title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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The perifoveal vasculature in albinism. | The perifoveal vasculature was studied in a series of patients with oculocutaneous tyrosinase-positive albinism. Fluorescein angiographic studies show a normal distribution of the major retinal blood vessels and in some cases of the capillaries in the macular area of these patients. | 687,555 | [
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Orbital blood cyst. | A blood cyst of the orbit is an unusual cause of proptosis and most likely arises in a pre-existing haemangioma. If the cyst occurs at the apex of the orbit the blood should be aspirated. This is followed by excision of the cyst wall, the dissection being done with the aid of an operating microscope. If there is eviden... | 687,558 | [
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Amount and properties of uptake forms in preparations of alpha-mannosidase from pig kidney. | alpha-Mannosidase (alpha-D-mannoside mannohydrolase, EC 3.2.1.24) from pig kidney has been shown to exist in multiple forms differing in their capability to be endocytosed by alpha-mannosidase deficient cultured cells. A method is presented to evaluate the amount of "uptake" forms in different preparations of the enzym... | 687,630 | [
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Production of protein HC by human fetal liver explants. | Human fetal lever explants were found to secrete protein HC into the medium in molar amounts comparable to those of albumin, alpha 1-antitrypsin and orosomucoid. Incorporation of a radioactive amino acid from the medium into the secreted protein HC demonstrated de novo synthesis. The secreted protein HC had the same si... | 687,667 | [
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[Immobilization of coenzyme A on a hydrosoluble polymer]. | Our purpose being to work out a "continuous flow" enzymatic reactor of acetylation with a cofactor, we present here some results about the immobilization of coenzyme A on T40 dextran. Two methods of fixation are compared with regard to the capacity and the biological activity of the polymers thus obtained. | 687,679 | [
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Effects of pharmacologic agents on umbilical blood flow in fetal lambs in utero. | We studied the effects of pharmacologic agents on umbilical blood flow and umbilical-placental vascular resistance in 18 fetal lambs in utero. Three groups of drugs were identified: the first had no effect on umbilical blood flow or umbilical-placental vascular resistance; the second altered umbilical blood flow second... | 687,691 | [
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In vivo interactions between novel filler free silicone rubber and blood. | To evaluate the thrombogenicity of the novel filler free silicone rubber (FFSR) prepared in our laboratory, its interactions with blood were studied. The test samples (FFSR) along with control Silastic samples were placed in an extracorporeal shunt and primed with sterilized normal saline. The blood from an anaesthetiz... | 687,717 | [
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Effect of gastric intubation of the gastric loss of serum albumin. | In a group of 18 inpatients, the catabolism of serum albumin rate, in percentage of intravascular albumin pool, was measured during two successive periods of 7 days. In the first experimental period, we did no intubation, while during the second, a tube was kept in the stomach, with an overnight intragastric perfusion ... | 687,747 | [
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Starvation and sucrose activity in small intestinal mucosa. An evaluation of different tissue preparations and reference systems. | Starvation for 48 hrs reduced the activity of sucrase referred to unit length in rat proximal small intestine by approximately 30%, irrespective of whe her mucosal scrapings, isolated villus epithelial cells or brush border membranes were investigated. Sucrase activity referred to unit weight, unit protein or to unit D... | 687,756 | [
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Lecithin bilayers. Density measurement and molecular interactions. | Density measurement are reported for bilayer dispersions of a series of saturated lecithins. For chain lengths with, respectively, 14, 15, 16, 17, and 18 carbons per chain, the values for the volume changes at the main transition are 0.027, 0.031, 0.037, 0.040 and 0.045 ml/g. The main transition temperature extrapolate... | 687,759 | [
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Interaction between batrachotoxin and yohimbine. | The neurotoxins, batrachotoxin and veratridine, are specific activators of sodium channels and cause an increase in the rate of 22Na uptake in neuroblastoma cells. Yohimbine, an indolakylamine alkaloid, inhibits this batrachotoxin-induced 22Na uptake. The dose-response curve of yohimbine suggest that the inhibitor acts... | 687,761 | [
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An analysis of the electrical properties of a skeletal muscle fiber containing a helicoidal T system. | The linear electrical properties of skeletal muscle fibers have been analyzed using lumped circuit analogues of helicoidal T system. The geometry of a helicoid is assumed to produce two electrical effects, modeled separately. One model is motivated by the pitch or tilt of the T system, which forces the current flowing ... | 687,765 | [
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Current noise around steady states in discrete transport systems. | Subject of this paper is the transport noise in discrete systems. The transport systems are given by a number (n) of binding sites separated by energy barriers. These binding sites may be in contact outer reservoirs. The state of the systems is characterized by the occupation numbers of particles (current carriers) at ... | 687,770 | [
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Applications of purification reactions for minimizing reaction-generated enzyme poisoning. | A mathematical model has been employed to examine the interplay of reaction and mass transfer in immobilized enzyme systems involving reaction-generated enzyme poisions. Deactivation rates can be significantly reduced in some cases by catalyzing a purification reaction in which the poison is transformed into an innocuo... | 687,790 | [
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[Functional interaction between the determinant and other foci of epileptiform activity created in the cortex of both cerebral hemispheres]. | It was shown in experiments on cats under nembutal anesthesia that creation of a hyperactive focus with a high excitation level in the orbital or coronary cortex of one hemisphere and of a number of foci in the neocortex of the contralateral hemisphere led to formation of a functional complex working in a unified regim... | 687,805 | [
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[Functional state of the liver following massive transfusion of packed red cells]. | Hepatic function was studied in experiments on 16 dogs after massive transfusion of red cell pack to ascertain the blood components influencing this function most. Massive transfusion of red cell pack failed to induce any significant changes in the excretory-absorbing protein forming function, and also in the content o... | 687,809 | [
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[Multicomponent system of estrogen-binding proteins of liver cytosol: species differences in rats, mice and guinea pigs]. | Estradiol (E2) binding proteins from the liver cytoso-of mature male and female rats, mice, guinea pigs, and rabbits were investigated by gel filtration on Sepharose 6B columns. Components with Stokes radii (a) 6--7 and 2.5 nm which form specific stable complexes with E2 were found in female rats and female and male mi... | 687,819 | [
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[Long-term transplantation of mature sensory neurons]. | The spinal ganglia were transplanted into the mesocolon of adult cats for periods of from 1 day to 9 months. About 30% of differentiated sensory neurons survived during the longterm transplantation. The intensive regeneration of the sensory neurons processes was characteristic of the transplanted neurons. Total myelini... | 687,820 | [
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Absence of beta mRNA in beta0-thalassemia in Kurdish Jews. | We report the characterization of the amount of beta mRNA in a Kurdish Jewish population with beta0-thalassemia using the same methods employed for characterization of the Catania and Ferrara beta0 patients. We found very low amounts of beta mRNA sequences, consistent with the presence of beta0-thalassemia of the beta ... | 687,828 | [
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Mechanisms underlying overshoot dilation after sympathetic denervation. | (1) 30--60 sec after transection of the sympathetic chain, the diameter of both femoral artery and vein dilates to approximately 120% of the control diameter ('overshoot dilation'). Vessel diameter subsequently decreases and stabilizes with 5--10 min at a value of 108% of the original ('stabilized dilation'). (2) After... | 687,833 | [
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The mechanism of the relaxant effect of 2-2'-pyridylisatogen on the isolated taenia of the guinea-pig caecum. | 1 2-2'-Pyridylisatogen tosylate (PIT) slowly relaxed taenia caeci preparationg of the guinea-pig in a concentration-dependent manner (threshold 2.5 muM). The relaxant effect did not show tachyphylaxis.2 The relaxation was not affected by tetrodotoxin (0.3 muM), guanethidine (17 muM) nor by a combination of phentolamine... | 687,877 | [
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Some psychological, educational and criminological variables related to recidivism in delinquent boys. | The HDHQ, 16 PF and PSI were administered to 315 detainees at Medomsley Detention Centre, Durham, along with tests of intelligence and attainment, and measures of previous criminal history. One hundred and ninety-one boys were subsequently reconvicted within two years of their release. They were found to have lower sco... | 687,880 | [
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A study of potential Olympic swimmers. Part 2. Changes due to three months intensive training. | Anthropometric and physiological measurements were recorded for a group of exceptional young swimmers undergoing an intensive training programme over 3 months. The observed changes are presented and are discussed in relation to the training undertaken, and are compared with expected changes due to normal growth. Some o... | 687,889 | [
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Heparin-like activity in uterine fluid. | Uterine fluid was collected from a group of normal patients and a group of patients with menorrhagia. Heparin-like activity was detected in 34 out of 38 samples using an anti-Xa heparin assay. The heparin-like activity in uterine fluid was inhibited by adding the heparin antagonist hexadimethrine bromide to the assay. ... | 687,899 | [
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Disproportionate reduction in tryptic response to endogenous compared with exogenous stimulation in chronic pancreatitis. | The secretin-pancreozymin (SP) and Lundh-Borgström (meal) tests were compared in diagnosing chronic pancreatitis (CP). A range of normal values for each test was obtained in a control group of 22 patients without pancreatic disease. Seventeen patients with CP were given the tests on separate days. The peak concentratio... | 687,935 | [
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Deflection of selected optic fibers into a denervated tectum in goldfish. | In goldfish, one eye was enucleated, and after two or more weeks a select fraction of optic fibers from the remaining eye was deflected into the ipsilateral optic tectum. At varying intervals, the optic reinnervation of the ipsilateral tectum was measured by autoradiography and electrophysiologic mapping. Both methods ... | 688,017 | [
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A study of the influence of the method of oral administration of ampicillin upon plasma drug levels in calves. | Ampicillin was given orally to five Holstein calves using the following four different methods of administration: via stomach tube, mixed and fed in the calf starter ration, dissolved in milk and pail fed and administered orally as 400 mg commercial calf tablets. In addition, ampicillin was dissolved in milk and pail f... | 688,070 | [
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On establishing reference values. | In order to establish a range of reference values for any characteristic one can use Gaussian or nonparametric techniques, whichever are most appropriate. One has the choice of calculating tolerance intervals or percentile intervals. A tolerance interval is said to contain, say 95% of the population with probability,... | 688,072 | [
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0.07637909,
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0.07156199,
0.4042983,
-... |
Enigmatic resistance of sheep (Ovis aries) to infection by virulent Francisella tularensis. | Tularemia in range sheep is an occasional cause of severe economic loss from mortality and unthriftiness as well as a hazard to persons in contact with the animals. Epizootics are unpredictable and explosive, therefore, prophylaxis is more practical than therapy. Live vaccine of proven value in man and in beavers was i... | 688,073 | [
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Absence of Na+--H+ barrier function in mucosa of canine small bowel. | The study was designed to determine whether the special Na+--H+ barrier function of the gastric mucosa is present in the mucosa of the small bowel and whether a gastric mucosal barrier breaker (hexanoic acid) would accelerate the fluxes of sodium in duodenum-jejunum and ileum as in the stomach. The observations were ma... | 688,085 | [
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Epileptiform seizures in domestic fowl. VIII. Anticonvulsant activity of primidone and its metabolites, phenobarbital and phenylethylmalonamide. | Primidone is an effective anticonvulsant against seizures induced in epileptic fowl by exposure to intermittent photic stimulation. Epileptic fowl metabolize primidone to phenobarbital. Pretreatment of epileptic fowl with SKF 525A to prevent the metabolism of primidone to phenobarbital indicated that primidone itself h... | 688,087 | [
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Acute tolerance to ethanol on the release of acetylcholine from the cat cerebral cortex. | Ethanol (1 g/kg, iv) produced a peak depression of acetylcholine release from the cat sensorimotor cortices within 30 min of the ethanol administration but recovery to control levels occurred in the following 30 min. However, the concentrations of ethanol in the blood and in the solution bathing the cortex remained sta... | 688,092 | [
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The interaction of cholera toxin subunit A with cultured adrenal cells. | Subunits A and B of cholera enterotoxin were isolated by chromatography on a Bio-Gel P-60 column in the presence of 4% formic acid. The purity and biological activity of the isolated subunits was assessed by polyacrylamide disc gel electrophoresis and mouse adrenal cell assay, respectively. The specific uptake of isola... | 688,100 | [
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Estimation of bacterial production in fresh waters by the simultaneous measurement of [35S]sulphate and d-[3H]glucose uptake in the dark. | Sulphate uptake in the dark by phytoplankton constitutes a severe limitation to the determination of bacterial heterotrophic production from sulphate-uptake rates. Consequently a modification to the 35S-method has been developed involving size fractionation to separate the algae from the bacteria. Both the whole water ... | 688,101 | [
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Future prospects in lymphoma and leukemia. | Possible advances in leukemia and lymphomas can, in my opinion, derive from continued consideration of viral etiopathogenesis, possibly demonstrated by therapeutic impact of antiviral therapy. Terminology is in constant flux, and a classification based on biochemical (such as asparagine dependence) and immunologic (suc... | 688,175 | [
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Isolation of a factor with toxohormone properties from mouse tumor cells in culture. | A small molecular weight factor with potent toxohormone activity was recovered from the serum-free culture supernatant of mouse MBQA fibrosarcoma cells. The factor depressed plasma-bound iron levels in mice and inhibited cell-free protein synthesis in microgram doses. Preliminary characterizations suggest that the act... | 688,182 | [
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... |
Two crops of primary lung tumors in BALB/c mice after a single transplacental exposure to urethane. | Transplacental exposure of BALB/c mice to urethane on day 17 of gestation resulted in the appearance of 2 distinct crops of primary lung tumors (adenomas). The first, smaller crop occurred in 6--12% of the offspring by 12 weeks of age. The second crop, seen after 9 months of age, consisted of tumors in 45% of the offsp... | 688,183 | [
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Promotion of azoxymethane-induced colonic neoplasia by resection of the proximal small bowel. | Potential enhancement of intestinal neoplasia by compensatory mucosal hyperplasia was tested in rats subjected to 50% proximal small bowel resection (PSBR) 10 days after the last of 16 weekly injections of azoxymethane. Azoxymethane alone increased jejunal contents of RNA and DNA each by 26% at 17 to 18 weeks (p less t... | 688,211 | [
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Mouse skin carcinogenicity tests of the flame retardants tris(2,3-dibromopropyl)phosphate, tetrakis(hydroxymethyl)phosphonium chloride, and polyvinyl bromide. | The flame retardants tris(2,3-dibromopropyl)phosphate, tetrakis(hydroxymethyl)phosphonium chloride, and polyvinyl bromide were tested for carcinogenic activity by skin application 3 times weekly in random-bred female ICR/Ha Swiss mice for 420 to 496 days. Tris(2,3-dibromopropyl)phosphate at two dose levels (30 mg and 1... | 688,215 | [
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0.3582033,
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Effects of adriamycin on DNA synthesis in mouse and rat heart. | Adriamycin induces an inhibition of DNA synthesis in mouse tissues within one hr after treatment. While the effects are short-lived in liver and small intestine, DNA synthesis in heart remains below control values for up to 7 days. After this period DNA synthesis in hearts of treated mice is elevated and remains above ... | 688,218 | [
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Establishment and characterization of three new continuous cell lines derived from human breast carcinomas. | Three continuous lines of mammary tumor cells (ZR-75-1, ZR-75-27, and ZR-75-30) have been established from malignant effusions of two women with breast cancer. Differentiated properties expressed by each cell line include: (a) epithelial morphology (by light and electron microscopy) resembling that of the parental tumo... | 688,225 | [
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The effect of haemorrhage on the cell populations of the thymus and bone marrow in wild starlings (Sturnus vulgaris). | Following the withdrawal of blood from the brachial vein of adult wild starlings (Sturnus vulgaris) changes in the cell populations within the bone marrow and thymus were observed over an eight day period. The packed cell volume, haemoglobin content and reticulocyte count of the peripheral blood was determined before a... | 688,342 | [
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0.01469434,
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Ultrastructural dynamics of the corpus allatum of Choleva angustata Fab. (Coleoptera, Catopidae). | The ultrastructure of the corpora allata (CA) during postembryonic stages of Choleva angustata Fab. shows cyclic changes, in particular regarding the endoplasmic reticulum and the mitochondria. During the last larval instar, at the short transitory period which follows the cessation of alimentation, we observed a highl... | 688,352 | [
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Direct connections between mitochondria and catecholamine-storage vesicles demonstrated by high voltage electron microscopy in rat adrenal medulla. | Tubular channels from mitochondria to catecholamine-storage vesicles have been demonstrated in thick sections of adrenal medullary tissue from hypoglycemia-stressed rats by the use of the high voltage electron microscope. The function of these connections is not presently known although they may serve as channels for t... | 688,363 | [
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Structure of occluding junctions in ileal epithelial cells of suckling rats. | Two kinds of occluding junctions are found between ileal epithelial cells of suckling rats: apical zonulae occludentes (ZO) and fasciae occludentes (FO) which are associated with the lateral plasma membranes of many epithelial cells. In unfixed preparations, glycerol treatment induces the further proliferation of exten... | 688,364 | [
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[Aortic valve stenosis with calcification]. | A group of 52 patients was studied with a view to defining the characteristic features of aortic valve stenosis with calcification. There is no uniform aetiopathogenesis to explain the condition. 3 basic types could be distinguished--post-rheumatic, senile, and due to congenital malformation of the valve; all were repr... | 688,474 | [
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[Nature of the pigment in multilayer neurofibromas]. | Two cases of storiform neurofibroma were examined electronmicroscopically. Their pigment was identified as melanin both by histochemical methods and by the presence of melanosomes. In one case moreover another pigment of lysosomal location was found. | 688,477 | [
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[Cellular irregularities in nasal polyps]. | 50 patients of different ages were found to have irregular multinuclear cells lodged in their inflammatory hyperplastic nasal mucosa. In only isolated cases were they numerous enough to give the tissue a sarcomatoid appearance. Most of those could clearly be described as proliferating endothelial cells. Mechanical irri... | 688,478 | [
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0.04299316,
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[Adenomatoid hamartoma of the lung]. | The right lung of a stillborn premature infant was found to have a growth occupying most of the pleural cavity and displacing the mediastinum. It was predominantly solid with minor cysts and with structure reminiscent of a clusters of primitive alveoli and bronchioles, or else it contained major gaps with papillomatous... | 688,480 | [
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0.5964893,
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0.04923286... |
Carcinogenicity and metabolic profiles of 3-methylcholanthrene oxygenated derivatives at the 1 and 2 positions. | Trapping of 3-methylcholanthrene (MC) radical cation by nucleophilic compounds occurs specifically at the 1-carbon atom. With the purpose of providing more evidence for the hypothesis that the critical mechanism of activation of MC is one-electron oxidation, the carcinogenicity of MC was compared to that of 1-hydroxy-3... | 688,526 | [
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[Gardner's syndrome in familial popyposis: clinical contribution and etiopathogenetic, therapeutic and prognostic considerations]. | Starting from one case of Gardner's syndrome of their own observation, and in light of Watne's results, the authors argue that in the syndrome just named--and in familial polyposis in a broader sense--genetic factors do not play a predominant role; rather, polyps seem to result from the prolonged action of noxious agen... | 688,542 | [
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0.3833267,
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0.09... |
[Primary carcinoid of the testis. Clinical case]. | A very rare case of carcinoid of the testicle combined with teratoma is illustrated. In fact the literature of the last twenty years reports only eleven cases of carcinoid of the testicle, of which only four combined with teratoma. It is stressed that it is possible that these neoplasias arise on already existing terat... | 688,552 | [
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0.04863982,
... |
Contribution of systemic venous hypertension to the development of pulmonary edema in dogs. | Systemic venous hypertension (SVH) is a frequent finding in pulmonary edema. To study the possible contributory or even causal role of SVH in pulmonary edema, a dog model was developed in which balloon catheters were placed in the left and right atria. Inflation of the left atrial balloon produced a tendency to pulmona... | 688,559 | [
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0.01835214,
0.1970708,
-0.078704... |
Left ventricular volume during maximal supine exercise: a study using metallic epicardial markers. | Changes in left ventricular (LV) volumes and ejection fraction between rest and maximal supine exercise were evaluated in 11 patients who had had four epicardial markers placed during coronary artery surgery. After calibrating marker distances with respect to volume (r = 0.92--0.99) over one cardiac cycle for each pati... | 688,582 | [
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0.5225682,
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External quality-control survey of cholesterol analyses performed by 12 lipid research clinics. | We report accuracy and precision achieved in the automated analysis for cholesterol in a long-term multilaboratory study, presenting and evaluating the significance of data accumulated by 12 Lipid Research Clinics (LRC's) in the analysis of 18 unknown surveillance pools during three years. The average bias for all pool... | 688,605 | [
0.1233577,
0.2299452,
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0.227213,
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0.1110... |
Analysis for salicylic acid in serum by high-performance liquid chromatography. | We report a specific and sensitive quantitative assay for salicylate in serum or plasma. As little as 3 microliter of sample can be analyzed by an external standard procedure and larger volumes by diluting with the internal standard (o-methoxybenzoic acid). No extraction or derivatization is necessary and salicylic aci... | 688,615 | [
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Circulating antigens and immune complexes in Schistosoma mansoni-infected rats. Characterization by radioimmunoprecipitation-PEG assay (RIPEGA). | Circulating schistosome antigens (CSA) and circulating immune complexes (CLC) were investigated in rats infected with Schistosoma mansoni. The radioimmunoprecipitation-polyethylene glycol (PEG) assay (RIPEGA), with 125I-labelled anti-S. mansoni anti-serum, detected CSA during two distinct periods of the infection; the ... | 688,695 | [
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0.03257186,
0.1620445,... |
Epiphysiolysis as a method of limb lengthening. | Epiphysiolysis followed by distraction was performed at the proximal tibial growth plates in 18 young rabbits. Union across the distracted plate occurred in all animals. In 12 rabbits skeletally immature at operation, premature fusion of the separated plate resulted in growth arrest of the operated limb. The contralate... | 688,713 | [
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... |
Digital replantation: clinical experiences. | In a series of 130 digital replantations successful revascularization has been obtained in 74% of cases. Arterial thrombosis is the most common cause (65%) of all failures. A useful digit can be obtained following replantation and the surgery is particularly indicated for amputated thumbs and in hands suffering multipl... | 688,715 | [
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0.1359537,
0.05899394,... |
Replantation of digits. | Replanted digital survivals range between 85% to over 90% at established microsurgery centers around the world. The time has come that all surgeons engaged in this activity must utilize the basic principles of reconstructive hand surgery in order to achieve the maximum functional return of the replanted parts. The vasc... | 688,716 | [
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Nerve grafting. | By avoiding tension and securing anatomical neurorrhaphy, regeneration of nerve is obtainable. When the gap exceeds a certain limit, the only way to avoid tension is the use of grafts. Experience in animal experiments and clinical practice has demonstrated that regenerating axons can cross 2 optimal suture lines much m... | 688,717 | [
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0.07894862,
0.06003409... |
Digoxin concentration in choroid plexus, brain, and myocardium in old age. | Thirteen aged persons receiving digoxin until the time of death were examined by autopsy, and digoxin concentrations were determined in samples from various tissues (the choroid plexus, grey and white brain matter, left and right ventricular and left and atrial myocardium, diaphragm, and musculus psoas major). These c... | 688,735 | [
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0.5977668,
0.08801819,
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0.... |
The triglyceride fatty acid pattern in arterial wall, adipose tissue and serum of amputated diabetic subjects. | The triglyceride fatty acid pattern [TFAP] in arterial wall, adipose tissue and serum has been estimated in diabetic subjects by gas-liquid chromatography simultaneously. The samples were taken shortly before or during femoral amputation performed under halothane anaesthesia. In addition, in some probands the fatty aci... | 688,757 | [
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0.1178636,
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Treatment of "tinea pedis" with griseofulvin and topical antifungal cream. | A protocol for determining the antifungal efficacy of systemic or topical drugs in tinea pedis is presented. In this study, (1) no patient had concomitant onychomycosis; (2) the clinical types were separated into (a) plantar scaling, (b) intertriginous, and (c) vesicular instep; (3) the soles were treated for three mon... | 688,767 | [
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0.06923247,
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0.4761684,
0.2928365... |
Hemodynamic effects of smoking cigarettes of high and low nicotine content. | We studied the hemodynamic effects of smoking cigarettes with high and low contents of nicotine in young smokers free of coronary arterial disease. The smoking of one cigarette with a high content of nicotine produced a peak rise in cardiac output of 32 percent above baseline values, and the effect persisted for one ho... | 688,779 | [
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0.07797772,
0.385666,
0.07493538,
-0.0360... |
Immune complexes in sarcoidosis: a correlation with activity and duration of disease. | Samples of serum from patients with sarcoidosis were examined for the presence of immune complexes, using the Raji cell line. An indirect immunofluorescent technique was used to detect the binding of immune complexes to the complement receptors of Raji cells. Preliminary studies indicated that the method was sensitive ... | 688,781 | [
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... |
Progressive development of a left ventricular thrombus. | In a patient with ischemic heart disease and terminal left ventricular failure, echocardiographic techniques (single-crystal M-mode echocardiograms and bidimensional, linear, dynamically focussed multiscan recordings) allowed the detection and follow-up of a left ventricular thrombus, later documented at autopsy. | 688,792 | [
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... |
Cleft tongue and ulceration of hard palate: complications of oral intubation. | In a prospective study of the complications of endotracheal intubation and tracheotomy, we encountered an unusual complication of oral intubation. This report describes a 32-year-old man who sustained laceration and cleft of the tongue and ulceration of the hard palate as a result of the use of an oral airway in conjun... | 688,796 | [
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0.005443859,
... |
[The Bayesian theorem in clinical differential diagnosis (author's transl)]. | New (a posteriori) probablities of medical diagnosis can be calculated by the Bayesian formula from a priori probabilities of the diagnosis or diagnoses under consideration and from the probabilities of a given test result occurring with each disease. Using sequential iteration, the Bayesian formula is applicable to th... | 688,871 | [
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0.1491524,
0.3623663,
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0.09144248,
0.... |
Accumulation and binding of 3H-estradiol-17beta by lymphoid tissues of castrated mice. | The in vivo uptake of 3H-estradiol-17beta by the various lymphoid tissues, fat tissue, skeletal muscle and circulating blood of castrated male and female mice of C57BL strain was studied after an intravenous injection of the hormone. In both sexes the highest uptake was by the bone marrow and fat tissue, followed by th... | 688,975 | [
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0.06212271,
0.4386655,
0.3180394,
0.1862488,
-0.1770406... |
The response to insulin by adipose tissue of insulin-dependent diabetics in vitro. | Subcutaneous adipose tissue was removed by surgical biopsy from 10 normal subjects and 4 insulin-dependent diabetics under exact intracutaneous anaesthesia. The adipose tissue fragments or isolated fat cells were incubated with a tracer amount of labeled glucose. In the presence of insulin (62.5 muU/ml) the production ... | 688,978 | [
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0.4019772,
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... |
[Effect of diet and thyroxine on body composition in rats]. | In young male Wistar rats the influence of different fat content of the diet (7 or 25 or 50 weight percent of fat) and of thyroxine (5 or 50 microgram/100 g body mass, 2 times/week, sc.) on body composition was investigated by carcass analysis. After high doses of thyroxine the percentage body fat decreases and protein... | 688,985 | [
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... |
Haemodynamics in the horse: 1. Pressure pulse contours. | Using a catheter with 2 transducers, one mounted at the tip and one 9 cm proximal to it, enabled transvalval pressure waveforms to be recorded in 8 horses. A simultaneous electrocardiogram acted as a time base. The changing waveforms produced in the chambers of the heart and great vessels are described and related to t... | 689,002 | [
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0.2263771,
0.3007615,
0.008... |
Lactate kinetics after short strenuous exercise in man. | Arterial blood lactate was measured at 10 s time intervals after a 3 min strenuous exercise for six athletes pedaling a bicycle ergometer in the sitting position. Recovery curves were fitted to the equation: Y(t) = A1(1-e-gamma1t)+A2(1-e-gamma2t)(0). The evolution of arterial lactate concentrations during recovery can ... | 689,008 | [
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0.1860246,
0.01490632,... |
The capacity of polyadenylated RNA from myogenic cells treated with actinomycin D to direct protein synthesis in a cell-free system. | Cytoplasmic polyadenylated RNA of myogenic cells was shown to decay with biphasic kinetics, suggesting the existence of two main populations of mRNA with respect to stability. In the present study, the stability of mRNA extracted from actinomycin-D-treated cultures of a myogenic cell line was tested by its capacity to ... | 689,026 | [
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1.0074,
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0.... |
Regional and central hemodyanamics during segmental ischemia of the small intestine in the rat. | The influence of segmental small intestinal ischemia on the central circulation and on the regional blood flow to consecutive segments of the small intestine in the rat was investigated with the microscphere method. Ischemia was established by ligating 11 arterial mesenteric end arcades, corresponding to one quarter of... | 689,052 | [
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0... |
Accelerated healing of gastric ulcer after removal of the greater omentum in rats. | Standardized ulcers were produced in rats by local application of acetic acid to the serosal surface of the stomach. Ulcers induced at the lesser curvature, the greater curvature or the posterior wall were found to be of similar size after 2 and 4 weeks. In a group of animals the greater omentum was excised just before... | 689,054 | [
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0.2714772,
0.09082793,
0.0161... |
Dynamic ventriculography with K-strophantin. | Dynamic ventriculography, before and after K-strophantin, was performed in 14 patients with coronary artery disease. Qualitative and quantitative evaluation of hemodynamic and angiographic data has been assessed. Digitalis was found to have different action on asynergic areas--that is improvement in some areas and wors... | 689,071 | [
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... |
Suppression of CFU-s activity by rabbit-anti-mouse brain serum can be overcome by treatment with papain. | The suppression of CFU-s activity which is observed after incubation with rabbit-anti-mouse brain sera (RAMB) can be reversed by incubating the antibody coated cells with papain. Papain treatment does not alter the CFU-s membrane since pre-treatment with the enzyme does not protect CFU-s from the lethal effect of RAMB.... | 689,124 | [
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... |
[Modulation of the activity of neurons of Deiter's nucleus upon electric stimulation of the hypothalamus and limbic structures of the brain]. | In immobilized cats, stimulation of the lateral hypothalamus facilitates the activity of vestibular neurons; stimulation of the hypothalamic ventro-medial nucleus and dorsal hippocampus suppresses the unit activity, mainly. The effects of stimulation of the basolateral amygdalar nucleus were excitatory as well as inhib... | 689,200 | [
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0.0821... |
HLA-antigens and psoriasiform napkin dermatitis. | HLA typing was performed in 14 patients with psoriasiform napkin dermatitis (PND). Only 2 patients carried one of the three antigens (HLA-B13, B17, Bw37) associated with psoriasis vulgaris. The frequency of these antigens in PND corresponds to that in healthy controls, but differs significantly (p less than 0.01) from ... | 689,234 | [
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0.08923133,
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[Possible role of protein damage in the development of UV-induced isochromatid breaks]. | The rate of structural chromosome mutations at the second K-mitosis was studied in the primary culture of embryonic fibroblasts from BALB mice, after treating these cells with UV-rays at various wavelength during G2-phase. The action spectrum of UV-rays for chromatid aberrations, determined at 254, 265, 280 and 302 nm,... | 689,368 | [
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[Effect of genotype on the angiotensin-forming system of plasma and the hypothalamus]. | It is shown that hypothalamic renin-like enzyme of mice (lines C57B1/6 and BALB/c) consists of two forms differing from one another in their molecular weight. The allele AY determines the absence of the heavy form of renin-like hypothalamic enzyme (RLHE) and a relatively low level of activity of the blood plasma renin ... | 689,369 | [
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0.1647411,
0.2258922,
0.2752876,
0.228693,
0.1155693,
-0.2255009,
-0... |
Arterial patterns in the hand and pollicisation. | The arterial pattern of the human hand shows remarkable variations in so called normal individuals. In patients with congenital deformities of the hand there are also be variations based on embryonic disturbances. Therefore, the total pattern is complex. Successful transfer of fingers depends on an adequate blood suppl... | 689,497 | [
-0.1591787,
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0.1870585,
0.3461035,
-0.04162377,
... |
Investigations on the fauna of beds in flats, children's sanatoria and old-age homes. | An analysis was carried of the fauna found in 338 beds from two old-age homes and from flats inhabited by asthmatic children. During hospitalization of these children the fauna in the flats was compared with that found in beds used by them in sanatoria. The most abundant species proved to be Dermatophagoides pteronyssi... | 689,564 | [
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0.2275962,
0.08612075,
0.0161918,
-0.1368234,
0.3383445,
-0.1646... |
Study of malpractice panels notes advantages, problems, gaps in data. | A special study on malpractice panel systems in four states identified the currently limited participation of non-physician hospital personnel and 14 factors that determine the effectiveness of such systems. However, more data are needed to determine whether such systems resolve cases fairly and quickly and stabilize m... | 689,621 | [
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0.1039768,
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0.0655... |
Creativity and hospital costs: it's all in the approach. | Although most hospitals do consider costs before deciding to fund a new undertaking, many of them fall short of the necessary inventiveness when it comes to developing low-cost alternatives in problem-solving situations. Thus, too often, solutions to problems are found in a climate of crisis that overshadows considerat... | 689,623 | [
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0.1007058,
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0... |
We only have to ask. | As a group, hospital trustees have great potential for effecting positive change in the hospital industry. Hospital administrators and hospital associations must recognize this potential, focus the commitment trustees are willing to make, and put that commitment to constructive use. Without their help, the author says,... | 689,626 | [
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0.08079337,
0.1284897,
0.01891647,
0.04317169,... |
Hospital administrators face stiff competition in job market. | Career opportunities in health administration will broaden, but the career ladder will be harder to climb, according to the president of the American College of Hospital Administrators. | 689,634 | [
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0.06665833,
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0.1584688,
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0.2488875,
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Group purchasing of food items maintains quality, cuts costs. | Hospital food group purchasing programs face problems that other kinds of group purchasing programs don't have. HARICOMP, a not-for-profit hospital shared services corporation, helped a group of Rhode Island hospitals solve some of these problems by using computers. The computers eliminate much of the time-consuming ef... | 689,639 | [
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-0.008173466,
-0.1471378,
-0.03782289,
0.07699985,
-0.181146,
... |
Human semen as a source of epithelial cells for culture. | When washed cells from human semen samples were plated out, epithelial cultures were obtained. The human ejaculates used as starting material contained, in addition to spermatazoa, 10(3) to 10(7) cells of other types, including granulocytes, macrophages, lymphocytes, spermatocytes and epithelial cells. Although no frac... | 689,703 | [
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0.1066602,
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0.06324781,
0.4302626,
0.269888,
-0.0722689,
... |
Protein synthesis in imaginal disks of Plodia interpunctella during development in vivo and in vitro. | Wing imaginal disks were dissected from larvae of Plodia interpunctella (Hübner) at various stages during the larval-pupal transformation. The wing-disk proteins separated by electrophoresis and scanned with a densitometer changed quantitatively but not qualitatively during development in vivo. Treatment of wing disks ... | 689,708 | [
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0.5514557,
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0.3662737,
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-0.02887285,
-0.05789103,
0.2822004,
0.170862,
0.06250... |
Passive transfer of resistance to frambesial infection in hamsters. | The immune mechanism by which hamsters acquire resistance to infection with Treponema pertenue, the causative agent of frambesia, or yaws, has not been elucidated. Serum or cells (spleen or lymph node) obtained from hamsters resistant to frambesial infection were transferred to normal syngenic recipients, who are subse... | 689,730 | [
0.07098479,
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0.3699469,
-0.04560179,
-0.02698097,
-0.2996... |
Purification of tritium-labeled cholera toxin. | Cholera toxin was labeled with tritium by the Wilzbach technique, and highly purified radiolabeled toxin was obtained by Sephadex column chromatography and disc gel electrophoresis. 3H-labeled cholera toxin retained its biological activity and chemical stability and had a specific activity of 405.9 muCi/mumol. The meth... | 689,738 | [
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0.03102042,
0.423303,
0.2397442,
-0.1427394,
... |
Quantification of EEG variability. | This paper presents a method of segmenting the EEG based on the well-known power spectrum analysis. This procedure is applied to the EEG recordings of two normal subjects in order to determine the temporal EEG variability. These results are compared with a more classical approach. | 689,771 | [
-0.09038058,
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0.3148074,
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0.06838558,
0.164841,
0.1155865,
... |
The use of computers in pharmacokinetics. | A review of computer applications is presented, and several examples of the use of analog and digital computers are given. Special attention is given to fitting the time concentration data to the one, two or more exponential equations, for estimation of pharmacokinetic parameters, for dosage regimen of drugs and for ev... | 689,793 | [
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0.1479578,
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0.1643493,
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0.09711009,
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0.3054112,
0.3516029,
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0.1885315,
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0.2445341,
0.2864038,
0.1778458,
-0.06990574,
-0... |
Liver arginase activity and plasma urea-nitrogen in steers fed diets containing different levels of protein. | Seventeen Charolais-Hereford crossbred steers averaging 220.0 kg in weight initially were randomly allotted to three treatments and fed diets containing (A) 9%, (B) 11%, or (C) 13% protein ad libitum in individual pens for 238 days. Liver samples were taken by aspiration biopsy on days 47 (sampling I) and 238 (sampling... | 689,812 | [
0.02719735,
0.02465824,
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0.3383641,
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0.01492327,
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0.0510949,
0.1226694,
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0.02779095,
0.4432226,
0.02738756,
... |
Experimental closure of urinary bladders with surgical staples. | The auto stapler, an instrument proven to be effective in other surgical procedures, was utilized to close the canine urinary bladder. The procedure was found to be simple. Anticipated postoperative complications, particularly leak, infection, or stone formation were not experienced. | 689,841 | [
0.01857797,
0.02360209,
-0.1420135,
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-0.1903191,
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0.1753329,
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0.3634422,
0.3452849,
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0.1707213,
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-0.598583,
0.1169107,
-0.2064927,
-0.06124521... |
Development of the Multidimensional Health Locus of Control (MHLC) Scales. | The development of the Multidimensional Health Locus of Control scales is described. Scales have been developed to tap beliefs that the source of reinforcements for health-related behaviors is primarily internal, a matter of chance, or under the control of powerful others. These scales are based on earlier work with a ... | 689,890 | [
0.01656674,
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0.06363985,
0.05187023,
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-0.02569952,
-0.04174073,
-0.02652... |
Calcium in isolated mitochondria from the left ventricular wall. | The content of calcium per mg mitochondrial protein has been measured by conventional biochemical methods in myocardial tissue of some mammalian species. In addition, a method is presented for (1) the analysis of mitochondrial volumes in the same tissues and (2) calculating the amount of calcium in units of 10(6) mitoc... | 689,916 | [
-0.4263745,
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0.1184023,
-0.09782391,
0.3369974,
0.4079066,
0.1308897,
0.04937752,
0... |
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