title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Electron probe X-ray microanalysis of human skeletal muscle involved in rheumatoid arthritis. | Electron probe X-ray microanalysis in the scanning microscope was used to determine the elemental composition of muscle fibres from patients with rheumatoid arthritis (RA). Quantitative data concerning phosphorus, sulphur, chlorine and potassium were correlated to the fibre type by a routine method based on serial cryo... | 689,924 | [
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Fleabite allergic dermatitis: a review and survey of 330 cases. | Clinical signs of acute fleabite allergic dermatitis (FAD) in dogs included intense pruritus and erythema. Dogs with chronic FAD had diminished pruritus. The primary lesion of FAD was a papule. Secondary lesions (hyperkeratosis and hyerpigmentation) were common. Diagnosis of FAD was based on history of flea infestation... | 689,971 | [
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The velocity field of growing ear cartilage. | The velocity vector field of the growing rabbit ear cartilage has been investigated between 12 and 299 days. Empirical curves have been computed for path lines and for velocities between 12 and 87 days. The tissue movement has been found to behave as an irrotational flow of material. Stream lines and velocity equipoten... | 689,993 | [
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Inhibition of peptidoglycan biosynthesis at a postcytoplasmic reaction in a stable L-phase variant of Streptococcus faecium. | Cultures of a stable L-phase variant of Streptococcus faecium F24 produced and retained peptidoglycan precursors intracellularly over the entire growth cycle in a chemically defined medium. The identity of the most abundant precursor, UDP N-acetylmuramyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine (UDP-MurNAc-pentap... | 690,080 | [
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Oxygen and nitrate in utilization by Bacillus licheniformis of the arginase and arginine deiminase routes of arginine catabolism and other factors affecting their syntheses. | Bacillus licheniformis has two pathways of arginine catabolism. In well-aerated cultures, the arginase route is present, and levels of catabolic ornithine carbamoyltransferase were low. An arginase pathway-deficient mutant, BL196, failed to grow on arginine as a nitrogen source under these conditions. In anaerobiosis, ... | 690,081 | [
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Cadmium toxicity and liver mitochondria. I. Different effects of cadmium administered in vivo to adult, young, and ethionine-fed rats. | The changes in liver mitochondrial respiratory activities and cytochrome concentrations were investigated when cadmium chloride was administered orally to adult, young, and ethionine-fed rats. Following a seven-day administration of 30 ppm cadmium in drinking water, adult rats showed no change, while young rats and eth... | 690,095 | [
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Prehospital burn care for emergency medical technicians. | The development, objectives, content, and evaluation of a unique, 60-minute synchronized slide/tape program on prehospital burn care for Emergency Medical Technicians is described. A design for valid content-referenced formative evaluation is presented. | 690,106 | [
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Ultrastructure of the proximal region of somatic cilia in Paramecium tetraurelia. | The morphology of the transition zone between the terminal plate of the basal body and the 9 + 2 region of the somatic (non-oral) cilium has been examined in Paramecium tetraurelia. Freeze-fracture and thin-section techniques disclosed both membrane specializations and various internal structural linkages. Freeze-fract... | 690,175 | [
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Biosynthesis of chenodeoxycholic acid in man: stereospecific side-chain hydroxylations of 5beta-cholestane-3alpha,7alpha-diol. | Stereospecific side-chain hydroxylations of 5beta-cholestane-3alpha, 7alpha-diol were studied in mitochondrial and microsomal fractions of human liver. Incubation of 5beta-cholestane-3alpha, 7alpha-diol resulted in hydroxylations at C-12, C-24, C-25, and C-26. Hydroxylations at C-24 and C-26 were accompanied by the int... | 690,184 | [
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The relative accuracy of U.S. British, and Mexican raters in judging the emotional displays of schizophrenic and normal U.S. women. | Asked U.S., British, and Mexican male students of college age to discriminate among three affective displays presented by 10 schizophrenic and 10 normal U.S. women. Significant main effects for diagnostic category, nationality of judge and for the interaction of nationality and diagnostic category were obtained. Furthe... | 690,194 | [
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The relationship between depression and self-concept discrepancy among different generations of Japanese-American women. | Investigated the relationship between real-ideal self-concept discrepancy and depression among different generations and age groups of Japanese-American women in Hawaii. In contrast to the numerous results with Caucasian Ss, the present findings revealed that self-concept discrepancy and depression are related positive... | 690,203 | [
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The measurement of psychological states by use of factors derived from a combination of items from mood and symptom checklists. | The similarities in structure and usage of two widely used adjective checklists, the Profile of Mood States (POMS) and Symptom Checklist (SCL), suggested the feasibility of pooling the items from the two scales into a single factor analysis. This procedure was clinically appealing, statistically sound, and provided an ... | 690,208 | [
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Rorschach suicide predictors: a crossvalidational study. | Attempted to replicate previously reported findings that individuals who commit suicide give a greater number of transparency and cross-sectional responses on the Rorschach than matched nonsuicidal Ss. In addition, a variety of other scoring categories reported in the literature as being more frequent in suicidal Ss we... | 690,222 | [
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Comparison of two alcoholism scales with alcoholics and their wives. | Both partners in 36 alcoholic marriages responded to two different alcoholism scales, the Michigan Alcoholism Screening Test and the MacAndrew Alcoholism Scale. Multiple regression analysis determined that each scale was predicted differentially, but that characteristics of the wives accounted for considerable variance... | 690,229 | [
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Giant lymph node hyperplasia of the mediastinum and refractory anaemia. | An example is described of the syndrome of refractory anaemia in association with the plasma cell variant of giant lymph node hyperplasia of the mediastinum; the anaemia responded to removal of the lymphoid mass. The entity of giant lymph node hyperplasia is discussed and its relationship to the haematological syndrome... | 690,239 | [
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Serum concentrations and inhibitory ratios during amikacin therapy of gram-negative infections. | The ratio of the peak serum concentration after a 500-mg dose of amikacin to the pathogen minimum inhibitory concentration was determined for 95 patients under treatment for serious Gram-negative infections. There were 113 such ratios. The relationship of this inhibitory ratio to the clinical effectiveness and side eff... | 690,253 | [
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Relationship between milk yield and mammary gland development in mice. | Female mice from four lines exhibiting different nursing ability (as measured by mean 12-day weight of eight offspring within a nursed litter) were used to examine milk yield, body size, feed intake, and cellular development of mammary glands and liver. Three selected lines exceeded the control line in milk yield and m... | 690,300 | [
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Radiotherapy of mycosis fungoides: twenty years of experience with teleroentgen and low-voltage X-ray therapy. | Of 98 patients with mycosis fungoides, 55 have been treated with teleroentgen therapy and 43 with low voltage radiation at a shorter distance. Teleroentgen therapy is indicated in the stage of generalized eczematous lesions or superficial infiltration. According to the Hamburg method, a dose of 300 R was delivered to e... | 690,311 | [
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Adverse effects of superficial X-ray therapy and recommendations for safe use in benign dermatoses. | The danger of superficial radiotherapy for benign dermatoses has been exaggerated. It is safe if certain precautions are observed. The permissible life time maximum cumulative dose of conventional superficial X rays generated at 50 kV given to any area of skin is 1000 R, and of grenz rays, 5000 R. | 690,314 | [
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Haemodynamic study of patients with severe sepsis during haemodialysis. | A study was performed in order to observe haemodynamic changes induced by haemodialysis in 14 patients with acute renal failure and severe sepsis. Left ventricular function, as assessed by changes in pulmonary wedge pressure and left ventricular stroke work index through plasma volume expansion, did not change during h... | 690,321 | [
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[Fluorescence histochemistry and neurohistologic studies of the adrenergic innervation of the pyriform cortex in the rat]. | The pyriform region of normal adult rats was investigated by fluorescence histochemistry and Golgi-rapid-impregnation technique. Fluorescence microscopically noradrenaline and dopamine fibers could be described in typical arrangement and distribution. It is suggested that various Golgi-"beaded" -axons in the cortex pyr... | 690,408 | [
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Phylogenetical changes and functional specializations in the dorsal lateral geniculate nucleus (dLGN) of mammals. | Depending on their visual specialization and their place in the zoological system the mammalian species show some peculiarities in the morphology of the dorsal lateral geniculate nucleus (dLGN). The lamination of dLGN can be find in mammals with a highly developed visual system and a proportionally big part of ipsilate... | 690,414 | [
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Studies on the activity of the sympathetic nervous system in essential hypertension. | Plasma catecholamine and norepinephrine concentrations have been measured in carefully characterized ambulatory patients with essential hypertension under basal conditions and following experimental procedures known to enhance sympathetic activity. The studies have demonstrated increased levels of plasma catecholamines... | 690,418 | [
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Idiotypic analysis of anti-GAT antibodies. I. Presence of common idiotypic specificities in both responder and nonresponder mice. | The synthetic terpolymer of L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) induced anti-GAT antibodies in D1.LP mice. Some of these antibodies shared common idiotypic specificities. The interaction between idiotypic antibody and anti-idiotypic antiserum was specifically inhibited by GAT and the closely related polyme... | 690,432 | [
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Structural studies of the H-2D products of the mouse mutant BALB/c-H-2Ddb and the parental strain BALB/cKh-H-2Dd. | The tryptic peptide profile characteristics of the H-2D glycoprotein, isolated by immunoprecipitation from the MHC mutant mouse strain BALB/c-H-2Ddb, were compared with those of the H-2D molecule from the parent strain BALB/cKh-H-2Dd. At each stage of purification these molecules exhibited identical biochemical propert... | 690,440 | [
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Physical forces in blister formation. The role of colloid osmotic pressure and of total osmolality in fluid migration into the rising blister. | The physical forces operative in the fluid migration from the interstitial spaces into the blister cleft have not been directly measured until now. The colloid osmotic pressure and the total osmolality were determined in suction blister fluid after mild suction blister production by a modified "Dermovac" and in blister... | 690,485 | [
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Resolution of desmosterol, cholesterol, and other sterol intermediates by reverse-phase high-pressure liquid chromatography. | A highly efficient technique has been developed for the resolution of several sterols that are intermediates in the biosynthesis of cholesterol and that differ only by one carbon-carbon double bond or by one methyl group. The technique described utilizes reverse-phase high-pressue liquid chromatography on a micronBonda... | 690,514 | [
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Analysis of bile acids in serum and bile by capillary gas-liquid chromatography. | Various liquid phases for glass capillary columns have been evaluated for gas-liquid chromatographic analysis of methyl ester trimethylsilylether derivatives of bile acids from serum and bile. Bile acid analysis is rapid and exhibits high separation efficiency with a 20 X 0.3 mm glass capillary column whose internal su... | 690,516 | [
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Bile acids. OV. 2,2-Dimethoxypropane: an esterifying agent preferred to diazomethane for chenodeoxycholic acid. | Artifacts formed by methylation of chenodeoxycholic acid with diazomethane are identical to the synthetic 3alpha- and 7 alpha-monomethyl ethers of methyl chenodeoxycholate. The extent of formation of these artifacts with time has been studied. No detectable artifacts were found with 2,2-dimethoxypropane as the methylat... | 690,519 | [
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A quantitative technical quality assay method for electrocardiograms. | A method is presented for quantitative assessment of ECG technical quality to permit sensitive detection of performance trends of individual technicians or entire ECG laboratories. The common flaws in ECG recording technic are those which introduce ultra-low frequency artifact or baseline shift, powerline artifact, myo... | 690,553 | [
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Metastatic atrial tumor: case report with electrocardiographic-pathologic correlation. | This report describes a case in which the pre-mortem diagnosis of a right atrial metastasis from a bronchogenic carcinoma was made on the basis of distinctive PR segment (atrial repolarization) changes and atrial arrhythmias. The differential diagnosis of such PR segment deviations also includes functional changes, per... | 690,555 | [
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... |
Polio immunization: benefits and risks. | There are epidemiological as well as legal risks to polio immunization. The physician should compare the risks of vaccination with the risks which attend nonvaccination. Another view of the incidence of paralysis following oral poliovaccine (OPV) shows that the risk is about 1.6 cases per 10(6) nonimmune children given... | 690,580 | [
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A variant of adenovirus 12 producing cytoplasmic accumulation of capsid proteins. | A variant of adenovirus type 12 (R-Ad12) has been isolated by infecting a clonal line of normal rat kidney cells (NRK) with wild-type adenovirus 12. Although R-Ad12 failed to produce infectious progeny virions when cycled a second time through NRK cells, it nevertheless retained the ability to code for virus structural... | 690,616 | [
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Patterns of disorder in first admission psychiatric patients. | Are there patterns of characteristics in psychiatric patients, different from traditional diagnostic considerations, that could provide important information for understanding, treatment, and research? To pursue this question, this report describes an investigation of clinical and demographic characteristics in a repre... | 690,622 | [
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Amobarbital treatment of multiple personality. Use of structured video tape interviews as a basis for intensive psychotherapy. | The case of a 30-year-old woman with five distinct personalities is presented. The patient was treated, using a system of structured video taped sodium amobarbital interviews, in which areas to be explored were developed in psychotherapy. Tapes were played for the patient after each session. The taped material was used... | 690,626 | [
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Membrane-potential-sensitive dyes for optical monitoring of activity in Aplysia neurons. | Two membrane-associated dyes (WW375 and NK2367) which change their absorption of light when the membrane potential changes have been studied using several preparations form Aplysia. Action potentials are easily observed in nerve trunks (from a number of axons), in bag cell clusters, in some of the larger single cells o... | 690,634 | [
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Treatment of myoclonus with pheneturide. | Twenty-one patients with various forms of myoclonus are presented. Phenacemide was given to five patients with considerable benefit to three, but with serious toxic effects in two. Another acetylurea derivative, pheneturide, was given to 19 patients and was well tolerated. Myoclonus was completely or substantially cont... | 690,636 | [
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Electrophysiological appraisal of relative segmental motoneurone pool excitability in flexor and extensor. | F responses recorded from flexor and extensor muscles were analysed in 18 normal subjects and in 16 patients with motor system abnormalities. The prominence of the F responses was evaluated quantitatively by determining the persistence--that is, the fraction of measurable F responses which actually occur after a series... | 690,640 | [
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0.046201,
0.14165... |
Transneuronal changes in the optic tectum following eye enucleation in the newborn rat. | Following unilateral eye enucleation, degenerated neurons were observed in the affected tectum. However, dead cells also were present in the ipsilateral tectum, i.e., on the side which does not receive input from the enucleated eye. Further, the degeneration pattern observed in the experimental animals was similar to t... | 690,669 | [
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0.5853276,
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Fine structure of the rat carotid body transplanted into the anterior chamber of the eye. | Rat carotid bodies transplanted into the anterior chamber of the eye were studied by electron microscopy. Chief and sustentacular cells and a few ganglion cells survived for 3 months and maintained cytological characteristics similar to those in the intact carotid body. The transplant contained many fenestrated capilla... | 690,676 | [
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Occlusion of inferior vena cava--features by radionuclide venography. | Six adults with inferior vena caval obstruction are presented. Three were the results of surgical intervention, two were secondary to large thrombi, and one was due to pressure from a large renal-cell carcinoma and adjacent nodes. All underwent a modified approach of radionuclide venography, using a moderately large vo... | 690,700 | [
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Ga-67 citrate imaging in malignant lymphoma: final report of cooperative group. | In a large cooperative study of Ga-67 uptake in non-Hodgkin's malignant lymphoma, 76% of untreated patients showed positive uptake in one or more lesions. The percentage of known individual lesions seen on scan was significantly lower; thus, negative findings at any one site may have much less significance than positiv... | 690,701 | [
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... |
Comparison of the Anger tomographic scanner and the 15-in. scintillation camera for gallium imaging. | The Anger longitudinal emission multiplane tomoscanner and a 15-in. Anger camera with multipeak spectroscopic capability were compared in a series of 51 patients. The tomoscanner was preferred in 49%, the camera in 12%, and 39% were equivalent. The tomoscanner preference is statistically significant (p less than .025).... | 690,710 | [
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Vitamin B6 biosynthesis and nucleoside effect in the resting cell system of Flavobacterium sp. 238-7. | As one of the attempts to find clues on precursors or intermediates of the vitamin B6 biosynthetic pathway, the resting cell system of Flavobacterium sp. 238-7, a bacterium producing a high amount of the vitamin, was employed. Among various compounds tested as an additive to the reaction mixture, L-glutamate and nucleo... | 690,725 | [
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Stress and success in dentistry. Some personality characteristics of successful dentists. | This article describes a study of relationships between a selected set of personality characteristics, as measured by the 16PF, and the success outcomes of a group of 109 dentists. Results indicate that Factor C (high ego strength), Factor F (liveliness and enthusiasm), Factor H (venturesomeness), Factor Q1 (experiment... | 690,740 | [
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Intracerebellar hematoma in the neonate. | The early diagnosis of posterior fossa hematoma in three term infants by computed tomography is described. The clinical findings included difficult labor and delivery, sudden onset of apnea during the first 24 hours of life, tense bulging fontanel, falling hematocrit, bloody cerebrospinal fluid, and cerebral obtundatio... | 690,773 | [
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... |
Antitumor agents XXX: Evaluation of alpha-methylene-gamma-lactone-containing agents for inhibition of tumor growth, respiration, and nucleic acid synthesis. | Evidence is presented that a number of sesquiterpene lactones isolated from plants and synthesized pyrimidines containing the alpha-methylene-gamma-lactone moiety are potent inhibitors of Walker 256 carcinosarcoma and Ehrlich ascites tumor growth and marginal inhibitors of P-388 lymphocytic leukemia and Lewis lung tumo... | 690,826 | [
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0.4237861,
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0.06220562,
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... |
Lyophilization of sincalide and correlation of headspace relative humidity with product stability. | An optimum freeze-drying cycle was developed for use with industrial equipment in the processing in vials of a product degraded by traces of moisture. The relative humidity of the headspace gas of the vials, which contained only 5 microgram of active ingredient, was monitored by a GC method and was then correlated with... | 690,827 | [
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0.4797551,
0.144484,
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High-performance liquid chromatographic assay of sulfapyridine and acetylsulfapyridine in biological fluids. | A high-pressure liquid chromatographic method for the sensitive, rapid, and specific determination of sulfapyridine and its N-acetyl derivative in plasma and saliva was developed. A cyano-bonded, reversed-phase, high efficiency column was used. The system detected these sulfonamides in serum to 0.25 mg/liter and within... | 690,830 | [
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0.1881404,
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Effect of surfactants on percutaneous absorption of naproxen I: comparisons of rabbit, rat, and human excised skin. | The in vitro skin penetration model using excised skin from rats, rabbits, and humans was examined to evaluate the relative effect of surfactants on percutaneous absorption of naproxen. Differences in the magnitude of the effect of surfactants in promoting percutaneous absorption of naproxen through skins of different ... | 690,833 | [
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Acetylcholine noise in cultured chick myoballs: a voltage clamp analysis. | 1. Large spherical muscle cells were grown in vitro by allowing dissociated chick myoblasts to fuse in suspension culture. 2. Myoball membranes could be adequately voltage clamped even in the face of large inward currents (ca. 100 nA) induced by ACh. 3. The single channel conductance, gamma, estimated from the ratio of... | 690,913 | [
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0.8335058,
0.2784594,
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A transition temperature for acetylcholine channel conductance in chick myoballs. | 1. The temperature dependence of ACh channel conductance (gamma) and channel open time (tau) was determined by analysing ACh induced membrane current fluctuations in voltage clamped chick myoballs. 2. gamma decreased from 25-30 pmho at 37 degrees C to less than 5 phmo at 10 degrees C. An Arrhenius plot of gamma vs. tem... | 690,915 | [
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Changes in pigeon cone photocurrent caused by reduction in extracellular calcium activity. | 1. Photocurrents have been recorded from the red spot of the isolated superfused pigeon retina. The technique used was to record photovoltage gradients and extracellular fluid resistivity in a direction parallel with the long axes of the receptors. 2. Cone and rod responses were identified, and experiments designed so ... | 690,918 | [
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... |
[Comparative study of the activity of medullary respiratory neurones during polypnea triggered by hypothalamic electrical stimulation or by hypothalamic heating (author's transl)]. | We have compared in "encéphale isolé bas" cats the activity of medullary respiratory neurones during polypnea triggered by electrical stimulation (PSt) or by heating (PTh) of the hypothalamus. The medullary respiratory neurones are classified according to:--their anatomical localization (dorsal or ventral respiratory n... | 690,947 | [
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0.164617,
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Memory development in learning disabled children: evidence from nonverbal tasks. | The purpose of the present study was to test the developmental lag hypothesis with learning disabled children on two and three dimensional nonverbal task. Twenty-two learning disabled boys in two age groups of 11 each were tested on a probe memory recall procedure. In contrast to generalization of a developmental lag h... | 690,952 | [
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... |
The occurrence of amphizoic Amebae in domestic animals. | Random examination of domestic animals revealed the frequent presence of free-living amebae in their bodies. In diseased or dead cows, dogs, pigs, rabbits, pigeons, and turkeys 15 strains of amebae were found, belonging to the genera Acanthamoeba (A. polyphaga), Hartmannella (H. vermiformis), and Vahlkampfia (V. avara,... | 690,954 | [
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Binding of Trypanosoma congolense to the walls of small blood vessels. | The mesenteric microvasculature was studied in rats and rabbits infected with Trypanosoma congolense. By examining vessels in the living animals, trypanosomes were observed to adhere to vessel walls by their anterior ends. It was evident from stained preparations of the vessels that the microcirculation contained 4-140... | 690,955 | [
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Fertility studies of complementing genotypes at the albino locus of the mouse. | Mice doubly heterozygous for two radiation-induced lethal alleles at the albino locus (C3H and C6H) show partial complementation: they are viable but runted and sterile. In C3H/C6H females oogenesis and mating are normal, but nearly all of their fetuses, even when genotypically normal (+/C3H or +/C6H), fail to survive ... | 690,964 | [
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Effect of oestrogen on fetal survival in the rabbit. | Pregnant rabbits (Day 18) were treated i.m. for 3 days with 10 microgram oestradiol 17beta/kg. The number of dead fetuses was significantly greater than in the control animals but corpus luteum weight and peripheral progesterone concentrations were not affected. Fetal death was therefore not due to luteolysis. | 690,969 | [
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Detection of cell-mediated immunity to spermatozoa in mice and man by the leucocyte adherence-inhibition test. | A modification of the leucocyte adherence-inhibition test was developed to study cell-mediated immunity to spermatozoa. The test is highly reproducible and requires very low numbers of leucocytes. Deposition of spermatozoa in the genital tract of the female mouse by one normal mating is sufficient to sensitize the fema... | 690,974 | [
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Protein patterns of human uterine flushings collected at various stages of the menstrual cycle. | Uterine flushings and plasma collected from normal, parous women at various stages of the menstrual cycle were subjected to gel electrophoresis. The protein profiles of the flushings differed in many instances from the plasma pattern by the presence of between one and eleven non-plasma proteins. The distribution of the... | 690,982 | [
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Chiasma counts and non-disjunction frequencies in a normal ram and in rams carrying the Massey I (t1) Robertsonian translocation. | Testicular material from a normal ram (54XY), three rams heterozygous (53XYt1) and one ram homozygous (52XYt1t1) for the Massey I (t1) translocation was examined. The autosomal non-disjunction in the normal ram was 2.0% compared to a mean of 6.1% in the heterozygous animals. In the homozygous animal there were adhesion... | 690,984 | [
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Use of dithiothreitol for improved visibility of the F body in human Y-bearing spermatozoa. | Dithiothreitol was used to decondense the nuclear chromatin before staining human spermatozoa with quinacrine for the F body present in Y-bearing spermatozoa. In unseparated fractions and those enriched in X- or Y-bearing spermatozoa, the number of spermatozoa with F bodies increased by 2-9% after dithiothreitol treatm... | 690,991 | [
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Elimination of fetal mice with sporadic malformations by spontaneous resorption in pregnancies of older females. | The frequency of offspring with sporadic spontaneous malformations in A/JKt mice was significantly smaller in litters from older mothers than in litters from younger mothers. Simultaneously the fetal resorption rate was significantly larger in the older group apparently accounted for most, if not all, of the reduced ma... | 690,992 | [
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Diuretic activity of Mannich base derivatives of ethacrynic acid and certain ethacrynic acid analogues. | Various Mannich base derivatives of selected phenoxyacetic acid type diuretics were synthesized and their diuretic potency was evaluated in dogs. It is concluded that the Mannich bases possess little, if any, diuretic activity of their own. Those Mannich bases that do possess diuretic activity undoubtedly do so as a co... | 691,002 | [
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In vitro antiplaque properties of a series of alkyl bis(biguanides). | A series of eight alkyl bis(biguanide) analogues of alexidine, N,N''''-1,6-hexanediyl bis[N'-(2-ethylhexyl)imidodicarbonimidic diamide] (1), was prepared. Five of these analogues constituted a series isolipophilic with 1 but with varying bridge length between biguanide moieties. The compounds were evaluated in vitro fo... | 691,009 | [
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French medical education: years of change. | In the 1960s medical education in France underwent major changes after nearly a quarter-century of efforts by a few leaders. The reforms were supported by students, externs, and interns but generally were opposed by hospital staff and administration and by those in organized medicine. Following student unrest in the la... | 691,027 | [
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Freeze-fracturing of biological material with a new specimen table. | The freeze-fracturing of various biological material is described with the aid of a modified Balzers specimen table. The advantages of this table are easier and faster handling of the specimens and a better thermal contact between the specimen and the cold stage. | 691,041 | [
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The relationship of a monoamine fiber system to a somatosensory tectal projection in the salamander Ambystoma tigrinum. | After hemisection of the spinal cord and medulla oblongata, a projection has been traced to the inner half of the tectal white of the tiger salamander, using Fink-Heimer degeneration staining. By microelectrode recording it was found that the tectal projection forms a topographic somatosensory map of the contralateral ... | 691,065 | [
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Medical student attitudes about quality of care and training of minority persons. | Ninety-five first year medical students agreed that there was differential medical treatment of minority vs majority persons. Implicated reasons for this phenomenon were lack of personal treatment of members of minorities, distrust of medical workers by minority members, and majority perceptions that minority persons a... | 691,081 | [
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Paroxysmal positional vertigo--a study of 255 cases. | The clinical and electronystagmographic findings of 255 patients with paroxysmal positional vertigo are presented. We believe the disorder should be diagnosed on the basis of the history and clinical findings since we did not find any characteristic electronystagmographic findings other than the recording of an actual ... | 691,098 | [
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Adsorption and penetration of enveloped and naked vaccinia virus particles. | The adsorption and penetration of intracellular naked vaccinia virus (INV) and extracellular enveloped vaccinia virus (EEV) were examined. The adsorption kinetics of INV and EEV were similar, but INV adsorption was found to be more sensitive to the adsorption environment than EEV. The PFU-to-particle ratio for the two ... | 691,111 | [
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Polypeptide composition of extracellular enveloped vaccinia virus. | Extracellular enveloped vaccinia (EEV) virus grown in SIRC and in HeLa cells was purified by consecutive equilibrium centrifugations in sucrose and cesium chloride gradients. A higher degree of purity was obtained with virus material prepared in SIRC cells. The polypeptides of purified EEV and INV (intracellular naked ... | 691,112 | [
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Adenovirus core protein synthesis in the absence of viral DNA synthesis late in infection. | The acid extraction of the adenovirus type 5 core proteins V, VII, and pVII (the precursor to VII) from infected cells and the subsequent electrophoresis on a 15% acrylamide-2.5 M urea-0.9 N acetic acid (pH 2.7) gel, revealed that peptide VII has a similar electrophoretic mobility to that of histone H1. The core protei... | 691,113 | [
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... |
Lungworms in coyotes on the Great Plains. | A total of 395 coyotes (Canis latrans) was examined in the field for lungworms (Filaroides osleri and Capillaria aerophila) with 60 trachea and bronchial trees returned to the laboratory for detailed examination. Coyote carcasses were obtained from eight central states (Oklahoma, Colorado, Wyoming, Iowa, South Dakota, ... | 691,122 | [
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... |
Ultrasound aortic measurement and elective aneurysmectomy. | In a study of 53 cases, aneurysm size was measured with the use of preoperative physical examination, lateral abdominal roentgenography, and B-mode aortic ultrasonography for comparison with direct intraoperative measurement during aneurysmectomy. Mean aneurysm diameter on the basis of physical examination overestimate... | 691,216 | [
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Simultaneous determination of circadian rhythms of locomotor activity and body temperature in the rat. | Stimultaneous determination of the circadian rhythms of locomotor activity and body temperature was carried out in the rat. Deep body temperature was monitored continuously using a telemetric device. The circadian rhythm of locomotor activity was characterized by clustering of several bursts of activity during the dark... | 691,862 | [
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Pharmacological studies on experimental nephritic rats (2). Antinephritic effect of various drugs on Masugi's nephritis. | Masugi's nephritis was induced in rats by a single i.v. injection of antikidney serum from rabbits immunized with the homogenate of rat whole kidneys. The antinephritic effect of drugs was evaluated through determination of biochemical parameters such as contents of protein and enzymes excreted into the urine and serum... | 691,867 | [
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0.069... |
[Errors, hazards and complications in treating acute obstruction of the aorta and major arteries of the extremities]. | Errors made at various stages of the treatment of patients with acute thrombosis and embolism of the aorta and major arteries of the extremities were determined from the analysis of 476 clinical observations. Insufficient orientation of physicians in the problems of acute pathologic conditions of the vessels was the ma... | 691,969 | [
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[Studies on the lymph drainage of the eye 5. Quantitative registration of the lymph drainage from the subconjunctival space with a radioactive tracer (author's transl)]. | In 7 rabbits the drainage from the subconjunctival space to the cervical lymph nodes was observed after subconjunctival injection of 99mTc-micro-colloid. Measurements of the activity distribution were made in vivo with an Anger type camera (pho-Gamma-IV Hp, Searle Nuclear Chicago) and in vitro after dissection with a s... | 692,021 | [
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[The best spectacles for vehicle drivers (author's transl)]. | Spectacles worn by vehicle drivers should fulfil the demands set down by DIN 58 216 standards and should furthermore be constructed in such a manner that the binocular field of vision is impaired as little as possible. In this connection, the nasal parts of the frame are particularly important. The external and interna... | 692,030 | [
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[Protein fractions and their enzymatic activity in the rat myocardium after a flight on the Cosmos-690 biosatellite]. | Gamma-irradiation of rats in the ground-based experiment decreased the activity of aspartate aminotransferase of sarcoplasmatic proteins of the myocardium and increased the activity of adenosine triphosphate of myosin of the myocardium 1 and 26 days post-test. Gamma-irradiation of flight rats also reduced the activity ... | 692,062 | [
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0.1144833,
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[Changes in the sugar content in the blood of dogs during 6 years of chronic gamma irradiation]. | The paper presents the results of a many-year investigation of the sugar content in dogs irradiated with total doses of 125, 370, 720, 750, 1130 rad. During the first year the sugar content tended to increase and later to decrease. Irradiated and untreated animals showed different reactions to additional loads (running... | 692,067 | [
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-0.1126255,
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-0.1194745,
-0.1801485,
-0.04847851,
0.1672272,
0.02694022,
-0.1117863,
-0.0004249222,
-0.1906676,
-0.3674372,
-0.2381613,
-0.020099,
0.2713334,
0.1323174,
0.1409772,
0.04042609,
0.09818545,
-0.17067... |
[Effect of endogenous factors on the process of gas bubble formation in the body in decompression]. | Animal experiments were carried out to study the effects of a feeding regimen and diet composition on the intensity of post-decompression bubble formation as well as to establish a correlation between this process and previous decompression, increased and decreased muscle work, and physico-chemical and morphological bl... | 692,073 | [
-0.1006185,
0.261422,
0.06627477,
0.1847386,
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0.01970802,
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0.001580881,
0.2068289,
0.2930891,
0.1881961,
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... |
A comparison of three methods for obtaining articulatory responses. | This study compared speech-sound productions of 18 children with articulation errors obtained with three different speech-sampling methods. The same 20 stimulus words were elicited by each of three sampling methods: (1) Continuous Speech Task, (2) Modeled Continuous Speech Task, and (3) Spontaneous Picture-Naming Task.... | 692,096 | [
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0.01264427,
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0.006275938,
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0.4548074,
0.08357619,
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... |
Preliminary observations on the use of Corynebacterium parvum in patients with primary intracranial tumors: effect on intracranial pressure. | It has been observed that patients with metastatic brain lesions developed neurologic symptoms when given Corynebacterium parvum. To obtain more information in patients with intracranial mass lesions, intracranial pressures (ICP) were measured or observed in six patients undergoing C. parvum therapy. All patients excep... | 692,136 | [
-0.3919152,
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0.06190761,
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0.2868135,
0.03099684,
0.4178485,
0.07... |
Lipogenesis in iron-deficient adult rats. | Iron-deficient (5 ppm Fe) or control (307 ppm Fe) diets were fed ad libitum to female rats for 7 weeks, and then meal-fed for 4 weeks. Body weights, hemoglobin levels, and hematocrits were lower (p less than 0.01) in deficient group (184 +/- 7, 7.1 +/- 0.4, 32.7 +/- 0.6) than in the control group (220 +/- 10, 16.9 +/- ... | 692,295 | [
0.01704358,
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0.2518027,
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0.3935112,
-0.063... |
Uropygial gland alkane diol diesters in the Kn mutation of the domestic chicken. | Uropygial glands from chickens which are known to have the Kn gene secrete qualitatively the same types of alkane diol diesters as the normal domestic chicken. However, there are many significant differences in the mole percent of individual fatty acids and diols within the diester between the two genetic types of chic... | 692,297 | [
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0.2841257,
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0.001473157,
0.2528847,
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0.1930935,
0.1208621,
-0.1713929... |
Dental caries induction in experimental animals by clinical strains of Streptococcus mutans isolated from Japanese children. | Oral implantation and the cariogenic activity of clinical strains of Streptococcus mutans which had been isolated from Japanese children and labeled with streptomycin-resistance were examined in specific pathogen-free Sprague-Dawley rats. All the seven strains tested were easily implanted and persisted during the exper... | 692,465 | [
0.2082924,
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0.3042391,
0.3309634,
0.2043283,
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0.3167032,
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0.2340995,
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0.002963933,
0... |
Computerized food service as a patient support system. | This paper compares an operations support system with an information system in the area of clinical food service. The advantages of a computerized dietary system over a manual system are discussed. A flexible, data-independent information system facilitates inventory and production control and extends the benefits of n... | 692,468 | [
-0.1071646,
0.2640101,
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0.1229402,
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0.1279177,
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... |
[Ureteral obstruction from metastases of a primary intestinal malignoma (author's transl)]. | As of two own cases the authors refer about ureteral obstructions by paraureteral metastases of primary cancer within the intestinum. Diagnostic procedures within the digestive tract are strongly recommended, if within the urogenital region the etiology remains unclear. As often a causal therapy is not possible any mor... | 692,478 | [
-0.1043104,
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0.1192107,
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0.08175065,
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0.04074982,
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0.05320035,
0.0726994... |
Bovine coccidiosis. A review, including field safety studies with decoquinate for prevention. | Decoquinate (Deccox: Hess & Clark) has been demonstrated in in-house and university studies to be an active coccidiostat when fed daily at 0.5 mg/kg body weight during periods of oocyst exposure, or when experience indicates coccidiosis is likely to be a hazard. For prevention, feeding should be continued for at l... | 692,518 | [
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0.1602435,
0.1448305,
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0.4536256,
-0.1320311,... |
The relation of product formulation to absorption of oral theophylline. | To assess the potential for therapeutic problems related to the bioavailability of oral theophylline preparations, we examined the rate and extent of absorption for various formulations in adult volunteers. Absorption of theophylline from a solution or from uncoated tablets was rapid and complete. Three of six sustaine... | 692,577 | [
-0.1985691,
0.09064803,
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0.4058969,
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0.4095064,
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-0.02084125,
-0.4410148,
0.1439718,
0.3378143,
0.222717,
-0.07365457... |
Biochemistry of drugs. XXV. Substances with antineoplastic effect. LXIII. Pharmacokinetics of delta-/2-amino-6-hydroxy-3,4-dihydro-4-oxo-5--pyrimidinyl/valeric acid-14C (Damvar-14C) in experimental animals. | In experiments on H mice and Wistar rats it was found that radioactivity was excreted after subcutaneous injection of Damvar-14C preponderantly in urine, and after oral administration, in faeces. After subcutaneous injection the urinary excretion set on very fast. After subcutaneous injection of Damvar-14C to H mice wi... | 692,802 | [
0.005182661,
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0.4385583,
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0.1527185,
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0.09345601,
0.2110963,
0.2707211,
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0.06943494,
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0.007752996,
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0.1196976,
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0.3479863,
0.4517747,
0.2476791,
-0.2981347,
0.... |
Angiography of the spinal cord after vertebral trauma. | Angiography of the spinal cord after trauma to the spine is reported in 14 new cases with neurological signs. Three types of angiographic signs are demonstrated: (1) arterial interruption of the anterior spinal artery, the ascending branch of the radiculomedullary arteries or the extravertebral arteries; (2) displaceme... | 692,866 | [
-0.1370023,
0.1409721,
-0.1541361,
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-0.3707822,
-0.329336,
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0.2942268,
0.06031629,
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-0.2030757,
0.2163524,
-0.1449935,
-0.2645038,
0.2984386,
0.03328262,
0.09190267... |
[Celioclysis in the treatment of purulent peritonitis]. | The advantages and contraindications associated with peritoneal drainage are discussed. Reference is made to the advantages of drainage combined with continuous coelioclysis in accordance with a personal method, using doxicycline diluted in saline passed into the peritoneal cavity via a small catheter. A personal serie... | 692,891 | [
-0.1872402,
0.04095984,
0.02340752,
-0.008642702,
-0.1724955,
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0.1046629,
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0.02245893,
0.05450387,
0.07940932,
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-0.538531,
-0.006433321,
-0.1365969,
-0.08985801,
0.1978471,
-0.1713331,
0.0... |
[Surgical treatment of carcinoma of the pancreas]. | Personal experience acquired in the use of radical and palliative techniques in the treatment of 18 cases of carcinoma of the pancreas and 1 of carcinoma of the ampulla hepatopancreatica is reported. The results show that duodenocephalo-pancreasectomy is a sound procedure, particularly in the absence of lymph node inva... | 692,898 | [
0.228889,
-0.2555382,
-0.1212949,
-0.1229463,
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-0.4126852,
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0.09277754,
0.3782325,
0.05287655,
0.007368111,
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0.1156669,
0.0745934,
0.3569897,
0.4676426,
-0.02890916,
0.1106,
... |
[Intraoperative peritoneal lavage in generalized acute peritonitis. Experience with 61 cases]. | After wide preface about peritoneal anatomy, pathological, physiology and physiopatology and about the physiopatology of general acute peritonitis, a case records of 61 patients is produced. All the patients were shocked and urgently operated for general acute septic peritonitis and were abundantly washed with a polisa... | 692,922 | [
-0.1252263,
-0.2574847,
-0.2857489,
0.08026227,
-0.1532971,
-0.08923997,
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0.1047357,
0.01029928,
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0.04992699,
0.01653573,
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-0.1871002,
-0.07909568,
0.4140957,
0.2145725,
0.2593676,
-0.244425... |
[Pseudocyst of the pancreas fistulized into the right pleural cavity]. | The development of a pancreatic pseudocyst which fistulized into the right pleural cavity through a lesion in the diaphragm is described. The case is the 2nd in Italian literature and the 5th in the world. The relationships between pancreatic and thoracic pathology are examined, particularly the various ways in which p... | 692,923 | [
-0.1892983,
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0.02682134,
0.05073385,
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0.165455,
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0.2318513,
0.1092917,
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Endorphins in chronic pain. I. Differences in CSF endorphin levels between organic and psychogenic pain syndromes. | A series of 37 patients with chronic pain was investigated with regard to neurologic and psychiatric variables. Twenty of the patients were classified as having mainly organic (= somatogenic) pain syndromes while 17 patients were rather suffering from psychogenic pain syndromes. Samples of lumbar cerebrospinal fluid (C... | 693,070 | [
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0.1995182,
0.1222549,
0.3192429,
-0.01891622,
0.03253777,
-0.118567,
... |
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