title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Laboratory studies of erythrocytic pyruvate kinase deficiency. Pathogenesis of the hemolysis. | Genetic polymorphism exists in erythrocytic pyruvate kinase (PK)-deficient hemolytic anemia, as briefly described. Destruction of erythrocytes varied in extent, but its mechanisms in different PK-deficient polymorphic persons investigated were similar. A paradoxical post-splenectomy reticulocytosis regularly occurred. ... | 696,684 | [
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Phencyclidine identification by thin-layer chromatography. A rapid screening procedure for emergency toxicology. | The clinical manifestations of phencyclidine abuse may include bizarre neuropsychiatric symptoms, which may mimic the untoward reactions of a variety of illicit drugs. Specific diagnosis and therapy depend, primarily, upon consideration of this drug followed by its prompt and accurate identification. A rapid modified t... | 696,688 | [
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Attitudes toward seeking pastoral help in the event of the death of a close friend or relative. | This study examined correlates of seeking help from clergymen in the event of the death of a close friend or relative. Demographic factors and attitudes toward seeking pastoral help in the event of the death of a close friend or relative were examined in 116 subjects. Half the subjects were undergraduates and half were... | 696,702 | [
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Gastric bezoars--spontaneous resolution. | Six cases of gastric phytobezoars were seen on fiberoptic gastroscopy over a period of four years during which time 1,400 gastroscopies were done. Four of these cases showed complete resolution of bezoars on repeat endoscopy during a follow-up period ranging from two weeks to one year. Our experience shows that, in the... | 696,718 | [
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Effect of theophylline on allergen skin tests. | The effect of theophylline on allergen-induced wheal and flare responses of 15 adults with atopy was studied in a double-blind, crossover study. After intradermal skin tests to determine baseline wheal and flare responses, subjects were assigned randomly to consecutive seven-day courses of theophylline 16 mg/kg/day (as... | 696,747 | [
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Effects of imitation training on immediate and delayed imitation by severely retarded children. | Contingent reinforcement was used in training eight severely retarded children who were previously judged to be nonimitative. A yoked control group was given comparable training, but with noncontingent reinforcement. Posttests of imitation of new behavior of a reinforced model showed significant immediate and delayed (... | 696,761 | [
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Comments on the use of the additive factor method with mentally retarded persons: a reply to Silverman. | Maisto and Jerome (1977) reported a choice reaction time (RT) study relating the rate of memory scan to level of intellectual functioning. In this study, slope and intercept values of the RT function were found to be inversely related. Silverman (1978) has raised some concern over the conclusions reached by Maisto and ... | 696,769 | [
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Autistic children: a study of learning characteristics and programming needs. | Learning-acquisition characteristics of six autistic children were studied in order to examine programming needs. Two studies were conducted. Study 1 showed that the first step of a color-cued sequencing task required four times more trials to learn than did the remaining five steps, producing a significant learning-to... | 696,771 | [
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A study of fetal acceleration tests. | The fetal acceleration test (FAT) is a means of assessing uteroplacental integrity by observing fetal heart patterns while being stressed by fetal movement. Of 584 tests performed on high-risk obstetric patients, 176 were done within 1 week prior to delivery. Favorable antepartum FAT results correlated with unremarkabl... | 696,781 | [
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Effects of human maternal venous plasma glucose concentrations on fetal breathing movements. | Human fetal breathing movements were studied following the maternal ingestion of either a 50 Gm. oral glucose load or an equal volume of water in 22 healthy women with uncomplicated pregnancies at 32 to 34 weeks' gestation. The percentage of time spent breathing in fetuses of glucose-treated mothers increased from 23.2... | 696,782 | [
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Professional patient-instructors in the teaching of the pelvic examination. | A class of 100 second-year medical students was randomly divided into two groups for instruction in the techniques of the gynecologic examination. Each group received a lecture and a demonstration film. The control group then had practical instruction on office or clinic patients. The study group was instructed by spec... | 696,787 | [
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Effect of the specific angiotensin antagonist (Sar1) (Ala8) angiotensin II on blood pressure and the renin-angiotensin system in the conscious pregnant ewe and fetus. | A direct relationship was found between maternal diastolic blood pressure and simultaneously measured angiotensin II (All) levels (P less than 0.001) in chronically cannulated pregnant ewes. The infusion of Saralasin to the ewe resulted in a dose-dependent fall in blood pressure (P less than 0.005), the magnitude of wh... | 696,788 | [
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Evaluation of the pneuma-tonometer. | Intraocular pressure in 125 randomly selected patients visiting the eye clinic at the Massachusetts Institute of Technology for routine care was measured with a Goldmann applanation tonometer and a model 30R Pneuma-Tonometer. Pairs of reading were taken with each instrument when possible, and each trace of the Pneuma-T... | 696,797 | [
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Biofeedback training of knee control in the above-knee amputee. | Learning to control a prosthetic knee is a difficult task for the above-knee amputee. A biofeedback training system was designed to help with this problem. The system was found to be useful with several aspects of knee control. Fifteen patients completed a biofeedback training program. Two of these patients did not ben... | 696,810 | [
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Electrical and mechanical effects of molecular variants of CCK on antral smooth muscle. | Intracellular microelectrode and standard organ bath techniques were used to study in vitro the effects of three molecular forms of the peptide cholecystokinin on the electrical and mechanical activities of canine antral circular muscle. Three forms were studied: the carboxyl-terminal octapeptide of cholecystokinin (CC... | 696,826 | [
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Glucocorticoid receptors in the guinea pig. | In cytoplasmic fractions of liver and kidney prepared from adrenalectomized guinea pigs, tritiated dexamethasone ([3H]DM) is bound with a very low affinity (Kd 4 degrees C greater than or equal to 2 X 10(-7) M). By competition studies, the specificity of this binding was shown to be comparable with that for [3H]DM bind... | 696,849 | [
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The pacemaker cell of the sinoatrial node of the rabbit. | Rabbit sinoatrial nodes were isolated and studied in an attempt to determine the cell of origin of the true pacemaker potential. Cells of the sinoatrial node of the rabbit giving rise to the characteristic true pacemaker potential were iontophoretically tagged with lanthanum. The lanthanum appeared within the cytoplasm... | 696,882 | [
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Is modern-day schizophrenic outcome still negative? | To evaluate formulations about more positive outcome in modern-day schizophrenic patients, the authors assessed 132 young patients 2.7 years after hospital discharge. Despite modern treatment techniques, only 14%-17% of the 79 schizophrenic patients in the study group were functioning effectively without relapses; 50% ... | 696,890 | [
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Patient-therapist matching: a research evaluation. | The author tested the predictive power of 10 hypotheses about the personality qualities of therapists that match with those of schizophrenic inpatients to affect therapeutic course. The personality matching traits predicted with significant accuracy the quality of the therapeutic relationship and even the type of overa... | 696,896 | [
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A heritable disorder of lithium transport in erythrocytes of a subpopulation of manic-depressive patients. | The in vivo RBC/plasma Li+ ratio is determined by the equilibrium between Li+ influx (ouabain-sensitive Na+-K+ pump and ouabain-insensitive leakage pathways) and Li+ efflux (phloretin-sensitive Li+-Na+ counterflow). A study of RBC Li+ transport via these pathways showed that a deficiency of Li+-Na+ counterflow was resp... | 696,928 | [
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When the psychotherapist is black. | The authors present a case report of a white neurotic man treated in long-term psychoanalytic therapy by a black woman psychiatrist. The defense mechanism of reversal--the therapist was white in the patient's early dreams--was evident not only in this patient but in several other white patients treated by the black the... | 696,931 | [
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Success or failure: psychotherapeutic considerations for women in conflict. | The authors describe conflicts experienced by women who request therapeutic intervention because of symptoms of depression, anxiety, marital discord, difficulty in asserting themselves, or inability to complete work that would lead to advancement. They discuss the developmentally based difficulties experienced by women... | 696,934 | [
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[Diazepam (valium). Changes in haemodynamics, myocardial oxygen consumption and vascular tone (author's transl)]. | In 30 patients with congenital or acquired heart disease the haemodynamic effects of diazepam (Valium) 0.3 mg/kg were investigated during surgical procedures under neuroleptanalgesia. The following parameters were measured or calculated: Heart rate (HR), arterial pressure (-Part, Psyst, Pdiast), pulmonary artery pressu... | 696,981 | [
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[Histological findings at the aorta ascendens after measurement of blood flow with ultrasonic doppler technique in chronic experiments with rabbits (author's transl)]. | Following implantation of an ultrasonic transducer in the aortic wall of the rabbit, media destructions and pressure necrosis were ascertained when the transducer was fitted closley around the vessel. When the transducer however was fitted widley around the vessel few departures from the normal structure were registere... | 697,051 | [
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Halothane, tracheal compliance and upper-airway mechanoreceptors. | This study was designed to define the effects of halothane on the compliance of the trachea. An isolated in-situ tracheal preparation was studied in 14 mongrel dogs anesthetized with pentobarbital. Compliance of the closed tracheal segment was measured with continuous intraluminal pressure recordings during repeated in... | 697,080 | [
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[Mental deficiency. Definition, epidemiology, etiology (author's transl)]. | In this account, the author replaces this chapter within the field of pediatrics, showing the present importance of the problem. In spite of a definition which is sometimes imprecise, and epidemiological studies which are incomplete and difficult to draw up, the importance of this subject was obvious to those who drew ... | 697,132 | [
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Effect of orally administered ribavirin on experimental feline calicivirus infection in cats. | Ribavirin administered orally at 75 mg/kg/day in 3 divided doses for 10 days, beginning either 1 or 4 days, after aerosol exposure of cats to calicivirus strain 255, failed to have any beneficial effect on the clinical course of the disease or to reduce viral excretion. Indeed, there was enhanced severity of the clinic... | 697,143 | [
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Pathogenicity of equine herpesvirus: in vivo persistence in equine tissue macrophages of herpesviuus type 2 detected in monolayer macrophage cell culture. | Equine macrophages from the mammary glands of a yearling filly and an 18-year-old barren nonlactatind mare formed cell monolayers in continuous cultures. There was absence of viral cytopathic effect (CPE) in early cell culture passages. The cells from the early cell culture passages having no CPE failed to show evidenc... | 697,153 | [
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0.1203238,
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0.... |
Effect of feeding on plasma uric acid levels in snakes. | The effect of feeding on plasma-uric acid concentrations of the snake was studied. The values were monitored in 2 gopher snakes and 2 black rat snakes which were fed mice. Plasma uric acid values in snakes increased after eating and gradually returned to base line with the digestion of the mice. Uric acid concentration... | 697,168 | [
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Oxygen-assisted exercise in chronic obstructive lung disease. The effect on exercise capacity and arterial blood gas tensions. | Twenty-six patients with severe chronic obstructive lung disease exercised on a treadmill while breathing either room air, supplementary compressed air, or O2. Endurance was significantly increased by O2, but there was no improvement in maximal work rate. No relation was found between increased endurance and the degree... | 697,174 | [
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Differential effects of cyclophosphamide and cortisone acetate on bronchoalveolar phagocytic cell populations. | The effects of cyclophosphamide and cortisone acetate on numbers of pulmonary alveolar macrophages (PAM) and on inflammatory response of polymorphonuclear leukocytes to bacterial infection in the lung were studied in guinea pigs. Groups of animals were treated for 7 days with each drug alone or in combination. Bronchoa... | 697,182 | [
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[Obese children. Psychical aspects studied by Rorschach's test (author's transl)]. | A group of obese children comparatively to a control group of normal children using Rorschach's protocols is studied. Quantitatively it doesn't appear significant differences, although a serie of characteristics in obese children (a proportional increase in answer of small detail and human movement, less number of answ... | 697,203 | [
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[Diagnosis and treatment of bronchiolitis (author's transl)]. | In this paper we review the current facts in the diagnosis and treatment of bronchiolitis. Etiological diagnosis,, clinical features and major problems of differential diagnosis are also discussed. A classification of the patients according to the seriousness of the clinical picture is proposed. Proper treatment requir... | 697,208 | [
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[Fast atrial rhythms (author's transl)]. | The authors present their experience on fast atrial rhythms. Fourteen patients were studied in the first three months of life, nine of them having congestive heart failure. The electrophysiological basis of the reentrance tachycardia at A-V junction is discussed. The pharmacological treatment is reviewed, emphasizing t... | 697,213 | [
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Burns of the eyes and eyelids. | One hundred and ten lid and eye burn cases are reviewed in a series of 552 severe body burn cases. The causes, location, handling, and end results of these cases are described. | 697,286 | [
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Repair in acute and chronic ulcers. | The process of ulcer healing is still incompletely understood and the cause of delayed healing in chronic ulcers is unknown. The work described here is concerned with certain aspects of epithelial repair in experimental ulcers--that is, mitotic activity, cell migration, and cell re-establishment with differentiation, u... | 697,296 | [
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Gastrointestinal microecology of BALB/c nude mice. | The aerobic, facultative, and anaerobic microorganisms cultivable from the stomachs, ilea, ceca, and colons of BALB/c athymic (nu/nu) mice (normal and wasting), thymus-implanted normal nude mice, and their heterozygous (nu/+) littermates were investigated. Ninety-one species representing 23 genera of bacteria and yeast... | 697,355 | [
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Fungal contamination and mycotoxin detection of powdered herbal drugs. | Forty-nine powdered herbal drugs were analyzed for their mold profile and for the potential presence of three mycotoxins (aflatoxin, sterigmatocystin, ochratoxin A). Aspergillus and Penicillium species were predominant, but Rhizopus, Mucor, Cladosporium, and Aureobasidium spp. were also found in a few samples. Mycotoxi... | 697,361 | [
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Staphylococcal enterotoxin A: a chromosomal gene product. | Physical and genetic analysis of the plasmid make-up of Staphylococcus aureus strains S6 and FRI-100 has shown that staphylococcal enterotoxin A is a chromosomal gene product. | 697,369 | [
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[P. Metastasis of prostatic carcinoma to the epididymis]. | When reviewing the bibliography of this rare metastatic location of cancer of the prostate gland, we have only been able to compile the observations published by HUMPHREY (1), BROTHERUS (2) and SMITH (3) wo describe cases with the same location and characteristics. All the observations of metastasis in the epididymis o... | 697,409 | [
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[Sonographic study of hydronephrosis]. | The authors present the experience acquired by the Urology Department of "La Paz" Hospital in the sonographic diagnosis of hydronephrosis over a period of one year. In 47 patients, the percentage of successful diagnoses reached 93.7%, including 32 cases with a silent kidney in the intravenous urography. They discuss th... | 697,417 | [
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Effect of selective proximal vagotomy and truncal vagotomy on gastric acid and serum gastrin responses to a meal in duodenal ulcer patients. | To assess the effectiveness of selective proximal vagotomy (SPV) in reducing the acid response to food, we have compared pre- and postoperative gastric acid and serum gastrin responses to a meal in 11 duodenal ulcer patients with intractable pain treated by SPV, with those of seven ulcer patients with gastric outlet ob... | 697,427 | [
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[Tumors of the testicle: various comments of their etiological and evolutive aspects, and therapeutic results in a review of 360 cases]. | Out of a total of 360 cases compiled of testicle tumours obtained from numerous Spanish urologists, the authors analyse their distribution according to the age at the onset, in decades, in the 232 patients in which it became known to them, observing the greatest incidence between 21 and 50 years of age. They then compa... | 697,424 | [
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The nephrotic syndrome in the Sudan with special reference to schistosomal nephropathy. A preliminary morphological study. | The morphology of 68 renal biopsies from the Sudan is analysed. Schistosomal infection was more common among the nephrotic patients than in the average population (32% against less than 1%). In the schistosomal group the high incidence of focal sclerosing glomerulonephritis (28%) and of secondary amyloidosis (38%) was ... | 697,442 | [
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[The diastolic function of the left ventricle. I. The ventricular suction]. | The paper describes the normal and pathological characteristics of left ventricular filling. There are described some of the most sophisticated methods of assessing left ventricular function: The volume-time curve, the rate of change of left ventricular volume (dV/dt) and the pressure-volume loop. It is discussed the p... | 697,454 | [
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[Aldosteronism after hypokalemia in diuretic therapy of systemic arterial hypertension]. | Twenty-two cases with essential arterial hypertension were studied in the final part of a chronic period of treatment with Chlortalidona and in the first 30 days after treatment. Measurements of the following parameters were made: 1) Change in the excretion of urinary aldosterone (aldo). 2) Change in the arterial press... | 697,472 | [
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[Intestinal amebiasis in children II. Evaluation of various diagnostic technics and different therapeutic regimens]. | The diagnostic usefulness of different laboratory tests was evaluated in 20 cases of invasive intestinal amebiasis: the direct coproparasitoscopic exam in mucus obtained by rectoscopy was positive in 90.0 per cent of cases; the same exam done in mucus obtained by the spoon technique was positive in 40.0 per cent. The s... | 697,484 | [
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[Programs and goals of the CMEA Reference Center for Permanent Cell Lines at the Friedrich-Loeffler Institute for Animal Diseases Insel Riems]. | Multilateral economic as well as techno-scientific cooperation is in a process of persistent expansion between the member countries of CMEA. This is the background against which the need for as well as the programme and the scientific, political, and economic importance of a reference centre for permanent cell lines (c... | 697,530 | [
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Activities of types A and B MAO and catechol-o-methyltransferase in blood cells and skin fibroblasts of normal and chronic schizophrenic subjects. | We assayed activities of monoamine oxidase (MAO) type B in blood platelets and type A (and B) in fibroblasts cultured from punch biopsy specimens of skin, as well as of catechol-O-methyltransferase (COMT) in erythrocytes and fibroblasts. Fibroblasts contained moderate amounts of both forms of MAO (types A and B) found ... | 697,538 | [
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[Transient hypothyroidism in 8 low birth weight newborns. Role of topical application of iodine chemicals]. | Very low plasma levels of thyroxine with a parallel decrease in the free thyroxine index were observed in 8 low birth weight infants. The tri-iodo-thyronine levels were slightly but significantly reduced and there was a concommitant increase in thyrotropin concentrations. The abnormalities, which were usually seen betw... | 697,533 | [
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Regional cerebral blood flow in aphasia. | Regional cerebral blood flow (rCBF) was studied in 13 aphasic patients with left hemisphere lesions, using the intracarotid xenon 133 injection method and a 254-detector gamma camera system. The rCBF was measured during rest and during various function tests, including a simple speech test. In motor (nonfluent) aphasia... | 697,602 | [
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0.194... |
Intentional surgical overcorrection of acquired esotropia. | Fifty-eight patients with surgically treated acquired nonaccommodative esotropia were studied retrospectively, to ascertain what immediate surgical result gives the best chance for a postoperative bifoveal fusional result. Of the cases that were initially overcorrected (exodeviations), approximately two thirds were fus... | 697,622 | [
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0.00209921... |
Anaerobic and aerobic bacteriology in head and neck cancer surgery. | A prospective study of wound infections following major head and neck cancer surgery was undertaken to define a rational approach to trials of antibiotic prophylaxis and initial therapy of these infections. Preoperative aerobic cultures were taken from the planned site of skin incision and from the oropharynx. Both aer... | 697,638 | [
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0.0542844,
0.07886553... |
Roentgenography of paranasal sinuses during treatment of nasal polyposis. | Seventeen patients had severe nasal polyposis. Local treatment with beclomethasone dipropionate caused marked reduction in the size of polyps and the nasal obstruction, and the effect continued throughout the treatment period. In all cases roentgenographic examination showed clouding of the nasal cavity and the paranas... | 697,642 | [
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Pheasant susceptibility at different ages to Eastern encephalitis virus from various sources in Massachusetts. | Thirteen isolates of Eastern encephalitis (EE) virus recovered from various hosts in Massachusetts differed significantly in pathogenicity for pheasants, 21 days old or older, inoculated subcutaneously with graded doses of virus. Among the least pathogenic were two isolates from Culiseta melanura mosquitoes, and among ... | 697,655 | [
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... |
Left ventricular volumes and functioning of the reindeer heart. | Left ventricular volumes were measured by cineangiocardiography in 56 sessions on 25 reindeer, together with determinations of arterial pressure and blood oxygen saturation. The heart rate with the animal kept lying on the sternum at rest was 50 b/min, the aortic blood oxygen saturation 94 to 98% and the aortic blood p... | 697,708 | [
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Crystal structures of egg-white lysozyme of hen in acetate-free medium and of lysozyme complexes with N-acetylglucosamine and beta-methyl N-acetylglucosaminide. | The binding of beta-methyl N-acetylglucosaminide (betaMeGlcNAc) to egg-white lysozyme of hen in the tetragonal crystal form was studied by X-ray diffraction techniques to a resolution of 0.25 nm. The binding of the beta-methyl glycoside is almost identical with the binding of beta-N-acetylglucosamine (betaGlcNAc). Real... | 697,738 | [
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Phosphorylation of adenosine monophosphate in the mitochondrial matrix. | The origin of the GTP needed for th phosphorylation of AMP in the mitochondrial matrix was investigated. When short-chain fatty acids are metabolized by hepatocytes, AMP is readily formed within the matrix by the butyryl-CoA ligase (AMP-forming) reaction (EC 6.2.1.2). The rate of matrix AMP formation in rat hepatocytes... | 697,756 | [
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Is a urea cycle present in insects? | 1. The presence of appreciable activity of the urea-cycle enzymes in the tissues of Sarcophaga ruficornis, a carnivorous dipteran insect, all through its life-cycle appears significant in view of their total absence barring arginase (L-arginine ureohydrolase, EC 3.5.3.1) in the phytophagous lepidopteran eri silkwork Ph... | 697,760 | [
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Herpes zoster in patients with systemic lupus erythematosus. | In the context of prospective trials of immunosuppressive drugs in systemic lupus erythematosus (SLE) nephritis, 83 patients were studied with regard to development of herpes zoster. Herpes zoster was found to occur with high frequency (21%) in patients with SLE nephritis treated with immunosuppressive agents. The cour... | 697,950 | [
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[Scintigraphic changes on the liver and spleen in urticaria pigmentosa]. | In 36 patients with mastocytosis pathological changes in liver and spleen were scintigraphically demonstrated. These changes are due to the histologically proven involvement of the reticuloendothelial system. The infiltration of the liver by mast cells was not evident in liver biopsy. | 697,983 | [
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Failure of preoperative C. parvum vaccine to modify secondary disease following excision of two non-immunogenic murine carcinomas. | Sadler and Castro (1976) reported that a single dose of C. parvum vaccine given i.p. or i.v. to mice 4 days before excision of subcutaneous transplants of Lewis lung carcinoma significantly reduced the incidence of lung metastases in the operated mice. In similarly designed experiments, using 2 different carcinomas of ... | 698,036 | [
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Growth of human gliomas in immune-deficient mice: a possible model for pre-clinical therapy studies. | Thirteen gliomas from 55 neurosurgical specimens, derived from 25 adults and 30 children, have been successfully grown as subcutaneous xenografts in immune-deprived or nude mice. Only 2 of the 30 paediatric specimens implanted (6.7%), a medulloblastoma and an astrocytoma Grade III, have grown compared with 11 of the 25... | 698,041 | [
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Epidermal differentiation in normal and growth-retarded infants: studies in two animal models and in human babies. | The influence of prenatal growth retardation on epidermal growth and keratinization was studied in small-for-dates human babies, runt piglets and in rat fetuses subject to maternal protein deprivation. In the human babies and rat fetuses growth retardation was associated with reduced epidermal growth but normal pattern... | 698,102 | [
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Malignant pyoderma. | A patient is described who developed multiple areas of inflammatory pyoderma on the face, leading to extensive ulceration. Repeated investigations failed to demonstrate any specific bacteria or fungus responsible and trials of treatment with various antibiotics proved unsuccessful. Histology revealed a granulomatous ab... | 698,109 | [
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In vivo and in vitro variations of human erythrocyte glutathione peroxidase activity as result of cells ageing, selenium availability and peroxide activation. | Cases showing erythrocyte glutathione peroxidase (GSH-Px) defects have been previously described. Our experiments demonstrate that a number of non genetic factors may influence the GSH-Px activity in human erythrocytes. Selenium administration in vivo was followed in four subjects by elevation in erythrocyte GSH-Px act... | 698,117 | [
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Erythropoiesis and mean red-cell lifespan in normal subjects and in patients with the anaemia of active rheumatoid arthritis. | Recently developed ferrokinetic methods offer a tool to measure effective and ineffective erythropoiesis and mean red-cell lifespan (Ricketts et al, 1975). We have used this tool to investigate erythropoiesis in normal subjects and in patients with the anaemia of active rheumatoid arthritis. In normal subjects the resu... | 698,120 | [
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... |
Acceleration of methaemoglobin reduction by riboflavin in human erythrocytes. | The effect of riboflavin on nitrite treated erythrocytes from normal subjects and patients with hereditary methaemoglobinaemia due to the deficiency of NADH-cytochrome b5 reductase was studied in the presence of glucose, 2-deoxy-D-glucose or lactate. When glucose or 2-deoxy-D-glucose was used as a substrate for these e... | 698,125 | [
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Prevalence of vibration-induced white finger in fluorspar mines in Weardale. | A combined epidemiological and clinical study of vibration-induced white finger (VWF) was carried out involving 115 men in four fluorspar mines. The overall prevalence of VWF was found to be 50% among 42 vibration-exposed subjects, while that of constitutional white finger (CWF) was 5-6% in all men studied. The VWF lat... | 698,134 | [
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Hippuric acid excretion after benzylamine ingestion in man. | The fate of 14C-benzylamine after oral administration as the hydrochloride has been investigated in two male volunteers. Over 98% of the administered radiolabel was excreted in the urine as 14C-hippuric acid within 24 hours. The rate of urinary hippuric acid excretion was extremely rapid, with more than 90% of the dose... | 698,137 | [
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Environmental temperature and choice feeding of the broiler. | 1. Broilers were kept under environmental temperature regimens of 16, 21, 26 or 31 degrees and given, 22--57 d of age, either a complete diet or free-choice of whole wheat and a higher-protein food containing either 252 or 516 g crude protein (nitrogen x 6.25)/kg. 2. Broilers maintained at 16 and 21 degrees consumed fo... | 698,169 | [
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Amino acid requirements of the breeding sow. 2. The dietary lysine requirement of the lactating sow. | 1. Two experiments, involving six lactating Landacre x (Landrace x Large White) sows were undertaken to study the lysine requirement of the lactating sow and to identify the second limiting amino acid by means of interpretation of plasma amino acid and blood urea levels. 2. A basal diet composed mainly of equal amounts... | 698,174 | [
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Molecular basis of reduced albumin synthesis in Morris hepatoma 7777. | The level of albumin mRNA in the normal Buffalo rat liver and Morris hepatoma 7777 was compared by molecular hybridization with albumin complementary DNA (cDNA) and translational assays. Albumin mRNA was found to be 10% of the total rat liver poly(A)-containing RNA population but reduced approximately fourfold in the c... | 698,190 | [
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Binding of glyceraldehyde-3-phosphate dehydrogenase to phospholipid liposomes. | The binding of glyceraldehyde-3-phosphate dehydrogenase prepared from rabbit muscle to phospholipid model membranes (liposomes) as a function of pH, ionic strength, and the influence of the binding on specific activity of the enzyme was studied. The binding decreases the specific activity of the enzyme. The binding was... | 698,206 | [
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Fatty acid requirements and temperature dependence of monooxygenase activity in rat liver microsomes. | The effect of variation in the microsomal membrane fatty acid composition on Arrhenius plot phase transition temperatures for p-nitroanisole O-demethylation and benzo[a]pyrene hydroxylation has been investigated. In liver microsomes from normal-dieted rats, p-nitroanisole O-demethylase activity has a break temperature ... | 698,209 | [
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An exonuclease activity associated with DNA polymerase I of Micrococcus radiodurans. | An exonuclease activity is associated with one of three DNA polymerase in Micrococcus radiodurans. The nuclease activity co-sedimented with its DNA polymerase I of this bacterium on glycerol gradient centrifugation. Both activities show the same optimum pH and heat-inactivation kinetics. This nuclease hydrolyzes prefer... | 698,224 | [
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Glycolipids of a halotolerant, moderately halophilic bacterium. | A 247 000 x g particulate fraction from a moderately halophilic halotolerant bacterium incorporated [14C] glucose added as UDP[14C]glucose and 32P-labeled phosphatidylglycerol into glucosylphosphatidylglycerol. Exogenously added phosphatidylglycerol was available to the enzyme only when dispersed in a detergent, prefer... | 698,236 | [
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Long-chain acyl-CoA synthetase and "outer" carnitine long-chain acyltransferase activities of intact brown adipose tissue mitochondria. | 1. The activities of long-chain acyl-CoA synthetase (acid: CoA ligase (AMP-forming), EC 6.2.1.3) and the "outer" carnitine long-chain acyltransferase (palmitoyl-CoA: L-carnitine O-palmitoyltransferase, EC 2.3.1.21) have been estimated in intact brown adipose tissue mitochondria. The assay of both enzymes is based on a ... | 698,244 | [
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Enzymes catalyzing the hydrolysis of long-chain monoacyglycerols in rat adipose tissue. | Acetone-ether preparations of epididymal fat pads from fasted or fed rats contained two enzymes catalyzing the hydrolysis of long-chain monoacylglycerols. The enzymes were identified as monoacylglycerol lipase (Tornqvist, H. and Belfrage, P., (1976) J. Biol Chem. 251, 813--819) and lipoprotein lipase by their apparent ... | 698,245 | [
0.2346998,
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0.1659027,
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[Quaternary structure of histidine decarboxylase according to small-angle x-ray diffraction and electron microscopic findings]. | The data on small angle X-ray scattering with histidine decarboxilase (HDC) from Micrococcus sp. n. were analysed and a line of succesively improving approximations of the molecule shape was found: by oblate ellipsoid a:b:c = 1:10.63, by continuous cylinder and hollow cylinder with H = 50 A, 2R = 76 A, 2r = 8A. Biochem... | 698,248 | [
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... |
[Role of electrical interference between adjacent portions of the myocardium in the origin of arrhythmias]. | Excitation propagation was studied in the papillary muscle of cat's heart and on a mathematical model of homogenous fibre, considerable inhomogeneity being created in the duration of the action potential (DAP) in the left and right part of the object studied. Gradual changes in DAP were observed during excitation propa... | 698,260 | [
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[Water content in thin films of nucleic acid nitrogen bases. Ultramicroquantitative determination by means of a quartz resonator]. | A method of quartz resonator is proposed for accurate micro- and ultramicroquantitative analysis of water in various biological systems. Sensitivity of this method may be about 10(-9) g. Some advantages and specific applications of quartz resonator are shown by "weighing" water rigidly bound to homogenous dry films of ... | 698,264 | [
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[Relationship between ion channel properties and the structure of the lactone ring of polyene antibiotic molecules]. | Properties of ionic channels created by amphoterecin B, nystatine and mycoheptin in phospholipid--cholesterol bilayer have been compared. Ionic conductivity and selectivity of channels as well as the frequency of transitions between an open state and a closed one depend on lacton ring structure. Appearance of one more ... | 698,265 | [
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0.1147276,
0.0... |
Osmium-labeled polynucleotides: reaction of osmium tetraoxide, with poly-1,N6-ethenoadenylic acid. | Osmium tetraoxide, in the presence of ligands such as pyridine and bipyridine, adds across the etheno bridge of 1,N6-etheno-9-methyladenine and poly-1,N6-ethenoadenylic acid. The Os:P ratio in the labeled polynucleotide was approximately equal to 1 when bipyridine was used as the stabilizing ligand. A similar study wit... | 698,277 | [
-0.05888888,
0.05671693,
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0.004325531,
0.07013241,
0.3570689,
0.1619662,
0.1032462,
-0.129131... |
Structure determination of lipid bilayers. | A method of determining the phases of X-ray reflections from oriented model membrane systems at low resolution is described. The method involves deconvolution and requires that d less than or equal to 2v where v is the width of the head group region within the bilayer and d is the thickness of the bilayer. The method c... | 698,345 | [
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0.2702716,
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... |
Internal cesium alters sodium inactivation in Myxicola. | When Myxicola giant axons are internally dialyzed with Cs+ as the sole cation, the time-course of prepulse inactivation is selectively accelerated compared to its rate with K+ dialysis in the same axons. This decrease in tauph occurs without any change in the magnitude or time-course of INa during step depolarizations ... | 698,349 | [
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0.1315369,
0.3039464,
0.1731884,
0.41979,
0.... |
Temperature effects on gating currents in the squid giant axon. | The effects of temperature (3 degrees-26 degrees C) on the nonlinear components of the displacement current were measured in internally perfused, voltage clamped squid axons. Steps of potential were applied from a holding potential of -70mV (outside ground) to values from -130 to +70mV and either the current or its int... | 698,350 | [
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0.2135085,
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0.1603072,
... |
[Long-term exposure of rats to high concentrations of carbon dioxide]. | The authors studied the isoenzymatic spectrum of lactic dehydrogenase of the myocardium, the frequency of cardiac contractions and ECG during the action of high carbon dioxide concentration, and also the survival of rats depending on the speed of carbon dioxide concentration increase in the atmosphere. Functional chang... | 698,367 | [
-0.05677865,
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0.4389368,
-0.115... |
[Role of vascular thermoreceptors in the mechanism of cold tremor inhibition by oxotremorine, seduxen and phentolamine]. | Intravenous infusion of oxotremorine, seduxene, and phentolamine to cats not only decreased the cold-induced tremor, but also reduced the subcutaneous vein receptor impulses. Diminished activity of the vascular thermoreceptors served as an additional component in the mechanisms of the inhibitory effect of oxotremorine ... | 698,377 | [
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0.6079503,
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0.2370693,
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... |
[Effect of DL-tryptophan on blastomogenesis induced by acrylic plastic]. | Plastic plates implanted subcutaneously to rats induced sarcoma in 11 of 27 animals (40.7%) which survived up to the time of the first tumour appearance (12.3 months). No tumours were revealed at the sites of the plastic powder implantation. Following long-term administration of DL-tryptophan tumours developed around t... | 698,382 | [
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0.07944209,
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0.2690183,
0.105052,
0.5053642,
0.3893287,
-0.2087954,
... |
[Effect of marrow cavity curettage on bone marrow stromal cell precursors]. | Changes in the number of bone marrow stromal precursor cells of guinea pigs after the bone marrow curettage was studied by cloning in monolayer cultures in vitro. About half of the colony-forming units (CEU-F) is extracted during curettage. Later the number of CFU-F in the curetted bone marrow continues to fall, reachi... | 698,383 | [
0.05960145,
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0.2116622,
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0.06805455,
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0.007227046,
0.4552635,
0.4779193,
0.0439993,
-0.0... |
[Morphologic analysis of the specialized cardiomyocytes of the heart conduction system of vagotomized rats]. | The specialized conduction system of the rat heart was studied by light and electron microscopy at various periods following vagotomy. The dynamics of tissue and cellular alterations is described. Variegation of the cellular reactions at all the postdenervation periods for all the conduction system parts and for all ty... | 698,386 | [
0.220107,
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0.02700305,
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0.2415963,
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0.1497474,
0.2479144,
-0.03569707... |
Rabbit anti-mouse brain serum (RAMBS): lack of specific inhibition of late committed erythroid stem cells in culture (CFU-E). | Heterologous antisera to mouse brain tissue have activity against mouse pluripotent hemopoietic stem cells (CFU-S), but not against granuloid/macrophage committed precursor cells (CFU-C). In these studies we show that anti-mouse brain serum raised in a rabbit does not possess specific activity in vitro against late com... | 698,404 | [
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0.3038327,
0.2036209,
0.04541549,
-0.00145... |
Differences in brainstem response latency with age and sex. | Brainstem evoked potentials in response to clicks at 60dB, 70dB and 80dB were recorded from a group of 70 normally hearing subjects. There were 10 subjects (5 male, 5 female) for each of the decades from the second to the eighth. The youngest subject was 14 years, the oldest 79 years. The possibility of there being inc... | 698,440 | [
-0.1646004,
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0.2466671,
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-0.0371848,
0.3106872,
0.4465432,
0.2384702,
0.18... |
Anti-depressant action of caesium chloride and its modification of chlorpromazine toxicity in mice. | 1. Adult male mice were treated with caesium chloride (1.0 mEq/kg, i.p.) once daily for 54 consecutive days before administration of a single dose or reserpine (2.0 mg/kg) or (+)-amphetamine (1.0 mg/kg). Pretreatment with caesium chloride resulted in potentiation of amphetamine-produced enhancement of motility and in a... | 698,485 | [
-0.4477531,
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-0.1021989,
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0.138182,
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0.2876232,
-0.2011129,
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0.2712477,
... |
Brain specific benzodiazepine receptors. | Brain membranes from rat and human contain a single class of brain specific binding sites for pharmacologically and clinically active benzodiazepines. There is good correlation between the pharmacological effects of benzodiazepines and the affinity for the 3H-diazepam binding site. Benzodiazepine binding sites are not ... | 698,493 | [
0.05675344,
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0.2510445,
0.02978185,
0.1945484,
0.1715156,
0.2543147,
-0.006079629,
... |
The relationship between the rate of gastric emptying and the dumping syndrome. | Following an oral hypertonic glucose challenge, gastric emptying and changes in plasma volume were measured in 15 subjects before and in 36 subjects after a truncal or selective vagotomy with a drainage procedure. The symptoms experienced during the test were noted, and the postoperative patients divided into two group... | 698,537 | [
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0.1243829,
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0.1056778,
0.2292073,... |
Diets and stoma function. | Fifty ileostomy and 50 colostomy patients were questioned as to which foods upset their stoma function. Most patients had no problem in finding a suitable diet and 70 per cent would eat any food on occasions, although half the patients found that side effects with particular foods were a nuisance. Only a small range of... | 698,538 | [
0.002539853,
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0.1308188,
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0.04238755,
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0.1851297,
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-0.07348654,
-0.04783688,
0.2698776,
0.1496... |
A glucose-controlled insulin infusion system for diabetic women during labour. | A glucose-controlled insulin infusion system was used to control blood glucose concentration during labour or caesarean section in six insulin-dependent diabetics. The mean blood glucose concentration during the four hours of labour immediately before delivery was 4.6-5.2 mmol/1 (82.9-93.7 mg/100 ml). Feedback control ... | 698,607 | [
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0.3243204,
0.167035,
0.104994... |
Is nasogastric suction necessary in acute pancreatitis? | Fifty-eight patients with mild to moderately severe acute pancreatitis were randomly allocated to treatment with or without nasogastric suction (27 and 31 patients respectively). Intravenous fluids and pethidine hydrochloride were also given. The two groups were comparable clinically at the start of the study. There we... | 698,650 | [
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-0.01281737,
0.03356025,
-0.02626953,
-0.03060961,
0.07602857,
-0.09023593,
-0... |
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