title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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[Random immunoglobulin. I. Use of chaotropicions and fluorescence quenching for quantitating the non-specific adsorption in the interaction of human IgG with rhodamine B]. | It is shown that, when excited in the visible range, fluorescence of the dye may be either quenched or enhanced, from its initial value Fo, by addition of increasing "normal" immunoglobulin (IgGH7 S), depending if the solution is "non-chaotropic " (NaF 0,1 M) or "chaotropic" KI 1 M). Let F be the fluorescence obtained ... | 776,065 | [
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[Pharmacokinetic characteristics and the chemotherapeutic effectiveness of a 2% ditetracycline-erythromycin eye ointment]. | The study of the antibacterial activity of ditetracycline combination with erythromycin (ratio 1 : 1) showed that the effect of the antibiotics increased with respect to most of Staphylococcus and Coli bacteria. The chemotherapeutic effect of the ointment in treatment of experimental staphylococcal conjunctivitis of ra... | 776,076 | [
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[Study of the mechanism of action of minocycline and of certain other tetracycline group compounds]. | It was shown that the mechanism of action of minocycline on intact cells of E. coli was similar to that of oxytetracycline, i.e. specific inhibition of protein synthesis. In acellular systems of synthesis of polyphenylalanine with ribosomes from tetracycline sensitive and resistant strains of E. coli, minocycline and o... | 776,077 | [
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Promotion of sporulation by caffeine pretreatment in Saccharomyces cerevisiae. II. Changes in ribonuclease activity during sporulation. | Changes in RNase activity during sporulation of a homothallic diploid strain of Saccharomyces cerevisiae were measured in caffeine-treated and non-treated cells. 1. In caffeine-treated cells soon after the transfer to the sporulation medium a significant increase in RNase activity was observed; in control cells the ris... | 776,113 | [
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[New classification of tumor lesions of the hematopoietic and lymphatic tissues and use of these classifications in prosector practice]. | The author presents a review of the world medical literature reports on the latest classifications of tumours of the hemopoietic and lymphatic tissues, based on new concepts of the hemopoiesis system. Changes in the interpretation of the meaning of such terms as "reticular cell", "reticulosis", reticulosarcoma", "hemoc... | 776,147 | [
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The extraction and purification of a cysteine transfer ribonucleic acid from baker's yeast. | 1. A modification of the RPC 1 system of A.D. Kelmers, G.D. Novelli & M.P. Stulberg (1965) (J. Biol. Chem. 240, 3979-3983) is described in which the support medium is a Celite of narrow range particle size treated with dichlorodimethylsilane. 2. By using this system an apparently pure preparation of tRNA Cys was is... | 776,175 | [
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Ligation of patent ductus arteriosus in premature infants. | Twenty-four neonates at 25-34 weeks' gestation with a weight range of 570-1530 g underwent ligation of patent ductus arteriosus (PDA). The infants had mild to severe respiratory distress syndrome at birth and later developed signs of heart failure as a result of left-to-right shunting through a PDA. Surgical closure of... | 776,196 | [
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Subanaesthetic dosage of Althesin as a sedative for conservative dentistry. A controlled trial. | A randomized partial cross-over clinical trial of two intravenous techniques for outpatient conservative dentistry was performed in 61 patients. Subanaesthetic incremental doses of Althesin were used at 52 sessions and a single sedative dose of diazepam at 45 sessions. Each technique produced similar cardiovascular and... | 776,197 | [
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Control of ribonucleic acid synthesis in eukaryotes. 2. The effect of protein synthesis on the activities of nuclear and total DNA-dependent RNA polymerase in yeast. | A thermosensitive conditional yeast mutant (ts-187) which suppresses protein synthesis at the nonpermissive temperature (36 degrees C) also suppresses RNA synthesis. The effect of temperature on the mutant is similar to the addition of cycloheximide--it inhibits the incorporation of labeled precursors into RNA in both ... | 776,213 | [
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Fructose 1,6-bisphosphate: isomeric composition, kinetics, and substrate specificity for the aldolases. | 13C NMR shows fructose 6-phosphate and fructose 1,6-bisphosphate to contain respectively 4.1 and 2.0% keto isomer at room temperature. The lower value for fructose 1,6-bisphosphate can be attributed to the electron-withdrawing effect of the C-1 phosphate. Measurements of the ring-opening rates of the alpha and beta ano... | 776,219 | [
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[Modification of the method of extracting DNA-polymerase from E. coli]. | Described earlier method of isolation of E. coli DNA-polymerase is modified. In order to decrease the possible effect of proteases on DNA-polymerase, the time of autolysis was shortened. An additional stage of precipitation by ammonium sulfate of 65-80% of saturation was introduced. Chromatography on DEAE-Sephadex A-25... | 776,235 | [
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Relationship between Hassall's corpuscles and thymocytes fate in guinea-pig foetus. | The development and structure of the Hassall's corpuscles are studied with the light and electron microscope in 53 guinea-pig foetuses from 30 to 58 days gestation. The different stages of their life cycle are described. Prior to the appearance of Hassall's corpuscles, no medullary lymphocytes can be found in the early... | 776,243 | [
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[Correlation between cytotoxic lymphocytes and cells that synthesize the macrophage migration inhibitory factor in the H-2 system]. | High immunological specificity of the direct and indirect macrophage migration inhibition tests was demonstrated in the H-2 system. The capacity of immune lymphocytes for the MIF production was revealed under their incubation with splenic cells of the congenic or recombinant strains of mice sharing particular private o... | 776,251 | [
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An experiment in teaching MEDLINE. | The design and implementation of an experimental MEDLINE module at Case Western Reserve University School of Library Science is described. The module places MEDLINE within the context of multiple data bases and networking operations andis embedded in a course in health science communications. The module consists of eig... | 776,284 | [
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Reconstruction of the central mandible with a single block of iliac bone. | A reconstruction of the central mandible is described using a single carved segment of iliac bone. The design of the graft takes into account the forces acting upon the remaining mandibular remnants and the need to provide absolutely rigid fixation until bony union is achieved. | 776,310 | [
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A quantitative assessment of femoral head activity using 99Tcm -polyphosphate and a computer data collection system. | Abnormal femoral head activity in Legg-Calve-Perthes' disease has been measured using 99Tcm -polyphosphate and a gamma camera/computer data collection system. A reference point on the data matrix, which is unaffected by the diease, is used for deriving comparative uptake ratios in each femoral head. The reference point... | 776,319 | [
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Effect of plastic skin and wound drapes on the density of bacteria in operation wounds. | Operation wounds were sampled quantitatively by the velvet pad rinse technique to determine the effect of impervious plastic skin and wound drapes on the density of bacteria. A controlled trial (clean operations) revealed no significant difference between the bacterial density of herniotomy wounds for which the skin ha... | 776,325 | [
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Talampicillin: a new derivative of ampicillin. | Talampicillin is a thiazolide carboxylic ester of ampicillin and is hydrolysed in the intestinal mucosa to release free ampicillin. The mean peak serum concentration of ampicillin occurred one hour after a dose of talampicillin and was about twice that attained by an equivalent dose of ampicillin. The presence of food ... | 776,328 | [
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HLA-linked genes and islet-cell antibodies in diabetes mellitus. | In a random series of 139 insulin-dependent diabetics aged 30 or under at the onset of disease islet-cell antibody (ICA) was detected in 33 cases (24%). In 27 patients who had had diabetes for less than one year 16 (59%) had ICA. Only one out of 51 patients with maturity onset diabetes who were not dependent on insulin... | 776,343 | [
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Assessment of a test of renal viability. | A test of renal viability using the uptake of 125I-iodohippurate by kidney biopsy specimens has been developed. It is applicable to all kidneys irrespective of the method of storage. The uptake of 125I-iodohippurate in experimental kidneys correlated well with warm or cold ischaemia time and subsequent renal function. ... | 776,347 | [
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Overview of tumor immunology in gynecologic oncology. | Highlights of recent advances in the field of gynecologic tumor immunology are presented in an effort to demonstrate that at least some cancers of the female genitalia evoke an immune response that can be quantitated in the laboratory. The overview will discuss investigations into the various in vitro assays of both hu... | 776,391 | [
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Radioimmunoassay of antibiotics and chemotherapeutic agents. | Theapeutic monitoring of drugs has become of major importance and has stimulated development of new assay systems. Chemotherapeutic agents, many of which are toxic, have until recently been assayed by microbiological systems or other complex techniques that are impractical for a clinical laboratory. Radioimmunoassays h... | 776,448 | [
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Pharmacokinetic interpretation of data gathered during therapeutic drug monitoring. | We review some pharmacokinetic principles that can facilitate interpretation of data obtained during therapeutic drug monitoring: the one- and two-compartment models, volume of drug distribution, drug clearance, organ clearance, bioavailability, first-pass effect, chronic or repetitive dosing, and use of urine and sali... | 776,451 | [
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Fluid and electrolyte metabolism in the newborn infant. | This chapter has sought to gather together the background information on systems controlling homoeostasis of salt and water and their clinical derangement. The temptation to adopt an all-embracing approach to the management of these problems is strong but such an approach is difficult to achieve and indeed dangerous. T... | 776,460 | [
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Repair of the spondylolisthetic defect and intertransverse fusion for young patients. | A technique, applicable to young patients with mild to moderate symptoms from a pars defect is described. It is based on the concept that bone grafting of the pseudoarthrosis and an intertransverse fusion using small fesh autogenous concellous grafts from the ilium will prevent further slip. Gratifying results have bee... | 776,482 | [
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Renal tubular acidosis: practical guides to diagnosis and treatment. | The syndrome of renal tubular acidosis in some one of its various forms should be suspected when an infant or child has failure to thrive, metabolic acidosis, constipation, diarrhea, vomiting, anorexia, polyuria, or dehydration in infancy. Confirmatory biochemical findings include an inappropriately high urinary pH, in... | 776,486 | [
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The value of the study of the psychopathology of expression. | The study of the psychopathology of expression deals with abnormal tendencies and themes in paintings and creative products of mental and other patients, and the same kinds of themes in the work of normal artists. Its values are as follows: for diagnosis in revealing patients' problems through observation of deviations... | 776,525 | [
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Radiographic findings in aneurysms of the aorta. | The use of specific radiographic criteria in the investigation of an aneurysm of the aorta will enable the physician to determine its etiology with a high degree of accuracy. The etiology, location, type, and extent of an aneurysm determine the proper mode of therapy. Aortography, therefore, is the single most importan... | 776,531 | [
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0.1661553,
0.2626803,
0.03098776,
-0.0468019,... |
Comparison of the acceleration and velocity of shortening of the ventricular radius. Their potential applicability of noninvasive measurements of ventricular performance. | The maximal rate and maximal acceleration of shortening of the radius of the minor axis of the ventricle were correlated with various indices of ventricular performance in 20 patients with angina. The maximal acceleration of shortening showed a closer correlation with the ejection fraction, rate of change of flow, and ... | 776,546 | [
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Structural properties of Escherichia coli RNA polymerase Subunits. | 1. The surface of the RNA-polymerase-DNA complex possesses an exposed polypeptide loop. 2. Proteinases with differing specificities (trypsin, chymotrypsin, subtilisin and clostripain) preferentially cleave the exposed region. 3. The cleaved polypeptide is reassembled into RNA polymerase by renaturation from a solvent w... | 776,611 | [
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Nanosecond pulse fluorometry in polarized light of dansyl-L-cysteine linked to a unique SH group of F-actin; the influence of regulatory proteins and myosin moiety. | The order of magnitude of the correlation time, which characterizes the dansyl cysteine residue linked to F-actin is ten times greater than the correlation time of the G-actin monomer [1]. Still it is much smaller than the correlation times of the F-actin polymer as a whole. The dansyl chromophore reveals that the C te... | 776,673 | [
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The use of sodium valproate in a case of status epilepticus. | A child in status epilepticus, who did not respond to intravenous diazepam, was treated with sodium valproate by naso-gastric tube. Subsequent clinical and encephalographic improvement appeared to be related to the sodium valproate, and its value in cases of status epilepticus is discussed. | 776,731 | [
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[The pre-morbid personality of schizophrenics in the literature of the last hundred years (author's transl)]. | A survey of the literature on the primary personality of schizophrenics shows that the essential concepts derive from Kraepelin (1893), E. Bleuler (who also introduced the technical term "schizoid", 1911) and C.G. Jung introversion; 1913). E Kretschmer (1921) adopted these preliminary findings and integrated them into ... | 776,762 | [
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Strain-related differences in immunosuppressive effects of Enterobacteriaceae and their lipopolysaccharides on production in rabbits of antibody to enterobacterial common antigen. | Certain polysaccharides have been shown to inhibit the antibody response of rabbits to the common enterobacterial antigen (CA). The present investigation revealed that striking differences exist in the immunosuppressive effects of enteric bacteria and their lipolysaccharides (lps), depending upon CA production by the s... | 776,827 | [
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Colonization of porcine small intestine by Escherichia coli: ileal colonization and adhesion by pig enteropathogens that lack K88 antigen and by some acapsular mutants. | Seven K88-negative porcine enteropathogenic Escherichia coli, representing three different serogroups, caused severe diarrhea and characteristically colonized the ileum, but not the jejunum, of intragastrically exposed newborn pigs. Bacterial counts of intestinal contents and wall, fluorescence, and scanning electron m... | 776,834 | [
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Cellular and humoral immune response to guinea pig infected with Treponema pallidum. | Guinea pigs infected intradermally with Treponema pallidum Nichols strain were examined for the presence of lesions and for cellular and humoral response. Of the 26 guinea pigs (77%) demonstrated darkfield positive lesions between 6 and 20 days after infection. Animals divided into six groups of 4-5 in each were sacrif... | 776,839 | [
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A histopathologic study of striated muscle biopsies in leprosy. | Histopathologic changes in striated muscle biopsies in 50 cases of leprosy were studied; 40 being the lepromatous type and 10 the nonlepromatous type. All the biopsies were obtained from midportions of normal looking biceps muscles and paraffin embedded. Sections cut in transverse and longitudinal planes were stained b... | 776,842 | [
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Identification of the major penicillin-binding proteins of Escherichia coli as D-alanine carboxypeptidase IA. | Penicillin-binding proteins 5 and 6 of Escherichia coli have been identified as d-alanine carboxypeptidase IA. | 776,946 | [
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Interaction of bacterial initiation factor 2 with initiator tRNA. | Interaction of bacterial polypeptide chain initiation factor 2 (IF-2) with Escherichia coli formylmethionyl-tRNA in the absence of free Mg2+ renders the fMet-tRNA adsorable to nitrocellulose membrane filters. This reaction does not require GTP and is strongly inhibited by low concentration (1 mM) of Mg2+ in the reactio... | 776,966 | [
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Solitary unicameral bone cyst: treatment with freeze-dried crushed cortical-bone allograft. A review of one hundred and forty-four cases. | One hundred and forty-four solitary bone cysts were treated by curettage and packing with freeze-dried crushed cortical-bone allograft. One hundred and eight healed primarily. There was a higher rate of recurrence in young patients (less than ten years old), in active cysts, in females, and in incompletely packed cysts... | 777,005 | [
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Posterior bone-grafting for infected ununited fracture of the tibia. | Twenty-three patients with severe open tibial fractures complicated by established deep infection and delay or failure of union were treated with posterior tibial bone-grafting. This was followed by immediate ambulation in a plaster cast. Tibial union was achieved in all twenty-three patients. Drainage ceased prior to ... | 777,006 | [
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Restoration of muscle balance of the foot by transfer of the tibialis posterior. | A new technique of tibialis posterior transfer is described which has been used in a wide variety of conditions producing muscular imbalance in the foot. The results in eighty-five feet are reviewed in terms of range of motion, power and voluntary control of the transfer. The effect of the transfer on shoe wear, on the... | 777,009 | [
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0.15... |
Disturbed islet-cell function related to endogenous gastrin release. Studies on insulin secretion and glucose tolerance in pernicious anemia. | The insulin and gastrin response to oral glucose, intravenous glucose, or a protein-rich meal were measured in 44 nondiabetic patients with pernicious anemia (PA) and in 44 control subjects. 36 of the PA-patients had hypergastrinemia, while serum gastrin concentrations in the remaining eight patients were below normal.... | 777,030 | [
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-0.0... |
A comparison of two commerical methods for the identification of the Enterobacteriaceae--API 20E and the Enterotube--with conventional methods. | The API 20E, the Enterotube, and routine methods of Cowan and Steel were used in parallel to identify 245 members of the Enterobacteriaceae. The API 20E and conventional methods gave the same identification in all but 2 (0-8%) of the 245 organisms tested. The Enterotube correctly identified 85% of these organisms on th... | 777,035 | [
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0.03069732,
0.3333959,
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0.067422... |
A new serotyping method for Klebsiella species: development of the technique. | A new serotyping method for Klebsiella species using indirect immunofluorescence is described. Nonspecific fluorescence has been minimized by carrying out the capsular antigen-antibody reaction at pH 9.0. Commercial antisera have been tested with the 72 antigenic types of Klebsiella, and appropriate dilutions of each p... | 777,042 | [
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0.2699754,
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0.191983... |
Classification of smooth muscle autoantibodies detected by immunofluorescence. | Three hundred and twelve sera containing antibodies to smooth muscle (SMA) wer analysed for the immunofluorescence patterns they produced in various tissues. A classification is described based on the three main appearances in rat kidney. Some sera, mainly of low titre, reacted only with vessel walls (SMA-V), some stai... | 777,046 | [
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Intraoral cancellous bone autografts in the treatment of infrabony pockets. | One hundred infrabony pockets with one- and two-wall bony defects were treated for reattachment. Mucoperiosteal flaps were raised, the tooth surfaces were scaled and planed, and the defects curetted. Flaps were sutured tightly and the sites protected with a surgical dressing. Antibiotic coverage was used in each case. ... | 777,049 | [
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0.3691092,
0.1221051,
0.2593389,
... |
Health maintenance organizations: are they for the inner cities? | Health Maintenance Organizations present some major limitations as a means to address the health care needs in our nation's inner cities. The HMO as it has been affected by HMO legislation is discussed and an identification made of those areas that may adversely affect the delivery of health services to inner-city resi... | 777,051 | [
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... |
Visualization of type I and II collagens in tissue sections by immunohistologic techniques. | Rabbit and rat antibodies were prepared against Type I and II collagens derived from bovine skin and articular cartilage, respectively. As judged by passive hemagglutination and radioimmune assays, these antibodies could be rendered generally specific for the type of collagen used for immunization by immunoadsorption. ... | 778,266 | [
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Detection of anti-TNP antibody-forming cells (AFC) with TNP-enzyme and TNP-Fab anti-enzyme conjugates. | Peroxidase (PO), alkaline phosphatase, and glucose oxidase, as well as Fab anti-PO, were coupled with varying molar ratios of trinitrophenyl (TNP) hapten. These reagents were evaluated for their ability to detect anti-TNP antibodies in the lymph node cells of Balb/c mice immunized with heavily-substituted TNP45 alkalin... | 778,269 | [
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Defective leukotaxis in patients with lepromatous leprosy. | Serums from patients with lepromatous leprosy show a high incidence of a chemotactic inhibitor. This inhibitor acts directly on leukotactic factors (bacterial chemotactic factor, C3 fragment, and C5 fragment) to render the factors irreversibly inactive. Functionally, the inhibitor acts as a chemotactic factor inactivat... | 778,311 | [
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0.1751812,
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Human B-lymphocyte antigens expressed by lymphocytic and myelocytic leukemia cells. I. Detection by rabbit antisera. | A previously uncharacterized human B-lymphocyte antigen has been detected by rabbit antisera raised to papain digests of spleen cell membranes. The unabsorbed sera reacted in both cytotoxicity and immunofluorescent tests with normal B lymphocytes and cultured B-cell lines but not with normal T lymphocytes or cultured T... | 778,323 | [
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0.2915463,
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0.02027127,
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Morphological changes in indefinitely surviving enhanced ectopic rat cardiac allografts. | The histological changes of ectopic cardiac allografts in rats have been studied. These consisted of (a) a diffuse chronic inflammatory cell infiltrate of the myocardial interstitium accompanied by variable degrees of fibrosis (b) variable degrees of intimal hyperplasia of the coronary arteries with segmental disruptio... | 778,359 | [
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... |
Enterotoxigenicity and invasive capacity of "enteropathogenic" serotypes of Escherichia coli. | Forty-two strains of Escherichia coli that agglutinated in pools of antisera used to identify "enteropathogenic" serotypes were tested for heat-labile and heat-stable toxin production and for their ability to invade intestinal mucosa. None of the strains tested were enterotoxigenic or enteroinvasive as determined by th... | 778,368 | [
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Measuring periodontal disease in ancient populations: root and wear indices in study of American Indian skulls. | As an example of the collaboration of periodontologists and physical anthropologists, the skulls of two Indian populations were studied. A root index to assay periodontal disease and a wear index to evaluate occlusal wear, were developed. The first Indian population, living 400 years ago, had more decay, loss of teeth ... | 778,374 | [
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... |
Studies on the origin of the alpha-haemolysin produced by Escherichia coli. | Synthesis of alpha-haemolysin by Escherichia coli was proportional to the amount of meat-broth factor present in the medium and not to bacterial growth. The meat-broth component required for the synthesis of haemolysin was found to have several physical and chemical properties in common with alpha-haemolysin itself. Bo... | 778,389 | [
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Studies on the properties of a streptococcal preparation OK-432 (NSC-B116209) as an immunopotentiator. I. Activation of serum complement components and peritoneal exudate cells by group A streptococcus. | The inhibition of transplanted tumors in animals, which were previously injected with a streptococcal preparation, OK-432, has been suggestible to be induced by direct or host mediated effects. In this paper, it was examined of immunopotentiating ability of Group A streptococcus (Su-strain), which is a active component... | 778,447 | [
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Auditing the quality of care in emergency departments. | A methodology for evaluating the quality of emergency department care in the form of a retrospective process audit for emergent and urgent cases was developed and tested in the Philadelphia General Hospital Emergency Department. A physician panel develped criteria against which the management of six "chief complaints,"... | 778,455 | [
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[Clinical and pharmacokinetic researches of doxycyclin vibravenös in childhood (author's transl)]. | Doxycyclin is one of the first efficacious depot antibiotics. It is used in two applications as Vibramycin (R) (peroral and Vibravenös (R) (parenteral). Doxycyclin has a favourable effect not only on different gram-positive and gram-negative bacteria but also on a lot of other germs as mycoplasms, rickettsias, protozoo... | 778,479 | [
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The role of cell membrane in the antiviral effect of interferon. | The mechanism of interferon action in human fibroblasts has been studied by use of both antisera to human fibroblast interferon and the antisera to the surface of human fibroblast cell. The anti-interferon serum completely neutralized the antiviral effect of human fibroblast interferon. Interferon antiserum prevented t... | 778,494 | [
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The reform of ambulatory care: a financial paradox. | The purpose of this paper is to examine the financial factors which have effectively constrained the movement toward major reform in the out-of-hospital medical care area within this country. Analysis of the current economic picture in the health field leads inescapably to the conclusion that the major wave of new out-... | 778,509 | [
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Genetic activity of the antimicrobial food additives AF-2 and H-193 in Saccharomyces cerevisiae. | The genetic activity of the antimicrobial food additives AF-2 and H-193 has been investigated in Saccharomyces cerevisiae. The strains chosen for the present studies were D5 for the induction of mitotic recombinational events and XV185-14C for the induction of reversion of the mutants lys1-1, his1-7 and homs3-7. When t... | 778,607 | [
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The resistance factor to Plasmodium vivax in blacks. The Duffy-blood-group genotype, FyFy. | Duffy-blood-group-negative human erythrocytes, FyFy, are resistant to invasion in vitro by Plasmodium knowlesi. The FyFy genotype is found predominantly in African and American blacks, who are the only groups completely resistant to infection by P. vivax. To determine if the FyFy genotype is the vivax resistance factor... | 778,616 | [
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[Autologous skin grafts in laparoceles]. | The theoretical, practical and experimental premises of autologous skin graft in the treatment of laparocele according to the technique of Zavaleta and Uriburù are discussed. The validity of the technique, already acknowledged by other workers, is confirmed by personal experience of operations on geriatric patients. | 778,664 | [
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Transfer factor - hypotheses for its structure and function. | Transfer factor (TF) is a dialyzable extract from primed lymphocytes that is able to transfer specific delayed hypersensitivity from one animal to another. On the basis of available data we suggest that TF is a polypeptide with a molecular weight below 15,000 daltons. We hypothesize that TF is the variable light or hea... | 778,717 | [
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Penetrating keratoplasty: a computer analysis. | A computer analysis of 87 penetrating kertoplasties done in a uniform manner by a single surgeon revealed the following: 1. On a statistical basis small grafts (7.0 mm) provided better visual acuity than larger grafts (8.0 mm). 2. On a statistical basis small grafts will be clearer postoperatively than larger grafts. 3... | 778,719 | [
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Soft tissue trauma. | Prior to surgical repair of maxillofacial injuries, a surgeon should formulate an operative plan based upon a careful and complete pre-operative analysis. Obviously this may effect the timing of repair. However, it is more efficacious to delay surgery for up to 24 hours than to close lacerations over a lacerated facial... | 778,743 | [
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Operative treatment of pressure sores in paraplegics by rotation flap. | Sixty rotation flaps (in 40 paraplegics) to cover pressure sores and unstable scars in the region of the buttocks are reported. There were 12 complications (20 per cent), none jeopardising the result of the operation. Advantages of the rotation flap are its good blood supply if generously outlines and the possibility o... | 778,746 | [
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[Lipid calcium interactions in experimental and human nutrition (author's transl)]. | A balanced intake of alimentary lipids is necessary for calcium and phosphorus absorption, as for growth and calcification of bone. In lipid deprivation or excess, important disorders of phospho-calcic metabolism appear particularly in young growing subjects. The qualitative content of ingested fats has, too, a great i... | 778,752 | [
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[Survival and humoral response of mice infected with Treponema pallidum (author's transl)]. | To judge the pathogenicity of Treponema palllidum in mice, we inoculated two groups of animals. 1) One with a normal immune system : adult Swiss mice. 2) The other with an immune system presenting a defect in T cells : athymic Nude mice. No lesions appeared at the points of inoculation and the survival of these animal... | 778,756 | [
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Induction of secific immunological tolerance to histocompatible renal and skin allografts after donor strain spleen implantation. | Spleens from Lewis X BN F1 hybrid rats were directly anastamosed to the circulation of parental strain Lewis rats by a microvascular technique; no immunosuppressive drugs were given. Donor spleens enlarged massively during the first month after implantation, then grew gradually smaller over succeeding months without co... | 778,833 | [
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Ribosomal proteins of Escherichia coli that stimulate stringent-factor-mediated pyrophosphoryl transfer in vitro. | Guanosine tetra- and pentaphosphate, (p)ppGpp, can be synthesized in vitro in a reaction containing only the enzyme (stringent factor), salts, and substrates (nonribosomal system). This reaction is greatly stimulated upon addition of methanol (methanol system) or by ribosomes, mRNA, and tRNA (ribosome system). Here we ... | 778,846 | [
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Cannula system for local stimulation of the rat brain. | The cannula design permits microinjection and push-pull perfusion, plus the use of a pressure probe for intraventricular placements. | 778,857 | [
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Treatment or punishment? A nineteenth-century scandal. | In psychiatry the relationship between treatment and punishment is variable and ambiguous. It has always been possible to employ physical methods of treatment for punitive ends, against which the introduction of liberal policies is no complete safeguard. Indulging one's personal animosities towards a difficult or viole... | 778,878 | [
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Life-history tactics: a review of the ideas. | This review organizes ideas on the evolution of life histories. The key life-history traits are brood size, size of young, the age distribution of reproductive effort, the interaction of reproductive effort with adult mortality, and the variation in these traits among an individual's progeny. The general theoretical pr... | 778,893 | [
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Computed tomography: demonstration of contrast medium within cystic tumors. | Two cases demonstrated that intravenously injected contrast medium entered cystic lesions. It appears that both vascular opacification and transgression of the blood-brain barrier play major roles in contrast enhancement. | 778,910 | [
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Oral trypsin-inhibitor-induced improvement of the exocrine and endocrine pancreatic functions in alloxan diabetic rats. | Studies are presented dealing with the effect on the exocrine and endocrine pancreas of long-term oral trypsin inhibitor administration to alloxan diabetic rats. Three categories of rats were used: a) normal rats, b) alloxan diabetic rats, and c) alloxan diabetic rats treated with the trypsin inhibitor. 1. The concentr... | 779,003 | [
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Spongy bones in prehistoric America. | A well-preserved mummified child from about A.D. 1200 was recovered fron Canyon de Chelly in northeastern Arizona in 1971. Striking skull changes were found and microscopic, ultrastructural, and cytochemical studies confirm the diagnosis of porotic hyperostosis that resulted in spongy bone appearance. We suggest that a... | 779,029 | [
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Intraclonal histocompatibility in a parthenogenetic lizard: evidence of genetic homogeneity. | A total of 175 skin grafts were transplanted among 20 individuals belonging to two separate populations of the parthenogenetic lizard Cnemidophorus uniparens. Of these, 98.8 percent were permanently accepted, which indicates that all individuals of each population may be genetically identical. These results further sug... | 779,030 | [
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Correction of extensive neck contractures with local flaps and split- and full-thickness grafts. | A technic of combined split-thickness and full-thickness skin grafts and local flap closure for extensive deep cicatricial neck contractures is presented. The head and neck are mobilized by excision of limiting tissues. The lateral neck skin is mobilized to be rotated anteriorly as flaps, and a full-thickness skin graf... | 779,040 | [
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A simple technique for closure of temporary cystostomy. | To overcome the problem of persistent urinary wound discharge after prostatectomy with temporary cystostomy, a simple suture technique is introduced. Two monofilament nylon sutures are inserted through the abdominal wall, tangentially to the dome of the bladder, together making a purse-string suture around the cystosto... | 779,082 | [
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Volumetric instillation of fixatives and inert substances into mouse lungs. | Mouse lungs were instilled with various fixatives to establish the optimum volume necessary to fix the lung without distortion and to compare the efficacy of the fixatives. Fixation with either Stieve's or Bouin's fluid was found preferable to 2.5% and 5% glutaraldehyde, 4% neutral buffered formalin, and to a mixture o... | 779,144 | [
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A modification of the rapid Golgi method. | An extremely rapid Golgi procedure for immersion impregnation of the whole brain of the frog Rana esculenta is described. It uses an isotonic 2% osmium tetroxide solution buffered with sodium barbital at pH 7.2 that has previously been used for electron microscopy. To 15 ml of this solution 85 ml 3% potassium dichromat... | 779,149 | [
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0.1723051,
0.... |
Recipient selection for renal retransplantation. | Analysis of over 1,000 kidney retransplants revealed an important effect of first graft duration and presensitization on graft outcome. Second cadaver donor grafts into patients without preformed cytotoxic antibodies and a first graft duration of more than 12 months survived at a high 1-year rate of 71 +/- 6%, in contr... | 779,172 | [
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[Operative therapy of elephantiasis penis by skin transplantation (author's transl)]. | From 1960 to date, there have been four cases of elephantiasis penis in the urologic clinic of the Katharinenhospital in Stuttgart, which were operated on by skin transplantation. The causes of elephantiasis penis are discussed, and the surgical procedure is presented in detail. Finally, the outcome as far as appearanc... | 779,209 | [
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... |
[The rat visual cortex. Cytoarchitecture and stereotactic parameters]. | In the present investigation the visual cortex of the albino rat was analyzed. On the basis of cytoarchitectonic criterions we can demarced the area striata (field 17) from a medial (field 18) and lateral (field 18a) lying peristriatic area. There are differences in the cortical structure not only between the striate a... | 779,304 | [
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... |
[On the complex formation of proteins with cu ions under acidic conditions]. | In order to determine the influence of copper additives on the protein digestibility, the complex formation of proteins with Cu ions under acidic conditions (pH=2.2) was investigated. Isolated soja-protein (300 mg) resp. pepsin was mixed with 10 mumol (2.49 mg) CuSO4-5H2O and dialysed against low molecular complexing a... | 779,338 | [
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0.375703... |
[Propranolol and arterial hypertension: study with frequent daily checking of blood pressure and serum levels after 1 week of treatment]. | In order to establish correlations between serum levels of Propranolol, blood pressure in hypertensive patients and cardiac rate, these parameters have been recorded at three different times in a day and after a week. This study points out that therapeutic response is variable. However the patients may be classified in... | 779,369 | [
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... |
Billroth I gastric resection versus truncal vagotomy and pyloroplasty in the treatment of gastric ulcer. | Forty-five patients with benign gastric ulcers were treated by truncal vagotomy and pyloroplasty or Billroth I gastric resection in a randomized, controlled trial. Postoperatively, one Billroth I patient died. During the follow-up recurrence occurred in three patients treated by vagotomy, but in no Billroth I patient. ... | 779,383 | [
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0.06575731,
0.4403874,
0.03824949,
0.0... |
Escherichia coli O antibody content in milk from healthy Swedish mothers and mothers from a very low socio-economic group of a developing country. | The antibody content of milk from healthy Swedish mothers was compared with that of milk from mothers of a very low socio-economic group in a developing country. Antibodies of various immunoglobulin classes against E. coli O antigens were determined with the enzyme-linked immunosorbent assay (ELISA). The milk antibodie... | 779,397 | [
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... |
Transformation of Escherichia coli by R404 factor DNA and properties of the transformants. | Three r-determinants (Cb Cm Cf) out of eight present in R404 factor were transferred in transformation of Escherichia coli by the plasmid DNA isolated from minicells. The r-determinants acquired in this way formed the replicon tr404-1 and were untransferable by conjugation unless another self-transmissible plasmid was ... | 779,405 | [
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Cummings Memorial Lecture - 1975. The market basket: food for thought. | The world food crisis is as critical today as when it was debated at the 1974 World Food Conference in Rome. Since the United States and Canada-and to a lesser extent, Australia and New Zealand-lead in the production of corn, wheat and soybeans, the North American "bread basket" has become the "market basket" of the wo... | 779,439 | [
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0.07316317,
0.3963051,
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Reared in adversity: institutional care of children in the 18th century. | The earliest public pediatric care of the 18th century in this country took the form of "outdoor relief." Institutional care followed, first almshouses were built; then orphanages, hospitals, and dispensaries. Almshouses not only included workhouses but provided comprehensive medical services. Throughout the 18th centu... | 779,457 | [
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0.1014225,
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Galactorrhea-amenorrhea: psychological interaction with neuroendocrine function. | Further substantiation of the interaction between psychological disease and the onset of galactorrhea-amenorrhea is presented in women who underwent intensive psychometric and neuroendocrine evaluation prior to the use of the dopamine against 2-Br-alpha-ergocryptine (CB-154). Normalization of a previously distorted psy... | 779,478 | [
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0.2774203,
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... |
Treatmen of keratomycosis with amphotericin B 0.15%. | Amphotericin B 0.15% was tolerated and effective in the treatment of fungal ulcers of the cornea. In a series of 12 ulcers, four from which Fusarium was cultured, all responded to medical treatment. The mean final visual acuity in 11 of the 12 eyes with an adequate follow-up was 20/40. | 779,483 | [
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0.07858663,
0.287563,
0.1180896,
0.112303... |
A preliminary report on experienced closed-circuit television users. | In an attempt to describe the use and usefulness of closed-circuit televisions (C.C.T.V), a preliminary follow-up study of 27 veterans was undertaken by the Western Blind Rehabilitation Center. The veterans had been loaned C.C.T.V.'s by the Veterans Administration and represented a wide range of ages, backgrounds, and ... | 779,489 | [
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0.1175623,
0.05857308,
0.07693823,
0.2025232,
-0.2352... |
Classification of peripheral nerve fibres. An historical perspective. | The historical development of the nomenclature used to describe peripheral nerve fibres is described. Some of the properties of nerve fibres and their maturation are discusses. It is suggested that when grouping fibres by their conduction velocities the original terminology introduced by Erlanger and Gasser41 (i.e. A-a... | 779,513 | [
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0.1745899,
0.1447967,
0.... |
The development of apparatus for intermittent negative pressure respiration. (2) 1919-1976, with special reference to the development and uses of cuirass respirators. | This paper and the one that preceded it1 have traced the development of the design and use of negative pressure ventilators from their origins in the early nineteenth century to the present day. Their maximum use was in the nineteen-forties and the early fifties after which they were quite rapidly replaced in the treat... | 779,520 | [
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0.1871203,
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Immune responses of the bovine fetus and neonate to Escherichia coli: quantitation and qualitation of the humoral immune response. | The humoral immune responses of fetuses and neonates of Escherichia coli O:26:K60:NM were studied in 26 Angus-Hereford crossbred calves. Bacterin (5.0 X 10(10) organism) was injected in utero directly into the amniotic fluid of seventeen 7- to 8.5-month-old fetuses (principals). Saline solution was injected in the same... | 779,538 | [
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0.1446876,
0.2588886,
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0.07905... |
Effect of bovine neutrophil maturity on phagocytosis. | The ability of immature circulating neutrophils to phagocytose foreign particles was determined. One quarter of each of 4 cows, which were free of mastitis and pathogens and had milk somatic cell counts of less than 1 X 10(6) cells/ml, was infused with endotoxin of Escherichia coli (0.5 mg in 3 ml of saline solution) t... | 779,542 | [
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0.06621947,
0.3183298,
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0.3365113,
0.3249221,
0.2439647,
... |
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