convexity and the middle meningeal artery feeds the tumor. The feature of tumor stain is pooling or laking of contrast medium which is partially visualized eve... | 687,461 | [
-0.2644857,
0.2829353,
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0.0537668,
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0.03936189,
0.1639371,
0.2421685,
0.1302977,
0.05072686,
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0.02918404,
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0.2720189,
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-0.06272531,
0.2893275,
0.1065089,
0.05985073,
... |
Near fatal puerperal thrombosis on Björk-Shiley mitral valve prosthesis. | A 22-year-old woman required emergency mitral valve replacement three weeks post partum because of thrombotic obstruction of her prosthetic mitral valve. Low dose subcutaneous heparin was administered from the 17th week of pregnancy. Though there was a successful fetal outcome, heparin did not prevent thrombosis on the... | 687,495 | [
-0.1311963,
0.1848528,
-0.3465856,
0.1925044,
0.07716535,
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0.02713843,
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-0.005169782,
0.3374753,
0.2115895,
0.05057603,
0.2474323,
0.2742432,
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0.2222142,
0.1155898,
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0.01855909,
0.4724856,
0.2040839,
0.1... |
Clobazam--a new hypnotic? | 1 A double-blind randomized trial to compare the relative efficacy of the 1,5-benzodiazepine, clobazam, the 1,4-benzodiazepine nitrazepam, and placebo as hypnotics was carried out. 2 A preference technique was used and the analyses were performed sequentially. 3. The results confirmed that nitrazepam was superior to pl... | 687,502 | [
-0.2741604,
0.2438705,
-0.3455151,
-0.1656026,
0.1032845,
-0.1075905,
-0.4864148,
-0.3869447,
-0.1525548,
-0.284199,
0.1653037,
0.4002454,
0.06139027,
0.2268413,
-0.1279619,
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0.1794387,
-0.1344157,
0.07413479,
0.06680588,
0.1599126,
0.120042,
0.12... |
Morphological study of the ovaries of leukaemic children. | The ovaries of leukaemic children were studied in 31 specimens obtained at autopsy. Twenty-eight ovaries from normal children of the same age who died from misadventure served as control. All ovaries from normal childred showed follicle growth and contained several large antral follicles. Follicle development was inhib... | 687,521 | [
0.1075976,
0.1027315,
-0.02794101,
0.008463064,
0.2295444,
-0.1647798,
0.09807596,
0.05993357,
-0.1563638,
-0.011414,
0.07704158,
0.5904924,
-0.004201713,
0.3381089,
-0.0698982,
-0.1268648,
-0.01819781,
0.2791821,
0.04869597,
0.3577788,
0.3080763,
0.0659633,
-0.1751847,
... |
Mammary-carcinoma cells in mouse liver: infiltration of liver tissue and interaction with Kupffer cells. | Interactions between TA3 mammary-carcinoma cells and liver cells were studied with the electron microscope in mouse livers that had been perfused with a defined medium containing the tumour cells. Infiltration of liver tissue by the TA3 cells proceeded in the following steps. First, numerous small protrusions were exte... | 687,522 | [
-0.004159459,
0.05691902,
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-0.06889343,
0.1004233,
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0.2528149,
0.2231069,
0.1029276,
0.1752756,
-0.1660254,
-0.1084898,
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-0.4139186,
-0.2299782,
-0.551369,
-0.1635532,
0.2326508,
0.02406587,
0.01706642,
0.1660168,
0.1394536,
... |
On the validity of the Middlesex Hospital Questionnaire: a comparison of diagnostic self-ratings in psychiatric out-patients, general practice patients, and 'normals' based on the Hebrew version. | The short clinical diagnostic self-rating scale for psycho-neurotic patients (The Middlesex Hospital Questionnaire) was translated into everyday Hebrew and tested on 216 subjects for: (1) concurrent validity with clinical diagnoses; (2) discriminatory validity on a psychoneurotic gradient of psychiatric out-patients, g... | 687,531 | [
-0.1247122,
0.0242432,
-0.1221443,
-0.3564995,
-0.08327673,
-0.1926016,
-0.6862783,
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-0.1040272,
-0.313137,
0.1114011,
-0.1601522,
0.3899275,
0.05201675,
-0.4675681,
0.1800572,
-0.04624371,
0.06762516,
-0.3206307,
0.01736137,
0.06458805,
0.1402601,
0.2208006,
... |
Hypovolaemia, pre-eclampsia and diuretics. | Six patients with severe pre-eclampsia were found to have low central venous pressures. This was considered to be an indication that hypovolaemia was present, depsite concurrent generalized oedema. Treatment with sufficient intravenous saline and albumin, to restore the central venous pressure to normal, resulted in im... | 687,538 | [
-0.04146183,
0.273037,
-0.110549,
0.03440307,
0.3434604,
-0.2193853,
-0.07299377,
-0.2185968,
-0.1364412,
0.1772918,
0.2957132,
0.07246358,
-0.1571493,
0.3181389,
-0.1196396,
-0.2540634,
-0.1060182,
0.1944524,
-0.1094536,
-0.2591083,
-0.1941365,
-0.0527945,
-0.002370749,
... |
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