title stringlengths 0 901 | abstract stringlengths 3 9.89k | PMID int64 22 25.3M | embedding listlengths 768 768 |
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Effect of ethanol on angina pectoris. | We evaluated the effect of ethanol on exercise performance until angina in 12 patients in a double-blind, randomized study. The mean resting heart rate times systolic blood pressure was not changed after Fresca but was increased after 2 ounces of ethanol (P less than 0.001) and after 5 ounces of ethanol (P less than 0.... | 779,561 | [
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[Massive pulmonary hemorrhage successfully treated with mechanical respiration and CPAP (author's transl)]. | A newborn baby with massive pulmonary hemorrhage at two and a half hours of life is reported. She was successfully treated with mechanical respiration and continuous positive airway pressure. The pathogenetic mechanisms and mode of action of the applied treatment is discussed. | 779,560 | [
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Technique for the coronary snake graft operation. | The use of one end-to-side anastomosis with side-to-side technique for all additional vein-coronary anastomoses has given continually good results and has been used in 227 of 411 patients undergoing vein graft operations, including all multiple graftings done since April, 1972. The operative mortality was 4.6%. Arterio... | 779,687 | [
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[The antigenic structure of vibrions studied by means of agglutination and fluorescent antibodies]. | Cross immunofluorescent and serological studies were made of strains of Vibrio coli of different forms-a short, commashaped strain and other long, spiral-shaped and serpent-like strains isolated from swine. Some standard strains of Vibrio foetus were also included for comparison. An antigenic difference was established... | 779,698 | [
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The "lazy-T" correction of ectropion of the lower punctum. | The "lazy-T" technique consists of a surgical horizontal and vertical shortening of the involved portion of the lower eyelid. As a result of the surgical procedure, the lid margin is restored to its normal relationship with the globe. The punctum is reestablished into its normal anatomical position in the proximity of ... | 779,732 | [
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[Clinical problems after the use of polyestercomponents in total hip replacement (author's transl)]. | Follow up studies of total hip replacement using polyester as a component of the alloplastic joint have shown that this material causes soft tissue reaction and osteolysis. The problem is demonstrated in this paper. | 779,735 | [
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[Scoliosis, metabolism and growth of the vertebral column (author's transl)]. | Modern investigators incline to the opinion, that more biochemical than biomechanical disorders take part in cause of the "idiopathic'' scolioses. It seems, however, that there is not only one cause but more in some subgroups. Idiopathic scolioses, which have symptomes of arachnodactyly, seem to be a big one of these s... | 779,736 | [
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Correlation between the immunoadjuvant activities and pyrogenicities of synthetic N-acetylmuramyl-peptides or -amino acids. | A total of 14 different N-acetylmuramyl-peptides or -amino acids with or without configurations inherent to bacterial cell wall peptidoglycans were synthesized and their pyrogenicities on intravenous injection into rabbits were tested. N-Acetylmuramyl-peptides, and especially N-acetylmuramyl-L-alanyl-D-isoglutamine and... | 779,765 | [
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Fluorescence energy-transfer measurements between coenzyme A and flavin adenine dinucleotide binding sites of the Escherichia coli pyruvate dehydrogenase multienzyme complex. | The interaction of the pyruvate dehydrogenase multienzyme complex from Escherichia coli with 1,N6-etheno-CoA (epsilonCoA) and coenzyme A (CoA) has been investigated using equilibrium binding, steady-state fluorescence, and fluorescence lifetime measurements. A procedure for the resolution of the pyruvate dehydrogenase ... | 779,833 | [
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[Phospholipid composition in thermosensitive mutants of Escherichia coli (author's transl)]. | Quantitative phospholipid composition was investigated on various thermo-sensitive mutants of Escherichia coli K 12. Phosphatidylethanolamine was the major component. Three mutants (T1, T46 and T5) grown at 40 degrees C, had more anionic phospholipids (phosphatidylglycerol and diphosphatidylglycerol) and less bipolar p... | 779,837 | [
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The biosynthesis of the thiazole moiety of thiamine in Salmonella Typhimurium. | The mechanism of biosynthesis of 4-methyl-5-beta-hydroxyethyl thiazole, the thiazole moiety of thiamine was studied in Salmonella typhimurium. Using the adenosine derepression technique the incorporation of various 14C-labeled precursors was determined. We found that;e1Me-14C]methionine, [2-14C]methionine, [U-14C]alani... | 779,848 | [
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Peptide substrates for chymosin (rennin). Kinetic studies with peptides of different chain length including parts of the sequence 101-112 of bovine k-casein. | Kinetic parameters have been determined for the reaction between milk-clotting chymosin (EC 3.4.23.4) and a series of peptides (or their methyl esters) including the amino acid sequence around the enzyme-sensitive Phe(105)-Met (106) bond the bovine k-casein. In particular, the influence of the substrate's chain length ... | 779,850 | [
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L-tryptophan in depression. | L-tryptophan, the amino acid precursor of serotonin, was administered to 16 depressive patients in a double-blind study of its potential antidepressant efficacy. Antidepressant responses were observed in one of ten unipolar patients and in three of six bipolar patients. These results are discussed in the context of pos... | 779,855 | [
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Effects of hyperosmolality on candidacidal activity of human neutrophil polymorphonuclear leukocytes and on clumping of Candida albicans by human serum. | Hyperosmolalities comparable to those of the renal medulla did not altered the clumping of C. albicans by human serum but diminished ingestion and evenmore the killing of C. albicans by human polymorphonuclear leukocytes (PMN). | 779,860 | [
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Circumcaval ureter: a report of four cases in children with a review of the literature and a new classification. | 4 cases of circumcaval ureter presenting in childhood are reported. A review of the literature reveals that most cases recieve attention only later in life at a time when ureteric changes are not so readily reversible. A study of the course of the ureter reveals that 2 forms can be distinguished: a common Type I with a... | 779,921 | [
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Prophylactic antibiotic therapy and heart valve replacement. | Patients undergoing cardiac bypass for heart valve replacement maintained adequate blood concentrations of cloxacillin throughout the duration of bypass, provided their initial blood concentration was in the therapeutic range. Blood levels related to the time between the last preoperative dose of antibiotic and operati... | 779,941 | [
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A focus of hyperendemic Plasmodium malariae-P. vivax with no P. falciparum in a primitive population in the Peruvian Amazon jungle. | Findings in a sample population in southeastern Peru with a very high rate of malaria infection, due to Plasmodium malariae and P. vivax with apparently no P. falciparum, are described. The proportion of persons with P. malariae in this sample population, as determined by slide examination, appears to be the greatest e... | 779,996 | [
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Antibody response in the intestinal secretions of volunteers immunized with various cholera vaccines. | The efficacy of various cholera vaccines in eliciting an intestinal antibody response was assessed in human volunteers who received oral live, oral killed, or parenteral cholera vaccines, or placebo. The intestinal immune response in terms of antibacterial and antitoxin antibodies was determined 2 and 4 weeks after imm... | 779,998 | [
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An extraorally activated expansion appliance for cleft palate infants. | A new lever-action expansion appliance is described which is designed specifically for use in infants with cleft lip and palate. An extraoral control knob allows for easy activation, while the important anterior cleft areas are left clear for premaxillary repositioning and clinical assessment. Activation is registered ... | 780,004 | [
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The occurrence of antibodies against single-stranded DNA in the sera of patients with acute and chronic leukaemia. | One hundred and seventy-five sera from thirty-three patients with acute myeloid leukaemia, forty-two patients with chronic myeloid leukaemia and twelve patients with acute lymphatic leukaemia were examined by a radioimmunological technique for the presence of antibodies against single-stranded and double-stranded DNA. ... | 780,020 | [
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Interdependence of thymic and neuroendocrine functions in ontogeny. | The immunological blockade of the adenohypophysis of athymic nude mice bearing allogeneic skin grafts prevents the reconstitution of transplantation immunity when such animals grafted with thymus, and the grafts are permanently accepted. Newborn and adult athymic mice have markedly diminished levels of prolactin in blo... | 780,022 | [
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Glomerular lesions in asymptomatic microscopic hematuria discovered on routine medical examination. | Renal biopsies from 145 patients with asymptomatic microscopic hematuria were studied with light microscopic, electron microscopic and immunofluorescence antibody techniques. The predominant lesions were a diffuse proliferative glomerulonephritis (mesangial hypercellularity) with focal epithelial crescents and focal se... | 780,026 | [
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Relationships between in vitro susceptibility and efficacy in experimental mouse infection-protection assay of cefazolin and cephalothin using Escherichia coli strains. | The disc sensitivity and minimal inhibitory concentrations (MIC) of cefazolin and cephalothin were compared against a series of Escherichia coli isolates. These data were correlated with the mouse protective doses of the 2 cephalosporins in animals infected with E. coli strains selected according to their various degre... | 780,071 | [
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New concepts in the formation, regulation of release, and metabolism of parathyroid hormone. | New information has elucidated many of the biochemical pathways in the formation, release and metabolism of parathyroid hormone (PTH). The hormone is biosynthesized in the parathyroid cells from two distinct precursors, or prohormones, that are modified by specific enzymic cleavages during the synthesis and intracellul... | 780,074 | [
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Carbenoxolone: a review of its pharmacological properties and therapeutic efficacy in peptic ulcer disease. | Carbenoxolone sodium has been shown to accelerate the rate of healing of both gastric and duodenal ulcers, but its overall value in duodenal ulcer is probably less because of the high rate of natural remission of duodenal ulcers. Further studies are required to decide whether it should be used prophylactically to delay... | 780,088 | [
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Luteinizing hormone and follicle stimulating hormone and the response to luteinizing hormone releasing hormone in relation to sex and age. | Serum follicle stimulating hormone (FSH) and luteinizing hormone (LH) before and after intravenous injection of luteinizing hormone releasing hormone (LHRH) were studied in 71 male and female subjects of various ages. Mean basal FSH and LH levels were not significantly different in the male groups, except that FSH was ... | 780,116 | [
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Bacterial endotoxin and impaired fetal development. | Small doses of E. coli endotoxin given to pregnant mice on the 13th day of pregnancy caused only a mild maternal illness but induced resorption of approximately half the number of fetuses in each mouse. The remaining live fetuses developed normally and showed no evidence of retarded growth or malformations. The weights... | 780,127 | [
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Alcoholism: its effect on hypothalamic pituitary gonadal function. | Both as the result of liver disease and of alcoholism per se, chronic alcoholics develop infertility, sterility, gonadal atrophy, hypoandrogenization, and feminization. The hypothalamic-pituitary abnormalities associated with alcoholism include hyperprolactenemia-increased estrogen-stimulated neurophysin levels, suppre... | 780,184 | [
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0.1698519,
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0.2101316,
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-0.... |
Lymphocyte immunological patterns in leukaemia: a review. | Investigation of the cell S--Ig in acute lymphocytic leukaemia (ALL), at the onset of relapse of the disease, shows quite marked differences from patient to patient according to the extent of the immunofluorescent-positive cells. They may vary from 0.5 to 25% or more. When these Ig-positive cells are treated with tryps... | 780,227 | [
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The effect of substitution of diaminopimelic acid by 4-hydroxy-diaminopimelic acid on the synthesis and degradation of murein in Escherichia coli 173-25. | Defects in the formation of the septum and gradually autolysis of cells occur when the dap-dependent mutant of Escherichia coli is grown in a medium with 4-hydroxy-diaminopimelic acid. When the culture grown in the presence of the labelled analogue is supplemented with the non-radioactive diaminopimelic acid a portion ... | 780,239 | [
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0.2725474,
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Growth and characterization of human skin epithelial cell cultures. | In 129 of 140 attempts, human skin cells were successfully cultured on the dermal collagen bed of sterile, dead pigskin. Diploid epithelial cells grew selectively on the collagen bed; fibroblasts grew on the glass surfaces of the culture dishes. The cultures could be subdivided physically up to six times at a 1:2 split... | 780,259 | [
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Secretion rates of LH and FSH during infusion of LH-FSH/RH in normal women and in patients with secondary amenorrhea: suggestive evidence for two pools of LH and FSH. | Normal women in the early follicular phase and in the luteal phase of the cycle, and patients with secondary amenorrhea received on consecutive days a rapid intravenous injection (50 mug) and a two or four-hour infusion (25 mug/h) of synthetic LH-FSH/RH. The responses of LH and FSH were evaluated by the measured plasma... | 780,363 | [
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Curing and caring -- a proposed method for self-assessment in primary care organizations. | Key research in the area of quality assessment is reviewed and a method for periodic assessment in primary care organizations is proposed. The suggested approach is designed for administrative, rather than research, purposes. Therefore, it focuses on indicators that are both practical and realistic for use in periodic ... | 780,379 | [
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Teaching social skills to isolated children. | The effects of a social skill training program on socially isolated children are reported. The training program was derived from the results of a previous study of the specific social skills that discriminated popular from unpopular children. Training effects in the present investigation were assessed on sociometric po... | 780,399 | [
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Chronically ill children. A psychologically and emotionally deviant population? | The study evaluated the psychosocial functioning levels of a group of chronically ill (diabetic, asthmatic, cystic fibrotic, and hearing-impaired) children across a battery of standardized personality instruments. The assessments were performed to provide a rigorous test of the popular hypothesis that chronically ill c... | 780,400 | [
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Mechanisms involved in elimination of organisms from experimental cutaneous Candida albicans infections in guinea pigs. | Experimental cutaneous Candida albicans infections were produced in guinea pigs either by using occlusive dressings over the organisms or by applying them to the shaved skin directly without occlusive dressings. In either model there was clearance of the infecting organisms from the skin by a process involving profuse ... | 781,132 | [
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Pattern formation in early developmental stages of amphibian embryos. | An internal factor (or factors), which determine the endoderm and the mesoderm anlage, seem to exist already in certain regions of the oocyte and very early developmental stages. The factor(s), which is (are) protein in nature, has (have) similar properties to the one isolated from chicken embryos. The induction of the... | 781,172 | [
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The development of regional pigmentation patterns in black and tan (at) mice. | Mice which express the black and tan (at)allele at the agouti locus have black dorsal and yellow ventral hairs. To determine the site of action of this allele, the kind of hair pigment produced by various dermal-epidermal recombinations of dorsal and ventral black and tan (at/at), ventral nonagouti (a/a) and ventral ye... | 781,177 | [
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Histologic evaluation of intraoral skin grafts and pedicle flaps in humans. | Histologic evaluation of biopsy specimens from six split-thickness skin grafts and seven pedicle flaps was made two months to 15 years after intraoral cancer reconstruction. In the transplanted skin, there was persistence of all epidermal layers with production of orthokeratin and melanin, and persistence of papillary ... | 781,193 | [
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Pharmacokinetics of methyldopa in man. | Single doses of methyldopa were administered orally and intravenously as aqueous solutions to 12 healthy volunteers in a crossover study. Serial plasma and urine samples were analyzed specifically for methyldopa and its O-sulfate conjugate. Kinetic analyses of the results indicated that methyldopa disposition could be ... | 781,212 | [
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Comparison of benefit-to-risk ratios of aspirin and fenoprofen: controlled multicentre study in rheumatoid arthritis. | The benefit-to-risk ratios of fenoprofen (2.4 gm/day) and aspirin (3.9 gm/day) were compared in a randomized, double-blind, 26-week parallel study involving 216 patients. Criteria for inclusion, exclusion, subjective, and objective evaluations were based on the PMA-FDA Nonsteroidal Anti-Inflammatory Drug Clinical Testi... | 781,231 | [
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A copper block method for freezing non-cryoprotected tissue to produce ice-crystal-free regions for electron microscopy. II. Evaluation using freeze fracturing with a cryo-ultramicrotome. | Two methods are described for fracturing unfixed, uncryoprotected mouse liver that had been frozen by contact with a copper block at liquid nitrogen temperature. The best method involved precise fracturing of a few microns of surface tissue with a cooled glass knife, using the Cryokit attachment of the LKB III ultrami... | 781,255 | [
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Genetic studies of coliphage P1. II. Relatedness to P7. | Using semiquantitative spot tests, 107 independently isolated amber mutants of P1 were shown to be rescued by a nonpermissive strain of Escherichia coli lysogenic for P7 (previously called phiamp), indicating extensive genetic relatedness between P1 and P7. The amount of rescue observed varied with mutants from differe... | 781,305 | [
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Intestinal perforation due to fecal impaction after renal transplantation. | Three renal allograft recipients suffered major intestinal complications shortly after the operation. Identification of diverticular disease, adequate preoperative bowel preparation, avoidance of excessive amounts of non-absorbable antacids, early ambulation, and periodic laxatives and stool softeners can prevent these... | 781,315 | [
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The definitive treatment of children with acute leukemia. | Current therapy has resulted in improved prognosis in previously untreated children with acute lymphocytic leukemia less than 16 years of age. The induction phase of chemotherapy should include the use of at least prednisone and vincristine. This combination should result in a hematologic remission in about 90 per cent... | 781,418 | [
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[Immunofluorescence and immunoelectron microscopic study of changes occurring in secondary reaction of popliteal lymph nodes in young and old rats]. | A comparative study of the secondary reaction of popliteal lymph nodes in young and adult rats was carried out. In one group of experiments secondary reaction was induced by bovine serum albumin (BSA), in the other one by peroxidase from horseradish. Antigen was administered with Freund adjuvant. It was established tha... | 781,524 | [
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Neuroradiological diagnosis of intraspinal tumors in children. | In the diagnosis of spinal and intraspinal space-occupying processes great importance attaches to radiologic plain film diagnosis, including special projections and tomography. Using refined evaluation methods, direct and indirect signs of tumors can be demonstrated in 30-50% of cases. Of decisive importance is the mye... | 781,550 | [
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[Effect of furosemide, potassium canrenoate and D-L-propranolol on blood pressure in spontaneously hypertensive rat]. | Spontaneously hypertensive rats (japanese strain) have been treated with furosemide, potassium canrenoate or d-l-propranolol. Present results indicate that: 1)furosemide admiinistration, from the 3rd to the 15th week of life, does not prevent the development of hypertension but the blood pressure rises more slowly in t... | 781,602 | [
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Cleavage of T4 species I ribonucleic acid by Escherichia coli ribonuclease III. | T4 Species I RNA, a molecule 140 nucleotides in length with some structural features very much like a tRNA, is specifically cleaved by an enzymatic activity in Escherichia coli extracts to give three segments with 19, 48 and 73 nucleotides. We report the purification and characterization of the E. coli RNase which clea... | 781,626 | [
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Patient selection for anticoagulant therapy in coronary heart disease. | Short-term anticoagulant therapy given after an acute myocardial infarction is directed toward preventing thromboembolism and is fairly safe. Long-term anticoagulant therapy prevents coronary thrombosis in selected patients with coronary heart disease (CHD), but carries an appreciable risk of hemorrhage. A decision for... | 781,648 | [
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New low resolution model for 50S subunit of Escherichia coli ribosomes. | Neutron low angle scattering studies of the 50S subunit of E. coli ribosomes with the contrast variation method reveals large fluctuations in the scattering density. A region of relatively low scattering density, rich in proteins, surrounds an RNA-rich core of higher scattering density. The centers of mass of the RNA a... | 781,676 | [
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Effects of amygdala lesions on taste aversions produced by amphetamine and LiCl. | Rats which sustained bilateral damage to the amygdala were treated with one of two diversely acting agents (either d-amphetamine sulphate 4 mg/kg, or lithium chloride 0.24 M) in a taste aversion paradigm. Both groups of animals showed an attenuation of the aversion on the first test day after the initial pairing with t... | 781,692 | [
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The fathers (not the mothers): their importance and influence with infants and young children. | This review is primarily concerned with the behavior and influence of fathers with respect to their infants and children in early childhood as a mediating variable in forms of psychopathology. Three developmental periods are surveyed in relation to what is known of paternal behavior and its influences on the child: pre... | 781,710 | [
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Congenital malformations in infants of diabetic mothers. | In a series of 701 infants born to diabetic women between 1950 and 1974 ,57(8-1 percent) had congential malformations which is a rate three to four timeshigher than in the normal populations of Birmingham.. In 26 cases(3-8 per cent) the malformations were fatal and accounted for 26 per cent of the perinatal mortality i... | 781,716 | [
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[The lymphocyte transformation test with the bedsonian antigen (bedsonian LTT) in old and recent Fiessinger-Leroy-Reiter syndromes and in ankylsoing spondylarthritis. Additional study]. | The lymphoblastic transformation test in the presence of bedsonian antigen was positive in 72 per cent of the cases confirmed Fiessinger-Leroy-Reiter syndrome, while it was negative in all the controls. This test remains positive over a long period since it was found to be positive in 69.75 per cent of old cases of FLR... | 781,787 | [
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Triple arteries in renal transplantation - a preliminary report. | Kidneys with triple arteries were transplanted to seven recipients. As no problems related to the reconstruction procedure were experienced it was deemed justifiable to accept grafts with triple arteries. | 781,823 | [
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0.1922324,
0.08617427,
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-0.3116193,
0.1618231,
0.07938504,
0.1921787,
0.1202143,... |
Renography using the gamma camera and the intertechnique cinescintigraphy system. A review of the current applications. | The application and use of radio-isotopes in nephrology have been neglected by clinicians. The indications and techniques used in the renogram and renal scan in the light of our experience over 2 1/2 years are presented. Although these methods are finding ever-increasing applications, the main uses at this stage are th... | 781,871 | [
-0.08769546,
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Randomized clinical trial of antithymocyte globulin in cadaver renal allograft recipients: importance of T cell monitoring. | Despite incontrovertable evidence demonstrating the unique immunosuppressive capabilities of antihymocyte globulin (ATG) in animals, its value in clinical transplantation has remained inconclusive. A multicenter, prospective study was undertaken in an attempt to determine this value. Cadaver renal allograft recipients ... | 781,887 | [
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0.037068,
-... |
Long-term beclomethasone dipropionate aerosol therapy in juvenile asthma. | Following a short-term clinical trial reported elsewhere, beclomethasone dipropionate aerosol has been given to 15 children with asthma for between 2 1/2 and 3 years except for a short placebo period after the first year. Month-by-month records of wheezing, peak flow rate, and other treatments used are presented for th... | 781,906 | [
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0.4057236,
0.1389219,
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[Somatic polyploidy in animal embryogenesis]. | The evidence provided in our laboratory on somatic polyploidy is reviewed. The development of some embryonal cell populations being taken as an example, the main problems of somatic polyploidy are discussed: somatic polyploidy and proliferation, growth, cell differentiation and specialization, the significance of polyp... | 781,960 | [
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A new biomaterial for the control of infection in the burn wound. | A synthetic dressing has been developed that isolates the burn wound to protect patients from microbial contamination. This dressing is unique as it is formed from a 2-component system directly on the wound, leaving no voids for microbial proliferation. The synthetic cover, HYDRON Burn Dressing, adheres to the entire w... | 781,984 | [
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[Surgical tactics in hemorrhage from the upper segments of the digestive tract]. | The results of surgical treatment of 100 patients with hemorrhage from the upper digestive tract (except gastric cancer and hepatic cirrhosis, complicated with bleeding esophageal varices) are discussed. The role of gastrotomy is emphasized, while vagotomy and drainage operations do not seem to be greatly warranted in ... | 781,994 | [
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0.1016183,
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0.3783746,
0.02962846,
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... |
The reaction of the cerebral cortex to chronically implanted plastic needles. | Plastic (araldite) needles were implanted in the cerebral cortex in order to evaluate changes produced by an indwelling and relatively inert foreign body. The implants were removed together with surrounding cortex after 4-723 days and the implant-CNS boundary analyzed by light and electron microscopy. Three border cond... | 782,142 | [
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0.2957956,
... |
Carl Langenbuch and the first cholecystectomy. | Cholecystectomy is the second most common operation performed today, but its founder, Carl Langenbuch, has received little recognition. The evolution of biliary surgery to the first cholecystectomy is traced. Contributions of von der Wiel, Petit, and Thudicum are reviewed. The cases of the first cholecystotomy by John ... | 782,269 | [
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0.1728456,
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0.039... |
NIH conference. Dopamine- -hydroxylase. Basic and clinical studies. | Dopamine-beta-hydroxylase, the enzyme responsible for conversion of dopamine to norepinephrine, is released along with catecholamines from the adrenal medulla and from sympathetic nerve endings. The properties and mechanisms of the enzyme's action are discussed and its distribution described. Dopamine-beta-hydroxylase ... | 782,312 | [
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The distributions of subunit numbers and subunit sizes of enzymes: a study of the products of 100 human gene loci. | 1. A tabulation of subunit numbers and subunit sizes of a series of enzymes which have been studied electrophoretically in man is presented. The series of subunit numbers cover the isozyme products of 100 distinct gene loci. For 99 of these, estimates of subunit size are given. 2. The distribution of subunit numbers in... | 782,337 | [
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0.... |
Colonization of the intestinal tract of conventional mice with Candida albicans and treatment with antifungal agents. | Conventional mice inoculated with Candida albicans per os were unable to maintain this organism in the intestinal tract as judged by decreasing numbers of yeast recoverable from feces. After inoculation with 10(7) cells/mouse, fecal counts ranged from 10(5) cells per g of feces to 5 x 10(3) cells per g of feces during ... | 782,356 | [
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0.1349922,
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0.1550861,
0.179075... |
A rapid method for processing liver biopsy specimens for 2 micron sectioning. | We will describe a procedure for the preparation of thin sections (2 micron thick) of percutaneous liver biopsy specimens for routine histological analysis. The process results in better preservation of both cellular and structural detail. The thinner sections provide clearer definition of inflammatory infiltrates, cel... | 782,398 | [
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0.05028349,
0.09510659,
0.01419867... |
Prednisone and azathioprine compared to prednisone plus low-dose azathioprine and cyclophosphamide in the treatment of diffuse lupus nephritis. | A 1-year double-blind crossover study comparing prednisone and azathioprine to prednisone plus low-dose azathioprine and cyclophosphamide was carried out in 14 patients with diffuse lupus nephritis. Low-dose triple therapy had no apparent therapeutic advantage over prednisone plus azathioprine. Cyclophosphamide-induced... | 782,464 | [
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[Clinical trial of the antibacterial combination sulfamoxole/trimethoprim (CN 3123)/Third communication: Clinical results of a field trial with CN 3123 in bronchopulmonary and ENT (ear/nose/throat) infections (author's transl)]. | The following conclusions emerged from an analysis of the therapeutic results documented during the clinical trial of N1-(4,5-dimethyl-2-oxazolyl)-sulfanilamide (sulfamoxole) and 2,4-diamino)-5-(3,4,5-trimethoxy-benzyl)-pyrimidine (trimethoprim) (CN 3123, Nevin, Supristol) in bacterial infections of the respiratory tra... | 782,475 | [
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... |
Radioactive colloidal solutions and suspensions for medical use. | Radioactive colloidal solutions and suspensions are being widely used in the diagnosis and treatment of various diseases. The author considers the behaviour or radioactive disperse preparations in the body and devotes particular attention to the reasons for isotope transition from the colloidal to the ionic state. Ques... | 782,479 | [
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0.2295165,
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Depression of bursal follicle formation by Candida albicans infections. | Sub-lethal i.v. inoculations of Candida albicans into 12-day-old chick embryos have been shown to cause a depression of follicle formation in the bursa of Fabricius. This depression occurred in the absence of any infection in the bursa, although candidal encephalitis was a frequent manifestation of the disseminated inf... | 782,498 | [
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0... |
Leucosis and skin: acute lymphoid immunoblastic leukaemia. | The clinical course of a patient with acute lymphoid immunoblastic leukaemia and prominent nodular haemorrhagic skin lesions is described. Cytological, cytochemical and electronmicroscopic studies were performed on bone marrow and skin blast cells. The absence of surface immunoglobulins and of the other markers for B l... | 782,503 | [
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... |
Stimulaiton of insulin biosynthesis in isolated mouse islets by L-leucine, 2-aminonorbornane-2-carboxylic acid and alpha-ketoisocaproic acid. | An immune binding technique was used for measuring the effects of certain amino acids on the rate of insulin biosynthesis. [13H]phenylalanine served as the radioactive precursor for insulin synthesized by isolated mouse pancreatic islets. L-Leucine was found to stimulate the insulin biosynthesis and this effect was obs... | 782,528 | [
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0.6034806,
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Physical properties of muscle cell membranes during fusion. A fluorescence polarization study with the ionophore A23187. | 1. The fluorescence polarization of A23187 is used to detect physical changes in myoblast membranes produced by Ca2+ concentrations which are able to trigger fusion. Temperature scans reveal a Ca2+-dependent fluidity increase in the microenvironment of the ionophore above 37 degree C. 2. Time-dependent polarization mea... | 782,544 | [
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... |
Anthranilate synthase-anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferases from Salmonella typhimurium. Purification of the enzyme complex and analysis of multiple forms. | 1. The anthranilate synthase-anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase enzyme complex (chorismate pyruvatelyase (amino-accepting), EC 4.1.3.27) - (N-(5'-phosphoribosyl)-anthranilate: pyrophosphate phosphoribosyltransferase, EC 2.4.2.18), from Salmonella typhimurium has been purified with high... | 782,548 | [
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0.1602676,
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... |
Translation of a stable mRNA fraction from sporulating cells of Bacillus thuringiensis in a cell-free system from Escherichia coli. Structural homologies between the native crystal protein and the products synthesized in vitro. | Stable messenger RNAs from sporulating cells of Bacillus thuringiensis were translated in vitro in cell free system from E. coli. The mRNA fraction used was extracted from cells treated at t4 of sporulation time with rifampicin for 10 minutes at 30degreesC. This stable-mRNA enriched fraction directed the synthesis of p... | 782,551 | [
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0.008841833,
0.3233938,
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0.05299047,
-0.1765142... |
The methylation of tRNA. | The methylation of tRNA is a post-transcriptional modification which is achieved by specific enzymes, the tRNA methylases, with S adenosylmethionine as a methyl donor. The level and pattern of methylation are characteristic of the tRNA species and origin. Abnormally methylated tRNAs have been obtained, in vivo and in v... | 782,564 | [
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0.1... |
Specific immunodiagnosis of human hydatidosis by the enzyme linked immunosorbent assay (E.L.I.S.A.). | The enzyme-linked-immunosorbent-assay (E.L.I.S.A.) using whole and purified hydatid antigens was applied to the diagnosis of human hydatid disease. This sensitive and economical method provides new possibilities for the specific diagnosis of parasitic diseases by automated procedures. | 782,577 | [
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0.1095005,
0.08839112,
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Fed batch culture of Saccharomyces cerevisiae: a perspective of computer control to enhance the productivity in baker's yeast cultivation. | A means to avoid the glucose effect in the production of baker's yeast from glucose and/or molasses in a fed batch culture by controlling the feed rate of fresh medium with an ad hoc measurement of the respiratory quotient, RQ, is presented. The feed rate is changed stepwise here such that the value of RQ ranges from 1... | 782,581 | [
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0.1952945,
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Large-scale disintegration of microorganisms by freeze-pressing. | A semicontinuous press has been constructed for the disintegration of microorganisms and other biological material by freeze-pressing, i.e., pressure extrusion of frozen material through a narrow hole. The material to be freeze-pressed is frozen in the form of cylindrical rods, which fit into the pressure chamber and a... | 782,582 | [
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... |
[Mitosis in the tubular epithelium of allotransplanted dog kidney during the early periods following transplantation]. | Cells dividing by mitosis were revealed in the tubular epithelium of 5 of 23 allografted kidneys of mongrel dogs. These mitoses were localized in the proximal and distal convoluted tubules (88 and 21 mitoses, respectively). Four pathological mitoses among 29 dividing epithelial cells were revealed 3 and 5 days after th... | 782,608 | [
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0.03446013,
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... |
Perfusion in the experimental preservation of the rat heart. | Rat hearts have been preserved for 24 hours using four different preservation solutions. The results suggest that the best preservation fluid is Tyrode's solution with Ficoll 5 per cent. A comparison of simple cooling of the heart and perfusion, either continuous or intermittent, has shown that intermittent perfusion o... | 782,621 | [
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0.0001474724,
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-0.1895781,
0.05837144,
0.07143357,
0.1858317,
... |
Wound infection in a children's hospital. | The operation wounds of 20 per cent of the children operated on in one surgical unit of a children's hospital became infected. Infection was commonest in the newly born operated on as emergencies, 50 per cent of whose wounds became infected. No connection was found between injection and nasal carriage of staphylococci.... | 782,626 | [
-0.128758,
-0.3712908,
-0.2327034,
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0.09114421,
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0.3411247,
0.3199381,
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0.0582287,
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-0.1817042,
-0.06318805,
0.158517,
-0.1085896,
0.075973... |
Colic as the sole symptom of urinary tract infection in infants. | Urinary tract infection was diagnosed in four infants whose sole symptom was persistent recurrent colic. There were no other clinical abnormalities. Three had abnormal radiologic findings in the urinary tract and one subsequently required nephrectomy. In the two others, radiologic findings were normal after 6 months an... | 782,676 | [
0.06174026,
0.1598802,
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0.01791308,
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0.2398949,
0.4215984,
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0.1911175,
0.118193,
-0.08560274,
... |
Methotrexate and citrovorum factor rescue in the management of childhood lymphosarcoma and reticulum cell sarcoma (non-Hodgkin's lymphomas): parolonged unmaintained remissions. | High doses of methotrexate (HDMTX), given in pulse infusions of 3 to 30 mg/kg body weight, were studied in 22 children with non-Hodgkin's lymphoma. Sixteen complete and five partial remissions were observed in 21 patients evaluable for remission induction. The dose of MTX was increased stepwise on consecutive treatment... | 782,684 | [
-0.2907035,
-0.1154135,
0.1313495,
-0.4243275,
0.06927764,
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0.02956856,
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0.2404459,
0.4260207,
0.09588175,
-0.05868697,
... |
Analog computer assisted beat-by-beat measurement of stroke volume and related variables in man. | A technique for the beat-by-beat measurement of stroke volume is described. Aortic blood velocity signals are obtained from a catheter-mounted electromagnetic velocity transducer and analysed by a purpose-built analog computer. The stroke volume is computed by integration of each period of systolic forward flow using t... | 782,707 | [
-0.3180625,
0.4538848,
-0.5089056,
0.2885734,
0.1249157,
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0.03570161,
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0.002517853,
0.16165,
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0.03866125,... |
Effect of the RelA gene on the synthesis of individual proteins in vivo. | We have shown that the relA gene can affect the rates of synthesis of many nonribosomal proteins in E. coli. We used rel+ and relA strains that contain a temperature-sensitive valyl tRNA synthetase. Upon transfer from a permissive temperature (30degreesC) to a semi-resitrictive one (36.5degreesC), these strains continu... | 782,722 | [
-0.1107259,
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0.1547115,
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0.1112044,
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0.1362953,
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0.02831673,
-0.07971622,
0.4115249,
0.2631547,
0.3232263,
0.2043187,
... |
The three-dimensional dynamic geometry of the left ventricle in the conscious dog. | The dynamic geometry of the left ventricle was assessed with the use of chronically implanted pulse-transit ultrasonic dimension transducers. The orientation of the transducers allowed the measurement of left ventricular minor and major axis diameters and equatorial wall thickness in the conscious dog. The left ventric... | 782,742 | [
-0.2504565,
0.4791214,
-0.1365561,
-0.1288043,
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-0.5463822,
0.1833069,
-0.09366,
0.04650719,
0.164835,
0.1542171,
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-0.2105008,
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0.2550865,
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0.3266307,
-0.3798158,
-0.243097,
0.3778649,
-0.2810211,
0.1168659,
0.114... |
An artefact in lactate dehydrogenase isoenzyme patterns, assayed by fluorescence, occurring in the serum of patients with end-stage renal disease requiring maintenance haemodialysis. | In patients with end-stage renal disease requiring maintenance haemodialysis we have observed that serum albumin becomes fluorescent (excitation 356 nm, emission above 405 nm). This fluorescence is detected in the fluorescent assay of lactate dehydrogenase (LDH) isoenzymes on thin-layer agarose creating the impression ... | 782,744 | [
-0.02837747,
-0.002645967,
-0.3100803,
-0.01199131,
0.1650723,
-0.1062576,
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0.292536,
0.1705852,
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0.01043871,
0.06896939,
0.08401274,
0.3149149,
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0.07033382,
-0.5886077,
0.0007032748,
-0.001853175,
0.1855577,
0.0755439,
0.291541,
-0.036879... |
Lupus nephritis: correlation between light, electron microscopic and immunofluorescent findings and renal function. | Percutaneous renal biopsies from 56 patients with systemic lupus erythematosus were studied to determine the relationship between renal function and the light microscopic, electron microscopic and immunofluorescent antibody findings. The glomerular lesions were classified into 5 major groups: diffuse membranoproliferat... | 782,752 | [
0.07037775,
0.3188109,
0.04995562,
0.2444177,
0.005997404,
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0.09472311,
0.006956233,
0.2862957,
0.01480741,
0.07454984,
0.1440772,
0.1265903,
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-0.1603439,
0.1759626,
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0.3711607,
-0.06515768,
-0.1257473,
... |
The incidence of spina bifida occulta in idiopathic scoliosis. | A review of the roentgenograms of the spine of 100 patients with idiopathic scoliosis and 371 parents and siblings used as controls, showed an incidence of spina bifida occulta of 34 per cent and 41 per cent in their siblings. There was no increase in the incidence of spina bifida occulta in the patients with idiopathi... | 782,757 | [
0.01470977,
0.2443994,
0.1530047,
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-0.1820652,
-0.3043538,
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-0.612678,
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-0.2172105,
0.08993792,
0.2237221,
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0.0009227612,
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0.2416047,
0.2967551,
-0.371672,
0.2447156,
0.3209347,
-0.01011322,
... |
Self states and performances of preadolescent boys carrying out leadership roles inconsistent with their social status. | A sample of 221 Boy Scouts was formed into (usually) 4-man teams which competed in 3 games of skill. 1 member of each team was randomly designated as its captain, with powers to administer and reward. All subjects took modified Thematic Apperception Tests (TATs) and adjective checklists. Captains who were already leade... | 782,798 | [
0.06642315,
0.3791862,
0.07214368,
-0.262516,
0.1486475,
-0.6402391,
-0.8044137,
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-0.03733282,
0.2652819,
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-0.3738936,
0.2136954,
0.01336229,
0.3102637,
0.1275333,
-0.07457565,
-0.03856413... |
[Evaluation of diagnostic parameters in chronic recurrent urinary tract infection in children. III. Pyuria, hematuria, and proteinuria (author's transl)]. | Pyuria, proteinuria and haematuria have been shown to be unreliable parameters for the diagnosis of bacteriuria in 171 children with 455 recurrences of chronic urinary tract infection. Bacteriuria caused haematuria in 5%, proteinuria in 18% and even pyuria in only 47% of all instances. Pyuria has been also found in 11%... | 782,812 | [
0.171681,
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-0.1130108,
0.1592011,
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0.05160501,
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0.1136623,
0.2838209,
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0.09298016,
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0.1875141,
0.3282581,
0.1122794,
0.205116,
0.1004404,
-0.2485683,
0.08... |
Effect of thyroid status on spontaneous and induced surges of luteinizing hormone. | This study was designed to describe the effects of thyroid status on the preovulatory surge of LH and to determine the site(s) at which these effects are exerted. The treatment of normal 4-day cycling rats with a hyperthyroid dose of thyroxine (T4, 20 mug/100 g BW/day) for 8 days resulted in surges of LH on proestrus w... | 782,856 | [
0.103415,
-0.05177719,
-0.3295351,
-0.2502192,
-0.2824389,
-0.4572322,
-0.08324072,
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0.2385063,
0.03493169,
0.3221855,
0.02160334,
0.03302471,
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-0.3912758,
0.296553,
0.1636219,
-0.1349918,
0.009208802,
0.3550975,
-0.09054635,... |
Influence of abnormal postural and sensory conditions on human sensorimotor localization. | A wide range of experiments exposing subjects to unusual postural, sensory, and gravitational conditions have been discussed. In general, regardless of the nature of the experimental intervention, changes in sensory localization and sensorimotor coordination resulted. After prolonged exposure to the abnormal stimulus s... | 782,862 | [
-0.3560138,
0.02606464,
-0.2449919,
0.1202128,
0.1297299,
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-0.4736787,
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0.373976,
0.1038087,
-0.1495733,
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-0.09211323,
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0.05909964,
-0.5201457,
-0.05813354,
-0.429653,
-0.1252558,
-0.1941562,
0.06521126,
0.1322078,
... |
Pharmacological and endocrinological studies on anabolic agents. | When used in connection with animal production the term "anabolic agents" covers a wide range. Ther steroidal male and female sex hormones are included in this list, as are the nonsteroidal estrogens. For the clinician and for the endocrinologist, anabolics are only steroids chemically related to testosterone and 19-no... | 782,871 | [
-0.2800849,
0.1417839,
-0.001082408,
-0.3111437,
0.05770858,
-0.3805453,
-0.3040101,
0.0003594096,
-0.004500729,
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-0.08819695,
-0.3771408,
0.1993495,
0.07000048,
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0.09311379,
-0.4593262,
0.2251011,
-0.04660416,
0.3355811,
0.1799316,
0.329125,
-0.185... |
Weak neuronal accumulation of octopamine in dopaminergic neurons of the rabbit retina. | Dopaminergic retinal neurons become weakly radioactive after the injection of tritiated octopamine into the vitreous, but no other neurons do so. This indicates the absence of any effective mechanism for the accumulation of octopamine in rabbit retina. | 782,904 | [
-0.04137674,
-0.2997041,
-0.2182151,
-0.1382519,
0.1509855,
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-0.1382401,
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0.1863619,
0.1997128,
0.08122374,
0.2279514,
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0.2942163,
0.2889121,
0.1353342,
0.1501221,
0.392389,
0.1103199,
... |
Topical corticosteroid therapy and its effect on the hypothalamic-pituitary-adrenal axis. | All clinically effective topical corticosteroids have the potential for suppressing the pitutary-adrenal axis if large amounts are applied under occlusion on extensive areas. Recovery of the axis function occurs rapidly. In children, however, the risk of chronic suppression of the adrenal axis function with impairment ... | 782,954 | [
0.1662817,
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0.0758935,
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0.2136823,
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0.2736381,
0.1487297,
0.08550338,
-0.0266069... |
The use of live attenuated influenza vaccine ts-1(E) in man. | Live temperature-sensitive influenza virus vaccines were tested in two volunteer experiments. The vaccine virus was originally derived from a temperature-sensitive mutant of influenza A/Great Lakes/1965 (H2N2) produced by chemical mutagenesis with 5-fluorouracil. The ts lesions of this strain were subsequently transfer... | 782,966 | [
0.2324999,
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0.2396791,
0.01957959,
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0.3253016,
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-0.09011044,
0.2111475,
0.6492422,
0.2771631,
0.09307307,
-0.4840535,
... |
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